Current Treatment Options in Oncology

Article	Citations
Role of Metastasis-Directed Therapy in Genitourinary Cancers	163
Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer	113
Current Approaches of Immune Checkpoint Therapy in Chronic Lymphocytic Leukemia	85
Antibody-Drug Conjugates for Melanoma and Other Skin Malignancies	72
Advances in the Pathogenesis, Diagnosis, Treatment, and Prognosis of Marginal Zone Lymphoma	60
Correction to: Antibody–Drug Conjugate Revolution in Breast Cancer: The Road Ahead	55
Current Therapeutic Landscape in Lower Risk Myelodysplastic Syndromes	53
“Off-the-Shelf” Allogeneic CAR Cell Therapy—Neglected HvG Effect	51
Whole Abdominal Radiotherapy in Bone and Soft Tissue Sarcomas: Indications, Techniques, Clinical Outcomes, and Future Directions	48
Clinical Application of Artificial Intelligence for Non-melanoma Skin Cancer	47
Combining Radiotherapy with Immunotherapy in Cervical Cancer: Where Do We Stand and Where Are We Going?	42
An Update on Temporal Bone Paragangliomas	42
Management of Fatigue in Patients with Advanced Cancer	40
Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers	40
Approach to Localized Squamous Cell Cancer of the Esophagus	39
Options and Considerations in the Management of Peritoneal Disease in Patients with Small Bowel Neuroendocrine Tumors	34
Recent Advances in Liver Transplantation for Hepatocellular Carcinoma	34
Small Cell Lung Cancer—An Update on Chemotherapy Resistance	33
The Role of Nursing in the Delivery of Cardio-Oncology	32
Perioperative Immunotherapy in Muscle-Invasive Bladder Cancer	32
The Review of Modified Intersphincteric Resection in the Treatment of Ultra-Low Rectal Cancer	32
Current Practice in Carcinoid Heart Disease and Burgeoning Opportunities	31
Revolutionizing Breast Cancer Therapeutics: Intersecting Frontiers of Precision Medicine, Nanotechnology, and Drug Delivery Innovations	29
Targets Selection for Precision Therapy of Relapsed/Refractory Multiple Myeloma: the Latest Advancements	29
Regorafenib for the Treatment of Sarcoma	28

Advances in Targeted Therapy for Metastatic Prostate Cancer	28
Essential Thrombocythemia in Adolescents and Young Adults: Clinical Aspects, Treatment Options and Unmet Medical Needs	27
Steroid Premedication and Monoclonal Antibody Therapy: Should We Reconsider?	27
Proposals for Clinical Trials in Chronic Myelomonocytic Leukemia	27
Gastric Cancer with Sarcopenia: an Area Worth Focusing On	26
A Comprehensive Review on the Role of Lurbinectedin in Soft Tissue Sarcomas	25
Circulating Tumor DNA in Diffuse Large B-Cell Lymphoma: from Bench to Bedside?	25
Recognition and Management of the Long-term Effects of Cranial Radiation	25
Review of Bone Metastasis in Gynecologic Malignancies: Evaluation and Treatment	24
Research Progress on Ferroptosis in Multiple Myeloma	24
Endocrinologic Toxicities of Cancer Therapy: Evolving Challenges and Multidisciplinary Approaches	24
Response Evaluation of Neoadjuvant Therapies in Sarcoma	23
R0 Resection in Recurrent Gynecologic Malignancy: Pelvic Exenteration and Beyond	23
Approach to Stereotactic Body Radiotherapy for the Treatment of Advanced Hepatocellular Carcinoma in Patients with Child-Pugh B-7 Cirrhosis	22
New Therapeutic Targets in RAS Wild-type Pancreatic Cancer	22
Therapeutic Challenges in the Management of Serous Endometrial Intraepithelial Carcinoma (SEIC)	21
Dyadic Interventions for LGBTQ+ Individuals Facing Cancer: A Narrative Review	21
Transforming a Roadblock into a Roadmap: Evolving HFSR Management From Adverse Event to Efficacy Biomarker	21
Emerging DNA Methylome Targets in FLT3-ITD-Positive Acute Myeloid Leukemia: Combination Therapy with Clinically Approved FLT3 Inhibitors	21
Evolution of Treatment Strategies for Gestational Trophoblastic Neoplasia: Chemotherapy, Immunotherapy, and Molecular Targeted Therapy	21
Application of Engineered Dendritic Cell Vaccines in Cancer Immunotherapy: Challenges and Opportunities	20
One Size Fits Some: Approaching Rare Malignancies of the Urinary Tract	20
Novel Estrogen Receptor-Targeted Agents for Breast Cancer	20
Neoadjuvant Photodynamic Therapy: An Updated Therapeutic Approach for Non-Melanoma Skin Cancers	20
Contemporary Review of Adenocarcinoma of the Cervix	20
Neoadjuvant and Adjuvant Therapy Approaches to Gastric Cancer	20
Treatment Options for Brain Metastases	20
Updates in Management of Malignant Pleural Mesothelioma	19
Progress in the Treatment of Small Intestine Cancer	19
Advancing Bladder Cancer Management: The Role of Neoadjuvant and Adjuvant Therapies and Biomarkers in Muscle Invasive Bladder Cancer	19
Understanding, Recognizing, and Managing Cancer-Related Fatigue Associated with Breast Cancer	19
New Developments in Systemic Management for High-Risk Early-Stage Hormone-Receptor-Positive, HER2-Negative Breast Cancer	19
Navigating PARP Inhibitor Resistance in Ovarian Cancer: Bridging Mechanistic Insights To Clinical Translation	19
What are the Optimal Systemic Treatment Options for Rhabdomyosarcoma?	19
Perioperative Immune Checkpoint Inhibitors for the Treatment of Locally Advanced Gastric and Gastroesophageal Junction Cancer: Current Status and Future Prospects	19
Updates in Breast Cancer Screening and Diagnosis	18
How Genetics Can Drive Initial Therapy Choices for Older Patients with Acute Myeloid Leukemia	18
Myxoid Liposarcomas: Systemic Treatment Options	17
New Insights into the Understanding of Mechanisms of Radiation-Induced Heart Disease	17
The Role of Induction Therapy for Sinonasal Cancers	17
Immunotherapy in the Treatment of Undifferentiated Pleomorphic Sarcoma and Myxofibrosarcoma	17
Advances in PSMA-Targeted Radionuclide Therapeutics	17
Treatment of Non-Small Cell Lung Cancer with Atypical EGFR Mutations	17
Perioperative Chemotherapy for Liver Metastasis of Colorectal Cancer: Lessons Learned and Future Perspectives	17
A Review on Integrating Breast Cancer Clinical Data: A Unified Platform Perspective	16
Optimal First-Line Therapy for Metastatic Adenocarcinoma of the Esophagus	16
Hypnosis for Symptom Management in Adult Cancer Patients: What is the Evidence?	16
New Developments in Treating RAS-Mutated Metastatic Colorectal Cancer	16
Correction to: Cardiotoxicity of Systemic Melanoma Treatments	16
“When Less is More”: Paradigm Shifts in Radiation Treatment for Early-Stage Breast Cancer	16

Targeting the Renin–angiotensin–aldosterone System (RAAS) for Cardiovascular Protection and Enhanced Oncological Outcomes: Review	15
Re-thinking the Role of Thoracic Radiotherapy in the First-Line Treatment for Extensive-Stage Small Cell Lung Cancer	15
The Role of SIRT1 in Leukemia	15
Taxane-Associated Acute Pain Syndrome: a Review of its Features and Management	15
Extent of Resection and Outcomes of Patients with Primary Malignant Brain Tumors	14
ctDNA to Guide Treatment of Colorectal Cancer: Ready for Standard of Care?	14
Metastatic Castration-Resistant Prostate Cancer: Advances in Treatment and Symptom Management	14
Immunotherapy for Metastatic Triple Negative Breast Cancer: Current Paradigm and Future Approaches	14
Therapeutic Management of Malignant Wounds: An Update	14
Enhancing Colorectal Cancer Treatment Through VEGF/VEGFR Inhibitors and Immunotherapy	14
Correction to: Recent Advances in Succinate Dehydrogenase Deficient Gastrointestinal Stromal Tumor Systemic Therapies	14
Management of Functional Pancreatic Neuroendocrine Neoplasms	14
Correction to: Voluntary Assisted Dying/Euthanasia: Will This Have an Impact on Cancer Care in Future Years?	14
Systemic Therapy for Salivary Gland Cancers: A Review of Targeted and Chemotherapeutic Approaches	13
RAS and Other Molecular Targets in Pancreatic Cancer: The Next Wave Is Coming	13
Innovations in Cardio-oncology Resulting from the COVID-19 Pandemic	13
Management and Treatment of Non-small Cell Lung Cancer with MET Alteration and Mechanisms of Resistance	13
Radiotherapy for Advanced Esophageal Cancer: from Palliation to Curation	13
Dermatofibrosarcoma Protuberans (DFSP): Diagnostics and Molecular Pathology	13
Advancements in Melanoma Therapies: From Surgery to Immunotherapy	13
Emerging Therapeutic Approaches to Pancreatic Adenocarcinoma: Advances and Future Directions	13
HER2-Positive Metastatic Colorectal Cancer	13
Osteogenic Sarcoma of the Head and Neck: Is Chemotherapy Needed?	13
Community Palliative Care: What are the Best Models?	12
Is There Still a Role for Transplant for Patients with Mantle Cell Lymphoma (MCL) in the Era of CAR-T Cell Therapy?	12
Measurable Residual Disease in Chronic Lymphocytic Leukemia: Current Understanding and Evolving Role in Clinical Practice	12
Integrating Systemic Therapies into the Multimodality Therapy of Patients with Craniopharyngioma	12
Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer	12
Correction to: Surgical Management and Considerations for Patients with Localized High-Risk Prostate Cancer	12
Diagnosis and Treatment of Myxoid Liposarcoma	12
Targeted Therapy in Early Stage Non-small Cell Lung Cancer	12
Neuroendocrine Tumors: Germline Genetics and Hereditary Syndromes	12
Impact of PSMA PET on Prostate Cancer Management	12
Nanomedicine-Based Treatments for Rare and Aggressive Ocular Cancers: Advances in Drug Delivery	12
The Improving Outcomes in Relapsed-Refractory Diffuse Large B Cell Lymphoma: The Role of CAR T-Cell Therapy	12
Current Surgical Management for Acral Melanoma	11
Prediction of Response to FDA-Approved Targeted Therapy and Immunotherapy in Acute Lymphoblastic Leukemia (ALL)	11
Central Nervous System Prophylaxis and Treatment in Acute Leukemias	11
Systemic and Targeted Therapies in Adenoid Cystic Carcinoma	11
The Role of Sentinel Lymph Node Mapping in High-grade Endometrial Cancer	11
Treatment of Relapsed Acute Lymphocytic Leukemia in Adult Patients	11
Antibody-Drug Conjugates in Gynecologic Cancers	11
Dermatofibrosarcoma Protuberans (DFSP): Current Treatments and Clinical Trials	11
Systemic Management of Advanced Adrenocortical Carcinoma	11
An Update on the Clinical Status, Challenges, and Future Directions of Oncolytic Virotherapy for Malignant Gliomas	11
Advanced Acral Melanoma Therapies: Current Status and Future Directions	11
The Evolving Landscape of Ovarian Cancer: Innovations in Biotechnology and Artificial Intelligence- Based Screening and Treatment	11
Neuropathic Pain in Cancer: What Are the Current Guidelines?	11
The Role of Pharmacogenomics in Opioid Prescribing	11
Management of Stage IVB Cervical Cancer Including the Role of Radiotherapy	11
The Role of Cetuximab in Non-Melanoma Skin Cancer: A Review of Clinical Evidence and Emerging Strategies	10
Contemporary Use of Hormonal Therapy in Endometrial Cancer: a Literature Review	10
Emerging Applications of CAR-T Cell Therapy in Overcoming Resistance and Expanding Targets in Hematologic Malignancies: Insights from Recent Research	10
Interventional Cardio-Oncology: Unique Challenges and Considerations in a High-Risk Population	10
Current Drug Resistance Mechanisms and Treatment Options in Gastrointestinal Stromal Tumors: Summary and Update	10
New Molecular Insights, and the Role of Systemic Therapies and Collaboration for Treatment of Epithelioid Hemangioendothelioma (EHE)	10
Central Nervous System Metastases in Breast Cancer	10
Relapsed Synovial Sarcoma: Treatment Options	10
Role of Geriatric Assessment in Hematopoietic Stem Cell Transplant and Cellular Therapies	10
Advances in Understanding Drug Resistance Mechanisms and Innovative Clinical Treatments for Melanoma	10
The Use of Targeted Therapy in Pediatric Acute Lymphoblastic Leukemia: Exploring Novel Approaches and Emerging Therapies	9
Immunotherapy in Early-Stage Triple-Negative Breast Cancer: Where Are We Now and Where Are We Headed?	9
Underlying Mechanisms of Thrombosis Associated with Cancer and Anticancer Therapies	9
Updates in Systemic Treatment of Hormone Receptor-Positive Early-Stage Breast Cancer	9
Current Standards, Multidisciplinary Approaches, and Future Directions in the Management of Extrahepatic Cholangiocarcinoma	9
A Comprehensive Review of Cancer Drug–Induced Cardiotoxicity in Blood Cancer Patients: Current Perspectives and Therapeutic Strategies	9
The Crying Need for a Better Response Assessment in Rectal Cancer	9
Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review	9
Candidate Biomarker of Response to Immunotherapy In Small Cell Lung Cancer	9
The Evolving Treatment Landscape of Merkel Cell Carcinoma	9
Covalent and Non-Covalent BTK Inhibition in Chronic Lymphocytic Leukemia Treatment	9
Skin Reactions and Other Underappreciated Dermatologic Side Effects of Cancer Therapies	9
Correction to: Metastatic Hormone–Sensitive Prostate Cancer in the Era of Doublet and Triplet Therapy	9
Secondary Central Nervous System Lymphoma: Updates in Treatment and Prophylaxis Strategies	9
Not All Leiomyosarcomas Are the Same: How to Best Classify LMS	9
New Immuno-oncology Targets and Resistance Mechanisms	9
Frontiers of Ovarian Carcinosarcoma	9
PAI-1 in Skin Malignancies: a Central Regulator of Tumor Progression and Therapeutic Resistance	9
Evolving Immunotherapy Strategies in Gastrointestinal Neuroendocrine Neoplasms	9
Updates on Therapy Options in Fit and Unfit Patients with Newly Diagnosed AML	8

Therapeutic Cancer Vaccines for Nonmelanoma Skin Cancer	8
Papillary Renal Cell Carcinoma: A Review of Prospective Clinical Trials	8
Addressing Sexual Health in Breast Cancer Survivors: Evidence-Based Practices and Clinical Considerations	8
Combination Immunotherapy for Mucosal Melanoma: Molecular Mechanism, Research Status, and Future Directions	8
Treatment of node-positive endometrial cancer: chemotherapy, radiation, immunotherapy, and targeted therapy	8
Angiosarcoma: Role of Immunotherapy	8
Tarlatamab-dlle: A New Hope for Patients with Extensive-Stage Small-Cell Lung Cancer	8
Desmoid Tumors: Current Perspective and Treatment	8
Surgery Matters: Progress in Surgical Management of Gastric Cancer	8
Advanced Mucosal Melanoma Therapies: Current Status and Future Directions	7
Updates in Hormone Replacement Therapy for Survivors of Gynecologic Cancers	7
Whole Lung Irradiation in Ewing Sarcoma with Pulmonary Metastases: Critical Appraisal of Evolution, Evidence, and Future Pathways in Precision Oncology	7
Research Progress on the Use of Metformin in Leukemia Treatment	7
Increasing Diversity in Head and Neck Cancer Clinical Trials	7
Neoadjuvant Short- Vs. Long-Course Radiation for Locally Advanced Rectal Cancer: How to Choose	7
Epithelioid Hemangioendothelioma: Treatment Landscape and Innovations for an Ultra-Rare Sarcoma	7
Targeted Therapies in the Treatment of Uterine Serous Carcinoma	7
Targeting Glutamine Metabolism as an Attractive Therapeutic Strategy for Acute Myeloid Leukemia	7
Targeted Therapy and Immunotherapy in Elderly Patients with Metastatic Colorectal Cancer	7
Metastatic HER2-Positive Breast Cancer: Is There an Optimal Sequence of Therapy?	7
Immunotherapy in HPV-Related Oropharyngeal Cancers	7
Systemic Anticancer Treatment Near the End of Life: a Narrative Literature Review	7
Incorporating Molecular Diagnostics into Treatment Paradigms for Endometrial Cancer	7
Pathogenic Mechanisms in Acute Myeloid Leukemia	7
Targeting the FGFR Pathway in Urothelial Carcinoma: the Future Is Now	7
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?	7
What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?	7
Intraperitoneal and Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Ovarian Cancer	6
Unlocking the Therapeutic Potential of Natural Polyphenols in Esophageal Cancer	6
Molecular Heterogeneity in Leiomyosarcoma and Implications for Personalised Medicine	6
Cardiovascular Considerations in Patients Undergoing Hematopoietic Cell Transplantation	6
Therapeutic and Supportive Effects of Cannabinoids in Patients with Brain Tumors (CBD Oil and Cannabis)	6
Cardio-oncology for Pediatric and Adolescent/Young Adult Patients	6
The Current Cardio-Oncology Landscape Across Australia	6
Systemic Therapy for Melanoma Brain and Leptomeningeal Metastases	6
Photodynamic application in diagnostic procedures and treatment of non-melanoma skin cancers	6
Small-Molecule Compounds Boost CAR-T Cell Therapy in Hematological Malignancies	6
Advances in Surgical Management of Malignant Tumors of the Distal Tibia	6
Respiratory Depression Associated with Opioids: A Narrative Review	6
Cardio-Oncology and Breast Cancer Therapies	6
Systemic Therapy for Solitary Fibrous Tumor	6
Neoadjuvant Chemotherapy for Adults with Osteogenic Sarcoma	6
Emerging Advances in the Molecular Landscape of Penile Cancer and Their Implications for Precision Medicine	6
Beyond Serous: Treatment Options for Rare Endometrial Cancers	6
The Role of Radiotherapy in the Management of Melanoma Brain Metastases: An Overview	6
Research Priorities and Future Directions in Cardio-Oncology	6
Oncofertility in the Age of HER2 Blockade, Immunotherapy, PARP inhibitors, CDK4/6 inhibitors and Endocrine Treatment: Unanswered Questions in Breast Cancer	6
Molecular Secrets Revealed: How Diabetes may be Paving the Way for Leukemia	6