Current Treatment Options in Oncology

Article	Citations
Role of Metastasis-Directed Therapy in Genitourinary Cancers	110
Correction to: Antibody–Drug Conjugate Revolution in Breast Cancer: The Road Ahead	77
Clinical Application of Artificial Intelligence for Non-melanoma Skin Cancer	75
Current Approaches of Immune Checkpoint Therapy in Chronic Lymphocytic Leukemia	74
Current Therapeutic Landscape in Lower Risk Myelodysplastic Syndromes	61
Advances in the Pathogenesis, Diagnosis, Treatment, and Prognosis of Marginal Zone Lymphoma	55
Selecting Optimal First-Line Treatment for Microsatellite Stable and Non-Mutated RAS/BRAF Metastatic Colorectal Cancer	55
An Update on Temporal Bone Paragangliomas	54
Antibody-Drug Conjugates for Melanoma and Other Skin Malignancies	53
The Future of Natural Killer Cell Immunotherapy for B Cell Non-Hodgkin Lymphoma (B Cell NHL)	45
“Off-the-Shelf” Allogeneic CAR Cell Therapy—Neglected HvG Effect	44
The Role of Nursing in the Delivery of Cardio-Oncology	44
Combining Radiotherapy with Immunotherapy in Cervical Cancer: Where Do We Stand and Where Are We Going?	39
HPV as a Carcinomic Driver in Head and Neck Cancer: a De-escalated Future?	39
Chronic Lymphocytic Leukemia: Chemotherapy Free and Other Novel Therapies Including CAR T	37
Depression and Long-Term Prescription Opioid Use and Opioid Use Disorder: Implications for Pain Management in Cancer	36
Management of Fatigue in Patients with Advanced Cancer	34
Options and Considerations in the Management of Peritoneal Disease in Patients with Small Bowel Neuroendocrine Tumors	34
Recent Advances in Liver Transplantation for Hepatocellular Carcinoma	33
Small Cell Lung Cancer—An Update on Chemotherapy Resistance	30
Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers	30
Where Are We Now and Where Might We Be Headed in Understanding and Managing Brain Metastases in Colorectal Cancer Patients?	29
Approach to Localized Squamous Cell Cancer of the Esophagus	29
Current Practice in Carcinoid Heart Disease and Burgeoning Opportunities	28
Perioperative Immunotherapy in Muscle-Invasive Bladder Cancer	28

Targets Selection for Precision Therapy of Relapsed/Refractory Multiple Myeloma: the Latest Advancements	28
Reshaping Treatment Paradigms for Advanced Renal Cell Cancer Patients and Improving Patient Management	26
Advances in Targeted Therapy for Metastatic Prostate Cancer	26
Regorafenib for the Treatment of Sarcoma	26
The Review of Modified Intersphincteric Resection in the Treatment of Ultra-Low Rectal Cancer	25
Revolutionizing Breast Cancer Therapeutics: Intersecting Frontiers of Precision Medicine, Nanotechnology, and Drug Delivery Innovations	25
Steroid Premedication and Monoclonal Antibody Therapy: Should We Reconsider?	24
New Treatment Options for Newly-Diagnosed and Relapsed Chronic Lymphocytic Leukemia	23
Proposals for Clinical Trials in Chronic Myelomonocytic Leukemia	23
Gastric Cancer with Sarcopenia: an Area Worth Focusing On	22
Novel Approaches for the Treatment of Patients with Richter’s Syndrome	22
Essential Thrombocythemia in Adolescents and Young Adults: Clinical Aspects, Treatment Options and Unmet Medical Needs	22
Circulating Tumor DNA in Diffuse Large B-Cell Lymphoma: from Bench to Bedside?	21
Correction to: The Microbiome: the Link to Colorectal Cancer and Research Opportunities	21
Optimal Strategies for Colorectal Cancer Screening	21
R0 Resection in Recurrent Gynecologic Malignancy: Pelvic Exenteration and Beyond	21
Recognition and Management of the Long-term Effects of Cranial Radiation	21
A Comprehensive Review on the Role of Lurbinectedin in Soft Tissue Sarcomas	21
Response Evaluation of Neoadjuvant Therapies in Sarcoma	21
Treatment Options for Brain Metastases	20
Emerging DNA Methylome Targets in FLT3-ITD-Positive Acute Myeloid Leukemia: Combination Therapy with Clinically Approved FLT3 Inhibitors	20
Evolution of Treatment Strategies for Gestational Trophoblastic Neoplasia: Chemotherapy, Immunotherapy, and Molecular Targeted Therapy	20
Contemporary Review of Adenocarcinoma of the Cervix	20
Neoadjuvant and Adjuvant Therapy Approaches to Gastric Cancer	19
Approach to Stereotactic Body Radiotherapy for the Treatment of Advanced Hepatocellular Carcinoma in Patients with Child-Pugh B-7 Cirrhosis	19
New Therapeutic Targets in RAS Wild-type Pancreatic Cancer	19
Review of Bone Metastasis in Gynecologic Malignancies: Evaluation and Treatment	19
Novel Estrogen Receptor-Targeted Agents for Breast Cancer	18
Application of Engineered Dendritic Cell Vaccines in Cancer Immunotherapy: Challenges and Opportunities	18
Current Trends in Precision Medicine and Next-Generation Sequencing in Head and Neck Cancer	18
Therapeutic Challenges in the Management of Serous Endometrial Intraepithelial Carcinoma (SEIC)	18
Dyadic Interventions for LGBTQ+ Individuals Facing Cancer: A Narrative Review	18
New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms	18
Progress in the Treatment of Small Intestine Cancer	17
Research Progress on Ferroptosis in Multiple Myeloma	17
Neoadjuvant Photodynamic Therapy: An Updated Therapeutic Approach for Non-Melanoma Skin Cancers	17
One Size Fits Some: Approaching Rare Malignancies of the Urinary Tract	17
Treating Chronic Pain with Buprenorphine—The Practical Guide	17
Navigating PARP Inhibitor Resistance in Ovarian Cancer: Bridging Mechanistic Insights To Clinical Translation	17
Promising Blood-Based Biomarkers for Melanoma: Recent Progress of Liquid Biopsy and Its Future Perspectives	17
New Developments in Systemic Management for High-Risk Early-Stage Hormone-Receptor-Positive, HER2-Negative Breast Cancer	16
The Dilemma of Treating Delirium: the Conundrum of Drug Management	16
Immunotherapy in the Treatment of Undifferentiated Pleomorphic Sarcoma and Myxofibrosarcoma	16
Updates in Management of Malignant Pleural Mesothelioma	16
How Genetics Can Drive Initial Therapy Choices for Older Patients with Acute Myeloid Leukemia	16
Perioperative Immune Checkpoint Inhibitors for the Treatment of Locally Advanced Gastric and Gastroesophageal Junction Cancer: Current Status and Future Prospects	16
What are the Optimal Systemic Treatment Options for Rhabdomyosarcoma?	16
A Review on Integrating Breast Cancer Clinical Data: A Unified Platform Perspective	15
New Insights into the Understanding of Mechanisms of Radiation-Induced Heart Disease	15
Treatment of Non-Small Cell Lung Cancer with Atypical EGFR Mutations	15

Updates in Breast Cancer Screening and Diagnosis	15
Enhancing Colorectal Cancer Treatment Through VEGF/VEGFR Inhibitors and Immunotherapy	15
Perioperative Chemotherapy for Liver Metastasis of Colorectal Cancer: Lessons Learned and Future Perspectives	15
Advancing Bladder Cancer Management: The Role of Neoadjuvant and Adjuvant Therapies and Biomarkers in Muscle Invasive Bladder Cancer	15
Correction to: Cardiotoxicity of Systemic Melanoma Treatments	14
Optimal First-Line Therapy for Metastatic Adenocarcinoma of the Esophagus	14
The Role of Induction Therapy for Sinonasal Cancers	14
New Developments in Treating RAS-Mutated Metastatic Colorectal Cancer	14
Advances in PSMA-Targeted Radionuclide Therapeutics	13
Re-thinking the Role of Thoracic Radiotherapy in the First-Line Treatment for Extensive-Stage Small Cell Lung Cancer	13
Taxane-Associated Acute Pain Syndrome: a Review of its Features and Management	13
Metastatic Castration-Resistant Prostate Cancer: Advances in Treatment and Symptom Management	13
Targeting the Renin–angiotensin–aldosterone System (RAAS) for Cardiovascular Protection and Enhanced Oncological Outcomes: Review	13
“When Less is More”: Paradigm Shifts in Radiation Treatment for Early-Stage Breast Cancer	12
Management and Treatment of Non-small Cell Lung Cancer with MET Alteration and Mechanisms of Resistance	12
Extent of Resection and Outcomes of Patients with Primary Malignant Brain Tumors	12
Therapeutic Management of Malignant Wounds: An Update	12
Myxoid Liposarcomas: Systemic Treatment Options	12
Hypnosis for Symptom Management in Adult Cancer Patients: What is the Evidence?	12
Correction to: Voluntary Assisted Dying/Euthanasia: Will This Have an Impact on Cancer Care in Future Years?	12
RAS and Other Molecular Targets in Pancreatic Cancer: The Next Wave Is Coming	12
Correction to: Recent Advances in Succinate Dehydrogenase Deficient Gastrointestinal Stromal Tumor Systemic Therapies	12
The Role of SIRT1 in Leukemia	12
Complex Persistent Opioid Dependence—an Opioid-induced Chronic Pain Syndrome	12
HER2-Positive Metastatic Colorectal Cancer	12
Advancements in Melanoma Therapies: From Surgery to Immunotherapy	12
ctDNA to Guide Treatment of Colorectal Cancer: Ready for Standard of Care?	12
Management of Functional Pancreatic Neuroendocrine Neoplasms	11
The Use of Targeted Agents in the Treatment of Gynecologic Cancers	11
Correction to: Surgical Management and Considerations for Patients with Localized High-Risk Prostate Cancer	11
Neuroendocrine Tumors: Germline Genetics and Hereditary Syndromes	11
Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer	11
Immunotherapy for Metastatic Triple Negative Breast Cancer: Current Paradigm and Future Approaches	11
Radiotherapy for Advanced Esophageal Cancer: from Palliation to Curation	11
Osteogenic Sarcoma of the Head and Neck: Is Chemotherapy Needed?	11
Innovations in Cardio-oncology Resulting from the COVID-19 Pandemic	11
Dermatofibrosarcoma Protuberans (DFSP): Diagnostics and Molecular Pathology	11
The Role of Pharmacogenomics in Opioid Prescribing	11
Emerging Therapeutic Approaches to Pancreatic Adenocarcinoma: Advances and Future Directions	11
The Improving Outcomes in Relapsed-Refractory Diffuse Large B Cell Lymphoma: The Role of CAR T-Cell Therapy	11
Integrating Systemic Therapies into the Multimodality Therapy of Patients with Craniopharyngioma	11
Systemic Management of Advanced Adrenocortical Carcinoma	10
Is There Still a Role for Transplant for Patients with Mantle Cell Lymphoma (MCL) in the Era of CAR-T Cell Therapy?	10
Measurable Residual Disease in Chronic Lymphocytic Leukemia: Current Understanding and Evolving Role in Clinical Practice	10
Impact of PSMA PET on Prostate Cancer Management	10
The Evolving Landscape of Ovarian Cancer: Innovations in Biotechnology and Artificial Intelligence- Based Screening and Treatment	10
Cardio-Oncology Care Delivered in the Non-academic Environment	10
Nanomedicine-Based Treatments for Rare and Aggressive Ocular Cancers: Advances in Drug Delivery	10
What Clinical Trials Are Needed for Treatment of Leiomyosarcoma?	10
Systemic and Targeted Therapies in Adenoid Cystic Carcinoma	10
Current WHO Guidelines and the Critical Role of Genetic Parameters in the Classification of Glioma: Opportunities for Immunotherapy	10
An Update on the Clinical Status, Challenges, and Future Directions of Oncolytic Virotherapy for Malignant Gliomas	10
Targeted Therapy in Early Stage Non-small Cell Lung Cancer	10
Community Palliative Care: What are the Best Models?	10
Diagnosis and Treatment of Myxoid Liposarcoma	10
Treatment of Relapsed Acute Lymphocytic Leukemia in Adult Patients	10
Management of Stage IVB Cervical Cancer Including the Role of Radiotherapy	10
Advanced Acral Melanoma Therapies: Current Status and Future Directions	9
Current Surgical Management for Acral Melanoma	9
Management of Cutaneous Angiosarcoma: an Update Review	9
New Molecular Insights, and the Role of Systemic Therapies and Collaboration for Treatment of Epithelioid Hemangioendothelioma (EHE)	9
Advances in Understanding Drug Resistance Mechanisms and Innovative Clinical Treatments for Melanoma	9
Dermatofibrosarcoma Protuberans (DFSP): Current Treatments and Clinical Trials	9
The Role of Sentinel Lymph Node Mapping in High-grade Endometrial Cancer	9
Antibody-Drug Conjugates in Gynecologic Cancers	9
Interventional Cardio-Oncology: Unique Challenges and Considerations in a High-Risk Population	9
Current Drug Resistance Mechanisms and Treatment Options in Gastrointestinal Stromal Tumors: Summary and Update	9
Contemporary Use of Hormonal Therapy in Endometrial Cancer: a Literature Review	9
Central Nervous System Prophylaxis and Treatment in Acute Leukemias	9
Prediction of Response to FDA-Approved Targeted Therapy and Immunotherapy in Acute Lymphoblastic Leukemia (ALL)	9
Radiation and Chimeric Antigen Receptor T-cell Therapy in B-cell Non-Hodgkin Lymphomas	9
Induction Chemotherapy in Low-Risk HPV+ Oropharyngeal Cancer	9
The Role of Cetuximab in Non-Melanoma Skin Cancer: A Review of Clinical Evidence and Emerging Strategies	9
Role of Geriatric Assessment in Hematopoietic Stem Cell Transplant and Cellular Therapies	9
Neuropathic Pain in Cancer: What Are the Current Guidelines?	9
Correction to: Metastatic Hormone–Sensitive Prostate Cancer in the Era of Doublet and Triplet Therapy	8
The Microbiome: the Link to Colorectal Cancer and Research Opportunities	8
Gastrointestinal Stromal Tumors: What Is the Best Sequence of TKIs?	8
The Crying Need for a Better Response Assessment in Rectal Cancer	8
Underlying Mechanisms of Thrombosis Associated with Cancer and Anticancer Therapies	8

Frontiers of Ovarian Carcinosarcoma	8
The Evolving Treatment Landscape of Merkel Cell Carcinoma	8
Relapsed Synovial Sarcoma: Treatment Options	8
Central Nervous System Metastases in Breast Cancer	8
Secondary Central Nervous System Lymphoma: Updates in Treatment and Prophylaxis Strategies	8
Systemic Therapy in Advanced Pleomorphic Liposarcoma: a Comprehensive Review	8
New Immuno-oncology Targets and Resistance Mechanisms	8
Skin Reactions and Other Underappreciated Dermatologic Side Effects of Cancer Therapies	8
Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence	8
Evolving Immunotherapy Strategies in Gastrointestinal Neuroendocrine Neoplasms	8
Candidate Biomarker of Response to Immunotherapy In Small Cell Lung Cancer	8
Immunotherapy in Early-Stage Triple-Negative Breast Cancer: Where Are We Now and Where Are We Headed?	8
A Comprehensive Review of Cancer Drug–Induced Cardiotoxicity in Blood Cancer Patients: Current Perspectives and Therapeutic Strategies	8
Not All Leiomyosarcomas Are the Same: How to Best Classify LMS	8
Dermatofibrosarcoma Protuberans in Children	7
Papillary Renal Cell Carcinoma: A Review of Prospective Clinical Trials	7
Neoadjuvant Short- Vs. Long-Course Radiation for Locally Advanced Rectal Cancer: How to Choose	7
Therapeutic Cancer Vaccines for Nonmelanoma Skin Cancer	7
Current Standards, Multidisciplinary Approaches, and Future Directions in the Management of Extrahepatic Cholangiocarcinoma	7
Covalent and Non-Covalent BTK Inhibition in Chronic Lymphocytic Leukemia Treatment	7
Addressing Sexual Health in Breast Cancer Survivors: Evidence-Based Practices and Clinical Considerations	7
Updates in Systemic Treatment of Hormone Receptor-Positive Early-Stage Breast Cancer	7
Incorporating Molecular Diagnostics into Treatment Paradigms for Endometrial Cancer	7
Targeting Glutamine Metabolism as an Attractive Therapeutic Strategy for Acute Myeloid Leukemia	7
Desmoid Tumors: Current Perspective and Treatment	7
Updates in Hormone Replacement Therapy for Survivors of Gynecologic Cancers	7
PAI-1 in Skin Malignancies: a Central Regulator of Tumor Progression and Therapeutic Resistance	7
Updates on Therapy Options in Fit and Unfit Patients with Newly Diagnosed AML	7
The Evolving Neoadjuvant Treatment Paradigm for Patients with Locoregional mismatch Repair Proficient Rectal Cancer	7
Tarlatamab-dlle: A New Hope for Patients with Extensive-Stage Small-Cell Lung Cancer	7
Treatment of node-positive endometrial cancer: chemotherapy, radiation, immunotherapy, and targeted therapy	7
Surgery Matters: Progress in Surgical Management of Gastric Cancer	7
Who Should Receive Immunotherapy for Advanced Gastroesophageal Cancer?	7
Epithelioid Hemangioendothelioma: Treatment Landscape and Innovations for an Ultra-Rare Sarcoma	7
Angiosarcoma: Role of Immunotherapy	7
COVID-19 and Gynecologic Oncology: What Have We Learned?	7
Combination Immunotherapy for Mucosal Melanoma: Molecular Mechanism, Research Status, and Future Directions	7
Natural Killer Cells: the Missing Link in Effective Treatment for High-Grade Serous Ovarian Carcinoma	7
Pathogenic Mechanisms in Acute Myeloid Leukemia	6
State of the Art in Endoscopic Therapy for the Management of Gastroenteropancreatic Neuroendocrine Tumors	6
Systemic Anticancer Treatment Near the End of Life: a Narrative Literature Review	6
High-Dose Somatostatin Analogs for the Treatment of Neuroendocrine Neoplasms: where are we Now?	6
Neoadjuvant Chemotherapy for Adults with Osteogenic Sarcoma	6
Targeting the FGFR Pathway in Urothelial Carcinoma: the Future Is Now	6
Metastatic HER2-Positive Breast Cancer: Is There an Optimal Sequence of Therapy?	6
Immune Checkpoint Inhibitors for the Treatment of Gestational Trophoblastic Neoplasia: Rationale, Effectiveness, and Future Fertility	6
Targeted Therapy and Immunotherapy in Elderly Patients with Metastatic Colorectal Cancer	6
Immunotherapy in Small Cell Lung Cancer Treatment: a Promising Headway for Future Perspective	6
Correction to: Cancer-Related Fatigue: Causes and Current Treatment Options	6
How the COVID-19 Pandemic Reshaped the Management of Leukemia and Affected Patient Outcomes	6
Molecular Secrets Revealed: How Diabetes may be Paving the Way for Leukemia	6
Immunotherapy in HPV-Related Oropharyngeal Cancers	6
Cardio-oncology for Pediatric and Adolescent/Young Adult Patients	6
Targeted Therapies in the Treatment of Uterine Serous Carcinoma	6
In Utero Development and Immunosurveillance of B Cell Acute Lymphoblastic Leukemia	6
Research Progress on the Use of Metformin in Leukemia Treatment	6
What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?	6
Intraperitoneal and Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Ovarian Cancer	5
Treatment Strategies for Malignancies of the External Auditory Canal	5
Therapeutic and Supportive Effects of Cannabinoids in Patients with Brain Tumors (CBD Oil and Cannabis)	5
Unlocking the Therapeutic Potential of Natural Polyphenols in Esophageal Cancer	5
CDK4/6 Inhibition in the Metastatic Setting: Where Are We Headed?	5
Current Treatment Options for Cutaneous Adnexal Malignancies	5
Emerging Advances in the Molecular Landscape of Penile Cancer and Their Implications for Precision Medicine	5
The Role of Radiotherapy in the Management of Melanoma Brain Metastases: An Overview	5
Respiratory Depression Associated with Opioids: A Narrative Review	5
Surgery in Patients with Gastro-Entero-Pancreatic Neuroendocrine Carcinomas, Neuroendocrine Tumors G3 and High Grade Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms	5
Small-Molecule Compounds Boost CAR-T Cell Therapy in Hematological Malignancies	5
Antiepileptic Strategies for Patients with Primary and Metastatic Brain Tumors	5
Do Patients Benefit from a Trial of Corticosteroids at the End of Life?	5
Photodynamic application in diagnostic procedures and treatment of non-melanoma skin cancers	5
Advances in the Treatment of Hairy Cell Leukemia Variant	5
Cardio-Oncology and Breast Cancer Therapies	5
Role of Radiotherapy in PCNSL within the Current Therapeutic Landscape: a Comprehensive Review	5
Molecular Heterogeneity in Leiomyosarcoma and Implications for Personalised Medicine	5
Beyond Serous: Treatment Options for Rare Endometrial Cancers	5
Cardiovascular Considerations in Patients Undergoing Hematopoietic Cell Transplantation	5