Current Treatment Options in Oncology

Article	Citations
Treatment of Relapsed Acute Myeloid Leukemia	135
Targeted Therapies in Advanced Gastric Cancer	125
Tumor Treating Fields in the Management of Patients with Malignant Gliomas	46
Metabolic Aspects of Anthracycline Cardiotoxicity	45
Emerging Treatments for Advanced/Metastatic Pheochromocytoma and Paraganglioma	42
Models of Integration of Specialized Palliative Care with Oncology	39
Advances in the Treatment of Cardiac Amyloidosis	36
The Effect of Prognostic Communication on Patient Outcomes in Palliative Cancer Care: a Systematic Review	35
Mycosis Fungoides and Sézary Syndrome: Updates and Review of Current Therapy	34
Systemic Therapy for Metastatic Pancreatic Cancer	33
The Importance of Prognostication: Impact of Prognostic Predictions, Disclosures, Awareness, and Acceptance on Patient Outcomes	33
Revolutions in treatment options in gastrointestinal stromal tumours (GISTs): the latest updates	33
Management of Non-small Cell Lung Cancer Patients with MET Exon 14 Skipping Mutations	30
When to Integrate Palliative Care in the Trajectory of Cancer Care	29
Optimal Strategies for Colorectal Cancer Screening	27
New Treatment Options for Advanced Biliary Tract Cancer	27
Immunotherapy in Hepatocellular Carcinoma	25
Neoadjuvant Therapy for Non-melanoma Skin Cancer: Updated Therapeutic Approaches for Basal, Squamous, and Merkel Cell Carcinoma	25
Leptomeningeal Metastases in Non-small Cell Lung Cancer: Optimal Systemic Management in NSCLC With and Without Driver Mutations	25
PI3K Inhibitors and Their Role as Novel Agents for Targeted Therapy in Lymphoma	25
Defining and Targeting BRAF Mutations in Solid Tumors	25
Biology and Treatment Paradigms in T Cell Acute Lymphoblastic Leukemia in Older Adolescents and Adults	24
Biomarkers of Immune Checkpoint Blockade Response in Triple-Negative Breast Cancer	24
Contemporary Management of Anaplastic Thyroid Cancer	22
Understanding and Supporting Informal Cancer Caregivers	22

Optimal Management of Corticosteroids in Patients with Intracranial Malignancies	22
Current Treatment of Melanoma Brain Metastasis	22
New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms	21
Systemic Therapy of Extensive Stage Small Cell Lung Cancer in the Era of Immunotherapy	21
BRAF Heterogeneity in Melanoma	21
Neoadjuvant and Adjuvant Therapy Approaches to Gastric Cancer	20
Cancer Treatment–Induced Bone Loss (CTIBL): State of the Art and Proper Management in Breast Cancer Patients on Endocrine Therapy	20
Cardiovascular Toxicities of Androgen Deprivation Therapy	20
Updates in the Treatment of Chemotherapy-Induced Peripheral Neuropathy	20
Current Management of Angiosarcoma: Recent Advances and Lessons From the Past	20
Radiation Necrosis from Stereotactic Radiosurgery—How Do We Mitigate?	19
Immunotherapy Alone or in Combination with Chemotherapy as First-Line Treatment of Non-Small Cell Lung Cancer	19
BRAF Inhibitor Resistance in Melanoma: Mechanisms and Alternative Therapeutic Strategies	19
Janus Kinase Inhibitors and Non-Melanoma Skin Cancer	19
Role of (Neo)adjuvant Denosumab for Giant Cell Tumor of Bone	18
The Biology of Synovial Sarcoma: State-of-the-Art and Future Perspectives	18
Systemic Options for Malignant Peripheral Nerve Sheath Tumors	17
Systemic Treatment of Gastroenteropancreatic Neuroendocrine Carcinoma	17
Beyond Microsatellite Instability: Evolving Strategies Integrating Immunotherapy for Microsatellite Stable Colorectal Cancer	17
Constipation in Cancer Patients — an Update of Clinical Evidence	16
Progress on Management of Penile Cancer in 2020	16
Re-evaluation of Sentinel Lymph Node Biopsy for Melanoma	16
Bispecific Antibodies for Non-Hodgkin Lymphoma Treatment	16
Evaluation and Management of Sleep and Circadian Rhythm Disturbance in Cancer	16
Appropriate Selection of PARP Inhibitors in Ovarian Cancer	16
Role of TKI for Metastatic Osteogenic Sarcoma	15
The Evolving Landscape of HER2-Directed Breast Cancer Therapy	15
Immunotherapy for Metastatic Triple Negative Breast Cancer: Current Paradigm and Future Approaches	15
Current Status of CAR T Cell Therapy for Leukemias	15
Role of Laser Interstitial Thermal Therapy in the Management of Primary and Metastatic Brain Tumors	15
Liquid Biopsy in Gastrointestinal Stromal Tumors: Ready for Prime Time?	15
Medical Cannabis in Oncology: a Valuable Unappreciated Remedy or an Undesirable Risk?	15
Cardiotoxicity of Radiation Therapy: Mechanisms, Management, and Mitigation	15
Small Round Blue Cell Sarcoma Other Than Ewing Sarcoma: What Should an Oncologist Know?	14
Late and Long-Term Treatment-Related Effects and Survivorship for Head and Neck Cancer Patients	14
The Potential of Immune Checkpoint Blockade in Cervical Cancer: Can Combinatorial Regimens Maximize Response? A Review of the Literature	14
Long Non-coding RNAs in Cisplatin Resistance in Osteosarcoma	14
The Benefits of Olanzapine in Palliating Symptoms	14
Surgical Principles in the Management of Pancreatic Neuroendocrine Neoplasms	14
Leveraging Social Media for Cardio-Oncology	13
Symptom Management in Pancreatic Cancer	13
Localized Non-melanoma Skin Cancer: Risk Factors of Post-surgical Relapse and Role of Postoperative Radiotherapy	13
Immunotherapy and Biomarkers in Sarcoma	13
Surgery in Patients with Gastro-Entero-Pancreatic Neuroendocrine Carcinomas, Neuroendocrine Tumors G3 and High Grade Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms	13
Family Meetings in Palliative Care: Benefits and Barriers	13
Immunosuppression in Medulloblastoma: Insights into Cancer Immunity and Immunotherapy	13
Biomarkers in Neuroblastoma: An Insight into Their Potential Diagnostic and Prognostic Utilities	12
TRK Inhibitors in Non-Small Cell Lung Cancer	12
Treatment for Oral Mucositis—Current Options and an Update of Small Molecules Under Development	12
Optimal Management for Residual Disease Following Neoadjuvant Systemic Therapy	12

Immunotherapy in Gastroesophageal Cancers: Current Evidence and Ongoing Trials	12
HER2-Directed Therapy in Advanced Gastric and Gastroesophageal Adenocarcinoma: Triumphs and Troubles	12
Robotic Surgery in Rectal Cancer: Potential, Challenges, and Opportunities	12
New Approaches to Myelodysplastic Syndrome Treatment	12
Hepatocellular Carcinoma: a Narrative Review on Current Knowledge and Future Prospects	12
Pathogenesis and Amelioration of Radiation-Induced Oral Mucositis	12
Systemic Therapy for Lung Cancer Brain Metastases	12
Treatment Strategies for Oligometastatic Breast Cancer	12
Treating Chronic Pain with Buprenorphine—The Practical Guide	12
Refining Immuno-Oncology Approaches in Metastatic Prostate Cancer: Transcending Current Limitations	12
Cancer or COVID-19? A Review of Recommendations for COVID-19 Vaccination in Cancer Patients	12
Update on First-Line Combination Treatment Approaches in Metastatic Clear-Cell Renal Cell Carcinoma	12
Exercise Training for Cancer Survivors	11
New Strategies and Novel Combinations in EGFR TKI-Resistant Non-small Cell Lung Cancer	11
Where Are We Now and Where Might We Be Headed in Understanding and Managing Brain Metastases in Colorectal Cancer Patients?	11
Proteomic and Metabolomic Profiling in Soft Tissue Sarcomas	11
BCL-2 Inhibition as Treatment for Chronic Lymphocytic Leukemia	11
Management of Laryngeal Dysplasia and Early Invasive Cancer	11
Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy	11
Strategies to Prevent Cardiotoxicity	11
Stereotactic Ablative Radiotherapy for Recurrent or Metastatic Gynecological Cancer: Extending Lives?	11
Surgical Management of Skull Base and Spine Chordomas	10
Interventional Liver-Directed Therapy for Neuroendocrine Metastases: Current Status and Future Directions	10
Treatment Approach to Adenocarcinoma of the Ampulla of Vater	10
New Treatment Strategies for the Inflammatory Breast Cancer	10
Targeting the FGFR Pathway in Urothelial Carcinoma: the Future Is Now	10
Hereditary Syndromes in Neuroendocrine Tumors	10
Approach to Localized Squamous Cell Cancer of the Esophagus	10
Nectin-4: a Novel Therapeutic Target for Skin Cancers	10
Treatment personalization in gastrointestinal neuroendocrine tumors	10
Recent and Emerging Therapies for Cutaneous Squamous Cell Carcinomas of the Head and Neck	10
Metastatic Adenoid Cystic Carcinoma: Genomic Landscape and Emerging Treatments	10
Use of Liquid Biopsy in the Care of Patients with Non-Small Cell Lung Cancer	10
The Role of Oncoplastic Surgery for Breast Cancer	10
HER2-Low Breast Cancer: a New Subtype?	10
New Treatment Options for Older Patients with Acute Myeloid Leukemia	10
How to Sequence Therapies in Diffuse Large B-Cell Lymphoma Post-CAR-T Cell Failure	10
Drug Repurposing in Medulloblastoma: Challenges and Recommendations	10
New Immuno-oncology Targets and Resistance Mechanisms	9
Advanced Acral Melanoma Therapies: Current Status and Future Directions	9
Defining and Treating Borderline Resectable Pancreatic Cancer	9
Allogeneic Chimeric Antigen Receptor Therapy in Lymphoma	9
Anatomic and Functional Imaging of Neuroendocrine Tumors	9
A Review of Pharmacologic Management in the Treatment of Mesothelioma	9
Defining Which Patients Are at High Risk for Recurrence of Soft Tissue Sarcoma	9
Cardiovascular Issues in Hematopoietic Stem Cell Transplantation (HSCT)	9
Current Challenge: Endoscopic Submucosal Dissection of Superficial Non-ampullary Duodenal Epithelial Tumors	9
Promising Blood-Based Biomarkers for Melanoma: Recent Progress of Liquid Biopsy and Its Future Perspectives	8
Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers	8
Drug Development in Neuroendocrine Tumors: What Is on the Horizon?	8
Management of Myelofibrosis: from Diagnosis to New Target Therapies	8
Perioperative Chemotherapy for Liver Metastasis of Colorectal Cancer: Lessons Learned and Future Perspectives	8
Contemporary Use of Hormonal Therapy in Endometrial Cancer: a Literature Review	8
Recurrent Treatment in Ovarian Cancer Patients: What Are the Best Regimens and the Order They Should Be Given?	8
Development of a Patient-Centered Framework for Oncology Clinicians to Address Uncertainty in Cancer Care During the COVID-19 Pandemic	8
Options for the Treatment of Mucinous Ovarian Carcinoma	8
Molecular-Driven Therapy in Advanced Thyroid Cancer	8
Integrating Palliative Care into Oncology Care Worldwide: The Right Care in the Right Place at the Right Time	8
Human Colon Organoids and Other Laboratory Strategies to Enhance Patient Treatment Selection	8
Immunotherapy in Small Cell Lung Cancer Treatment: a Promising Headway for Future Perspective	8
The Evolving Role of Consensus Molecular Subtypes: a Step Beyond Inpatient Selection for Treatment of Colorectal Cancer	8
Targeted Therapy for Melanomas Without BRAF V600 Mutations	8
Therapeutic Advances in the Management of Patients with Advanced RET Fusion-Positive Non-Small Cell Lung Cancer	8
Neoadjuvant Chemoimmunotherapy in Patients with Resectable Non-small Cell Lung Cancer	8
Small-Molecule Compounds Boost CAR-T Cell Therapy in Hematological Malignancies	7
Current Treatment Options for Older Patients with Hodgkin Lymphoma	7
Management of Cutaneous Angiosarcoma: an Update Review	7
Immunotherapy in HPV-Related Oropharyngeal Cancers	7
The Role of Epithelial-to-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma	7
HPV as a Carcinomic Driver in Head and Neck Cancer: a De-escalated Future?	7
Tailoring Treatment for Patients with Inflammatory Breast Cancer	7
Immune Checkpoint Inhibitor Rechallenge After Prior Immune Toxicity	7
Health-Related Quality of Life and Patient-Reported Outcomes in Radiation Oncology Clinical Trials	7
Myxoid Liposarcoma: How to Stage and Follow	7
The Role of Sentinel Lymph Node Mapping in High-grade Endometrial Cancer	7
Immune Checkpoint Inhibitors for the Treatment of Gestational Trophoblastic Neoplasia: Rationale, Effectiveness, and Future Fertility	7
Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer	7
Biology and Treatment of Hairy Cell Leukemia	7
Complex Persistent Opioid Dependence—an Opioid-induced Chronic Pain Syndrome	7
Natural Killer Cells: the Missing Link in Effective Treatment for High-Grade Serous Ovarian Carcinoma	7

New Insights into the Understanding of Mechanisms of Radiation-Induced Heart Disease	7
Cardiovascular Toxicities of Bruton’s Tyrosine Kinase Inhibitors	7
Circulating Biomarkers for Cardiotoxicity Risk Prediction	7
The Role of Pharmacogenomics in Opioid Prescribing	7
Postoperative Management of Salivary Gland Tumors	7
The Importance of Primary Care in Cardio-Oncology	7
Clinical Development of PD-1/PD-L1 Inhibitors in Breast Cancer: Still a Long Way to Go	7
Consolidation Therapy in Primary Central Nervous System Lymphoma	6
Cancer Therapies and Vascular Toxicities	6
Therapeutic and Supportive Effects of Cannabinoids in Patients with Brain Tumors (CBD Oil and Cannabis)	6
Surveillance and Monitoring Techniques for HPV-Related Head and Neck Squamous Cell Carcinoma: Circulating Tumor DNA	6
Approach to Resectable Biliary Cancers	6
Antiproliferative Systemic Therapies for Metastatic Small Bowel Neuroendocrine Tumours	6
Systemic Therapy for Chondrosarcoma	6
State of the Art in Endoscopic Therapy for the Management of Gastroenteropancreatic Neuroendocrine Tumors	6
Does Cannabidiol Have a Benefit as a Supportive Care Drug in Cancer?	6
Depression and Long-Term Prescription Opioid Use and Opioid Use Disorder: Implications for Pain Management in Cancer	6
Cancer Immunotherapy: Fecal Microbiota Transplantation Brings Light	6
Reirradiation of Recurrent and Second Primary Cancers of the Head and Neck: a Review of the Contemporary Evidence	6
Novel Biological Insights and New Developments in Management of Burkitt Lymphoma and High-Grade B-Cell Lymphoma	6
The Role of Radiation Therapy for Symptomatic Desmoid Tumors	6
Adjuvant Immunotherapy in Patients with Early-Stage Non-small Cell Lung Cancer and Future Directions	6
Systemic Therapy for Gastrointestinal Stromal Tumor: Current Standards and Emerging Challenges	6
Systemic and Targeted Therapies in Adenoid Cystic Carcinoma	6
Radical Hysterectomy for Cervical Cancer: the Right Surgical Approach	6
The Role of Biomarkers to Evaluate Cardiotoxicity	6
Dermatofibrosarcoma Protuberans in Children	6
Novel Therapies in the Treatment of Hodgkin Lymphoma	6
Progress in the Treatment of Small Intestine Cancer	6
Personalizing the Setting of Palliative Care Delivery for Patients with Advanced Cancer: “Care Anywhere, Anytime”	6
Antibody–Drug Conjugate Revolution in Breast Cancer: The Road Ahead	6
Surgical Principles in the Management of Small Bowel Neuroendocrine Tumors	6
Current WHO Guidelines and the Critical Role of Genetic Parameters in the Classification of Glioma: Opportunities for Immunotherapy	6
What Clinical Trials Are Needed for Treatment of Leiomyosarcoma?	6
Enhanced Photodynamic Therapy by Improved Light Energy Capture Efficiency of Porphyrin Photosensitizers	6
Novel Therapies for Follicular Lymphoma and Other Indolent Non-Hodgkin Lymphomas	6
Lessons Learned in Managing Patients with Colorectal Cancer During the COVID-19 Pandemic	5
Available Therapies for Patients with Neurofibromatosis-Related Nervous System Tumors	5
Secondary Central Nervous System Lymphoma: Updates in Treatment and Prophylaxis Strategies	5
Approach to the Patient with Unknown Primary Squamous Cell Carcinoma of the Head and Neck	5
Current Management and Treatment of Extramammary Paget’s Disease	5
Thrombosis in Acute Myeloid Leukemia: Pathogenesis, Risk Factors and Therapeutic Challenges	5
Hypomethylating Agents in Lymphoma	5
Management of Fatigue in Patients with Advanced Cancer	5
Use of Robotics in Surgical Treatment of Non-small Cell Lung Cancer	5
The Current Landscape of Research Advocacy and Education for Patients with Colorectal Cancer	5
Immunotherapy in Early-Stage Triple-Negative Breast Cancer: Where Are We Now and Where Are We Headed?	5
New Molecular Insights, and the Role of Systemic Therapies and Collaboration for Treatment of Epithelioid Hemangioendothelioma (EHE)	5
Gastrointestinal Stromal Tumors: What Is the Best Sequence of TKIs?	5
Novel Approaches for the Treatment of Patients with Richter’s Syndrome	5
Which FLT3 Inhibitor for Treatment of AML?	5
Targeting DNA Damage Repair Pathways in Pancreatic Adenocarcinoma	5
How to Sequence Therapies in Waldenström Macroglobulinemia	5
Should Loss of Appetite Be Palliated in Patients with Advanced Cancer?	5
Targeting KRASp.G12C Mutation in Advanced Non-Small Cell Lung Cancer: a New Era Has Begun	5
Molecular Determinants and Other Factors to Guide Selection of Patients for Hepatic Resection of Metastatic Colorectal Cancer	5
An Update on the Management of Mixed Neuroendocrine-Non-neuroendocrine Neoplasms (MiNEN)	5
Pulmonary Neuroendocrine Tumors: Adjuvant and Systemic Treatments	5
Acute Myeloid Leukemia Mutations and Future Mechanistic Target to Overcome Resistance	5
Management of Functional Pancreatic Neuroendocrine Neoplasms	5
Modulating Tumor Microenvironment: A Review on STK11 Immune Properties and Predictive vs Prognostic Role for Non-small-cell Lung Cancer Immunotherapy	5
Targeted Therapy for BRAF Mutant Brain Tumors	4
Radical Hysterectomy After the LACC Trial: Back to Radical Vaginal Surgery	4
The Evolving Neoadjuvant Treatment Paradigm for Patients with Locoregional mismatch Repair Proficient Rectal Cancer	4
Autophagy Paradox: Strategizing Treatment Modality in Melanoma	4
Indications for Allogeneic HCT in Adults with Acute Lymphoblastic Leukemia in First Complete Remission	4
Current Trends in Precision Medicine and Next-Generation Sequencing in Head and Neck Cancer	4
The Role of Laparoscopic Surgery in Localized Pancreatic Neuroendocrine Tumours	4
New Treatment Options for Newly-Diagnosed and Relapsed Chronic Lymphocytic Leukemia	4
Pathogenic Mechanisms in Acute Myeloid Leukemia	4
Translating Knowledge About the Immune Microenvironment of Gastrointestinal Stromal Tumors into Effective Clinical Strategies	4
Surgery Matters: Progress in Surgical Management of Gastric Cancer	4
ctDNA to Guide Treatment of Colorectal Cancer: Ready for Standard of Care?	4
Approach to Resectable Gastric Cancer: Evolving Paradigm of Neoadjuvant and Adjuvant Treatment	4
Multidisciplinary Management of Brain Metastases from Non-Small Cell Lung Cancer in the Era of Immunotherapy	4
Available Systemic Treatments and Emerging Therapies for Breast Cancer Brain Metastases	4
How Genetics Can Drive Initial Therapy Choices for Older Patients with Acute Myeloid Leukemia	4
The Future of Natural Killer Cell Immunotherapy for B Cell Non-Hodgkin Lymphoma (B Cell NHL)	4
Treatment Strategies for Malignancies of the External Auditory Canal	4
Cardio-oncology Training in the COVID-19 Era	4
Advances in Organ Preservation for Laryngeal Cancer	4
Selection of Oral Therapeutics in China for the Treatment of Colorectal Cancer	4
Future Strategies Involving Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma	4
Insights into the Use of Peripherally Acting μ-Opioid Receptor Antagonists (PAMORAs) in Oncologic Patients: from Scientific Evidence to Real Clinical Practice	4
Understanding the Clinical Implications of Low Penetrant Genes and Breast Cancer Risk	4
Chronic Lymphocytic Leukemia: Chemotherapy Free and Other Novel Therapies Including CAR T	4
Combinations of Chemotherapy and PD-1/PD-L1 Inhibitors in Sarcoma	4
COVID-19 and Gynecologic Oncology: What Have We Learned?	4
Novel Estrogen Receptor-Targeted Agents for Breast Cancer	4
Surgical Management of Metastatic Gastrointestinal Stromal Tumors	4
In Utero Development and Immunosurveillance of B Cell Acute Lymphoblastic Leukemia	4
Overview and Emerging Trends in the Treatment of Osteoradionecrosis	4
Is There Still a Role for Transplant for Patients with Mantle Cell Lymphoma (MCL) in the Era of CAR-T Cell Therapy?	4
Targeted Therapy in Early Stage Non-small Cell Lung Cancer	4
Central Nervous System Lymphoma: Novel Therapies	4