OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Immunology is 85. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Vaccine-induced memory	1045
Pathogenic T cells in post-viral lung disease in mice	866
The delivery device of SARS-CoV-2 mucosal vaccine matters	718
Orthogonal engineering of synthetic T cell states to enhance cancer immunotherapy	535
Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19	499
Charting granulopoietic disturbances in sepsis	468
Ironman training for NK cells	375
Author Correction: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection	371
Complement profile	333
Imprinting tissue immunity	329
3D imaging of the synovium defines an immune defense system at the blood–joint barrier	305
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1	264
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption	236
Keeping neonatal intestines happy	210
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self	195
Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice	183
A TNIP1-driven systemic autoimmune disorder with elevated IgG4	179
The complexity of immune evasion mechanisms throughout the metastatic cascade	174
Lactation-associated macrophages exist in murine mammary tissue and human milk	173
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function	173
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells	173
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer	171
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection	165
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes	162
Transposon-triggered innate immune response confers cancer resistance to the blind mole rat	160

Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity	153
CTLA-4 tail fusion enhances CAR-T antitumor immunity	152
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states	151
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease	151
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation	150
Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke	147
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity	146
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity	143
Defective fibrinolysis in periodontitis	141
Reversing T cell immunity reveals the basis for T cell lineage fate determination	138
KEAP1 maintains stemness	138
Nociceptors enhance humoral immunity	137
Restriction factor	136
A polarizing answer — microglia in Nasu-Hakola disease	135
Author Correction: Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	134
The road not taken en route to T cell exhaustion	134
A microbial iron fist to fight tumors	134
Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	133
Insights into autoimmunity and cancer	132
Enhancing T cell therapy	132
m1A tRNA modification facilitates rapid T cell proliferation	130
Aging lymph node responses	128
Learning from inborn errors	128
CAR macrophages on a fast track to solid tumor therapy	127
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting	125
G-CSF drives autoinflammation in APLAID	125
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens	125
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants	125
Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration	123
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity	123
JAK-STAT signaling maintains homeostasis in T cells and macrophages	122
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19	121
Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral Treg cell differentiation	119
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines	118
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis	117
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	117
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis	114
Aging disrupts circadian gene regulation and function in macrophages	110
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells	110
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis	108
Defining macrophages in the lactating murine mammary gland and human milk	108
Mucus needs GSDMD	107
Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells	105
Distinct developmental pathways generate functionally distinct populations of natural killer cells	105
Three cytokine pairs modulate sepsis effects at the organism level	104
What Jane Jacobs has taught me about neuroimmunology	104
Less BMI-1 is more for chronic infections	100
Role of the T cell vitamin D receptor in severe COVID-19	99
Reply to ‘Comment on: Repositioning TH cell polarization from single cytokines to complex help’	93
Transcriptional state and function of CD8+ memory T cells is linked to past proliferation	92

An IGHG1 variant exhibits polarized prevalence and confers enhanced IgG1 antibody responses against life-threatening organisms	92
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors	92
Prenatal and postnatal neuroimmune interactions in neurodevelopmental disorders	92
Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice	91
Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection	88
Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	88
Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation	85
Not-so-opposite ends of the spectrum: CD8+ T cell dysfunction across chronic infection, cancer and autoimmunity	85
Dynamic CD4+ T cell heterogeneity defines subset-specific suppression and PD-L1-blockade-driven functional restoration in chronic infection	85
Monocyte-derived IL-6 programs microglia to rebuild damaged brain vasculature	85