OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Immunology is 85. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-04-01 to 2026-04-01.)

Article	Citations
Vaccine-induced memory	718
Ironman training for NK cells	640
Keeping neonatal intestines happy	294
Imprinting tissue immunity	274
3D imaging of the synovium defines an immune defense system at the blood–joint barrier	274
Complement profile	273
Orthogonal engineering of synthetic T cell states to enhance cancer immunotherapy	271
Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19	258
TFH cell programs by pathogen and species	249
Pathogenic T cells in post-viral lung disease in mice	233
A little less reading, a little more type 9 action	233
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption	227
Neurons protect against fibrosis	227
Zika immune imprint risks dengue	223
CD8+ TRM cells and lung epithelial cells crosstalk	221
CTLA-4 tail fusion enhances CAR-T antitumor immunity	217
Charting granulopoietic disturbances in sepsis	213
The delivery device of SARS-CoV-2 mucosal vaccine matters	210
The complexity of immune evasion mechanisms throughout the metastatic cascade	201
Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke	197
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function	196
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states	196
Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice	195
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity	194
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1	187

Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes	183
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection	179
A TNIP1-driven systemic autoimmune disorder with elevated IgG4	177
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease	176
Secretogranin 2 binds LILRB4 resulting in immunosuppression	173
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer	173
Astrocyte TRAIL promotes GBM	173
Lactation-associated macrophages exist in murine mammary tissue and human milk	170
Author Correction: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection	169
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self	162
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells	153
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity	150
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation	147
Lymphocyte-derived cholinergic circuits modulate germinal center output and B cell activation	144
Nociceptors enhance humoral immunity	142
Restriction factor	140
m1A tRNA modification facilitates rapid T cell proliferation	138
Reversing T cell immunity reveals the basis for T cell lineage fate determination	138
Enhancing T cell therapy	131
Aging lymph node responses	129
Insights into autoimmunity and cancer	129
Six degrees of TGFβ	127
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity	126
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis	119
Microglia loss triggers glial stress and white matter damage in human leukodystrophy	118
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens	118
Learning from inborn errors	114
Carboxylation switch	114
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription	112
KEAP1 maintains stemness	109
A microbial iron fist to fight tumors	108
Author Correction: Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	108
Stemness for HIV control	108
Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	107
Beneficial role of GZMK+CD8+ T cells in neurodegeneration	105
The road not taken en route to T cell exhaustion	104
Active aldehydes drive metabolic exhaustion in CD8+ T cells	103
A polarizing answer — microglia in Nasu-Hakola disease	102
Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral Treg cell differentiation	101
CAR macrophages on a fast track to solid tumor therapy	100
Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity	100
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting	99
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19	96
Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt	95
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis	95
JAK-STAT signaling maintains homeostasis in T cells and macrophages	94
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity	94
G-CSF drives autoinflammation in APLAID	93
Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration	93
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	92

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants	92
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis	92
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis	91
2B or not 2B is the question in DC ontogeny	89
Defining macrophages in the lactating murine mammary gland and human milk	89
Three cytokine pairs modulate sepsis effects at the organism level	88
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors	87
What Jane Jacobs has taught me about neuroimmunology	87
Author Correction: A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity	86
Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells	85
Transcriptional state and function of CD8+ memory T cells is linked to past proliferation	85
Breastfeeding induces protective T cells	85