OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Immunology is 86. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Vaccine-induced memory	1077
The delivery device of SARS-CoV-2 mucosal vaccine matters	943
Orthogonal engineering of synthetic T cell states to enhance cancer immunotherapy	741
Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19	550
Charting granulopoietic disturbances in sepsis	544
Author Correction: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection	494
Complement profile	450
Imprinting tissue immunity	398
3D imaging of the synovium defines an immune defense system at the blood–joint barrier	353
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption	352
Keeping neonatal intestines happy	324
Astrocyte TRAIL promotes GBM	277
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity	227
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity	214
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1	201
CTLA-4 tail fusion enhances CAR-T antitumor immunity	193
A TNIP1-driven systemic autoimmune disorder with elevated IgG4	193
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states	189
Neurons protect against fibrosis	186
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes	177
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function	173
The complexity of immune evasion mechanisms throughout the metastatic cascade	171
Secretogranin 2 binds LILRB4 resulting in immunosuppression	169
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation	166
Transposon-triggered innate immune response confers cancer resistance to the blind mole rat	165

Pathogenic T cells in post-viral lung disease in mice	165
Lactation-associated macrophages exist in murine mammary tissue and human milk	158
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer	156
Ironman training for NK cells	156
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection	153
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self	151
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease	150
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells	150
Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke	147
Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice	145
Defective fibrinolysis in periodontitis	145
KEAP1 maintains stemness	144
Reversing T cell immunity reveals the basis for T cell lineage fate determination	143
A polarizing answer — microglia in Nasu-Hakola disease	141
Restriction factor	141
Nociceptors enhance humoral immunity	141
Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration	140
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity	140
Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity	138
Beneficial role of GZMK+CD8+ T cells in neurodegeneration	137
Microglia loss triggers glial stress and white matter damage in human leukodystrophy	137
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis	135
A microbial iron fist to fight tumors	135
The road not taken en route to T cell exhaustion	134
Author Correction: Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	133
Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	132
Enhancing T cell therapy	130
Insights into autoimmunity and cancer	129
m1A tRNA modification facilitates rapid T cell proliferation	128
Aging lymph node responses	125
Learning from inborn errors	125
G-CSF drives autoinflammation in APLAID	121
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	121
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells	118
Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral Treg cell differentiation	117
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity	117
Aging disrupts circadian gene regulation and function in macrophages	112
Carboxylation switch	111
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens	110
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis	108
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19	107
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis	107
JAK-STAT signaling maintains homeostasis in T cells and macrophages	103
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants	102
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis	101
Six degrees of TGFβ	101
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting	99
IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines	96
CAR macrophages on a fast track to solid tumor therapy	96
Defining macrophages in the lactating murine mammary gland and human milk	95

Mucus needs GSDMD	94
Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers	93
Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation	93
What Jane Jacobs has taught me about neuroimmunology	93
Distinct developmental pathways generate functionally distinct populations of natural killer cells	93
Three cytokine pairs modulate sepsis effects at the organism level	91
Less BMI-1 is more for chronic infections	90
Role of the T cell vitamin D receptor in severe COVID-19	89
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors	88
Reply to ‘Comment on: Repositioning TH cell polarization from single cytokines to complex help’	88
Transcriptional state and function of CD8+ memory T cells is linked to past proliferation	87
Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	86
Monocyte-derived IL-6 programs microglia to rebuild damaged brain vasculature	86