OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Immunology is 86. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Vaccine-induced memory	708
3D imaging of the synovium defines an immune defense system at the blood–joint barrier	335
Imprinting tissue immunity	331
Complement profile	325
Orthogonal engineering of synthetic T cell states to enhance cancer immunotherapy	312
Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19	271
Pathogenic T cells in post-viral lung disease in mice	269
Neurons protect against fibrosis	268
TFH cell programs by pathogen and species	267
Ironman training for NK cells	265
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption	252
CD8+ TRM cells and lung epithelial cells crosstalk	246
Zika immune imprint risks dengue	242
A little less reading, a little more type 9 action	233
The delivery device of SARS-CoV-2 mucosal vaccine matters	229
Charting granulopoietic disturbances in sepsis	214
Author Correction: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection	213
Inhibition of salt-inducible kinases reprograms T cells and antitumor immunity in ovarian cancer	213
A TNIP1-driven systemic autoimmune disorder with elevated IgG4	211
Keeping neonatal intestines happy	207
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes	204
Lymphocyte-derived cholinergic circuits modulate germinal center output and B cell activation	197
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells	194
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1	189
Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke	187

Secretogranin 2 binds LILRB4 resulting in immunosuppression	187
Astrocyte TRAIL promotes GBM	172
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self	171
The complexity of immune evasion mechanisms throughout the metastatic cascade	170
Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice	168
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity	168
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function	167
CTLA-4 tail fusion enhances CAR-T antitumor immunity	166
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation	163
Lactation-associated macrophages exist in murine mammary tissue and human milk	160
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease	153
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states	150
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer	147
Nociceptors enhance humoral immunity	144
Restriction factor	143
m1A tRNA modification facilitates rapid T cell proliferation	140
Enhancing T cell therapy	139
Insights into autoimmunity and cancer	134
The road not taken en route to T cell exhaustion	128
Microglia loss triggers glial stress and white matter damage in human leukodystrophy	127
Learning from inborn errors	125
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens	121
KEAP1 maintains stemness	119
Carboxylation switch	119
A polarizing answer — microglia in Nasu-Hakola disease	118
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription	117
A microbial iron fist to fight tumors	117
Active aldehydes drive metabolic exhaustion in CD8+ T cells	117
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	117
G-CSF drives autoinflammation in APLAID	116
Stemness for HIV control	116
Author Correction: Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	114
Beneficial role of GZMK+CD8+ T cells in neurodegeneration	112
Enzymatic cleavage weaponizes bacterial lipoproteins into immune tripwires	110
Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration	110
Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral Treg cell differentiation	109
Six degrees of TGFβ	108
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19	107
Costimulation drives CAR-T cell division fate	105
Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	103
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity	102
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity	100
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis	100
CAR macrophages on a fast track to solid tumor therapy	99
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis	98
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis	97
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting	97
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants	95
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis	95
JAK-STAT signaling maintains homeostasis in T cells and macrophages	95

Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity	95
Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt	94
Defining macrophages in the lactating murine mammary gland and human milk	93
Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation	92
Three cytokine pairs modulate sepsis effects at the organism level	91
What Jane Jacobs has taught me about neuroimmunology	90
Author Correction: A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity	88
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors	88
Breastfeeding induces protective T cells	88
LPS structure shapes Treg cells	87
Band-Aid for antibody production	87
An IGHG1 variant exhibits polarized prevalence and confers enhanced IgG1 antibody responses against life-threatening organisms	86
2B or not 2B is the question in DC ontogeny	86
Functional and dysfunctional T regulatory cell states in human tissues in RA and other autoimmune arthritic diseases	86
Distinct developmental pathways generate functionally distinct populations of natural killer cells	86