OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Immunology is 86. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Vaccine-induced memory	1088
The delivery device of SARS-CoV-2 mucosal vaccine matters	973
Orthogonal engineering of synthetic T cell states to enhance cancer immunotherapy	754
Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19	583
Author Correction: Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection	550
Complement profile	502
Imprinting tissue immunity	481
3D imaging of the synovium defines an immune defense system at the blood–joint barrier	413
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption	366
Keeping neonatal intestines happy	365
Astrocyte TRAIL promotes GBM	239
Neurons protect against fibrosis	221
The role of recruitment versus training in influenza-induced lasting changes to alveolar macrophage function	208
Pathogenic T cells in post-viral lung disease in mice	202
Vaccination reduces central nervous system IL-1β and memory deficits after COVID-19 in mice	198
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self	198
Ironman training for NK cells	194
Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity	183
Charting granulopoietic disturbances in sepsis	183
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection	179
Direct presentation of inflammation-associated self-antigens by thymic innate-like T cells induces elimination of autoreactive CD8+ thymocytes	179
CTLA-4 tail fusion enhances CAR-T antitumor immunity	178
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease	172
A TNIP1-driven systemic autoimmune disorder with elevated IgG4	167
The complexity of immune evasion mechanisms throughout the metastatic cascade	166

Lactation-associated macrophages exist in murine mammary tissue and human milk	163
Transposon-triggered innate immune response confers cancer resistance to the blind mole rat	159
Analysis of brain and blood single-cell transcriptomics in acute and subacute phases after experimental stroke	159
Memory B cell subsets have divergent developmental origins that are coupled to distinct imprinted epigenetic states	159
Secretogranin 2 binds LILRB4 resulting in immunosuppression	157
A little less reading, a little more type 9 action	155
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells	150
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity	149
Clonal succession after prolonged antiretroviral therapy rejuvenates CD8+ T cell responses against HIV-1	149
In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer	148
Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation	148
Defective fibrinolysis in periodontitis	147
Reversing T cell immunity reveals the basis for T cell lineage fate determination	146
Restriction factor	145
Nociceptors enhance humoral immunity	145
A polarizing answer — microglia in Nasu-Hakola disease	142
Beneficial role of GZMK+CD8+ T cells in neurodegeneration	142
Microglia loss triggers glial stress and white matter damage in human leukodystrophy	138
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis	138
Mutations in the human CSF1R gene impact microglia’s maintenance of brain white matter integrity	138
CAR macrophages on a fast track to solid tumor therapy	137
Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis	135
PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	135
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity	135
A microbial iron fist to fight tumors	134
The road not taken en route to T cell exhaustion	132
Author Correction: Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	127
Publisher Correction: PU.1 and BCL11B sequentially cooperate with RUNX1 to anchor mSWI/SNF to poise the T cell effector landscape	126
Insights into autoimmunity and cancer	125
Enhancing T cell therapy	125
m1A tRNA modification facilitates rapid T cell proliferation	122
Learning from inborn errors	117
G-CSF drives autoinflammation in APLAID	115
Aging lymph node responses	115
Carboxylation switch	114
Six degrees of TGFβ	113
Mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis	110
Cytokine polarized, alternatively activated bone marrow neutrophils drive axon regeneration	109
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19	107
Oleic acid availability impacts thymocyte preprogramming and subsequent peripheral Treg cell differentiation	106
Aging disrupts circadian gene regulation and function in macrophages	106
Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens	105
Type I interferon transcriptional network regulates expression of coinhibitory receptors in human T cells	105
KEAP1 maintains stemness	104
E3 ligase RAD18 targets phosphorylated IRF3 to terminate IFNB1 transcription	99
Circadian circuits control plasticity of group 3 innate lymphoid cells by sustaining epigenetic configuration of RORγt	98
JAK-STAT signaling maintains homeostasis in T cells and macrophages	98
GPR34 is a metabolic immune checkpoint for ILC1-mediated antitumor immunity	98
The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting	97
Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants	96

IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines	96
tRNA-m1A modification promotes T cell expansion via efficient MYC protein synthesis	96
Defining macrophages in the lactating murine mammary gland and human milk	95
Mucus needs GSDMD	93
What Jane Jacobs has taught me about neuroimmunology	92
Three cytokine pairs modulate sepsis effects at the organism level	90
Less BMI-1 is more for chronic infections	89
Role of the T cell vitamin D receptor in severe COVID-19	89
Reply to ‘Comment on: Repositioning TH cell polarization from single cytokines to complex help’	88
An IGHG1 variant exhibits polarized prevalence and confers enhanced IgG1 antibody responses against life-threatening organisms	87
Author Correction: Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors	87
Runx factors launch T cell and innate lymphoid programs via direct and gene network-based mechanisms	86