Cardiovascular Toxicology

Papers
(The TQCC of Cardiovascular Toxicology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling196
USP18 Curbs the Progression of Metabolic Hypertension by Suppressing JAK/STAT Pathway43
HIPK2 Confers Protection Against Septic Myocardial Injury by Regulating Ferroptosis41
Torsade de Pointes and QT Prolongation Among Antifungal Triazoles: A Real-World, Retrospective, Observational, Pharmacovigilance Analysis of the FDA Adverse Event Reporting System (FAERS) Database36
Cardioprotective Effects of ‘Vasant Kusumakar Rasa,’ a Herbo-metallic Formulation, in Type 2 Diabetic Cardiomyopathy in Rats32
Arterial Stiffness May Predict Subsequent Cancer Therapy-Related Cardiac Dysfunction in Breast Cancer Patients31
AT1 Receptors: Their Actions from Hypertension to Cognitive Impairment30
Ciprofloxacin Accelerates Angiotensin-II-Induced Vascular Smooth Muscle Cells Senescence Through Modulating AMPK/ROS pathway in Aortic Aneurysm and Dissection29
Novel Insights into Causal Effects of Serum Lipids and Apolipoproteins on Cardiovascular Morpho-Functional Phenotypes29
Zinc Overload Induces Damage to H9c2 Cardiomyocyte Through Mitochondrial Dysfunction and ROS-Mediated Mitophagy28
Association Between the Copper-to-Zinc Ratio and Cardiovascular Disease Among Chinese Adults: A China Multi-ethnic Cohort (CMEC) Study25
Biomarkers Related to Interferon-γ Pathway in Myocardial Ischemia–Reperfusion Injury and the Potential Molecular Mechanisms25
Interplay of Obesity, Ethanol, and Contaminant Mixture on Clinical Profiles of Cardiovascular and Metabolic Diseases: Evidence from an Animal Study24
Prevention of Mercury-Induced Cardiotoxicity After Short-Term Egg White Hydrolysate Supplementation in Rats23
Exosomes from Hypoxic Pretreatment ADSCs Ameliorate Cardiac Damage Post-MI via Activated circ-Stt3b/miR-15a-5p/GPX4 Signaling and Decreased Ferroptosis23
The Impact of Maternal/In Utero Exposure of Novel Tobacco Products on the Offspring Cardiovascular Health23
Determinants/Predictors of QT Abnormalities in Patients on Psychotropic Medications in a Nigerian Tertiary Hospital21
Genetically Predicted Apolipoprotein E Levels with the Risk of Panvascular Diseases: A Mendelian Randomization Study21
Association Between Heavy Metals Mixtures and Life’s Essential 8 Score in General US Adults20
Indoxyl Sulfate Activates NLRP3 Inflammasome to Induce Cardiac Contractile Dysfunction Accompanied by Myocardial Fibrosis and Hypertrophy19
Safety of Permissive Cardiotoxicity of Trastuzumab in Patients with Breast Cancer: A Systematic Review and Meta-Analysis19
Serum Proteomics Analysis of Patients with Ascending Aortic Dilation19
Blood Homocysteine Levels Mediate the Association Between Blood Lead Levels and Cardiovascular Mortality19
KLF9-Mediated Transcriptional Promotion of HMGB2 Accelerates Cardiomyocyte Apoptosis, Inflammation, and Ferroptosis in Myocardial Ischemia/Reperfusion Injury18
Cardioprotective Effects of the 4-Week Aerobic Running Exercises Before Treatment with Doxorubicin in Rats16
High Mobility Group Box 1 and Cardiovascular Diseases: Study of Act and Connect14
Vanillic Acid Mitigates Mitochondrial Dysfunction Induced by Lithium via Maintenance of Mitochondrial Function, Inhibition of Oxidative Stress, and Mitochondrial Swelling in Rat Heart-Isolated Mitocho14
Correction to: Predicting 30-Day Cardiotoxicity in Patients Receiving Immune Checkpoint Inhibitors: An Observational Study Utilizing XGBoost14
Chrysin Attenuates Myocardial Cell Apoptosis in Mice14
Cardiotoxicity of HER2-Targeted Drugs When Combined with Other Drugs: A Systematic and Meta-analysis of Randomized Controlled Trials14
On the Mechanisms of the Cardiotoxic Effect of Lead Oxide Nanoparticles14
Argatroban-Associated Adverse Events: An Analysis Based on FDA Adverse Event Reporting System (FAERS)14
Protective Effect of Sevoflurane Preconditioning on Cardiomyocytes Against Hypoxia/Reoxygenation Injury by Modulating Iron Homeostasis and Ferroptosis13
SIRT6 in Regulation of Mitochondrial Damage and Associated Cardiac Dysfunctions: A Possible Therapeutic Target for CVDs13
Association between Low Serum Testosterone Levels and All-cause Mortality in Patients With Cardiovascular Disease: A Study Based on the NHANES Database13
Prevalence, Outcomes, and Predictors of Prolonged Corrected QT Interval in Hydroxychloroquine-Naïve Hospitalized COVID-19 Patients12
Rhein Alleviates Doxorubicin-Induced Myocardial Injury by Inhibiting the p38 MAPK/HSP90/c-Jun/c-Fos Pathway-Mediated Apoptosis12
Association Between Serum Essential Metal Elements and Blood Pressure in Children: A Cohort Study11
Correlation Between Glycated Hemoglobin (HbA1c) and Post-Systolic Index Measured by Speckle-Tracking Echocardiography in Patients with Non-apparent Coronary Artery Disease11
TXB-001, A Newly-Developed Polymer-Conjugated Anthracycline, Alleviates Anthracycline-Induced Cardiotoxicity11
LncRNA HOTTIP Knockdown Attenuates Acute Myocardial Infarction via Regulating miR-92a-2/c-Met Axis11
The Role of Circular RNA in the Pathogenesis of Chemotherapy-Induced Cardiotoxicity in Cancer Patients: Focus on the Pathogenesis and Future Perspective11
Heavy Metal Scavenger Metallothionein Rescues Against Cold Stress-Evoked Myocardial Contractile Anomalies Through Regulation of Mitophagy10
The Long-Term Impact of Ionizing Radiation on DNA Damage in Patients Undergoing Multiple Cardiac Catheterizations10
The Worsening of Myocardial Ischemia–Reperfusion Injury in Uremic Cardiomyopathy is Further Aggravated by PM2.5 Exposure: Mitochondria Serve as the Central Focus of Pathology10
Potential Effects of Orally Ingesting Polyethylene Terephthalate Microplastics on the Mouse Heart10
Doxorubicin-Induced Cardiotoxicity: An Overview on Pre-clinical Therapeutic Approaches10
Anthracyclines-Induced Vascular Endothelial Dysfunction in Cancer Patients and Survivors Using Brachial Flow-Mediated Dilation (FMD) Tool: A Systematic Review and Meta-Analysis10
Salidroside Ameliorates Ischemia/Reperfusion-Induced Human Cardiomyocyte Injury by Inhibiting the Circ_0097682/miR-671-5p/USP46 Pathway9
The Preconditioning with Sevoflurane Alleviates Hypoxia-Reoxygenation-Induced Myocardial Cell Injury by Regulating the lncRNA LINC00265/miR-370-3p Axis9
Unraveling the Differentially Articulated Axes of the Century-Old Renin–Angiotensin–Aldosterone System: Potential Therapeutic Implications9
Exercise Training After Myocardial Infarction Enhances Endothelial Progenitor Cells Function via NRG-1 Signaling9
Cardiovascular Harmful Effects of Recommended Daily Doses (13 µg/kg/day), Tolerable Upper Intake Doses (0.14 mg/kg/day) and Twice the Tolerable Doses (0.28 mg/kg/day) of Copper9
The Protective Effect of Lasia spinosa (Linn.) Dissipates Chemical-Induced Cardiotoxicity in an Animal Model8
AhR Activation at the Air-Blood Barrier Alters Systemic microRNA Release After Inhalation of Particulate Matter Containing Environmentally Persistent Free Radicals8
Upregulation of Uric Acid Production and Caspase 3 Signalling Mediates Rohypnol-Induced Cardiorenal Damage8
The Acute Effect of Trimethylamine-N-Oxide on Vascular Function, Oxidative Stress, and Inflammation in Rat Aortic Rings8
Fermented Rooibos tea (Aspalathus linearis) Ameliorates Sodium Fluoride-Induced Cardiorenal Toxicity, Oxidative Stress, and Inflammation via Modulation of NF-κB/IκB/IκKB Signaling Pathway in Wistar Ra8
Overexpression of Programmed Cell Death 1 Prevents Doxorubicin-Induced Apoptosis Through Autophagy Induction in H9c2 Cardiomyocytes8
Hsa_circ_0032389 Enhances Proliferation and Migration in PDGF-BB-Induced Human Aortic Vascular Smooth Muscle Cells8
The Cardiovascular Burden of Gonadotropin-Releasing Hormone (GnRH) Therapy: Mechanisms, Risks, and Interventions8
TRIM21 Promotes Endothelial Cell Activation via Accelerating SOCS3 Ubiquitination Degradation in Atherosclerosis8
Taxifolin Protects Against 5-Fluorouracil-Induced Cardiotoxicity in Mice Through Mitigating Oxidative Stress, Inflammation, and Apoptosis: Possible Involvement of Sirt1/Nrf2/HO-1 Signaling8
Disruption of BACH1 Protects AC16 Cardiomyocytes Against Hypoxia/Reoxygenation-Evoked Injury by Diminishing CDKN3 Transcription8
Development and Validation of a Diagnostic Nomogram to Predict the Anthracycline-Induced Early Cardiotoxicity in Children with Hematological Tumors7
Evaluation of Environmental Contamination by Heavy Metals and Relationship with Cardiovascular Risk in a Population of Barcarena-PA7
Apatinib-Induced Hypertension Correlates with Improved Prognosis in Solid Tumor Patients7
Mercury-Mediated Cardiovascular Toxicity: Mechanisms and Remedies7
CELF1 Promotes Post-myocardial Infarction Cardiac Remodeling Via Suppression of FMO27
Alcohol Consumption: A New Risk Factor for Arterial Stiffness?7
Inhibition of CB1R in the Hypothalamic Paraventricular Nucleus Ameliorates Hypertension Through Wnt/β-Catenin/RAS Pathway7
Per- and Polyfluoroalkyl Substances (PFAS) Enhance Cholesterol Accumulation and Dysregulate Inflammatory Responses in Macrophages7
Targeting PPARs Signaling Pathways in Cardiotoxicity by Natural Compounds7
LncRNA AK020546 Alleviates Myocardial Ischemia–Reperfusion Injury via Suppressing METTL14/m6A/MST1 Axis-Mediated Ferroptosis7
Potential Role of Dipeptidyl Peptidase−4 in Regulating Mitochondria and Oxidative Stress in Cardiomyocytes7
Simvastatin Significantly Reduced Alcohol-Induced Cardiac Damage in Adolescent Mice7
Association Between the Uric Acid to High-Density Lipoprotein Cholesterol Ratio and Residual Risk for Coronary Artery Disease7
In Utero Nano-Titanium Dioxide Exposure Results in Sexually Dimorphic Weight Gain and Cardiovascular Function in Offspring7
Electrophysiological Profile of Different Antiviral Therapies in a Rabbit Whole-Heart Model7
miRNA-146a-5p Inhibits Hypoxia-Induced Myocardial Fibrosis Through EndMT6
MLN4924, A Neddylation Inhibitor, Improves the Vascular Reactivity but Causes Early Mortality in Polymicrobial Sepsis: Effect on Vascular RhoA/ROCK Signaling6
Arsenic-Induced Cardiovascular Diseases and their Correlation with Mitochondrial DNA Copy Number, Deletion, and Telomere Length in Bangladeshi Population6
The Protective Effects of Carvacrol Against Doxorubicin-Induced Cardiotoxicity In Vitro and In Vivo6
COMP Improves Ang-II-Induced Atrial Fibrillation via TGF-β Signaling Pathway6
SOX4 Promotes Ferroptosis to Aggravate Myocardial Ischemia/Reperfusion Injury Through Elevating DAPK1 Expression6
Nanomedicine-Based Strategies for Mitigating Chemo/Radiotherapy-Induced Cardiac Inflammation and Fibrosis6
CircRNA_102046 Affects the Occurrence and Development of Ischemic Stroke by Regulating the miR-493-5p/ROCK1 Signaling6
Association Between ABCG2 Polymorphism and Statin-Induced Adverse Events: A Meta-Analysis6
Yoda1/Piezo1 Alleviates Lipopolysaccharide-Induced Cardiac Injury via AMPK-Mediated Mitophagy6
Retraction Note: Dapagliflozin Guards Against Cadmium-Induced Cardiotoxicity via Modulation of IL6/STAT3 and TLR2/TNFα Signaling Pathways6
PM2.5 Exposure Lowers Mitochondrial Endurance During Cardiac Recovery in a Rat Model of Myocardial Infarction6
Advanced Cardiovascular Toxicity Screening: Integrating Human iPSC-Derived Cardiomyocytes with 2D In Silico Models6
Chronic Anatabine Administration Attenuates Cardiovascular Activity by Targeting NF-κB/NLRP3/Caspase-1-Dependent Pyroptosis and Oxidative Stress in Paraventricular Nucleus of Hypertensive Rat6
Associations Between Metal–Metal Interaction and the Risk of Hypertension: A Case–Control Study in Chinese Community-Dwelling Elderly6
Hormone Receptor Expression and QT interval at Baseline Correlate with Trastuzumab Associated Cardiotoxicity in HER2- Positive Breast Cancer Patients: A Prospective Study6
PD-1 Inhibitor-Induced Thyrotoxicosis Associated with Coronary Artery Spasm and Ventricular Tachycardia6
Association Between Mixed Exposure to Endocrine-Disrupting Chemicals and Cardiovascular Health: Results from the 2003–2016 NHANES6
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