Developmental Cell

Article	Citations
Disruption of H3K36 methylation provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis	384
Organoids from pluripotent stem cells and human tissues: When two cultures meet each other	266
Gut microbiota protect against colorectal tumorigenesis through lncRNA Snhg9	255
Spatiotemporal dynamics of the developing zebrafish enteric nervous system at the whole-organ level	219
Slow muscles guide fast myocyte fusion to ensure robust myotome formation despite the high spatiotemporal stochasticity of fusion events	212
Endothelial and Leptin Receptor+ cells promote the maintenance of stem cells and hematopoiesis in early postnatal murine bone marrow	209
Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR	192
Pancreatic alpha and beta cell fate choice is directed by apical-basal polarity dynamics	167
Microvilli control the morphogenesis of the tectorial membrane extracellular matrix	166
Negative elongation factor regulates muscle progenitor expansion for efficient myofiber repair and stem cell pool repopulation	156
An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions	155
YAP—deLIVERing the directions and the fuel	144
Cell geometry, signal dampening, and a bimodal transcriptional response underlie the spatial precision of an ERK-mediated embryonic induction	141
Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina	139
Autophagy-dependent changes in alternative splicing bias translation toward inflammation in senescent cells	117
The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells	117
A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain	111
Restoration of cone-circuit functionality in the regenerating adult zebrafish retina	107
Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception	106
Tracing embryonic hematopoiesis guides induction of pluripotent stem cells to hematopoietic progenitors	103
Epithelial cells adapt to curvature induction via transient active osmotic swelling	103
The elusive pulmonary neuroendocrine cell: How rare diseases may help solving common diseases	102
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential	100
Excess neuropeptides in lung signal through endothelial cells to impair gas exchange	99
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models	99

Transcription factor induction of vascular blood stem cell niches in vivo	99
Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state	95
CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones	93
Defining a TFAP2C-centered transcription factor network during murine peri-implantation	92
Characterization of the human fetal gonad and reproductive tract by single-cell transcriptomics	88
Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells	85
Tumor-induced disruption of the blood-brain barrier promotes host death	84
Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation	84
The developing murine kidney actively negotiates geometric packing conflicts to avoid defects	83
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks	83
Pyruvate modulation of redox potential controls mouse sperm motility	83
Two sides of the Dlk1-Dio3 story in imprinting	81
Paracellular transport: Opening the gates for growth	77
E3 ubiquitin ligase IPI1 controls rice immunity and flowering via both E3 ligase-dependent and -independent pathways	76
The evolutionarily conserved arginyltransferase 1 mediates a pVHL-independent oxygen-sensing pathway in mammalian cells	76
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes	75
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function	75
Changes in nuclear pore numbers control nuclear import and stress response of mouse hearts	74
An E-cadherin-actin clutch translates the mechanical force of cortical flow for cell-cell contact to inhibit epithelial cell locomotion	73
Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila	73
May the force be with you: Mechanosensitivity shapes dendrite development	72
Lysosomes to the rescue: Anterograde axonal lysosome transport and neuronal proteostasis	69
Shedding light on stem cells: Optogenetics uncover the role of ERK dynamics in pluripotency	68
The membrane surface as a platform that organizes cellular and biochemical processes	67
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome	66
Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination	66
Response to Matters Arising: Intercellular genetic tracing of cardiac endothelium in the developing heart	65
Rejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling	63
Peripheral but critical: Translation of germ granule mRNAs in zebrafish	63
From nuclear to extracellular PTEN: Multiple roles in tumor suppression and immune modulation	63
Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon	62
Single-cell omics identifies inflammatory signaling as a trans-differentiation trigger in mouse embryos	61
A mechanism to PLAse the eye	61
cAMP controls a trafficking mechanism that maintains the neuron specificity and subcellular placement of electrical synapses	60
Giving translation a hand	60
Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration	60
Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos	59
A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland	59
Variability of cross-tissue X-chromosome inactivation characterizes timing of human embryonic lineage specification events	58
Clone competition as a mechanism to reduce tumor formation	58
VAB-8 stops dynein in its tracks to regulate synaptic delivery	57
Soaping up transcriptional condensates	56
Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins	55
Acute brain vascular regeneration occurs via lymphatic transdifferentiation	54
Laying out the mammalian body plan to a T	54
Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration	53
Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo	53
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility	53
Spatial patterning controls neuron numbers in the Drosophila visual system	52
Tao and Rap2l ensure proper Misshapen activation and levels during Drosophila border cell migration	51

Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding	51
Is developmental synchrony enabled by CTCF residence time?	50
scRNA-seq data from the larval Drosophila ventral cord provides a resource for studying motor systems function and development	50
A leucine-derived fatty acid unlocks the mTOR to development	50
A temporal allocation of amino acid resources ensures fitness and body allometry in Drosophila	50
AGO1 controls protein folding in mouse embryonic stem cell fate decisions	50
Improving stem cell-derived pancreatic islets using single-cell multi-inferred regulomes	50
A limb bud morphogen bites the dust	49
ER-phagy responses in yeast, plants, and mammalian cells and their crosstalk with UPR and ERAD	48
Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation	48
PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay	47
Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye	47
SRSF1 governs progenitor-specific alternative splicing to maintain adult epithelial tissue homeostasis and renewal	47
Actuation of single downstream nodes in growth factor network steers immune cell migration	46
T cell cytoskeletal forces shape synapse topography for targeted lysis via membrane curvature bias of perforin	46
Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2	46
Mechanics of spindle orientation in human mitotic cells is determined by pulling forces on astral microtubules and clustering of cortical dynein	45
A transcriptional and regulatory map of mouse somite maturation	45
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage	45
A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration	45
Breaking new ground: Decoding the root’s molecular circuits to penetrate compacted soil	45
Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase	45
Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling	45
Myosin waves and a mechanical asymmetry guide the oscillatory migration of Drosophila cardiac progenitors	45
Heart regeneration: 20 years of progress and renewed optimism	45
A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression	44
Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells	44
Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleation	43
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity	43
Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos	43
Soybean symbiotic-nodule zonation and cell differentiation are defined by NIN2 signaling and GH3-dependent auxin homeostasis	43
Optimizing rice grain size by attenuating phosphorylation-triggered functional impairment of a chromatin modifier ternary complex	43
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N-methyladenosine	42
The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis	42
The p-rpS6-zone delineates wounding responses and the healing process	42
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients	42
An SLC12A9-dependent ion transport mechanism maintains lysosomal osmolarity	42
An amino acid-resolution interactome for motile cilia identifies the structure and function of ciliopathy protein complexes	41
Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo	41
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells	40
Evolving insights into pancreatic tumor initiation and progression through DCLK1-expressing tuft cells	40
Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling	40
Mast cells proliferate in the peri-hippocampal space during early development and modulate local and peripheral immune cells	40
Rapid and robust optogenetic control of gene expression in Drosophila	39
Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development	39
Single-cell analysis of human testis aging and correlation with elevated body mass index	39
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress	38
SALSA, a genetically encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo	38
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation	37
Plasticity in airway smooth muscle differentiation during mouse lung development	37
PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport	37
TREX1-dependent DNA damage links nuclear rupture to tumor cell invasion	37
Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard	37
Age-associated interplay between zinc deficiency and Golgi stress hinders microtubule-dependent cellular signaling and epigenetic control	37
Itaconate uptake via SLC13A3 improves hepatic antibacterial innate immunity	35
Epigenetic reprogramming enables NF1A/B oncogenic role in SHH medulloblastoma	35
LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force	35
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages	35
Proteolysis-free amoeboid migration of melanoma cells through crowded environments via bleb-driven worrying	35
Apical polarity and actomyosin dynamics control Kibra subcellular localization and function in Drosophila Hippo signaling	34
A single-cell transcriptomic census of mammalian olfactory epithelium aging	34
A Ca2+-sensor switch for tolerance to elevated salt stress in Arabidopsis	34
Endoplasmic reticulum exit sites are segregated for secretion based on cargo size	34
Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis	33
A tubule-sheet continuum model for the mechanism of nuclear envelope assembly	33
ER nests are specialized ER subdomains in Arabidopsis where peroxisomes and lipid droplets form	33
Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture in C. elegans	33
Maternal and embryonic signals cause functional differentiation of luminal epithelial cells and receptivity establishment	33
Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells	32
RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development	32
Single-nucleus sequencing deciphers developmental trajectories in rice pistils	32
α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics	32
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies	32
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness	32
Human embryonic and fetal biobanking: Establishing the Dutch Fetal Biobank and a framework for standardization	32
Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos	32
Mammalian autophagosomes form from finger-like phagophores	32
Temporal regulation of vegetative phase change in plants	31
Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions	31
A human breast atlas integrating single-cell proteomics and transcriptomics	31

Consumption of a polarized membrane reservoir drives asymmetric membrane expansion during the unequal divisions of neural stem cells	31
Surviving and thriving: How plants perceive and respond to temperature stress	31
The central moTOR of metabolism	31
SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis	31
Apoptotic extracellular vesicle formation via local phosphatidylserine exposure drives efficient cell extrusion	31
A single-cell Arabidopsis root atlas reveals developmental trajectories in wild-type and cell identity mutants	31
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy	31
VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites	31
Gibberellin and cytokinin signaling antagonistically control female-germline cell specification in Arabidopsis	30
Vimentin intermediate filaments coordinate actin stress fibers and podosomes to determine the extracellular matrix degradation by macrophages	30
A Drosophila holidic diet optimized for growth and development	30
Synthetic Notch receptors and their applications to study cell-cell contacts in vivo	30
SUMO style defense: How post-translational modification via SUMO conjugation promotes plant defense	30
STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma	30
Seamless knockins in Drosophila via CRISPR-triggered single-strand annealing	30
Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions	29
NanoDam identifies Homeobrain (ARX) and Scarecrow (NKX2.1) as conserved temporal factors in the Drosophila central brain and visual system	29
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis	29
Girl power: NORTIA polarization seals pollen tube fate	29
Biased cell adhesion organizes the Drosophila visual motion integration circuit	29
Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue	29
Shaping the heart with mechanosensitive shrinking cells	29
Lewis Wolpert (1929–2021)	28
“Fateful” encounter: Lineage tracing meets phylogeny to unravel mysteries of cancer progression	28
A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies	28
Pollen-stigma incompatibility within and between species: Tread lightly, sedate the dogs, and don’t wake the guards!	28
A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange	28
Can’t smell the virus: SARS-CoV-2, chromatin organization, and anosmia	28
Lysosomal catabolic activity promotes the exit of murine totipotent 2-cell state by silencing early-embryonic retrotransposons	27
DYRK1A-TGF-β signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma	27
Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development	27
Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis	27
BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development	27
The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms	27
A twist in Pitx2 regulation of gut looping	27
The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells	27
KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling	27
Calcium-dependent protein kinases CPK3/4/6/11 and 27 respond to osmotic stress and activate SnRK2s in Arabidopsis	27
Stepping on the molecular brake: Slowing down proliferation to allow differentiation	27
HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis	27
Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila	27
Znhit1 controls meiotic initiation in male germ cells by coordinating with Stra8 to activate meiotic gene expression	26
Hox gene activity directs physical forces to differentially shape chick small and large intestinal epithelia	26
Oct4 controls basement membrane development during human embryogenesis	26
Ehf controls mammary alveolar lineage differentiation and is a putative suppressor of breast tumorigenesis	26
Root twisting drives halotropism via stress-induced microtubule reorientation	26
Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling	25
The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms	25
Gliotransmission and adenosine signaling promote axon regeneration	25
Philip N. Benfey (1953–2023)	25
Mouse placenta fetal macrophages arise from endothelial cells outside the placenta	25
Construction of single-cell cross-species chromatin accessibility landscapes with combinatorial-hybridization-based ATAC-seq	24
Mechano-electrical transduction components TMC1-CIB2 undergo a Ca2+-induced conformational change linked to hearing loss	24
Modeling myelin: A toolkit for exploring myelin’s mysteries in vitro	24
BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration	24
Control of murine brown adipocyte development by GATA6	24
Restoration of CPEB4 prevents muscle stem cell senescence during aging	24
Understanding totipotency: A role for alternative splicing	24
Generation and application of endogenously floxed alleles for cell-specific knockout in zebrafish	24
Breaking down barriers: Tumors make a leaky brain	24
Losing the license to regenerate hair cells	23
MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement	23
Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling	23
Stir it up: The role of actin in mitochondrial mixing during mitosis	23
Feeling the pressure: A mechanical tale of the pollen tube journey through the pistil	23
A junction-dependent mechanism drives murine mammary cell intercalation for ductal elongation	23
Bacterial developmental checkpoint that directly monitors cell surface morphogenesis	23
How structural interactions and receptor phosphorylation shape strigolactone signaling in rice	23
Initiation and maintenance of the pluripotent epiblast in pre-implantation human development is independent of NODAL signaling	23
Decoding anterior-posterior axis emergence among mouse, monkey, and human embryos	23
Neuroblastoma differentiation in vivo excludes cranial tumors	23
Traveling to the left: A story of PKD1L1-containing vesicles	22
Nuclear receptor Nr5a2 promotes diverse connective tissue fates in the jaw	22
Eomes restricts Brachyury functions at the onset of mouse gastrulation	22
Maintaining the structural and functional homeostasis of the plant endoplasmic reticulum	22
YAP1 and PRDM14 converge to promote cell survival and tumorigenesis	22
New adventures in spatial transcriptomics	22
Adhesion-based capture stabilizes nascent microvilli at epithelial cell junctions	22
Axonal endoplasmic reticulum tubules control local translation via P180/RRBP1-mediated ribosome interactions	22
Multimodal mass spectrometry imaging identifies cell-type-specific metabolic and lipidomic variation in the mammalian liver	22
A mechanical wave travels along a genetic guide to drive the formation of an epithelial furrow during Drosophila gastrulation	22
Shifts in keratin isoform expression activate motility signals during wound healing	22
Coordination between endoderm progression and mouse gastruloid elongation controls endodermal morphotype choice	22
Global mapping of glycosylation pathways in human-derived cells	22
In vitro generation of mouse morula-like cells	22
Xist Repeats B and C, but not Repeat A, mediate de novo recruitment of the Polycomb system in X chromosome inactivation	21
Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex	21
Tumor-derived MMPs regulate cachexia in a Drosophila cancer model	21
Dynamic death decisions: How mitochondrial dynamics shape cellular commitment to apoptosis and ferroptosis	21
Understanding the microenvironment and how this controls cell fate	21
UV-induced reduction in Polycomb repression promotes epidermal pigmentation	21
Global versus local matrix remodeling drives rotational versus invasive collective migration of epithelial cells	21
Visceral mesoderm signaling regulates assembly position and function of the Drosophila testis niche	20
Differential growth is an emergent property of mechanochemical feedback mechanisms in curved plant organs	20
The microtubular preprophase band recruits Myosin XI to the cortical division site to guide phragmoplast expansion during plant cytokinesis	20