Developmental Cell

Article	Citations
Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding	263
cAMP controls a trafficking mechanism that maintains the neuron specificity and subcellular placement of electrical synapses	244
TREX1-dependent DNA damage links nuclear rupture to tumor cell invasion	229
Epithelial cells adapt to curvature induction via transient active osmotic swelling	204
Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation	166
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients	164
HOPX-associated molecular programs control cardiomyocyte cell states underpinning cardiac structure and function	152
Mechanisms of ferroptosis sensitization and resistance	144
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models	129
Spatial patterning controls neuron numbers in the Drosophila visual system	124
A transcriptional and regulatory map of mouse somite maturation	122
CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones	121
Diet suppresses glioblastoma initiation in mice by maintaining quiescence of mutation-bearing neural stem cells	113
Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR	112
Control of poly(A)-tail length and translation in vertebrate oocytes and early embryos	110
Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions	107
ORF3a of SARS-CoV-2 promotes lysosomal exocytosis-mediated viral egress	107
Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfβ-Id2 axis, for tissue regeneration	106
Rapid and robust optogenetic control of gene expression in Drosophila	103
SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis	101
A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration	100
A human breast atlas integrating single-cell proteomics and transcriptomics	93
Restoration of cone-circuit functionality in the regenerating adult zebrafish retina	93
Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard	92
Mechanics of spindle orientation in human mitotic cells is determined by pulling forces on astral microtubules and clustering of cortical dynein	90

Partial closure of the γ-tubulin ring complex by CDK5RAP2 activates microtubule nucleation	90
E3 ubiquitin ligase IPI1 controls rice immunity and flowering via both E3 ligase-dependent and -independent pathways	90
Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila	83
Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo	81
Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy	80
Bifunctional transcription factor GhMYB4 orchestrates transition from elongation to secondary cell wall synthesis trade-off in cotton fiber	79
Maternal and embryonic signals cause functional differentiation of luminal epithelial cells and receptivity establishment	78
Organoids from pluripotent stem cells and human tissues: When two cultures meet each other	75
BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration	74
Distinct classes of lagging chromosome underpin age-related oocyte aneuploidy in mouse	73
How structural interactions and receptor phosphorylation shape strigolactone signaling in rice	72
YAP1 and PRDM14 converge to promote cell survival and tumorigenesis	69
The miR-430 locus with extreme promoter density forms a transcription body during the minor wave of zygotic genome activation	67
Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling	67
A condensates-to-VPS41-associated phagic vacuoles conversion pathway controls autophagy degradation in plants	66
Can’t smell the virus: SARS-CoV-2, chromatin organization, and anosmia	65
Pollen-stigma incompatibility within and between species: Tread lightly, sedate the dogs, and don’t wake the guards!	65
Bidirectional activation of stem-like programs between metastatic cancer and alveolar type 2 cells within the niche	64
Lysosomal catabolic activity promotes the exit of murine totipotent 2-cell state by silencing early-embryonic retrotransposons	64
MAP9/MAPH-9 supports axonemal microtubule doublets and modulates motor movement	62
SUMO style defense: How post-translational modification via SUMO conjugation promotes plant defense	61
Vimentin intermediate filaments coordinate actin stress fibers and podosomes to determine the extracellular matrix degradation by macrophages	61
Traveling to the left: A story of PKD1L1-containing vesicles	59
Axon guidance in central nervous system regeneration	58
Dynamic control of H2A.Zub and H3K27me3 by ambient temperature during cell fate determination in Arabidopsis	58
Nucleolar protein PEXF controls ribosomal RNA synthesis and pluripotency exit	58
The microtubular preprophase band recruits Myosin XI to the cortical division site to guide phragmoplast expansion during plant cytokinesis	57
Seamless knockins in Drosophila via CRISPR-triggered single-strand annealing	57
Don’t fear the reaper: The role of regulated cell death in tumorigenesis and BH3-mimetics for cancer therapy	57
SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway	56
Stepping on the molecular brake: Slowing down proliferation to allow differentiation	55
Setting up cAMP in plants	54
Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids	53
Tumor-derived MMPs regulate cachexia in a Drosophila cancer model	53
Genetic variation associated with condensate dysregulation in disease	53
An Oatp transporter-mediated steroid sink promotes tumor-induced cachexia in Drosophila	53
Xyloglucan side chains enable polysaccharide secretion to the plant cell wall	53
The endophilin curvature-sensitive motif requires electrostatic guidance to recycle synaptic vesicles in vivo	53
Human yolk sac-derived innate lymphoid-biased multipotent progenitors emerge prior to hematopoietic stem cell formation	53
Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport	51
KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling	51
Nitric oxide controls stomatal development and stress responses by inhibiting MPK6 phosphorylation via S-nitrosylation in Arabidopsis	50
Fibrous periosteum repairs bone fracture and maintains the healed bone throughout mouse adulthood	50
Nuclear receptor Nr5a2 promotes diverse connective tissue fates in the jaw	50
Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis	50
20 years of Developmental Cell: Looking forward	50
Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila	50
Adaptive mechanoproperties mediated by the formin FMN1 characterize glioblastoma fitness for invasion	50
Immune mechanisms shape the clonal landscape during early progression of prostate cancer	49
CLMP is a tumor suppressor that determines all-trans retinoic acid response in colorectal cancer	49

Pten, PI3K, and PtdIns(3,4,5)P3 dynamics control pulsatile actin branching in Drosophila retina morphogenesis	48
Vasculature is getting Hip(po): Hippo signaling in vascular development and disease	48
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis	48
A single-cell census of mouse limb development identifies complex spatiotemporal dynamics of skeleton formation	48
Mesodermal fibronectin controls cell shape, polarity, and mechanotransduction in the second heart field during cardiac outflow tract development	48
ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells	48
Understanding the cell fate and behavior of progenitors at the origin of the mouse cardiac mitral valve	47
Separase cleaves the kinetochore protein Meikin at the meiosis I/II transition	47
VAMP2 controls murine epidermal differentiation and carcinogenesis by regulation of nucleophagy	47
Allelic transcriptomic profiling identifies the role of PRD-like homeobox genes in human embryonic-cleavage-stage arrest	47
Smooth muscle contributes to the development and function of a layered intestinal stem cell niche	47
Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC1	46
Extracellular matrix assembly stress initiates Drosophila central nervous system morphogenesis	45
Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells	45
Adhesion tunes speed and persistence by coordinating protrusions and extracellular matrix remodeling	45
Bending toward differentiation	44
Assembly of tight junction belts by ZO1 surface condensation and local actin polymerization	44
Optogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotency	44
Septins regulate border cell surface geometry, shape, and motility downstream of Rho in Drosophila	44
Mechanical regulation of substrate adhesion and de-adhesion drives a cell-contractile wave during Drosophila tissue morphogenesis	44
Seriously cilia: A tiny organelle illuminates evolution, disease, and intercellular communication	43
Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method	43
TDRD1 phase separation drives intermitochondrial cement assembly to promote piRNA biogenesis and fertility	42
Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging	42
Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract	42
Transgenesis in the acoel worm Hofstenia miamia	42
Localized glucose import, glycolytic processing, and mitochondria generate a focused ATP burst to power basement-membrane invasion	41
Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis	40
Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis	40
Plant glutamate receptors mediate a bet-hedging strategy between regeneration and defense	40
The BAS chromatin remodeler determines brassinosteroid-induced transcriptional activation and plant growth in Arabidopsis	40
RNA N6-methyladenosine modification promotes auxin biosynthesis required for male meiosis in rice	39
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity	39
Spatially resolved proteomics of the Arabidopsis stomatal lineage identifies polarity complexes for cell divisions and stomatal pores	39
Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation	39
An antisense RNA forms R-loop to facilitate the transcription of CBF genes and plant cold acclimation	39
Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens	38
Distinct p53 isoforms code for opposing transcriptional outcomes	38
Decoding the organization, dynamics, and function of the 4D genome	38
GLRs: Mediating a defense-regeneration tradeoff in plants	38
20 years of Developmental Cell: Looking back	38
ZINC FINGER PROTEIN2 suppresses funiculus lignification to ensure seed loading efficiency in Arabidopsis	37
Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells	37
Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model	36
Developmental angiocrine diversification of endothelial cells for organotypic regeneration	36
Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells	36
A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase	36
Mitochondrial GTP metabolism controls reproductive aging in C. elegans	36
Sweat gland development requires an eccrine dermal niche and couples two epidermal programs	36
Actomyosin contractility in olfactory placode neurons opens the skin epithelium to form the zebrafish nostril	36
Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells	36
Integration of vascular progenitors into functional blood vessels represents a distinct mechanism of vascular growth	35
A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis	35
Microenvironmental innate immune signaling and cell mechanical responses promote tumor growth	35
Deceleration of the cell cycle underpins a switch from proliferative to terminal divisions in plant stomatal lineage	35
Metabolic plasticity drives development during mammalian embryogenesis	35
A Scribble/Cdep/Rac pathway controls follower-cell crawling and cluster cohesion during collective border-cell migration	34
Formation of polarized contractile interfaces by self-organized Toll-8/Cirl GPCR asymmetry	34
Wnt signaling couples G2 phase control with differentiation during hematopoiesis in Drosophila	34
Collective oscillatory signaling in Dictyostelium discoideum acts as a developmental timer initiated by weak coupling of a noisy pulsatile signal	34
ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer	34
Spatial transcriptional mapping of the human nephrogenic program	34
Persistent cell contacts enable E-cadherin/HMR-1- and PAR-3-based symmetry breaking within a developing C. elegans epithelium	33
Gene module reconstruction identifies cellular differentiation processes and the regulatory logic of specialized secretion in zebrafish	33
Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development	33
Antagonistic systemin receptors integrate the activation and attenuation of systemic wound signaling in tomato	33
Asymmetric partitioning of persistent paternal mitochondria during cell divisions safeguards embryo development and mitochondrial inheritance	33
Building a kidney tree: Functional collecting duct from human pluripotent stem cells	33
A subset of neutrophils activates anti-tumor immunity and inhibits non-small-cell lung cancer progression	33
In the mouse cortex, oligodendrocytes regain a plastic capacity, transforming into astrocytes after acute injury	32
4D reconstruction of murine developmental trajectories using spherical harmonics	32
Notochord segmentation in zebrafish controlled by iterative mechanical signaling	32
Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and promotes stress fiber repair	31
Long noncoding RNA ARTA controls ABA response through MYB7 nuclear trafficking in Arabidopsis	31
Cell death: Revisiting the roads to ruin	31
An exception to the rule? Regeneration of the injured spinal cord in the spiny mouse	31
Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice	31
Fate mapping in mouse demonstrates early secretory differentiation directly from Lgr5+ intestinal stem cells	31
Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate	31
Oncogene-regulated release of extracellular vesicles	30

Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster	30
The Hitchhiker’s Guide across a Waddington’s landscape of melanoma	30
Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival	30
A chromatin code for limb segment identity in axolotl limb regeneration	30
ZNFX-1 keeps RNAi in the loop	30
Dual states of murine Bmi1-expressing intestinal stem cells drive epithelial development utilizing non-canonical Wnt signaling	30
PITTching in for lysosome repair	30
Hepatocytic lipocalin-2 controls HDL metabolism and atherosclerosis via Nedd4-1-SR-BI axis in mice	29
Toll receptors remodel epithelia by directing planar-polarized Src and PI3K activity	29
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation	29
Activity-dependent local protection and lateral inhibition control synaptic competition in developing mitral cells in mice	29
Evolutionarily conserved midbody remodeling precedes ring canal formation during gametogenesis	29
Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation	29
YAP regulates an SGK1/mTORC1/SREBP-dependent lipogenic program to support proliferation and tissue growth	29
Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration	28
Controlling pyroptosis through post-translational modifications of gasdermin D	28
An unexpected puzzle piece links polarity and chromosome segregation	28
TaANK-TPR1 enhances wheat resistance against stripe rust via controlling gene expression and protein activity of NLR protein TaRPP13L1	28
How meningeal macrophages control medulloblastoma induction	28
Mending microtubules enhances cell polarity	28
Inherited nuclear pore substructures template post-mitotic pore assembly	28
The mechanical state of pre-tumoral epithelia controls subsequent Drosophila tumor aggressiveness	28
Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast	28
SigmaR1 shapes rough endoplasmic reticulum membrane sheets	27
DDX20 is required for cell-cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice	27
Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse	27
An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration	27
EYA protein complex is required for Wntless retrograde trafficking from endosomes to Golgi	27
Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells	27
Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation	27
A postsynaptic GPR158-PLCXD2 complex controls spine apparatus abundance and dendritic spine maturation	27
Human yolk sac-derived innate lymphoid-biased multipotent progenitors emerge prior to hematopoietic stem cell formation	27
Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover	27
Molecular and spatial landmarks of early mouse skin development	26
Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD	26
Reshaping of the tumor microenvironment by cellular senescence: An opportunity for senotherapies	26
Meningeal macrophages inhibit chemokine signaling in pre-tumor cells to suppress mouse medulloblastoma initiation	26
Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming	26
Glutamine-dependent signaling controls pluripotent stem cell fate	26
ATG5 provides host protection acting as a switch in the atg8ylation cascade between autophagy and secretion	26
Giving translation a hand	26
From nuclear to extracellular PTEN: Multiple roles in tumor suppression and immune modulation	25
Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina	25
Differential condensation of sister chromatids acts with Cdc6 to ensure asynchronous S-phase entry in Drosophila male germline stem cell lineage	25
Caveolae sense oxidative stress through membrane lipid peroxidation and cytosolic release of CAVIN1 to regulate NRF2	25
Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos	25
The elusive pulmonary neuroendocrine cell: How rare diseases may help solving common diseases	25
Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase	25
The Drosophila adult midgut progenitor cells arise from asymmetric divisions of neuroblast-like cells	25
A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression	25
A limb bud morphogen bites the dust	25
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks	25
An SLC12A9-dependent ion transport mechanism maintains lysosomal osmolarity	25
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential	25
Endoplasmic reticulum exit sites are segregated for secretion based on cargo size	24
Heart regeneration: 20 years of progress and renewed optimism	24
A single-cell transcriptomic census of mammalian olfactory epithelium aging	24
Mast cells proliferate in the peri-hippocampal space during early development and modulate local and peripheral immune cells	24
Cell cycle regulation of ER membrane biogenesis protects against chromosome missegregation	24
Acute brain vascular regeneration occurs via lymphatic transdifferentiation	24
Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye	24
Ubiquitin ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes	24
RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness	24
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility	24
Mammalian autophagosomes form from finger-like phagophores	23
Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies	23
“Fateful” encounter: Lineage tracing meets phylogeny to unravel mysteries of cancer progression	23
Identifying cross-lineage dependencies of cell-type-specific regulators in mouse gastruloids	23
Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter	23
Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon	23
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity	23
Transport properties of canonical PIN-FORMED proteins from Arabidopsis and the role of the loop domain in auxin transport	23
Control of murine brown adipocyte development by GATA6	23
Outer mitochondrial membrane E3 Ub ligase MARCH5 controls de novo peroxisome biogenesis	23
Plasticity in airway smooth muscle differentiation during mouse lung development	23
Regulation of reverse electron transfer at mitochondrial complex I by unconventional Notch action in cancer stem cells	23
Philip N. Benfey (1953–2023)	23
Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization	23
Restoration of CPEB4 prevents muscle stem cell senescence during aging	22
Differential growth is an emergent property of mechanochemical feedback mechanisms in curved plant organs	22
Directed cell invasion and asymmetric adhesion drive tissue elongation and turning in C. elegans gonad morphogenesis	22
Tissue-resident macrophages specifically express Lactotransferrin and Vegfc during ear pinna regeneration in spiny mice	22
Comparative single-cell multiome identifies evolutionary changes in neural progenitor cells during primate brain development	22
New adventures in spatial transcriptomics	22
Waves of regulated protein expression and phosphorylation rewire the proteome to drive gametogenesis in budding yeast	22
Gliotransmission and adenosine signaling promote axon regeneration	22
Functional heterogeneity of Wnt-responsive and Hedgehog-responsive neural stem cells in the murine adult hippocampus	22
Synthetic Notch receptors and their applications to study cell-cell contacts in vivo	21
The default and directed pathways of hepatoblast differentiation involve distinct epigenomic mechanisms	21
Extracellular mechanical forces drive endocardial cell volume decrease during zebrafish cardiac valve morphogenesis	21
Unlocking trophectoderm mysteries: In vivo and in vitro perspectives on human and mouse trophoblast fate induction	21
The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms	21
Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling	21
Blood and bones: Mechanical cues and Hippo signaling drive vascular invasion during limb formation	20
An essential signaling cascade for avian auditory hair cell regeneration	20