Experimental Biology and Medicine

Article	Citations
Paraoxonase 1 rs662 polymorphism, its related variables, and COVID-19 intensity: Considering gender and post-COVID complications	87
Dual detection of COVID-19 antigens and antibodies using nanoscale fluorescent plasmonic substrates	61
Circulating exosomal microRNA-4497 as a potential biomarker for metastasis and prognosis in non-small-cell lung cancer	41
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	37
Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats	35
Roles of IL-33 in the Pathogenesis of Cardiac Disorders	35
Bioinformatics analysis of the genes associated with co-occurrence of heart failure and lung cancer	33
Participation of ASK-1 in the cardiomyocyte-protective role of mechanical ventilation in a rat model of myocardial infarction	30
A primordial target: Mitochondria mediate both primary and collateral anesthetic effects of volatile anesthetics	29
Gentiopicroside alleviates acute myocardial infarction injury in rats by disrupting Nrf2/NLRP3 signaling	29
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	28
Mild hypobaric hypoxia influences splenic proliferation during the later phase of stress erythropoiesis	26
The influence of multidisciplinary team clinic on the prognosis of patients with chronic kidney disease	26
Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling	25
Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments	25
The continuing evolution of barcode applications: Functional toxicology to cell lineage	25
Serum homocysteine is a valuable marker for predicting aggravation of infection in intestinal obstruction patients	24
Classifying and evaluating fetuses with multicystic dysplastic kidney in etiologic studies	24
Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence	24
Data science in drug discovery safety: Challenges and opportunities	24
S-allylmercapto-N-acetylcysteine protects bone cells from oxidation and improves femur microarchitecture in healthy and diabetic mice	24
Retraction Notice	23
Inferences of carboplatin response-related signature by integrating multiomics data in ovarian serous cystadenocarcinoma	23
Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis	23
Phenotyping in clinical text with unsupervised numerical reasoning for patient stratification	23

Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy	23
Thermo- and pH-sensitive nanoparticles of poly (N-isopropylacrylamide-decenoic acid-1-vinylimidazole) for ultrasound switchable fluorescence imaging	22
Interleukin-10 regulates starvation-induced autophagy through the STAT3-mTOR-p70s6k axis in hepatic stellate cells	22
Exogenous surfactant reduces inflammation and redox imbalance in rats under prone or supine mechanical ventilation	22
Gene expression profile suggests different mechanisms underlying sporadic and familial mesial temporal lobe epilepsy	22
In-ovo imaging using ostrich eggs: Biomagnetism for detection of cardiac signals and embryonal motion	21
The role of IL-33/ST2 signaling in the tumor microenvironment and Treg immunotherapy	21
TBX1 regulates myogenic differentiation by activating the TGFβ-Smad2/3 pathway in myoblasts	20
Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis	19
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	19
Fluoride induces osteoblast autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway in vivo and in vitro	19
Arbovirus surveillance in mosquitoes: Historical methods, emerging technologies, and challenges ahead	18
Explainable hierarchical clustering for patient subtyping and risk prediction	18
The contribution of the immune system to genitourinary fibrosis	18
Ubiquinol-cytochrome c reductase core protein 1 contributes to cardiac tolerance to acute exhaustive exercise	18
Structural and molecular biology of Sabiá virus	18
Artificial neural network–based diagnostic models for lung cancer combining conventional indicators with tumor markers	18
Evaluation of the mechanisms of heme-induced tissue factor activation: Contribution of innate immune pathways	18
CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats	18
Maternal serum-derived exosomal lactoferrin as a marker in detecting and predicting ventricular septal defect in fetuses	18
Statistical considerations for outcomes in clinical research: A review of common data types and methodology	18
Manipulation of unfolded protein response by zoonotic vaccinia virus strains Guarani P1 and Passatempo	17
Corrigendum	17
Effect of smoking on the redox status of knee osteoarthritis: A preliminary study	16
Rhubarb extract rebuilding the mucus homeostasis and regulating mucin-associated flora to relieve constipation	16
Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs	16
Dapagliflozin-entresto protected kidney from renal hypertension via downregulating cell-stress signaling and upregulating SIRT1/PGC-1α/Mfn2-medicated mitochondrial homeostasis	16
Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma	16
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer	16
Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways	16
JAK inhibitors for the treatment of VEXAS syndrome	15
Mechanisms of disease-associated SINE-VNTR-Alus	15
A novel fluorescent traceable carbon quantum dots with selective antibacterial activity against Porphyromonas gingivalis	15
GDF15plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets	15
Review on ultrasound-guided photoacoustic imaging for complementary analyses of biological systems in vivo	15
Visceral fat sympathectomy ameliorates systemic and local stress response related to chronic sleep restriction	14
The dengue virus 4 component of NIAID’s tetravalent TV003 vaccine drives its innate immune signature	14
Aedes-borne orthoflavivirus infections in neotropical primates – Ecology, susceptibility, and pathogenesis	14
Hydroxytyrosol produced by engineered Escherichia coli strains activates Nrf2/HO-1 pathway: An in vitro and in vivo study	14
Alpha-linolenic acid enhances the facilitation of GABAergic neurotransmission in the BLA and CA1	14
Plasma Galectin-3 and H-FABP correlate with poor physical performance in patients with congestive heart failure	14
Metformin inhibits mitochondrial dysfunction and apoptosis in cardiomyocytes induced by high glucose via upregulating AMPK activity	14
The inducible prostaglandin E synthase (mPGES-1) in neuroinflammatory disorders	14
Repurposing medications for treatment of age-related macular degeneration: Insights from novel approaches to data mining	14
Allele-specific silencing by RNAi of R92Q and R173W mutations in cardiac troponin T	14
Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators	13
Therapeutic effects of kartogenin on temporomandibular joint injury by activating the TGF-β/SMAD pathway in rats	13
Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models	13
Comparative transcriptome analysis of endothelial progenitor cells of HbSS patients with and without proliferative retinopathy	13
Clinicopathological significance and underlying molecular mechanism of downregulation of basonuclin 1 expression in ovarian carcinoma	13

How S100B crosses brain barriers and why it is considered a peripheral marker of brain injury	12
Seasonal variation and disease distribution of cytophagocytic mononuclear cells in synovial fluid: A medical record study	12
Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes	12
Proteomics analysis of carotid body tumor revealed potential mechanisms and molecular differences among Shamblin classifications	12
Revolutionized virome research using systems microbiology approaches	12
Deep learning diagnostic performance and visual insights in differentiating benign and malignant thyroid nodules on ultrasound images	12
Changes in gene expression and neuroinflammation in the hippocampus of rats with poststroke cognitive impairment	12
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19	12
Osteopontin as a biomarker for COVID-19 severity and multisystem inflammatory syndrome in children: A pilot study	12
Epstein-Barr virus genotype-1 and Mediterranean + strain in gastric cancer biopsies of Ghanaian patients	12
Applied artificial intelligence in healthcare: Listening to the winds of change in a post-COVID-19 world	12
RxBERT: Enhancing drug labeling text mining and analysis with AI language modeling	12
Elevated SARS-CoV-2 in peripheral blood and increased COVID-19 severity in American Indians/Alaska Natives	12
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3′-UTR in de-differentiated and undifferentiated hepatocyte	12
COVID-19 active case findings based on self-collected saliva samples with CRISPR-Cas12a detection	12
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	11
Apelin-13 prevents the effects of oxygen–glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT–mTOR signaling	11
Identifying a cervical cancer survival signature based on mRNA expression and genome-wide copy number variations	11
A quantum-based oversampling method for classification of highly imbalanced and overlapped data	11
Diagnostic and prognostic nomograms for newly diagnosed intrahepatic cholangiocarcinoma with brain metastasis: A population-based analysis	11
The β-catenin/CBP signaling axis participates in sepsis-induced inflammatory lung injury	11
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography	10
MicroRNA 205-5p and COVID-19 adverse outcomes: Potential molecular biomarker and regulator of the immune response	10
CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model	10
Recombinant antigen delivery to dendritic cells as a way to improve vaccine design	10
Association between serum placental growth factor and vascular endothelial function in hyprtensive disorders complicating pregnancy	10
Molecular and environmental contributors to neurological complications in sickle cell disease	10
Penicillin-binding protein (PBP) inhibitor development: A 10-year chemical perspective	10
TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways	10
Vagal milieu or electrophysiologic substrate? The link between atrial fibrillation and obstructive sleep apnea	10
New and effective method to develop primary hepatocytes from liver cancer patients	10
Eugenol alleviates neuronal damage via inhibiting inflammatory process against pilocarpine-induced status epilepticus	10
Improved protocol for Bst polymerase and reverse transcriptase production and application to a point-of-care diagnostics system	10
Antibiotic impregnation and nanocoating of external ventricular drainage catheters for antibacterial applications: Evaluation of in vitro studies and molecular docking	10
Data-driven approach to quantify trust in medical devices using Bayesian networks	10
Focused ultrasound stimulation on meibomian glands for the treatment of evaporative dry eye	10
Whole-genome sequencing as a first-tier diagnostic framework for rare genetic diseases	9
A comprehensive overview of PPM1A: From structure to disease	9
Isotyping and quantitation of the humoral immune response to SARS-CoV-2	9
Leonurine pretreatment protects the heart from myocardial ischemia-reperfusion injury	9
2-Bromopalmitate inhibits malignant behaviors of HPSCC cells by hindering the membrane location of Ras protein	9
GP5 regulates epithelial–mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway	9
The role of ketamine in major depressive disorders: Effects on parvalbumin-positive interneurons in hippocampus	9
Progress in the contrary effects of glucagon-like peptide-1 and chemerin on obesity development	9
Comparison of circulating bacterial profiles between mild and severe COVID-19 patients	9
Surface fibrils on the particles of nucleocytoviruses: A review	9
Ultrasonographic assessment of skeletal muscles after experimentally induced neurogenic inflammation (facet injury) in rats	9
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure	9
Intermittent hypoxia promotes the recovery of motor function in rats with cerebral ischemia by regulating mitochondrial function	9
Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model	9
Na+/K+-ATPase DR region antibody ameliorated cardiac hypertrophy and fibrosis in rats with 5/6 nephrectomy	9
Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment	9
Role of follistatin-like protein 1 in liver diseases	9
Transcellular routes of blood–brain barrier disruption	8
Testing lncRNAs signature as clinical stage–related prognostic markers in gastric cancer progression using TCGA database	8
Monitoring and modulation of the tumor microenvironment for enhanced cancer modeling	8
Bio-hybrid electronic and photonic devices	8
Comorbidities involving parasitic diseases: A look at the benefits and complications	8
Absence of antibody responses to SARS-CoV-2 N protein in COVID-19 vaccine breakthrough cases	8
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions	8
Human stem cell–derived neurons and neural circuitry therapeutics: Next frontier in spinal cord injury repair	8
Febuxostat ameliorates APAP-induced acute liver injury by activating Keap1/Nrf2 and inhibiting TLR4/NF-κB p65 pathways	8
Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic	8
Delivery of microRNA-21-sponge and pre-microRNA-122 by MS2 virus-like particles to therapeutically target hepatocellular carcinoma cells	8
TRIM29 promotes the progression of colorectal cancer by suppressing EZH2 degradation	8
TXNIP activates NLRP3/IL-1β and participate in inflammatory response and oxidative stress to promote deep venous thrombosis	8
Protective effect of dexmedetomidine on intestinal mucosal barrier function in rats after cardiopulmonary bypass	8
Link between m6A modification and infiltration characterization of tumor microenvironment in lung adenocarcinoma	8
Nanocarrier-mediated curcumin delivery: An adjuvant strategy for CNS disease treatment	8
Perinatal methadone exposure attenuates myelination and induces oligodendrocyte apoptosis in neonatal rat brain	8
Circulating lncRNAs NONHSAT054669.2 and ENST00000525337 can be used as early biomarkers of gestational diabetes mellitus	8
Construction and predictive value of risk models of maternal serum alpha-fetoprotein variants and fetal open neural tube defects	8
Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson’s disease	8
Plasmodium vivax transcriptomics: What is new?	8
X-linked hypophosphatemia, fibroblast growth factor 23 signaling, and craniosynostosis	8
Imbalance of follicular regulatory T (Tfr) cells/follicular helper T (Tfh) cells in adult patients with primary immune thrombocytopenia	8
Ceramides and other sphingolipids as predictors of incident dysglycemia (CASPID): Design, methods, and baseline characteristics	8
Analysis of dengue fever disease in West Africa	8
Wnt signaling in biliary development, proliferation, and fibrosis	8
Synergetic enrichment of aggrecan in nucleus pulposus cells by scAAV6-shRNA-mediated knockdown of aggrecanase-1 and aggrecanase-2	8

Bioactive, full-length parathyroid hormone delivered using an adeno-associated viral vector	7
Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease	7
Triterpenoid CDDO-EA inhibits lipopolysaccharide-induced inflammatory responses in skeletal muscle cells through suppression of NF-κB	7
Whole-genome analysis and evolutionary characterization of cervical and oral human papillomavirus 16	7
Inflammation and mitochondria in the pathogenesis of chronic Chagas disease cardiomyopathy	7
Intranasal administration of mitochondria improves spatial memory in olfactory bulbectomized mice	7
The skeleton in a physical world	7
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis	7
Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia	7
Role of autophagy and its regulation by noncoding RNAs in ovarian cancer	7
Preface: 2022 International Conference on Neuroprotective Agents	7
Lipocalin-2, S100A8/A9, and cystatin C: Potential predictive biomarkers of cardiovascular complications in COVID-19	7
A metabolism-relevant signature as a predictor for prognosis and therapeutic response in pancreatic cancer	7
Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPRmt	7
Corrigendum to “CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats”	7
Deletion of ghrelin alters tryptophan metabolism and exacerbates experimental ulcerative colitis in aged mice	7
Decreased PPP1R3G in pre-eclampsia impairs human trophoblast invasion and migration via Akt/MMP-9 signaling pathway	7
Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods	7
Topology and redescriptions detect multiple alternative biological pathways from clinical phenotypes	7
Antiviral activity of medicinal plant-derived products against SARS-CoV-2	6
Implications of fibrotic extracellular matrix in diabetic retinopathy	6
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy	6
What does desmin do: A bibliometric assessment of the functions of the muscle intermediate filament	6
Heterogeneity of humoral response patterns in mildly symptomatic, non-hospitalized COVID-19 patients: A one-year longitudinal study	6
Decision rules for personalized statin treatment prescriptions over multi-objectives	6
A review on photo-mediated ultrasound therapy	6
TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19	6
Contusion concomitant with ischemia injury aggravates skeletal muscle necrosis and hinders muscle functional recovery	6
Therapeutically leveraging GABAA receptors in cancer	6
Neutrophil extracellular traps contributing to atherosclerosis: From pathophysiology to clinical implications	6
Sex differences in muscle SIRT1 and SIRT3 and exercise + weight loss effects on muscle sirtuins	6
Mesenchymal stem cells with p38 mitogen-activated protein kinase interference ameliorate mouse ischemic stroke	6
Transcriptomic profiling of cerebrospinal fluid identifies ALS pathway enrichment and RNA biomarkers in MND individuals	6
Effects of moderate-continuous and high-intensity interval aerobic training on cardiac function of spontaneously hypertensive rats	6
Mouse embryonic stem cells require multiple amino acids	6
Identifying immune subtypes of uterine corpus endometrial carcinoma and a four-paired-lncRNA signature with immune-related lncRNAs	6
Single-nucleotide polymorphisms of TLR4 and GAS7 linked to primary open-angle glaucoma among patients of Shenyang, China	6
Evolving techniques for reducing phantom limb pain	6
Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis	6
Dietary supplementation with L-leucine reduces nitric oxide synthesis by endothelial cells of rats	6
N-acetylcysteine improves autism-like behavior by recovering autophagic deficiency and decreasing Notch-1/Hes-1 pathway activity	6
EXPRESSION OF CONCERN: Chondroitin-4-Sulphate Reduced Oxidative Injury in Caerulein-Induced Pancreatitis in Mice: The Involvement of NF-κB Translocation and Apoptosis Activation	6
Enriched environment as a nonpharmacological neuroprotective strategy	6
Effects of autoimmune abnormalities on skeletal muscle regeneration after needle puncture in mice	6
Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat	6
Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats	6
Retraction Notice	5
Quercetin suppresses ovariectomy-induced osteoporosis in rat mandibles by regulating autophagy and the NLRP3 pathway	5
An overview of viral chitinases: General properties and biotechnological potential	5
Photoacoustic imaging systems based on clinical ultrasound platform	5
Ultrasound in ocular oncology: Technical advances, clinical applications, and limitations	5
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle	5
Overall and cancer-specific survival in patients with breast Paget disease: A population-based study	5
Neonatal sevoflurane exposure induces long-term changes in dendritic morphology in juvenile rats and mice	5
Islet cell encapsulation – Application in diabetes treatment	5
Weighted gene co-expression network analysis reveals the hub genes associated with pulmonary hypertension	5
Decellularization of the human urethra for tissue engineering applications	5
Is graphene the rock upon which new era continuous glucose monitors could be built?	5
Everolimus-induced hyperpermeability of endothelial cells causes lung injury	5
Mechanisms maintaining cerebral perfusion during systemic hypotension are impaired in elderly adults	5
Gene expression patterns and related pathways in the hearts of rhesus monkeys subjected to prolonged myocardial ischemia	5
Cyclin D1b induces changes in the macrophage phenotype resulting in promotion of tumor metastasis	5
Alteration of endothelial permeability ensures cardiomyocyte survival from ischemic insult in the subendocardium of the heart	5
Dietary supplementation with L-citrulline improves placental angiogenesis and embryonic survival in gilts	5
Is type 2 diabetes mellitus another intercellular junction-related disorder?	5
Renal cystic disease in tuberous sclerosis complex	5
Reduced expression of transmembrane protein 43 during cardiac hypertrophy leads to worsening heart failure in mice	5
Identification and validation of hub genes in CD5-positive diffuse large B-cell lymphoma	5
4-Octyl itaconate alleviates renal ischemia reperfusion injury by ameliorating endoplasmic reticulum stress via Nrf2 pathway	5
MicroRNA regulation of BAG3	5
Evaluation methodology for deep learning imputation models	5
Unraveling the physiologic paradoxes that underlie exercise prescription for stress fracture prevention	5
Pink1 promotes cell proliferation and affects glycolysis in breast cancer	5
Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery	5
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients	5
The U.S. Food and Drug Administration, the mechanism of action, and other considerations for cell-based therapy candidates	5
CX3CR1 deficiency exacerbates immune-mediated hepatitis by increasing NF-κB-mediated cytokine production in macrophage and T cell	5
Corrigendum	5
Protective effect of astaxanthin on tuberculosis-associated inflammatory lung injury	5