Experimental Biology and Medicine

Article	Citations
Circulating exosomal microRNA-4497 as a potential biomarker for metastasis and prognosis in non-small-cell lung cancer	77
Dual detection of COVID-19 antigens and antibodies using nanoscale fluorescent plasmonic substrates	59
Paraoxonase 1 rs662 polymorphism, its related variables, and COVID-19 intensity: Considering gender and post-COVID complications	44
Participation of ASK-1 in the cardiomyocyte-protective role of mechanical ventilation in a rat model of myocardial infarction	37
Bioinformatics analysis of the genes associated with co-occurrence of heart failure and lung cancer	35
Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats	34
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	33
A primordial target: Mitochondria mediate both primary and collateral anesthetic effects of volatile anesthetics	33
Roles of IL-33 in the Pathogenesis of Cardiac Disorders	33
Mild hypobaric hypoxia influences splenic proliferation during the later phase of stress erythropoiesis	30
The influence of multidisciplinary team clinic on the prognosis of patients with chronic kidney disease	29
The continuing evolution of barcode applications: Functional toxicology to cell lineage	28
Combining tissue clearing and Fluoro-Jade C labeling for neurotoxicity assessments	27
S-allylmercapto-N-acetylcysteine protects bone cells from oxidation and improves femur microarchitecture in healthy and diabetic mice	25
Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling	25
Gentiopicroside alleviates acute myocardial infarction injury in rats by disrupting Nrf2/NLRP3 signaling	24
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	24
Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence	24
Arbovirus surveillance in mosquitoes: Historical methods, emerging technologies, and challenges ahead	23
Classifying and evaluating fetuses with multicystic dysplastic kidney in etiologic studies	23
Retraction Notice	23
Data science in drug discovery safety: Challenges and opportunities	23
Phenotyping in clinical text with unsupervised numerical reasoning for patient stratification	23
Serum homocysteine is a valuable marker for predicting aggravation of infection in intestinal obstruction patients	23
CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats	22

Inferences of carboplatin response-related signature by integrating multiomics data in ovarian serous cystadenocarcinoma	22
Statistical considerations for outcomes in clinical research: A review of common data types and methodology	22
Dysregulation of multiple signaling pathways: A possible cause of cerebral palsy	22
Interleukin-10 regulates starvation-induced autophagy through the STAT3-mTOR-p70s6k axis in hepatic stellate cells	22
Gene expression profile suggests different mechanisms underlying sporadic and familial mesial temporal lobe epilepsy	21
Thermo- and pH-sensitive nanoparticles of poly (N-isopropylacrylamide-decenoic acid-1-vinylimidazole) for ultrasound switchable fluorescence imaging	21
Exogenous surfactant reduces inflammation and redox imbalance in rats under prone or supine mechanical ventilation	21
Evaluation of the mechanisms of heme-induced tissue factor activation: Contribution of innate immune pathways	20
Ubiquinol-cytochrome c reductase core protein 1 contributes to cardiac tolerance to acute exhaustive exercise	20
The role of IL-33/ST2 signaling in the tumor microenvironment and Treg immunotherapy	20
In-ovo imaging using ostrich eggs: Biomagnetism for detection of cardiac signals and embryonal motion	20
Fluoride induces osteoblast autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway in vivo and in vitro	19
TBX1 regulates myogenic differentiation by activating the TGFβ-Smad2/3 pathway in myoblasts	19
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	19
Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis	18
Corrigendum	18
Beclin1- and Atg13-dependent autophagy activation and morroniside have synergistic effect on osteoblastogenesis	18
Structural and molecular biology of Sabiá virus	18
Explainable hierarchical clustering for patient subtyping and risk prediction	18
Review on ultrasound-guided photoacoustic imaging for complementary analyses of biological systems in vivo	18
Expression of cytoskeleton-associated protein 4 is associated with poor prognosis and metastasis in nasopharyngeal carcinoma	17
Effect of smoking on the redox status of knee osteoarthritis: A preliminary study	17
Manipulation of unfolded protein response by zoonotic vaccinia virus strains Guarani P1 and Passatempo	17
GDF15plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets	17
Hydroxytyrosol produced by engineered Escherichia coli strains activates Nrf2/HO-1 pathway: An in vitro and in vivo study	16
The contribution of the immune system to genitourinary fibrosis	16
Tastin promotes non-small-cell lung cancer progression through the ErbB4, PI3K/AKT, and ERK1/2 pathways	16
Artificial neural network–based diagnostic models for lung cancer combining conventional indicators with tumor markers	16
The inducible prostaglandin E synthase (mPGES-1) in neuroinflammatory disorders	16
Maternal serum-derived exosomal lactoferrin as a marker in detecting and predicting ventricular septal defect in fetuses	16
JAK inhibitors for the treatment of VEXAS syndrome	16
Mechanisms of disease-associated SINE-VNTR-Alus	16
Rhubarb extract rebuilding the mucus homeostasis and regulating mucin-associated flora to relieve constipation	15
A novel fluorescent traceable carbon quantum dots with selective antibacterial activity against Porphyromonas gingivalis	15
Synthesis of glycine from 4-hydroxyproline in tissues of neonatal pigs	15
Dapagliflozin-entresto protected kidney from renal hypertension via downregulating cell-stress signaling and upregulating SIRT1/PGC-1α/Mfn2-medicated mitochondrial homeostasis	15
Repurposing medications for treatment of age-related macular degeneration: Insights from novel approaches to data mining	14
Plasma Galectin-3 and H-FABP correlate with poor physical performance in patients with congestive heart failure	14
Seasonal variation and disease distribution of cytophagocytic mononuclear cells in synovial fluid: A medical record study	14
Comparative transcriptome analysis of endothelial progenitor cells of HbSS patients with and without proliferative retinopathy	14
The dengue virus 4 component of NIAID’s tetravalent TV003 vaccine drives its innate immune signature	14
LOXL2 reduces 5-FU sensitivity through the Hedgehog/BCL2 signaling pathway in colorectal cancer	14
Alpha-linolenic acid enhances the facilitation of GABAergic neurotransmission in the BLA and CA1	14
Epstein-Barr virus genotype-1 and Mediterranean + strain in gastric cancer biopsies of Ghanaian patients	14
Metformin inhibits mitochondrial dysfunction and apoptosis in cardiomyocytes induced by high glucose via upregulating AMPK activity	14
Visceral fat sympathectomy ameliorates systemic and local stress response related to chronic sleep restriction	14
Allele-specific silencing by RNAi of R92Q and R173W mutations in cardiac troponin T	14
An increase in polyadenylation of histone isoforms, Hist1h2ah and Hist2h3c2, is governed by 3′-UTR in de-differentiated and undifferentiated hepatocyte	14
Elevated SARS-CoV-2 in peripheral blood and increased COVID-19 severity in American Indians/Alaska Natives	13
Revolutionized virome research using systems microbiology approaches	13

Therapeutic effects of kartogenin on temporomandibular joint injury by activating the TGF-β/SMAD pathway in rats	13
COVID-19 active case findings based on self-collected saliva samples with CRISPR-Cas12a detection	13
Respiratory viral infection and resolution of inflammation: Roles for specialized pro-resolving mediators	12
Clinicopathological significance and underlying molecular mechanism of downregulation of basonuclin 1 expression in ovarian carcinoma	12
How S100B crosses brain barriers and why it is considered a peripheral marker of brain injury	12
Changes in gene expression and neuroinflammation in the hippocampus of rats with poststroke cognitive impairment	12
Eugenol alleviates neuronal damage via inhibiting inflammatory process against pilocarpine-induced status epilepticus	12
RxBERT: Enhancing drug labeling text mining and analysis with AI language modeling	12
Analyses of lung cancer-derived volatiles in exhaled breath and in vitro models	12
Applied artificial intelligence in healthcare: Listening to the winds of change in a post-COVID-19 world	12
Osteopontin as a biomarker for COVID-19 severity and multisystem inflammatory syndrome in children: A pilot study	12
Deep learning diagnostic performance and visual insights in differentiating benign and malignant thyroid nodules on ultrasound images	12
Aedes-borne orthoflavivirus infections in neotropical primates – Ecology, susceptibility, and pathogenesis	12
Telmisartan ameliorates cardiac fibrosis and diastolic function in cardiorenal heart failure with preserved ejection fraction	12
Proteomics analysis of carotid body tumor revealed potential mechanisms and molecular differences among Shamblin classifications	12
Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes	11
Identifying a cervical cancer survival signature based on mRNA expression and genome-wide copy number variations	11
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	11
Apelin-13 prevents the effects of oxygen–glucose deprivation/reperfusion on bEnd.3 cells by inhibiting AKT–mTOR signaling	11
The β-catenin/CBP signaling axis participates in sepsis-induced inflammatory lung injury	11
Influence of polymorphic variations of IFNL, HLA, and IL-6 genes in severe cases of COVID-19	11
Diagnostic and prognostic nomograms for newly diagnosed intrahepatic cholangiocarcinoma with brain metastasis: A population-based analysis	11
A quantum-based oversampling method for classification of highly imbalanced and overlapped data	11
CRISPR/SaCas9-based gene editing rescues photoreceptor degeneration throughout a rhodopsin-associated autosomal dominant retinitis pigmentosa mouse model	10
Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model	10
Focused ultrasound stimulation on meibomian glands for the treatment of evaporative dry eye	10
Antibiotic impregnation and nanocoating of external ventricular drainage catheters for antibacterial applications: Evaluation of in vitro studies and molecular docking	10
ONECUT2 which is targeted by hsa-miR-15a-5p enhances stemness maintenance of gastric cancer stem cells	10
Penicillin-binding protein (PBP) inhibitor development: A 10-year chemical perspective	10
TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways	10
Recombinant antigen delivery to dendritic cells as a way to improve vaccine design	10
A comprehensive overview of PPM1A: From structure to disease	10
Molecular and environmental contributors to neurological complications in sickle cell disease	10
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography	10
Improved protocol for Bst polymerase and reverse transcriptase production and application to a point-of-care diagnostics system	10
Delayed tezampanel and caramiphen treatment but not midazolam protects against long-term neuropathology after soman exposure	10
Data-driven approach to quantify trust in medical devices using Bayesian networks	10
Role of follistatin-like protein 1 in liver diseases	10
New and effective method to develop primary hepatocytes from liver cancer patients	10
MicroRNA 205-5p and COVID-19 adverse outcomes: Potential molecular biomarker and regulator of the immune response	10
Association between serum placental growth factor and vascular endothelial function in hyprtensive disorders complicating pregnancy	10
Vagal milieu or electrophysiologic substrate? The link between atrial fibrillation and obstructive sleep apnea	10
Na+/K+-ATPase DR region antibody ameliorated cardiac hypertrophy and fibrosis in rats with 5/6 nephrectomy	9
GP5 regulates epithelial–mesenchymal transition in breast cancer via the PI3K/AKT signaling pathway	9
Perinatal methadone exposure attenuates myelination and induces oligodendrocyte apoptosis in neonatal rat brain	9
Whole-genome sequencing as a first-tier diagnostic framework for rare genetic diseases	9
Intermittent hypoxia promotes the recovery of motor function in rats with cerebral ischemia by regulating mitochondrial function	9
Leonurine pretreatment protects the heart from myocardial ischemia-reperfusion injury	9
Surface fibrils on the particles of nucleocytoviruses: A review	9
Comparison of circulating bacterial profiles between mild and severe COVID-19 patients	9
2-Bromopalmitate inhibits malignant behaviors of HPSCC cells by hindering the membrane location of Ras protein	9
Human stem cell–derived neurons and neural circuitry therapeutics: Next frontier in spinal cord injury repair	9
Progress in the contrary effects of glucagon-like peptide-1 and chemerin on obesity development	9
Ultrasonographic assessment of skeletal muscles after experimentally induced neurogenic inflammation (facet injury) in rats	9
Isotyping and quantitation of the humoral immune response to SARS-CoV-2	9
Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment	9
Analysis of dengue fever disease in West Africa	9
The role of ketamine in major depressive disorders: Effects on parvalbumin-positive interneurons in hippocampus	9
Protective effect of dexmedetomidine on intestinal mucosal barrier function in rats after cardiopulmonary bypass	8
TXNIP activates NLRP3/IL-1β and participate in inflammatory response and oxidative stress to promote deep venous thrombosis	8
Plasmodium vivax transcriptomics: What is new?	8
Non-reference genome transposable elements (TEs) have a significant impact on the progression of the Parkinson’s disease	8
Transcellular routes of blood–brain barrier disruption	8
Wnt signaling in biliary development, proliferation, and fibrosis	8
Absence of antibody responses to SARS-CoV-2 N protein in COVID-19 vaccine breakthrough cases	8
Comorbidities involving parasitic diseases: A look at the benefits and complications	8
Bio-hybrid electronic and photonic devices	8
Circulating lncRNAs NONHSAT054669.2 and ENST00000525337 can be used as early biomarkers of gestational diabetes mellitus	8
Testing lncRNAs signature as clinical stage–related prognostic markers in gastric cancer progression using TCGA database	8
Delivery of microRNA-21-sponge and pre-microRNA-122 by MS2 virus-like particles to therapeutically target hepatocellular carcinoma cells	8
TRIM29 promotes the progression of colorectal cancer by suppressing EZH2 degradation	8
The multifunctionality of expression systems in Bacillus subtilis: Emerging devices for the production of recombinant proteins	8
Ceramides and other sphingolipids as predictors of incident dysglycemia (CASPID): Design, methods, and baseline characteristics	8
Imbalance of follicular regulatory T (Tfr) cells/follicular helper T (Tfh) cells in adult patients with primary immune thrombocytopenia	8
Link between m6A modification and infiltration characterization of tumor microenvironment in lung adenocarcinoma	8
Synergetic enrichment of aggrecan in nucleus pulposus cells by scAAV6-shRNA-mediated knockdown of aggrecanase-1 and aggrecanase-2	8
Construction and predictive value of risk models of maternal serum alpha-fetoprotein variants and fetal open neural tube defects	8
Monitoring and modulation of the tumor microenvironment for enhanced cancer modeling	8
Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic	8
Febuxostat ameliorates APAP-induced acute liver injury by activating Keap1/Nrf2 and inhibiting TLR4/NF-κB p65 pathways	8

Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions	8
Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPRmt	7
Role of autophagy and its regulation by noncoding RNAs in ovarian cancer	7
Inflammation and mitochondria in the pathogenesis of chronic Chagas disease cardiomyopathy	7
Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods	7
Whole-genome analysis and evolutionary characterization of cervical and oral human papillomavirus 16	7
Deletion of ghrelin alters tryptophan metabolism and exacerbates experimental ulcerative colitis in aged mice	7
X-linked hypophosphatemia, fibroblast growth factor 23 signaling, and craniosynostosis	7
Topology and redescriptions detect multiple alternative biological pathways from clinical phenotypes	7
A metabolism-relevant signature as a predictor for prognosis and therapeutic response in pancreatic cancer	7
Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat	7
Lipocalin-2, S100A8/A9, and cystatin C: Potential predictive biomarkers of cardiovascular complications in COVID-19	7
Nanocarrier-mediated curcumin delivery: An adjuvant strategy for CNS disease treatment	7
The skeleton in a physical world	7
Triterpenoid CDDO-EA inhibits lipopolysaccharide-induced inflammatory responses in skeletal muscle cells through suppression of NF-κB	7
Succinate dehydrogenase complex subunit C: Role in cellular physiology and disease	7
Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia	7
Preface: 2022 International Conference on Neuroprotective Agents	7
Decreased PPP1R3G in pre-eclampsia impairs human trophoblast invasion and migration via Akt/MMP-9 signaling pathway	7
Corrigendum to “CTRP3 protects against uric acid-induced endothelial injury by inhibiting inflammation and oxidase stress in rats”	7
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis	7
Bioactive, full-length parathyroid hormone delivered using an adeno-associated viral vector	7
Antiviral activity of medicinal plant-derived products against SARS-CoV-2	6
What does desmin do: A bibliometric assessment of the functions of the muscle intermediate filament	6
Dietary supplementation with L-leucine reduces nitric oxide synthesis by endothelial cells of rats	6
N-acetylcysteine improves autism-like behavior by recovering autophagic deficiency and decreasing Notch-1/Hes-1 pathway activity	6
Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats	6
Effects of moderate-continuous and high-intensity interval aerobic training on cardiac function of spontaneously hypertensive rats	6
Contusion concomitant with ischemia injury aggravates skeletal muscle necrosis and hinders muscle functional recovery	6
Effects of autoimmune abnormalities on skeletal muscle regeneration after needle puncture in mice	6
Identifying immune subtypes of uterine corpus endometrial carcinoma and a four-paired-lncRNA signature with immune-related lncRNAs	6
Transcriptomic profiling of cerebrospinal fluid identifies ALS pathway enrichment and RNA biomarkers in MND individuals	6
Identification and validation of hub genes in CD5-positive diffuse large B-cell lymphoma	6
Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis	6
Mesenchymal stem cells with p38 mitogen-activated protein kinase interference ameliorate mouse ischemic stroke	6
Epigallocatechin-3-gallate attenuates myocardial fibrosis in diabetic rats by activating autophagy	6
Sex differences in muscle SIRT1 and SIRT3 and exercise + weight loss effects on muscle sirtuins	6
Evolving techniques for reducing phantom limb pain	6
EXPRESSION OF CONCERN: Chondroitin-4-Sulphate Reduced Oxidative Injury in Caerulein-Induced Pancreatitis in Mice: The Involvement of NF-κB Translocation and Apoptosis Activation	6
Decision rules for personalized statin treatment prescriptions over multi-objectives	6
Mouse embryonic stem cells require multiple amino acids	6
Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography	6
Heterogeneity of humoral response patterns in mildly symptomatic, non-hospitalized COVID-19 patients: A one-year longitudinal study	6
CX3CR1 deficiency exacerbates immune-mediated hepatitis by increasing NF-κB-mediated cytokine production in macrophage and T cell	6
TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19	6
Neutrophil extracellular traps contributing to atherosclerosis: From pathophysiology to clinical implications	6
Implications of fibrotic extracellular matrix in diabetic retinopathy	6
Therapeutically leveraging GABAA receptors in cancer	6
Enriched environment as a nonpharmacological neuroprotective strategy	6
Intranasal administration of mitochondria improves spatial memory in olfactory bulbectomized mice	6
A review on photo-mediated ultrasound therapy	6
Single-nucleotide polymorphisms of TLR4 and GAS7 linked to primary open-angle glaucoma among patients of Shenyang, China	6
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients	5
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle	5
Gene expression patterns and related pathways in the hearts of rhesus monkeys subjected to prolonged myocardial ischemia	5
Overall and cancer-specific survival in patients with breast Paget disease: A population-based study	5
4-Octyl itaconate alleviates renal ischemia reperfusion injury by ameliorating endoplasmic reticulum stress via Nrf2 pathway	5
Cyclin D1b induces changes in the macrophage phenotype resulting in promotion of tumor metastasis	5
Weighted gene co-expression network analysis reveals the hub genes associated with pulmonary hypertension	5
Alteration of endothelial permeability ensures cardiomyocyte survival from ischemic insult in the subendocardium of the heart	5
Islet cell encapsulation – Application in diabetes treatment	5
Corrigendum	5
Neonatal sevoflurane exposure induces long-term changes in dendritic morphology in juvenile rats and mice	5
Dietary supplementation with L-citrulline improves placental angiogenesis and embryonic survival in gilts	5
An overview of viral chitinases: General properties and biotechnological potential	5
Unraveling the physiologic paradoxes that underlie exercise prescription for stress fracture prevention	5
Everolimus-induced hyperpermeability of endothelial cells causes lung injury	5
Ultrasound in ocular oncology: Technical advances, clinical applications, and limitations	5
Is type 2 diabetes mellitus another intercellular junction-related disorder?	5
Is graphene the rock upon which new era continuous glucose monitors could be built?	5
Reduced expression of transmembrane protein 43 during cardiac hypertrophy leads to worsening heart failure in mice	5
Recent insights into atherosclerotic plaque cell autophagy	5
Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery	5
Evaluation methodology for deep learning imputation models	5
Retraction Notice	5
Photoacoustic imaging systems based on clinical ultrasound platform	5
Mechanisms maintaining cerebral perfusion during systemic hypotension are impaired in elderly adults	5
Protective effect of astaxanthin on tuberculosis-associated inflammatory lung injury	5
The U.S. Food and Drug Administration, the mechanism of action, and other considerations for cell-based therapy candidates	5
Renal cystic disease in tuberous sclerosis complex	5
Imaging and artificial intelligence for progression of age-related macular degeneration	5
Decellularization of the human urethra for tissue engineering applications	5
Differential expression profile of plasma exosomal microRNAs in chronic rhinosinusitis with nasal polyps	4
Development of a novel purification protocol to isolate and identify brain microglia	4
Metformin and retinal diseases in preclinical and clinical studies: Insights and review of literature	4
Therapeutic strategies to improve liver regeneration after hepatectomy	4
Melatonin pretreatment modulates anti-inflammatory, antioxidant, YKL-40, and matrix metalloproteinases in endotoxemic rat lung tissue	4
Transcriptomic profile of the mechanosensitive ion channelome in human cardiac fibroblasts	4
Risk factors for neonatal VAP: A retrospective cohort study	4
Clinical and genetic investigations in Chinese families with retinitis pigmentosa	4
In vitro comparative evaluation of Tamarix gallica extracts for antioxidant and antidiabetic activity	4
The expression and function of growth hormone secretagogue receptor in immune cells: A current perspective	4
TGFβ1 induces CXCL1 to promote stemness features in lung cancer	4
Calcitriol ameliorates damage in high-salt diet-induced hypertension: Evidence of communication with the gut–kidney axis	4
URNet: System for recommending referrals for community screening of diabetic retinopathy based on deep learning	4