Experimental Biology and Medicine

Article	Citations
Influence of glutamate and GABA transport on brain excitatory/inhibitory balance	79
Detection of severe acute respiratory syndrome coronavirus 2 and influenza viruses based on CRISPR-Cas12a	53
Hypoxic tumor microenvironment: Implications for cancer therapy	51
Cancer and stem cells	51
Going with the grain: Fiber, cognition, and the microbiota-gut-brain-axis	47
Prevalence of class I–III BRAF mutations among 114,662 cancer patients in a large genomic database	41
A mini-review on the effects of COVID-19 on younger individuals	39
The role of extracellular matrix in normal and pathological pregnancy: Future applications of microphysiological systems in reproductive medicine	39
Nitric oxide modulation in neuroinflammation and the role of mesenchymal stem cells	38
Gallic acid enhances reproductive function by modulating oxido-inflammatory and apoptosis mediators in rats exposed to aflatoxin-B1	35
Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects	35
The impact of the COVID-19 infection in dentistry	34
Is periodontal disease a risk factor for developing severe Covid-19 infection? The potential role of Galectin-3	33
Nicorandil inhibits TLR4/MyD88/NF-κB/NLRP3 signaling pathway to reduce pyroptosis in rats with myocardial infarction	31
CD9, a tetraspanin target for cancer therapy?	31
Dysregulation of brain dopamine systems in major depressive disorder	30
An overview of neuroblastoma cell lineage phenotypes andin vitromodels	29
Direct on-the-spot detection of SARS-CoV-2 in patients	28
The amount of cytokine-release defines different shades of Sars-Cov2 infection	28
Breast cancer in sub-Saharan Africa: The current state and uncertain future	28
COVID-19 global pandemic planning: Decontamination and reuse processes for N95 respirators	27
Overdosing on iron: Elevated iron and degenerative brain disorders	26
Exosomes derived from synovial fibroblasts under hypoxia aggravate rheumatoid arthritis by regulating Treg/Th17 balance	26
The effect of ultrasound cavitation on endothelial cells	24
Liquiritigenin decreases tumorigenesis by inhibiting DNMT activity and increasing BRCA1 transcriptional activity in triple-negative breast cancer	24

Endothelin-1 in portal hypertension: The intricate role of hepatic stellate cells	24
Overcoming physiological barriers by nanoparticles for intravenous drug delivery to the lymph nodes	23
Role of sex hormones in lung cancer	23
Role of myokines and osteokines in cancer cachexia	23
Transcriptomic profiles in Parkinson’s disease	23
The multifunctionality of expression systems in Bacillus subtilis: Emerging devices for the production of recombinant proteins	23
Role of inflammatory markers in corona virus disease (COVID-19) patients: A review	23
Imaging and artificial intelligence for progression of age-related macular degeneration	22
Emerging technologies and their impact on regulatory science	22
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction	21
Circulating serum exosomal miR-20b-5p and miR-3187-5p as efficient diagnostic biomarkers for early-stage non-small cell lung cancer	20
12 Survival-related differentially expressed genes based on the TARGET-osteosarcoma database	20
Protease-activated receptor 1 as a potential therapeutic target for COVID-19	20
Photoacoustic imaging systems based on clinical ultrasound platform	19
Therapeutically leveraging GABAA receptors in cancer	19
Secondary hemophagocytic lymphohistiocytosis versus cytokine release syndrome in severe COVID-19 patients	19
Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C)	19
Machine learning in optical coherence tomography angiography	19
Silicon: A neglected micronutrient essential for bone health	19
Angiogenic and anti-inflammatory properties of azadirachtin A improve random skin flap survival in rats	18
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients	18
Innovative approaches for treatment of osteosarcoma	18
Regulation of Th1/Th2 and Th17/Treg by pDC/mDC imbalance in primary immune thrombocytopenia	17
IL-17A is involved in diabetic inflammatory pathogenesis by its receptor IL-17RA	17
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle	17
NAD metabolism in aging and cancer	16
Adipose-derived stem cells in ovarian cancer progression, metastasis, and chemoresistance	16
The “ideal protein” concept is not ideal in animal nutrition	16
Pathology and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)	16
Hypoxic colorectal cancer-secreted exosomes deliver miR-210-3p to normoxic tumor cells to elicit a protumoral effect	16
Tackling rare diseases: Clinical trials on chips	16
SARS-CoV-2 variants: A double-edged sword?	16
The WWOX gene in brain development and pathology	16
Genomic analysis of SARS-CoV-2 reveals local viral evolution in Ghana	16
Metformin and retinal diseases in preclinical and clinical studies: Insights and review of literature	16
A GM1 gangliosidosis mutant mouse model exhibits activated microglia and disturbed autophagy	15
Importance of extracellular vesicles in hypertension	15
Long non-coding RNA IGF2-AS represses breast cancer tumorigenesis by epigenetically regulating IGF2	15
Circulating LIPCAR is a potential biomarker of heart failure in patients post-acute myocardial infarction	15
Chemokine-like factor 1: A promising therapeutic target in human diseases	15
Rapid and ultrasensitive detection of circulating human papillomavirus E7 cell-free DNA as a cervical cancer biomarker	15
Carbon “quantum” dots for bioapplications	15
Functional intrinsic optical signal imaging for objective optoretinography of human photoreceptors	15
Lipocalin-2, S100A8/A9, and cystatin C: Potential predictive biomarkers of cardiovascular complications in COVID-19	15
Calliandra portoricensisameliorates ovarian and uterine oxido-inflammatory responses inN-methyl-N-nitrosourea and benzo[a]pyrene-treated rats	15
Fast intrinsic optical signal correlates with activation phase of phototransduction in retinal photoreceptors	15
FOXM1 activates JAK1/STAT3 pathway in human osteoarthritis cartilage cell inflammatory reaction	15
Whole-genome sequencing as a first-tier diagnostic framework for rare genetic diseases	14
CircFADS2: A potential prognostic biomarker of colorectal cancer	14
WNT signaling in atrial fibrillation	14

Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma	14
Interpretation of anatomic correlates of outer retinal bands in optical coherence tomography	14
Influence of exercise training on diabetic kidney disease: A brief physiological approach	14
Mitophagy promotes the stemness of bone marrow-derived mesenchymal stem cells	13
Osteopontin as a biomarker for COVID-19 severity and multisystem inflammatory syndrome in children: A pilot study	13
Inflammatory response and matrix metalloproteinases in chronic kidney failure: Modulation by adropin and spexin	13
The antifibrotic role of natural killer cells in liver fibrosis	13
Hyperinflammation after anti-SARS-CoV-2 mRNA/DNA vaccines successfully treated with anakinra: Case series and literature review	13
Survival stratification for colorectal cancer via multi-omics integration using an autoencoder-based model	13
Effect of vitamin D3 supplementation on hepatic lipid dysregulation associated with autophagy regulatory AMPK/Akt-mTOR signaling in type 2 diabetic mice	13
Fungal infection risks associated with the use of cytokine antagonists and immune checkpoint inhibitors	13
KDM1A and KDM3A promote tumor growth by upregulating cell cycle-associated genes in pancreatic cancer	13
The use of DNA methylation clock in aging research	13
Inhibitory effect of hydnocarpin D on T-cell acute lymphoblastic leukemia via induction of autophagy-dependent ferroptosis	13
Arbutin ameliorates glucocorticoid-induced osteoporosis through activating autophagy in osteoblasts	13
SNHG1 represses the anti-cancer roles of baicalein in cervical cancer through regulating miR-3127-5p/FZD4/Wnt/β-catenin signaling	13
Microphysiological systems: What it takes for community adoption	13
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions	12
Sickle cell disease as an accelerated aging syndrome	12
Biological evidence to define a vitamin A deficiency cutoff using total liver vitamin A reserves	12
Gene signature and prognostic merit of M6a regulators in colorectal cancer	12
Variable number tandem repeats – Their emerging role in sickness and health	12
Identification of potential lipid biomarkers for active pulmonary tuberculosis using ultra-high-performance liquid chromatography-tandem mass spectrometry	12
Pulmonary gene delivery—Realities and possibilities	12
E2F3 drives the epithelial-to-mesenchymal transition, cell invasion, and metastasis in breast cancer	12
Minireview: Insights into anti-interferon-γ autoantibodies	12
Sigh maneuver protects healthy lungs during mechanical ventilation in adult Wistar rats	12
Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery	12
Irisin induces white adipose tissue browning in mice as assessed by magnetic resonance imaging	12
Hyperinflammation, apoptosis, and organ damage	12
Silencing p53 inhibits interleukin 10-induced activated hepatic stellate cell senescence and fibrotic degradation in vivo	11
Telomere length in different metabolic categories: Clinical associations and modification potential	11
Treatment of osteoporosis with a modified zeolite shows beneficial effects in an osteoporotic rat model and a human clinical trial	11
Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study	11
Clinical applications of 3D normal and breast cancer organoids: A review of concepts and methods	11
YAP activation in melanoma contributes to anoikis resistance and metastasis	11
Acupuncture reduces pain in rats with osteoarthritis by inhibiting MCP2/CCR2 signaling pathway	11
Elevated RUNX1 is a prognostic biomarker for human head and neck squamous cell carcinoma	11
Neferine induces mitochondrial dysfunction to exert anti-proliferative and anti-invasive activities on retinoblastoma	11
The implications of neutrophil extracellular traps in the pathophysiology of atherosclerosis and atherothrombosis	11
Microengineered systems with iPSC-derived cardiac and hepatic cells to evaluate drug adverse effects	11
Delivery of microRNA-21-sponge and pre-microRNA-122 by MS2 virus-like particles to therapeutically target hepatocellular carcinoma cells	11
Treatment and mechanism of fecal microbiota transplantation in mice with experimentally induced ulcerative colitis	11
Telmisartan ameliorates cardiac fibrosis and diastolic function in cardiorenal heart failure with preserved ejection fraction	10
Pre-diabetes and COVID-19, could we be missing the silent killer?	10
H2S attenuates oxidative stress via Nrf2/NF-κB signaling to regulate restenosis after percutaneous transluminal angioplasty	10
OCT imaging of rod mitochondrial respiration in vivo	10
Redox treatment ameliorates diabetes mellitus-induced skin flap necrosis via inhibiting apoptosis and promoting neoangiogenesis	10
Ligustilide counteracts carcinogenesis and hepatocellular carcinoma cell-evoked macrophage M2 polarization by regulating yes-associated protein-mediated interleukin-6 secretion	10
Label-free characterization of collagen fibers in cancerous esophagus tissues using ratiometric nonlinear optical microscopy	10
Antiviral activity of medicinal plant-derived products against SARS-CoV-2	10
The neurovascular extracellular matrix in health and disease	10
Serum-derived exosomes from neurofibromatosis type 1 congenital tibial pseudarthrosis impaired bone by promoting osteoclastogenesis and inhibiting osteogenesis	10
Ultrasound cavitation enhanced chemotherapy: In vivo research and clinical application	10
Management of altered metabolic activity in Drosophila model of Huntington’s disease by curcumin	10
Bacteriophages immunomodulate the response of monocytes	10
Exploring machine learning for audio-based respiratory condition screening: A concise review of databases, methods, and open issues	10
Alternative splicing of leptin receptor overlapping transcript in osteosarcoma	10
Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism	10
Contrast effects of autophagy in the treatment of bladder cancer	10
The role of chest computed tomography in the management of COVID-19: A review of results and recommendations	10
Are insulin-resistance and oxidative stress cause or consequence of aging	10
Animal models of regenerative medicine for biological treatment approaches of degenerative disc diseases	10
COVID-19 global pandemic planning: Performance and electret charge of N95 respirators after recommended decontamination methods	10
Islet cell encapsulation – Application in diabetes treatment	10
Modern approaches on stem cells and scaffolding technology for osteogenic differentiation and regeneration	10
Sounding out the hidden data: A concise review of deep learning in photoacoustic imaging	10
COMMD1 upregulation is involved in copper efflux from ischemic hearts	10
Relationship between hyperglycemia, waist circumference, and the course of COVID-19: Mortality risk assessment	10
Inter-proteomic posttranslational modifications of the SARS-CoV-2 and the host proteins ‒ A new frontier	10
Predictive values of sST2 and IL-33 for heart failure in patients with acute myocardial infarction	9
Histone deacetylases in modulating cardiac disease and their clinical translational and therapeutic implications	9
Blockade of OGFr delays the onset and reduces the severity of diabetic ocular surface complications	9
Pathogenesis and brain functional imaging in nocturnal enuresis: A review	9
Shear type and magnitude affect aortic valve endothelial cell morphology, orientation, and differentiation	9
Increased alpha and beta cell mass during mouse pregnancy is not dependent on transdifferentiation	9
Store-operated calcium entry: Pivotal roles in renal physiology and pathophysiology	9
Apigeninidin-enriched Sorghum bicolor (L. Moench) extracts alleviate Aflatoxin B1-induced dysregulation of male rat hypothalamic-reproductive axis	9
Regulation of 1 and 24 hydroxylation of vitamin D metabolites in the proximal tubule	9
Sickle cell vaso-occlusion: The dialectic between red cells and white cells	9

Iron overload cardiomyopathy: Using the latest evidence to inform future applications	9
Protective effect of exogenous hydrogen sulfide on diaphragm muscle fibrosis in streptozotocin-induced diabetic rats	9
Recent developments in autophagy-targeted therapies in cancer	9
TFPI and FXIII negatively and S100A8/A9 and Cystatin C positively correlate with D-dimer in COVID-19	9
Fetuin-A exerts a protective effect against experimentally induced intestinal ischemia/reperfusion by suppressing autophagic cell death	9
Histone deacetylase-3: Friend and foe of the brain	9
Intranasal administration of mitochondria improves spatial memory in olfactory bulbectomized mice	9
RASL11B gene enhances hyaluronic acid-mediated chondrogenic differentiation in human amniotic mesenchymal stem cells via the activation of Sox9/ERK/smad signals	9
Atherosclerotic lesion-specific copper delivery suppresses atherosclerosis in high-cholesterol-fed rabbits	9
Oral microbiota in human health and disease: A perspective	9
White matter abnormalities in fetal alcohol spectrum disorders: Focus on axon growth and guidance	9
The role of calcium-sensing receptor signaling in regulating transepithelial calcium transport	9
Cell cycle disturbances in mucopolysaccharidoses: Transcriptomic and experimental studies on cellular models	9
Preclinical and clinical studies of bintrafusp alfa, a novel bifunctional anti-PD-L1/TGFβRII agent: Current status	8
Electronic nicotine delivery system-induced alterations in oral health via saliva assessment	8
A novel variant in DMXL2 gene is associated with autosomal dominant non-syndromic hearing impairment (DFNA71) in a Cameroonian family	8
COVID-19 and diabetes: What do we know so far?	8
A novel microRNA-based signature predicts prognosis among nasopharyngeal cancer patients	8
At the dawn of the transcriptomic medicine	8
Classification of salivary bacteriome in asymptomatic COVID-19 cases based on long-read nanopore sequencing	8
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats	8
Is COVID-19-associated cytokine storm distinct from non-COVID-19 secondary hemophagocytic lymphohistiocytosis?	8
Combining contrast-enhanced ultrasound and blood cell analysis to improve diagnostic accuracy of plasma cell mastitis	8
Inhibition of phospholipases suppresses progression of psoriasis through modulation of inflammation	8
Is sweat a possible route of transmission of SARS-CoV-2?	8
Emerging role of N6-methyladenosine RNA methylation in lung diseases	8
Systemic analysis of the expression levels and prognosis of breast cancer-related cadherins	8
Zoledronic acid modulates osteoclast apoptosis through activation of the NF-κB signaling pathway in ovariectomized rats	8
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment	8
Deep learning prediction of attention-deficit hyperactivity disorder in African Americans by copy number variation	8
Three-dimensional segmentation and depth-encoded visualization of choroidal vasculature using swept-source optical coherence tomography	8
Cytosolic protein quality control machinery: Interactions of Hsp70 with a network of co-chaperones and substrates	8
Dysregulation of the OGF–OGFr pathway correlates with elevated serum OGF and ocular surface complications in the diabetic rat	8
Impact of spexin on metabolic diseases and inflammation: An updated minireview	8
Identification of histone acetylation in a murine model of allergic asthma by proteomic analysis	8
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography	8
Mechanisms of disease-associated SINE-VNTR-Alus	7
Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors	7
Pancreatic acinar cells utilize tyrosine to synthesize L-dihydroxyphenylalanine	7
Wogonin, as a potent anticancer compound: From chemistry to cellular interactions	7
Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat	7
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis	7
Lnc-ATG9B-4 aggravates progress of hepatocellular carcinoma through cell proliferation and migration by upregulating CDK5	7
Transcellular routes of blood–brain barrier disruption	7
Analyses of short-chain fatty acids and exhaled breath volatiles in dietary intervention trials for metabolic diseases	7
hsa-miR-607, lncRNA TUG1 and hsa_circ_0071106 can be combined as biomarkers in type 2 diabetes mellitus	7
COVID-19 global pandemic planning: Presence of SARS-CoV-2 fomites in a university hospital setting	7
Altered gene expression in glycolysis–cholesterol synthesis axis correlates with outcome of triple-negative breast cancer	7
Tumor cell anabolism and host tissue catabolism-energetic inefficiency during cancer cachexia	7
Particulate matter inhalation and the exacerbation of cardiopulmonary toxicity due to metabolic disease	7
Recent insights into atherosclerotic plaque cell autophagy	7
Regulation of lymphangiogenesis by extracellular vesicles in cancer metastasis	7
Natural antioxidants attenuate mycolactone toxicity to RAW 264.7 macrophages	7
Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets	7
High atherogenic index of plasma and cardiovascular risk factors among Ghanaian breast cancer patients	7