Cancer Cell

Papers
(The H4-Index of Cancer Cell is 105. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Accelerated approvals: Early-phase success or premature authorization?2019
Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer572
Hand in hand to successful immunotherapy: CD8+ T cells and M1-like macrophages swap the baton559
A stratification system for breast cancer based on basoluminal tumor cells and spatial tumor architecture524
KIT as a therapeutic target in neuroendocrine prostate cancer398
TAMing immunity through an unexpected source393
Efficacy of booster doses in augmenting waning immune responses to COVID-19 vaccine in patients with cancer386
Dynamic circulating tumor DNA during chemoradiotherapy predicts clinical outcomes for locally advanced non-small cell lung cancer patients357
Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer331
Diet-microbiome interactions in cancer328
Characterization of the generic mutant p53-rescue compounds in a broad range of assays327
Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas317
Functional precision oncology: Testing tumors with drugs to identify vulnerabilities and novel combinations295
EGFR-activated myofibroblasts promote metastasis of pancreatic cancer290
KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition288
Spatial profiling technologies illuminate the tumor microenvironment278
Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling269
Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target267
Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity259
Bacteria in metastatic sites: Unveiling hidden players in cancer progression256
B cell heterogeneity in cancer comes of age251
Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma245
High endothelial venules in cancer: Regulation, function, and therapeutic implication244
Neutralization breadth of SARS-CoV-2 viral variants following primary series and booster SARS-CoV-2 vaccines in patients with cancer239
Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer237
T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation234
T cell dynamism and immune-related adverse events234
Enhanced SARS-CoV-2 breakthrough infections in patients with hematologic and solid cancers due to Omicron230
Intratumoral immune triads are required for immunotherapy-mediated elimination of solid tumors229
The aging lung microenvironment awakens melanoma metastases229
Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer227
Cancer vaccines214
Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion211
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin208
A holistic view of cancer206
Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments206
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer203
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer203
Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses203
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer201
Challenges in neoantigen-directed therapeutics195
Gut microbes promote chemoradiotherapy resistance via metabolic cross-feeding193
Tumor-directed dysregulation of erythroid progenitors drives immunosuppressive myeloid cells193
Immunosensitivity cuts across mismatch repair status in colorectal cancer191
Are we ready to look beyond plasma cells in assessing high-risk smoldering myeloma?188
A genetic portrait of metastatic seeds in lung adenocarcinoma187
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma185
Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression185
Revisiting TNM staging for EBV-related nasopharyngeal carcinoma184
Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts183
Evolutionary landscape of clonal hematopoiesis in 3,359 individuals from the general population183
Tumor organoid-originated biomarkers predict immune response to PD-1 blockade177
Integrated single-cell and spatial transcriptomics uncover distinct cellular subtypes involved in neural invasion in pancreatic cancer175
Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation174
Hypoxia inducible factor-1α drives cancer resistance to cuproptosis169
Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics167
Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients161
Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation161
The one-two punch: TIM-3 blockade targets immune and tumor cells to knock out pediatric brain tumors160
Challenges and opportunities for modeling aging and cancer158
Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma156
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer155
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification154
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma153
Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy153
Immunotherapy-activated T cells recruit and skew late-stage activated M1-like macrophages that are critical for therapeutic efficacy149
Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer145
Dissecting bulk transcriptomes of diffuse large B cell lymphoma143
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity143
Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade141
ILC3 plasticity in microbiome-mediated tumor progression and immunotherapy140
Hepatobiliary tumor organoids for personalized medicine: a multicenter view on establishment, limitations, and future directions140
Response-based molecular subtyping—emergence of the third generation of breast cancer subtypes138
Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma138
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma135
A path to translation: How 3D patient tumor avatars enable next generation precision oncology135
Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers134
Recognition of observer effect is required for rigor and reproducibility of preclinical animal studies134
Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells133
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis132
Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD131
Midkine as a driver of age-related changes and increase in mammary tumorigenesis129
Immune determinants of the pre-metastatic niche129
Tumor-infiltrating lymphocytes: A new hope127
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment126
MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells126
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness125
Integrated proteogenomic characterization of glioblastoma evolution125
Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring123
Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1122
Taxanes directly induce T cell cytotoxic extracellular vesicles to eradicate tumor cells120
Risk factors for poor humoral response to primary and booster SARS-CoV-2 vaccination in hematologic and oncological outpatients—COVIDOUT study120
Multiplex computational pathology for treatment response prediction117
T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to squamous cancers115
GDF15 research from bench to bedside115
Firing up neutrophil anti-tumor immunity with cocktails114
Immunosequencing identifies signatures of T cell responses for early detection of nasopharyngeal carcinoma111
The winner takes it all: Competition drives clonal selection in gliomagenesis111
JUPITER-06 establishes immune checkpoint inhibitors as essential first-line drugs for the treatment of advanced esophageal squamous cell carcinoma110
A circular RNA in neuroendocrine carcinomas110
CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma108
Precise patient stratification in esophageal cancer: Biomarkers for immunochemotherapy108
New horizons at the interface of artificial intelligence and translational cancer research106
Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment106
Tumors on different wavelengths105
IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma105
Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer105
Proteogenomic data and resources for pan-cancer analysis105
Effect of neoadjuvant chemoradiotherapy with or without PD-1 antibody sintilimab in pMMR locally advanced rectal cancer: A randomized clinical trial105
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