Cancer Cell

Papers
(The H4-Index of Cancer Cell is 112. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
TAMing immunity through an unexpected source3325
A stratification system for breast cancer based on basoluminal tumor cells and spatial tumor architecture613
A snapshot of the earliest stages of hepatocellular carcinoma554
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression528
Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling512
Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas490
Diet-microbiome interactions in cancer466
Lymphoma accelerates T cell and tissue aging459
Multimodal spatial-omics reveal co-evolution of alveolar progenitors and proinflammatory niches in progression of lung precursor lesions434
IL-36γ armored CAR T cells reprogram neutrophils to induce endogenous antitumor immunity432
Characterization of the generic mutant p53-rescue compounds in a broad range of assays405
Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer389
KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition358
Spatial profiling technologies illuminate the tumor microenvironment349
EGFR-activated myofibroblasts promote metastasis of pancreatic cancer340
Dynamic circulating tumor DNA during chemoradiotherapy predicts clinical outcomes for locally advanced non-small cell lung cancer patients319
Accelerated approvals: Early-phase success or premature authorization?312
Long-range cholinergic input promotes glioblastoma progression310
Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer308
Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth297
Hand in hand to successful immunotherapy: CD8+ T cells and M1-like macrophages swap the baton289
KIT as a therapeutic target in neuroendocrine prostate cancer288
Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses286
Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target285
B cell heterogeneity in cancer comes of age276
Cancer vaccines264
Bacteria in metastatic sites: Unveiling hidden players in cancer progression251
T-Lymphoblastic Lymphoma Cells Express High Levels of BCL2, S1P1, and ICAM1, Leading to a Blockade of Tumor Cell Intravasation243
A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma237
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer231
Enhanced SARS-CoV-2 breakthrough infections in patients with hematologic and solid cancers due to Omicron231
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer230
Challenges in neoantigen-directed therapeutics229
T cell dynamism and immune-related adverse events221
Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma218
Identification of cycling regulatory T cell precursors as conductors of immune escape during breast carcinoma progression213
The aging lung microenvironment awakens melanoma metastases211
When the methylome becomes the microscope211
Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS210
A holistic view of cancer210
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin206
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer204
Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancer204
Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer199
Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity196
Intratumoral immune triads are required for immunotherapy-mediated elimination of solid tumors195
High endothelial venules in cancer: Regulation, function, and therapeutic implication195
Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses194
A genetic portrait of metastatic seeds in lung adenocarcinoma193
Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression190
Are we ready to look beyond plasma cells in assessing high-risk smoldering myeloma?188
Tumor-directed dysregulation of erythroid progenitors drives immunosuppressive myeloid cells186
Gut microbes promote chemoradiotherapy resistance via metabolic cross-feeding186
Revisiting TNM staging for EBV-related nasopharyngeal carcinoma185
Distinct T cell functions enable efficient immunoediting and prevent tumor emergence of developing sarcomas180
Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts180
Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation177
The one-two punch: TIM-3 blockade targets immune and tumor cells to knock out pediatric brain tumors177
Integrated single-cell and spatial transcriptomics uncover distinct cellular subtypes involved in neural invasion in pancreatic cancer176
Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer174
Immunotherapy-activated T cells recruit and skew late-stage activated M1-like macrophages that are critical for therapeutic efficacy174
Challenges and opportunities for modeling aging and cancer172
Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation172
Immunosensitivity cuts across mismatch repair status in colorectal cancer171
Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma165
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma164
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma164
Hypoxia inducible factor-1α drives cancer resistance to cuproptosis163
Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics161
Evolutionary landscape of clonal hematopoiesis in 3,359 individuals from the general population161
Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy161
Targeting STING to generate therapeutic anti-tumor immunity157
Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients157
Circulating tumor DNA as a biomarker in early phase clinical trials155
Response-based molecular subtyping—emergence of the third generation of breast cancer subtypes153
A conserved, terminal, pro-tumor neutrophil population153
Ubiquitin control of cytosolic DNA sets immune responses to DNA damage153
A path to translation: How 3D patient tumor avatars enable next generation precision oncology151
Framework for cancer evolution profiling and interception in colorectal cancer: ASCEND-CRC program150
Knowledge-enhanced pretraining for vision-language pathology foundation model on cancer diagnosis147
Midkine as a driver of age-related changes and increase in mammary tumorigenesis145
Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma145
Characterization of a pathogenic subpopulation of human glioma associated macrophages linked to glioma progression144
Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1144
Interleukin-21 engineering enhances NK cell activity against glioblastoma via CEBPD143
Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers143
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment143
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness142
Tumor-resident Lactobacillus iners confer chemoradiation resistance through lactate-induced metabolic rewiring141
Integrated proteogenomic characterization of glioblastoma evolution141
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis139
Immune determinants of the pre-metastatic niche135
Tumor-infiltrating lymphocytes: A new hope134
Precise patient stratification in esophageal cancer: Biomarkers for immunochemotherapy131
GDF15 research from bench to bedside131
Tumors on different wavelengths130
The winner takes it all: Competition drives clonal selection in gliomagenesis129
A circular RNA in neuroendocrine carcinomas129
Immunosequencing identifies signatures of T cell responses for early detection of nasopharyngeal carcinoma128
Effect of neoadjuvant chemoradiotherapy with or without PD-1 antibody sintilimab in pMMR locally advanced rectal cancer: A randomized clinical trial125
Exercise-induced engagement of the IL-15/IL-15Rα axis promotes anti-tumor immunity in pancreatic cancer125
Tumor-infiltrating bacteria disrupt cancer epithelial cell interactions and induce cell-cycle arrest123
IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma123
Risk factors for poor humoral response to primary and booster SARS-CoV-2 vaccination in hematologic and oncological outpatients—COVIDOUT study122
Taxanes directly induce T cell cytotoxic extracellular vesicles to eradicate tumor cells121
A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies121
CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma120
T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to squamous cancers120
New horizons at the interface of artificial intelligence and translational cancer research119
Proteogenomic data and resources for pan-cancer analysis118
Firing up neutrophil anti-tumor immunity with cocktails117
JYP0322, a highly selective and brain-penetrant ROS1 inhibitor, overcomes ROS1 resistance mutation in NSCLC: The first-in-human phase 1 trial114
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