Cancer Cell

Papers
(The H4-Index of Cancer Cell is 99. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Oxidative Stress in Cancer1244
Conserved pan-cancer microenvironment subtypes predict response to immunotherapy521
The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker497
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities427
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion389
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth385
Engineering CAR-T Cells for Next-Generation Cancer Therapy351
Proteogenomic and metabolomic characterization of human glioblastoma323
The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes312
Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer288
Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments284
Clinical Challenges of Immune Checkpoint Inhibitors283
CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4280
Challenges and Opportunities for Pancreatic Cancer Immunotherapy275
Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer274
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma272
Molecular Subsets in Renal Cancer Determine Outcome to Checkpoint and Angiogenesis Blockade269
Seroconversion rates following COVID-19 vaccination among patients with cancer269
MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate264
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation260
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma255
Progressive immune dysfunction with advancing disease stage in renal cell carcinoma237
Nivolumab Plus Ipilimumab for Metastatic Castration-Resistant Prostate Cancer: Preliminary Analysis of Patients in the CheckMate 650 Trial221
Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells219
Microbiome and cancer218
Antibody response to SARS-CoV-2 vaccines in patients with hematologic malignancies216
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution211
Targeting cell-cycle machinery in cancer210
YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis198
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma194
Identifying and Targeting Human Tumor Antigens for T Cell-Based Immunotherapy of Solid Tumors194
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma190
COVID-19 and Cancer: Current Challenges and Perspectives188
Immunogenicity of SARS-CoV-2 messenger RNA vaccines in patients with cancer186
SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19185
Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial185
Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer185
Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver183
Immunometabolic Interplay in the Tumor Microenvironment181
Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy181
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma177
Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer174
Highly variable SARS-CoV-2 spike antibody responses to two doses of COVID-19 RNA vaccination in patients with multiple myeloma170
Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states170
Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade168
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity166
Single-cell dissection of cellular components and interactions shaping the tumor immune phenotypes in ovarian cancer164
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification163
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer163
Mutant p53 suppresses innate immune signaling to promote tumorigenesis160
Biomolecular Condensates and Cancer158
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations157
Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer156
Effect of ibrutinib with R-CHOP chemotherapy in genetic subtypes of DLBCL155
Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer154
DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity154
The Glioma Stem Cell Model in the Era of Single-Cell Genomics151
Single-Cell Multiomics Sequencing Reveals Prevalent Genomic Alterations in Tumor Stromal Cells of Human Colorectal Cancer145
Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma143
An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence143
Artificial intelligence for clinical oncology142
IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis142
Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma141
Immunomodulation by targeted anticancer agents139
Immune phenotypic linkage between colorectal cancer and liver metastasis137
Integrated Omics of Metastatic Colorectal Cancer136
Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial135
Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer135
Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells134
Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer130
Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site129
Artificial intelligence for multimodal data integration in oncology128
Tumor organoids: Opportunities and challenges to guide precision medicine128
Antibody and T cell immune responses following mRNA COVID-19 vaccination in patients with cancer126
Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma125
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma124
Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity124
Activating a collaborative innate-adaptive immune response to control metastasis124
Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy124
The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth123
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer123
Pan-cancer integrative histology-genomic analysis via multimodal deep learning121
Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer120
Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer118
Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription117
Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms114
Functional precision oncology: Testing tumors with drugs to identify vulnerabilities and novel combinations113
MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway113
Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence111
SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways111
N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation109
Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress109
Dietary Approaches to Cancer Therapy109
The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma108
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment106
Extensive Remodeling of the Immune Microenvironment in B Cell Acute Lymphoblastic Leukemia106
Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance102
Immunogenomic Landscape of Hematological Malignancies101
Melanoma models for the next generation of therapies100
MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage99
The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H199
Targeting pan-essential genes in cancer: Challenges and opportunities99
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