Epilepsy Currents

Article	Citations
Making Up Missed Anti-Seizure Medication Doses: Double or Nothing?	33
Registry-Based Phenotyping to Improve the Diagnosis of Autoimmune Encephalitis	30
SUDEP: A Local Low Pressure [pO2] System Makes It Hard to Breathe	28
Unblock the Block! Preventing Inhibitory Failure to Maintain Inhibitory Restraint	21
Epilepsy Community at an Inflection Point: Translating Research Toward Curing the Epilepsies and Improving Patient Outcomes	18
Let’s Talk About Sex and Juvenile Myoclonic Epilepsy	15
Artificial Intelligence Applications in the Imaging of Epilepsy and Its Comorbidities: Present and Future	15
From Stumbling Blocks to Stepping Stones: Progress in Treating Temporal Lobe Epilepsy With Stem Cell Transplantation	13
Some (Syn)Gaps are Worse than Others: Deciphering The Role of Syngap Isoforms in Excitatory Synaptic Function	12
Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?	11
Deep Thoughts—Predicting Initial Treatment Response in Newly Diagnosed Epilepsy	11
Ripples of Hyperexcitability in Epilepsy, Autism, and Inattention	10
Drinking from the fountain of youth for mTOR-related epilepsy	9
Money Matters: Measuring the Economic Impact of Epilepsy	9
A Human Touch: Hominid-Specific LRRC37B Regulates Axon Initial Segment Excitability	8
Shifting Focus: The “Other” GABAR	7
Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern	6
Efficient diagnosis leads to better care: streamlining epilepsy diagnosis pathways	6
More Than Reels: Cajal-Retzius Cells Become Active	5
To Not Sleep, Perchance to Seize	5
Salty Battle to Sudden Death: Young vs. Old, Brain vs. Heart	5
Get Out the Door: Ambulatory EEG Trumps Routine EEG in the Detection of Interictal Epileptiform Abnormalities After a First Unprovoked Seizure	5
A Cry for Survival? Rhythmic and Periodic EEG Discharges as Treatment Targets Following Cardiac Arrest	5
Frontal Lobe Epilepsy: Bermuda's Triangle	4
Disentangling the Gordian Knot of Drug-Resistant Epilepsy	4

Surviving the Storm—Surviving Status Epilepticus	4
Open Sesame: Door to Enriched Somatic Variants Underlying Sporadic mTLE	4
Midazolam, Ketamine, and Propofol: While We Slept, Others Worked on Anesthetizing Infusions for Refractory Status Epilepticus	4
Shifting Gears in Clinical Trials- Time to Event Analysis: Music to Some Ears	4
The Unconventional Effects of the Ketogenic Diet (KD) in Preclinical Epilepsy	3
Only Hit the Bad Guys: A Gene Therapy Approach to Selectively Silence Highly Active Neurons Reduces Chronic Seizures in Epileptic Mice	3
Illuminating LGI1 Seizure Mechanisms Using Novel Optical Techniques	3
Light, Kindling, Action! Brain-Wide Circuit Changes After Optogenetic Hippocampal Kindling Revealed by Functional Magnetic Resonance Imaging	3
Seizure Detection Devices in Children: One Step Closer	3
No More Tears: Surgical Options and Outcomes in Hypothalamic Hamartomas	3
Mitigating Risk, Optimizing Care: Antiseizure Medications, Pregnancy, and Autism Spectrum Disorder Risk	3
Try, Try Again: Success Rates After Continued Treatment Attempts in Refractory Status Epilepticus	3
Genetic Networks of Drug Resistance in Epilepsy: Outputs of a Computational and Translational Disease Framework	3
Double, Double Toil and Trouble: Recurrent Episodes of Status Epilepticus Are Associated With Increasingly Worse Outcomes	3
Channeling Seizure Control: Optogenetics in Human Brain Slices	3
Attentional Deficits and Absence Epilepsy: A Tale of 2 Interneuronopathies	3
One to Rule Them All: A Unique TAU Therapy for Neurodevelopmental Encephalopathies	3
Women With Epilepsy: Causes for Concern	3
Over the Limit; Long-Term Seizure and Mortality Risk in Alcohol Withdrawal Seizures	3
Debunking the Myth: The Null Effect of Antiseizure Medications on the Functional Outcomes of Acute Symptomatic Seizures	3
Unlocking the Mysteries of Slumber: Unveiling the Intricate Ties Between Sleep, Epilepsy, and Cognition	3
Gaining Awareness of Increasingly Persistent SCN1A Mutations	3
Diagnostic Yield and Treatment Changes After Genetic Testing of Adults With Epilepsy	2
iDISCO Inferno: Mapping Connectivity Changes Following TBI	2
The Interplay Between Epilepsy and Alzheimer’s Disease: A Pas De Deux	2
Epilepsy Surgery: A Story of Diminishing Returns Over Time? Think Differently and Think Again	2
Mechanisms of Neurostimulation for Epilepsy	2
Is Node Disconnection the Key for Improving LITT Outcome?	2
Cannabidiol Keeps Hippocampal Hyperactivity in Check	2
Depression and Epilepsy: The Bidirectional Relation Goes On and On…	2
Harnessing Metabolomics to Advance Epilepsy Research	2
When Encephalitis Burns Out, Are You Left With a Spark?	2
Comprehensive Epilepsy Care: The Key to Cutting Costs and Seizing Better Outcomes	2
Sage Against the Machine: Promise and Challenge of Artificial Intelligence in Epilepsy	2
Detection is Key: Automated Tonic Seizure Detection With a Wearable Device	2
ENVISIONing a critical period to preserve development: communication delays in SCN1A+ dravet syndrome	2
Molecular Layer Heterotopia: Harmless Brain Warts or Ictal Main Force?	2
The BEST Conceivable Way to Talk About Epilepsy Biomarkers	2
Blame it on the Inputs: Overexcited Entorhinal Inputs Drive Dentate Gyrus Hyperexcitability in a Mouse Model of Dravet Syndrome	2
SEEG Radiofrequency Thermocoagulation and Memory: For Now, Avoid the Trap of Overpromising and Underdelivering	2
Genetic Mechanisms Behind Severe Psychotic Reactions to Levetiracetam	2
WITHDRAWN–How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Regis	2
Not So Innocent Bystanders in Focal Cortical Dysplasia	2
Determining the Spread: Potential Biomarkers and Treatment for Seizure-Induced-Spreading Depolarization in a Mouse Model of Genetic Epilepsy	2
Running Out of Breath: The Diminishing Role of Gabapentinoids in Epilepsy	2
Seizures and Cardiac Dysrhythmias: And the Beat (Sometimes) Goes On	2
Epilepsy After Traumatic Brain Injury: A Triple Threat to the Brain—Carpe Diem or Carpe Dementia?	2
Inflammation Emerges as a Sensitizer of a Heat-Responsive Cation Channel	2
An EEG in Time Saves Nine: Predicting Cognitive Decline in Epilepsy	1
Masterminding Hippocampal Circuits by Transplanting Human GABAergic Interneurons to Treat Temporal Lobe Epilepsy	1

Solving the Molecular Basis of the Developmental and Epileptic Encephalopathies: Are We there Yet?	1
Open the Window for the Cure of Dravet	1
Implementing Clinical Practice Guidelines: Considerations for Epileptologists	1
One for All—Can We Have and Do We Want a First-Line Monotherapy for Epilepsy?	1
Watch Out for GATORs: Fasting, Seizures, and Nutrient Sensing	1
Diving Deep for Sleep: How pH and Blood Volume in the Lateral Hypothalamus Impact REM	1
Pregnancy in Epilepsy: Moms Have Risks too	1
Newly Identified KCNA3 Gene Variants Put the “Excite”-ment Back in Kv1.3 Channelopathy	1
Under New Management: Transplanted GABAergic Progenitors Control Adult Neurogenesis	1
Progressive Neuronal Loss in Epilepsy – A Long-Standing Conundrum Finally Resolved?	1
What You Don’t Look for, You Won’t Find: Value of EEG After Clinical Resolution of Convulsive Status Epilepticus	1
Epileptic Neurons Know JAK/STAT3	1
Spreading Depolarization and Seizures: End of the Beginning, or Beginning of the End?	1
Dravet Syndrome as an Example of Precision Medicine in Epilepsy	1
A “Sodium Drug” for Generalized Epilepsy? A Mystery That Still Needs to be Solved	1
The RNS Crystal Ball Sees Seizure Improvement in Your Future With This Medication	1
No Time to Die – Avoidable Death in Epilepsy	1
Et tu, CA2: CA2 Is Hyperexcitable and Controls Seizures in a Mouse Model of Temporal Lobe Epilepsy	1
The 2021 Epilepsy Research Benchmarks—Respecting Core Principles, Reflecting Evolving Community Priorities	1
Brain on Fire: How Brain Infection and Neuroinflammation Drive Worldwide Epilepsy Burden	1
Ictogenesis? That’s Random…..	1
Persistent Underdosing of Benzodiazepines for Status Epilepticus: The Weight Is the Hardest Part	1
The State of Specialized Epilepsy Care in the States: Increased Access, New Tools, but the Same Dismal Underutilization of Epilepsy Surgery	1
Hippocampal Inhibitory Neuron Loss Is Epileptogenic But Not Likely a Sole Cause of Mesial Temporal Lobe Epilepsy (MTLE)	1
Family Ties: Reproductive Decision Making Among Members of Multiplex Epilepsy Families	1
Don’t Get BUM’d Out: Bumetanide May yet Prove Beneficial for Neonatal Seizures	1
Hit by a Smooth CD8: T-Cell Attack on Hippocampal Neurons Triggers Limbic Encephalitis and Epilepsy	1
From the Murky Depths to the Brain: A Tale of a Glowing Protein That Became the Core of a Seizure-Suppressing Molecular Machinery	1
Predicting Pediatric Genetic Epilepsy Through Electronic Medical Records: A Data-Driven Biomarker Discovery Approach	1
It Takes Two to Tango: Channel Interplay Leads to Paradoxical Hyperexcitability in a Loss-of-Function Epilepsy Variant	1
Is MORE better? Accumulating Evidence for ANT DBS in Epilepsy	1
Removing Basal Temporal Language Cortex in Epilepsy Surgery: Short-Term Disruption or Long-Lasting Problem?	1
Focal Seizures Cruise the Callosal Highway	1
Zeroing in on Phenotypes While Also Broadening Our Understanding of KCNT1-Related Epilepsy	1
Do Seizures Damage the Brain ?—Cumulative Effects of Seizures and Epilepsy: A 2025 Perspective	1
Better Together: Building Bridges for Equity in Epilepsy Care	1
Mechanisms of Subiculum Hyperexcitability in Temporal Lobe Epilepsy	1
Through the Lens: Insights Into Sudden Death	1
More is Different in mTORopathies	1
ABCDEF…SUDEP: Action Potential Barrage in (Superior) Colliculus Causes (Spreading) Depolarization Leading to Epilepsy Fatality	1
Leigh has no Brakes: Impaired Inhibition in a Mouse Model of Leigh Syndrome Leads to Enhanced Seizure Sensitivity	1
The Decline of Screening: Psychiatry is Just Not that Simple	1
The ACTH Quandary: Balancing Efficacy and Affordability for Infantile Spasms Treatment	1
Breaking the Synaptic Vesicle Cycle: Mechanistic Insights into Presynaptic Dysfunctions in Epilepsy	1
Can a Mouse Help Us Unravel the Mysteries of CDKL5-Related Epilepsy?	1
AI-nalyzing Mouse Behavior to Combat Epilepsy	1
That’s a Wrap: Could Controlling Activity-Regulated Myelination Prevent Absence Seizures?	1
Navigating Transition to Adulthood in Epilepsy Patients: A Multidisciplinary Approach	1
Connectome the Dots for Presurgical Predictions	1
ENIGMA in ACAPULCO: Machine Learning Localization of Cerebellar Anatomy in Epilepsy	1
Resting But Not Idle: Insights Into Epilepsy Network Suppression From Intracranial EEG	1
Neuromodulation for Refractory Epilepsy	1
The Stigmatizing Impact of Perceived Epilepsy Stigma	1
Lighting the Way to Seizure Cessation: Transcranial Optogenetic Therapies to Stop Seizures in Mouse Models	1
Revoking the Seize Order: Preventing Spontaneous Seizures With AAV in a CLN2 Mouse Model	1
Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication	1
Stop the Lights—Turning Off the Electricity in Tuberous Sclerosis	1
Brain Energy Oscillations–A Possible Explanation for Seizure Periodicity in Epilepsy?	1
Osteoporosis: The Brittle Reality of an Epilepsy Diagnosis	1
KCN Channels “Cue” Up GABA Release from Astrocytes	1
Language and Epilepsy: A Systems Issue	0
Brand Name Versus Generic?	0
Effect of Levetiracetam Use Duration on Overall Survival of Isocitrate Dehydrogenase Wild-Type Glioblastoma in Adults	0
Be a PEACH and Hand Me That Levetiracetam: Seizure Prophylaxis for Spontaneous Intracerebral Hemorrhage	0
Epilepsy-Specific Anxiety: A Potential Clue to the Seizure Onset Zone	0
Is Bigger Better? Exploring the Compensatory Versus Pathological Nature of Amygdala Hypertrophy	0
On the Right Trk: Towards an Effective Treatment for Dravet Syndrome	0
Brake Early: RGS14 in CA2 Limits Seizures and Oxidative Stress After SE	0
Threaded Structure of a Pathological Oblivion	0
Adenosine Makes a Scene	0
Inflammation Unleashed in Viral-Induced Epileptogenesis	0
“In the Name of the Father: Risk to the Offspring From Paternal Exposure to Valproate During Conception”	0
Dopamine Dilemma Overexcites the Hippocampus in Alzheimer's Disease	0
The Benefits of “Spoilt Milk”: Lactic Acid Can Limit Excitability via HCAR1	0
Laminated Pocket Cards, Low Tech, High Yield	0
KIF4 Gene Variant’s Disruption of PARP1 Signaling Increases Anxiety and Seizure Susceptibility	0
Merging Art with Science: A Detection Score for Autoimmune Epilepsy	0
Sleeping High and Getting Lost on the Spiky Road: What Affects Visual Memory in Older Adults With Epilepsy, and What Can We Do About It?	0
The Power of Delphi and Advocacy: Consensus in SCN8A-Related Epilepsy and Neurodevelopmental Disorders	0
Exit Strategy: Balancing the Risks and Rewards of Antiseizure Medication Withdrawal	0

When Considering Supplemental SEEG, Remember the Die is Cast Before the First Implantation	0
Does SARS-CoV-2 Cause Seizures and Epilepsy in COVID-19 via Inflammation or by Direct Infection?	0
Rapid Whole Genome Sequencing: It Is Feasible! When Can We Implement It?	0
Spike Ripples: Hidden Clues to the Mystery of the Epileptogenic Zone	0
Exploring the Cognitive Outcomes of Children Prenatally Exposed to Antiseizure Medications: Mind the Lab	0
Tubers and Tumors Are CLIPped Together in Tuberous Sclerosis Complex	0
Breaking the CoDE of Cognitive Disorders in Epilepsy	0
Any Way You Slice It: Corpus Callosotomy in Pediatric Drug-Resistant Epilepsy	0
Seizing Off This Mortal Coil: A Matter of Epilepsy and Death	0
AIR Hunger—Why Amygdala Seizures Suppress Breathing	0
A Postictal Traffic Jam	0
Too Much of a Good Thing? Cancer Risk and High Dose Folic Acid in Epilepsy	0
Underutilization of Neurodiagnostic Resources in Drug-Resistant Epilepsy	0
Rogue Waves: A Unifying Model of Human Seizure Propagation	0
Anti-Epileptogenesis: Some Roads Lead to Losartan	0
Intellectual Disability and Epilepsy: The High Incidence and the Risks of Status Epilepticus and Sudden Death Require Improved Therapies	0
Overcoming Barriers to Improve Treatments in Epilepsy	0
Neurons Are GIRKed in GNB1 Encephalopathy: Unraveling Pathogenic Mechanisms in a Complex Neurodevelopmental Disorder	0
Cutting-Edge Classification of Focal Cortical Dysplasia for Epilepsy Surgery	0
Of Blobs and Buzzes: Does SISCOM Imaging Actually Help SEEG Planning?	0
Happy Healthy Parents and Babies: Levetiracetam, Lacosamide and Epilepsy Pregnancy Registries	0
Oops!...Glutamate Did it Again	0
A Salt in the Buffer Zone: Potassium Dysregulation Drives Glioma Growth?	0
Out with prolactin, in with neurofilament light and glial fibrillary acidic protein	0
Neuro2D Lies at the Nexus of Autism, Epilepsy, and Intellectual Disabilities	0
Back to the Basics in Predictive Modeling—Predicting Surgical Success	0
MORE Than Meets the Eye: The Evolving Landscape of DBS in Epilepsy	0
DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long Term	0
Late-Onset Epilepsy: A Distinct Entity that Begins and Ends With the Associated Comorbidities	0
Adapt or Die: Seizures Weaken Chemosensory Responses of Retrotrapezoid Nucleus Neurons to Hypercapnia	0
Machine Learning to Address the Enigma of Temporal Lobe Epilepsy Lateralization	0
Suicidality: Once Again, Don’t Blame the Drug Class	0
Communication Breakdown? The Perils and Opportunities of ASM Self-Discontinuation	0
Early MRI in Epilepsy: A Picture Is Worth a Thousand Preventable Seizures	0
Time Is Brain: The Importance of an Accurate SCN1A Prediction Score in the Era of Precision Medicine	0
No Pain, No Gain of Function: Epilepsy-Associated Variants in SCN2A Defy Classification	0
Erratum 22(1), 22(2), 22(3) and 22(4)	0
Stroke and Ischemic Heart Disease With Enzyme-inducing Antiseizure Medications: Time to Change Prescribing Habits	0
It’s Current: NAEC Provides Us With the Recipe to Build a Better Epilepsy Center	0
What Are the Chances That Epilepsy Surgery Will Allow My Child to Come Off Meds? Assessing Pediatric Epilepsy Surgery Outcomes: Data on ASM Freedom	0
Stereo-EEG Planning: Hitting the Target but Missing the Point?	0
Start Low and Go Slow: The General Principle of Managing Older Adults With Epilepsy Finds Robust Support From Frailty	0
Keto Is Not Just for Kids: A Randomized Trial of a Modified Atkins Diet for Adolescents and Adults With Anti-Seizure Medication-Resistant Epilepsy	0
Emotional Blind Spots in Juvenile Myoclonic Epilepsy	0
Adjunctive Use of Cannabidiol: A Joint Action to Patch Up Drug-Resistant Epilepsy	0
A Call to Change Course for Established Epilepsy	0
P2X7 Forges Ahead in Neonatal Hypoxia	0
The Best Things Happen When You Least Expect Them: Responsive Neurostimulation During Low-Risk Brain States is Associated with Improved Long-Term Seizure Suppression	0
Optokindling, GABA Dwindling	0
Suppress Globally or Seize Locally: Cortical Network Activity Explains Seizure Diversity Among Kcnt1 Mutants	0
Ganaxolone: A New Treatment for CDKL5 Deficiency Disorder	0
Comparative Review of Seizure and Cognitive Outcomes in Resective, Ablative, and Neuromodulatory Temporal Lobe Epilepsy Surgery	0
Entering the Era of Personalized Medicine in Epilepsy Through Neuroimaging Machine Learning	0
Sexual and Reproductive Health Counseling: The Sooner the Better	0
Warming Up to the Notion That Febrile Seizures Can Be Associated With Cognitive Impairment	0
Mobilizing a New Era in Lennox-Gastaut Syndrome Treatment and Prevention	0
Yo GABA GABA! Convergent Mechanisms Driven by Gain-of-Function GABRD and Loss-of-Function SLC6A1 Variants Implicate Elevated GABAergic Tone in Generalized Epilepsies	0
A Muddy Crystal Ball for Infantile-Onset Epilepsy Outcomes	0
Keeping up with KCNQ2: A New Model of Epileptic Encephalopathy	0
Imaging Interneuron Impairment in Ictogenesis: A Spatiotemporal Sweet Spot of Seizure Sampling in Scn1a+/−	0
The “Curious Case of Postictal Oxygen Dissipation”: Could ROS Be the Culprit?	0
It’s About Time! Timing in Epilepsy Evaluation and Treatment	0
Are High-Frequency Activities Reliable Biomarkers of the FCDII Lesion?	0
The Voltage-Sensor S4 Rises to the Occasion in KCNQ2 Channel Activation	0
“Worldwide Heterogeneity in Stereo-EEG Theory and Practice: Do all Roads Lead to Rome?”	0
The Crossroads Between Alzheimer's Disease Pathophysiology and Epilepsy	0
Merritt-Putnam Symposium | Developmental and Epileptic Encephalopathies—Current Concepts and Novel Approaches	0
Synergistic Positive Feedback Mechanisms Underlying Seizure Initiation	0
Update in Progress: Cognitive Phenotypes in Temporal Lobe Epilepsy	0
Exploring CITEs of Inflammation in the Human Epilepsy Brain	0
Forgotten Tides: A Novel Strategy for Bayesian Optimization of Neurostimulation	0
Bringing Statistics to the Clinic to Predict the Future: Nomograms for Psychiatric Outcomes of Epilepsy Surgery	0
Cognitive Problems: Epilepsy's Hidden Challenge	0
What do Newborn Granule Cells Do, and When Do They Do It?	0
When Seizures Trigger “Extreme (Cardiac) Makeover”	0
Electroencephalographic Seizure or Electroencephalographic Status Epilepticus in the ICU? Is it Time to Focus Just on Electroencephalographic Status Epilepticus?	0
Somatic Variants and Surgical Epilepsies: Search and You Will Find	0
Out of Sight, Not Yet Out of Reach: Surgical Outcomes in MRI-Negative and Pathology-Negative Epilepsy Patients	0
Machine Learning for Precision Epilepsy Surgery	0
Responding to the Need of the Hour: Natural History Studies	0
When Apnea Turns Terminal: When, How, Why?	0
How Epileptic Spikes Impair Memory	0
Not a Slam-Dunk: Assessing the Role of EEG/fMRI in the Presurgical Evaluation	0
Raptor Preys on mTOR Imbalance in Tuberous Sclerosis	0
Shining a Light: Advancing Health Equity in Overlooked Epilepsy Communities	0
Predicting the Path: How Machine Learning Can Identify Subtypes of Epilepsy and Predict Disease Progression	0
Seize the Day or Let It Slip Away? The Dilemma of Epilepsy Surgery in Older Adults	0
More Genes, Better Outcome?	0
“T” Times: Revisiting the Timing of Neuronal Injury in Status Epilepticus	0
One Intervention for Many: Solving the Challenge of Managing Mental Health Across the Broad Spectrum of Childhood Epilepsy	0
Neuronal Physiology of Generalized Seizures: The 4 Horsemen of Absence Epilepsy	0
Nav1.1gating Against the Current: Ndnf Interneurons Hold Strong in Dravet Syndrome	0
When Non-Promising Findings Also Go From Aquarium to Bedside: The Importance of Rigorous Preclinical Analyses of ASM Candidates	0
In-hospital Management of Status Epilepticus: Does Uniformity Mean Quality?	0
Driving Into the Unknown: ASM Reductions After Intracranial EEG	0