OOIR: Observatory of International Research

Papers

(The TQCC of Epilepsy Currents is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Making Up Missed Anti-Seizure Medication Doses: Double or Nothing?	37
Registry-Based Phenotyping to Improve the Diagnosis of Autoimmune Encephalitis	31
SUDEP: A Local Low Pressure [pO₂] System Makes It Hard to Breathe	29
Unblock the Block! Preventing Inhibitory Failure to Maintain Inhibitory Restraint	24
Let’s Talk About Sex and Juvenile Myoclonic Epilepsy	19
From Stumbling Blocks to Stepping Stones: Progress in Treating Temporal Lobe Epilepsy With Stem Cell Transplantation	18
Deep Brain, Deep Impact: Rethinking Pediatric Epilepsy Treatment With Deep Brain Stimulation of the Centromedian Nucleus	16
Portrait of Epilepsy on the Canvas of Global Health	15
Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern	13
Artificial Intelligence Applications in the Imaging of Epilepsy and Its Comorbidities: Present and Future	13
Efficient diagnosis leads to better care: streamlining epilepsy diagnosis pathways	12
Some (Syn)Gaps are Worse than Others: Deciphering The Role of Syngap Isoforms in Excitatory Synaptic Function	11
Drinking from the fountain of youth for mTOR-related epilepsy	10
Magnetic Resonance Imaging in Status Epilepticus: Useful Scrying Board or Expensive Stopwatch?	10
Ripples of Hyperexcitability in Epilepsy, Autism, and Inattention	10
Money Matters: Measuring the Economic Impact of Epilepsy	9
Shifting Focus: The “Other” GABAR	8
A Human Touch: Hominid-Specific LRRC37B Regulates Axon Initial Segment Excitability	8
Deep Thoughts—Predicting Initial Treatment Response in Newly Diagnosed Epilepsy	7
Salty Battle to Sudden Death: Young vs. Old, Brain vs. Heart	6
To Not Sleep, Perchance to Seize	5
Frontal Lobe Epilepsy: Bermuda's Triangle	5
Open Sesame: Door to Enriched Somatic Variants Underlying Sporadic mTLE	5
More Than Reels: Cajal-Retzius Cells Become Active	5
A Cry for Survival? Rhythmic and Periodic EEG Discharges as Treatment Targets Following Cardiac Arrest	5

Get Out the Door: Ambulatory EEG Trumps Routine EEG in the Detection of Interictal Epileptiform Abnormalities After a First Unprovoked Seizure	5
Midazolam, Ketamine, and Propofol: While We Slept, Others Worked on Anesthetizing Infusions for Refractory Status Epilepticus	4
No More Tears: Surgical Options and Outcomes in Hypothalamic Hamartomas	4
Gaining Awareness of Increasingly Persistent SCN1A Mutations	4
Over the Limit; Long-Term Seizure and Mortality Risk in Alcohol Withdrawal Seizures	4
Shifting Gears in Clinical Trials- Time to Event Analysis: Music to Some Ears	4
One to Rule Them All: A Unique TAU Therapy for Neurodevelopmental Encephalopathies	4
Surviving the Storm—Surviving Status Epilepticus	4
Quiet, Please—The Brain is Buzzing: Levetiracetam and the Paradox of (Fast) Ripples in Alzheimer's Disease	4
The Unconventional Effects of the Ketogenic Diet (KD) in Preclinical Epilepsy	4
Women With Epilepsy: Causes for Concern	3
Illuminating LGI1 Seizure Mechanisms Using Novel Optical Techniques	3
Unlocking the Mysteries of Slumber: Unveiling the Intricate Ties Between Sleep, Epilepsy, and Cognition	3
Channeling Seizure Control: Optogenetics in Human Brain Slices	3
WITHDRAWN–How to Help Your Patients Enroll in the New-Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES) Family Registry, and Other Rare Epilepsy Regis	3
Genetic Networks of Drug Resistance in Epilepsy: Outputs of a Computational and Translational Disease Framework	3
Double, Double Toil and Trouble: Recurrent Episodes of Status Epilepticus Are Associated With Increasingly Worse Outcomes	3
Only Hit the Bad Guys: A Gene Therapy Approach to Selectively Silence Highly Active Neurons Reduces Chronic Seizures in Epileptic Mice	3
Attentional Deficits and Absence Epilepsy: A Tale of 2 Interneuronopathies	3
Dissecting the Fatal Seizure: The Importance of Forebrain Neurons in SUDEP	3
Light, Kindling, Action! Brain-Wide Circuit Changes After Optogenetic Hippocampal Kindling Revealed by Functional Magnetic Resonance Imaging	3
Seizure Detection Devices in Children: One Step Closer	3
Mitigating Risk, Optimizing Care: Antiseizure Medications, Pregnancy, and Autism Spectrum Disorder Risk	3
Two Halves Make a Whole SCN1A	3
Try, Try Again: Success Rates After Continued Treatment Attempts in Refractory Status Epilepticus	3
Debunking the Myth: The Null Effect of Antiseizure Medications on the Functional Outcomes of Acute Symptomatic Seizures	3
New Neurons, Fewer Seizures: Environmental Enrichment Strengthens Brain Circuits	3
Not So Innocent Bystanders in Focal Cortical Dysplasia	3
Genetic Mechanisms Behind Severe Psychotic Reactions to Levetiracetam	2
Detection is Key: Automated Tonic Seizure Detection With a Wearable Device	2
Comprehensive Epilepsy Care: The Key to Cutting Costs and Seizing Better Outcomes	2
Mechanisms of Neurostimulation for Epilepsy	2
Inflammation Emerges as a Sensitizer of a Heat-Responsive Cation Channel	2
Cannabidiol Keeps Hippocampal Hyperactivity in Check	2
Molecular Layer Heterotopia: Harmless Brain Warts or Ictal Main Force?	2
ENVISIONing a critical period to preserve development: communication delays in SCN1A+ dravet syndrome	2
Diagnostic Yield and Treatment Changes After Genetic Testing of Adults With Epilepsy	2
iDISCO Inferno: Mapping Connectivity Changes Following TBI	2
How Soon is Soon Enough? Consideration of Timing and Disease Etiology for microRNAs in Epilepsy	2
Sage Against the Machine: Promise and Challenge of Artificial Intelligence in Epilepsy	2
Determining the Spread: Potential Biomarkers and Treatment for Seizure-Induced-Spreading Depolarization in a Mouse Model of Genetic Epilepsy	2
Running Out of Breath: The Diminishing Role of Gabapentinoids in Epilepsy	2
Harnessing Metabolomics to Advance Epilepsy Research	2
A Case of the “Spinnies”: Vestibular Epilepsy	2
Decomposing SV2A Function and Dysfunction one Neuron at a Time	2
When Encephalitis Burns Out, Are You Left With a Spark?	2
The Interplay Between Epilepsy and Alzheimer’s Disease: A Pas De Deux	2
SEEG Radiofrequency Thermocoagulation and Memory: For Now, Avoid the Trap of Overpromising and Underdelivering	2
Epilepsy Surgery: A Story of Diminishing Returns Over Time? Think Differently and Think Again	2
Epilepsy Care in the Real World of Multiple Medical Considerations	2

Seizures and Cardiac Dysrhythmias: And the Beat (Sometimes) Goes On	2
Depression and Epilepsy: The Bidirectional Relation Goes On and On…	2
Blame it on the Inputs: Overexcited Entorhinal Inputs Drive Dentate Gyrus Hyperexcitability in a Mouse Model of Dravet Syndrome	2
Aurea Mediocritas: mTOR Abides the Golden Mean	2
ENIGMA in ACAPULCO: Machine Learning Localization of Cerebellar Anatomy in Epilepsy	1
Prepregnancy Education: A Gap in Care for All	1
Leigh has no Brakes: Impaired Inhibition in a Mouse Model of Leigh Syndrome Leads to Enhanced Seizure Sensitivity	1
An EEG in Time Saves Nine: Predicting Cognitive Decline in Epilepsy	1
Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication	1
KCN Channels “Cue” Up GABA Release from Astrocytes	1
Breaking the Synaptic Vesicle Cycle: Mechanistic Insights into Presynaptic Dysfunctions in Epilepsy	1
Dravet Syndrome as an Example of Precision Medicine in Epilepsy	1
Hippocampal Inhibitory Neuron Loss Is Epileptogenic But Not Likely a Sole Cause of Mesial Temporal Lobe Epilepsy (MTLE)	1
More is Different in mTORopathies	1
AI-nalyzing Mouse Behavior to Combat Epilepsy	1
The BEST Conceivable Way to Talk About Epilepsy Biomarkers	1
Revoking the Seize Order: Preventing Spontaneous Seizures With AAV in a CLN2 Mouse Model	1
Zeroing in on Phenotypes While Also Broadening Our Understanding of KCNT1-Related Epilepsy	1
Brain Energy Oscillations–A Possible Explanation for Seizure Periodicity in Epilepsy?	1
Diving Deep for Sleep: How pH and Blood Volume in the Lateral Hypothalamus Impact REM	1
REVing up the Brain: A Mechanism Driving Seizure Timing	1
Predicting Pediatric Genetic Epilepsy Through Electronic Medical Records: A Data-Driven Biomarker Discovery Approach	1
What You Don’t Look for, You Won’t Find: Value of EEG After Clinical Resolution of Convulsive Status Epilepticus	1
Emergency: Lack of Seizure Rescue Preparedness	1
Lighting the Way to Seizure Cessation: Transcranial Optogenetic Therapies to Stop Seizures in Mouse Models	1
Epileptic Neurons Know JAK/STAT3	1
Brain on Fire: How Brain Infection and Neuroinflammation Drive Worldwide Epilepsy Burden	1
The RNS Crystal Ball Sees Seizure Improvement in Your Future With This Medication	1
The State of Specialized Epilepsy Care in the States: Increased Access, New Tools, but the Same Dismal Underutilization of Epilepsy Surgery	1
Spreading Depolarization and Seizures: End of the Beginning, or Beginning of the End?	1
Osteoporosis: The Brittle Reality of an Epilepsy Diagnosis	1
The Many Faces of Juvenile Myoclonic Epilepsy	1
From the Murky Depths to the Brain: A Tale of a Glowing Protein That Became the Core of a Seizure-Suppressing Molecular Machinery	1
Implementing Clinical Practice Guidelines: Considerations for Epileptologists	1
Focal Seizures Cruise the Callosal Highway	1
Can a Mouse Help Us Unravel the Mysteries of CDKL5-Related Epilepsy?	1
It Takes Two to Tango: Channel Interplay Leads to Paradoxical Hyperexcitability in a Loss-of-Function Epilepsy Variant	1
Watch Out for GATORs: Fasting, Seizures, and Nutrient Sensing	1
Is Node Disconnection the Key for Improving LITT Outcome?	1
Under New Management: Transplanted GABAergic Progenitors Control Adult Neurogenesis	1
The ACTH Quandary: Balancing Efficacy and Affordability for Infantile Spasms Treatment	1
Does Deep Brain Stimulation Work in Lennox-Gastaut Syndrome? Well…it Depends	1
ABCDEF…SUDEP: Action Potential Barrage in (Superior) Colliculus Causes (Spreading) Depolarization Leading to Epilepsy Fatality	1
Evaluation, Diagnosis, and Treatment of Concomitant Movement Disorders in Genetic Epilepsies	1
Pregnancy in Epilepsy: Moms Have Risks too	1
Inclusivity in Epilepsy Care: Navigating the Complex Nature of Seizure Disorders in People Undergoing Gender-Affirming Care	1
Neuromodulation for Refractory Epilepsy	1
No Time to Die – Avoidable Death in Epilepsy	1
The Midline Thalamus: The New Kid in Town for Absence Seizure Therapy	1
Do Seizures Damage the Brain ?—Cumulative Effects of Seizures and Epilepsy: A 2025 Perspective	1
Through the Lens: Insights Into Sudden Death	1
“Fasting? Not too Fast”; a Clinical Insight into the Impact of Fasting on Seizure Control in Patients with Epilepsy	1
Solving the Molecular Basis of the Developmental and Epileptic Encephalopathies: Are We there Yet?	1
Masterminding Hippocampal Circuits by Transplanting Human GABAergic Interneurons to Treat Temporal Lobe Epilepsy	1
Rebuilding the Tower of Babel: The Current Landscape and Emerging Opportunities in DEE-SWAS	1
Connectome the Dots for Presurgical Predictions	1
Open the Window for the Cure of Dravet	1
Better Together: Building Bridges for Equity in Epilepsy Care	1
One for All—Can We Have and Do We Want a First-Line Monotherapy for Epilepsy?	1
That’s a Wrap: Could Controlling Activity-Regulated Myelination Prevent Absence Seizures?	1
Epilepsy After Traumatic Brain Injury: A Triple Threat to the Brain—Carpe Diem or Carpe Dementia?	1
Newly Identified KCNA3 Gene Variants Put the “Excite”-ment Back in Kv1.3 Channelopathy	1
Ictogenesis? That’s Random…..	1
Furthering the Evidence of Comorbid Psychiatric Disorders in Pediatric Patients With Psychogenic Nonepileptic Seizures	1
Mechanisms of Subiculum Hyperexcitability in Temporal Lobe Epilepsy	1
Resting But Not Idle: Insights Into Epilepsy Network Suppression From Intracranial EEG	1
Is MORE better? Accumulating Evidence for ANT DBS in Epilepsy	1
The Stigmatizing Impact of Perceived Epilepsy Stigma	1
Et tu, CA2: CA2 Is Hyperexcitable and Controls Seizures in a Mouse Model of Temporal Lobe Epilepsy	1
Navigating Transition to Adulthood in Epilepsy Patients: A Multidisciplinary Approach	1