Vascular Pharmacology

Article	Citations
The transfer of gut microbiota/metabolites from children to mice affects cardiometabolic development and induces sex-dimorphism in recipients	115
Prevalence of antiphospholipid antibodies in COVID-19 patients: A meta-analysis	78
Graphical abstract TOC	48
Biobanks: The unmet need in heart failure management	40
Graphical abstract TOC	32
Therapy and guideline adherence at a multidisciplinary hypertension clinic: A prospective, observational study	31
Corrigendum to “Elucidating the crosstalk between endothelial-to-mesenchymal transition (EndoMT) and endothelial autophagy in the pathogenesis of atherosclerosis” [Vascular Pharmacology 155 (2024) 107	29
Patterns of medication use and potential drug-drug interactions in post-PCI patients: A study from Iran	29
Molecular mechanisms of flavonoids in myocardial ischemia reperfusion injury: Evidence from in-vitro and in-vivo studies	28
ASPYRE-1 study: An Italian multicenter prospective study on pulmonary hypertension modality of death and validation of REVEAL risk score	26
The MEK-ERK-Egr-1 axis and its regulation in cardiovascular disease	24
Editorial Board	23
Animal experimental models of ischemic limbs – A systematic review	23
Prevention of cardiovascular complications in elderly cancer patients	23
Editorial Board	22
Diabetes and vascular disease: New therapeutic avenues	22
Nebivolol in the therapeutic landscape of heart failure: Mechanisms and clinical outcomes	20
A random shuffle method to expand a narrow dataset: A heart failure cohort example	19
Doxorubicin-induced cardiotoxicity enhance SARS-CoV-2 infection susceptibility in human cardiomyocytes	19
Exploiting endothelial functions in bone regenerative medicine	18
Optical stimulation of endothelial colony forming cells plated on light-sensitive conjugated polymers induces a TRPV1-mediated increase in intracellular Ca2+ concentration	18
Changes in arterial myocyte excitability induced by subarachnoid hemorrhage in a rat model	18
Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease	17
Interaction of FOXO1 and SUMOylated PPARγ1 induced by hyperlipidemia and hyperglycemia favors vascular endothelial insulin resistance and dysfunction	17
Adipsin in the pathogenesis of cardiovascular diseases	17

Hemodynamic markers: CFD-based prediction of cerebral aneurysm rupture risk	16
The future of group 2 pulmonary hypertension: Exploring clinical trials and therapeutic targets	16
Global and endothelial G-protein coupled receptor 75 (GPR75) knockout relaxes pulmonary artery and mitigates hypoxia-induced pulmonary hypertension	16
Indobufen versus aspirin in patients with indication for antiplatelet therapy: A systematic review and meta-analysis	16
MicroRNAs and their regulators: Potential therapeutic targets in pulmonary arterial hypertension	16
A novel multidisciplinary approach in an LMNA-mutated patient: the importance of considering the overall clinical picture for the early diagnosis	15
Contents continued	15
Graphical abstract TOC	15
Graphical abstract TOC	15
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro	14
Deleterious effects of levamisole, a cocaine adulterant, in rabbit aorta	14
Real-world observational study on pulmonary arterial hypertension: Italian cohort treated with macitentan and/or selexipag as a part of a combination treatment (INSPECTIO)	14
Novel NLRP3 inflammasome inhibitors INF150 and INF195 attenuate isoproterenol-induced hypertrophy in H9c2 rat cardiac myoblast	13
Graphical abstract TOC	13
Circulating osteonectin predicts postural imbalance and cardiac dysfunction in heart failure	13
Dynamic co-culture of endothelial and smooth muscle cells as a platform for pathophysiological investigations of vascular calcifications	13
Targeting the Ca2+ signaling toolkit as an alternative strategy to mitigate SARS-CoV-2-induced cardiovascular adverse events	13
Trimethylamine N-oxide (TMAO) impact on endothelial dysfunction: An in vitro study using bovine aortic endothelial cells	13
Sexual dimorphism in aortic aneurysm: A review of the contributions of sex hormones and sex chromosomes	12
Myocardial energy balance and metabolism as causes of myocardial ischemia	12
Corrigendum to “Non-coding RNAs regulate angiogenic processes” [Vascular pharmacology 133–134 (2020) 106778]	12
Editorial Board	12
The use of specific antihypertensive medication and skin cancer risk: A systematic review of the literature and meta-analysis	12
Angina pectoris 2023: With and without obstructive coronary artery disease: Epidemiology, diagnosis, prognosis, and treatment	12
Interplay between CD28 and PD-1 in T cell immunotherapy	12
Clinical outcomes and safety of sotatercept in pulmonary arterial hypertension: A systematic review and meta-analysis of randomized controlled trials	12
Bruton's Tyrosine Kinase inhibition by Acalabrutinib does not affect early or advanced atherosclerotic plaque size and morphology in Ldlr mice	12
3-methoxycatechol causes vasodilation likely via KV channels: ex vivo, in silico docking and in vivo study	12
The diverging roles of insulin-like growth factor binding proteins in pulmonary arterial hypertension	11
Clinical characteristics and five-year outcomes in a prospective Russian real-world heart failure cohort	11
Brain natriuretic peptide as a potential predictor of hemorrhagic transformation in acute ischemic stroke patients with successful endovascular recanalization: A two-center retrospective cohort study	11
Editorial Board	11
Therapeutic perspective on cardiomyopathy and heart failure in older adults through the lens of chronic inflammation	11
Sodium nitroprusside: A comprehensive systematic review of its role across various clinical settings	11
Inflammation and the pathogenesis of atherosclerosis	11
Zinc alpha 2-glycoprotein associates with features of plaque stability in patients with carotid atherosclerosis	10
Istaroxime follow-on compounds: A new class of selective SERCA2a activators for chronic heart failure treatment	10
Long-term dietary n3 fatty acid prevents aging-related cardiac diastolic and vascular dysfunction	10
Graphical abstract TOC	10
A treatment algorithm for ischemic cardiomyopathy	10
The role of histone modifications in pulmonary hypertension: From mechanisms to therapeutic targets	10
Effects of simvastatin treatment on leptomeningeal collateral vessels: resistance, number and diameter	10
The influence of environmental hypoxia on the goldfish (Carassius auratus) heart: From functional responses to mitochondrial molecular mechanisms	10
Vascular diameter determines sensitivity to soluble guanylate cyclase activation in human mesenteric and renal arteries	10
Association of MMP9 with adverse features of plaque progression and residual inflammatory risk in patients with chronic coronary syndrome (CCS)	10
Comparative analysis of antiproliferative and vasodilator effects of drugs for pulmonary hypertension: Extensive in vitro study in rats and human	10
Relevance of real-time analyzers to determine mitochondrial quality in endothelial cells and oxidative stress in preeclampsia	9
Resolvin D2 limits senescent cell accumulation in atherosclerotic plaques	9
Plasma exosomes after PCI in non-diabetic STEMI patients fed barley beta-D-glucan-enriched pasta reduce oxidative stress-induced endothelial cell senescence	9
Empagliflozin decreases ageing-associated arterial stiffening and vascular fibrosis under normoglycemic conditions	9

Immune response following transcatheter aortic valve procedure	9
Roles of endothelial and smooth muscle cell dysfunction and vasa vasorum in vasomotor disorders in ischemia with no obstructive coronary artery disease	9
GYY4137, a hydrogen sulfide donor, protects against endothelial dysfunction in porcine coronary arteries exposed to myeloperoxidase and hypochlorous acid	9
The chemokine receptor CXCR4 and its ligand CXCL12 (SDF-1) localize to ependymal cilia in brain ventricles	9
Advancements in non-invasive hyperspectral imaging: Mapping blood oxygen levels and vascular health for clinical and research applications	9
Graphical abstract TOC	8
The role of the endothelium in long COVID	8
N6-methyladenosine (m6A) post-transcriptional modification regulation of mRNA, an overlooked therapeutic opportunity to leverage mRNA processing in vascular smooth muscle cells	8
Multi-omics identification of quantitative trait loci associated with vascular pathogenesis and diagnostic potential in chronic venous disease	8
Editorial Board	8
PI3KC2α: A novel key player in cardiac contractility and DOX-induced cardiotoxicity?	8
CaMKIIδ splice variants differentially regulate vascular smooth muscle cell motility	8
Challenges facing the clinical translation of cardioprotection: 35 years after the discovery of ischemic preconditioning	8
The selective deletion of tyrosyne hydroxylase gene in the endothelium affects cardiovascular function	8
Bioactive lipids improve serum HDL and PON1 activities in coronary artery disease patients: Ex-vivo study	8
Endothelial leptin receptor is dispensable for leptin-induced sympatho-activation and hypertension in male mice	8
Amyloid-β: A potential mediator of aging-related vascular pathologies	8
MELAS syndrome: Insights into cardiac mechanics	8
Catestatin as a key attenuator of cardiac inflammation in hypertension: Role of macrophage immunosuppression	8
Graphical abstract TOC	7
Extracellular stiffness as a determinant of cardiac dysfunction in Duchenne's muscular dystrophy: A study on human iPSC-derived cardiomyocytes	7
Is remote conditioning cardioprotection temperature dependent?	7
Sodium nitroprusside for advanced heart failure. A metanalysis of literature data	7
The life cycle of a capillary: Mechanisms of angiogenesis and rarefaction in microvascular physiology and pathologies	7
From cine-MRI to computational models of blood flow within the heart	7
Effects of mavacamten in human myocardium from hypertrophic obstructive cardiomyopathy (HOCM) patients: A comparison with disopyramide	7
The short-chain fatty acid butyrate accelerates vascular calcification via regulation of histone deacetylases and NF-κB signaling	7
Endothelial dysfunction in acute and long standing COVID−19: A prospective cohort study	7
Melatonin treatment during chronic hypoxic gestation improves neonatal cerebrovascular function	7
Optimal medical therapy vs revascularization in chronic coronary syndromes: Does ISCHEMIA move the needle toward or away from revascularization??	7
Graphical abstract TOC	7
Editorial Board	7
Risk stratification of patients with SARS-CoV-2 by tissue factor expression in circulating extracellular vesicles	7
Exploring bradykinin: A common mediator in the pathophysiology of sepsis and atherosclerotic cardiovascular disease	7
An intrinsic mechanism of metabolic resilience influences the cardiac response to stress	6
Emerging therapies in dyslipidaemias	6
Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: Dissecting the role of cardiac alternans in terminating rapid rhythms	6
Empagliflozin restores autophagy and attenuates ponatinib-induced cardiomyocyte senescence and death	6
Emerging role of the adaptive immunity in aortic aneurysm and dissection	6
Macrophage-mediated downregulation of lncRNA Carmn in mouse abdominal aortic aneurysm	6
Matrix metalloproteinases in aortic dissection	6
Untargeted metabolomic profiling reveals mTORC1-dependent regulation of amino acid utilization in lymphatic endothelial cells	6
Beta-blockers in pulmonary arterial hypertension: Time for a second thought?	6
Contents continued	6
Stay connected: The myoendothelial junction proteins in vascular function and dysfunction	6
Graphical abstract TOC	6
Elucidating emerging signaling pathways driving endothelial dysfunction in cardiovascular aging	6
Myocardin related transcription factor and galectin-3 drive lipid accumulation in human blood vessels	5
Different gene expression patterns between mouse and human brain pericytes revealed by single-cell/nucleus RNA sequencing	5
Graphical abstract TOC	5
Graphical abstract TOC	5
Assessing the impact of air pollution on human embryonic cardioids using innovative longitudinal monitoring and machine learning	5
Understanding the pathobiology of intermediate filaments to curb acute and chronic cardiac dysfunction	5
Frataxin deficiency disrupts mitochondrial respiration and pulmonary endothelial cell function	5
Palmitate-induced cardiac lipotoxicity is relieved by Quercetin and its novel acetylated derivative Q2 through inhibition of oxidative stress and inflammation	5
The crosstalk between lipopolysaccharide-induced septic myocardial dysfunction and cardiac lipotoxicity: Toll like receptor 4 as common target of the novel cardioprotective peptide cateslytin	5
Endothelial-to-mesenchymal transition gene signature derived from single-cell transcriptomics of human atherosclerotic tissue associates with stable plaque histological characteristics	5
An AI and Statistical Shape Analysis combined framework to extract features in complex cardiovascular structures	5
Apoptosis signal-regulating kinase-1 regulates thrombin-induced endothelial permeability	5
LncRNA MYOSLID contributes to PH via targeting BMPR2 signaling in pulmonary artery smooth muscle cell	5
Emerging effects of non-coding RNA in vascular endothelial cells during strokes	5
Aging, sex and NLRP3 inflammasome in cardiac ischaemic disease	5
RNA-seq and ChIP-seq reveal microplastics induce endothelial-mesenchymal transition via HK2-mediated histone lactylation in pulmonary hypertension	4
Right Ventricular-Pulmonary Arterial Coupling and Exercise-induced Pulmonary Congestion in Heart Failure with Reduced and Mildly-reduced Ejection Fraction	4
The pathophysiology of heme in the vascular system	4
Geneless optomodulation of cardiomyocytes membrane potential by sarcolemma-targeted azobenzene photoswitches	4
Editorial Board	4
Doxycycline induces mitochondrial dysfunction in aortic smooth muscle cells	4
Antibody-mediated PCSK9 neutralization worsens outcome after bare-metal stent implantation in mice	4
Mediterranean G6PD variant rats are protected from Angiotensin II-induced hypertension and kidney damage, but not from inflammation and arterial stiffness	4
Macrophages release miRNAs in response to Doxorubicin with a potential role in indirect cardiac damage	4
Explosive discovery, surprising future: The extraordinary journey of nitroglycerin, nitroderivatives and nitric oxide	4
Prolonged L-NAME exposure changes the vasodilator factor from NO to H2O2 in human arterioles in response to A23187	4
Epitranscriptomics in atherosclerosis: Unraveling RNA modifications, editing and splicing and their implications in vascular disease	4
The non-vitamin K antagonist oral anticoagulants in atrial fibrillation patients with high-normal renal function – A systematic review	4
Plaque histological characteristics in individuals with sudden coronary death	4
Vasorelaxant effects of 3-methoxycatechol are not via direct activation of voltage-gated potassium channels	4
Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: Novel targets for therapy	4
Chronic venous insufficiency and cardiovascular risk: Marker or bystander?	4
The hydroxamic acid derivative YPX-C-05 alleviates hypertension and vascular dysfunction through the PI3K/Akt/eNOS pathway	4

Macrophages participate in doxorubicin-induced cardiac damage	4
Graphical abstract TOC	3
Local hemodynamics effects of ischemic preconditioning on non-fatiguing voluntary contractions	3
Mast cells participate in smooth muscle cell reprogramming and atherosclerotic plaque calcification	3
Sex-based variability in cardiac electromechanical properties: Insights into arrhythmia susceptibility and protection	3
Contents continued	3
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Functional characterization of human IL-8 in vascular stenosis using a novel humanized transgenic mouse model	3
Characterization of the PLN-R14Del mutation in hiPSC-derived cardiomyocytes	3
Long-term effects of regular intake of barley beta glucan-containing pasta on left ventricular function in non-diabetic STEMI patients: The Cuore Sano study	3
Electrophysiological effects of estrogen on hiPSC-derived cardiomyocytes of a patient affected by estrogen-sensitive Long-QT Syndrome Type 2	3
17β-Estradiol-mediated modulation of Notch1 in murine macrophage cell line RAW 264.7	3
Comment on “Vascular diameter determines sensitivity to soluble guanylate cyclase activation in human mesenteric and renal arteries” [Lubomirov et al., Vascular pharmacology 160 (2025) 107515]	3
Sex differences in vascular endothelial function related to acute and long COVID-19	3
Sex-related differential susceptibility to ponatinib-induced cardiotoxicity and its relationship to modulation of Notch signaling in a murine model	3
Assessing the peripheral effect of ischemic preconditioning using electrically-stimulated contraction of the adductor pollicis	3
Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury	3
Association of serum 25-hydroxyvitamin D3 levels with carotid artery intima-media thickness and carotid atherosclerotic plaques in smokers	3
Studying exosome fingerprint in COVID 19 patients using MALDI-TOF	3
The role of sinoatrial node heterogeneity in atrial driving and arrhythmia	3
Prestroke barley beta-D-glucan supplementation protects heart and brain from consequences of ischemic stroke regardless of caloric restriction	3
Retraction notice to “Randomized controlled trial of rivaroxaban versus warfarin in the management of acute non-neoplastic portal vein thrombosis” [Vascular Pharmacology 113 (2019) 86-91]	3
MCU-dependent mitochondrial calcium uptake-induced mitophagy contributes to apelin-13-stimulated VSMCs proliferation	3
Chronic thromboembolic disease: Association with exercise-induced pulmonary hypertension and right ventricle deterioration	3
N-glycosylation signature and its relevance in cardiovascular immunometabolism	3
Neuropeptide Y: Direct vasoconstrictor and facilitatory effects on P2X1 receptor-dependent vasoconstriction in human small abdominal arteries	2
The new role of Tryptophan 2,3- dioxygenase in modulating human endothelial cell and endothelial precursor functions	2
Graphical abstract TOC	2
Graphical abstract TOC	2
Efficacy and safety of tirofiban in patients with acute ischemic stroke treated with endovascular thrombectomy: A frequentist and Bayesian meta-analysis	2
Electrophysiological remodeling in primary versus secondary cardiac hypertrophy: A study in human cardiomyocytes	2
Graphical abstract TOC	2
Inferior vena cava filters: Concept review and summary of current guidelines	2
Percutaneous coronary interventions versus coronary artery bypass graft surgery in coronary artery disease	2
Targeting Cis-regulatory elements for CRISPR-mediated transcriptional activation of the human MIR503HG locus	2
Intracellular Ca2+ dynamics modulation by istaroxime and its metabolite in pulmonary artery smooth muscle cells	2
Trends in colchicine use across the spectrum of coronary artery disease	2
The effect of drugs and stem cell therapies on established abdominal aortic aneurysms in mice: A systematic review and meta-analysis	2
Video analysis of ex-vivo beating hearts during preservation on the TransMedics® organ care system	2
Use of lipid-lowering drugs in restricted health access settings: Results from the Trends in Drug Utilization During COVID-19 Pandemic in Turkey (PANDUTI-TR) study	2
Advances and limitations in angiogenesis assays: Integrating in vitro, in vivo, and emerging technologies	2
Emerging role of mesenchymal cells in cardiac and cerebrovascular diseases: Physiology, pathology, and therapeutic implications	2
Venoactive drugs in the management of chronic venous disease: A critical appraisal of the evidence and comparison with international guidelines	2
Fluorinated perhexiline derivative attenuates vascular proliferation in pulmonary arterial hypertension smooth muscle cells	2
Impact of body size on platelet function in patients with acute coronary syndrome on dual antiplatelet therapy	2
Impaired endothelial function in duchenne muscular dystrophy-associated cardiomyopathy: Insights from hiPSC-derived endothelial cells	2
Pulmonary veno-occlusive disease: Insights from animal models	2
Editorial Board	2
In-vitro studies of the NaV1.5 S805L Brugada mutation: The resting cell voltage is a critical element in determining the pathological or physiological phenotype of the current	2
Comparative effectiveness of oral therapies targeting the prostacyclin pathway in pulmonary arterial hypertension: A systematic review and network meta-analysis	2
Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects	2
Unraveling the pathophysiological role of the PLN-R14del mutation in a novel heterozygous mouse model of dilated cardiomyopathy	2
Single-cell RNA sequencing (scRNA-seq) and its insights into cellular heterogeneity in atherosclerosis	2
Exercise pulmonary hypertension in chronic thromboembolic pulmonary disease without resting pulmonary hypertension: A systematic review and meta-analysis	2
Unvealing organ-specific endothelial heterogeneity and its dysfunction	2
An X-ray computed μ-tomography analysis for the characterization of 3D-heart shape in a model of cardiac plasticity	2
The recent applications of nanotechnology in the diagnosis and treatment of common cardiovascular diseases	1
Ketogenic diet improves chromatin remodeling and rescues mitochondrial dysfunction in ischemic heart disease by regulating PGC-1alpha transcription	1
A slower beat: Aglianico grape pomace extract as a novel modulator of cardiac rhythmicity	1
Effect of high-dose statin therapy on coagulation factors: Lowering of factor XI as a modifier of fibrin clot properties in coronary artery disease	1
Nanocarrier-based drug delivery strategies for Raynaud's phenomenon: Overcoming microvascular and perfusion barriers	1
Quantitative and structural characteristics of mitochondrial DNA in varicose veins	1
A critical appreciation of pathway analysis in atherosclerotic disease. Cellular phenotypic plasticity as an illustrative example	1
The chromogranin A1-373 fragment exerts strong cardioregulatory effects by engaging neuropilin-1 through minimal changes in the protein sequence	1
Protective effects of Salvia Haenkei extract on a model of Doxorubicin-induced cardiotoxicity	1
Intraoperative detection of exosomal proteins associated with cancer risk in older cardiac surgery patients without a history of malignancies	1
Two sides of the same coin: Non-alcoholic fatty liver disease and atherosclerosis	1
Alterations of basal spirometry in long COVID patients. Effects of physical activity	1
Examining the controversies in venous thromboembolism prophylaxis for vascular surgery patients: A critical review	1
NAD+ attenuates cardiac injury after myocardial infarction in diabetic mice through regulating alternative splicing of VEGF in macrophages	1
12-week Dolutegravir treatment marginally reduces energy expenditure but does not increase body weight or alter vascular function in a murine model of Human Immunodeficiency Virus infection	1
PI3KC2α controls cardiac contractility through regulation of β2-adrenergic receptor recycling	1
Organ-specific model of simulated ischemia/reperfusion and hyperglycemia based on engineered heart tissue	1
Novel therapeutic targets for reperfusion injury in ischemic stroke: Understanding the role of mitochondria, excitotoxicity and ferroptosis	1
The use of glycoprotein IIb/IIIa inhibitors in elective PCI – A systematic review and meta-analysis of randomised trials	1
Cellular senescence and senescence-associated secretory phenotype drive multipotent cardiac stem/progenitor cell dysfunction in human diabetic cardiomyopathy independently of age	1
Contents continued	1
Graphical abstract TOC	1
Translational aspects of doxorubicin-induced cardiotoxicity: What we have omitted for the past decades?	1
Reduction of doxorubicine-induced senescence does not provide cardioprotective effect in mice	1
TRPV1 mediates redox-sensitive intracellular Ca2+ release and store-operated Ca2+ entry activation in circulating endothelial colony forming cells	1
A gain of function mutation in PITX2c gene linked to atrial fibrillation alters mitochondrial function and membrane excitability	1
Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes	1
Circulating soluble IL-6 receptor associates with plaque inflammation but not with atherosclerosis severity and cardiovascular risk	1
The pharmacological modulation of PPAR- γ as therapeutic strategy in the failure of arteriovenous fistula	1
Ion channels of the human heart: A comprehensive four-chamber analysis	1
Inhaled argon as a neuroprotective agent after an ischemic event – a fully translational story from animal studies to a human trial	1
Pulmonary pressure recovery in idiopathic, hereditary and drug and toxin-induced pulmonary arterial hypertension: determinants and clinical impact	1
Editorial Board	1
Graphical abstract TOC	1
Telehealth: A winning weapon to face the COVID-19 outbreak for patients with pulmonary arterial hypertension	1
The role of Epsins in atherosclerosis: From molecular mechanisms to therapeutic applications	1
Red light-absorbing conjugated polymer optically modulates Ca2+ dynamics in cardiomyocytes derived from human induced pluripotent stem cells	1
Exploring new cardiovascular frontiers: The Italian cardiovascular research landscape	1
Soluble epoxide hydrolase inhibitor, TPPU, attenuates progression of atherosclerotic lesions and vascular smooth muscle cell phenotypic switching	1