OOIR: Observatory of International Research

Papers

(The TQCC of Vascular Pharmacology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Endothelial dysfunction in acute and long standing COVID−19: A prospective cohort study	67
Extracellular vesicles and cardiovascular system: Biomarkers and Cardioprotective Effectors	66
Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage	64
SARS-CoV-2 spike protein-mediated cell signaling in lung vascular cells	61
Endothelial cells and SARS-CoV-2: An intimate relationship	46
Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection	40
RAAS inhibitors are not associated with mortality in COVID-19 patients: Findings from an observational multicenter study in Italy and a meta-analysis of 19 studies	35
Venous thromboembolism in COVID-19 compared to non-COVID-19 cohorts: A systematic review with meta-analysis	31
Perivascular adipose-derived exosomes reduce macrophage foam cell formation through miR-382-5p and the BMP4-PPARγ-ABCA1/ABCG1 pathways	28
Nectin-4 promotes lymphangiogenesis and lymphatic metastasis in breast cancer by regulating CXCR4-LYVE-1 axis	27
Circular RNA circ_0029589 regulates proliferation, migration, invasion, and apoptosis in ox-LDL-stimulated VSMCs by regulating miR-424-5p/IGF2 axis	23
A possible role for ST2 as prognostic biomarker for COVID-19	21
A new storm on the horizon in COVID-19: Bradykinin-induced vascular complications	20
Anti-inflammatory effects of sodium-glucose co-transporter 2 inhibitors on atherosclerosis	20
Diabetic neuropathy: Molecular approach a treatment opportunity	19
Interleukin-6 level is a powerful predictor of long-term cardiovascular mortality in patients with acute coronary syndrome	19
Factor Xa inhibitor rivaroxaban suppresses experimental abdominal aortic aneurysm progression via attenuating aortic inflammation	18
Extracellular vesicles (EVs) in ischemic conditioning and angiogenesis: Focus on endothelial derived EVs	18
Exercise-induced pulmonary hypertension in HFpEF and HFrEF: Different pathophysiologic mechanism behind similar functional impairment	17
Angiotensin-II activates vascular inflammasome and induces vascular damage	17
Exosomal miR-211 contributes to pulmonary hypertension via attenuating CaMK1/PPAR-γaxis	17
Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction	17
Therapeutic potential of flavonoids in the treatment of chronic venous insufficiency	16
Higher neutrophil-to-lymphocyte ratio (NLR) increases the risk of suboptimal platelet inhibition and major cardiovascular ischemic events among ACS patients receiving dual antiplatelet therapy with ti	16
Effects of statins in primary and secondary prevention for venous thromboembolism events: A meta analysis	15

Simulated hyperglycemia impairs insulin signaling in endothelial cells through a hyperosmolar mechanism	15
Extracellular vesicle-mediated miR135a-5p transfer in hypertensive rat contributes to vascular smooth muscle cell proliferation via targeting FNDC5	14
Circ_0004872 promotes platelet-derived growth factor-BB-induced proliferation, migration and dedifferentiation in HA-VSMCs via miR-513a-5p/TXNIP axis	14
Exploring the regulatory roles of circular RNAs in the pathogenesis of atherosclerosis	14
MCU-dependent mitochondrial calcium uptake-induced mitophagy contributes to apelin-13-stimulated VSMCs proliferation	13
Transplantation of telomerase/myocardin-co-expressing mesenchymal cells in the mouse promotes myocardial revascularization and tissue repair	13
Assessment of ACE1 variants and ACE1/ACE2 expression in COVID-19 patients	13
Loss of Jagged1 in mature endothelial cells causes vascular dysfunction with alterations in smooth muscle phenotypes	13
Sodium-glucose cotransporter type 2 inhibitors prevent ponatinib-induced endothelial senescence and disfunction: A potential rescue strategy	13
Serotonin and chronic hypoxic pulmonary hypertension activate a NADPH oxidase 4 and TRPM2 dependent pathway for pulmonary arterial smooth muscle cell proliferation and migration	13
Increased histone-DNA complexes and endothelial-dependent thrombin generation in severe COVID-19	13
Non-coding RNAs regulate angiogenic processes	12
Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients	12
Tissue optical clearing for 3D visualization of vascular networks: A review	12
Maslinic acid suppresses macrophage foam cells formation: Regulation of monocyte recruitment and macrophage lipids homeostasis	12
Effect of high-dose statin therapy on coagulation factors: Lowering of factor XI as a modifier of fibrin clot properties in coronary artery disease	12
New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis	11
The lncRNA MALAT1 participates in regulating coronary slow flow endothelial dysfunction through the miR-181b-5p–MEF2A–ET-1 axis	11
The short-chain fatty acid butyrate accelerates vascular calcification via regulation of histone deacetylases and NF-κB signaling	11
Inhibition on CXCL5 reduces aortic matrix metalloproteinase 9 expression and protects against acute aortic dissection	11
Risk stratification of patients with SARS-CoV-2 by tissue factor expression in circulating extracellular vesicles	11
4-hydroxy-2-nonenal decreases coronary endothelial cell migration: Potentiation by aldehyde dehydrogenase 2 inhibition	10
Treatment with PCSK9 inhibitors induces a more anti-atherogenic HDL lipid profile in patients at high cardiovascular risk	10
Pravastatin plus L-arginine prevents adverse pregnancy outcomes in women with uteroplacental vascular dysfunction	10
The impact of proangiogenic microRNA modulation on blood flow recovery following hind limb ischemia. A systematic review and meta-analysis of animal studies	10
Tetrandrine promotes angiogenesis via transcriptional regulation of VEGF-A	10
Ischemic heart disease and cardioprotection: Focus on estrogenic hormonal setting and microvascular health	10
High density lipoprotein in atherosclerosis and coronary heart disease: Where do we stand today?	9
CircDIP2C ameliorates oxidized low-density lipoprotein-induced cell dysfunction by binding to miR-556-5p to induce TET2 in human umbilical vein endothelial cells	9
Septic shock as a trigger of arterial stress-induced premature senescence: A new pathway involved in the post sepsis long-term cardiovascular complications	9
Vildagliptin improves vascular smooth muscle relaxation and decreases cellular senescence in the aorta of doxorubicin-treated rats	9
Neuropeptide Y facilitates P2X1 receptor-dependent vasoconstriction via Y1 receptor activation in small mesenteric arteries during sympathetic neurogenic responses	9
Colchicine inhibits the prothrombotic effects of oxLDL in human endothelial cells	9
Arg mediates LPS-induced disruption of the pulmonary endothelial barrier	9
Extrinsic and intrinsic factors influencing metabolic memory in type 2 diabetes	9
Targeting endothelial ion signalling to rescue cerebral blood flow in cerebral disorders	9
Indoxyl sulfate promotes the atherosclerosis through up-regulating the miR-34a expression in endothelial cells and vascular smooth muscle cells in vitro	9
Absence of interaction between rivaroxaban, tacrolimus and everolimus in renal transplant recipients with deep vein thrombosis or atrial fibrillation	8
Hdac9 inhibits medial artery calcification through down-regulation of Osterix	8
Transcriptional regulation of vascular smooth muscle cell proliferation, differentiation and senescence: Novel targets for therapy	8
Chronic cyclooxygenase-2 inhibition prevents the worsening of hypertension and endothelial dysfunction induced by ouabain in resistance arteries of spontaneously hypertensive rats	8
In silico Nigellidine (N. sativa) bind to viral spike/active-sites of ACE1/2, AT1/2 to prevent COVID-19 induced vaso-tumult/vascular-damage/comorbidity	8
Empagliflozin prevents angiotensin II-induced hypertension related micro and macrovascular endothelial cell activation and diastolic dysfunction in rats despite persistent hypertension: Role of endoth	8
Beneficial effects of melatonin on prostanoids pathways in pulmonary hypertensive neonates	8
Osteogenic differentiation and calcification of human aortic smooth muscle cells is induced by the RCN2/STAT3/miR-155-5p feedback loop	8
Optical excitation of organic semiconductors as a highly selective strategy to induce vascular regeneration and tissue repair	8
Perivascular adipose tissue-derived nitric oxide compensates endothelial dysfunction in aged pre-atherosclerotic apolipoprotein E-deficient rats	8
The lncRNA PAHRF functions as a competing endogenous RNA to regulate MST1 expression by sponging miR-23a-3p in pulmonary arterial hypertension	8
Intensive low-density lipoprotein cholesterol lowering improves fibrin clot properties: Association with lipoproteins and C-reactive protein	8
Sitagliptin, a dipeptidyl peptidase-4 inhibitor, attenuates apoptosis of vascular smooth muscle cells and reduces atherosclerosis in diabetic apolipoprotein E–deficient mice	8

Effects of rivaroxaban and dabigatran on local expression of coagulation and inflammatory factors within human aortic stenotic valves	8
Optimal duration and combination of antiplatelet therapies following percutaneous coronary intervention: a meta-analysis	7
The potential role of thymoquinone in preventing the cardiovascular complications of COVID-19	7
Targeting androgen receptor in macrophages inhibits phosphate-induced vascular smooth muscle cell calcification by decreasing IL-6 expression	7
Challenges facing the clinical translation of cardioprotection: 35 years after the discovery of ischemic preconditioning	7
Crosstalk of TLR4, vascular NADPH oxidase, and COVID-19 in diabetes: What are the potential implications?	7
Vitamin D deficiency is associated with impaired reperfusion in STEMI patients undergoing primary percutaneous coronary intervention	7
Ozagrel a thromboxane A2 synthase inhibitor extenuates endothelial dysfunction, oxidative stress and neuroinflammation in rat model of bilateral common carotid artery occlusion induced vascular dement	7
Benefits with drug-coated balloon as compared to a conventional revascularization strategy for the treatment of coronary and non-coronary arterial disease: a comprehensive meta-analysis of 45 randomiz	7
Increased fractalkine and vascular dysfunction in obesity and in type 2 diabetes. Effects of oral antidiabetic treatment	7
Stimulation of angiotensin II receptor 2 preserves cognitive function and is associated with an enhanced cerebral vascular density after stroke	7
Thromboprophylaxis strategies to improve the prognosis of COVID-19	7
Exploring the mechanisms of action of gliflozines in heart failure and possible implications in pulmonary hypertension	6
Soluble epoxide hydrolase inhibitor, TPPU, attenuates progression of atherosclerotic lesions and vascular smooth muscle cell phenotypic switching	6
The effect of the 2019 ESC/EAS dyslipidaemia guidelines on low-density lipoprotein cholesterol goal achievement in patients with acute coronary syndromes: The ACS EuroPath IV project	6
Apoptosis signal-regulating kinase-1 regulates thrombin-induced endothelial permeability	6
MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca2+ channels and PIP2	6
Angiocrine endothelium: From physiology to atherosclerosis and cardiac repair	6
Residual platelet reactivity in low-dose aspirin-treated patients with class 1 obesity	6
Inducible degrader of LDLR: A potential novel therapeutic target and emerging treatment for hyperlipidemia	6
Effect of enoxaparin on plasma fibrin clot properties and fibrin structure in patients with acute pulmonary embolism	5
COMP-Ang1: Therapeutic potential of an engineered Angiopoietin-1 variant	5
Brain-derived neurotrophic factor is a full endothelium-derived factor in rats	5
The close link between brain vascular pathological conditions and neurodegenerative diseases: Focus on some examples and potential treatments	5
Aging, sex and NLRP3 inflammasome in cardiac ischaemic disease	5
Late phase endothelial cell inflammation is characterized by interferon response genes and driven by JAK/STAT, not NFκB	5
Long-term dietary n3 fatty acid prevents aging-related cardiac diastolic and vascular dysfunction	5
Β-blockers activate autophagy on infantile hemangioma-derived endothelial cells in vitro	5
Influence of long-term proteasome inhibition on platelet responsiveness mediated by bortezomib	5
Endothelial TrkB receptor activation controls vascular tone of rat middle cerebral artery	4
Exercise-induced pulmonary hypertension in HIV patients: Association with poor clinical and immunological status	4
The effect of dihydroceramide desaturase 1 inhibition on endothelial impairment induced by indoxyl sulfate	4
Ticagrelor as compared to conventional antiplatelet agents in coronary artery disease: A comprehensive meta-analysis of 15 randomized trials	4
G6PD is a critical enabler of hypoxia-induced accumulation of macrophages and platelets in mice lungs and contributor to lung inflammation	4
Melatonin treatment during chronic hypoxic gestation improves neonatal cerebrovascular function	4
Immune responses against oxidized LDL as possible targets for prevention of atherosclerosis in systemic lupus erythematosus	4
TLR4-Myd88 pathway upregulated caveolin-1 expression contributes to coronary artery spasm	4
Pulmonary pressure recovery in idiopathic, hereditary and drug and toxin-induced pulmonary arterial hypertension: determinants and clinical impact	4
Platelet apelin receptor expression is reduced in patients with acute myocardial infarction	4
Increased Ephrin-B2 expression in pericytes contributes to retinal vascular death in rodents	4
Targeting residual inflammatory risk: The next frontier for atherosclerosis treatment and prevention	4
Berberine inhibits osteogenic differentiation of aortic valve interstitial cells by interfering Smad1/5/8 and NF-κB pathways	4
Kidney endothelial cell heterogeneity, angiocrine activity and paracrine regulatory mechanisms	4
SGLT2-i prevent left ventricular dysfunction induced by anthracycline in mouse model: A systematic-review and meta-analysis	4
Hinokitiol produces vasodilation in aortae from normal and angiotensin II- induced hypertensive rats via endothelial-dependent and independent pathways	4
Comparative bioavailability of inhaled treprostinil administered as LIQ861 and Tyvaso® in healthy subjects	4
A review of genetically-driven rodent models of pulmonary hypertension	4
Insulin-treated versus noninsulin-treated diabetes and risk of ischemic stroke in patients with atrial fibrillation	4
Mast cells participate in smooth muscle cell reprogramming and atherosclerotic plaque calcification	4