OOIR: Observatory of International Research

Papers

(The TQCC of Cell Cycle is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
RNF220 enhances USP22 to promote cell growth, metastasis and stemness in hepatocellular carcinoma by activating the Akt pathway	102
Understanding cellular senescence: pathways involved, therapeutics and longevity aiding	92
Thyroid hormone enhances estrogen-mediated proliferation and cell cycle regulatory pathways in steroid receptor-positive breast Cancer	48
Statement of Retraction: Role of p75 neurotrophin receptor in neuronal autophagy in intracerebral hemorrhage in rats through the mTOR signaling pathway	42
Statement of Retraction: p38/p53/miR-200a-3p feedback loop promotes oxidative stress-mediated liver cell death	41
Statement of Retraction: LncRNA CYTOR drives L-OHP resistance and facilitates the epithelial–mesenchymal transition of colon carcinoma cells via modulating miR-378a-5p/SERPINE1	36
High expression of COL6A1 predicts poor prognosis and response to immunotherapy in bladder cancer	35
Statement of Retraction: The circular RNA ZNF292 alleviates OGD-induced injury in H9c2 cells via targeting BNIP3	35
DNMT1-mediated epigenetic suppression of FBXO32 expression promoting cyclin dependent kinase 9 (CDK9) survival and esophageal cancer cell growth	34
A nonsteroidal anti-inflammatory drug, zaltoprofen, inhibits the growth of extraskeletal chondrosarcoma cells by inducing PPARγ, p21, p27, and p53	34
Fasting inhibits glycolysis and migration/invasion in gallbladder cancer via PCBP2/ANGPTL4 signaling	33
Zinc promotes cell proliferation via regulating metal-regulatory transcription factor 1 expression and transcriptional activity in pulmonary arterial hypertension	32
microRNA-206 prevents hepatocellular carcinoma growth and metastasis via down-regulating CREB5 and inhibiting the PI3K/AKT signaling pathway	28
circFCHO2 promotes gastric cancer progression by activating the JAK1/STAT3 pathway via sponging miR-194-5p	27
Integrated analysis of FHIT gene alterations in cancer	27
CDK4/6 inhibition confers protection of normal gut epithelia against gemcitabine and the active metabolite of irinotecan	27
LINC02535/miR-30a-5p/GALNT3 axis contributes to lung adenocarcinoma progression via the NF- κ B signaling pathway	27
SQSTM1 facilitates oocyte maturation through inducing ACLY degradation mediated by selective autophagy	26
LncRNA FGF7-5 and lncRNA GLRX3 together inhibits the formation of carotid plaque via regulating the miR-2681-5p/ERCC4 axis in atherosclerosis	24
Depleting ANTXR1 suppresses glioma growth via deactivating PI3K/AKT pathway	24
Influence of bacterial proteins on the host’s cell cycle	24
Impact of NOTCH1 polymorphisms on liver cancer in a Chinese Han population	23
Discovery of common molecular signatures and drug repurposing for COVID-19/Asthma comorbidity: ACE2 and multi-partite networks	22
Rewiring the mTOR, CDH1, APC/C, PFKFB3 axis: a glycolytic pulse to ignite the G0/G1 gateway	21
Exploring the multifaceted role of RASGRP1 in disease: immune, neural, metabolic, and oncogenic perspectives	21

Dehydroandrographolide alleviates rheumatoid arthritis by inhibiting neutrophil activation via LMIR3 in collagen induced arthritis rats	20
LncRNA FAM83A-AS1 promotes epithelial–mesenchymal transition of pancreatic cancer cells via Hippo pathway	19
The role of ferroptosis in endothelial cell dysfunction	19
Downregulation of cancer-associated fibroblast exosome-derived miR-29b-1-5p restrains vasculogenic mimicry and apoptosis while accelerating migration and invasion of gastric cancer cells via immunoglo	19
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification	19
USP38 inhibits colorectal cancer cell proliferation and migration via downregulating HMX3 ubiquitylation	18
The dual role of circular RNAs in paclitaxel resistance: insights into molecular mechanisms and clinical implications	18
SRF inhibitors reduce prostate cancer cell proliferation through cell cycle arrest in an isogenic model of castrate-resistant prostate cancer	16
Astragaloside IV attenuate MI-induced myocardial fibrosis and cardiac remodeling by inhibiting ROS/caspase-1/GSDMD signaling pathway	16
Statement of Retraction: Long non-coding RNA CCAT1 promotes multiple myeloma progression by acting as a molecular sponge of miR-181a-5p to modulate HOXA1 expression	16
Astrocyte-derived stanniocalcin-1 orchestrates epileptogenesis through NF-κB-dependent neuroinflammation	16
Glutamine regulates the cellular proliferation and cell cycle progression by modulating the mTOR mediated protein levels of β-TrCP	16
Statement of Retraction: miR-15b-3p promotes the malignant progression of endometrial cancer cells through targeting KLF2	16
Methylation of lncSHGL promotes adipocyte differentiation by regulating miR-149/Mospd3 axis	16
The involvement of cyclin-dependent kinase 7 (CDK7) and 9 (CDK9) in coordinating transcription and cell cycle checkpoint regulation	16
Linc00883 affects colorectal cancer through miR-577/FKBP14 axis: a novel mechanism for regulating colorectal cancer cell proliferation, invasion, and migration	16
YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes	16
Exosomes in hepatocellular carcinoma: involvement in reprogramming the tumor microenvironment for immune evasion, metastasis, angiogenesis, and drug resistance	15
Statement of Retraction: Silencing of EPCAM suppresses hepatic fibrosis and hepatic stellate cell proliferation in mice with alcoholic hepatitis via the PI3K/Akt/mTOR signaling pathway	15
Statement of Retraction: A novel role for fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells	15
Surfeit locus protein 4 modulates endoplasmic reticulum function and maintains oocyte quality	15
Repression of linc01555 up-regulates angiomotin-p130 via the microRNA-122-5p/clic1 axis to impact vasculogenic mimicry-mediated chemotherapy resistance in small cell lung cancer	15
Mitotic error correction and the spindle assembly checkpoint: a tension-filled relationship	15
Identification and validation of key miRNAs and a microRNA-mRNA regulatory network associated with liver cancer	15
CircRnas in atherosclerosis, with special emphasis on the spongy effect of circRnas on miRnas	15
Statement of Retraction: Overexpression of HIF-1α protects PC12 cells against OGD/R-evoked injury by reducing miR-134 expression	15
Upregulated miR-322-5p regulates cell cycle and promotes cell proliferation and apoptosis by directly targeting Wee1 in mice liver injury	15
RING finger gene 180 inhibits osteosarcoma progression through regulating chromobox homolog 4 ubiquitination	14
Goosecoid facilitates the metastasis of pancreatic adenocarcinoma by enhancing EMT and stemness via regulating TGF-β/SMAD2/3 signaling	14
Pumilio RNA binding family member 1 deficiency activates anti-tumor immunity in hepatocellular carcinoma via restraining M2 macrophage polarization	14
CircRNA OXCT1 promotes the malignant progression and glutamine metabolism of non-small cell lung cancer by absorbing miR-516b-5p and upregulating SLC1A5	14
LncRNA MINCR attenuates osteoarthritis progression via sponging miR-146a-5p to promote BMPR2 expression	14
NSUN2-mediated m5C modification of PGK1 mRNA promotes cell growth, invasion, stemness and glycolysis in gastric cancer	13
RNF6 promotes gastric cancer progression by regulating CCNA1/CREBBP transcription	13
HRD1 functions as a tumor suppressor in ovarian cancer by facilitating ubiquitination-dependent SLC7A11 degradation	13
Statement of Retraction: Down-regulated microRNA-141 facilitates osteoblast activity and inhibits osteoclast activity to ameliorate osteonecrosis of the femoral head via up-regulating TGF-β2	13
Expression of the cytokinesis regulator PRC1 results in p53-pathway activation in A549 cells but does not directly regulate gene expression in the nucleus	13
Statement of Retraction: LncRNA CCAT1 modulates the sensitivity of paclitaxel in nasopharynx cancers cells via miR-181a/CPEB2 axis	13
Statement of Retraction: Long noncoding RNA LINC00520 accelerates progression of papillary thyroid carcinoma by serving as a competing endogenous RNA of microRNA-577 to increase Sphk2 expression	13
Statement of Retraction: Long non-coding RNA PCAT1 drives clear cell renal cell carcinoma by upregulating YAP via sponging miR-656 and miR-539	13
Isoalantolactone mediates the degradation of BCR-ABL protein in imatinib-resistant CML cells by down-regulating survivin	13
Beta-carotene regulates the biological activity of EGF in IEC6 cells by alleviating the inflammatory process	12
DLEU2 modulates proliferation, migration and invasion of platelet-derived growth factor-BB (PDGF-BB)-induced vascular smooth muscle cells (VSMCs) via miR-212-5p/YWHAZ axis	12
Autophagy unrelated transcriptional mechanisms of hydroxychloroquine resistance revealed by integrated multi-omics of evolved cancer cells	12
Knockout of cyclin B1 in granulosa cells causes female subfertility	12
Epididymal segment-specific miRNA and mRNA regulatory network at the single cell level	12
Exosomes derived from mesenchymal stem cells ameliorate impaired glucose metabolism in myocardial Ischemia/reperfusion injury through miR-132-3p/PTEN/AKT pathway	12
CKS2 promotes the malignant phenotypes of bladder cancer cells via PI3K/AKT signaling pathway activation	12
Unfolded protein response complexity in gynecological tumor dynamics: therapeutic challenges and future perspectives	12
Correction	12

An innovative systematic approach introduced the involved lncRNA-miR-mRNA network in cell cycle and proliferation after conventional treatments in breast cancer patients	12
Statement of Retraction: Fascin1 mediated release of pro-inflammatory cytokines and invasion/migration in rheumatoid arthritis via the STAT3 pathway	11
Expression of Concern: Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing	11
Exosomes derived from AHR-overexpressing human umbilical cord mesenchymal stem cells attenuate H/R injury via AHR/NLRP3 pathway	11
Association between MIR31HG polymorphisms and the risk of Lumbar disc herniation in Chinese Han population	11
Nup50 plays more than one instrument	11
Circ_0001955 promotes the progression of non-small cell lung cancer via miR-769-5p/EGFR axis	11
The mystery of phospho-Drp1 with four adaptors in cell cycle: when mitochondrial fission couples to cell fate decisions	11
Statement of Retraction: Long non-coding RNA GAS5 sensitizes renal cell carcinoma to sorafenib via miR-21/SOX5 pathway	11
The interplay between autophagy, p16 ^INK4a , and senescence in tumor cells: a systematic review	11
HDAC6 decreases H4K16 and α-tubulin acetylation during porcine oocyte maturation	11
HGH1 and the immune landscape: a novel prognostic marker for immune-desert tumor microenvironment identification and immunotherapy outcome prediction in human cancers	11
Statement of Retraction: Hsa_circ_0008360 sponges miR-186-5p to target CCND2 to modulate high glucose-induced vascular endothelial dysfunction	11
Locus-specific transcriptional regulation of transposable elements by p53	11
Systematic analysis of the oncogenic role of FAM83D across cancers based on data mining	11
The role of FOXO1-mediated autophagy in the regulation of bone formation	11
Pan-cancer landscape of basement membrane: multi-omics research and single-cell sequencing validation	11
Statement of Retraction: MicroRNA-203 restrains epithelial–mesenchymal transition, invasion and migration of papillary thyroid cancer by downregulating AKT3	10
Knockdown of hCINAP sensitizes colorectal cancer cells to ionizing radiation	10
Statement of Retraction: MicroRNA-422a functions as a tumor suppressor in non-small cell lung cancer through SULF2-mediated TGF-β/SMAD signaling pathway	10
The SGLT2 inhibitor canagliflozin attenuates mitochondrial oxidative stress and alterations of calcium handling induced by high glucose in human cardiac fibroblasts	10
Functions of exosomal microRNAs from adipose tissue in diabetes mellitus and related cardiovascular pathologies	10
Expression of Concern: Down-regulated microRNA-183 mediates the Jak/Stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting Foxp1	10
Circ_0057452 sponges miR-7-5p to promote keloid progression through upregulating GAB1	10
Statement of Retraction: Litchi Seed Aqueous Extracts play a role in suppression of epithelial-mesenchymal transition, invasion and migration in breast cancer cells	10
Succinate reduces biological activity and mitochondrial function of human adipose-derived stem cells	10
Impact of sunitinib resistance on clear cell renal cell carcinoma therapeutic sensitivity in vitro	10
Statement of Retraction: Upregulation of microRNA-576-5p protects from steroid-induced avascular necrosis of the femoral head by suppressing ANXA2	10
Upregulation of miR-151-5p promotes the apoptosis of intestinal epithelial cells by targeting brain-derived neurotrophic factor in ulcerative colitis mice	10
Statement of Retraction: MicroRNA-129-5p affects immune privilege and apoptosis of nucleus pulposus cells via regulating FADD in intervertebral disc degeneration	10
Bit1 is involved in regulation between integrin and TGFβ signaling in lens epithelial cells	10
Statement of Retraction: CircLNPEP promotes the progression of ovarian cancer through regulating miR-876-3p/ WNT5A axis	10
Oct4 promoted proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) in colon cancer cells by activating the SCF/c-Kit signaling pathway	9
Genetic variants underlying spermatogenic arrests in men with non-obstructive azoospermia	9
LncRNA FAM138B inhibits the progression of non-small cell lung cancer through miR-105-5p	9
CST/Polα/primase-mediated fill-in synthesis at DSBs	9
NPCs and APBs: two HUBs of non-canonical homology-based recombination at telomeres?	9
Substance P promotes the progression of bronchial asthma through activating the PI3K/AKT/NF-κB pathway mediated cellular inflammation and pyroptotic cell death in bronchial epithelial cells	9
Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration	9
Deficiency of lipopolysaccharide binding protein facilitates adipose browning, glucose uptake and oxygen consumption in mouse embryonic fibroblasts via activating PI3K/Akt/mTOR pathway and inhibiting	9
In vitro modulation of adipocyte differentiation by tenofovir alafenamide/disoproxil fumarate following challenge with recent ARV drugs	9
SAMHD1, positively regulated by KLF4, suppresses the proliferation of gastric cancer cells through MAPK p38 signaling pathway	9
Regulation of microtubule growth rates and their impact on chromosomal instability	9
Migrasomes: the “functional footprints” left by cell migration	9
Construction and validation of predictive model based on endoplasmic reticulum stress-related genes for triple-negative breast cancer	9
Unfolded protein response in endothelial injury	9
Hsa_circ_0014784-induced YAP1 promoted the progression of pancreatic cancer by sponging miR-214-3p	9
β-Klotho inhibits CSF-1 secretion and delays the development of endometrial cancer	9
Effects and mechanisms of trifluridine alone or in combination with cryptotanshinone in inhibiting malignant biological behavior of gastric cancer	9