OOIR: Observatory of International Research

Papers

(The median citation count of Lymphatic Research and Biology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Analysis of Different Lymphedema Assessment Tools in Women with Breast Cancer After Mastectomy	49
Lipedema: Focus on Disease Magnitude and Quality-of-Life	32
Automated Measurement of Skin Thickness in Computed Tomography Images for Unilateral Lower Extremity Lymphedema	30
Research Matters	28
The ICC Compression Questionnaire: A Comprehensive Tool to Evaluate Compression Materials or Devices Applied in Subjects with Lymphedema or Chronic Venous Disease	25
Intermittent Pneumatic Compression for the Treatment of Lower Limb Lymphedema: A Pilot Trial of Sequencing to Mimic Manual Lymphatic Drainage Versus Traditional Graduated Sequential Compression	21
Effects of Aerobic Exercise with Manual Lymphatic Drainage in Chronic Venous Insufficiency Patients	20
Usefulness of 33 MHz Linear Probe in Lymphatic Ultrasound for Lymphedema Patients	19
Clinical Evaluation of a Novel Wearable Compression Technology in the Treatment of Lymphedema, an Open-Label Controlled Study	19
Development and Evaluation of a Satisfaction Questionnaire About Therapeutic Textile Devices Used for Breast Cancer-Related Lymphedema	15
Therapeutic Potential of the Prolyl Hydroxylase Inhibitor Roxadustat in a Mouse Hindlimb Lymphedema Model	14
Sirolimus for Venous Malformations: A Systematic Review of Efficacy and Safety	13
Effectiveness of Mobiderm Autofit in the Intensive Phase of Breast Cancer-Related Lymphedema Treatment: A Case Series	13
Management of Complex Lymphatic Anomalies with Severe Bony Involvement	13
Fluid Distribution: Response to Intermittent Pneumatic Compression in People With and Without Primary Lymphedema	12
Recent Advances in Therapeutic Modalities Against Breast Cancer-Related Lymphedema: Future Epigenetic Landscape	12
Acute Effects of Manual Lymphatic Drainage and Compression with Exercise Therapy on Breast Lymphedema Following Breast-Conserving Surgery and Radiotherapy	11
Clinical Significance of Serum Collagen Type IV and Procollagen Type III N-Peptide Levels in Diagnosis and Differential Diagnosis of Lymphedema	11
Hardness Sensed by Skin Palpation in Legs with Lymphedema Is Predominantly Correlated with Dermal Thickening	11
Changes in the Diameter of Lymphatic Vessels and Veins Due to Body Position, Evaluated by Ultrasound	10
Children and Young People with Lymphedema: The Education Need of Health Care Professionals	9
Lymphoedema: Taking Control by John Boyages (BC Publishing, Sydney, 2025)	9
Clinical Utility of Bioimpedance Analysis for Upper Limb Lymphedema with Surgical Treatment	9
Circumferential Measurements to Calculate Lower Limb Volume in Persons with Lymphedema: What Segment Length Is to Be Recommended?	9
Microgravity and Lymphatics: Why Space Programs Need Lymphedema Physiology Specialists	9

Effects of Forearm Bandaging Technique, Muscle Contraction, and Additional Compression Pad Use on Sub-Bandage Pressure	8
What Should We Focus on When Managing Breast Cancer-Related Lymphedema to Improve Quality of Life?	8
Usefulness of Tapered Cutting Needles for Lymphaticovenular Anastomosis	8
Extending Diagnostic Imaging Accuracy in Lymphedema	8
Evidence-Based Practice Guideline for the Management of Lymphedema Proposed by the Japanese Lymphedema Society	8
Acknowledgment of Reviewers 2023	8
Development of Pressure Sensors to Help Support Community Lymphedema Monitoring: A Scoping Review	8
Long-Term Effectiveness of Combined Intermittent Pneumatic Compression Plus Low-Level Laser Therapy in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial	8
Hypoxia Impairs Migration of Human Dermal Lymph Endothelial Cells: Implications for Lymphedema Pathogenesis	8
Validity Testing of the Head and Neck Lymphedema and Fibrosis Symptom Inventory	7
Static and Dynamic Imbalance in Patients with Breast Cancer-Related Lymphedema	7
Measurement Properties of the Lymphedema Life Impact Scale	7
Predictors of Quality of Life in Patients with Breast Cancer-Related Lymphedema: Effect of Age, Lymphedema Severity, and Anxiety	7
Acknowledgment of Reviewers 2022	7
The Role of Lymphangiogenesis in Coronary Atherosclerosis	7
Research Matters	7
Modeling of Lymphedema Distribution and Complex Decongestive Therapy Effectiveness	7
Psychometric Evaluation of the Bahasa Malaysia Version of the Lymphedema Functioning, Disability, and Health Questionnaire for Upper Limb Lymphedema in Patients with Breast Cancer-Related Lymphedema	7
Efficacy of Therapeutic Ultrasound Added to Complex Decongestive Therapy in Breast Cancer-Related Lymphedema	6
Comparison of Actual and Predicted Resting Metabolic Rate in Women with Lipedema	6
Safety Evaluation of a Device for Treatment of Lymphedema of the Upper Extremity	6
Can Lymphatic Transport Impaired by Total Knee Arthroplasty be Managed with Manual Lymphatic Drainage?	6
Assessment of Arm Volume Using a Tape Measure Versus a 3D Optical Scanner in Survivors with Breast Cancer-Related Lymphedema	6
Re: “Establishing Standards for Centers of Excellence for the Diagnosis and Treatment of Lymphatic Disease” by Chang et al.	6
Tissue Dielectric Constant Combined With Arm Volume Measurement as Complementary Methods in Detection and Assessment of Breast Cancer-Related Lymphedema	6
Acknowledgment of Reviewers 2021	6
Estimates for Assessment of Lymphedema: Reliability and Validity of Extremity Measurements	6
Research Matters	6
How Can Adjustable Velcro Wraps Help in the Management of Lymphedema in the Absence of Complex Physical Therapy Facilities	6
A Pilot Study of Determining the Reliability of a New Three-Dimensional Scanning System for Measuring Truncal Thickness After Breast Cancer Surgery	6
Update February 2024	6
Abnormal Pulmonary Lymphatic Flow on Novel Lymphangiographic Imaging Supports a Common Etiology of Lymphatic Plastic Bronchitis and Nontraumatic Chylothorax	6
Research Matters	5
Response to Letter: Keith et al., Proposed Framework for Research Case Definitions of Lipedema, 22, 2: 93-105	5
The Prospective Natural History Study of Patients with Intractable Venous Malformation and Klippel–Trenaunay Syndrome to Guide Designing a Proof-of-Concept Clinical Trial for Novel Therapeutic Interve	5
Seasonal Variation in Upper Limb Size, Volume, Fluid Distribution, and Lymphedema Diagnosis, Following Breast Cancer Treatment	5
Update February 2023	5
The Impact of Dietary Fat in Lymphatic Anomalies	5
Early Detection of Breast Cancer-Related Lymphedema: Accuracy of Indocyanine Green Lymphography Compared with Bioimpedance Spectroscopy and Subclinical Lymphedema Symptoms	5
Lymphedema After Axillary Lymph Node Dissection in Breast Cancer: Prevalence and Risk Factors—A Single-Center Retrospective Study	5
Research Matters	5
Reliability of Jeweler Rings and a Revised Figure-of-Eight Circumference Protocol for the Assessment of Finger and Hand Circumferences	5
Safety and Efficacy of a Mobiderm Compression Bandage During Intensive Phase of Decongestive Therapy in Patients with Breast Cancer-Related Lymphedema: A Randomized Controlled Trial	5
Factors Predicting the Effect of a Complex Decongestive Therapy in Patients with Mild Lymphedema Following Mastectomy for Early Stage Breast Cancer	5
The Prevalence of the Axillo-Inguinal Lymphatic Pathway in Lymphedema of the Extremities and Potential Therapeutic Implications	5
Measuring Lymph Flow Velocity in Lymphatic Collecting Vessels Using a Transit Time Ultrasound Flowprobe	5
Assessment of Edematous Changes Using Three-Dimensional Body Scanning and Segmental–Bioelectrical Impedance Spectroscopy	5
Update August 2023	4
Update April 2022	4
Agreement Between Optoelectronic Volumetry and Circumferential Girth Measurements to Diagnose Lymphedema in Patients Submitted to Axillary Radical Lymphadenectomy for Treatment of Cutaneous Melanoma	4

Sampling Thoracic Duct Lymph After Esophagectomy: A Pilot Study Investigating the “Gut-Lymph” Concept	4
Characteristic Single Photon Emission Computed Tomography-Computed Tomography Findings in Lower Extremity Lymphedema: Comparison to Indocyanine Green Lymphography	4
Adding Pneumatic Compression Therapy in Lower Extremity Lymphedema Increases Compliance of Treatment, While Decreasing the Infection Rate	4
A Comparison of Bioimpedance Spectroscopy or Tape Measure Triggered Compression Intervention in Chronic Breast Cancer Lymphedema Prevention	4
Prevalence and Prognostic Role of Lymphedema in Patients with Deep Venous Thrombosis and Thrombophlebitis	4
Relation Between Characteristics of Indocyanine Green Lymphography and Development of Breast Cancer-Related Lymphedema	4
Validation of the Lymphedema Quality of Life Questionnaire for German Patients with Lipedema	4
CDH5, a Possible New Candidate Gene for Genetic Testing of Lymphedema	4
Diagnosis of Lymphedema and Subjective Symptoms in the Lower Abdomen and Genital Region	4
Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for Lymphatic Research and Biology	3
Research Matters	3
Improvement of Limb Volumes After Bariatric Surgery in Nine End-Stage Primary, Secondary, and Obesity-Induced Lymphedema Patients: A Multiple Case Report	3
Chylous Reflux in Pediatric Primary Lymphedema of the Lower Limbs and Genitalia: A Retrospective Study of 167 Patients	3
Update June 2022	3
The Comparative Frequency of Breast Cancer-Related Lymphedema Determined by Perometer and Circumferential Measurements: Relationship with Functional Status and Quality of Life	3
Lymphatic Drainage of the Abdominal Wall Within the Extended Nodal Dissection Template During Prostate Cancer Surgery-Mapping Overlapping Patterns	3
Usefulness of Ultrasound Assessment of Breast Cancer–Related Lymphedema	3
Evaluating the Surgical Outcome of Lymphovenous Anastomosis in Breast Cancer-Related Lymphedema Using Tc-99m Phytate Lymphoscintigraphy: Preliminary Results	3
Visualization of Both the Superficial and Deep Lymphatic System of the Upper Extremity Using Magnetic Resonance Lymphography	3
Disease Burden Estimation of Lymphatic Filariasis in an Endemic Area	3
The Effect of Manual Lymph Drainage and Compression Bandaging for Stage 2 Breast Cancer-Related Lymphedema: A Randomized Controlled Trial	3
Acupuncture Treatment for Breast Cancer-Related Lymphedema: A Randomized Pilot Study	3
Physical Therapy in Women with Early Stage Lipedema: Potential Impact of Multimodal Manual Therapy, Compression, Exercise, and Education Interventions	3
Research Matters	3
Quantification of Lymphangiogenesis in the Murine Lymphedema Tail Model Using Intravital Microscopy	3
A Family-Based Study of Inherited Genetic Risk in Lipedema	3
A New Secondary Chronic Lymphedema Rat Model Improved by High-Fat Diet	3
Early Investigation of the Gut–Lymph Concept	3
Super-Microsurgery for Vessels with Diameters Smaller Than 0.5 mm	3
Effect of Physical Therapy on Circumference Measurement and Extremity Volume in Patients Suffering from Lipedema with Secondary Lymphedema	3
Causal Association Between Childhood Body Mass Index and Phlebitis and Thrombophlebitis: An Analysis Using Mendelian Randomization	3
Reliability and Validity of the Korean Version of the Lymphedema Quality of Life Questionnaire in Breast Cancer-Related Lymphedema Patients	3
Evaluation of Chylothorax Using Dynamic Contrast-Enhanced Magnetic Resonance Lymphangiography After Lung Cancer Surgery	3
Prediction of the Presence of Fluid Accumulation in the Subcutaneous Tissue in BCRL Using Texture Analysis of Ultrasound Images	3
Tissue Dielectric Constant and Water Displacement Method Can Detect Changes of Mild Breast Cancer-Related Arm Lymphedema	3
Cross-Cultural Adaptation and Preliminary Validation of Upper Limb Lymphedema Quality of Life Questionnaire (ULL-27) in Italian Female Patients with Breast Cancer-Related Lymphedema	3
Lower Limb Lipedema–Superficial Lymph Flow, Skin Water Concentration, Skin and Subcutaneous Tissue Elasticity	2
Research Matters	2
A Low-Cost, Portable, and Mobile-Based Bioimpedance Lymphedema Diagnosis and Monitoring System (Mobilymph): A Validation Study	2
Psychological Changes During Inpatient Conservative Treatment for Lymphedema	2
The Interrater Reliability of the Scoring of the Lymphatic Architecture and Transport Through Near-InfraRed Fluorescence Lymphatic Imaging in Patients with Breast Cancer-Related Lymphedema	2
Assessment Tools to Quantify the Physical Aspects of Lipedema: A Systematic Review	2
High Pressure 3 × 30 Minute Compression Methods for Advanced Lower Limb Lymphedema Patients	2
The Relationship Between Sleep Quality, Fatigue, and Quality of Life in Women with Lipedema	2
A Comparison of Supine Versus Stand-on Bioimpedance Devices to Assess Breast Cancer-Related Lymphedema	2
Lymphatic Malformations: What Can We Learn from the Fluid	2
Research Matter	2
Lower Extremity Lymphedema: The Effect upon Gait and Function	2
Early Detection of Breast Cancer-Related Lymphedema in COVID-19 Pandemic	2
Weight Gain and Lymphedema After Breast Cancer Treatment: Avoiding the Catch-22?	2
Does Fear of Movement Affect Fatigue and Quality of Life in Lower Extremity Lymphedema?	2
Efficacy of Lymphaticovenular Anastomosis for Secondary Upper Extremity Lymphedema: Treatment Strategies with Effects of Compression Therapy Discontinuation and Site-Specific Evaluation of the Upper E	2
Pressure Curves, Static and Dynamic Stiffness of Different Two-Component Compression Systems for the Treatment of Chronic Edema of the Lower Limbs	2
Lymphedema After Sentinel Lymph Node Biopsy: Who Is at Risk?	2
Sirolimus in the Treatment of Microcystic Lymphatic Malformations: A Systematic Review	2
Research Matters	2
Complex Lymphatic Anomalies: Report on a Patient Registry Using the Latest Diagnostic Guidelines	2
The Concept of Palliative Lymphaticovenular Anastomosis	2
Preoperative Mapping of Lymphatic Vessels by Multispectral Optoacoustic Tomography	2
A Method to Improve the Accuracy for the Comparison of Consecutively Determined Upper Limb Cross-Sectional Area Profiles of Test Subjects: Impact on (Segmental) Limb Volume and Local Limb Circumferenc	2
Investigation of the Less Known Effects of Manual Lymphatic Drainage: A Narrative Review	2
Evaluation of the Treatment Process with Home Exercise Program and Telerehabilitation in Patients with Breast Cancer-Related Lymphedema: A Case-Control Study	2
Body Fluid Trend and Prevalence of Lymphedema After Gynecological Cancer Surgery	2
Intracellular and Extracellular Water Balance in Patients with Lipedema	1
Lymphedema, Fatigue, and Quality of Life in Breast Cancer Survivors with Axillary Lymph Node Dissection	1
Lymphoscintigraphic Investigations for Axillary Web Syndromes	1
Research Matters	1
Cytological and Biochemical Analyses of Lymphatic Fluid from Patients with Lymphatic Malformations	1
Re: “Limb Volume Changes and Activities of Daily Living: A Prospective Study” by Park et al.	1
Analysis of the Risk Factors of Breast Cancer-Related Lymphedema and Construction and Evaluation of a Prediction Model	1
Far Infrared Radiation Therapy for Gynecological Cancer-Related Lymphedema Is an Effective and Oncologically Safe Treatment: A Randomized-Controlled Trial	1
Adipose Tissue in Lymphedema: A Central Feature of Pathology and Target for Pharmacologic Therapy	1
Update December 2021	1
Investigation of the Association Between Breast Cancer-Related Lymphedema and the Side Effects of Taxane-Based Chemotherapy Using Indocyanine Green Lymphography	1
Combined Lymphovenous Anastomosis and Great Saphenous Vein Stripping for Comorbid Lymphedema and Varicose Veins	1
Letter: Tips for Treatment and Following Secondary Upper Extremity Lymphedema	1
Research Matters	1
Successful Sclerotherapy for Cervicofacial Macrocystic Lymphatic Malformations Using Polidocanol and Pingyangmycin Combined Foam Sclerosants	1
Near-Infrared Imaging of Indocyanine Green Identifies Novel Routes of Lymphatic Drainage from Metacarpophalangeal Joints in Healthy Human Hands	1
Computed Tomography-Based Quantitative Analysis of Fibrotic Changes in Skin and Subcutaneous Tissue in Lower Extremity Lymphedema Following Gynecologic Cancer Surgery	1

Optimal Cut-Off Value for Detecting Breast Cancer-Related Lymphedema Using Ultrasonography	1
Role of Subcutaneous Adipose Tissues in the Pathophysiology of Secondary Lymphedema	1
Staging Breast Cancer-Related Lymphedema with Bioimpedance Spectroscopy	1
Depression and Psychological Distress in Patients with Lower Extremity Lymphedema: A Mixed-Method Study	1
An Approach Toward Assessing Head-and-Neck Lymphedema Using Tissue Dielectric Constant Ratios: Method and Normal Reference Values	1
Time-Dependent Changes in the Skin Hardness in Taxane-Induced Swollen Arms	1
Complex Decongestive Therapy Improves Gait Speed in Patients with Lower Limb Lymphedema	1
Lymphatic Vascular Insufficiency and Focal Edema in Early Stages of Noncancer-Related Lymphedema	1
Research Matters	1
Application of Complete Decongestive Therapy in Patients with Secondary Bilateral Lower Limb Lymphedema after Comprehensive Treatment of Gynecological Malignant Tumor	1
Cancer-Related Lymphedema: Primary or Secondary?	1
Effect of Complex Decongestive Therapy Program on Volume and Functioning in Breast Cancer-Related Lymphedema: Global Effect and Predicting Factors	1