Assay and Drug Development Technologies

Article	Citations
On the Recent Changes to Animal Protection Measures in United States Food and Drug Administration Policy	35
Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Imaging Applications	18
Call for Special Issue Papers: New Modalities in Chemical Probes and Pharmacological Tools in Drug Discovery	16
A Perspective on Various Facets of Nanoemulsions and its Commercial Utilities	16
Beyond the Maze: Recent Advancements in Molecular and Cellular Tethered Drug Delivery Systems	13
Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Kinase Signaling	12
α-Tocopherol Polyethylene Glycol 1000 Succinate-Based Cationic Liposome for the Intracellular Delivery of Doxorubicin in MDA-MB-231 Triple-Negative Breast Cancer Cell Line	12
Novel Therapeutics Involving Antibiotic Polymer Conjugates for Treating Various Ailments: A Review	12
Silibinin-Loaded Nanostructured Lipid Carriers for Growth Inhibition of Cisplatin-Resistant Ovarian Cancer Cells	11
Acknowledgment of Reviewers 2021	11
Validation of a Novel Supercritical Fluid Extractor/Dryer Combo Instrument	11
Investigating the Role of Buzhong Yiqi Decoction on Neurogenic Bladder with Network Pharmacology, Molecular Docking, and In Vitro Assays	11
Liver-Targeting Composite Nanocarrier Delivery System Based on Chitosan Nanoparticles and Phospholipid Complexes	10
Development and Fabrication of Emodin-Loaded Patches Using Geraniol as a Penetration Enhancer for Transdermal Delivery	9
Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for Assay and Drug Development Technologies	9
Mini Review on the Lyophilization: A Basic Requirement for Formulation Development and Stability Modifier	9
Identification of Potent, Selective, and Peripherally Restricted Serotonin Receptor 2B Antagonists from a High-Throughput Screen	7
Rapid High-Throughput Assay Identified Gemcitabine and Derivatives As Potent Inhibitors Against Multidrug-Resistant Staphylococcus aureus	7
A Concise Review on Effect of PEGylation on the Properties of Lipid-Based Nanoparticles	6
Synthesis of Novel Acrylamide Graft Copolymer of Acacia nilotica Gum for the Stabilization of Melatonin Nanoparticles for Improved Therapeutic Effect: Optimization Using (3)2 Factori	6
Development and Validation of Reverse-Phase High-Performance Liquid Chromatography Based Bioanalytical Method for Estimation of Simvastatin in Rat's Plasma	6
Drug Repurposing Patent Applications October–December 2022	6
In-Silico Design, Synthesis, and Pharmacological Evaluation of Oxadiazole-Based Selective Cyclo-oxygenase-2 Inhibitors	6
Unlocking Antioxidant–Anticancer Synergy: An Exploration of Therapeutic Bioactives from Methanolic Extracts of Rubus ellipticus and Boerhavia diffusa Using HeLa Cell Line	6
A Review on Delivery and Bioavailability Enhancement Strategies of Azithromycin	5

Nanoliposomes Embedded Nanocochleates for Codelivery of Artemether and Lumefantrine: An In Vitro and In Vivo Study	5
Novel Pharmaceutical Cocrystal Consisting of Chlorzoxazone and Nicotinamide: A New Promising Carrier for Solubility Augmentation	5
In Vitro Antiviral Assays: A Review of Laboratory Methods	5
Enhanced Cytotoxic Activity of 6-Mercaptopurine–Loaded Solid Lipid Nanoparticles in Hepatic Cancer Treatment	5
Pharmacodynamic and Physicochemical Evaluation of Intranasal Zolmitriptan-Loaded Nanostructured Lipid Carriers: for Enhanced Antimigraine Potential	5
Drug Repurposing Patent Applications January–March 2023	5
Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Kinase Signaling	5
Determination of the Toxicity Preferences of Ocular Drug Delivery System by Comparing Two Different Toxicity Bioassays	4
Future Prospects and Regulatory Pathways for Invasome Technologies in Transdermal Drug Delivery	4
Repurposing of Hydroxyurea Against COVID-19: A Promising Immunomodulatory Role	4
Formulation of Lipid-Based Nanocarriers of Lacidipine for Improvement of Oral Delivery: Box-Behnken Design Optimization, In Vitro, Ex Vivo, and Preclinical Assessment	4
A Novel In Situ Gelling System of Quercetin/Sulfobutyl-Ether-β-Cyclodextrin Complex-Loaded Chitosan Nanoparticles for the Treatment of Vulvovaginitis	4
Development of Luteolin-Loaded Calcium Alginate and Gum Tragacanth Blend Microbeads for Oral Delivery: In Vitro Characterization, Antioxidant, Antimicrobial, and Anticancer Activity Against Col	4
Drug Repurposing Patent Applications July–September 2021	4
A Short Appraisal of Biomimetic Hydrogels to Improve Penetration of Poorly Permeable Drugs	4
Drug Repurposing Patent Applications: April–June 2024	4
Development of a High-Throughput Screening Assay for Small-Molecule Inhibitors of Androgen Receptor Splice Variants	3
Nanocarrier-Mediated Dermal Drug Delivery System of Antimicrobial Agents for Targeting Skin and Soft Tissue Infections	3
Letter: Addressing False Positives in High-Throughput Screening: A Call for Better Predictive Models	3
Synthesis, Antimicrobial Evaluation, and In Silico Studies of 2-Substituted-Phenyl-3-(5-Aryl/Heteroaryl Substituted Thiazol-2-yl) Thiazolidin-4-One Derivatives	3
Pharmaceutical Perspective in Wearable Drug Delivery Systems	3
Pharmacological Evaluation of Aescin for Neuroprotection in Intracerebroventricular Streptozotocin Model of Alzheimer’s Disease in Experimental Rats	3
Healing Potential of Propolis Extract–Passiflora edulis Seed Oil Emulgel Against Excisional Wound: Biochemical, Histopathological, and Cytokines Level Evidence	3
Microsponges: Development, Characterization, and Key Physicochemical Properties	3
Letter to the Editor: 3D Printing Has an Imperative Role in Colitis Management	3
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for ASSAY and Drug Development Technologies	3
Letter to the Editor: Repurposing Tafenoquine as a Potential Inhibitor Against Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease via a Fluorescence Polarization Assay	2
Enhancing Etoposide Aqueous Solubility and Anticancer Activity with L-Arginine	2
Development and In Vivo Evaluation of Pectin Based Enteric Coated Microparticles Loaded with Mesalamine and Saccharomyces boulardii for Management of Ulcerative Colitis	2
Drug Repurposing Patent Applications April–June 2021	2
Development and Method Validation of Design of Experiments-Optimized Tablet Formulation for Simultaneous Detection of Exemestane and Everolimus	2
Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools	2
Biosensor Assays Types and Their Roles Toward Ligand–Receptor Interactions in Drug Discovery	2
Drug Repurposing Patent Applications July–September 2023	2
Drug Repurposing Patent Applications March–June 2022	2
Forging Ahead with ASSAY	2
A Review on Molecular Docking As an Interpretative Tool for Molecular Targets in Disease Management	2
Preparation and Optimization of Liposome Containing Thermosensitive In Situ Nasal Hydrogel System for Brain Delivery of Sumatriptan Succinate	2
Development and Characterization of Novel Chitosan-Coated Curcumin Nanophytosomes for Treating Drug-Resistant Malaria	2
Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Kinase Signaling	1
Acknowledgment of Reviewers 2023	1
In Silico Screening of Phytochemicals as Potential Inhibitors of the JAK/STATs Pathway in Psoriasis	1
Efavirenz Loaded Mixed Polymeric Micelles: Formulation, Optimization, and In Vitro Characterization	1
Formulation and Characterization of Nanoparticulate Drug Carrier System for Lacidipine	1
Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools	1
Self-Assembled Nanomicelles to Enhance Solubility and Anticancer Activity of Etoposide	1
A Pioneer Review on Lactoferrin-Conjugated Extracellular Nanovesicles for Targeting Cellular Melanoma: Recent Advancements and Future Prospects	1
Antidiabetic Evaluation of Kigelia pinnata Root Bark Extract in Streptozotocin-Induced Type-2 Diabetes Model of Rats	1
Letter: New Horizons in Biomarker Discovery: Assay Technologies for Personalized Drug Development	1
Solid Dispersion: A Mechanistic and Realistic Approach on Antihypertensive Drug as a Drug Carrier System	1

A Genome-Edited ERα-HiBiT Fusion Reporter Cell Line for the Identification of ERα Modulators Via High-Throughput Screening and CETSA	1
A Critical Sojourn of Polymeric Micelles: Technological Concepts, Recent Advances, and Future Prospects	1
Glycerosomes: Versatile Carriers for Multi-Route Drug Delivery Systems	1
Psoriasis: Striving for Potential Biomarkers	1
Drug Repurposing Patent Applications October: December 2021	0
A Sojourn on Liposomal Delivery System: Recent Advances and Future Prospects	0
Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools	0
Feature Engineering-Assisted Drug Repurposing on Disease–Drug Transcriptome Profiles in Gastric Cancer	0
Roadmap to Cytotoxicity: Exploring Assays and Mechanisms	0
Drug Repurposing Patent Applications July–September 2022	0
Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools	0
Letter to the Editor: Concerns Regarding Ethical Issues in Reviewer Recommendations for Citations	0
Call for Special Issue Papers: Special Issue on High-throughput Technologies for the Discovery and Development of Chemical Probes and Pharmacological Tools	0
Ligandrol Ameliorates High-Fat Diet– and Streptozotocin-Induced Type 2 Diabetes Mellitus and Prevents Pancreatic Islets Degeneration	0
Latest Delivery Advancements of Lipid Nanoparticles for Cancer Treatment	0
Nanocarriers for Smart Therapeutic Strategies to Treat Drug-Resistant Tumors: A Review	0
Solubility Enhancement of Ebastine by Formulating Microemulsion Using D-Optimal Mixture Design: Optimization and Characterization	0
High-Throughput Methods for the Discovery of Small Molecule Modulators of Pancreatic Beta-Cell Function and Regeneration	0
Optimization of Lurasidone HCl-Loaded PLGA Nanoparticles for Intramuscular Delivery: Enhanced Bioavailability, Reduced Dosing Frequency, Pharmacokinetics, and Therapeutic Outcomes	0
Illuminating Insights: Clinical Study Harnessing Pharmacoscintigraphy for Permeation Study of Radiolabeled Nimesulide Topical Formulation in Healthy Human Volunteers	0
Drug Repurposing Patent Applications January–March 2024	0
Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Kinase Signaling	0
Re: “Letter to the Editor: Repurposing of an Antisepsis Drug in COVID-19 Patients,” by Kumar et al.	0
Quality by Design Approach for Optimization of Microbial and pH-Triggered Colon-Targeted Tablet Formulation Using Carboxymethyl Tamarind Gum	0
Exploration of the Mechanism of Shengxian Decoction Against Chronic Obstructive Pulmonary Disease Based on Network Pharmacology and Experimental Verification	0
Evolution of Solid Dispersion Technology: Solubility Enhancement Using Hydroxypropyl Methylcellulose Acetate Succinate: Myth or Reality?	0
Honokiol-Loaded Methoxy Poly (Ethylene Glycol) Polycaprolactone Micelles for the Treatment of Age-Related Macular Degeneration	0
Development and Validation of High-Performance Liquid Chromatography Method for the Quantification of Remdesivir in Intravenous Dosage Form	0
Correction to: Enhanced Cytotoxic Activity of 6-Mercaptopurine–Loaded Solid Lipid Nanoparticles in Hepatic Cancer Treatment, by Ergin, et al. Assay Drug Dev Technol. 2023;21(5):212–221;	0
Editorial: A New Chapter in Assay and Drug Development Technologies	0
Formulation and Characterization of Nanostructured Lipid Carriers of Rizatriptan Benzoate-Loaded In Situ Nasal Gel for Brain Targeting	0
Acknowledgment of Reviewers 2024	0
AXTEX-4D: A Three-DimensionalEx VivoPlatform for Preclinical Investigations of Immunotherapy Agents	0
Repurposing Psychotropic Agents for Viral Disorders: Beyond Covid	0
Drug Repurposing Patent Applications April–June 2023	0
Development and Validation of Reverse-Phase High-Performance Liquid Chromatography Method for Simultaneous Estimation of Doxorubicin and Clotrimazole	0
Polyherbal Antiacne Gel: In Vitro Antibacterial Activity and Efficacy Evaluation Against Cutibacterium acnes	0
A New Spectral Shift-Based Method to Characterize Molecular Interactions	0
Development and Characterization of Oral Efavirenz-Loaded Nanostructured Lipid Carriers and Their Optimization with Box–Behnken Design Approach for the Neurological Disorder	0
Novel Insight into Potential Leishmanicidal Activities of Transdermal Patches ofNigella Sativa: Formulation Development, Physical Characterizations, andIn vitro/In vivoAssays	0
Optimization of Docetaxel–Zedoary Turmeric Oil Magnetic Solid Lipid Nanoparticle Preparation by Central Composite Design-Response Surface Methodology	0
Oral Gastroretentive Film of Lacidipine for the Treatment of Gastroparesis	0
Correction to: A New Spectral Shift-Based Method to Characterize Molecular Interactions, by Langer, et al. Assay Drug Dev Technol. 2022;20(2):83–94; doi: 10.1089/adt.2021.133	0
Interview with Craig W. Lindsley, PhD	0
Protective Effects of Schizochytrium Microalgal Fatty Acids on Alcoholic Liver Disease: A Network Pharmacology and In Vivo Study	0
PEGylation of Nanoemulsion Using Spontaneous Emulsification Method	0
High-Throughput DNA-Encoded Libraries Affinity Selection Platform for Binder Identification with Solid Support Protein Immobilization	0
Preparation and Optimization of Leuprolide Acetate Nanoparticles Using Response Surface Methodology: In Vitro and Ex Vivo Evaluation	0
Next-Gen Cancer Treatment: Nanotechnology-Driven siRNA Delivery Solutions	0
Modifications to the Transwell Migration/Invasion Assay Method That Eases Assay Performance and Improves the Accuracy	0
Formulation and Characterization of Raloxifene Nanostructured Lipid Carriers for Permeability and Uptake Enhancement Applications	0
Development of Topical Nanoemulgel Using Combined Therapy for Treating Psoriasis	0
Golden Therapeutic Approach to Combat Viral Diseases Using Gold Nanomaterials	0
Doxorubicin Conjugates: An Efficient Approach for Enhanced Therapeutic Efficacy with Reduced Side Effects	0
High-Throughput Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry Method Validation for the Estimation of Atorvastatin and Active Metabolites in Human Plasma	0
Deep Learning Accelerates the Development of Antimicrobial Peptides Comprising 15 Amino Acids	0
Losartan Plays a Fungistatic and Fungicidal Activity Against Candida albicans Biofilms: Drug Repurposing for Localized Candidosis	0
Drug Repurposing Patent Applications October–December 2023	0
Stabilization of Etoricoxib Nanosuspension Using Acacia chundra Gum and Copolymers: Preparation, Characterization, and In Vitro Cytotoxic Study	0
Nano Spray-Dried Drugs for Oral Administration: A Review	0
Design, Synthesis, and Biological Evaluation of Novel Dihydropyrimidinone Derivatives as Potential Anticancer Agents and Tubulin Polymerization Inhibitors	0
Antifungal Effects of Voriconazole-Loaded Nano-Liposome on Fluconazole-Resistant Clinical Isolates of Candida albicans, Biological Activity and ERG11, CDR1, and CDR2 Gene E	0
Elucidating Genetic and Immunological Pathways Mediated by Sodium-Glucose Transporter 2 Inhibitors in Reducing Gout Risk: A Two-Step Mendelian Randomization Study	0
Preparation, Characterization, and In Vitro Evaluation of Chlorogenic Acid Loaded Hydrogel Beads for the Management of Ulcerative Colitis	0
Exosomes: Key Players for Treatment of Cancer and Their Future Perspectives	0
Enhanced Anticancer Efficiency of Curcumin Co-Loaded Lawsone Solid Lipid Nanoparticles Against MCF-7 Breast Cancer Cell Lines: Optimization by Statistical JMP Software-Based Experimental Approach	0
Drug Repurposing Patent Applications January–March 2021	0
Letter to the Editor: Repurposing of an Antisepsis Drug in COVID-19 Patients	0
Implementation of Quality by Design Approaches for Development and Validation of Reverse-Phase High-Performance Liquid Chromatography Assay Method for Determination of Glycyrrhizin in Nanoformulation	0
Pharmaceutical Methods for Enhancing the Dissolution of Poorly Water-Soluble Drugs	0
Dual Acting Immuno-Antibiotics: Computational Investigation on Antibacterial Efficacy of Immune Boosters Against Isoprenoid H Enzyme	0
TWIST1 Promotes Colorectal Carcinoma Stemness and Oxaliplatin Resistance by Activating Microfibrillar-Associated Protein 2	0
Automated Assays to Identify Modulators of Transcription Factor EB Translocation and Autophagy	0
Activities of Nanoparticles Against Fluconazole-Resistant Candida parapsilosis in Clinical Isolates	0
Call for Special Issue Papers: Chemical Probes and Pharmacological Tools for Kinase Signaling	0
A Time of Transition: Looking Back with Gratitude, Forward with Optimism	0
Utilization of an Intracellular Calcium Mobilization Assay for the Screening of Transduced FK506-Binding Proteins	0
Drug Repurposing Patent Applications July–September 2024	0
Design, Synthesis, Molecular Docking, and Biological Evaluation of Isatin-Based Fused Heterocycles As Epidermal Growth Factor Receptor Inhibitors	0
Computational Design of Phosphatidylinositol 3-Kinase Inhibitors	0

Implementation of the Box–Behnken Design in the Development and Optimization of Methotrexate-Loaded Microsponges for Colon Cancer	0
Potential of Nanocarrier-Associated Approaches for Better Therapeutic Intervention in the Management of Glioblastoma	0
Quality by Design Assisted Development of Luliconazole Transethosomes in Gel for the Management of Candida albicans Infection	0
Correction to: Novel Insight into Potential Leishmanicidal Activities of Transdermal Patches of Nigella Sativa: Formulation Development, Physical Characterizations, and In vitro/In vivo	0
Editor's Response to a Letter on “3D Printing Has an Imperative Role in Colitis Management” by Sahoo and Singh	0
Acknowledgment of Reviewers 2022	0
Reverse Phase-High-Performance Liquid Chromatography (RP-HPLC) Method Development and Validation Using Analytical Quality-by-Design Approach for Determination of Isoliquiritigenin in Bulk and Biologic	0
Determination of Microstructural Impact on the Release of Drug from Hydroxypropyl Cellulose Gel by Validated In Vitro Release Test Method	0
Adjusting the Fitting of Fluorescence-Based Dose–Response Kinase Inhibition Assay to Account for Fluorescent Inhibitors	0
Potential Assessment of Topical Felbinac-Loaded Cubosomal Gel in Soft Tissue Injury in Albino Rats	0
Call for Papers: ASSAY and Drug Development Technologies	0
Letter to the Editor: Implementation of Acoustic Dispensing and 384-Well Based Workflows to Improve Assay Capacity and Reduce Compound and Solvent Use in Early Drug Metabolism and Pharmacokinet	0
Developmental Cardiotoxicity and Hepatotoxicity of Flurbiprofen Axetil to Zebrafish Embryo	0
Drug Repurposing Patent Applications January–March 2022	0
Recent Trends in Drug Delivery Systems	0
Screening of Atherosclerotic Druggable Targets from the Proteome Network of Differentially Expressed Genes	0
MiR-22-3p Inhibits 5-Fluorouracil Resistance in Cholangiocarcinoma Cells Through PTEN/PI3K/AKT Axis	0