Molecular Cancer Research

Papers
(The TQCC of Molecular Cancer Research is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Selected Articles from This Issue196
Retraction: Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis64
Retraction: miRNA-302b Suppresses Human Hepatocellular Carcinoma by Targeting AKT253
RNF6 Inhibits Lung Adenocarcinoma Cell Proliferation by Promoting Cyclin D2 Degradation45
Selected Articles from This Issue37
MUC1-C Dictates JUN and BAF-Mediated Chromatin Remodeling at Enhancer Signatures in Cancer Stem Cells37
Selected Articles from This Issue36
Genomic Landscape of Primary and Recurrent Anal Squamous Cell Carcinomas in Relation to HPV Integration, Copy-Number Variation, and DNA Damage Response Genes36
Selected Articles from This Issue34
Editor's Note: Focal Adhesion Kinase Controls Aggressive Phenotype of Androgen-Independent Prostate Cancer34
Selected Articles from This Issue33
Acknowledgment to Reviewers33
Deregulation of AKT–mTOR Signaling Contributes to Chemoradiation Resistance in Lung Squamous Cell Carcinoma32
Glioblastoma–Astrocyte Connexin 43 Gap Junctions Promote Tumor Invasion32
Mechanical Stress Signaling in Pancreatic Cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via Rac1/cdc42/Myosin II31
Selected Articles from This Issue31
DR5 disulfide bonding functions as a sensor and effector of protein folding stress31
Correction: Demethylation of the SFRP4 Promoter Drives Gastric Cancer Progression via the Wnt Pathway30
Correction: Circular RNA ciRS-7 Maintains Metastatic Phenotypes as a ceRNA of miR-1299 to Target MMPs28
Genome Instability Precedes Viral Integration in Human Papillomavirus–Transformed Tonsillar Keratinocytes26
DNA-PK Inhibition and Radiation Promote Antitumoral Immunity through RNA Polymerase III in Pancreatic Cancer26
Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer26
TEAD2 Promotes Hepatocellular Carcinoma Development and Sorafenib Resistance via TAK1 Transcriptional Activation26
Editor’s Note: Targeting Activating Transcription Factor 3 by Galectin-9 Induces Apoptosis and Overcomes Various Types of Treatment Resistance in Chronic Myelogenous Leukemia26
Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism25
The Role of the Gut Microbiome in Hematological Cancers25
Loss of PBRM1 Alters Promoter Histone Modifications and Activates ALDH1A1 to Drive Renal Cell Carcinoma25
KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer25
The AACR Journals: Advancing Progress Toward the AACR's 115-Year Mission25
The Complex Regulation of Cytokinesis upon Abscission Checkpoint Activation24
An Endosomal Acid-Regulatory Feedback System Rewires Cytosolic cAMP Metabolism and Drives Tumor Progression24
Mechanisms of Glioblastoma Replication: Ca2+ Flares and Cl− Currents23
PIGA Mutations and Glycosylphosphatidylinositol Anchor Dysregulation in Polyposis-Associated Duodenal Tumorigenesis22
Kinesin Facilitates Phenotypic Targeting of Therapeutic Resistance in Advanced Prostate Cancer22
Chk1 Inhibition Potently Blocks STAT3 Tyrosine705 Phosphorylation, DNA-Binding Activity, and Activation of Downstream Targets in Human Multiple Myeloma Cells20
Gram-Negative Microflora Dysbiosis Facilitates Tumor Progression and Immune Evasion by Activating the CCL3/CCL5–CCR1–MAPK–PD-L1 Pathway in Esophageal Squamous Cell Carcinoma20
Radium-223–Induced Bystander Effects Cause DNA Damage and Apoptosis in Disseminated Tumor Cells in Bone Marrow19
Monoallelic IDH1 R132H Mutation Mediates Glioma Cell Response to Anticancer Therapies via Induction of Senescence19
In VitroInsertional Mutagenesis Screen Identifies Novel Genes Driving Breast Cancer Metastasis19
p53 Frameshift Mutations Couple Loss-of-Function with Unique Neomorphic Activities19
Transglutaminase 2 Maintains Hepatocyte Growth Factor Signaling to Enhance the Cancer Cell Phenotype19
Identification of a Novel FUS/ETV4 Fusion and Comparative Analysis with Other Ewing Sarcoma Fusion Proteins18
Ecdysoneless Protein Regulates Viral and Cellular mRNA Splicing to Promote Cervical Oncogenesis18
Bemcentinib and Gilteritinib Inhibit Cell Growth and Impair the Endo-Lysosomal and Autophagy Systems in an AXL-Independent Manner18
XIAP and PHB1 Regulate Anoikis through Competitive Binding to TRAF617
Malignant Progression of an Ancestral Bone Marrow Clone Harboring aCIC-NUTM2AFusion in Isolated Myeloid Sarcoma17
GATM-Mediated Creatine Biosynthesis Enables Maintenance of FLT3-ITD–Mutant Acute Myeloid Leukemia17
A Recurrent ADPRHL1 Germline Mutation Activates PARP1 and Confers Prostate Cancer Risk in African American Families17
Emerging Roles of the Copper–CTR1 Axis in Tumorigenesis17
Suppression of SIN3A by miR-183 Promotes Breast Cancer Metastasis17
LINC00239 Interacts with C-Myc Promoter-Binding Protein-1 (MBP-1) to Promote Expression of C-Myc in Esophageal Squamous Cell Carcinoma16
Raptinal Induces Gasdermin E–Dependent Pyroptosis in Naïve and Therapy-Resistant Melanoma16
Mutant p53 Attenuates Oxidative Phosphorylation and Facilitates Cancer Stemness through Downregulating miR-200c–PCK2 Axis in Basal-Like Breast Cancer16
The PI3K/mTOR Inhibitor Ompalisib Suppresses Nonhomologous End Joining and Sensitizes Cancer Cells to Radio- and Chemotherapy16
Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer16
Targeting c-Jun Is a Potential Therapy for Luminal Breast Cancer Bone Metastasis16
Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia16
Improved Delineation of Colorectal Cancer Molecular Subtypes and Functional Profiles with a 62-Gene Panel16
Metabolic Imaging as a Tool to Characterize Chemoresistance and Guide Therapy in Triple-Negative Breast Cancer (TNBC)16
Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer16
Surgical Tumor Resection Deregulates Hallmarks of Cancer in Resected Tissue and the Surrounding Microenvironment16
R-Loop–Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin16
FATP5 Is Indispensable for the Growth of Intrahepatic Cholangiocarcinoma16
Activation of the JAK/STAT Pathway Leads to BRAF Inhibitor Resistance in BRAFV600E Positive Thyroid Carcinoma15
ROR2/Wnt5a Signaling Regulates Directional Cell Migration and Early Tumor Cell Invasion in Ovarian Cancer15
ETS1, a Target Gene of the EWSR1::FLI1 Fusion Oncoprotein, Regulates the Expression of the Focal Adhesion Protein TENSIN315
Longitudinal Analysis of Human Pancreatic Adenocarcinoma Development Reveals Transient Gene Expression Signatures15
Platelet-Coated Circulating Tumor Cells Are a Predictive Biomarker in Patients with Metastatic Castrate-Resistant Prostate Cancer15
SIRT2 Regulates the SMARCB1 Loss-Driven Differentiation Block in ATRT15
USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma15
Vasorin Exocytosed from Glioma Cells Facilitates Angiogenesis via VEGFR2/AKT Signaling Pathway15
Selected Articles from This Issue14
TGF-β-Induced FLRT3 Attenuation Is Essential for Cancer-Associated Fibroblast–Mediated Epithelial–Mesenchymal Transition in Colorectal Cancer14
SynPathy: Predicting Drug Synergy through Drug-Associated Pathways Using Deep Learning14
Extrachromosomal DNA Dynamics Contribute to Intratumoral Receptor Tyrosine Kinase Genetic Heterogeneity and Drug Resistance in Gastric Cancer14
Peritoneal Microenvironment Promotes Appendiceal Adenocarcinoma Growth: A Multi-omics Approach Using Patient-Derived Xenografts14
The Androgen Receptor Does Not Directly Regulate the Transcription of DNA Damage Response Genes14
Monounsaturated Fatty Acids: Key Regulators of Cell Viability and Intracellular Signaling in Cancer14
Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer14
Critical Role of 6-Phosphogluconate Dehydrogenase in TAp73-Mediated Cancer Cell Proliferation14
Significance of RB Loss in Unlocking Phenotypic Plasticity in Advanced Cancers14
Clinically Relevant Humanized Mouse Models of Metastatic Prostate Cancer Facilitate Therapeutic Evaluation14
Constitutive β-Catenin Overexpression Represses Lncrna MIR100HG Transcription via HDAC6-Mediated Histone Modification in Colorectal Cancer14
DOT1 L Regulates Ovarian Cancer Stem Cells by Activating β-catenin Signaling14
The Spatial Context of Tumor-Infiltrating Immune Cells Associates with Improved Ovarian Cancer Survival14
Desmoglein 2 Functions as a Receptor for Fatty Acid Binding Protein 4 in Breast Cancer Epithelial Cells14
Bmal1-Mediated Circadian MELK Expression Potentiates MELK Inhibitor Chronotherapy for Esophageal Cancer13
MYC Hyperactivates Wnt Signaling in APC/CTNNB1-Mutated Colorectal Cancer Cells through miR-92a–Dependent Repression of DKK313
Exosomal lncRNA NEAT1 Inhibits NK-Cell Activity to Promote Multiple Myeloma Cell Immune Escape via an EZH2/PBX1 Axis13
Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities13
Selected Articles from This Issue13
Metabolic Inhibition Induces Pyroptosis in Uveal Melanoma13
Acknowledgment to Reviewers13
Selected Articles from This Issue13
Selected Articles from This Issue12
MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production12
Concurrent Disruption of the Ras/MAPK and NF-κB Pathways Induces Circadian Deregulation and Hepatocarcinogenesis12
Selected Articles from This Issue12
Cells in the Polyaneuploid Cancer Cell State Are Prometastatic12
Selected Articles from This Issue12
Building Tools for Machine Learning and Artificial Intelligence in Cancer Research: Best Practices and a Case Study with the PathML Toolkit for Computational Pathology12
Retraction: Histone Demethylase JMJD1A Promotes Tumor Progression via Activating Snail in Prostate Cancer12
Exome Sequencing Reveals a Sparse Genomic Landscape in Kaposi Sarcoma12
Sox2 Is an Oncogenic Driver of Small-Cell Lung Cancer and Promotes the Classic Neuroendocrine Subtype12
Correction: OLR1 Promotes Pancreatic Cancer Metastasis via Increased c-Myc Expression and Transcription of HMGA212
Exosomal CD47 Plays an Essential Role in Immune Evasion in Ovarian Cancer12
BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis12
Selected Articles from This Issue12
Functional Characterization of lncRNA152 as an Angiogenesis-Inhibiting Tumor Suppressor in Triple-Negative Breast Cancers11
Circ_0001821 Affects Proliferation and the Cell Cycle in Esophageal Squamous Cell Carcinoma by Elevating BTRC-Mediated IKBA Ubiquitination11
AMPK Associates with Chromatin and Phosphorylates the TAF-1 Subunit of the Transcription Initiation Complex to Regulate Histone Gene Expression in ALL Cells11
PPM1D in Solid and Hematologic Malignancies: Friend and Foe?11
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS111
Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma11
Correction: Histone Demethylase JMJD1A Promotes Tumor Progression via Activating Snail in Prostate Cancer11
HIPK2 Cooperates with KRAS Signaling and Associates with Colorectal Cancer Progression11
Tumor-Derived CCL5 Recruits Cancer-Associated Fibroblasts and Promotes Tumor Cell Proliferation in Esophageal Squamous Cell Carcinoma11
Oncostatin-M and OSM-Receptor Feed-Forward Activation of MAPK Induces Separable Stem-like and Mesenchymal Programs11
Canonical and Nuclear mTOR Specify Distinct Transcriptional Programs in Androgen-Dependent Prostate Cancer Cells10
SOHLH2 Suppresses Angiogenesis by Downregulating HIF1α Expression in Breast Cancer10
Single-Cell Transcriptomics Reveals Pre-existing COVID-19 Vulnerability Factors in Lung Cancer Patients10
ADAM Metallopeptidase Domain 12 Facilitates Colorectal Cancer Progression by Inhibiting Hippo Signaling Pathway Activity10
c-Myc, AKT, Hsc70, and the T-Box Transcription Factor TBX3 Form an Important Oncogenic Signaling Axis in Breast Cancer10
Progress in the Understanding of Estrogen Receptor Alpha Signaling in Triple-Negative Breast Cancer: Reactivation of Silenced ER-α and Signaling through ER-α3610
Expanding Our Horizon to Inform Cutting Edge Mechanistic Studies: Cancer Research Resources10
MAP3K7 Loss Drives Enhanced Androgen Signaling and Independently Confers Risk of Recurrence in Prostate Cancer with Joint Loss of CHD110
Distinct Transcriptional Programs in Ascitic and Solid Cancer Cells Induce Different Responses to Chemotherapy in High-Grade Serous Ovarian Cancer10
Generating a Murine PTEN Null Cell Line to Discover the Key Role of p110β-PAK1 in Castration-Resistant Prostate Cancer Invasion10
Non-Essential Amino Acid Availability Influences Proteostasis and Breast Cancer Cell Survival During Proteotoxic Stress10
Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor10
Protein Kinase D–Dependent Downregulation of Immediate Early Genes through Class IIA Histone Deacetylases in Acute Lymphoblastic Leukemia10
HMGN5 Escorts Oncogenic STAT3 Signaling by Regulating the Chromatin Landscape in Breast Cancer Tumorigenesis9
lncRNA BORG:TRIM28 Complexes Drive Metastatic Progression by Inducing α6 Integrin/CD49f Expression in Breast Cancer Stem Cells9
Telomerase Upregulation Induces Progression of Mouse BrafV600E-Driven Thyroid Cancers and Triggers Nontelomeric Effects9
Intra- and Extrahepatic Cholangiocarcinomas Display Differing Sensitivities to NK Cell Lysis and Modulate NK Cell Function through Shared and Distinct Pathways9
Heterogeneity and Cancer-Related Features in Lymphangioleiomyomatosis Cells and Tissue9
Reg4 Interacts with CD44 to Regulate Proliferation and Stemness of Colorectal and Pancreatic Cancer Cells9
Podoplanin Drives Amoeboid Invasion in Canine and Human Mucosal Melanoma9
Early Immune Changes Support Signet Ring Cell Dormancy in CDH1-Driven Hereditary Diffuse Gastric Carcinogenesis9
Nestin Is Required for Spindle Assembly and Cell-Cycle Progression in Glioblastoma Cells9
ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression9
The Role of AKT in Soft Tissue Sarcoma: Review and Insights9
Hepatitis B Virus X Protein Represses Expression of Tumor Suppressor PTPN18 in Hepatocellular Carcinoma9
Neo-Darwinian Principles Exemplified in Cancer Genomics9
Neem Leaf Glycoprotein Disrupts Exhausted CD8+ T-Cell–Mediated Cancer Stem Cell Aggression9
A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance9
O-GlcNAcylation of Blimp-1 in Lymphocytes Inhibits Its Transcriptional Function and Is Associated with Migration and Invasion of Breast Cancer Cells9
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