Molecular Cancer Research

Papers
(The TQCC of Molecular Cancer Research is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Selected Articles from This Issue528
The AACR Journals: Advancing Progress Toward the AACR's 115-Year Mission54
The Role of the Gut Microbiome in Hematological Cancers51
MIG-6 Regulates HDAC1-Mediated Angiogenesis and Tumorigenesis in PTEN-Deficient Endometrioid Endometrial Cancer42
TEAD2 Promotes Hepatocellular Carcinoma Development and Sorafenib Resistance via TAK1 Transcriptional Activation40
Vasorin Exocytosed from Glioma Cells Facilitates Angiogenesis via VEGFR2/AKT Signaling Pathway37
Clinically Relevant Humanized Mouse Models of Metastatic Prostate Cancer Facilitate Therapeutic Evaluation33
Kinesin Facilitates Phenotypic Targeting of Therapeutic Resistance in Advanced Prostate Cancer32
Mitochondrial HSP90 Paralog TRAP1 Deletion Drives Glutamine Addiction in Tumor Cells via Destablization of the Cys/Glu Antiporter SLC7A11/xCT31
Improved Delineation of Colorectal Cancer Molecular Subtypes and Functional Profiles with a 62-Gene Panel31
Malignant Progression of an Ancestral Bone Marrow Clone Harboring a CIC-NUTM2A Fusion in Isolated Myeloid Sarcoma30
Bmal1-Mediated Circadian MELK Expression Potentiates MELK Inhibitor Chronotherapy for Esophageal Cancer29
Fucosylated N-Glycan Landscape of Triple-Negative Breast Cancer28
PIGA Mutations and Glycosylphosphatidylinositol Anchor Dysregulation in Polyposis-Associated Duodenal Tumorigenesis28
Correction: Demethylation of the SFRP4 Promoter Drives Gastric Cancer Progression via the Wnt Pathway27
Exosomal lncRNA NEAT1 Inhibits NK-Cell Activity to Promote Multiple Myeloma Cell Immune Escape via an EZH2/PBX1 Axis26
Ecdysoneless Overexpression Drives Mammary Tumorigenesis through Upregulation of C-MYC and Glucose Metabolism26
A Recurrent ADPRHL1 Germline Mutation Activates PARP1 and Confers Prostate Cancer Risk in African American Families25
Comparative ASCL1 interactome analysis reveals CDK2-Cyclin A2 as suppressors of differentiation in MYCN-amplified neuroblastoma24
Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer24
Peritoneal Microenvironment Promotes Appendiceal Adenocarcinoma Growth: A Multi-omics Approach Using Patient-Derived Xenografts24
Long Noncoding RNA MSL3P1 Regulates CUL3 mRNA Cytoplasmic Transport and Stability and Promotes Lung Adenocarcinoma Metastasis23
Selected Articles from This Issue23
Gram-Negative Microflora Dysbiosis Facilitates Tumor Progression and Immune Evasion by Activating the CCL3/CCL5–CCR1–MAPK–PD-L1 Pathway in Esophageal Squamous Cell Carcinoma23
Selected Articles from This Issue22
Circ_0001821 Affects Proliferation and the Cell Cycle in Esophageal Squamous Cell Carcinoma by Elevating BTRC-Mediated IKBA Ubiquitination22
MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production22
A Novel Tumor-Promoting Role for Nuclear Factor IX in Glioblastoma Is Mediated through Transcriptional Activation of GINS122
UBE2B Drives NF-κB Signaling and Gastric Cancer Progression through BIRC2-Mediated K63-Linked Ubiquitination of TRAF122
PRMT5 Maintains Tumor Stem Cells to Promote Pediatric High-Grade Glioma Tumorigenesis21
The Role of AKT in Soft Tissue Sarcoma: Review and Insights21
MYC/Glutamine Dependency Is a Therapeutic Vulnerability in Pancreatic Cancer with Deoxycytidine Kinase Inactivation-Induced Gemcitabine Resistance21
Acknowledgment to Reviewers21
Neo-Darwinian Principles Exemplified in Cancer Genomics21
Selected Articles from This Issue20
LINC01235 Is an Upstream Regulator of the NFIB Gene and the Notch Pathway in Triple-Negative Breast Cancer19
Oncogenic GNAS Uses PKA-Dependent and Independent Mechanisms to Induce Cell Proliferation in Human Pancreatic Ductal and Acinar Organoids19
Correction: The YAP1 Signaling Inhibitors, Verteporfin and CA3, Suppress the Mesothelioma Cancer Stem Cell Phenotype19
miR-217 Regulates Normal and Tumor Cell Fate Following Induction of Endoplasmic Reticulum Stress19
Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma19
USP44 Overexpression Drives a MYC-Like Gene Expression Program in Neuroblastoma through Epigenetic Reprogramming19
Y Chromosome Loss and Implications for Oncology18
Coregulation of NDC80 Complex Subunits Determines the Fidelity of the Spindle-Assembly Checkpoint and Mitosis18
Tumor-Suppressive and Immune-Stimulating Roles of Cholesterol 25-hydroxylase in Pancreatic Cancer Cells18
ZEB1 Is Regulated by K811 Acetylation to Promote Stability, NuRD Complex Interactions, EMT, and NSCLC Metastasis17
miR-497 Target Gene Regulatory Network in Angiosarcoma17
Selected Articles from This Issue16
Genomic Profile and Clinicopathologic Analyses of Wild-Type Gastrointestinal Stromal Tumors16
Selected Articles from This Issue16
Intrinsic Epigenetic State of Primary Osteosarcoma Drives Metastasis16
Selected Articles from This Issue16
Myeloid-Derived Suppressor Cells: Orchestrators of Tumor Immune Evasion and Therapeutic Vulnerabilities16
Selected Articles from This Issue15
Epigenetic Dysregulation of Retrotransposons in Cancer15
Allele-Specific Gene Regulation, Phenotypes, and Therapeutic Vulnerabilities in Estrogen Receptor Alpha–Mutant Endometrial Cancer15
Acknowledgment to Reviewers15
Single-Cell RNA-Seq Analysis of Patient Myeloid-Derived Suppressor Cells and the Response to Inhibition of Bruton's Tyrosine Kinase15
The LINC00519/hsa- miR- 22- 3p/MECOM Axis Accelerates Intrahepatic Chola15
Lysosomal–Mitochondrial Interaction Promotes Tumor Growth in Squamous Cell Carcinoma of the Head and Neck15
Correction: Differential Control of Growth and Identity by HNF4α Isoforms in Pancreatic Ductal Adenocarcinoma14
Selected Articles from This Issue14
ASAP1 and ARF1 Regulate Myogenic Differentiation in Rhabdomyosarcoma by Modulating TAZ Activity14
Bone Metastatic Progression of Prostate Cancer Is Regulated by TRIM28–LDHA-Mediated Metabolism14
Selected Articles from This Issue14
Evolutionary Characteristics and Immunologic Divergence of Lung and Brain Metastasis Lesions in NSCLC14
A Novel Role of Prostate-Specific Membrane Antigen in Telomere Stability in Prostate Cancer Cells13
EPAC Regulates Melanoma Growth by Stimulating mTORC1 Signaling and Loss of EPAC Signaling Dependence Correlates with Melanoma Progression13
Cytokeratins 5 and 17 Maintain an Aggressive Epithelial State in Basal-Like Breast Cancer13
MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion13
Nrf2 Drives Hepatocellular Carcinoma Progression through Acetyl-CoA–Mediated Metabolic and Epigenetic Regulatory Networks13
Metabolic Hallmarks for Purine Nucleotide Biosynthesis in Small Cell Lung Carcinoma13
Semi-Supervised, Attention-Based Deep Learning for Predicting TMPRSS2:ERG Fusion Status in Prostate Cancer Using Whole Slide Images13
PKCδ Regulates Chromatin Remodeling and DNA Repair through SIRT613
Low- and High-Grade Glioma-Associated Vascular Cells Differentially Regulate Tumor Growth13
Connecting the Cell Cycle to Lipid Metabolism in Cancer: Their Reciprocal Roles and Opportunity for Therapeutic Exploitation13
HCK Promotes High-Grade Serous Ovarian Cancer Tumorigenesis through CD44 and NOTCH3 Signaling13
Bone Marrow Mesenchymal Stem Cells Induce Metabolic Plasticity in Estrogen Receptor–Positive Breast Cancer13
ANGEL2 Modulates Wild-type TP53 Translation and Doxorubicin Chemosensitivity in Colon Cancer12
Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant KRAS Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Functio12
DNA Methyltransferase 3B–Mediated Intratumoral Heterogeneity and Therapeutic Targeting in Breast Cancer Recurrence and Metastasis12
IL-9 Promotes Migratory Dissemination of Malignant T Cells by Activating the HIF-1α–Cofilin-1 Axis in Cutaneous T-cell Lymphoma12
Phosphoproteomics Reveals the Role of Constitutive KAP1 Phosphorylation by B-cell Receptor Signaling in Chronic Lymphocytic Leukemia12
JMJD6 Shapes a Pro-tumor Microenvironment via ANXA1-Dependent Macrophage Polarization in Breast Cancer12
Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response12
LINC00869 Promotes Hepatocellular Carcinoma Metastasis via Protrusion Formation12
m6A-Modified SFTA1P Acts as a Tumor Suppressor in Non–Small Cell Lung Cancer by Regulating TGFBR2 and P-TEFb12
Pan-Cancer HLA Gene-Mediated Tumor Immunogenicity and Immune Evasion12
Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia11
EHMT1/2 Inhibition Promotes Regression of Therapy-Resistant Ovarian Cancer Tumors in a CD8 T-cell–Dependent Manner11
An Endosomal Acid-Regulatory Feedback System Rewires Cytosolic cAMP Metabolism and Drives Tumor Progression11
The Androgen Receptor Does Not Directly Regulate the Transcription of DNA Damage Response Genes11
Selected Articles from This Issue11
Landscape of Allele-Specific Expression in Prostate Cancer Reveals Recurrent, Stage-Specific Events in AR Signaling and Resistance Pathways11
SMARCA4 Loss Promotes Late-Stage Tumor Progression in Nonneuroendocrine Small Cell Lung Cancer11
Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts11
Selected Articles from This Issue11
In Vitro Insertional Mutagenesis Screen Identifies Novel Genes Driving Breast Cancer Metastasis11
ETS1-Driven Transcriptional Activation of USP43 Promotes Lenvatinib Resistance in Hepatocellular Carcinoma through MYH9 Stabilization and AKT/BAD Signaling10
Extrachromosomal DNA Dynamics Contribute to Intratumoral Receptor Tyrosine Kinase Genetic Heterogeneity and Drug Resistance in Gastric Cancer10
Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma10
Selected Articles from This Issue10
Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma10
ADAM Metallopeptidase Domain 12 Facilitates Colorectal Cancer Progression by Inhibiting Hippo Signaling Pathway Activity10
Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities10
Editor’s Note: Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors10
Differential Control of Growth and Identity by HNF4α Isoforms in Pancreatic Ductal Adenocarcinoma10
Modeling Molecular Pathogenesis of Idiopathic Pulmonary Fibrosis-Associated Lung Cancer in Mice9
Selected Articles from This Issue9
FOSL2 Regulates PD-L1 and Modulates Hormone Therapy Response Heterogeneity9
Interleukin-6 Facilitates Acute Myeloid Leukemia Chemoresistance via Mitofusin 1–Mediated Mitochondrial Fusion9
Emerging Roles of ACTL6A as an Oncogenic Hub: Transcriptional Regulation and Beyond9
Hepatitis B Virus X Protein Represses Expression of Tumor Suppressor PTPN18 in Hepatocellular Carcinoma9
LIMS2 Regulates Lung Adenocarcinoma Progression and Suppresses the Activation of Cancer-Associated Fibroblast9
MUC1-C Dictates PBRM1-Mediated Chronic Induction of Interferon Signaling, DNA Damage Resistance, and Immunosuppression in Triple-Negative Breast Cancer9
Selected Articles from This Issue9
Coevolution of Atypical BRAF and KRAS Mutations in Colorectal Tumorigenesis9
CBF-Beta Mitigates PI3K-Alpha–Specific Inhibitor Killing through PIM1 in PIK3CA -Mutant Gastric Cancer9
TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling9
PAD2-Mediated Histone Citrullination Drives Tumor Progression by Enhancing Cell Proliferation and Modifying the Microenvironment in Pancreatic Cancer9
TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP9
Kindlin-2–Mediated Hematopoiesis Remodeling Regulates Triple-Negative Breast Cancer Immune Evasion9
Inhibition of USP7 Destabilizes the Noncanonical PRC1.1 Complex and Induces Neuroblastoma Differentiation9
AMPK Associates with Chromatin and Phosphorylates the TAF-1 Subunit of the Transcription Initiation Complex to Regulate Histone Gene Expression in ALL Cells9
Loss of Regulator of G Protein Signaling 11 Promotes Protumorigenic Features in Pancreatic Cancer9
Oncostatin-M and OSM-Receptor Feed-Forward Activation of MAPK Induces Separable Stem-like and Mesenchymal Programs9
hnRNPAB Promotes Pancreatic Ductal Adenocarcinoma Extravasation and Liver Metastasis by Stabilizing MYC mRNA9
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