Ocular Surface

Article	Citations
Editorial Board	142
Reassessing interdisciplinary approaches to belantamab mafodotin-induced ocular toxicity: Towards a standardized collaborative model	123
In vivo calcium imaging of corneal sensory nerves with fluorescent stereoscopic microscopy	115
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia	85
Monkeypox and ocular implications in humans	81
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–21	73
Economic burden of keratitis patients with inpatient care: a nationwide, multicenter registry study	64
Endogenous TSG-6 modulates corneal inflammation following chemical injury	59
Atypical microbial keratitis	58
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments	58
Safety of subconjunctival injection of mesenchymal stromal cells in persistent corneal epithelial disease – A phase 1b clinical trial	56
Development and validation of a method to generate phenol red thread tests	52
Readership awareness series – Paper 10: Open Access Publishing	51
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome	49
Mechanistic insights into conjunctivalization in limbal stem cell deficiency using a lineage tracing approach	49
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study	46
Editorial Board	45
A prospective self-controlled study on the alterations of the ocular surface and conjunctival transcriptomic profile associated with prolonged exposure to video display terminals	45
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician	43
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction	40
Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia	39
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease	38
Effects of age on lacrimal gland bioactive lipids	37
Metabolic reprogramming in lacrimal gland GVHD: Stage-specific shifts in acinar cells as drivers of disease progression	35
Corneal gene therapy: Structural and mechanistic understanding	35

Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test	33
A pilot randomized controlled trial of topical androgen treatment in dry eye	33
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial	32
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model	32
Radiofrequency treatment for meibomian gland dysfunction: A randomized controlled trial	31
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis	30
Interdisciplinary management of belantamab mafodotin-associated ocular toxicity in clinical practice	29
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies	29
TFOS Lifestyle: Impact of nutrition on the ocular surface	29
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures	28
Topical low-dose heparin in ocular Stevens Johnson Syndrome and associated molecular correlations: A randomized controlled pilot study	28
A loss of inter-α-inhibitor Heavy Chain 5 (ITIH5) leads to corneal thinning and increased corneal inflammation following injury and early onset geriatric decline	28
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite	26
Cytokine levels and clinical characteristics in the tear fluid of patients with atopic dermatitis and atopic keratoconjunctivitis	26
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction	25
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface	25
Trustworthy research presentations	24
Readership awareness series – Paper 3: Paper mills	23
Keratoneuropathy	23
Expert consensus on pediatric dry eye: Insights from a European Delphi study	23
Subconjunctival triamcinolone injection for infectious necrotizing scleritis	23
Insights into the clinical development of regenerative medical products through a comparison of three cell-based products recently approved for limbal stem cell deficiency	23
Effect of cosmetics on the measurement of the tear lipid layer thickness by LipiView®	23
Redefining ocular drug delivery	22
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing	22
Label-free quantitative imaging of conjunctival goblet cells	22
Readership awareness series - Paper 6: How to write a good peer review report?	21
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study	21
Host-microbe interactions in cornea	21
Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy	21
1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface	21
Age-related dry eye disease: Redefining a distinct subtype driven by aging	21
Investigating conjunctival immune pathways in Sjögren and non-Sjögren disease associated dry eye	21
Conjunctival vessel density analysis as a marker of inflammation in dry eye disease	20
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye	20
Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study	20
A novel artificial intelligence model for diagnosing Acanthamoeba keratitis through confocal microscopy	20
Intralesional triamcinolone injection as an adjuvant therapy for refractory cicatrizing conjunctivitis	20
Visual outcomes of children undergoing penetrating keratoplasty in the US	20
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease	20
Re: Significant errors in the paper by Ballesteros-Sánchez A, Rocha-de-Lossada C and Sánchez-González J. Efficacy of eyelid warming devices as first-step treatment in meibomian gland dysfunction: A sy	20
Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining	20
Corrigendum to “Models for Meibomian gland dysfunction: In vivo and in vitro”, Review article [Ocul. Surf. 32 (2024) 154–165]	20
Identifying patient-valued outcomes for use in early phase trials of ocular surface disease interventions	20
Use of a transgenic mouse model for in vivo monitoring of corneal pathologies following Sulfur Mustard Exposure	19
Fenofibrate ameliorates ocular surface inflammation in diabetic keratopathy	19
High-resolution high-contrast in vivo phase imaging of corneal nerves and immune cells in mice	19
Smad4 deficiency ameliorates the progressive corneal stroma thinning caused by the loss of Tbr1	19
Transglutaminase-2 is critical for corneal epithelial barrier function via positive regulation of Claudin-1	18
Two models of the structures of the lamellae in human meibum and the tear film lipid layer, TFLL	18

Readership awareness series – Paper 11: Copyright licensing for scientific publications	18
Corneal complications of Sjögren's disease: Insights from a large tertiary ophthalmological care center	18
Deep learning-based classification of fungal and Acanthamoeba keratitis using confocal microscopy	18
Evaluation of ocular neuropathic pain	18
Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treating dry eye disease	18
Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond	18
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas	17
Pipeline: Ocular biostatistics: Proper use of proportions	17
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy	17
Readership awareness series - Paper 1: Ghost authorship	17
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/3	17
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]	17
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice	16
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence	16
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity	16
Exploration of imaging and molecular biomarkers for differentiation of neuropathic corneal pain from dry eye syndrome	16
Hyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium	16
Ocular graft-versus-host disease: Experience, incidence, and treatment outcomes at a university-based tertiary care ophthalmology center	16
Downregulation of the core circadian gene Nr1d2 in the lacrimal gland contributes to postoperative dry eye disease by impairing lipid metabolism	16
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study	15
Contact-mode fluorescence imaging for multi-regional assessment of conjunctival goblet cells in humans	15
Pipeline: Therapeutics – Two views of off-label use	15
The effect of botulinum neurotoxin A injections on meibomian glands and dry eye	15
IVCM image analysis for limbal stem cell deficiency: quantitative diagnostics of the corneal epithelium post-transplant recovery	15
Pipeline: US FDA efficacy requirements for treatment of ocular surface disease: Drugs vs. medical devices	15
Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity	15
Response to “Methodological considerations regarding 'Ranking the efficacy of topical treatments for ocular allergy: A network meta-analysis of current evidence'”	15
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model	15
Intelligent interferometric analysis of lipid layer thickness for clinical evaluation of dry eye disease	15
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells	15
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)	15
Editorial Board	14
Readership awareness series – Paper 7: An overview of impact factor and other scientometrics	14
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”	14
Preservatives and ocular surface disease: A review	14
Delphi panel on neuromodulation as a treatment strategy for dry eye disease: Unlocking the potential of natural tear production	13
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model	13
Intrinsic regeneration mechanisms of murine lacrimal gland epithelial cells for therapeutic applications in aqueous-deficient dry eye disease	13
Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function	13
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammation	13
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation	13
Letter to Editor: Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns	13
Endoplasmic reticulum stress contributes to the development of ocular graft-vs-host disease in the eyelids and the ocular surface	13
A novel Schirmer strip-based tear matrix metalloproteinase measurement in dry eye evaluation	13
Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair	13
Restoration of corneal epithelial barrier function: A possible target for corneal neovascularization	12
A prospective, longitudinal study to assess progression of ocular surface signs, tear cytokines and protein profiles in young adults	12
The genus decision: Potential impact on ophthalmic pharmaceuticals	12
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation	12
Editorial Board	12
Pediatric vs adult Stevens Johnson syndrome/toxic epidermal necrolysis: Ocular outcomes and the role of amniotic membrane	12
Global burden, risk factors, causative organisms and antibiotic susceptibility patterns in bacterial keratitis	12
Editorial Board	12
Glycoprotein 340 expression in hyperosmolar stress and infection of corneal epithelial cells	12
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria	11
Decoding the corneal immune microenvironment in healthy and diabetic mice during corneal wound healing	11
Umbilical cord-derived mesenchymal stem cell therapy for acute Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with severe ocular involvement	11
Readership awareness series – paper 14: The submission Dilemma - How to choose a journal?	11
Effectiveness of adult zoster vaccination in preventing a first episode of zoster keratitis: A large-scale database study	11
Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency	11
Alleviative effect of probiotics and prebiotics on dry eye in type 2 diabetic mice through the gut-eye axis	11
Cytarabine chemotherapy induces meibomian gland dysfunction	11
Remission of corneal and peripheral neuropathy after bariatric surgery in people with diabetes	11
Salivary gland transplantation for dry eye disease: Indications, techniques, and outcomes	11
Topical formulations of Aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration	11
Tear lymphotoxin-alpha deficiency is associated with conjunctival epitheliopathy in patients with dry eye disease	11
The multifaceted aspects of ocular allergies: Phenotypes and endotypes	11
Impact of botulinum toxin type A on ocular pain with neuropathic features	11
Anti-inflammatory and wound healing potential of medicinal maggot excretions/secretions at the ocular surface	11
Editorial Board	10
The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration	10
Density and distribution of dendritiform cells in the peripheral cornea of healthy subjects using in vivo confocal microscopy	10
Conditional deletion of CD25 in the corneal epithelium reveals sex differences in barrier disruption	10
Prolonged stability of 1% 5-FU eye drops as topical chemotherapy for ocular surface squamous neoplasia	10
The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study	10
Evolution of corneal cross-linking trial design and reporting for keratoconus on ClinicalTrials.gov	10
TFOS Lifestyle Report Executive Summary: A Lifestyle Epidemic - Ocular Surface Disease	10
Ocular involvement in Mycoplasma induced rash and mucositis: A systematic review of the literature	10
Lacrimal gland spheroids in tissue specific hydrogel for dry eye modelling	10
Clinical and genetic profiling of fibromyalgia-associated dry eye: A multifactorial approach	10

Electroencephalogram-detected stress levels in the frontal lobe region of patients with dry eye	10
The corneal fibroblast: The Dr. Jekyll underappreciated overseer of the responses to stromal injury	10
Readership awareness series – Paper 8: Research ethics and ‘editorial expressions of concern’	10
Editorial Board	10
Topical glaucoma medications – Clinical implications for the ocular surface	10
Letter to the Editor regarding “Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treat	10
Diagnostic capacity for fungal keratitis in Africa – Survey in 50 African countries	10
Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-37	9
Blinded by smoke: Wildfire smoke exposure and eye irritation in australian wildland firefighters	9
Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling	9
Editorial Board	9
Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels	9
Imbalanced IL-37/TNF-α/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro	9
Readership awareness series - Paper 5: The peer review process	9
Dry eye disease sustainability	9
Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease	9
A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease	8
Corneal sub-basal nerve fiber plexus tortuosity in eyes with ectasia susceptibility and keratoconus: A cross-sectional in vivo confocal microscopy study	8
Comprehensive profiling of the human tear fluid miRNome using small RNA sequencing	8
Unique cytokine signature in ocular Stevens-Johnson syndrome non-responders	8
Effects of meibomian gland dysfunction and aqueous deficiency on friction-related disease	8
A masked study to differentiate in vivo confocal microscopic features of Pythium insidiosum and fungal filaments	8
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension tria	8
Nobiletin restores corneal circadian transcriptome organization and mitigates ocular surface pathology in high-fructose-induced metabolic dysfunction	8
A novel severity scoring system for murine ocular graft versus host disease and its correlation with CD3+ T cells in the cornea	8
Herpes simplex virus-1 conjunctival dendrite in an immunosuppressed patient	8
Identification of a translatable animal model for dry eye disease using comparative analysis of tear proteins across species	8
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment	8
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial	8
Differences in pre-surgical baseline tear proteome are associated with persistent post-refractive surgery pain	8
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining	8
Self-complementary AAV vector therapy for treating corneal cloudiness of mucopolysaccharidosis type VII (MPS VII)	8
Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis	7
Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation	7
The cumulative impact of air pollution on dry eye disease: Evidence from the Korea national health and nutrition examination survey (2017-2020)	7
Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns	7
A tribute to Gary N. Foulks, M.D. (1944–2025) and his contributions to the ocular surface	7
Clinical trials submissions to The Ocular Surface	7
TFOS Lifestyle Report Introduction: A Lifestyle Epidemic - Ocular Surface Disease	7
Recurrent retroprosthetic membranes in Boston Keratoprosthesis Type I: Incidence, risk factors, and complications	7
Readership awareness series – Paper 4: Chatbots and ChatGPT - Ethical considerations in scientific publications	7
MicroRNAs in corneal Diseases: Emerging roles as biomarkers, regulators, and therapeutics	7
Readership awareness series – Paper 9: Retraction of a publication	7
The miR-183/96/182 cluster is a checkpoint for resident immune cells and shapes the cellular landscape of the cornea	7
Pipeline: Patient, physician and developer view of drugs vs. devices	7
Near complete corneal regeneration after lamellar keratoplasty in rabbits enabled by an in situ photo-crosslinkable dendrimer-hyaluronic acid hydrogel	7
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system	7
TFOS Lifestyle: Impact of the digital environment on the ocular surface	7
Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions	7
Progranulin restores diabetic corneal healing by modulating NF-κB–Driven inflammation and neuro-regenerative pathways	6
Dry eye disease in the young: A narrative review	6
Artificial Intelligence-based smartphone application for real-time blinking assessment	6
The Yin and Yang of non-immune and immune responses in meibomian gland dysfunction	6
A review of the epithelial and stromal effects of corneal collagen crosslinking	6
Editorial Board	6
Epidemiological insights into Childhood vernal keratoconjunctivitis in India: Unravelling clinical presentation and environmental influences – The EPIC VKC study – Fourth report of the ICMR EYE SEE st	6
Antibiotic resistance of Pseudomonas aeruginosa from ocular samples in Canada: a 25-year analysis	6
Prevalence and antimicrobial susceptibility pattern of coagulase-negative Staphylococci isolated from ocular infections: A systematic review and meta-analysis	6
Meibomian gland stem/progenitor cells: The hunt for gland renewal	6
The power of the adverb	6
Moxifloxacin-resistant and moxifloxacin-susceptible Staphylococcus aureus Keratitis: Outcomes from a 10-year retrospective study	6
Pipeline: The next generation of therapy for ocular surface disease	6
Management of scleral melt	6
Topical pharmacologic treatments for dry eye disease: A systematic review	6
Microsporidial keratitis: Global epidemiology, pathogen spectrum, and management	6
Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway	6
Ultrasonography assessments of meibomian gland as a noninvasive method of detecting changes in morphology	6
Proteomic profiling of tear fluid in patients with atopic keratoconjunctivitis	5
The ocular surface tear film as a biomarker for systemic health	5
Detecting dry eye from ocular surface videos based on deep learning	5
Combined blockade of VEGFR-3 and Itga-9 inhibits corneal lymphangiogenesis and valvulogenesis in vivo and promotes high-risk transplant survival	5
Matrix glycosaminoglycans and proteoglycans in human cornea organoids and similarities with fetal corneal stages	5
Corrigendum to: “Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function” [Ocul Sur	5
The prevalence and recurrence risk of bare sclera pterygium surgery in the United States	5
Calcium-sensing receptor (CaSR) modulates ocular surface chloride transport and its inhibition promotes ocular surface hydration	5
Tissue-targeted and localized AAV5-DCN and AAV5-PEDF combination gene therapy abrogates corneal fibrosis and concurrent neovascularization in rabbit eyes in vivo	5
Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain	5
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients	5
Cicatricial entropion in eyes with lid margin mucous membrane grafting	5
Pipeline: Pharmacotherapy of dry eye disease in vertebrates	5
Gene expression signatures in conjunctival fornix aspirates of patients with dry eye disease associated with Meibomian gland dysfunction. A proof-of-concept study	5
Methodological considerations regarding "Ranking the efficacy of topical treatments for ocular allergy: A network meta-analysis of current evidence" [Letter]	5
Trends in using mesenchymal stromal/stem cells (MSCs) in treating corneal diseases	5
Short chain fatty acids inhibit corneal inflammatory responses to TLR ligands via the ocular G-protein coupled receptor 43	5
What is truly evidence-based in pterygium? An umbrella review of systematic reviews and meta-analyses	5
Transitory alkali exposure on meibomian gland orifices induces meibomian gland dysfunction	5
Topical 1% 5-fluorouracil eye drops as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study	5
Big-bubble DALK: A technique in evolution	5
Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis – A review	4
Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors	4
Editorial Board	4
Was Marilyn Monroe myopic and an early adopter of colored contact lenses? A review of the evidence and the early history of colored contact lenses	4
Association of tobacco smoking with aqueous deficient and evaporative dry eye disease subtypes: a prospective registry-based case-control study	4
The roles of neural adaptation and sensitization in contact lens discomfort	4
Video frame rate influences the accuracy of blink dynamics measurement	4