Ocular Surface

Article	Citations
Editorial Board	134
Reassessing interdisciplinary approaches to belantamab mafodotin-induced ocular toxicity: Towards a standardized collaborative model	112
In vivo calcium imaging of corneal sensory nerves with fluorescent stereoscopic microscopy	106
Safety of subconjunctival injection of mesenchymal stromal cells in persistent corneal epithelial disease – A phase 1b clinical trial	76
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia	76
Monkeypox and ocular implications in humans	70
Endogenous TSG-6 modulates corneal inflammation following chemical injury	69
Atypical microbial keratitis	66
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–21	58
Development and validation of a method to generate phenol red thread tests	58
Economic burden of keratitis patients with inpatient care: a nationwide, multicenter registry study	54
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments	53
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model	50
Readership awareness series – Paper 10: Open Access Publishing	50
Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test	49
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome	46
Mechanistic insights into conjunctivalization in limbal stem cell deficiency using a lineage tracing approach	45
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders	45
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis	44
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study	43
A prospective self-controlled study on the alterations of the ocular surface and conjunctival transcriptomic profile associated with prolonged exposure to video display terminals	42
Editorial Board	40
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial	39
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician	37
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction	35

Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia	35
Metabolic reprogramming in lacrimal gland GVHD: Stage-specific shifts in acinar cells as drivers of disease progression	35
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease	34
Corneal gene therapy: Structural and mechanistic understanding	31
Effects of age on lacrimal gland bioactive lipids	31
A loss of inter-α-inhibitor Heavy Chain 5 (ITIH5) leads to corneal thinning and increased corneal inflammation following injury and early onset geriatric decline	31
A pilot randomized controlled trial of topical androgen treatment in dry eye	31
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies	31
Cytokine levels and clinical characteristics in the tear fluid of patients with atopic dermatitis and atopic keratoconjunctivitis	30
Limiting plastic waste in dry eye practice for environmental sustainability	30
Investigating the diagnostic utility of non-invasive tear film stability and breakup parameters: A prospective diagnostic accuracy study	29
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures	29
Cyclosporine A 1mg/ml in pediatric blepharokeratoconjunctivitis: Case series of 145 children and young people	29
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction	28
Interdisciplinary management of belantamab mafodotin-associated ocular toxicity in clinical practice	27
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite	27
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface	26
Topical low-dose heparin in ocular Stevens Johnson Syndrome and associated molecular correlations: A randomized controlled pilot study	26
TFOS Lifestyle: Impact of nutrition on the ocular surface	26
Keratoneuropathy	24
Effect of cosmetics on the measurement of the tear lipid layer thickness by LipiView®	24
Subconjunctival triamcinolone injection for infectious necrotizing scleritis	24
Trustworthy research presentations	24
Readership awareness series – Paper 3: Paper mills	23
Expert consensus on pediatric dry eye: Insights from a European Delphi study	22
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study	21
Label-free quantitative imaging of conjunctival goblet cells	21
Host-microbe interactions in cornea	21
1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface	21
Redefining ocular drug delivery	21
Exposure keratopathy in patients undergoing invasive ventilation: Prevalence, severity, and the role of surface lubrication	21
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing	20
Investigating conjunctival immune pathways in Sjögren and non-Sjögren disease associated dry eye	20
Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy	20
Insights into the clinical development of regenerative medical products through a comparison of three cell-based products recently approved for limbal stem cell deficiency	20
Intralesional triamcinolone injection as an adjuvant therapy for refractory cicatrizing conjunctivitis	20
Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy	20
Readership awareness series - Paper 6: How to write a good peer review report?	20
Two models of the structures of the lamellae in human meibum and the tear film lipid layer, TFLL	19
Conjunctival vessel density analysis as a marker of inflammation in dry eye disease	19
Use of a transgenic mouse model for in vivo monitoring of corneal pathologies following Sulfur Mustard Exposure	19
Re: Significant errors in the paper by Ballesteros-Sánchez A, Rocha-de-Lossada C and Sánchez-González J. Efficacy of eyelid warming devices as first-step treatment in meibomian gland dysfunction: A sy	19
A novel artificial intelligence model for diagnosing Acanthamoeba keratitis through confocal microscopy	19
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye	19
Visual outcomes of children undergoing penetrating keratoplasty in the US	18
Corneal complications of Sjögren's disease: Insights from a large tertiary ophthalmological care center	18
Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond	18
Corrigendum to “Models for Meibomian gland dysfunction: In vivo and in vitro”, Review article [Ocul. Surf. 32 (2024) 154–165]	18
Transglutaminase-2 is critical for corneal epithelial barrier function via positive regulation of Claudin-1	18
High-resolution high-contrast in vivo phase imaging of corneal nerves and immune cells in mice	18

Evaluation of ocular neuropathic pain	18
Identifying patient-valued outcomes for use in early phase trials of ocular surface disease interventions	18
Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining	18
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]	17
Smad4 deficiency ameliorates the progressive corneal stroma thinning caused by the loss of Tbr1	17
Exploration of imaging and molecular biomarkers for differentiation of neuropathic corneal pain from dry eye syndrome	17
Downregulation of the core circadian gene Nr1d2 in the lacrimal gland contributes to postoperative dry eye disease by impairing lipid metabolism	17
Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study	17
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease	17
Readership awareness series – Paper 11: Copyright licensing for scientific publications	17
Deep learning-based classification of fungal and Acanthamoeba keratitis using confocal microscopy	17
Fenofibrate ameliorates ocular surface inflammation in diabetic keratopathy	17
Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treating dry eye disease	17
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice	16
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/3	16
Readership awareness series - Paper 1: Ghost authorship	16
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)	16
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas	16
Pipeline: Ocular biostatistics: Proper use of proportions	16
The effect of botulinum neurotoxin A injections on meibomian glands and dry eye	16
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy	16
Modified technique for sutureless amniotic membrane transplantation in acute Stevens-Johnson syndrome using fibrin sealant	16
Hyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium	15
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence	15
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity	15
Ocular graft-versus-host disease: Experience, incidence, and treatment outcomes at a university-based tertiary care ophthalmology center	15
Pipeline: Therapeutics – Two views of off-label use	15
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model	14
IVCM image analysis for limbal stem cell deficiency: quantitative diagnostics of the corneal epithelium post-transplant recovery	14
Pipeline: US FDA efficacy requirements for treatment of ocular surface disease: Drugs vs. medical devices	14
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study	14
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells	14
Intelligent interferometric analysis of lipid layer thickness for clinical evaluation of dry eye disease	14
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy	14
Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity	14
Response to “Methodological considerations regarding 'Ranking the efficacy of topical treatments for ocular allergy: A network meta-analysis of current evidence'”	14
Editorial Board	13
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation	13
Preservatives and ocular surface disease: A review	13
Readership awareness series – Paper 7: An overview of impact factor and other scientometrics	13
Endoplasmic reticulum stress contributes to the development of ocular graft-vs-host disease in the eyelids and the ocular surface	13
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”	13
Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function	13
Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair	12
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation	12
Global burden, risk factors, causative organisms and antibiotic susceptibility patterns in bacterial keratitis	12
Restoration of corneal epithelial barrier function: A possible target for corneal neovascularization	12
A prospective, longitudinal study to assess progression of ocular surface signs, tear cytokines and protein profiles in young adults	12
A novel Schirmer strip-based tear matrix metalloproteinase measurement in dry eye evaluation	12
Delphi panel on neuromodulation as a treatment strategy for dry eye disease: Unlocking the potential of natural tear production	12
Editorial Board	12
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model	12
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammation	12
Letter to Editor: Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns	12
Editorial Board	12
Pediatric vs adult Stevens Johnson syndrome/toxic epidermal necrolysis: Ocular outcomes and the role of amniotic membrane	11
Topical formulations of Aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration	11
Decoding the corneal immune microenvironment in healthy and diabetic mice during corneal wound healing	11
Glycoprotein 340 expression in hyperosmolar stress and infection of corneal epithelial cells	11
Tear lymphotoxin-alpha deficiency is associated with conjunctival epitheliopathy in patients with dry eye disease	11
Cytarabine chemotherapy induces meibomian gland dysfunction	11
The genus decision: Potential impact on ophthalmic pharmaceuticals	11
Remission of corneal and peripheral neuropathy after bariatric surgery in people with diabetes	11
Umbilical cord-derived mesenchymal stem cell therapy for acute Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with severe ocular involvement	11
Effectiveness of adult zoster vaccination in preventing a first episode of zoster keratitis: A large-scale database study	11
Salivary gland transplantation for dry eye disease: Indications, techniques, and outcomes	10
Readership awareness series – paper 14: The submission Dilemma - How to choose a journal?	10
TFOS Lifestyle Report Executive Summary: A Lifestyle Epidemic - Ocular Surface Disease	10
Conditional deletion of CD25 in the corneal epithelium reveals sex differences in barrier disruption	10
Multicenter prospective validation study for international chronic ocular graft-versus-host disease consensus diagnostic criteria	10
Impact of botulinum toxin type A on ocular pain with neuropathic features	10
Density and distribution of dendritiform cells in the peripheral cornea of healthy subjects using in vivo confocal microscopy	10
Topical glaucoma medications – Clinical implications for the ocular surface	10
Anti-inflammatory and wound healing potential of medicinal maggot excretions/secretions at the ocular surface	10
Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency	10
The multifaceted aspects of ocular allergies: Phenotypes and endotypes	10
Ocular involvement in Mycoplasma induced rash and mucositis: A systematic review of the literature	10
Readership awareness series – Paper 8: Research ethics and ‘editorial expressions of concern’	10
Lacrimal gland spheroids in tissue specific hydrogel for dry eye modelling	10
Alleviative effect of probiotics and prebiotics on dry eye in type 2 diabetic mice through the gut-eye axis	10

Editorial Board	9
Ectoine protects corneal epithelial survival and barrier from hyperosmotic stress by promoting anti-inflammatory cytokine IL-37	9
Prolonged stability of 1% 5-FU eye drops as topical chemotherapy for ocular surface squamous neoplasia	9
Electroencephalogram-detected stress levels in the frontal lobe region of patients with dry eye	9
Letter to the Editor regarding “Corneal sensory nerve regulation of tear production through stimulation of transient receptor potential melastatin 8 (TRPM8) channel: A potential new approach for treat	9
The corneal fibroblast: The Dr. Jekyll underappreciated overseer of the responses to stromal injury	9
Clinical and genetic profiling of fibromyalgia-associated dry eye: A multifactorial approach	9
Relationships between ocular surface sphingomyelinases, Meibum and Tear Sphingolipids, and clinical parameters of meibomian gland dysfunction	9
The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration	9
Diagnostic capacity for fungal keratitis in Africa – Survey in 50 African countries	9
The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study	9
Editorial Board	9
A novel severity scoring system for murine ocular graft versus host disease and its correlation with CD3+ T cells in the cornea	8
Self-complementary AAV vector therapy for treating corneal cloudiness of mucopolysaccharidosis type VII (MPS VII)	8
Differences in pre-surgical baseline tear proteome are associated with persistent post-refractive surgery pain	8
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial	8
Imbalanced IL-37/TNF-α/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro	8
Dry eye disease sustainability	8
Herpes simplex virus-1 conjunctival dendrite in an immunosuppressed patient	8
Unique cytokine signature in ocular Stevens-Johnson syndrome non-responders	8
Effects of meibomian gland dysfunction and aqueous deficiency on friction-related disease	8
Readership awareness series - Paper 5: The peer review process	8
Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease	8
Patients with neurotrophic keratitis demonstrate alterations in ocular surface expression of transient receptor potential (TRP) channels	8
Fluorescein CorneoGraphy (FCG): Use of a repurposed fluorescein imaging technique to objectively standardize corneal staining	8
Comparable meibomian gland changes in patients with and without ocular graft-versus-host disease after hematopoietic stem cell transplantation	8
Blinded by smoke: Wildfire smoke exposure and eye irritation in australian wildland firefighters	8
Lacrimal gland duct obstruction and dacryops: Unravelling its pathogenesis with proteomics and cellular profiling	8
A masked study to differentiate in vivo confocal microscopic features of Pythium insidiosum and fungal filaments	7
Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension tria	7
A multicenter report of the use of plasma rich in growth factors (PRGF) for the treatment of patients with ocular surface diseases in North America	7
TFOS Lifestyle: Impact of the digital environment on the ocular surface	7
Pipeline: Patient, physician and developer view of drugs vs. devices	7
Clinical trials submissions to The Ocular Surface	7
Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment	7
Comprehensive profiling of the human tear fluid miRNome using small RNA sequencing	7
MicroRNAs in corneal Diseases: Emerging roles as biomarkers, regulators, and therapeutics	7
Readership awareness series – Paper 4: Chatbots and ChatGPT - Ethical considerations in scientific publications	7
Readership awareness series – Paper 9: Retraction of a publication	7
Topical pharmacologic treatments for dry eye disease: A systematic review	7
Prospective consecutive case series of patients with neurotrophic keratopathy associated with unilateral total limbal stem cell deficiency caused by severe ocular surface burns	7
A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease	7
The miR-183/96/182 cluster is a checkpoint for resident immune cells and shapes the cellular landscape of the cornea	7
Identification of a translatable animal model for dry eye disease using comparative analysis of tear proteins across species	7
Delayed diagnosis of ocular graft-versus-host disease after allogeneic hematopoietic stem cell transplantation	7
Management of scleral melt	7
A tribute to Gary N. Foulks, M.D. (1944–2025) and his contributions to the ocular surface	7
TFOS Lifestyle Report Introduction: A Lifestyle Epidemic - Ocular Surface Disease	6
Near complete corneal regeneration after lamellar keratoplasty in rabbits enabled by an in situ photo-crosslinkable dendrimer-hyaluronic acid hydrogel	6
Pipeline: The next generation of therapy for ocular surface disease	6
The cumulative impact of air pollution on dry eye disease: Evidence from the Korea national health and nutrition examination survey (2017-2020)	6
Meibomian gland stem/progenitor cells: The hunt for gland renewal	6
The power of the adverb	6
Novel discovery of a lymphatic bridge connecting Schlemm's canal to limbal and conjunctival lymphatic pathway	6
The Yin and Yang of non-immune and immune responses in meibomian gland dysfunction	6
Antibiotic resistance of Pseudomonas aeruginosa from ocular samples in Canada: a 25-year analysis	6
Progranulin restores diabetic corneal healing by modulating NF-κB–Driven inflammation and neuro-regenerative pathways	6
Metabolic signatures of tear extracellular vesicles caused by herpes simplex keratitis	6
Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions	6
Prevalence and antimicrobial susceptibility pattern of coagulase-negative Staphylococci isolated from ocular infections: A systematic review and meta-analysis	6
Preclinical confirmation of UVC efficacy in treating infectious keratitis	6
A review of the epithelial and stromal effects of corneal collagen crosslinking	6
Epidemiological insights into Childhood vernal keratoconjunctivitis in India: Unravelling clinical presentation and environmental influences – The EPIC VKC study – Fourth report of the ICMR EYE SEE st	6
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system	6
Dry eye disease in the young: A narrative review	6
Recurrent retroprosthetic membranes in Boston Keratoprosthesis Type I: Incidence, risk factors, and complications	6
Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients	6
Ultrasonography assessments of meibomian gland as a noninvasive method of detecting changes in morphology	6
Moxifloxacin-resistant and moxifloxacin-susceptible Staphylococcus aureus Keratitis: Outcomes from a 10-year retrospective study	6
Tissue-targeted and localized AAV5-DCN and AAV5-PEDF combination gene therapy abrogates corneal fibrosis and concurrent neovascularization in rabbit eyes in vivo	5
Calcium-sensing receptor (CaSR) modulates ocular surface chloride transport and its inhibition promotes ocular surface hydration	5
New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering	5
Heightened visual light sensitivity discomfort measured by the ocular photosensitivity analyzer is associated with chronic ocular pain	5
Detecting dry eye from ocular surface videos based on deep learning	5
Neurotrophic Keratitis: A rare disease that requires proactive screening and orphan drug treatments	5
The ocular surface tear film as a biomarker for systemic health	5
Trends in using mesenchymal stromal/stem cells (MSCs) in treating corneal diseases	5
Methodological considerations regarding "Ranking the efficacy of topical treatments for ocular allergy: A network meta-analysis of current evidence" [Letter]	5
The prevalence and recurrence risk of bare sclera pterygium surgery in the United States	5
Topical 1% 5-fluorouracil eye drops as primary treatment for ocular surface squamous neoplasia: Long-term follow-up study	5
Cicatricial entropion in eyes with lid margin mucous membrane grafting	5
Editorial Board	5
Pipeline: Pricing for drugs treating dry eye disease	5
Gene expression signatures in conjunctival fornix aspirates of patients with dry eye disease associated with Meibomian gland dysfunction. A proof-of-concept study	5
Pipeline: Pharmacotherapy of dry eye disease in vertebrates	5
Seeing the unseen: Use of a modified OSDI questionnaire to accurately detect chronic ocular GVHD in a hematology clinic	5
Short chain fatty acids inhibit corneal inflammatory responses to TLR ligands via the ocular G-protein coupled receptor 43	5
Transitory alkali exposure on meibomian gland orifices induces meibomian gland dysfunction	5
Matrix glycosaminoglycans and proteoglycans in human cornea organoids and similarities with fetal corneal stages	5