OOIR: Observatory of International Research

Papers

(The TQCC of Ocular Surface is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Effects of Panretinal photocoagulation on the ocular surface and tear film	131
Development and validation of a method to generate phenol red thread tests	83
Editorial Board	70
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–21	68
Endogenous TSG-6 modulates corneal inflammation following chemical injury	58
Atypical microbial keratitis	52
Monkeypox and ocular implications in humans	50
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments	50
Dry eye disease and proteomics	48
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia	45
Editorial Board	44
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease	41
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome	41
A prospective self-controlled study on the alterations of the ocular surface and conjunctival transcriptomic profile associated with prolonged exposure to video display terminals	40
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model	39
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study	38
Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia	38
Effects of age on lacrimal gland bioactive lipids	36
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis	36
Corneal gene therapy: Structural and mechanistic understanding	35
Readership awareness series – Paper 10: Open Access Publishing	34
Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test	34
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician	33
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction	32
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders	32

Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial	32
Impact of digital screen use and lifestyle factors on dry eye disease in the paediatric population	31
TFOS Lifestyle: Impact of nutrition on the ocular surface	30
A practical framework for telemedicine in dry eye disease	30
Investigating the diagnostic utility of non-invasive tear film stability and breakup parameters: A prospective diagnostic accuracy study	29
Cyclosporine A 1mg/ml in pediatric blepharokeratoconjunctivitis: Case series of 145 children and young people	29
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures	29
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies	28
Topical low-dose heparin in ocular Stevens Johnson Syndrome and associated molecular correlations: A randomized controlled pilot study	28
Limiting plastic waste in dry eye practice for environmental sustainability	28
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite	27
Reconsidering the pathogenesis of chalazion	26
The pattern of the inferocentral whorl region of the corneal subbasal nerve plexus is altered with age	26
TFOS: Unique challenges and unmet needs for the management of ocular surface diseases throughout the world	24
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface	23
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction	23
Subconjunctival triamcinolone injection for infectious necrotizing scleritis	22
Keratoneuropathy	22
Trustworthy research presentations	22
Effect of cosmetics on the measurement of the tear lipid layer thickness by LipiView®	22
Exposure keratopathy in patients undergoing invasive ventilation: Prevalence, severity, and the role of surface lubrication	21
Expert consensus on pediatric dry eye: Insights from a European Delphi study	21
Compounded medications for ocular surface disease	21
Evaluating the clinical translational relevance of animal models for limbal stem cell deficiency: A systematic review	21
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study	20
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing	20
Host-microbe interactions in cornea	20
Redefining ocular drug delivery	20
Readership awareness series – Paper 3: Paper mills	20
Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy	20
Label-free quantitative imaging of conjunctival goblet cells	19
Insights into the clinical development of regenerative medical products through a comparison of three cell-based products recently approved for limbal stem cell deficiency	19
Clinical study of laminar resorption: Part 2- outcomes, review and proposal for classification	19
1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface	19
Relationship between screen time and dry eye symptoms in pediatric population during the COVID-19 pandemic	18
The evolution of the modified osteo-odonto-keratoprosthesis, its reliability, and long-term visual rehabilitation prognosis: An analytical review	18
Readership awareness series - Paper 6: How to write a good peer review report?	18
Re: Significant errors in the paper by Ballesteros-Sánchez A, Rocha-de-Lossada C and Sánchez-González J. Efficacy of eyelid warming devices as first-step treatment in meibomian gland dysfunction: A sy	17
Transglutaminase-2 is critical for corneal epithelial barrier function via positive regulation of Claudin-1	17
A novel artificial intelligence model for diagnosing Acanthamoeba keratitis through confocal microscopy	17
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye	17
Visual outcomes of children undergoing penetrating keratoplasty in the US	17
Conjunctival vessel density analysis as a marker of inflammation in dry eye disease	17
Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy	17
Morphological characteristics of Meibomian Glands and their Influence on Dry Eye disease in contact lens wearers	17
Intralesional triamcinolone injection as an adjuvant therapy for refractory cicatrizing conjunctivitis	17
Non-invasive high-contrast imaging of conjunctival goblet cells for the precision diagnosis of ocular surface diseases	16
High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells	16
Identifying patient-valued outcomes for use in early phase trials of ocular surface disease interventions	16
Optimising the method for isolating ocular surface microRNA using impression cytology	16

Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond	16
Evaluation of ocular neuropathic pain	15
Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining	15
Smad4 deficiency ameliorates the progressive corneal stroma thinning caused by the loss of Tbr1	15
Use of a transgenic mouse model for in vivo monitoring of corneal pathologies following Sulfur Mustard Exposure	15
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease	15
Pipeline: Ocular biostatistics: Proper use of proportions	14
Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study	14
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]	14
IL-36α/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress	14
Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions	14
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy	14
Deep Learning-Based Classification of Fungal and Acanthamoeba Keratitis Using Confocal Microscopy	14
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management	14
Readership awareness series – Paper 11: Copyright licensing for scientific publications	14
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity	13
Safety and feasibility of subconjunctival injection of mesenchymal stem cells for acute severe ocular burns: A single-arm study	13
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas	13
Ocular graft-versus-host disease: Experience, incidence, and treatment outcomes at a university-based tertiary care ophthalmology center	13
The effect of botulinum neurotoxin A injections on meibomian glands and dry eye	13
Modified technique for sutureless amniotic membrane transplantation in acute Stevens-Johnson syndrome using fibrin sealant	13
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice	13
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence	13
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study	12
Readership awareness series - Paper 1: Ghost authorship	12
Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity	12
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model	12
Preservatives and ocular surface disease: A review	12
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)	12
Pipeline: US FDA efficacy requirements for treatment of ocular surface disease: Drugs vs. medical devices	12
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy	12
Pipeline: Therapeutics – Two views of off-label use	12
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/3	12
Hyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium	12
Tear metabolomics highlights new potential biomarkers for differentiating between Sjögren's syndrome and other causes of dry eye	11
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”	11
Endoplasmic reticulum stress contributes to the development of ocular graft-vs-host disease in the eyelids and the ocular surface	11
Biological tissues and components, and synthetic substrates for conjunctival cell transplantation	11
Editorial Board	11
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation	11
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation	11
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells	11
Secreted Ly-6/uPAR-related protein-1 (SLURP1) is a pro-differentiation factor that stalls G1-S transition during corneal epithelial cell cycle progression	11
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model	11
Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function	11