OOIR: Observatory of International Research

Papers

(The TQCC of Ocular Surface is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)

Article	Citations
Effects of Panretinal photocoagulation on the ocular surface and tear film	151
Development and validation of a method to generate phenol red thread tests	127
Editorial Board	83
Corrigendum to “New insights into lacrimal gland anatomy using 7T MRI and electron microscopy: Relevance for lacrimal gland targeted therapies and bioengineering” [Ocul. Surf. 30 (October 2023) 204–21	79
Molecular identity of human limbal heterogeneity involved in corneal homeostasis and privilege	66
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments	65
Endogenous TSG-6 modulates corneal inflammation following chemical injury	64
Long term study of topical interferon α-2b eye drops as primary treatment of ocular surface squamous neoplasia	61
Relationship between unhealthy sleep status and dry eye symptoms in a Japanese population: The JPHC-NEXT study	56
Atypical microbial keratitis	51
Chemical and thermal ocular burns in the United States: An IRIS registry analysis	48
Monkeypox and ocular implications in humans	48
Dry eye disease and proteomics	45
Editorial Board	44
Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test	43
The clinical outcomes of minor salivary gland transplantation for severe dry eye disease secondary to chronic Stevens-Johnson syndrome	41
Epidemiology and risk factors for the development of cicatrizing conjunctivitis in chronic ocular graft-versus-host disease	40
Readership awareness series – Paper 10: Open Access Publishing	39
A prospective self-controlled study on the alterations of the ocular surface and conjunctival transcriptomic profile associated with prolonged exposure to video display terminals	38
Organotypic culture model of mouse meibomian gland as a screening platform for risk factors related to meibomian gland dysfunction	38
Impact of digital screen use and lifestyle factors on dry eye disease in the paediatric population	37
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model	37
Herpes simplex virus, varicella-zoster virus and cytomegalovirus keratitis: Facts for the clinician	37
Diagnostic performance and optimal cut-off values for tear film lipid layer grading and thickness in dry eye disease: An investigator-masked, randomised crossover study	36
Chronic inflammation as a proposed risk factor for ocular surface squamous neoplasia	35

Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders	34
Allogeneic mesenchymal stem cell therapy for dry eye disease in patients with Sjögren's syndrome: A randomized clinical trial	34
New disposable esthesiometer (KeraSenseⓇ) to improve diagnosis and management of neurotrophic keratitis	34
Corneal gene therapy: Structural and mechanistic understanding	34
Effects of age on lacrimal gland bioactive lipids	33
Cyclosporine A 1mg/ml in pediatric blepharokeratoconjunctivitis: Case series of 145 children and young people	33
Profile of tear lipid mediator as a biomarker of inflammation for meibomian gland dysfunction and ocular surface diseases: Standard operating procedures	32
Investigating the diagnostic utility of non-invasive tear film stability and breakup parameters: A prospective diagnostic accuracy study	32
Toxicity and efficacy of type I interferons on the ocular surface: in vitro, animal, and clinical studies	32
TFOS: Unique challenges and unmet needs for the management of ocular surface diseases throughout the world	31
The pattern of the inferocentral whorl region of the corneal subbasal nerve plexus is altered with age	31
TFOS Lifestyle: Impact of nutrition on the ocular surface	30
Topical low-dose heparin in ocular Stevens Johnson Syndrome and associated molecular correlations: A randomized controlled pilot study	30
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface	29
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction	29
A practical framework for telemedicine in dry eye disease	29
Limiting plastic waste in dry eye practice for environmental sustainability	28
5-Fluorouracil in primary, impending recurrent and recurrent pterygium: Systematic review of the efficacy and safety of a surgical adjuvant and intralesional antimetabolite	28
Subconjunctival triamcinolone injection for infectious necrotizing scleritis	28
Reconsidering the pathogenesis of chalazion	28
Trustworthy research presentations	27
Effect of cosmetics on the measurement of the tear lipid layer thickness by LipiView®	27
Readership awareness series – Paper 3: Paper mills	26
Meibomian gland dysfunction is suppressed via selective inhibition of immune responses by topical LFA-1/ICAM antagonism with lifitegrast in the allergic eye disease (AED) model	26
Keratoneuropathy	26
Exposure keratopathy in patients undergoing invasive ventilation: Prevalence, severity, and the role of surface lubrication	24
Compounded medications for ocular surface disease	23
Expert consensus on pediatric dry eye: Insights from a European Delphi study	22
Lacrimal gland regeneration: The unmet challenges and promise for dry eye therapy	22
Insights into the clinical development of regenerative medical products through a comparison of three cell-based products recently approved for limbal stem cell deficiency	22
Relationship between screen time and dry eye symptoms in pediatric population during the COVID-19 pandemic	21
Evaluating the clinical translational relevance of animal models for limbal stem cell deficiency: A systematic review	20
Corneal nerve regeneration is affected by scar location in herpes simplex keratitis: A longitudinal in vivo confocal microscopy study	20
Rational design and synthesis of lumican stapled peptides for promoting corneal wound healing	20
Neuronal-epithelial cell alignment: A determinant of health and disease status of the cornea	20
1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface	20
Redefining ocular drug delivery	20
Clinical study of laminar resorption: Part 2- outcomes, review and proposal for classification	20
Label-free quantitative imaging of conjunctival goblet cells	20
Host-microbe interactions in cornea	20
Ocular pain in ocular graft-versus-host disease patients with neurotrophic keratopathy	19
Intralesional triamcinolone injection as an adjuvant therapy for refractory cicatrizing conjunctivitis	19
Ciliogenesis and autophagy are coordinately regulated by EphA2 in the cornea to maintain proper epithelial architecture	19
Readership awareness series - Paper 6: How to write a good peer review report?	19
Conjunctival vessel density analysis as a marker of inflammation in dry eye disease	19
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye	19
Re: Significant errors in the paper by Ballesteros-Sánchez A, Rocha-de-Lossada C and Sánchez-González J. Efficacy of eyelid warming devices as first-step treatment in meibomian gland dysfunction: A sy	19
A novel artificial intelligence model for diagnosing Acanthamoeba keratitis through confocal microscopy	19
The evolution of the modified osteo-odonto-keratoprosthesis, its reliability, and long-term visual rehabilitation prognosis: An analytical review	19
Relationships between activated dendritic cells and dry eye symptoms and signs	18

Morphological characteristics of Meibomian Glands and their Influence on Dry Eye disease in contact lens wearers	18
Transglutaminase-2 is critical for corneal epithelial barrier function via positive regulation of Claudin-1	17
Visual outcomes of children undergoing penetrating keratoplasty in the US	17
High expression of SARS-CoV2 viral entry-related proteins in human limbal stem cells	17
Use of a transgenic mouse model for in vivo monitoring of corneal pathologies following Sulfur Mustard Exposure	17
Drug induced cicatrizing conjunctivitis: A case series with review of etiopathogenesis, diagnosis and management	17
Optimising the method for isolating ocular surface microRNA using impression cytology	17
Non-invasive high-contrast imaging of conjunctival goblet cells for the precision diagnosis of ocular surface diseases	17
Phenotypic characterization of patients developing chronic dry eye and pain after refractive surgery: A cross-sectional study	17
Report on the 2021 Aniridia North America symposium on PAX6, aniridia, and beyond	17
Corrigendum to “Models for Meibomian gland dysfunction: In vivo and in vitro”. Review article, The Ocular Surface 32 (2024) 154–165.	17
Identifying patient-valued outcomes for use in early phase trials of ocular surface disease interventions	16
The role of nitric oxide in ocular surface physiology and pathophysiology	16
Optimising the method for visualising mouse meibomian gland using eyelid whole-mount lipid staining	16
Evaluation of ocular neuropathic pain	15
IL-36α/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress	15
Autologous serum tears improve corneal nerve density and sensitivity in patients with ocular graft-versus-host disease-associated dry eye disease	15
Pipeline: Ocular biostatistics: Proper use of proportions	15
Smad4 deficiency ameliorates the progressive corneal stroma thinning caused by the loss of Tbr1	15
Readership awareness series - Paper 1: Ghost authorship	15
BMAL1 deficiency provokes dry mouth and eyes by down-regulating ITPR2/3	14
Corrigendum to “TFOS lifestyle: Impact of lifestyle challenges on the ocular surface” [Ocul Surf 28 (2023) 262–303]	14
Modified technique for sutureless amniotic membrane transplantation in acute Stevens-Johnson syndrome using fibrin sealant	14
Anterior segment optical coherence tomography angiography in the assessment of ocular surface lesions	14
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas	14
Readership awareness series – Paper 11: Copyright licensing for scientific publications	14
Safety and feasibility of subconjunctival injection of mesenchymal stem cells for acute severe ocular burns: A single-arm study	14
Impact of particulate matter and air pollution on ocular surface disease: A systematic review of preclinical and clinical evidence	13
Hyperosmotic stress-induced NLRP3 inflammasome activation via the mechanosensitive PIEZO1 channel in dry eye corneal epithelium	13
Preservatives and ocular surface disease: A review	13
Ocular graft-versus-host disease: Experience, incidence, and treatment outcomes at a university-based tertiary care ophthalmology center	13
The effect of botulinum neurotoxin A injections on meibomian glands and dry eye	13
A randomized, vehicle-controlled, Phase 2b study of two concentrations of the TRPM8 receptor agonist AR-15512 in the treatment of dry eye disease (COMET-1)	13
The relationship between alcohol consumption and dry eye	13
Essential roles of sensory nerve in maintenance of cornea-phenotype in mice	13
Ocular surface squamous neoplasia: Update on genetics, epigenetics and opportunities for targeted therapy	13
Editorial Board	13
Benzalkonium chloride, a common ophthalmic preservative, compromises rat corneal cold sensitive nerve activity	13
Tetraspanin CD9-derived peptides inhibit Pseudomonas aeruginosa corneal infection and aid in wound healing of corneal epithelial cells	12
Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study	12
Biological tissues and components, and synthetic substrates for conjunctival cell transplantation	12
Tear metabolomics highlights new potential biomarkers for differentiating between Sjögren's syndrome and other causes of dry eye	12
Pipeline: US FDA efficacy requirements for treatment of ocular surface disease: Drugs vs. medical devices	12
Pipeline: Therapeutics – Two views of off-label use	12
In vivo confocal microscopic study of corneal innervation in Sjögren's Syndrome with or without small fiber neuropathy	12
Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model	12
Development and optimization of an ex vivo model of corneal epithelium damage with 1-heptanol: Investigating the influence of donor clinical parameters and MSC-sEV treatment on healing capacity	12
Editorial Board	12
A novel Schirmer strip-based tear matrix metalloproteinase measurement in dry eye evaluation	11
Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair	11
Secreted Ly-6/uPAR-related protein-1 (SLURP1) is a pro-differentiation factor that stalls G1-S transition during corneal epithelial cell cycle progression	11
Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation	11
Synthetic high-density lipoprotein nanoparticles: Good things in small packages	11
Readership awareness series – Paper 7: An overview of impact factor and other scientometrics	11
Mechanoreceptor Piezo1 channel-mediated interleukin expression in conjunctival epithelial cells: Linking mechanical stress to ocular inflammation	11
Pard3 promotes corneal epithelial stratification and homeostasis by regulating apical-basal polarity, cytoskeletal organization and tight junction-mediated barrier function	11
Restoration of corneal epithelial barrier function: A possible target for corneal neovascularization	11
Adipose-derived mesenchymal stromal cells: A study on safety and efficacy in ocular inflammation	11
Immune signaling in rosacea	11
Letter to the editor regarding “TFOS Lifestyle: Impact of the digital environment on the ocular surface”	11
Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse model	11
Endoplasmic reticulum stress contributes to the development of ocular graft-vs-host disease in the eyelids and the ocular surface	11
Safety and efficacy of UV application for superficial infections in humans: A systematic review and meta-analysis	11