Ocular Surface

Papers
(The TQCC of Ocular Surface is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection232
The evidence of SARS-CoV-2 infection on ocular surface201
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells107
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface104
Prevalence and risk factors of dry eye in 79,866 participants of the population-based Lifelines cohort study in the Netherlands93
The keratoconus enigma: A review with emphasis on pathogenesis87
Prevalence of SARS-CoV-2 in human post-mortem ocular tissues86
Corneal stromal wound healing: Major regulators and therapeutic targets70
Fungal keratitis: A review of clinical presentations, treatment strategies and outcomes62
Assessing the ocular surface microbiome in severe ocular surface diseases58
Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea57
Use of digital displays and ocular surface alterations: A review49
Intense pulsed light treatment in meibomian gland dysfunction: A concise review47
NLRP12- and NLRC4-mediated corneal epithelial pyroptosis is driven by GSDMD cleavage accompanied by IL-33 processing in dry eye47
Ocular surface microbiota in patients with aqueous tear-deficient dry eye46
The physical and mental burden of dry eye disease: A large population-based study investigating the relationship with health-related quality of life and its determinants46
Organoids and organ chips in ophthalmology45
Molecular identity of human limbal heterogeneity involved in corneal homeostasis and privilege44
Pigment epithelium-derived factor (PEDF) plays anti-inflammatory roles in the pathogenesis of dry eye disease42
Demographic and lifestyle risk factors of dry eye disease subtypes: A cross-sectional study42
Long-term outcomes of amniotic membrane treatment in acute Stevens-Johnson syndrome/toxic epidermal necrolysis41
The eye as the discrete but defensible portal of coronavirus infection41
Safety and feasibility of mesenchymal stem cell therapy in patients with aqueous deficient dry eye disease40
New insights into the lacrimal pump40
The relationship between dry eye and sleep quality39
Visualization of microneuromas by using in vivo confocal microscopy: An objective biomarker for the diagnosis of neuropathic corneal pain?39
Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation36
Ageing and the natural history of dry eye disease: A prospective registry-based cross-sectional study34
Impact of the COVID-19 pandemic on eye strain and dry eye symptoms33
Decellularized porcine cornea-derived hydrogels for the regeneration of epithelium and stroma in focal corneal defects32
Ocular manifestations of anti-neoplastic immune checkpoint inhibitor-associated Stevens-Johnson syndrome/toxic epidermal necrolysis in cancer patients32
The ocular surface immune system through the eyes of aging32
Ocular surface disease associated with dupilumab treatment for atopic diseases31
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions31
Correlation of corneal immune cell changes with clinical severity in dry eye disease: An in vivo confocal microscopy study31
The molecular basis of neurotrophic keratopathy: Diagnostic and therapeutic implications. A review31
Systemic risk factors of dry eye disease subtypes: A New Zealand cross-sectional study29
TFOS Lifestyle Report: Impact of environmental conditions on the ocular surface29
Alterations in corneal nerves in different subtypes of dry eye disease: An in vivo confocal microscopy study29
Latest evidences on meibomian gland dysfunction diagnosis and management28
Diagnostic armamentarium of infectious keratitis: A comprehensive review27
Interactions of polar lipids with cholesteryl ester multilayers elucidate tear film lipid layer structure27
Management of corneal complications in vernal keratoconjunctivitis: A review27
A phase II randomized trial to evaluate the long-term (12-week) efficacy and safety of OC-01 (varenicline solution) nasal spray for dry eye disease: The MYSTIC study27
Epithelium-derived IL-33 activates mast cells to initiate neutrophil recruitment following corneal injury27
Impact of aging on the pathophysiology of dry eye disease: A systematic review and meta-analysis27
The role of Th17 immunity in chronic ocular surface disorders27
Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease27
Eicosapentaenoic acid (EPA) activates PPARγ signaling leading to cell cycle exit, lipid accumulation, and autophagy in human meibomian gland epithelial cells (hMGEC)26
Relationships between activated dendritic cells and dry eye symptoms and signs26
Supramolecular host-guest hyaluronic acid hydrogels enhance corneal wound healing through dynamic spatiotemporal effects26
The epidemiology of infectious keratitis25
Developing evidence-based guidance for the treatment of dry eye disease with artificial tear supplements: A six-month multicentre, double-masked randomised controlled trial25
Giant papillary conjunctivitis: A review25
TFOS Lifestyle: Impact of the digital environment on the ocular surface25
Altered ocular surface immune cell profile in patients with dry eye disease25
Melanocytes as emerging key players in niche regulation of limbal epithelial stem cells24
Dry anophthalmic socket syndrome – Standardized clinical evaluation of symptoms and signs24
Ocular redness – I: Etiology, pathogenesis, and assessment of conjunctival hyperemia24
Ocular surface diabetic disease: A neurogenic condition?24
Dry eye disease in children and adolescents in India24
Artificial intelligence in dry eye disease23
The vision-related burden of dry eye23
A systematic review of cellular therapies for the treatment of limbal stem cell deficiency affecting one or both eyes23
The use of in vivo confocal microscopy in fungal keratitis – Progress and challenges22
Abnormal neovascular and proliferative conjunctival phenotype in limbal stem cell deficiency is associated with altered microRNA and gene expression modulated by PAX6 mutational status in congenital a22
Activation of ocular surface mast cells promotes corneal neovascularization22
Meibomian gland dysfunction is the primary determinant of dry eye symptoms: Analysis of 2346 patients22
Comparison of clinical characteristics of post-refractive surgery-related and post-herpetic neuropathic corneal pain22
Transcriptomic profiling of human corneal epithelial cells exposed to airborne fine particulate matter (PM2.5)22
In-situ porcine corneal matrix hydrogel as ocular surface bandage21
Low-dose naltrexone is effective and well-tolerated for modulating symptoms in patients with neuropathic corneal pain21
Interleukin-4 stimulates lipogenesis in meibocytes by activating the STAT6/PPARγ signaling pathway21
Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis21
Epidemiology, economic and humanistic burdens of Ocular Surface Chemical Injury: A narrative review21
A randomized, sham-controlled trial of intraductal meibomian gland probing with or without topical antibiotic/steroid for obstructive meibomian gland dysfunction21
Lid margin keratinization in Stevens-Johnson syndrome: Review of pathophysiology and histopathology21
Corneal neurotization for neurotrophic keratopathy: Review of surgical techniques and outcomes21
Enhanced closed eye neutrophil degranulation in dry eye disease20
The utility of anterior segment optical coherence tomography angiography for the assessment of limbal stem cell deficiency20
Pigment Epithelium-derived Factor secreted by corneal epithelial cells regulates dendritic cell maturation in dry eye disease20
SARS-CoV-2 receptor ACE2 is expressed in human conjunctival tissue, especially in diseased conjunctival tissue20
Role of optical coherence tomography angiography in the characterization of vascular network patterns of ocular surface squamous neoplasia20
Tissue engineered corneal epithelium derived from clinical-grade human embryonic stem cells20
Repurposing medications20
DryEyeRhythm: A reliable and valid smartphone application for the diagnosis assistance of dry eye20
Membrane-associated mucins of the human ocular surface in health and disease20
Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients19
Efficacy and tolerability of nortriptyline in the management of neuropathic corneal pain19
Matrix metalloproteinase 9 positivity predicts long term decreased tear production19
SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response19
TFOS Lifestyle: Impact of lifestyle challenges on the ocular surface19
Decellularized porcine conjunctiva as an alternative substrate for tissue-engineered epithelialized conjunctiva19
Type 1 diabetes mellitus impairs diurnal oscillations in murine extraorbital lacrimal glands18
Alteration in meibum lipid composition and subjective symptoms due to aging and meibomian gland dysfunction18
Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach18
Topical glaucoma medications – Clinical implications for the ocular surface18
Dysfunction of the limbal epithelial stem cell niche in aniridia-associated keratopathy18
The role of nitric oxide in ocular surface physiology and pathophysiology18
Relationship between screen time and dry eye symptoms in pediatric population during the COVID-19 pandemic18
Association of dry eye disease and sun exposure in geographically diverse adult (≥40 years) populations of India: The SEED (sun exposure, environment and dry eye disease) study - Second report of the 17
TFOS lifestyle: Impact of societal challenges on the ocular surface17
Clinical practice patterns in the management of dry eye disease: A TFOS international survey17
New insight into lacrimal gland function: Role of the duct epithelium in tear secretion17
Corneal lymphangiogenesis in dry eye disease is regulated by substance P/neurokinin-1 receptor system through controlling expression of vascular endothelial growth factor receptor 316
The role of meibography in ocular surface diagnostics: A review16
Retroprosthetic membrane: A complication of keratoprosthesis with broad consequences16
Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids in meibomian gland dysfunction16
TFOS Lifestyle: Impact of contact lenses on the ocular surface15
TFOS Lifestyle: Impact of nutrition on the ocular surface15
Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders15
IL-36α/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress15
Ocular surface disease in thyroid eye disease: A narrative review15
Safety and efficacy of UV application for superficial infections in humans: A systematic review and meta-analysis15
Automated quantification of meibomian gland dropout in infrared meibography using deep learning15
TFOS Lifestyle: Impact of elective medications and procedures on the ocular surface15
TFOS Lifestyle: Impact of cosmetics on the ocular surface15
The link between Keratoconus and posterior segment parameters: An updated, comprehensive review15
Relationship between unhealthy sleep status and dry eye symptoms in a Japanese population: The JPHC-NEXT study14
Light cycle phase advance as a model for jet lag reprograms the circadian rhythms of murine extraorbital lacrimal glands14
Long-term outcomes of cultivated cell sheet transplantation for treating total limbal stem cell deficiency14
The relationship between alcohol consumption and dry eye14
The potential of lipid mediator networks as ocular surface therapeutics and biomarkers14
A reliable animal model of corneal stromal opacity: Development and validation using in vivo imaging14
Efficacy of cyanoacrylate tissue adhesive in the management of corneal thinning and perforation due to microbial keratitis14
Assessment of response to multimodal management of neurotrophic corneal disease14
Epigenetic regulation of anterior segment diseases and potential therapeutics14
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