OOIR: Observatory of International Research

Papers

(The median citation count of Clinical Proteomics is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy	187
Distinct proteomic profiles of clinical isolates show diversity of Pseudomonas aeruginosa colistin-resistance	71
Recent progress in mass spectrometry-based urinary proteomics	53
From blood drops to biomarkers: a scoping review of microsampling in mass spectrometry-based proteomics	41
Changes of serum IgG glycosylation patterns in rheumatoid arthritis	31
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka	30
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue	29
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies	28
Correction: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	27
Quantification of putative ovarian cancer serum protein biomarkers using a multiplexed targeted mass spectrometry assay	26
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds	25
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities	24
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers	23
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue	22
Proteomic alteration of endometrial tissues during secretion in polycystic ovary syndrome may affect endometrial receptivity	22
Proteomic profiles screening identified novel exosomal protein biomarkers for diagnosis of lung cancer	18
Elevated level of multibranched complex glycan reveals an allergic tolerance status	17
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study	17
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach	15
An ALS assembly modulator signature in peripheral blood mononuclear cells: implications for ALS pathophysiology, therapeutics, and diagnostics	14
Integrated serum proteomics and metabolomics reveal an INR-associated multi-omics signature in hepatocellular carcinoma	14
Correction: A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples	13
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19	13
Plasma exosome proteomics reveals upregulation of CILP-1 in concave side of paraspinal muscle in adolescent idiopathic scoliosis	13
Discovery of novel glioma serum biomarkers by proximity extension assay	13

Quantitative site-specific N-glycosylation analysis reveals IgG glyco-signatures for pancreatic cancer diagnosis	13
Integrating human plasma proteomes with genome-wide association data implicates novel proteins and drug targets for rheumatoid arthritis	12
Plasma proteomic profiling reveals distinct protein signatures associated with hepatocellular carcinoma in chronic hepatitis B infection	12
Neat plasma proteomics: getting the best out of the worst	12
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas	12
Plasma proteomics in pediatric patients with sepsis– hopes and challenges	12
Proteomic analyses reveal cystatin c is a promising biomarker for evaluation of systemic lupus erythematosus	12
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology	12
Many kinds of oxidized proteins are present more in the urine of the elderly	11
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort	11
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection	11
Longitudinal serum proteomics identifies inflammatory and metabolic pathways in hypertensive nephrosclerosis progression	11
Plasma proteomics of extracellular vesicles identifies key proteins correlating to postoperative atrial fibrillation after coronary artery bypass surgery	11
Comparative evaluation of analytical methods for CSF proteomics	10
Label-free LC–MS/MS proteomics analyses reveal proteomic changes in oxidative stress and the SOD antioxidant strategy in TM cells	10
Causal effects and mediation pathways of circulating plasma proteins on osteoporosis: a two-sample and two-step Mendelian randomization study	10
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics	10
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	10
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets	10
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides	10
Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach	9
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response	9
Proteome profiling of cerebrospinal fluid-derived extracellular vesicles reveals potential biomarkers for drug-resistant epilepsy	9
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers	9
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex	9
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors	9
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers	9
Clinic-first sepsis recognition in the ICU: a proteomics-guided, parsimonious model with independent validation	9
Integrating functional proteomics and next generation sequencing reveals potential therapeutic targets for Taiwanese breast cancer	9
ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach	9
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study	9
Integrating multimodal data to predict the progression of hormone-sensitive prostate cancer	9
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion	9
Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling	8
Calcium-related genes predict prognosis, immune characteristics, and response to immunotherapy in LUAD patients	8
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection	8
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization	8
SPOT: spatial proteomics through on-site tissue-protein-labeling	8
Novel plasma protein biomarkers from critically ill sepsis patients	8
Human tear film protein sampling using soft contact lenses	8
Identification of adrenocorticotropic hormone–specific therapeutic biomarkers in infantile epileptic spasm syndrome using data-independent acquisition mass spectrometry	8
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer	8
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways	8
Evaluation of the relationship between inflammation and typical chest pain in ST-elevation myocardial infarction	7
Urinary exosomal RAB11A serves as a novel non-invasive biomarker for diagnosis, treatment response monitoring, and prognosis in small cell lung cancer	7
Proximity extension assay-based serum proteomic profiling identifies shared protein signatures in hypermobile Ehlers–Danlos syndrome and hypermobility spectrum disorders	7
Assessing the consistency of mass spectrometry, a clinical-laboratory model, and immunohistochemistry in amyloid subtyping: a Brazilian experience	7
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls	7
Closing the gaps in patient management of dyslipidemia: stepping into cardiovascular precision diagnostics with apolipoprotein profiling	7
New mechanisms and biomarkers of lymph node metastasis in cervical cancer: reflections from plasma proteomics	7

Correction to: A novel non‑invasive method allowing for discovery of pathologically relevant proteins from small airways	7
Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation	7
An LC–MS-based designated comparison method with similar performance to the Lp(a) reference measurement procedure to guide molar Lp(a) standardization	7
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers	7
Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis	7
Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus	7
Identification of serum proteins associated with response of triple-negative breast cancer to neoadjuvant chemotherapy: preliminary results from the INSTIGO trial	7
Spatial proteomics to discover aging-associated alterations in the renal tubulointerstitium	7
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories	6
Frontiers in plasma proteome profiling platforms: innovations and applications	6
Redefining serological diagnostics with immunoaffinity proteomics	6
Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins	6
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals	6
Absolute quantitation of human wild-type DNAI1 protein in lung tissue using a nanoLC-PRM-MS-based targeted proteomics approach coupled with immunoprecipitation	6
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies	6
Identification of serum N-glycans signatures in three major gastrointestinal cancers by high-throughput N-glycome profiling	6
Using established biorepositories for emerging research questions: a feasibility study	6
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry	6
Spatial top-down proteomics for the functional characterization of human kidney	6
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line	6
Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry	6
Application of urine proteomics in the diagnosis and treatment effectiveness monitoring of early-stage Mycosis Fungoides	6
Correction to: Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources	5
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics	5
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips	5
Comparative proteomic analysis of glomerular proteins in IgA nephropathy and IgA vasculitis with nephritis	5
Unveiling the protein landscape for early detection of colorectal precancerous lesions	5
Proteomic profiles in the aqueous following anti-vegf therapy in treatment naïve neovascular age-related macular degeneration	5
Advances in mucopolysaccharidosis research: the impact of mass spectrometry-based approaches	5
Exploring the novel duo of Reticulocalbin, and Sideroflexin as future biomarker candidates for Exacerbated Chronic Obstructive Pulmonary Disease	5
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases	5
Identification of novel proteomic biomarkers for hypertension: a targeted approach for precision medicine	5
Proteomic profile and predictive markers of outcome in patients with subarachnoid hemorrhage	5
Optimized data-independent acquisition approach for proteomic analysis at single-cell level	5
Correction: Unveiling the protein landscape for early detection of colorectal precancerous lesions	5
Identification of SARS-CoV-2 biomarkers in saliva by transcriptomic and proteomics analysis	5
Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma	5
Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?	5
Differentiation between descending thoracic aortic diseases using machine learning and plasma proteomic signatures	4
Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS	4
Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF)	4
Protein corona proteomics characterizes low-abundance plasma protein signatures and highlights ferroptosis-associated signals in uremic hemodialysis patients	4
Change of histone H3 lysine 14 acetylation stoichiometry in human monocyte derived macrophages as determined by MS-based absolute targeted quantitative proteomic approach: HIV infection and methamphet	4
Maternal serum CFHR4 protein as a potential non-invasive marker of ventricular septal defects in offspring: evidence from a comparative proteomics study	4
Label-free quantitative proteomic analysis of serum exosomes from patients of renal anemia: The Good and the Bad of Roxadustat	4
TMT-based proteomic analysis of radiation lung injury in rats	4
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cell	4
Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates	4
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers	4
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders	4
Associations of plasma protein levels with risk of colorectal cancer: a proteome-wide Mendelian randomization study	4
A proteomic profile of the healthy human placenta	4
Proteomics of human duodenum in pre-diabetes and type 2 diabetes reveals potential novel therapeutic targets for aetiology and therapeutics	4
Combined urine proteomics and metabolomics analysis for the diagnosis of pulmonary tuberculosis	4
Identification and verification of plasma protein biomarkers that accurately identify an ectopic pregnancy	4
The effect of storage time and temperature on the proteomic analysis of FFPE tissue sections	4
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics	4
Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals	4