OOIR: Observatory of International Research

Papers

(The median citation count of Clinical Proteomics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy	73
Changes of serum IgG glycosylation patterns in rheumatoid arthritis	40
From blood drops to biomarkers: a scoping review of microsampling in mass spectrometry-based proteomics	28
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue	24
Recent progress in mass spectrometry-based urinary proteomics	24
Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model	23
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds	22
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases	22
Correction: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	20
Quantification of putative ovarian cancer serum protein biomarkers using a multiplexed targeted mass spectrometry assay	20
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies	20
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka	20
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities	18
Proteomic alteration of endometrial tissues during secretion in polycystic ovary syndrome may affect endometrial receptivity	18
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers	17
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue	17
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study	16
Quantitative site-specific N-glycosylation analysis reveals IgG glyco-signatures for pancreatic cancer diagnosis	15
Proteomic profiles screening identified novel exosomal protein biomarkers for diagnosis of lung cancer	15
An ALS assembly modulator signature in peripheral blood mononuclear cells: implications for ALS pathophysiology, therapeutics, and diagnostics	14
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach	14
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19	13
Discovery of novel glioma serum biomarkers by proximity extension assay	12
Correction: A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples	12
Elevated level of multibranched complex glycan reveals an allergic tolerance status	12

Plasma proteomics in pediatric patients with sepsis– hopes and challenges	12
Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach	11
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology	11
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort	11
Neat plasma proteomics: getting the best out of the worst	11
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas	9
Longitudinal serum proteomics identifies inflammatory and metabolic pathways in hypertensive nephrosclerosis progression	9
Association between cardiovascular disease- and inflammation-related serum biomarkers and poor lung function in elderly	9
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides	9
Proteomic analyses reveal cystatin c is a promising biomarker for evaluation of systemic lupus erythematosus	9
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response	8
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection	8
Label-free LC–MS/MS proteomics analyses reveal proteomic changes in oxidative stress and the SOD antioxidant strategy in TM cells	8
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics	8
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets	8
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers	8
Many kinds of oxidized proteins are present more in the urine of the elderly	8
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study	8
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization	7
Integrating functional proteomics and next generation sequencing reveals potential therapeutic targets for Taiwanese breast cancer	7
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex	7
Integrating multimodal data to predict the progression of hormone-sensitive prostate cancer	7
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion	7
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	7
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors	7
A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples	7
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers	7
Quantitative proteomic analysis of serum-purified exosomes identifies putative pre-eclampsia-associated biomarkers	6
Human tear film protein sampling using soft contact lenses	6
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection	6
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers	6
Novel plasma protein biomarkers from critically ill sepsis patients	6
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer	6
ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach	6
Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation	6
Proteomic profiling of extracellular vesicles derived from human serum for the discovery of biomarkers in Avascular necrosis	6
SPOT: spatial proteomics through on-site tissue-protein-labeling	6
Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling	6
An LC–MS-based designated comparison method with similar performance to the Lp(a) reference measurement procedure to guide molar Lp(a) standardization	5
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls	5
New mechanisms and biomarkers of lymph node metastasis in cervical cancer: reflections from plasma proteomics	5
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways	5
Proteomic analysis identifies subgroups of patients with active systemic lupus erythematosus	5
Identification of serum N-glycans signatures in three major gastrointestinal cancers by high-throughput N-glycome profiling	5
Identification of biomarkers of chronic kidney disease among kidney-derived proteins	5
Closing the gaps in patient management of dyslipidemia: stepping into cardiovascular precision diagnostics with apolipoprotein profiling	5
Spatial top-down proteomics for the functional characterization of human kidney	5
Correction to: A novel non‑invasive method allowing for discovery of pathologically relevant proteins from small airways	5
Absolute quantitation of human wild-type DNAI1 protein in lung tissue using a nanoLC-PRM-MS-based targeted proteomics approach coupled with immunoprecipitation	4
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature	4

Frontiers in plasma proteome profiling platforms: innovations and applications	4
Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry	4
Using established biorepositories for emerging research questions: a feasibility study	4
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry	4
Validation and update of a multivariable prediction model for the identification and management of patients at risk for hepatocellular carcinoma	4
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals	4
Circulating microvesicles and exosomes in small cell lung cancer by quantitative proteomics	4
Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins	4
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories	4
Redefining serological diagnostics with immunoaffinity proteomics	4
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line	4
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies	4
Application of urine proteomics in the diagnosis and treatment effectiveness monitoring of early-stage Mycosis Fungoides	4
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases	3
OmicsOne: associate omics data with phenotypes in one-click	3
TMT-based proteomic analysis of radiation lung injury in rats	3
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips	3
Correction to: Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources	3
Identification of novel proteomic biomarkers for hypertension: a targeted approach for precision medicine	3
Neoplastic cell enrichment of tumor tissues using coring and laser microdissection for proteomic and genomic analyses of pancreatic ductal adenocarcinoma	3
Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS	3
Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants	3
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics	3
Identification of SARS-CoV-2 biomarkers in saliva by transcriptomic and proteomics analysis	3
Proteomic profile and predictive markers of outcome in patients with subarachnoid hemorrhage	3
Combined urine proteomics and metabolomics analysis for the diagnosis of pulmonary tuberculosis	3
Tailored therapeutic decision of rheumatoid arthritis using proteomic strategies: how to start and when to stop?	3
Comparative proteomic analysis of glomerular proteins in IgA nephropathy and IgA vasculitis with nephritis	3
Optimized data-independent acquisition approach for proteomic analysis at single-cell level	3
Exploring the novel duo of Reticulocalbin, and Sideroflexin as future biomarker candidates for Exacerbated Chronic Obstructive Pulmonary Disease	3
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers	2
Differentiation between descending thoracic aortic diseases using machine learning and plasma proteomic signatures	2
The effect of storage time and temperature on the proteomic analysis of FFPE tissue sections	2
Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates	2
Glycoproteomics revealed novel N-glycosylation biomarkers for early diagnosis of lung adenocarcinoma cancers	2
Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets	2
Quantitative proteomics identified circulating biomarkers in lung adenocarcinoma diagnosis	2
Admission glucose, HbA1c levels and inflammatory cytokines in patients with acute ST-elevation myocardial infarction	2
Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan	2
Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals	2
Early detection of breast cancer through the diagnosis of Nipple Aspirate Fluid (NAF)	2
A proteomic profile of the healthy human placenta	2
Change of histone H3 lysine 14 acetylation stoichiometry in human monocyte derived macrophages as determined by MS-based absolute targeted quantitative proteomic approach: HIV infection and methamphet	2
iTRAQ-based quantitative proteomic analysis of thoracic aortas from adult rats born to preeclamptic dams	2
Circulating proteins as predictive and prognostic biomarkers in breast cancer	2
VCAM-1 complements CA-125 in detecting recurrent ovarian cancer	2
Identification of novel proteins in inflammatory bowel disease based on the gut-brain axis: a multi-omics integrated analysis	2
Cord blood platelet-rich plasma: proteomics analysis for ophthalmic applications	2
Label-free quantitative proteomic analysis of serum exosomes from patients of renal anemia: The Good and the Bad of Roxadustat	2
Use of MS-GUIDE for identification of protein biomarkers for risk stratification of patients with prostate cancer	2
Identification and verification of plasma protein biomarkers that accurately identify an ectopic pregnancy	2
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cell	2
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics	2
Serum proteomics of severe fever with thrombocytopenia syndrome patients	2
Identification of ORM1, vWF, SPARC, and PPBP as immune-related proteins involved in immune thrombocytopenia by quantitative LC-MS/MS	2
Serum proteomics unveil characteristic protein diagnostic biomarkers and signaling pathways in patients with esophageal squamous cell carcinoma	2
Analytical validation of a multi-biomarker algorithmic test for prediction of progressive kidney function decline in patients with early-stage kidney disease	2
Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: a case study of an urothelial cancer cohort analyzed in the Galaxy framework	2
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders	2
Maternal serum CFHR4 protein as a potential non-invasive marker of ventricular septal defects in offspring: evidence from a comparative proteomics study	2