Clinical Proteomics

Papers
(The median citation count of Clinical Proteomics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Recent advances in mass spectrometry based clinical proteomics: applications to cancer research166
Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer’s disease52
A comprehensive systematic review of CSF proteins and peptides that define Alzheimer’s disease40
Mass spectrometry-based microbiological testing for blood stream infection39
Laser capture microdissection coupled mass spectrometry (LCM-MS) for spatially resolved analysis of formalin-fixed and stained human lung tissues37
Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources35
CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis26
Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients25
Circulating proteins as predictive and prognostic biomarkers in breast cancer23
Effects of cryopreservation and long-term culture on biological characteristics and proteomic profiles of human umbilical cord-derived mesenchymal stem cells20
The plasma peptides of Alzheimer’s disease19
Proteomic analysis of human synovial fluid reveals potential diagnostic biomarkers for ankylosing spondylitis19
Clinical proteomics for prostate cancer: understanding prostate cancer pathology and protein biomarkers for improved disease management19
Proteomic analysis of decidua in patients with recurrent pregnancy loss (RPL) reveals mitochondrial oxidative stress dysfunction18
Tear proteomic profile in three distinct ocular surface diseases: keratoconus, pterygium, and dry eye related to graft-versus-host disease17
The plasma peptides of sepsis16
Identification of pathogens from native urine samples by MALDI-TOF/TOF tandem mass spectrometry16
A proteomic repertoire of autoantigens identified from the classic autoantibody clinical test substrate HEp-2 cells15
Label-free proteomic analysis of serum exosomes from paroxysmal atrial fibrillation patients15
Urine proteomics identifies biomarkers for diabetic kidney disease at different stages15
Quantitative proteomics-based analyses performed on pre-eclampsia samples in the 2004–2020 period: a systematic review14
Circulating microvesicles and exosomes in small cell lung cancer by quantitative proteomics14
Rational selection of a biomarker panel targeting unmet clinical needs in kidney injury14
Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants13
Secreted protein markers in oral squamous cell carcinoma (OSCC)12
Variable blood processing procedures contribute to plasma proteomic variability12
Human follicular fluid proteome reveals association between overweight status and oocyte maturation abnormality10
Identification of TUBB2A by quantitative proteomic analysis as a novel biomarker for the prediction of distant metastatic breast cancer10
A nomogram based on glycomic biomarkers in serum and clinicopathological characteristics for evaluating the risk of peritoneal metastasis in gastric cancer10
Proteomic and phosphoproteomic measurements enhance ability to predict ex vivo drug response in AML10
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers10
Evaluation of the potential of Pap test fluid and cervical swabs to serve as clinical diagnostic biospecimens for the detection of ovarian cancer by mass spectrometry-based proteomics10
Development of a novel method for the quantification of tyrosine 39 phosphorylated α- and β-synuclein in human cerebrospinal fluid10
A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples10
Quantitative analysis of differentially expressed proteins in psoriasis vulgaris using tandem mass tags and parallel reaction monitoring9
Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan9
Quantitative proteomic analysis of serum-purified exosomes identifies putative pre-eclampsia-associated biomarkers9
Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation9
Mass spectrometry-based proteomics as an emerging tool in clinical laboratories9
Optimized data-independent acquisition approach for proteomic analysis at single-cell level9
Quantitative proteomics analysis of lysine 2-hydroxyisobutyrylation in IgA nephropathy8
Identification of circular RNA BTBD7_hsa_circ_0000563 as a novel biomarker for coronary artery disease and the functional discovery of BTBD7_hsa_circ_0000563 based on peripheral blood mononuclear cell8
Proteomic approaches for characterizing renal cell carcinoma8
A rigorous evaluation of optimal peptide targets for MS-based clinical diagnostics of Coronavirus Disease 2019 (COVID-19)7
A robust multiplex immunoaffinity mass spectrometry assay (PromarkerD) for clinical prediction of diabetic kidney disease7
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature7
Analytical validation of a multi-biomarker algorithmic test for prediction of progressive kidney function decline in patients with early-stage kidney disease7
Subclinical effects of remote ischaemic conditioning in human kidney transplants revealed by quantitative proteomics7
LC-MS/MS based metabolomics and proteomics reveal candidate biomarkers and molecular mechanism of early IgA nephropathy7
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases7
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis6
Discovery of novel glioma serum biomarkers by proximity extension assay6
Circulating proteins associated with allergy development in infants—an exploratory analysis6
Mitochondria and cytochrome components released into the plasma of severe COVID-19 and ICU acute respiratory distress syndrome patients6
Early changes in tear film protein profiles after femtosecond LASIK surgery6
Global proteome profiling of human livers upon ischemia/reperfusion treatment6
Moving translational mass spectrometry imaging towards transparent and reproducible data analyses: a case study of an urothelial cancer cohort analyzed in the Galaxy framework6
Systematic evaluation and optimization of protein extraction parameters in diagnostic FFPE specimens6
O-GlcNAcylation protein disruption by Thiamet G promotes changes on the GBM U87-MG cells secretome molecular signature5
Novel plasma protein biomarkers from critically ill sepsis patients5
Development of robust targeted proteomics assays for cerebrospinal fluid biomarkers in multiple sclerosis5
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls5
Use of MS-GUIDE for identification of protein biomarkers for risk stratification of patients with prostate cancer5
Serum proteomics unveil characteristic protein diagnostic biomarkers and signaling pathways in patients with esophageal squamous cell carcinoma5
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways5
Label-free quantitative proteomic analysis of serum exosomes from patients of renal anemia: The Good and the Bad of Roxadustat5
Quantitative proteomics reveals the effect of Yigu decoction (YGD) on protein expression in bone tissue4
Label-free LC–MS/MS proteomics analyses reveal proteomic changes in oxidative stress and the SOD antioxidant strategy in TM cells4
Association between cardiovascular disease- and inflammation-related serum biomarkers and poor lung function in elderly4
Application of SWATH mass spectrometry in the identification of circulating proteins does not predict future weight gain in early psychosis4
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response4
Uncomplicated Plasmodium vivax malaria: mapping the proteome from circulating platelets4
Determination of temporal reproducibility and variability of cancer biomarkers in serum and EDTA plasma samples using a proximity extension assay4
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study4
A validated analysis pipeline for mass spectrometry-based vitreous proteomics: new insights into proliferative diabetic retinopathy4
Activity-based protein profiling guided identification of urine proteinase 3 activity in subclinical rejection after renal transplantation3
Label-free quantitative proteomics reveals aberrant expression levels of LRG, C9, FN, A1AT and AGP1 in the plasma of patients with colorectal cancer3
Proteomics-based evaluation of the mechanism underlying vascular injury via DNA interstrand crosslinks, glutathione perturbation, mitogen-activated protein kinase, and Wnt and ErbB signaling pathways 3
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion3
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line3
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers3
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry3
Identification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer3
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection3
Redefining serological diagnostics with immunoaffinity proteomics3
The use of proteomics for blood biomarker research in premature infants: a scoping review3
A proteomic profile of the healthy human placenta3
Identification of biomarkers of chronic kidney disease among kidney-derived proteins3
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics3
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy3
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection3
Changes of serum IgG glycosylation patterns in rheumatoid arthritis2
Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach2
Identification of ORM1, vWF, SPARC, and PPBP as immune-related proteins involved in immune thrombocytopenia by quantitative LC-MS/MS2
Proteomic alterations associated with residual disease in neoadjuvant chemotherapy treated ovarian cancer tissues2
Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients2
Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling2
Chloride intracellular channel 4 participate in the protective effect of Ginkgolide B in MPP+ injured MN9D cells: insight from proteomic analysis2
Validation and update of a multivariable prediction model for the identification and management of patients at risk for hepatocellular carcinoma2
Many kinds of oxidized proteins are present more in the urine of the elderly2
Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates2
The associations between red cell distribution width and plasma proteins in a general population2
Integration of protein context improves protein-based COVID-19 patient stratification2
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips2
iTRAQ-based quantitative proteomic analysis of thoracic aortas from adult rats born to preeclamptic dams2
Comparative analysis of differentially abundant proteins quantified by LC–MS/MS between flash frozen and laser microdissected OCT-embedded breast tumor samples2
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies2
Comparative proteomics analysis in different stages of urothelial bladder cancer for identification of potential biomarkers: highlighted role for antioxidant activity2
OmicsOne: associate omics data with phenotypes in one-click2
Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation2
Proteomic alteration of endometrial tissues during secretion in polycystic ovary syndrome may affect endometrial receptivity2
A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors2
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals2
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