Clinical Proteomics

Papers
(The median citation count of Clinical Proteomics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets59
Functional and quantitative evaluation of the 20S proteasome in serum and intracellular in145 moroccan patients with hematologic malignancies33
Glycoproteomics revealed novel N-glycosylation biomarkers for early diagnosis of lung adenocarcinoma cancers26
Development of a predictive model to distinguish prostate cancer from benign prostatic hyperplasia by integrating serum glycoproteomics and clinical variables22
The use of proteomics for blood biomarker research in premature infants: a scoping review21
Comparative proteomic analysis of glomerular proteins in primary and bucillamine-induced membranous nephropathy21
Serum proteomics of severe fever with thrombocytopenia syndrome patients20
Kinase inhibitor pulldown assay (KiP) for clinical proteomics20
Validation and update of a multivariable prediction model for the identification and management of patients at risk for hepatocellular carcinoma20
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection18
Transcriptome profiling and proteomic validation reveals targets of the androgen receptor signaling in the BT-474 breast cancer cell line18
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides17
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders17
Many kinds of oxidized proteins are present more in the urine of the elderly17
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response16
Changes in amino acid concentrations and the gut microbiota composition are implicated in the mucosal healing of ulcerative colitis and can be used as noninvasive diagnostic biomarkers15
The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals14
Proteome analysis of CD5-positive diffuse large B cell lymphoma FFPE tissue reveals downregulation of DDX3X, DNAJB1, and B cell receptor signaling pathway proteins including BTK and Immunoglobulins14
Orthogonal proteomics methods warrant the development of Duchenne muscular dystrophy biomarkers13
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics13
13C15N: glucagon-based novel isotope dilution mass spectrometry method for measurement of glucagon metabolism in humans13
Systematic evaluation and optimization of protein extraction parameters in diagnostic FFPE specimens13
Proteome profiling of human placenta reveals developmental stage-dependent alterations in protein signature12
Redefining serological diagnostics with immunoaffinity proteomics12
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers11
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study11
Change of histone H3 lysine 14 acetylation stoichiometry in human monocyte derived macrophages as determined by MS-based absolute targeted quantitative proteomic approach: HIV infection and methamphet11
Circulating microvesicles and exosomes in small cell lung cancer by quantitative proteomics10
Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry9
Development of an ID-LC–MS/MS method using targeted proteomics for quantifying cardiac troponin I in human serum9
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients9
Changes of serum IgG glycosylation patterns in rheumatoid arthritis8
Label-free quantitative proteomic analysis of serum exosomes from patients of renal anemia: The Good and the Bad of Roxadustat8
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers8
Label-free LC–MS/MS proteomics analyses reveal proteomic changes in oxidative stress and the SOD antioxidant strategy in TM cells8
Recent progress in mass spectrometry-based urinary proteomics8
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors7
Using established biorepositories for emerging research questions: a feasibility study7
Correlation between small-cell lung cancer serum protein/peptides determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and chemotherapy efficacy7
Are the results from a multiplex proteomic assay and a conventional immunoassay for NT-proBNP and GDF-15 comparable?7
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases7
Comment on “Cerebrospinal fluid camk2a levels at baseline predict long-term progression in multiple sclerosis. Clinical Proteomics”7
Frozen tissue coring and layered histological analysis improves cell type-specific proteogenomic characterization of pancreatic adenocarcinoma7
Resistin as a potential diagnostic biomarker for sepsis: insights from DIA and ELISA analyses7
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics6
The effect of storage time and temperature on the proteomic analysis of FFPE tissue sections6
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds6
Identification of brain-enriched proteins in CSF as biomarkers of relapsing remitting multiple sclerosis6
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka6
Proteomics of prostate cancer serum and plasma using low and high throughput approaches6
Correction: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients6
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex6
Quantification of putative ovarian cancer serum protein biomarkers using a multiplexed targeted mass spectrometry assay6
Circulating proteins as predictive and prognostic biomarkers in breast cancer6
Integrating functional proteomics and next generation sequencing reveals potential therapeutic targets for Taiwanese breast cancer6
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies6
Maternal serum CFHR4 protein as a potential non-invasive marker of ventricular septal defects in offspring: evidence from a comparative proteomics study6
Associations of circulating proteins with lipoprotein profiles: proteomic analyses from the OmniHeart randomized trial and the Atherosclerosis Risk in Communities (ARIC) Study5
A SISCAPA-based approach for detection of SARS-CoV-2 viral antigens from clinical samples5
Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan5
Use of MS-GUIDE for identification of protein biomarkers for risk stratification of patients with prostate cancer5
Mapping dynamic molecular changes in hippocampal subregions after traumatic brain injury through spatial proteomics5
Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals5
Validation of ANG-1 and P-SEL as biomarkers of post-COVID-19 conditions using data from the Biobanque québécoise de la COVID-19 (BQC-19)5
Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases5
Application of urine proteomics in the diagnosis and treatment effectiveness monitoring of early-stage Mycosis Fungoides5
Optimized data-independent acquisition approach for proteomic analysis at single-cell level4
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion4
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue4
Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation4
Proteomic profiling of end-stage COVID-19 lung biopsies4
Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model4
Exploring the novel duo of Reticulocalbin, and Sideroflexin as future biomarker candidates for Exacerbated Chronic Obstructive Pulmonary Disease3
Quantitative proteomics reveals serum proteome alterations during metastatic disease progression in breast cancer patients3
Proteomic alteration of endometrial tissues during secretion in polycystic ovary syndrome may affect endometrial receptivity3
Quantitative proteomics reveals the effect of Yigu decoction (YGD) on protein expression in bone tissue3
Comparison of intact protein and digested peptide techniques for high throughput proteotyping of ApoE3
Human tear film protein sampling using soft contact lenses3
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities3
A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors3
Comparison of early changes in tear film protein profiles after small incision lenticule extraction (SMILE) and femtosecond LASIK (FS-LASIK) surgery3
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer3
Research biopsies in kidney transplantation: an evaluation of surgical techniques and optimal tissue mass allowing molecular and histological analyses3
SPOT: spatial proteomics through on-site tissue-protein-labeling3
Determination of temporal reproducibility and variability of cancer biomarkers in serum and EDTA plasma samples using a proximity extension assay3
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning3
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection3
Identification of novel proteomic biomarkers for hypertension: a targeted approach for precision medicine3
Correction to: Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources2
Candidate biomarkers for treatment benefit from sunitinib in patients with advanced renal cell carcinoma using mass spectrometry-based (phospho)proteomics2
Urine proteomics identifies biomarkers for diabetic kidney disease at different stages2
A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways2
Proteomic analysis of chromophobe renal cell carcinoma and benign renal oncocytoma biopsies reveals shared metabolic dysregulation2
Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation2
The rapid detection of procalcitonin in septic serum using immunoaffinity MALDI chips2
Cord blood platelet-rich plasma: proteomics analysis for ophthalmic applications2
Correction: Proteomic signature associated with chronic kidney disease (CKD) progression identified by data-independent acquisition mass spectrometry2
Proteomics-based evaluation of the mechanism underlying vascular injury via DNA interstrand crosslinks, glutathione perturbation, mitogen-activated protein kinase, and Wnt and ErbB signaling pathways 2
Proteomic profiling of prostate cancer reveals molecular signatures under antiandrogen treatment2
Quantitative site-specific N-glycosylation analysis reveals IgG glyco-signatures for pancreatic cancer diagnosis2
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue2
Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis2
Integrated proteomics and N-glycoproteomic characterization of glioblastoma multiform revealed N-glycosylation heterogeneities as well as alterations in sialyation and fucosylation2
Discovery of novel glioma serum biomarkers by proximity extension assay2
Airway fibrin formation cascade in allergic asthma exacerbation: implications for inflammation and remodeling2
Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer’s disease biomarkers2
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization2
Effect of dynamic exclusion and the use of FAIMS, DIA and MALDI-mass spectrometry imaging with ion mobility on amyloid protein identification2
Novel plasma protein biomarkers from critically ill sepsis patients2
Highly sensitive therapeutic drug monitoring of infliximab in serum by targeted mass spectrometry in comparison to ELISA data2
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach2
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers2
Simultaneous targeted and discovery-driven clinical proteotyping using hybrid-PRM/DIA2
Comparative proteomic analysis of glomerular proteins in IgA nephropathy and IgA vasculitis with nephritis2
Admission glucose, HbA1c levels and inflammatory cytokines in patients with acute ST-elevation myocardial infarction2
ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach2
iTRAQ-based quantitative proteomic analysis of thoracic aortas from adult rats born to preeclamptic dams2
Identification of SARS-CoV-2 biomarkers in saliva by transcriptomic and proteomics analysis2
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