OOIR: Observatory of International Research

Papers

(The TQCC of Clinical Proteomics is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Distinct proteomic profiles of clinical isolates show diversity of Pseudomonas aeruginosa colistin-resistance	211
Changes of serum IgG glycosylation patterns in rheumatoid arthritis	92
From blood drops to biomarkers: a scoping review of microsampling in mass spectrometry-based proteomics	48
Recent progress in mass spectrometry-based urinary proteomics	37
A multi-omics study reveals pathway-level insights and predictive biomarkers in pediatric TB	35
Proteome profiling of cutaneous leishmaniasis lesions due to dermotropic Leishmania donovani in Sri Lanka	32
The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies	28
Quantification of putative ovarian cancer serum protein biomarkers using a multiplexed targeted mass spectrometry assay	27
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue	27
Correction: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	24
Comparative mass spectrometry analysis of high and low centrifugation extracellular vesicle (EV) pellets from healthy urine following Tamm-Horsfall protein removal	23
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds	19
Serum proteomics for the identification of biomarkers to flag predilection of COVID19 patients to various organ morbidities	18
Mass spectrometry quantifies target engagement for a KRASG12C inhibitor in FFPE tumor tissue	17
Alterations in the pH of pancreatic juice are associated with chymotrypsin C inactivation and lithostathine precipitation in chronic pancreatitis patients: a proteomic approach	17
Nipple aspirate fluid as a proximal breast liquid biopsy platform: advancing precision risk management in breast cancer	16
An ALS assembly modulator signature in peripheral blood mononuclear cells: implications for ALS pathophysiology, therapeutics, and diagnostics	16
Elevated level of multibranched complex glycan reveals an allergic tolerance status	16
Plasma exosome proteomics reveals upregulation of CILP-1 in concave side of paraspinal muscle in adolescent idiopathic scoliosis	15
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study	15
Quantitative site-specific N-glycosylation analysis reveals IgG glyco-signatures for pancreatic cancer diagnosis	14
Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19	14
Proteomic profiles screening identified novel exosomal protein biomarkers for diagnosis of lung cancer	14
Discovery of novel glioma serum biomarkers by proximity extension assay	14
Integrated serum proteomics and metabolomics reveal an INR-associated multi-omics signature in hepatocellular carcinoma	14

Plasma proteomics in pediatric patients with sepsis– hopes and challenges	13
Targeted proteomics for the detection of androgen receptor variants in preclinical models of castration-resistant prostate cancer	13
Integrating human plasma proteomes with genome-wide association data implicates novel proteins and drug targets for rheumatoid arthritis	13
Neat plasma proteomics: getting the best out of the worst	13
Proteomics study of primary and recurrent adamantinomatous craniopharyngiomas	12
Longitudinal serum proteomics identifies inflammatory and metabolic pathways in hypertensive nephrosclerosis progression	12
Proteomic insights into the pathophysiology of hypertension-associated albuminuria: Pilot study in a South African cohort	11
Proteomic analyses reveal cystatin c is a promising biomarker for evaluation of systemic lupus erythematosus	11
Plasma proteomic profiling reveals distinct protein signatures associated with hepatocellular carcinoma in chronic hepatitis B infection	11
Plasma proteomics of extracellular vesicles identifies key proteins correlating to postoperative atrial fibrillation after coronary artery bypass surgery	11
Plasma proteomic characterization of colorectal cancer patients with FOLFOX chemotherapy by integrated proteomics technology	11
Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection	10
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides	10
Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients	10
Quantitative proteomics analysis in small cell carcinoma of cervix reveals novel therapeutic targets	10
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study	10
Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers	10
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response	10
Causal effects and mediation pathways of circulating plasma proteins on osteoporosis: a two-sample and two-step Mendelian randomization study	10
Comparative evaluation of analytical methods for CSF proteomics	10
Recent developments in mass-spectrometry-based targeted proteomics of clinical cancer biomarkers	9
Integrating functional proteomics and next generation sequencing reveals potential therapeutic targets for Taiwanese breast cancer	9
Validation of the novel GLAS algorithm as an aid in the detection of liver fibrosis and cirrhosis based on GP73, LG2m, age, and sex	9
Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach	9
Calcium-related genes predict prognosis, immune characteristics, and response to immunotherapy in LUAD patients	9
Characterizing age-related changes in intact mitochondrial proteoforms in murine hearts using quantitative top-down proteomics	9
Clinic-first sepsis recognition in the ICU: a proteomics-guided, parsimonious model with independent validation	9
Integrating multimodal data to predict the progression of hormone-sensitive prostate cancer	9
Development of a rapid and specific MALDI-TOF mass spectrometric assay for SARS-CoV-2 detection	9
Quantitative proteomic analysis of HER2 protein expression in PDAC tumors	9
Proteome profiling of cerebrospinal fluid-derived extracellular vesicles reveals potential biomarkers for drug-resistant epilepsy	9
Decreased histidine-rich glycoprotein and increased complement C4-B protein levels in follicular fluid predict the IVF outcomes of recurrent spontaneous abortion	9
ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach	9
Novel plasma protein biomarkers from critically ill sepsis patients	9
Human tear film protein sampling using soft contact lenses	8
Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization	8
Identification of adrenocorticotropic hormone–specific therapeutic biomarkers in infantile epileptic spasm syndrome using data-independent acquisition mass spectrometry	8
Evaluation of the relationship between inflammation and typical chest pain in ST-elevation myocardial infarction	8
SPOT: spatial proteomics through on-site tissue-protein-labeling	8
Proteomic analysis of plasma exosomes in patients with metastatic colorectal cancer	8
An LC–MS-based designated comparison method with similar performance to the Lp(a) reference measurement procedure to guide molar Lp(a) standardization	8
Closing the gaps in patient management of dyslipidemia: stepping into cardiovascular precision diagnostics with apolipoprotein profiling	8
Proteomic and phosphoproteomic signatures of disease progression in unmutated IGHV chronic lymphocytic leukemia	8
Urinary exosomal RAB11A serves as a novel non-invasive biomarker for diagnosis, treatment response monitoring, and prognosis in small cell lung cancer	8
Glial cell proteome using targeted quantitative methods for potential multi-diagnostic biomarkers	8
Spatial proteomics to discover aging-associated alterations in the renal tubulointerstitium	8