OOIR: Observatory of International Research

Papers

(The H4-Index of IEEE-ACM Transactions on Computational Biology and Bioinformatics is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Gene Co-Expression Networks Offer New Perspectives on Sepsis Pathophysiology	528
Row and Column Structure-Based Biclustering for Gene Expression Data	271
Inference of a Dynamic Aging-related Biological Subnetwork via Network Propagation	146
Data-Driven and Knowledge-Based Algorithms for Gene Network Reconstruction on High-Dimensional Data	113
New Labeling Methods for Deep Learning Real-Valued Inter-Residue Distance Prediction	96
POPBic: Pathway-Based Order Preserving Biclustering Algorithm Towards the Analysis of Gene Expression Data	96
Prediction of Transcription Factor Binding Sites With an Attention Augmented Convolutional Neural Network	85
RNASeqR: An R Package for Automated Two-Group RNA-Seq Analysis Workflow	84
Contrasting Multi-Source Temporal Knowledge Graphs for Biomedical Hypothesis Generation	75
Protein-Protein Interaction Sites Prediction Using Batch Normalization Based CNNs and Oversampling Method Borderline-SMOTE	68
Seq-BEL: Sequence-Based Ensemble Learning for Predicting Virus-Human Protein-Protein Interaction	67
An Ensemble Tf-Idf Based Approach to Protein Function Prediction via Sequence Segmentation	66
IPP: An Intelligent Privacy-Preserving Scheme for Detecting Interactions in Genome Association Studies	66
Graph Convolutional Auto-Encoders for Predicting Novel lncRNA-Disease Associations	65
GraphPlas: Refined Classification of Plasmid Sequences Using Assembly Graphs	64
Higher-Order Proximity-Based MiRNA-Disease Associations Prediction	63
Protein Fold Recognition by Combining Support Vector Machines and Pairwise Sequence Similarity Scores	59
scBKAP: A Clustering Model for Single-Cell RNA-Seq Data Based on Bisecting K-Means	58
An Effective Swarm Intelligence Optimization Algorithm for Flexible Ligand Docking	56
An Automated Cell Tracking Approach With Multi-Bernoulli Filtering and Ant Colony Labor Division	54
Compressed Sparse FM-Index: Fast Sequence Alignment Using Large K-Steps	54
Analysis of Cancer-Associated Mutations of POLB Using Machine Learning and Bioinformatics	53
ELMo4m6A: A Contextual Language Embedding-Based Predictor for Detecting RNA N6-Methyladenosine Sites	53
IGNSCDA: Predicting CircRNA-Disease Associations Based on Improved Graph Convolutional Network and Negative Sampling	51
Hybrid Projective Synchronization via PI Controller Based on DNA Strand Displacement	51

VMF-SSD: A Novel V-Space Based Multi-Scale Feature Fusion SSD for Apple Leaf Disease Detection	51
The Determination of Distinctive Single Nucleotide Polymorphism Sets for the Diagnosis of Behçet's Disease	50
Modality-DTA: Multimodality Fusion Strategy for Drug–Target Affinity Prediction	49
Predicting Drug-Drug Interactions Based on Integrated Similarity and Semi-Supervised Learning	49
State Observer Design of Coupled Genetic Regulatory Networks With Reaction-Diffusion Terms via Time-Space Sampled-Data Communications	48
Prediction of circRNA-MiRNA Association Using Singular Value Decomposition and Graph Neural Networks	48
Improving Biomedical Question Answering by Data Augmentation and Model Weighting	48
Local R-Symmetry Co-Occurrence: Characterising Leaf Image Patterns for Identifying Cultivars	46
An Approach of Epistasis Detection Using Integer Linear Programming Optimizing Bayesian Network	46
Analyzing Effect of Multi-Modality in Predicting Protein-Protein Interactions	45
Spatial Stochastic Model of the Pre-B Cell Receptor	45
Minimum Functional Length Analysis of K-Mer Based on BPNN	45
Optimized Elastic Network Models With Direct Characterization of Inter-Residue Cooperativity for Protein Dynamics	44
PseU-KeMRF: A Novel Method for Identifying RNA Pseudouridine Sites	42
Blockchain-Based Data Access Security Solutions for Medical Wearables	42
SGNet: Sequence-Based Convolution and Ligand Graph Network for Protein Binding Affinity Prediction	42
Automated Spot Counting in Microbiology	41
Feature Fusion GAN Based Virtual Staining on Plant Microscopy Images	41
A Multi-Task Deep Feature Selection Method for Brain Imaging Genetics	41
Subgroup Identification Using Virtual Twins for Human Microbiome Studies	41
Fine-Grained Lesion Classification Framework for Early Auxiliary Diagnosis	41