OOIR: Observatory of International Research

Papers

(The H4-Index of IEEE-ACM Transactions on Computational Biology and Bioinformatics is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Gene Co-Expression Networks Offer New Perspectives on Sepsis Pathophysiology	531
Row and Column Structure-Based Biclustering for Gene Expression Data	278
Inference of a Dynamic Aging-related Biological Subnetwork via Network Propagation	150
Data-Driven and Knowledge-Based Algorithms for Gene Network Reconstruction on High-Dimensional Data	120
New Labeling Methods for Deep Learning Real-Valued Inter-Residue Distance Prediction	96
POPBic: Pathway-Based Order Preserving Biclustering Algorithm Towards the Analysis of Gene Expression Data	96
Prediction of Transcription Factor Binding Sites With an Attention Augmented Convolutional Neural Network	87
RNASeqR: An R Package for Automated Two-Group RNA-Seq Analysis Workflow	85
Contrasting Multi-Source Temporal Knowledge Graphs for Biomedical Hypothesis Generation	78
An Automated Cell Tracking Approach With Multi-Bernoulli Filtering and Ant Colony Labor Division	71
Protein Fold Recognition by Combining Support Vector Machines and Pairwise Sequence Similarity Scores	67
An Effective Swarm Intelligence Optimization Algorithm for Flexible Ligand Docking	67
Higher-Order Proximity-Based MiRNA-Disease Associations Prediction	67
scBKAP: A Clustering Model for Single-Cell RNA-Seq Data Based on Bisecting K-Means	67
GraphPlas: Refined Classification of Plasmid Sequences Using Assembly Graphs	67
Compressed Sparse FM-Index: Fast Sequence Alignment Using Large K-Steps	65
An Ensemble Tf-Idf Based Approach to Protein Function Prediction via Sequence Segmentation	61
IPP: An Intelligent Privacy-Preserving Scheme for Detecting Interactions in Genome Association Studies	61
Graph Convolutional Auto-Encoders for Predicting Novel lncRNA-Disease Associations	58
The Determination of Distinctive Single Nucleotide Polymorphism Sets for the Diagnosis of Behçet's Disease	55
Analysis of Cancer-Associated Mutations of POLB Using Machine Learning and Bioinformatics	55
Hybrid Projective Synchronization via PI Controller Based on DNA Strand Displacement	55
Predicting Drug-Drug Interactions Based on Integrated Similarity and Semi-Supervised Learning	54
IGNSCDA: Predicting CircRNA-Disease Associations Based on Improved Graph Convolutional Network and Negative Sampling	53
Prediction of circRNA-MiRNA Association Using Singular Value Decomposition and Graph Neural Networks	53

ELMo4m6A: A Contextual Language Embedding-Based Predictor for Detecting RNA N6-Methyladenosine Sites	53
VMF-SSD: A Novel V-Space Based Multi-Scale Feature Fusion SSD for Apple Leaf Disease Detection	51
Seq-BEL: Sequence-Based Ensemble Learning for Predicting Virus-Human Protein-Protein Interaction	50
Modality-DTA: Multimodality Fusion Strategy for Drug–Target Affinity Prediction	49
Improving Biomedical Question Answering by Data Augmentation and Model Weighting	49
Protein-Protein Interaction Sites Prediction Using Batch Normalization Based CNNs and Oversampling Method Borderline-SMOTE	49
State Observer Design of Coupled Genetic Regulatory Networks With Reaction-Diffusion Terms via Time-Space Sampled-Data Communications	49
CIPHER-SC: Disease-Gene Association Inference Using Graph Convolution on a Context-Aware Network With Single-Cell Data	48
Local R-Symmetry Co-Occurrence: Characterising Leaf Image Patterns for Identifying Cultivars	48
Optimized Elastic Network Models With Direct Characterization of Inter-Residue Cooperativity for Protein Dynamics	47
Evaluation of Existing Methods for High-Order Epistasis Detection	47
Deep Learning in Gene Regulatory Network Inference: A Survey	47
Self-Supervised Learning for Label Sparsity in Computational Drug Repositioning	46
Robust and Privacy-Preserving Decentralized Deep Federated Learning Training: Focusing on Digital Healthcare Applications	46
Minimum Functional Length Analysis of K-Mer Based on BPNN	43
Transfer Learning Based Lightweight Ensemble Model for Imbalanced Breast Cancer Classification	42
A Neighborhood-Based Global Network Model to Predict Drug-Target Interactions	42
Identifying Molecular Biomarkers for Diseases With Machine Learning Based on Integrative Omics	42