OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Structural & Molecular Biology is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane	472
Author Correction: Polλ promotes microhomology-mediated end-joining	287
Author Correction: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site	239
Shifting our perspective on orphan G protein-coupled receptors	203
Celebrating Nature Structural & Molecular Biology’s 30th anniversary	136
Protein import into mitochondria — a new path through the membranes	134
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens	134
Snapshots of actin and tubulin folding inside the TRiC chaperonin	130
Accessible technology for diploid high-order 3D human genome analysis	110
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex	96
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies	93
Surviving under stress conditions	92
Structures of aberrant spliceosome intermediates on their way to disassembly	91
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos	88
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)	83
Towards a molecular and structural definition of cell death	83
P-type ATPase magnesium transporter MgtA acts as a dimer	81
TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization	80
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients	79
Exploration of novel αβ-protein folds through de novo design	78
Structural insights into translocation and tailored synthesis of hyaluronan	78
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism	78
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging	76
Endocrine resistance and breast cancer plasticity are controlled by CoREST	74
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport	73

Structural basis of branching during RNA splicing	72
Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation	68
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication–transcription complex	67
PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair	66
Structural insights into metazoan pretargeting GET complexes	66
Current challenges in understanding the role of enhancers in disease	65
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction	65
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch	65
30 years of structural and molecular biology and counting	62
Constitutive activation mechanism of a class C GPCR	62
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase	60
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer	59
Structure of the HCV glycoprotein	58
Transcription directionality is licensed by Integrator at active human promoters	58
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring	58
Binding NEMO: Liquid–liquid phase separation captures immune regulator	57
Studying the impact of the nuclear topography on gene function	57
EGOC inhibits TOROID polymerization by structurally activating TORC1	56
Cohesin closes the door on coexpression	55
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex	54
Author Correction: Structural basis of the histone ubiquitination read–write mechanism of RYBP–PRC1	54
Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM	54
Author Correction: Cryo-EM structure of an active central apparatus	54
Signal-induced enhancer activation requires Ku70 to read topoisomerase1–DNA covalent complexes	53
Phase separation drives X-chromosome inactivation	53
SCAF1 drives the compositional diversity of mammalian respirasomes	53
Understanding ubiquitination in neurodevelopment by integrating insights across space and time	52
Comprehensive analysis of Saccharomyces cerevisiae intron structures in vivo	52
Smc5/6 silences episomal transcription by a three-step function	52
A conserved coupling of transcriptional ON and OFF periods underlies bursting dynamics	52