OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Structural & Molecular Biology is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Target practice: first Piwi structure with RNA	555
Aging RNA Polymerase II may speed recklessly	397
The activated inflammasome	270
Musings on art and science	256
LiBERating PARP1	200
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring	185
Building a molecular rotor	170
Networking counters stress	166
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53	158
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase	140
Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro	134
VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains	117
MAVS deSUMOylation by SENP1 inhibits its aggregation and antagonizes IRF3 activation	117
Embracing change	116
Structure of the HCV glycoprotein	113
Molecular basis of Gabija anti-phage supramolecular assemblies	112
Structure of the γ-tubulin ring complex-capped microtubule	112
An egg-ceptional mechanism of acentrosomal spindle assembly	105
How one molecule senses light and temperature	105
Two rings to fold them	104
Cryo-EM for protein discovery	82
Celebrating Nature Structural & Molecular Biology’s 30th anniversary	80
Structural basis of branching during RNA splicing	77
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies	76
Computational design of non-porous pH-responsive antibody nanoparticles	74

Conformational changes in heat- and proton-sensing ion channel in centipedes	74
Multidomain interactions and ring opening of the p97 ATPase by the UBXD1 adapter	73
Space exploration: finding new protein conformations using AlphaFold2	73
Atomic ribosome activity	72
Exposing chromothripsis	71
The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery	70
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex	70
ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy	70
A structural model of a Ras–Raf signalosome	70
Single-cell joint analysis of gene expression and histone modifications in droplets	69
Tagging insulin mRNA for translation	67
Mammalian CCR4–NOT binds and ubiquitinates 80S ribosomes to enforce translational stalling	66
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)	65
Multiple allosteric mechanisms suppress PRC2 activity at active genes	65
A nuclear pore-anchored condensate enables germ granule organization and transgenerational epigenetic inheritance	64
Mutant tau filaments from some inherited frontotemporal dementias show the Alzheimer fold	63
Structural basis of the mechanism and inhibition of a human ceramide synthase	62
The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1	61
Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23	60
Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation	60
Cryo-EM structure of the heteromeric TRPC1/TRPC4 channel	60
Supporting structural biologists in Africa requires resources and capacity building	59
Structural insights into SV2A and the mechanism of racetam anticonvulsants	59
Structural insights into double-stranded RNA recognition and transport by SID-1	57
Transcription directionality is licensed by Integrator at active human promoters	57
ISWI catalyzes nucleosome sliding in condensed nucleosome arrays	57
Structure of the poxvirus core	53
Illuminating cortactin structure and function at actin filament branches	53