OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Structural & Molecular Biology is 55. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane	522
Author Correction: Polλ promotes microhomology-mediated end-joining	304
Author Correction: Structure of the human K2P13.1 channel reveals a hydrophilic pore restriction and lipid cofactor site	214
Celebrating Nature Structural & Molecular Biology’s 30th anniversary	150
30 years of structural and molecular biology and counting	146
Towards a molecular and structural definition of cell death	140
Accessible technology for diploid high-order 3D human genome analysis	126
Surviving under stress conditions	107
TRIM37 prevents ectopic spindle pole assembly by peptide motif recognition and substrate-dependent oligomerization	107
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch	99
Structure of the HCV glycoprotein	98
ACAD10 and ACAD11 enable mammalian 4-hydroxy acid lipid catabolism	94
Isoform-resolved mRNA profiling of ribosome load defines interplay of HIF and mTOR dysregulation in kidney cancer	89
Structures of aberrant spliceosome intermediates on their way to disassembly	89
Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex	89
P-type ATPase magnesium transporter MgtA acts as a dimer	88
Constitutive activation mechanism of a class C GPCR	87
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens	84
Shifting our perspective on orphan G protein-coupled receptors	84
Gene regulation through exon junction complex modularity	78
Exploration of novel αβ-protein folds through de novo design	77
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport	75
Current challenges in understanding the role of enhancers in disease	75
Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication–transcription complex	74
Transcription directionality is licensed by Integrator at active human promoters	72

Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring	71
Endocrine resistance and breast cancer plasticity are controlled by CoREST	70
Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation	70
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase	70
Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos	70
Uncovering protein glycosylation dynamics and heterogeneity using deep quantitative glycoprofiling (DQGlyco)	69
Structural insights into translocation and tailored synthesis of hyaluronan	68
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies	66
Snapshots of actin and tubulin folding inside the TRiC chaperonin	66
Protein import into mitochondria — a new path through the membranes	64
Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging	62
PARylated PDHE1α generates acetyl-CoA for local chromatin acetylation and DNA damage repair	62
A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients	61
Structural basis of branching during RNA splicing	61
A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction	61
Studying the impact of the nuclear topography on gene function	60
Binding NEMO: Liquid–liquid phase separation captures immune regulator	60
Cohesin closes the door on coexpression	59
Author Correction: Structural basis of the histone ubiquitination read–write mechanism of RYBP–PRC1	59
Lineage regulators TFAP2C and NR5A2 function as bipotency activators in totipotent embryos	58
Author Correction: Cryo-EM structure of an active central apparatus	58
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex	58
Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport	57
EGOC inhibits TOROID polymerization by structurally activating TORC1	57
DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation	57
Control of transcription elongation and DNA repair by alarmone ppGpp	57
SCAF1 drives the compositional diversity of mammalian respirasomes	57
Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels	56
Phase separation drives X-chromosome inactivation	55
A personal perspective of the voltage-gated potassium channel studies	55
Better SIFI than sorry	55
THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development	55
Chemical modifications, ions and water molecules in the sub-2 Å resolution structure of the human 80S ribosome	55
Transcription start site choice diversifies mRNA isoforms and defines cancer cell behavior	55