OOIR: Observatory of International Research

Papers

(The TQCC of Nanomedicine-Nanotechnology Biology and Medicine is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Robust aptamer-targeted CRISPR/Cas9 delivery using mesenchymal stem cell membrane –liposome hybrid: BIRC5 gene knockout against melanoma	68
Corrigendum to “A light-up “G-quadruplex nanostring” for label-free and selective detection of miRNA via duplex-specific nuclease mediated tandem rolling circle amplification” [Nanomed.: Nanotechnol.	65
A novel bidirectional perfusion-like administered system for NIR-II fluorescence imaging precision diagnosis of bladder cancer	59
Macrophage membrane modified baicalin liposomes improve brain targeting for alleviating cerebral ischemia reperfusion injury	54
Comparative examination of the chemistry and biology of AI-driven gold NPs in Theranostics: New insights into biosensing, bioimaging, genomics, diagnostics, and therapy	50
Engineered photonic near-infrared light activated photothermal theranostic nanovaccine induced targeted remodeling of tumor microenvironment	50
Delivery of gene editing therapeutics	43
Dye labeling for optical imaging biases drug carriers' biodistribution and tumor uptake	40
Diethyldithiocarbamate copper nanoparticle overcomes resistance in cancer therapy without inhibiting P-glycoprotein	37
Therapeutic effects of cationic liposomes on lupus-prone MRL/lpr mice are mediated via inhibition of TLR4-triggered B-cell activation	35
Peroxidase modification-driven silymarin liposomes for the treatment of liver fibrosis	34
Novel combination of bioactive agents in bilayered dermal patches provides superior wound healing	34
Determination of spectroscopy marker of atherosclerotic carotid stenosis using FTIR-ATR combined with machine learning and chemometrics analyses	32
In vitro assessment of nanomedicines' propensity to cause palmar-plantar erythrodysesthesia: A Doxil vs. doxorubicin case study	30
Coatsome-replicon vehicles: Self-replicating RNA vaccines against infectious diseases	29
Chitosan-covered calcium phosphate particles as a drug vehicle for delivery to the eye	27
Electrospun electroconductive constructs of aligned fibers for cardiac tissue engineering	25
Cyclo(RGD) peptide-decorated silver nanoparticles with anti-platelet potential for active platelet-rich thrombus targeting	25
Exploiting the preferential phagocytic uptake of nanoparticle-antigen conjugates for the effective treatment of autoimmunity	24
Poly(lipoic acid)-based nanoparticles as a new therapeutic tool for delivering active molecules	24
Targeting prostate cancer with Clostridium perfringens enterotoxin functionalized nanoparticles co-encapsulating imaging cargo enhances magnetic resonance imaging specificity	24
Intrinsic variability of fluorescence calibrators impacts the assignment of MESF or ERF values to nanoparticles and extracellular vesicles by flow cytometry	23
Potential nanotechnology-based diagnostic and therapeutic approaches for Meniere's disease	23
Turning down the heat: The case for mild hyperthermia and thermosensitive liposomes	22
Cerium oxide nanoparticle conjugation to microRNA-146a mechanism of correction for impaired diabetic wound healing	22

HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties	21
Corrigendum to “Novel oral nano-hepatic targeted anti-PCSK9 in hypercholesterolemia” [Nanomedicine 40 (2022 Feb); 102480. doi: 10.1016/j.nano.2021.102480]	21
A novel treatment for diabetic nephropathy: Folate receptor-targeted delivery of TLR4 siRNA via functionalized PLGA nanoparticles in streptozotocin-induced diabetic murine models	21
Chemical modification of bradykinin-polymer conjugates for optimum delivery of nanomedicines to tumors	20
Enzyme-triggered antigen release enhances cross-presentation by dendritic cells	20
Oxygen-independent alkyl radical nanogenerator enhances breast cancer therapy	20
Combinatorial cetuximab targeted polymeric nanocomplexes reduce PRC1 level and abrogate growth of metastatic hepatocellular carcinoma in vivo with efficient radionuclide uptake	20
Anti-stokes luminescent organic nanoparticles for frequency upconversion biomedical imaging	19
Research progress on the application of nanomaterials in the diagnosis and treatment of venous thromboembolism	19
Superparamagnetic iron oxide nanoparticles-based detection of neuronal activity	19
Corrigendum to “construction of bionanoparticles based on Angelica polysaccharides for the treatment of stroke” [nanomedicine: Nanotechnology, biology and medicine 44 (2022) 102570]	18
Brain peptides modified exosome-mediated drug delivery system for adriamycin-induced nephropathy treatment	18
Constructing a blood contact material surface with selective adhesion of multiple cells using TiO2 photocatalytic oxidation of polydopamine	18
Pluronic F127 hydrogel-loaded extracellular vesicles from adipose-derived mesenchymal stem cells promote tracheal cartilage regeneration via SCNN1B delivery	17
Transdermal nanolipoplex simultaneously inhibits subcutaneous melanoma growth and suppresses systemically metastatic melanoma by activating host immunity	17
Combination of local immunogenic cell death-inducing chemotherapy and DNA vaccine increases the survival of glioblastoma-bearing mice	17
Accelerated neutral atom beam (ANAB) modified polyethylene for decreased wear and reduced bacteria colonization: An in vitro study	17
Transferrin receptors/magnetic resonance dual-targeted nanoplatform for precise chemo-photodynamic synergistic cancer therapy	17
Enhanced cartilage regeneration by icariin and mesenchymal stem cell-derived extracellular vesicles combined in alginate-hyaluronic acid hydrogel	17
Polylactic acid based polymeric nanoparticle mediated co-delivery of navitoclax and decitabine for cancer therapy	17
Development of nanoparticles and quantum dots as alternatives to iodinated contrast agents for mono-modal and bi-modal computed tomography imaging	16
CAQK modification enhances the targeted accumulation of metformin-loaded nanoparticles in rats with spinal cord injury	16
Surfactant free synthesis of cationic nano-vesicles: A safe triple drug loaded vehicle for the topical treatment of cutaneous leishmaniasis	16
Two-component T-cell immunotherapy enables antigen pre-targeting to reduce cytokine release without forfeiting efficacy	16
Modification of mesenchymal stromal cells with silibinin-loaded PLGA nanoparticles improves their therapeutic efficacy for cutaneous wound repair	16
4HPR nanoformulation regulates MAPKAPK3/3pK signaling to control Bax phosphorylation and mitochondrial translocation to execute apoptosis in neuroblastoma	16
A nanomechanical strategy involving focal adhesion kinase for overcoming drug resistance in breast cancer	16
Therapeutic potential of combating cancer by restoring wild-type p53 through mRNA nanodelivery	16
Isotope labeled 3D-Raman confocal imaging and atomic force microscopy study on epithelial cells interacting with the fungus Candida albicans	16
Synthetic peptides of IL-1Ra and HSP70 have anti-inflammatory activity on human primary monocytes and macrophages: Potential treatments for inflammatory diseases	16
Repurposing pentamidine using hyaluronic acid-based nanocarriers for skeletal muscle treatment in myotonic dystrophy	15
A novel surface functionalization platform to prime extracellular vesicles for targeted therapy and diagnostic imaging	15
Modular nanoarray vaccine for SARS-CoV-2	15
Protective effect of MSC-derived exosomes against cisplatin-induced apoptosis via heat shock protein 70 in auditory explant model	15
Gold nanoparticles associated with ovalbumin as adjuvant in the indirect effects of oral tolerance improve ear wound healing in mice	15
Bioavailability by design — Vitamin D3 liposomal delivery vehicles	15
Neuroprotective macromolecular methylprednisolone prodrug nanomedicine prevents glucocorticoid-induced muscle atrophy and osteoporosis in a rat model of spinal cord injury	14
Antisense locked nucleic acid gapmers to control Candida albicans filamentation	14
Downregulation of exosomal MHC-I promotes glioma cells escaping from systemic immunosurveillance	14
Vesicles of yeast cell wall-sitagliptin to alleviate neuroinflammation in Alzheimer's disease	14
Tumor-targeting albumin nanoparticles as an efficacious drug delivery system and potential diagnostic tool in non-muscle-invasive bladder cancer therapy	14
Efficient enrichment of free target sequences in an integrated microfluidic device for point-of-care detection systems	14
Ultrasmall polymer-coated cerium oxide nanoparticles as a traumatic brain injury therapy	14
MoO3-X nanodots coated suture for combating surgical site infection via antibacterial and anti-inflammatory properties	14
Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines	14
Bacteria-derived outer membrane vesicles engineered with over-expressed pre-miRNA as delivery nanocarriers for cancer therapy	14
Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration	14
Peptide mediated targeted delivery of gold nanoparticles into the demyelination site ameliorates myelin impairment and gliosis	13
DNA-gold nanoprobe-based integrated biosensing technology for non-invasive liquid biopsy of serum miRNA: A new frontier in prostate cancer diagnosis	13
Overcoming the blood–brain barrier by using a multistage exosome delivery system to inhibit central nervous system lymphoma	13

Development of a porous layer-by-layer microsphere with branched aliphatic hydrocarbon porogens	13
Optical biosensing of markers of mucosal inflammation	13
Membrane cholesterol enrichment and folic acid functionalization lead to increased accumulation of erythrocyte-derived optical nano-constructs within the ovarian intraperitoneal tumor implants in mice	13
Ligand-displaying-exosomes using RNA nanotechnology for targeted delivery of multi-specific drugs for liver cancer regression	13
Highly sensitive detection of three protein toxins via SERS-lateral flow immunoassay based on SiO2@Au nanoparticles	13
Customizing biomimetic surface attributes of dendritic lipopeptide nanoplatforms for extended circulation	13
Scavenger receptor-AI targeted theranostic nanoparticles for regression of atherosclerotic plaques via ABCA1 modulation	12
Diversifying the skin cancer-fighting worthwhile frontiers: How relevant are the itraconazole/ascorbyl palmitate nanovectors?	12
Photodynamic therapy associated with nanomedicine strategies for treatment of human squamous cell carcinoma: A systematic review and meta-analysis	12
Wound healing activity of aqueous dispersion of fullerene C60 produced by “green technology”	12
Systemic biodistribution and hepatocyte-specific gene editing with CRISPR/Cas9 using hyaluronic acid-based nanoparticles	12
Antitumor effect of nanophotothermolysis mediated by zinc phthalocyanine particles	12
Synthetic high-density lipoprotein nanoparticles delivering rapamycin for the treatment of age-related macular degeneration	12
Platelet–neutrophil hybrid membrane-coated gelatin nanoparticles for enhanced targeting ability and intelligent release in the treatment of non-alcoholic steatohepatitis	12
Cerium dioxide, a Jekyll and Hyde nanomaterial, can increase basal and decrease elevated inflammation and oxidative stress	12
Brain-targeting redox-sensitive micelles for codelivery of TMZ and β-lapachone for glioblastoma therapy	12
Encapsulation into hyaluronic acid-based nanogels improves the selectivity index of the snake cathelicidin Ab-Cath	12
Design and synthesis of GRPR-targeted PET probes based on Dar derivatives for imaging of prostate cancer	11
Organization of collagen fibers and tissue hardening: Markers of fibrotic scarring after spinal cord injury in mice revealed by multiphoton-atomic force microscopy imaging	11
Emerging nanotechnologies in cardiovascular medicine	11
Nanomaterials in anticancer applications and their mechanism of action - A review	11
Sequential flash nanocomplexation and flash nanoprecipitation enables scalable assembly of doxorubicin-loaded nanoparticles	11
Delivery of Mir-196c-3p with NIR-II light-triggered gel attenuates cardiomyocyte ferroptosis in cardiac ischemia-reperfusion injury	11
Carborane bearing pullulan nanogel-boron oxide nanoparticle hybrid for boron neutron capture therapy	11
Enhanced rivastigmine delivery through nanoemulsion and pyridoxine supplementation: An in-vivo study on Alzheimer's disease intervention	11
Optical detection of atherosclerosis at molecular level by optical coherence tomography: An in vitro study	11
An antigen-targeting assay for Lyme disease: Combining aptamers and SERS to detect the OspA protein	11
Small molecule based EGFR targeting of biodegradable nanoparticles containing temozolomide and Cy5 dye for greatly enhanced image-guided glioblastoma therapy	11