Contemporary Clinical Trials

Article	Citations
Publication rates in small German trials remained low five years after trial completion	93
Optimizing retention strategies for opioid use disorder pharmacotherapy: The retention phase of the CTN-0100 trial (RDD)	63
Effects of fermented and fiber-rich foods on maternal & offspring microbiome study (FeFiFo-MOMS) — Study design and methods	58
Effectiveness of pelvic floor muscle training alone or combined with either a novel biofeedback device or conventional biofeedback for improving stress urinary incontinence: A randomized controlled pi	51
“Tiny Cargo, Big Deal! Abróchame Bien, Cuídame Bien”, an emergency department-based intervention to promote child passenger safety: Protocol for an adaptive randomized trial among caregivers of 6-mont	49
Capnography-Assisted Learned, Monitored (CALM) breathing therapy for dysfunctional breathing in COPD: A bridge to pulmonary rehabilitation	43
Should studies with no events in both arms be excluded in evidence synthesis?	41
REFINE (REduced Frequency ImmuNE checkpoint inhibition in cancers): A multi-arm phase II basket trial testing reduced intensity immunotherapy across different cancers	40
Editorial Board	39
A pilot study of a school lunchroom intervention in a predominantly Latinx sample	39
‘eatNplay’ – a rurally-tailored, family-based, telehealth intervention for childhood obesity: Protocol for a mixed-methods randomized newsletter controlled pilot study	30
Editorial Board	30
Design and feasibility of a double-blind, randomized trial of peri-operative methylnaltrexone for postoperative ileus prevention after adult spinal arthrodesis	29
The use of telecommunication and virtualization among ongoing and discontinued COVID-19 clinical trials: A cross-sectional analysis	28
The Perioperative Pain Self-Management (PePS) randomized controlled trial protocol: Preventing chronic post-surgical pain and prolonged opioid use	27
COMbined Exercise Trial (COMET) to improve cognition in older adults: Rationale and methods	27
Editorial Board	25
Integrating non-concurrent controls in the analyses of late-entry experimental arms in multi-arm trials with a shared control group in the presence of parameter drift	24
Editorial Board	23
Editorial Board	23
Editorial Board	22
Design of the National Adaptive Trial for PTSD-related Insomnia (NAP Study), VA Cooperative Study Program (CSP) #2016	21
Editorial Board	20
Defining demographic cohorts in clinical trial populations using large electronic health records databases	20
Translingual neurostimulation combined with physical therapy to improve walking and balance in multiple sclerosis (NeuroMSTraLS): Study protocol for a randomized controlled trial	20

Successful recruitment of monolingual Spanish speaking Latinos to university phase II and III outpatient COVID-19 clinical treatment trials in Northern California	20
Leveraging external evidence using Bayesian hierarchical model and propensity score in the presence of covariates	19
A self-management plus mind body intervention for adolescents and young adults with type 2 diabetes: Trial design and methodological report	19
A protocol for a wait list control trial of an intervention to improve pain and depressive symptoms among middle-aged and older African American women	19
Neurologic music therapy combined with EEG-tDCS for upper motor extremity performance in patients with corticobasal syndrome: Study protocol for a novel approach	18
Editorial Board	18
Comparison of baseline covariate adjustment methods for restricted mean survival time	18
Editorial Board	17
Preterm-birth-prevention with Lactobacillus crispatus oral probiotics: Protocol for a double blinded randomised placebo-controlled trial (the PrePOP study)	17
The association between non-English primary language and COVID-19 clinical trial eligibility and enrollment: A retrospective cohort study	17
Editorial Board	16
Simplification or simulation: Power calculation in clinical trials	16
Iterative approaches to the use of electronic health records data for large pragmatic studies	16
Randomized clinical trials of weight loss: Pragmatic and digital strategies and innovations	16
Design of a pragmatic randomized implementation effectiveness trial testing a health system wide hypertension program for older adults	16
Participatory intervention to improve nutrition and physical activity of school-age children in Mexico	16
Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The “PRONE” Study	16
Comparative effectiveness of mobile health smoking cessation approaches among underserved patients in primary care: Study protocol for the PROMOTE-UP trial	16
Corrigendum to “Intervention to reduce barriers to type 1 diabetes self-management: Diabetes Journey study design and participant characteristics” [Contemporary Clinical Trials 152 (2025) 107849].	16
Individualized Coordination and Empowerment for Care Partners of Persons with Dementia (ICECaP): Feasibility and acceptability	16
Design of a pragmatic clinical trial to improve screening and treatment for opioid use disorder in primary care	16
Remote clinical trial to test mechanisms of ‘practice quitting’ treatment: Trial design and methodological report	15
Is exergaming a viable exercise option for obese black women?	15
Comparative effectiveness of two-way caring contacts texts vs one-way caring contacts texts vs enhanced usual care to reduce suicidal behavior in adolescents and adults: Protocol for the SPRING pragma	15
Defining optimal treatment for recurrent Clostridioides difficile infection (OpTION study): A randomized, double-blind comparison of three antibiotic regimens for patients with a first or second recur	15
Corrigendum to “Reopening schools safely and educating youth (ROSSEY) study: Protocol for a community-based, cluster randomized controlled trial” [Contemporary Clinical Trials, 139 (2024) 107480]	15
Comparative effectiveness of safety planning intervention with instrumental support calls (ISC) versus safety planning intervention with two-way text message caring contacts (CC) in adolescents and ad	15
Do better nights lead to better days? Guided internet-based cognitive behavioral therapy for insomnia in people suffering from a range of mental health problems: Protocol of a pragmatic randomized cli	15
Editorial Board	15
Electronic health record based population health management to optimize care in CKD: Design of the Kidney Coordinated HeAlth Management Partnership (K-CHAMP) trial	15
Assessing readiness to use electronic health record data for outcome ascertainment in clinical trials – A case study	14
A protocol for a cluster randomized trial of care delivery models to improve the quality of smoking cessation and shared decision making for lung cancer screening	14
A culturally tailored intervention to reduce risk of alcohol-exposed pregnancies in American Indian communities: Rationale, design, and methods	14
Design and methods of a randomized controlled trial evaluating the effects of the PE Coach mobile application on prolonged exposure among veterans with PTSD	14
Effects of a motor and cognitive training program on executive function and different biomarkers related to muscle-brain crosstalk in breast cancer survivors: 3-arm randomised controlled BRAINonFIT st	14
Editorial Board	14
Study protocol: The Maternal Health Multilevel Intervention for Racial Equity (Maternal Health MIRACLE) Project	14
Mitigating the health effects of systemic racism: Evaluation of the Race-Based Stress and Trauma Empowerment intervention	14
Designing a Bayesian adaptive clinical trial to evaluate novel mechanical ventilation strategies in acute respiratory failure using integrated nested Laplace approximations	13
Study protocol for a randomized controlled trial comparing two low-intensity weight loss maintenance interventions based on acceptance and commitment therapy or self-regulation	13
Preventing diabetes in Latino families: A protocol for a randomized control trial	13
Facilitating communication for critically ill patients and their family members: Study protocol for two randomized trials implemented in the U.S. and France	13
Study Protocol: Predicting the Quality of Response to Specific Treatments (PQRST) in Chronic Graft-versus-Host Disease	13
Patient-centered mobile health technology intervention to improve self-care in patients with chronic heart failure: Protocol for a feasibility randomized controlled trial	13
Pharmacogenomics-guided supportive oncology: A tale of two trials	13
Implementing weight maintenance with existing staff and electronic health record tools in a primary care setting: Baseline results from the MAINTAIN PRIME trial	13
Growth and adiposity in newborns study (GAINS): The influence of prenatal DHA supplementation protocol	13
The link between vitamin D and COVID-19	13
On the Move in the community: Protocol for a hybrid 1 trial examining effectiveness and fidelity of a community-based group exercise program for older adults	12
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response (SCEPTER), a pragmatic trial for conservative chronic low back pain treatment	12

Protocol for a study on itting with nterruption and Whole-Body ardiovascular ealth (SWITCH) in middle-aged adults	12
A digital health intervention to improve nutrition and physical activity in breast cancer survivors: Rationale and design of the Cook and Move for Your Life pilot and feasibility randomized controlled	12
Short messaging service (SMS) texting for uncontrolled diabetes among persons experiencing homelessness: Study protocol for a randomized trial	12
Evaluation of the efficacy and mechanisms of a novel intervention for chronic pain tailored to people with HIV: The STOMP protocol	12
Protocol for a pragmatic trial testing a self-directed lifestyle program targeting weight loss among patients with obstructive sleep apnea (POWER Trial)	12
Protocol: Implementation evaluation of a combination intervention for sustainable blood pressure control in rural KwaZulu-Natal, South Africa (IMPACT BP): A three-arm, unblinded, parallel group indivi	12
Functional outcomes of diets in multiple sclerosis (FOOD for MS): Protocol for a parallel arm randomized feeding trial for low glycemic load and calorie restriction	12
Results of a pilot study examining the effect of positive psychology interventions on cannabis use and related consequences	12
A two-stage Bayesian adaptive design for minimum effective dose (MinED)-based dosing-finding trials	11
Engaging smokers in research: Utility of Facebook in facilitating recruitment to a smoking cessation study	11
Yoga, aerobic and stretching exercise effects on neurocognition: Randomized controlled trial protocol	11
Clinic navigation and home visits to improve asthma care in low income adults with poorly controlled asthma: Before and during the pandemic	11
Intermittent fasting for systemic triglyceride metabolic reprogramming (IFAST): Design and methods of a prospective, randomized, controlled trial	11
Effect of the New Nordic Diet compared with usual care on glucose control in gestational diabetes mellitus: Study protocol for the randomized controlled trial intervention with new Nordic DIet in wome	11
Increasing the adoption of evidence-based communication practices for HPV vaccination in primary care clinics: The HPV ECHO study protocol for a cluster randomized controlled trial	11
Hub-and-Spoke centralized intervention to optimize colorectal cancer screening and follow-up: A pragmatic, cluster-randomized controlled trial protocol	11
The clinical and cost effectiveness of internet-delivered self-help Acceptance and Commitment Therapy for family carers of people with dementia (iACT4CARERS): Study protocol for a randomised controlle	11
Open Dialogue compared to treatment as usual for adults experiencing a mental health crisis: Protocol for the ODDESSI multi-site cluster randomised controlled trial	11
Strategies to improve the recruitment and retention of underserved children and families in clinical trials: A case example of a school-supervised asthma therapy pilot	10
Targeting white matter neuroprotection as a relapse prevention strategy for treatment of cocaine use disorder: Design of a mechanism-focused randomized clinical trial	10
Design of the FRESH-DOSE study: A randomized controlled noninferiority trial evaluating a guided self-help family-based treatment program for children with overweight or obesity	10
Project EPIC (Empowering People to Independence in COPD): Study protocol for a hybrid effectiveness-implementation pilot randomized controlled trial of telephonic, geriatrics-palliative care nurse-coa	10
Rationale and methodology for examining the combination of aerobic exercise and cognitive rehabilitation on new learning and memory in persons with multiple sclerosis and mobility disability: Protocol	10
Increasing goals of care conversations in primary care: Study protocol for a cluster randomized, pragmatic, sequential multiple assignment randomized trial	10
Protocol for a multicenter, double-blinded placebo-controlled randomized controlled trial comparing intravenous ferric derisomaltose to oral ferrous sulfate for the treatment of iron deficiency anemia	10
A parish-based multilevel cluster randomized controlled trial to reduce stigma and mental health treatment disparities among Latino communities	10
Promotion of Successful Weight Management in Overweight and Obese Veterans (POWER-VET): Trial Design and Methods	10
Financial incentives and case management to improve cardiac rehabilitation participation among patients with lower socio-economic status: Rationale and protocol for a randomized controlled trial	10
Lessons learned while starting multi-institutional genetics research in diverse populations: A report from the Clinical Sequencing Evidence-Generating Research (CSER) consortium	10
Toe-in and toe-out gait retraining interventions to reduce proxy measures of medial knee joint load in people with medial knee osteoarthritis: Protocol for a randomised placebo-controlled trial	10
Ultra-processed food intake, gut microbiome, and glucose homeostasis in mid-life adults: Background, design, and methods of a controlled feeding trial	10
MIRROR-TCM: Multisite Replication of a Randomized Controlled Trial - Transitional Care Model	10
The importance of methods for site performance evaluation in REPRIEVE, a longitudinal, global, multicenter trial	10
A nurse-delivered intervention to reduce insomnia in cancer survivors: Study protocol for a randomized-controlled trial	10
Design and methods of the StepByStep randomized trial of a mobile health and social media physical activity intervention among adolescent and young adult survivors of childhood cancer: A report from t	10
Food resources and kitchen skills plus aerobic training (FoRKS+) for black adults with hypertension: A pilot trial protocol	10
Fostering Inclusivity in Research Engagement for Underrepresented Populations in Parkinson's Disease: The FIRE-UP PD study	9
The Sit Less, Interact and Move More (SLIMM-2) Trial: Protocol for a randomized control trial of a sedentary behavior intervention, resistance training and semaglutide on sedentary behavior in persons	9
ROUTE-T1D: A behavioral intervention to promote optimal continuous glucose monitor use among racially minoritized youth with type 1 diabetes: Design and development	9
Acceptability of an intravaginal ring for simultaneously preventing HIV infection and pregnancy: Qualitative findings of the Kisumu Combined Ring Study, 2019	9
Central monitoring in a randomized, open-label, controlled phase 3 clinical trial for a treatment-shortening regimen for pulmonary tuberculosis	9
Effectiveness of a smoking cessation algorithm integrated into HIV primary care: Study protocol for a randomized controlled trial	9
Effect of nutritional guidance on employee work ability, work well-being and quality of life (RAVI trial): Study protocol for a randomized controlled trial	9
Ozanimod as a novel oral small molecule therapy for the treatment of Crohn's disease: The YELLOWSTONE clinical trial program	9
Family history and cancer risk study (FOREST): A clinical trial assessing electronic patient-directed family history input for identifying patients at risk of hereditary cancer	9
Testing Interventions for Mobility through Exercise (TIME): Study protocol for a randomized trial comparing a novel, brief home-based exercise program and a standard home-based group exercise for olde	9
The FALCON program: Two phase 2b randomized, double-blind, placebo-controlled studies to assess the efficacy and safety of pegbelfermin in the treatment of patients with nonalcoholic steatohepatitis a	9
Protocol for the implementation and referral of the ecofit physical activity intervention within Diabetes Alliance Program Plus among regional, rural and remote people with type 2 diabetes in a primar	9
Assessing attitudes towards pediatric research participation across diverse populations: Psychometric properties of a novel tool	9
Comparative effectiveness of trauma-focused and non-trauma-focused psychotherapy for PTSD among veterans with comorbid substance use disorders: Protocol & rationale for a randomized clinical trial	9
The next generation of collaborative care: The design of a novel web-based stepped collaborative care intervention delivered via telemedicine for people diagnosed with cancer	9
The protocol of the Application of Economics & Social psychology to improve Opioid Prescribing Safety Trial 1 (AESOPS-1): Electronic health record nudges	9
Evaluating the MyPath web-based reproductive decision support tool in VA primary care: Protocol for a pragmatic cluster randomized trial	9
A novel ‘social contract’ – An attempt to harmonize a sponsor's exploratory research with a clinical study participant's data rights	9
Increasing screening for breast cancer using a randomized evaluation of electronic health record nudges: Design and rationale of the I-screen clinical trial	9
Protocol of a randomized controlled trial into guided internet-delivered cognitive behavioral therapy for insomnia in autistic adults (i-Sleep Autism)	9
Testing an insurance-based monetary incentive program for exercise: RCT design and rationale	9
Study design and protocol for Nourishing Beginnings, an integrated service delivery model addressing food insecurity and social needs of low-income pregnant individuals	9
Distribution of age, sex, race, and ethnicity in COVID-19 clinical drug trials in the United States: A review	9
Rationale and design of a randomized controlled clinical trial; Titration of Oxygen Levels (TOOL) during mechanical ventilation	9
Design, methods, and recruitment outcomes of the Veterans' Pain Care Organizational Improvement Comparative Effectiveness (VOICE) study	9
A SMART approach to optimizing delivery of an mHealth intervention among cancer survivors with posttraumatic stress symptoms	8
Evaluating the evaluators - Developing evidence of quality oversight effectiveness for clinical trial monitoring: Source data verification, source data review, statistical monitoring, key risk indicat	8
Cognitive rehabilitation in post-COVID-19 condition: A study protocol for a randomized controlled trial	8
Study protocol: Behavioral economics and self-determination theory to change diabetes risk (BEST Change)	8
Remedy to Diabetes Distress (R2D2): Development protocol for a scalable screen-to-treat program for families of school-age children	8
Comparative effectiveness of biofeedback and injectable bulking agents for treatment of fecal incontinence: Design and methods	8
Modifying Diet and Exercise in MS (MoDEMS): Study design and protocol for a telehealth weight loss intervention for adults with obesity & Multiple Sclerosis	8
Testing a tailored weight management program for veterans with PTSD: The MOVE! + UP randomized controlled trial	8
STRategies to Improve Pain and Enjoy life (STRIPE): Protocol for a pragmatic randomized trial of pain coping skills training and opioid medication taper guidance for patients on long-term opioid thera	8
A randomized, controlled multicenter feasibility pilot trial on imaging confirmed uncomplicated acute appendicitis: Appendectomy vs. symptomatic treatment in pediatric patients (the APPSYPP) trial stu	8
One committee to review it all: A single, multi-disciplinary COVID-19 research committee	8
Rationale and protocol for a randomized waitlist controlled trial of videoconference delivered cognitive behaviour therapy for insomnia (CBT-I) to improve perceived cognitive impairment (PCI) among ca	8
Personalized antiplatelet therapy based on clopidogrel/aspirin resistance tests in acute ischemic stroke and transient ischemic attack: Study protocol of a multi-center, single-blinded and randomized	8
Two-sample survival probability curves: A graphical approach for the analysis of time to event data in clinical trials	8
Assessing the impact of medically tailored meals and medical nutrition therapy on type 2 diabetes: Protocol for Project MiNT	8
Bayesian EMAX model with a mixture of normal distributions for dose–response in clinical trials	8
Design of the Advancing Care for Type 1 Diabetes and Obesity Network energy metabolism and sequential multiple assignment randomized trial nutrition pilot studies: An integrated approach to develop we	8
Comparing the effectiveness of existing anxiety treatment options among patients evaluated for chest pain and anxiety in the emergency department setting: Study protocol for the PACER pragmatic random	8
Design of a randomized clinical trial of brief couple therapy for PTSD augmented with intranasal oxytocin	7

eHealth mindfulness-based music therapy for patients undergoing allogeneic hematopoietic stem cell transplantation: A pilot randomized controlled trial protocol	7
Design, rationale, and baseline characteristics of a randomized controlled trial evaluating a mobile relational agent to enhance atrial fibrillation self-care	7
Communication Coaching in Cardiology (CCC): A study protocol and methodological challenges and solutions of a randomized controlled trial in outpatient cardiology clinics	7
Design and methods of a randomized telehealth-based intervention to improve fitness in survivors of childhood cancer with exercise intolerance	7
Written exposure therapy for posttraumatic stress symptoms and suicide risk: Design and methodology of a randomized controlled trial with patients on a military psychiatric inpatient unit	7
Time-consuming and expensive data quality monitoring procedures persist in clinical trials: A national survey	7
Incorporating systems-level stakeholder perspectives into the clinical trial design of school-supervised asthma therapy	7
Executive control training for adolescents with ADHD: Study protocol for a randomised controlled trial	7
Smart Technology for Aging and Reducing Disability (STAReD): Study protocol for a randomized pragmatic clinical trial	7
Design of Behavioral Economic Applications to Geriatrics Leveraging Electronic Health Records (BEAGLE): A pragmatic cluster randomized controlled trial	7
Corrigendum to ‘Integrative data analysis of clinical trials network studies to examine the impact of psychosocial treatments for Black people who use cocaine: Study protocol’ [Contemporary Clinical T	7
An optimal two-stage exploratory basket trial design with aggregated futility analysis	7
Vida Sana y Completa: A randomized controlled trial to examine the effectiveness of diabetes prevention with and without medically supportive groceries among Latina women	7
Virtual versus usual in-office care for multiple sclerosis: The VIRTUAL-MS multi-site randomized clinical trial study protocol	7
Study protocol for a randomized, controlled trial using a novel, family-centered diet treatment to prevent nonalcoholic fatty liver disease in Hispanic children	7
Assessing the potential anti-neuroinflammatory effect of minocycline in chronic low back pain: Protocol for a randomized, double-blind, placebo-controlled trial	7
INERTIA: A pilot study of the impact of progressive resistance training on blood pressure control in older adults with sarcopenia	7
Biorepository best practices for research and clinical investigations	7
Safer Bars: A cluster-randomized effectiveness evaluation of alcohol-related sexual violence prevention through bar staff bystander training	7
Clinical research nurses' perceptions of the unique needs of people of color for successful recruitment to cancer clinical trials	7
Rationale and design of Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation (NAPT) Trial	7
Editorial Board	7
Controlled backfill in oncology dose-finding trials	6
BEhavioral Health Stratified Treatment (B.E.S.T.) to optimize transition to adulthood for youth with intellectual and/or developmental disabilities	6
A randomised controlled trial of a multidisciplinary TEAM-based approach to guide secondary cardiovascular risk reduction for patients with Peripheral Artery Disease (TEAM-PAD) study protocol	6
Enhancing clinical drug trial monitoring with blockchain technology	6
A protocol for a randomized controlled trial of exposure and response prevention for veterans with obsessive compulsive disorder	6
Design considerations and analytical framework for reliably identifying a beneficial individualized treatment rule	6
A high fiber diet intervention during pregnancy: The SPROUT (Single goal in PRegnancy to optimize OUTcomes) protocol paper	6
The electronic health record Risk of Alzheimer’s and Dementia Assessment Rule (eRADAR) Brain Health Trial: Protocol for an embedded, pragmatic clinical trial of a low-cost dementia detection algorithm	6
Design and baseline characteristics of participants in the COcoa Supplement and Multivitamin Outcomes Study (COSMOS)	6
Diversity, equity, and inclusion in clinical trials: A practical guide from the perspective of a trial sponsor	6
The Exercise aNd hEArt transplant (ENEA) trial – a registry-based randomized controlled trial evaluating the safety and efficacy of cardiac telerehabilitation after heart transplant	6
Oral human papillomavirus (HPV) and associated factors among healthy populations: The design of the PROGRESS (PRevalence of Oral hpv infection, a Global aSSessment) study	6
Platform trials to evaluate the benefit-risk of COVID-19 therapeutics: Successes, learnings, and recommendations for future pandemics	6
Controlled amplification in oncology dose-finding trials	6
Multi-site feasibility and fidelity of remote yoga intervention to improve management of type-2 diabetes: Design and methods of the HA1C (Healthy Active and In Control) study	6
Effectiveness of “run-ins” at predicting adherence in a behavioral weight loss efficacy trial	6
Implementing a randomised controlled trial through community pharmacies to support people living with severe and persistent mental illness: Lessons learnt during the COVID-19 pandemic	6
Design of a hybrid implementation effectiveness cluster randomized controlled trial of delivering written exposure therapy for PTSD in underserved primary care settings	6
Biofeedback EMG alternative therapy for chronic low back pain: Study protocol of a pilot randomized controlled trial	6
Enrollment of female participants in United States drug and device phase 1–3 clinical trials between 2016 and 2019	6
Imputation methods for informative censoring in survival analysis with time dependent covariates	6
Design and implementation of a cluster randomized trial measuring benefits of medical scribes in the VA	6
Rationale and design of a multisite randomized clinical trial examining an integrated behavioral treatment for veterans with co-occurring chronic pain and opioid use disorder: The pain and opioids int	6
A variation of a 2-in-1 adaptive design to seamlessly expand a selected dose from a phase 2 trial to a phase 3 trial for oncology drug development	6
Comparison of intravascular ultrasound-guided with optical coherence tomography-guided percutaneous coronary intervention for left main distal bifurcation lesions: Rationale and design of the ISOLEDS	6
An innovative protocol for the artificial speech-directed, contactless administration of laboratory-based comprehensive cognitive assessments: PAAD-2 trial management during the COVID-19 pandemic	6
Protocol for a randomized controlled trial of medically tailored meals compared to usual care among individuals with type 2 diabetes in Australia	6
Thank you to our Reviewers in 2024	6
A clinical trial protocol of a single-session self-guided acceptance-based online intervention targeting food cravings as predictors of disordered eating in pregnant people	6
The use of amantadine in the prevention of progression and treatment of COVID-19 symptoms in patients infected with the SARS-CoV-2 virus (COV-PREVENT): Study rationale and design	6
Development and evaluation of objective trial performance metrics for multisite clinical studies: Experience from the AlcHep Network	6
Protocol for a randomized controlled trial to evaluate the effectiveness of a telehealth group intervention to reduce perinatal depressive symptoms	5
Technical procedures and REDCap tools for internet-based clinical trials	5
I kua na'u "Let me carry out your last wishes" Clinical trial protocol to promote advance care planning among native Hawaiian populations	5
Preface to theme issue on pragmatic and virtual trials: Progress and challenges	5
A comprehensive open-source library for exact required sample size in binary clinical trials	5
Design of the Healthcare Worker Exposure Response and Outcomes (HERO) research platform	5
Practical considerations of promising zone design for interim sample size Re-estimation: An application to GRAPHITE for graft vs host disease	5
Omega-3 supplementation and heart failure: A meta-analysis of 12 trials including 81,364 participants	5
Study protocol for a sequential multiple assignment randomized trial to reduce risky drinking among service members and their partners	5
Data-dependent contrast test for dose-finding clinical trials	5
Hybrid 1 randomized controlled trial of an integrated stepped-care mental health intervention for traumatic injury patients	5
Promoting physical activity in young adult cancer survivors using mHealth and adaptive tailored feedback strategies: Design of the Improving Physical Activity after Cancer Treatment (IMPACT) randomize	5
Adherence rates during a randomized controlled trial evaluating the use of blinded acetaminophen and ibuprofen in children with asthma	5
The Bone, Exercise, Alendronate, and Caloric Restriction (BEACON) trial design and methods	5
A pragmatic randomized clinical trial of multilevel interventions to improve adherence to lung cancer screening (The Larch Study): Study protocol	5
Rationale and design of a randomized controlled clinical trial of a resilience-building intervention in adults with congenital heart disease	5
Selecting trial centers using a standardized, automated site assessment survey instrument (SASI)	5
Digital technologies and the democratization of clinical research: Social media, wearables, and artificial intelligence	5
Guest Editors' introduction to the 15th anniversary special issue	5
Optimizing remote access to urinary incontinence treatments for women veterans (PRACTICAL): Study protocol for a pragmatic clinical trial comparing two virtual care options	5
Protocol for a randomized clinical trial for Avoidant Restrictive Food Intake Disorder (ARFID) in low-weight youth	5
DEcrease STress through RESilience training for Students (DESTRESS) Study: Protocol for a randomized controlled trial nested in a longitudinal observational cohort study	5
Internet-delivered lifestyle physical activity intervention for cognitive processing speed in multiple sclerosis	5
Care ally-assisted massage for Veterans with chronic neck pain: TOMCATT results	5
The comparative effectiveness of COVID-19 monoclonal antibodies: A learning health system randomized clinical trial	5
Randomized controlled trial of the ehavioral ntervention for increasing hysical ctivity in ultiple clerosis project: Secondary, patient-reported outcomes	5
Overcoming challenges in conducting early phase breast cancer prevention trials: Bazedoxifene and conjugated estrogens vs waitlist control	5
Statistical analysis plan for the NU IMPACT stepped-wedge cluster randomized trial	5
Methods to characterize lactate turnover in aging and Alzheimer's disease; The LEAN study	5
Improving multimodal physical function in adults with heterogeneous chronic pain; Protocol for a multisite feasibility RCT	5
Impact of COVID-19 pandemic on oncology clinical trial design, data collection and analysis	5
Editorial Board	5
Design and rationale for a randomized clinical trial testing the efficacy of a lifestyle physical activity intervention for people with HIV and engaged in unhealthy drinking	5
Study protocol and rationale for a randomized, placebo-controlled trial of solriamfetol to treat binge eating disorder	5
STEP-Home transdiagnostic group reintegration workshop to improve mental health outcomes for post-9/11 Veterans: Design, methods, and rationale for a randomized controlled behavioral trial	5
Effects of transcranial direct current stimulation on balance after ischemic stroke (SANDE trial): Study protocol for a multicentric randomized controlled trial	5
Recruitment patterns in multicentre randomised trials fit more closely to Price's Law than the Pareto Principle: A review of trials funded and published by the United Kingdom Health Technology Assessm	5
Effectiveness of a pharmacist-delivered primary care telemedicine intervention to increase access to pharmacotherapy and specialty treatment for alcohol use problems: Protocol for the alcohol telemedi	5
Strategies to optimize inclusion of women in multi-national clinical trials	5
A study design for statistical learning technique to predict radiological progression with an application of idiopathic pulmonary fibrosis using chest CT images	5
Improving racial disparities in unmet palliative care needs among intensive care unit family members with a needs-targeted app intervention: The ICUconnect randomized clinical trial	5
Implementing changing behaviour towards aerobic and strength exercise: Results of a randomised, phase I study determining the safety, feasibility, and consumer-evaluation of an online exercise program	5