OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Pathology-Mechanisms of Disease is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis	470
B Cell Responses to the Placenta and Fetus	373
Reflections on a Career in Pediatric Neuropathology, with a Note of Gratitude	247
Apolipoprotein E and Alzheimer's Disease: Findings, Hypotheses, and Potential Mechanisms	243
	218
RNA Damage Responses in Cellular Homeostasis, Genome Stability, and Disease	193
Cystic Fibrosis and the Cells of the Airway Epithelium: What Are Ionocytes and What Do They Do?	177
Recent Advances in Understanding of Pathogenesis of Alcohol-Associated Liver Disease	161
Circadian Clocks, Daily Stress, and Neurodegenerative Disease	159
Pathogenesis of Triple-Negative Breast Cancer	126
	122
Tuft Cells: Context- and Tissue-Specific Programming for a Conserved Cell Lineage	106
Neuroepithelial Interactions in Cancer	105
Pathogenesis of Germinal Matrix Hemorrhage: Insights from Single-Cell Transcriptomics	99
Engineering β Cell Replacement Therapies for Type 1 Diabetes: Biomaterial Advances and Considerations for Macroscale Constructs	98
Tumor-Derived Extracellular Vesicles: Multifunctional Entities in the Tumor Microenvironment	93
Immune Dysregulation in Obesity	91
Neutrophils in Physiology and Pathology	88
The Immune Response in Multiple Sclerosis	81
Pathogenesis of Focal Segmental Glomerulosclerosis and Related Disorders	72
The Immunobiology and Pathogenesis of Celiac Disease	72
My Journey	70
After the Storm: Regeneration, Repair, and Reestablishment of Homeostasis Between the Alveolar Epithelium and Innate Immune System Following Viral Lung Injury	67
Molecular Pathology of Laminopathies	63
Cancer as a Disease of Development Gone Awry	62

ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency	61
Genetics and Pathogenesis of Dystonia	60
	57
Somatic Mosaicism in Brain Disorders	55
DNA Methylation Profiling: An Emerging Paradigm for Cancer Diagnosis	52
Role of Fungi in Tumorigenesis: Promises and Challenges	51
The Pathogenesis of African Trypanosomiasis	50
Hypoxia-Induced Signaling in Gut and Liver Pathobiology	50
Multiplexed Ion Beam Imaging: Insights into Pathobiology	47
Inherited Predispositions to Myeloid Neoplasms: Pathogenesis and Clinical Implications	45
Within-Host Evolution of Bacterial Pathogens in Acute and Chronic Infection	44
Metabolism and Colorectal Cancer	43
Innate Immunity and Cancer Pathophysiology	42
Haploinsufficient Transcription Factors in Myeloid Neoplasms	37
Polycystic Liver Disease: Advances in Understanding and Treatment	37
Unraveling Mechanisms of Genetic Risks in Metabolic Dysfunction–Associated Steatotic Liver Diseases: A Pathway to Precision Medicine	30
Cutaneous Squamous Cell Carcinoma: The Frontier of Cancer Immunoprevention	29
Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance	29
Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology	27
Targeting Protein–Protein Interactions in Hematologic Malignancies	25
Genome Instability and DNA Repair in Somatic and Reproductive Aging	24
Choroid Plexus Pathophysiology	24