OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Pathology-Mechanisms of Disease is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Immunopathology of Glioblastoma	529
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis	430
Reflections on a Career in Pediatric Neuropathology, with a Note of Gratitude	294
B Cell Responses to the Placenta and Fetus	279
Apolipoprotein E and Alzheimer's Disease: Findings, Hypotheses, and Potential Mechanisms	246
	204
Role of Chromatin Looping Factors in Leukemia	192
Cystic Fibrosis and the Cells of the Airway Epithelium: What Are Ionocytes and What Do They Do?	187
RNA Damage Responses in Cellular Homeostasis, Genome Stability, and Disease	175
Recent Advances in Understanding of Pathogenesis of Alcohol-Associated Liver Disease	143
Circadian Clocks, Daily Stress, and Neurodegenerative Disease	138
Clonal Hematopoiesis in Nonmalignant Disease: Functional Consequences of Mutated Immune Cells by Clonal Hematopoiesis in the Diseased Tissue	126
Pathogenesis of Triple-Negative Breast Cancer	122
	115
Tuft Cells: Context- and Tissue-Specific Programming for a Conserved Cell Lineage	109
Pathology of the Coronary Arteries and Myocardium in Kawasaki Disease	106
Neuroepithelial Interactions in Cancer	105
Molecular Subtypes of Neuroendocrine Carcinoma: From Chaos to Consensus	98
Engineering β Cell Replacement Therapies for Type 1 Diabetes: Biomaterial Advances and Considerations for Macroscale Constructs	95
Neutrophils in Physiology and Pathology	83
Molecular Pathogenesis of Uterine Sarcomas: Mechanisms and Implications for Treatment	79
Pathogenesis of Germinal Matrix Hemorrhage: Insights from Single-Cell Transcriptomics	78
Immune Dysregulation in Obesity	77
The Role of MicroRNAs in Viral and Bacterial Infections	73
Tumor-Derived Extracellular Vesicles: Multifunctional Entities in the Tumor Microenvironment	73

Pathogenesis of Focal Segmental Glomerulosclerosis and Related Disorders	70
The Immune Response in Multiple Sclerosis	67
The Immunobiology and Pathogenesis of Celiac Disease	65
My Journey	63
After the Storm: Regeneration, Repair, and Reestablishment of Homeostasis Between the Alveolar Epithelium and Innate Immune System Following Viral Lung Injury	62
The Role of Fibroblasts Across Inflammation and Immunity	61
Molecular Pathology of Laminopathies	60
Genetics and Pathogenesis of Dystonia	59
Cancer as a Disease of Development Gone Awry	56
	55
ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency	55
Somatic Mosaicism in Brain Disorders	50
DNA Methylation Profiling: An Emerging Paradigm for Cancer Diagnosis	48
Role of Fungi in Tumorigenesis: Promises and Challenges	46
Multiplexed Ion Beam Imaging: Insights into Pathobiology	41
The Pathogenesis of African Trypanosomiasis	38
Hypoxia-Induced Signaling in Gut and Liver Pathobiology	37
Exploring the Complex Pathophysiology of Necrotizing Enterocolitis in Preterm Neonates	35
Inherited Predispositions to Myeloid Neoplasms: Pathogenesis and Clinical Implications	33
Within-Host Evolution of Bacterial Pathogens in Acute and Chronic Infection	29
Metabolism and Colorectal Cancer	28
Polycystic Liver Disease: Advances in Understanding and Treatment	27
Innate Immunity and Cancer Pathophysiology	26
Haploinsufficient Transcription Factors in Myeloid Neoplasms	26
Unraveling Mechanisms of Genetic Risks in Metabolic Dysfunction–Associated Steatotic Liver Diseases: A Pathway to Precision Medicine	25
Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology	23
Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance	23
Cutaneous Squamous Cell Carcinoma: The Frontier of Cancer Immunoprevention	22
Precision Medicine in Low- and Middle-Income Countries	22