OOIR: Observatory of International Research

Papers

(The median citation count of Annual Review of Pathology-Mechanisms of Disease is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis	425
Reflections on a Career in Pediatric Neuropathology, with a Note of Gratitude	341
B Cell Responses to the Placenta and Fetus	219
Apolipoprotein E and Alzheimer's Disease: Findings, Hypotheses, and Potential Mechanisms	211
	206
RNA Damage Responses in Cellular Homeostasis, Genome Stability, and Disease	181
Cystic Fibrosis and the Cells of the Airway Epithelium: What Are Ionocytes and What Do They Do?	166
Recent Advances in Understanding of Pathogenesis of Alcohol-Associated Liver Disease	152
Circadian Clocks, Daily Stress, and Neurodegenerative Disease	149
	112
Pathogenesis of Triple-Negative Breast Cancer	112
Tuft Cells: Context- and Tissue-Specific Programming for a Conserved Cell Lineage	98
Neuroepithelial Interactions in Cancer	95
Pathogenesis of Germinal Matrix Hemorrhage: Insights from Single-Cell Transcriptomics	89
Immune Dysregulation in Obesity	88
Neutrophils in Physiology and Pathology	82
Engineering β Cell Replacement Therapies for Type 1 Diabetes: Biomaterial Advances and Considerations for Macroscale Constructs	82
Tumor-Derived Extracellular Vesicles: Multifunctional Entities in the Tumor Microenvironment	81
Pathogenesis of Focal Segmental Glomerulosclerosis and Related Disorders	68
The Immunobiology and Pathogenesis of Celiac Disease	63
The Immune Response in Multiple Sclerosis	62
My Journey	58
After the Storm: Regeneration, Repair, and Reestablishment of Homeostasis Between the Alveolar Epithelium and Innate Immune System Following Viral Lung Injury	57
Molecular Pathology of Laminopathies	56
ENPP1 in Blood and Bone: Skeletal and Soft Tissue Diseases Induced by ENPP1 Deficiency	55

Cancer as a Disease of Development Gone Awry	54
Genetics and Pathogenesis of Dystonia	54
	52
Somatic Mosaicism in Brain Disorders	46
Role of Fungi in Tumorigenesis: Promises and Challenges	46
DNA Methylation Profiling: An Emerging Paradigm for Cancer Diagnosis	46
Hypoxia-Induced Signaling in Gut and Liver Pathobiology	44
Multiplexed Ion Beam Imaging: Insights into Pathobiology	44
Inherited Predispositions to Myeloid Neoplasms: Pathogenesis and Clinical Implications	41
The Pathogenesis of African Trypanosomiasis	41
Polycystic Liver Disease: Advances in Understanding and Treatment	38
Within-Host Evolution of Bacterial Pathogens in Acute and Chronic Infection	36
Metabolism and Colorectal Cancer	33
Haploinsufficient Transcription Factors in Myeloid Neoplasms	32
Innate Immunity and Cancer Pathophysiology	32
Unraveling Mechanisms of Genetic Risks in Metabolic Dysfunction–Associated Steatotic Liver Diseases: A Pathway to Precision Medicine	27
Cutaneous Squamous Cell Carcinoma: The Frontier of Cancer Immunoprevention	25
Choroid Plexus Pathophysiology	24
Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic Resistance	24
Precision Medicine in Low- and Middle-Income Countries	24
Spatiotemporal Metabolic Liver Zonation and Consequences on Pathophysiology	24