Autophagy

Papers
(The TQCC of Autophagy is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)11413
Ferroptosis: machinery and regulation785
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells172
Mitophagy in degenerative joint diseases156
Mitochondria ROS and mitophagy in acute kidney injury151
Inhibiting NLRP3 inflammasome attenuates apoptosis in contrast-induced acute kidney injury through the upregulation of HIF1A and BNIP3-mediated mitophagy148
How autophagy controls the intestinal epithelial barrier134
The ménage à trois of autophagy, lipid droplets and liver disease121
Tumor heterogeneity in autophagy-dependent ferroptosis116
Coronavirus interactions with the cellular autophagy machinery108
Autophagy in ovary and polycystic ovary syndrome: role, dispute and future perspective107
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activation106
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons97
Keratinocyte autophagy enables the activation of keratinocytes and fibroblastsand facilitates wound healing96
Autophagy in the physiological endometrium and cancer96
Copper-dependent autophagic degradation of GPX4 drives ferroptosis93
PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damage92
New insights regarding SNARE proteins in autophagosome-lysosome fusion90
Full-coverage regulations of autophagy by ROS: from induction to maturation88
Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells87
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV485
MAPK1/3 kinase-dependent ULK1 degradation attenuates mitophagy and promotes breast cancer bone metastasis85
HIF1A Alleviates compression-induced apoptosis of nucleus pulposus derived stem cells via upregulating autophagy84
Regulation of PRKN-independent mitophagy80
Acetylation in the regulation of autophagy80
AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE379
Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway77
TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation77
BNIP3L/NIX degradation leads to mitophagy deficiency in ischemic brains76
Targeting autophagy in disease: established and new strategies76
Regulation and function of autophagy in pancreatic cancer74
m6A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin72
Copper metabolism in cell death and autophagy72
Manipulation of autophagy by SARS-CoV-2 proteins67
Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5)67
Autophagy and ALS: mechanistic insights and therapeutic implications67
Selective autophagy regulates heat stress memory in Arabidopsis by NBR1-mediated targeting of HSP90.1 and ROF166
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells66
Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB)66
ATF4 links ER stress with reticulophagy in glioblastoma cells65
The role of mitophagy in the regulation of mitochondrial energetic status in neurons65
Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice64
SIRT1 – a new mammalian substrate of nuclear autophagy62
Hydrogen peroxide mediates spermidine-induced autophagy to alleviate salt stress in cucumber62
FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway62
Autophagy in age-related macular degeneration62
Selective autophagy controls the stability of transcription factor IRF3 to balance type I interferon production and immune suppression60
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress60
Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion60
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB60
Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP359
Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence59
CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression59
SMAD3 promotes autophagy dysregulation by triggering lysosome depletion in tubular epithelial cells in diabetic nephropathy56
BNIP3L/Nix-induced mitochondrial fission, mitophagy, and impaired myocyte glucose uptake are abrogated by PRKA/PKA phosphorylation55
The multifaceted regulation of mitophagy by endogenous metabolites55
Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice54
Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response54
CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellul54
Chloroquine combined with concurrent radiotherapy and temozolomide for newly diagnosed glioblastoma: a phase IB trial54
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective53
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells53
C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels52
Photodynamic therapy: autophagy and mitophagy, apoptosis and paraptosis51
Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine51
DCN released from ferroptotic cells ignites AGER-dependent immune responses51
Alternative mitochondrial quality control mediated by extracellular release51
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer51
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor50
Vitamin D-VDR (vitamin D receptor) regulates defective autophagy in renal tubular epithelial cell in streptozotocin-induced diabetic mice via the AMPK pathway50
BHRF1, a BCL2 viral homolog, disturbs mitochondrial dynamics and stimulates mitophagy to dampen type I IFN induction49
The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication49
GPX4 in cell death, autophagy, and disease49
Selective autophagy of MHC-I promotes immune evasion of pancreatic cancer48
Selective autophagy receptor SQSTM1/ p62 inhibits Seneca Valley virus replication by targeting viral VP1 and VP347
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis47
MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma47
HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway46
Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic pain46
The influence of circular RNAs on autophagy and disease progression46
Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2R1441Gmice46
TMEM164 is a new determinant of autophagy-dependent ferroptosis45
USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP345
Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis45
Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway45
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy44
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD44
Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders44
The role of autophagy in targeted therapy for acute myeloid leukemia44
Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs43
Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway42
AMPK protects against alcohol-induced liver injury through UQCRC2 to up-regulate mitophagy42
Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT140
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes40
Emerging views of OPTN (optineurin) function in the autophagic process associated with disease39
Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction39
Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death38
CGAS is a micronucleophagy receptor for the clearance of micronuclei38
M. tuberculosis PknG manipulates host autophagy flux to promote pathogen intracellular survival38
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycle37
RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging37
Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein37
Augmenting ATG14 alleviates atherosclerosis and inhibits inflammation via promotion of autophagosome-lysosome fusion in macrophages37
Eicosapentaenoic acid attenuates renal lipotoxicity by restoring autophagic flux37
LUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG1336
Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy36
Rapamycin relieves the cataract caused by ablation of Gja8b through stimulating autophagy in zebrafish36
LDHB inhibition induces mitophagy and facilitates the progression of CSFV infection36
ESRRA (estrogen related receptor alpha) is a critical regulator of intestinal homeostasis through activation of autophagic flux via gut microbiota36
Vitamin D3-VDR-PTPN6 axis mediated autophagy contributes to the inhibition of macrophage foam cell formation35
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation35
Exploring the role of non-coding RNAs in autophagy34
Autophagy and post-ischemic conditioning in retinal ischemia34
Phosphorylation of ATG18a by BAK1 suppresses autophagy and attenuates plant resistance against necrotrophic pathogens34
Macrophage mitochondrial MFN2 (mitofusin 2) links immune stress and immune response through reactive oxygen species (ROS) production34
Muscle-generated BDNF (brain derived neurotrophic factor) maintains mitochondrial quality control in female mice33
ATM loss disrupts the autophagy-lysosomal pathway33
An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles33
Piperine promotes autophagy flux by P2RX4 activation in SNCA /α-synuclein-induced Parkinson disease model32
Degradation of the NOTCH intracellular domain by elevated autophagy in osteoblasts promotes osteoblast differentiation and alleviates osteoporosis32
Phosphoregulation of the autophagy machinery by kinases and phosphatases32
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation32
Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging32
The role of autophagy in bone metabolism and clinical significance31
Autophagy in metabolism and quality control: opposing, complementary or interlinked functions?31
ATI1 (ATG8-interacting protein 1) and ATI2 define a plant starvation-induced reticulophagy pathway and serve as MSBP1/MAPR5 cargo receptors31
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx31
A VASt-domain protein regulates autophagy, membrane tension, and sterol homeostasis in rice blast fungus31
LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization31
Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability30
Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy30
Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples30
Mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC29
BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver29
GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions29
Protective effect of the tunneling nanotube-TNFAIP2/M-sec system on podocyte autophagy in diabetic nephropathy29
HFE inhibits type I IFNs signaling by targeting the SQSTM1-mediated MAVS autophagic degradation29
ATF3 -activated accelerating effect of LINC00941/lncIAPF on fibroblast-to-myofibroblast differentiation by blocking autophagy depending on ELAVL1/HuR in pulmonary fibrosis29
The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in shaping immune responses and host defense during infection29
Inhibition of PLA2G4E/cPLA2 promotes survival of random skin flaps by alleviating Lysosomal membrane permeabilization-Induced necroptosis28
CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response28
Targeting glutamine metabolism and autophagy: the combination for prostate cancer radiosensitization28
Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage28
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels27
AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system27
Regulation of autophagy by DNA G-quadruplexes27
CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux27
Two different axes CALCOCO2-RB1CC1 and OPTN-ATG9A initiate PRKN-mediated mitophagy27
Analysis of Drosophila Atg8 proteins reveals multiple lipidation-independent roles27
1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation27
Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability26
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions26
Negative pressure wound therapy improves bone regeneration by promoting osteogenic differentiation via the AMPK-ULK1-autophagy axis26
Mir214-3p and Hnf4a/Hnf4α reciprocally regulate Ulk1 expression and autophagy in nonalcoholic hepatic steatosis26
Autophagy coupled to translation is required for long-term memory26
Autophagy/virophagy: a “disposal strategy” to combat COVID-1926
Regulation and repurposing of nutrient sensing and autophagy in innate immunity26
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy25
Extracellular SQSTM1 as an inflammatory mediator25
Autophagic lysosome reformation in health and disease25
PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1)25
A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence25
HPV sensitizes OPSCC cells to cisplatin-induced apoptosis by inhibiting autophagy through E7-mediated degradation of AMBRA125
BLOC1S1/GCN5L1/BORCS1 is a critical mediator for the initiation of autolysosomal tubulation25
PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery25
AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability25
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology25
Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytes25
LC3 subfamily in cardiolipin-mediated mitophagy: a comparison of the LC3A, LC3B and LC3C homologs24
SARS-CoV-2 ORF3a induces RETREG1/FAM134B-dependent reticulophagy and triggers sequential ER stress and inflammatory responses during SARS-CoV-2 infection24
LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells24
Glutamine, MTOR and autophagy: a multiconnection relationship24
AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability24
C53 is a cross-kingdom conserved reticulophagy receptor that bridges the gap betweenselective autophagy and ribosome stalling at the endoplasmic reticulum24
WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms24
Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease24
The DNA methyltransferase DNMT3A contributes to autophagy long-term memory23
Lighting up the fire in cold tumors to improve cancer immunotherapy by blocking the activity of the autophagy-related protein PIK3C3/VPS3423
LGALS3 (galectin 3) mediates an unconventional secretion of SNCA/α-synuclein in response to lysosomal membrane damage by the autophagic-lysosomal pathway in human midbrain dopamine neurons23
Lipotoxicity reduces DDX58/Rig-1 expression and activity leading to impaired autophagy and cell death23
Membrane dynamics and protein targets of lipid droplet microautophagy during ER stress-induced proteostasis in the budding yeast, Saccharomyces cerevisiae23
Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner23
Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?23
ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation22
PRCC-TFE3 fusion-mediated PRKN/parkin-dependent mitophagy promotes cell survival and proliferation in PRCC-TFE3 translocation renal cell carcinoma22
OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity22
Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis22
Chaperone-mediated autophagy controls the turnover of E3 ubiquitin ligase MARCHF5 and regulates mitochondrial dynamics22
Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways22
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy22
The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy22
TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss22
USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy22
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation22
GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex22
WDR45, one gene associated with multiple neurodevelopmental disorders22
Celastrol, a TFEB (transcription factor EB) agonist, is a promising drug candidate for Alzheimer disease22
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA421
Vac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy21
Outer membrane vesicles produced by pathogenic strains of Escherichia coli block autophagic flux and exacerbate inflammasome activation21
Measurement of autophagic flux in humans: an optimized method for blood samples21
Identification of an autoinhibitory, mitophagy-inducing peptide derived from the transmembrane domain of USP3021
Atg21 organizes Atg8 lipidation at the contact of the vacuole with the phagophore21
RETREG1/FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual organellar turnover mechanism21
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine21
Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease21
Autophagy in farm animals: current knowledge and future challenges21
Coxsackievirus B3 targets TFEB to disrupt lysosomal function21
Quantitative proteomic analysis of temporal lysosomal proteome and the impact of the KFERQ-like motif and LAMP2A in lysosomal targeting21
2AB protein of Senecavirus A antagonizes selective autophagy and type I interferon production by degrading LC3 and MARCHF821
Regulation of oxidative stress-induced autophagy by ATG9A ubiquitination21
FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination21
TOR and MAP kinase pathways synergistically regulate autophagy in response to nutrient depletion in fission yeast21
Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy20
An inverted CAV1 (caveolin 1) topology defines novel autophagy-dependent exosome secretion from prostate cancer cells20
LRRK2 is required for CD38-mediated NAADP-Ca2+signaling and the downstream activation of TFEB (transcription factor EB) in immune cells20
Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis20
STING1 is essential for an RNA-virus triggered autophagy20
The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy20
PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes20
PKD2/polycystin-2 induces autophagy by forming a complex with BECN120
Mitophagy coordination with retrograde transport ensures the integrity of synaptic mitochondria20
Protein complexes and neighborhoods driving autophagy20
MLKL contributes to Western diet-induced liver injury through inhibiting autophagy20
Neutrophils use selective autophagy receptor Sqstm1/p62 to target Staphylococcus aureus for degradation in vivo in zebrafish20
Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis20
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease19
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death19
The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males19
Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancer19
Involvement of autophagy in exacerbation of eosinophilic airway inflammation in a murine model of obese asthma19
RAB33B recruits the ATG16L1 complex to the phagophore via a noncanonical RAB binding protein19
A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers19
Genome-Scale CRISPR screen identifies LAPTM5 driving lenvatinib resistance in hepatocellular carcinoma19
Differential activation of eMI by distinct forms of cellular stress19
Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models19
Retromer regulates the lysosomal clearance of MAPT/tau19
TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation19
Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis19
MERIT, a cellular system coordinating lysosomal repair, removal and replacement19
Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy19
The chaperone-assisted selective autophagy complex dynamics and dysfunctions19
Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules19
TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins19
Garcinia cambogia attenuates adipogenesis by affecting CEBPB and SQSTM1/p62-mediated selective autophagic degradation of KLF3 through RPS6KA1 and STAT3 suppression18
Autophagic degradation of CCN2 (cellular communication network factor 2) causes cardiotoxicity of sunitinib18
UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation18
Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice18
Rice black-streaked dwarf virus P10 promotes phosphorylation of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) to induce autophagy in Laodelphax striatellus18
Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation18
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