OOIR: Observatory of International Research

Papers

(The TQCC of ACS Chemical Biology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Probing the Binding Mechanism of Acylated Peptides to Human Serum Albumin	191
Issue Editorial Masthead	97
Screening a Molecular Fragment Library to Modulate the PED/PEA15-Phospholipase D1 Interaction in Cellular Lysate Environments	94
Simple Enzymatic Incorporation of 2′OMeU Nucleotide at the End of the Poly-A Tail for Enhancement of the mRNA Stability and Protein Expression	81
Brominated Carbazole with Antibiotic Adjuvant Activity Displays Pleiotropic Effects in MRSA’s Transcriptome	73
Intramolecular H-Atom Transfers in Alkoxyl Radical Intermediates Underlie the Apparent Oxidation of Lipid Hydroperoxides by Fe(II)	71
Ferroptosis Inhibitors Suppress Prostaglandin Synthesis in Lipopolysaccharide-Stimulated Macrophages	69
Issue Editorial Masthead	61
HiBiT-SpyTag: A Minimal Tag for Covalent Protein Capture and Degrader Development	57
Chemical Scaffolds for the Clinical Development of Mutant-Selective and Reversible Fourth-Generation EGFR-TKIs in NSCLC	57
Correction to “Dimensionally Enhanced Antibacterial Library Screening”	53
Introducing Our Authors	49
Introducing Our Authors	48
Introducing Our Authors	47
Issue Editorial Masthead	47
Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with Candida albicans	44
Mapping Sphingolipid Metabolism Pathways during Phagosomal Maturation	43
Direct Nanopore Sequencing for the 17 RNA Modification Types in 36 Locations in the E. coli Ribosome Enables Monitoring of Stress-Dependent Changes	43
Functional Redundancy and Dual Function of a Hypothetical Protein in the Biosynthesis of Eunicellane-Type Diterpenoids	41
Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists	41
Issue Publication Information	40
Exponential Combination of a and e/g Intracellular Peptide Libraries Identifies a Selective ATF3 Inhibitor	40
Introducing Our Authors	40
Introducing Our Authors	40
Issue Publication Information	39

Issue Publication Information	38
Introducing Our Authors	38
Issue Editorial Masthead	38
Issue Editorial Masthead	37
Issue Publication Information	36
Merits of Diazirine Photo-Immobilization for Target Profiling of Natural Products and Cofactors	36
Introducing Our Authors	36
Correction to Bifunctional Cytochrome P450 Enzymes Involved in Camptothecin Biosynthesis	36
Introducing Our Authors	36
The SARS-CoV-2 Programmed −1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 Å Using Chaperone-Assisted RNA Crystallography	35
Chemoenzymatic Synthesis of Novel Cytotoxic Epoxyketones Using the Eponemycin Biosynthetic Enzyme EpnF	34
Issue Publication Information	33
Issue Editorial Masthead	33
Introducing Our Authors	33
Issue Publication Information	33
Multi-TACs: Targeting Solid Tumors with Multiple Immune Cell Co-engagers	32
Effect of pH-Responsive Ligands on mRNA Knockdown in EGFR-Targeting Ligand-Conjugated siRNAs	32
Dynamic Regulation of 5-Formylcytidine on tRNA	32
Transcriptomics-Driven Discovery of New Meroterpenoid Rhynchospenes Involved in the Virulence of the Barley Pathogen Rhynchosporium commune	32
In Vitro Characterization of an O-Specific Glycosyltransferase Involved in Flagellin Glycosylation	31
Correction to “Structure and Biosynthesis of Hectoramide B, a Linear Depsipeptide from Marine Cyanobacterium Moorena producens JHB Discovered via Coculture with Candida albicans”	31
Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit	30
Understanding and Circumventing the Requirement for Native Thioester Substrates for α-Oxoamine Synthase Reactions	30
Issue Editorial Masthead	29
In Situ Labeling of Pathogenic Tau Using Photo-Affinity Chemical Probes	29
European Robin Cryptochrome-4a Associates with Lipid Bilayers in an Ordered Manner, Fulfilling a Molecular-Level Condition for Magnetoreception	28
Modulating Copper Reactivity: A New Approach to Reprogram Mitochondrial Retrograde Signaling	27
Convergent Biocatalytic Mediated Synthesis of siRNA	27
Identification and Benchmarking of Myokinasib-II as a Selective and Potent Chemical Probe for Exploring MLCK1 Inhibition	27
Algal Kainoid Synthases Exhibit Substrate-Dependent Hydroxylation and Cyclization Activities	26
Accelerating the Validation of Endogenous On-Target Engagement and In Cellulo Kinetic Assessment for Covalent Inhibitors of KRAS^G12C in Early Drug Discovery	25
Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions	25
Identification of DDX5 as a Potential Therapeutic Target of Osteosarcoma Using Thiazolone Probes	25
Proteolytic Regulation in the Biosynthesis of Natural Product Via a ClpP Protease System	24
Heterologous Expression Facilitates the Production and Characterization of a Class III Lanthipeptide with Coupled Labionin Cross-Links in Sponge-Associated Streptomyces rochei MB037	24
Extrapolating Lessons from Targeted Protein Degradation to Other Proximity-Inducing Drugs	24
Unveiling a Potent Small Molecule Disruptor for RNA G-Quadruplexes Tougher Than DNA G-Quadruplex Disruption	24
Discovery of Antinociceptive α9α10 Nicotinic Acetylcholine Receptor Antagonists by Stable Receptor Expression	23
Endogenous Enzymes Enable Antimicrobial Activity	23
Parallel Screening Using the Chloroalkane Penetration Assay Reveals Structure-Penetration Relationships	23
Bioorthogonal Cyclopropenones for Investigating RNA Structure	23
Structure Prediction and Protein Engineering Yield New Insights into Microcin J25 Precursor Recognition	23
Single-Cell Multiomics Identifies Glycan Epitope LacNAc as a Potential Cell-Surface Effector Marker of Peripheral T Cells in Bladder Cancer Patients	23
Characterization of a Dual Function Peptide Cyclase in Graspetide Biosynthesis	23
Identification of Aberrant Expression of Gemcitabine-Targeting Proteins in Drug-Resistant Cells Using an Activity-Based Gemcitabine Probe	23
Interspecies Crosstalk via LuxI/LuxR-Type Quorum Sensing Pathways Contributes to Decreased Nematode Survival in Coinfections of Pseudomonas aeruginosa and Burkholderia multivorans	23
Molecular Targeted Engagement of DPP9 in Rat Tissue Using CETSA, SP3 Processing, and Absolute Quantitation Mass Spectrometry	23
Heterologous Catalysis of the Final Steps of Tetracycline Biosynthesis by Saccharomyces cerevisiae	23
Synthesis of 3-O-Sulfated Heparan Sulfate Oligosaccharides Using 3-O-Sulfotransferase Isoform 4	22
In-Cell Penetration Selection–Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery	22

Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools	22
Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells	22
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome	22
Charge Assisted S/Se Chalcogen Bonds in SAM Riboswitches: A Combined PDB and ab Initio Study	22
Synthetic Multivalent Disulfide-Constrained Peptide Agonists Potentiate Wnt1/β-Catenin Signaling via LRP6 Coreceptor Clustering	22
Membrane-Bound Flavocytochrome MsrQ Is a Substrate of the Flavin Reductase Fre in Escherichia coli	22
Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding	21
Robust Chemoenzymatic Synthesis of Keratinimicin Aglycone Analogues Facilitated by the Structure and Selectivity of OxyB	21
Ynamide Coupling Reagent for the Chemical Cross-Linking of Proteins in Live Cells	21
Engineered Glycan-Binding Proteins for Recognition of the Thomsen–Friedenreich Antigen and Structurally Related Disaccharides	21
Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase	21
Synthesis of Gamma-Butyrolactone Hormones Enables Understanding of Natural Product Induction	21
Key Amino Acid Residues of Mitochondrial Transcription Factor A Synergize with Abasic (AP) Site Dynamics To Facilitate AP-Lyase Reactions	21
HSP27 Inhibitory Activity against Caspase-3 Cleavage and Activation by Caspase-9 Is Enhanced by Chaperone O-GlcNAc Modification in Vitro	21
Photoswitchable Inhibitors to Optically Control Specific Kinase Activity	21
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments	21
Correction to “The Antibacterial Synnepyrroles from Human-associated Nocardiopsis sp. Show Protonophore Activity and Disrupt the Bacterial Cytoplasmic Membrane”	21
Optimization of a Protein-Targeted Medicine into an RNA-Specific Small Molecule	20
Maramycin, a Cytotoxic Isoquinolinequinone Terpenoid Produced through Heterologous Expression of a Bifunctional Indole Prenyltransferase/Tryptophan Indole-Lyase in S. albidoflavus	20
Visualization of Ectopic Serine Protease Activity by Förster Resonance Energy Transfer-Based Reporters	20
RNA-Binding Peptides Inspired by the RNA Recognition Motif	20
Effect of the Phosphoryl Guanidine Modification in Chimeric DNA–RNA crRNAs on the Activity of the CRISPR-Cas9 System In Vitro	20
Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages	20
An Inherent Difference between Serine and Threonine Phosphorylation: Phosphothreonine Strongly Prefers a Highly Ordered, Compact, Cyclic Conformation	20
Structural Basis of Amide-Forming Adenylation Enzyme VinM in Vicenistatin Biosynthesis	20
A Robust α-l-Fucosidase from Prevotella nigrescens for Glycoengineering Therapeutic Antibodies	20
Targeting and Manipulating Tryptophan Interactions on Proteins	20
Forward Genetic Screens Identify Mechanisms of Resistance to Small-Molecule Lactate Dehydrogenase Inhibitors	20
A Chemical Counterpart to the Resolution Step of Nature’s Intein-Mediated Protein Splicing	20
Revealing Drivers for Carboxy-S-adenosyl-l-methionine Use by Neomorphic Variants of a DNA Methyltransferase	20
Bioluminescent Intercalating Dyes for Ratiometric Nucleic Acid Detection	20
A C-Degron Structure-Based Approach for the Development of Ligands Targeting the E3 Ligase TRIM7	20
Metabolic Investigation and Auxiliary Enzyme Modelization of the Pyrrocidine Pathway Allow Rationalization of Paracyclophane-Decahydrofluorene Formation	20
Targeting Ribonucleases with Small Molecules and Bifunctional Molecules	20
Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues	19
Tandem Chemoimmunotherapy by a Cascade-Responsive Molecular Prodrug	19
Comprehensive Mutational Analysis of the Lasso Peptide Klebsidin	19
Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2	19
Structural and Biophysical Analysis of the Phytochelatin-Synthase-Like Enzyme from Nostoc sp. Shows That Its Protease Activity is Sensitive to the Redox State of the Substrate	18
Biologically Derived Neoproteoglycans for Profiling Protein–Glycosaminoglycan Interactions	18
Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism	18
Screen for Small-Molecule Modulators of Circadian Rhythms Reveals Phenazine as a Redox-State Modifying Clockwork Tuner	18
Identification and Biosynthesis of Pro-Inflammatory Sulfonolipids from an Opportunistic Pathogen Chryseobacterium gleum	18
Glyco-Nanoadjuvants: Impact of Linker Length for Conjugating a Synthetic Small-Molecule TLR7 Ligand to Glyco-Nanoparticles on Immunostimulatory Effects	18
Identification of Gut Bacterial Enzymes for Keto-Reductive Metabolism of Xenobiotics	18
A Chemical Biology Perspective to Therapeutic Regulation of RNA Splicing in Spinal Muscular Atrophy (SMA)	18
Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer	18
A Protein Semisynthesis-Based Strategy to Investigate the Functional Impact of Linker Histone Serine ADP-Ribosylation	18
Directing CAR NK Cells via the Metabolic Incorporation of CAR Ligands into Malignant Cell Glycans	18
Spatiotemporal Proximity Labeling Tools to Track GlcNAc Sugar-Modified Functional Protein Hubs during Cellular Signaling	18
A Nonfunctional Halogenase Masquerades as an Aromatizing Dehydratase in Biosynthesis of Pyrrolic Polyketides by Type I Polyketide Synthases	17
Enzymatic Macrolactamization of mRNA Display Libraries for Inhibitor Selection	17
A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures	17
Immunogenicity Evaluation of N-Glycans Recognized by HIV Broadly Neutralizing Antibodies	17
Multiassay Profiling of a Focused Small Molecule Library Reveals Predictive Bidirectional Modulation of the lncRNA MALAT1 Triplex Stability In Vitro	17
Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth	17
A Designer Nanoparticle Platform for Controlled Intracellular Delivery of Bioactive Macromolecules: Inhibition of Ubiquitin-Specific Protease 7 in Breast Cancer Cells	17
Mechanistic Studies on Dehydration in Class V Lanthipeptides	17
Synthetic Natural Product Inspired Cyclic Peptides	17
Importance of the Cyclic Cystine Knot Structural Motif for Immunosuppressive Effects of Cyclotides	17
Unraveling the Photoactivation Mechanism of a Light-Activated Adenylyl Cyclase Using Ultrafast Spectroscopy Coupled with Unnatural Amino Acid Mutagenesis	17
Time-Dependent Studies of Oxaliplatin and Other Nucleolar Stress-Inducing Pt(II) Derivatives	17
¹⁹F-NMR Unveils the Ligand-Induced Conformation of a Catalytically Inactive Twisted Homodimer of tRNA–Guanine Transglycosylase	17
Celastrol Targets Cullin-Associated and Neddylation-Dissociated 1 to Prevent Fibroblast–Myofibroblast Transformation against Pulmonary Fibrosis	17
Visualizing an Allosteric Intermediate Using CuAAC Stabilization of an NMR Mixed Labeled Dimer	17
Elucidating the Role and Structure–Activity Relationships of the Streptococcus oligofermentans Competence-Stimulating Peptide	17
Generating Efficient Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetases for Structurally Diverse Non-Canonical Amino Acids	17
Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k	17
Phosphorothioate-Based Site-Specific Labeling of Large RNAs for Structural and Dynamic Studies	17
Targeted Degradation of mRNA Decapping Enzyme DcpS by a VHL-Recruiting PROTAC	17
Quantitative Chemoproteomic Profiling of Protein Cross-Links Induced by Methylglyoxal	17
Bioinformatic Searching for Optimal RNA Targets of Dimeric Compounds Informs Design of a MicroRNA-27a Inhibitor	16
In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A	16
Visible Light Control over the Cytolytic Activity of a Toxic Pore-Forming Protein	16
Genetically Encoded Benzoyllysines Serve as Versatile Probes for Interrogating Histone Benzoylation and Interactions in Living Cells	16
First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy	16
β-Methyltryptamine Provoking the Crucial Role of Strictosidine Synthase Tyr151-OH for Its Stereoselective Pictet−Spengler Reactions to Tryptoline-type Alkaloids	16
Sustainable B₁₂-Dependent Dehalogenation of Organohalides in E. coli	16
Discovery of 2,6-Dihalopurines as Stomata Opening Inhibitors: Implication of an LRX-Mediated H⁺-ATPase Phosphorylation Pathway	16
Mechanistic Insights into Harmine-Mediated Inhibition of Human DNA Methyltransferases and Prostate Cancer Cell Growth	16

Discovery of Non-Cysteine-Targeting Covalent Inhibitors by Activity-Based Proteomic Screening with a Cysteine-Reactive Probe	16
Differential Biosynthesis and Roles of Two Ferrichrome-Type Siderophores, ASP2397/AS2488053 and Ferricrocin, in Acremonium persicinum	16
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling	16
Improving Split Reporters of Protein–Protein Interactions through Orthology-Based Protein Engineering	16
Structural Characterization of Degrader-Induced Ternary Complexes Using Hydrogen–Deuterium Exchange Mass Spectrometry and Computational Modeling: Implications for Structure-Based Design	16
Rational Design of Chemically Controlled Antibodies and Protein Therapeutics	16
Confounding Factors in Targeted Degradation of Short-Lived Proteins	15
Structure and Energetics of GTP- and GDP-Tubulin Isodesmic Self-Association	15
Cell-surface Labeling via Bioorthogonal Host–Guest Chemistry	15
Targeting IRAK3 for Degradation to Enhance IL-12 Pro-inflammatory Cytokine Production	15
High-Resolution Substrate Specificity Profiling of SARS-CoV-2 M^pro; Comparison to SARS-CoV M^pro	15
Synthesis of Differentially Halogenated Lissoclimide Analogues To Probe Ribosome E-Site Binding	15
Pharmacological Advantage of SIRT2-Selective versus pan-SIRT1–3 Inhibitors	15
LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis	15
Direct Cysteine Desulfurase Activity Determination by NMR and the Study of the Functional Role of Key Structural Elements of Human NFS1	15
Reengineering of Circularly Permuted Caspase-2 to Enhance Enzyme Stability and Enable Crystallographic Studies	15
Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity	14
Bioactive Compounds of Arthrospira spp. (Spirulina) with Potential Anticancer Activities: A Systematic Review	14
Identification, Heterologous Expression, and Characterization of the Tolypodiol Biosynthetic Gene Cluster through an Integrated Approach	14
Isonitrile-Tetrazine Click-and-Release Chemistry for Controlling RNA-Guided Nucleic Acid Cleavage	14
Formation of the i-motif Structures by Human Telomeric c-Rich Sequences d(CCCTAA)n and Its Recognition by Bisbenzylisoquinoline Alkaloids	14
Substrate Promiscuity of the Triceptide Maturase XncB Leads to Incorporation of Various Amino Acids and Detection of Oxygenated Products	14
Biodistributions of l,d-Transpeptidases in Gut Microbiota Revealed by In Vivo Labeling with Peptidoglycan Analogs	14
Fragment-Based Phenotypic Lead Discovery To Identify New Drug Seeds That Target Infectious Diseases	14
Click Chemistry Methodology: The Novel Paintbrush of Drug Design	14
Expanding the Substrate Selectivity of the Fimsbactin Biosynthetic Adenylation Domain, FbsH	14
Antimicrobial Lasso Peptide Cloacaenodin Utilizes a Unique TonB-Dependent Transporter to Access Susceptible Bacteria	14
Spontaneous Cleavage at Glu and Gln Residues in Long-Lived Proteins	14
Structural and Biochemical Insights into Lignin-Oxidizing Activity of Bacterial Peroxidases against Soluble Substrates and Kraft Lignin	14
Call for Papers: Exploring Covalent Modulators in Drug Discovery and Chemical Biology	13
Christopher T. Walsh: A Prolific Scientist, Effective Academic Leader, and Responsive Mentor	13
Introducing Our Authors	13
ACS Chemical Biology─2022 Editorial Statement	13
Go to the Board: A Journey through the Life of Professor David A. Evans	13
PUFA-Derived N-Acylethanolamide Probes Identify Peroxiredoxins and Small GTPases as Molecular Targets in LPS-Stimulated RAW264.7 Macrophages	13
Issue Publication Information	13
Introducing Our Authors	13
Issue Editorial Masthead	13
Issue Publication Information	13
Introducing Our Authors	13
Issue Editorial Masthead	13
Issue Publication Information	13
New Account Articles to Support and Promote the Next Generation of Leaders in Chemical Biology	13
Thermorubin Biosynthesis Initiated by a Salicylate Synthase Suggests an Unusual Conversion of Phenols to Pyrones	13
Issue Editorial Masthead	13
Bioorthogonal Monomycolate of Trehalose Disclosed the O-Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in C. glutamicum	13
Issue Editorial Masthead	13
Introducing Our Authors	13
On the Question of CO’s Ability to Induce HO-1 Expression in Cell Culture: A Comparative Study Using Different CO Sources	13
Covalent Catalytic Strategies for Enzymes That Modify RNA Molecules on their Tripartite Building Blocks	13
Chemical Proteomics Reveals Off-Targets of the Anandamide Reuptake Inhibitor WOBE437	12
Issue Editorial Masthead	12
Issue Publication Information	12
Issue Editorial Masthead	12
2-Cyanopyrimidine-Containing Molecules for N-Terminal Selective Cyclization of Phage-Displayed Peptides	12
A Comparison of Two Stability Proteomics Methods for Drug Target Identification in OnePot 2D Format	12
Opening New Avenues in Bioorganic Chemistry: Prof. Chuan He Receives the Tetrahedron Prize	12
Issue Publication Information	12
YTHDF3 Facilitates eIF2AK2 and eIF3A Recruitment on mRNAs to Regulate Translational Processes in Oxaliplatin-Resistant Colorectal Cancer	12
Introducing Our Authors	12
Issue Editorial Masthead	12
Issue Publication Information	12
Issue Editorial Masthead	12
Structural and Mechanistic Characterization of the Flavin-Dependent Monooxygenase and Oxidase Involved in Sorbicillinoid Biosynthesis	12
Characterization of RufT Thioesterase Domain Reveals Insights into Rufomycin Cyclization and the Biosynthetic Origin of Rufomyazine	12
Outer Membrane Vesicle-Mediated Codelivery of the Antifungal HSAF Metabolites and Lytic Polysaccharide Monooxygenase in the Predatory Lysobacter enzymogenes	12
Prokaryotic RNA N1-Methyladenosine Erasers Maintain tRNA m1A Modification Levels in Streptomyces venezuelae	12
Issue Editorial Masthead	12
Issue Editorial Masthead	12
Issue Editorial Masthead	12
Issue Publication Information	12
Structure of the Outer Membrane Transporter FemA and Its Role in the Uptake of Ferric Dihydro-Aeruginoic Acid and Ferric Aeruginoic Acid in Pseudomonas aeruginosa	12
Introducing Our Authors	12
Antibacterial Marinopyrroles and Pseudilins Act as Protonophores	12
The Chemical Synthesis of Knob Domain Antibody Fragments	12
Issue Publication Information	12
N-Acyl-N-Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A_2B Receptor as Case Study	12
Bright Red Bioluminescence from Semisynthetic NanoLuc (sNLuc)	11
Workflow for E3 Ligase Ligand Validation for PROTAC Development	11
Multiplex, Quantitative, High-Resolution Imaging of Protein:Protein Complexes via Hybridization Chain Reaction	11
Enhanced EphB2-Specific Peptide Inhibitors through Stabilization of Polyproline II Helical Structure	11
Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization	11
Analysis of the Valgamicin Biosynthetic Pathway Reveals a General Mechanism for Cyclopropanol Formation across Diverse Natural Product Scaffolds	11
Trifunctional Sphinganine: A New Tool to Dissect Sphingolipid Function	11
Covalent Targeting As a Common Mechanism for Inhibiting NLRP3 Inflammasome Assembly	11
Characterization, Structure, and Inhibition of the Human Succinyl-CoA:glutarate-CoA Transferase, a Putative Genetic Modifier of Glutaric Aciduria Type 1	11
Engineering a Low-Immunogenic Mirror-Image VHH against Vascular Endothelial Growth Factor	11
Lanmodulin’s EF 2–3 Domain: Insights from Infrared Spectroscopy and Simulations	11
Roles of Nucleic Acids in Protein Folding, Aggregation, and Disease	11
Laboratory Evolution of Metalloid Reductase Substrate Recognition and Nanoparticle Product Size	11
A Humanized Mouse Model Coupled with Computational Analysis Identifies Potent Glycolipid Agonist of Invariant NKT Cells	11
Targeting the Main Protease (M^pro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies	11
Phospholipids Differentially Regulate Ca²⁺ Binding to Synaptotagmin-1	11
Light-Inducible Activation of TrkA for Probing Chronic Pain in Mice	11
Chemical Genetics in C. elegans Identifies Anticancer Mycotoxins Chaetocin and Chetomin as Potent Inducers of a Nuclear Metal Homeostasis Response	11