Epigenetics

Article	Citations
GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis	81
Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns	60
Epigenetic landscape of 5-hydroxymethylcytosine and associations with gene expression in placenta	35
N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells	35
Using methylation data to improve transcription factor binding prediction	31
Co-occurrence of injection drug use and hepatitis C increases epigenetic age acceleration that contributes to all-cause mortality among people living with HIV	29
Transcriptional signature of cardiac myocyte recovery in mice and human reveals persistent upregulation of epigenetic factors	27
Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells	25
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	25
Differential methylation patterns in cord blood associated with prenatal exposure to neighborhood crime: an epigenome-wide association study and regional analysis	25
Role of N6-methyladenosine-related lncRnas in pseudoexfoliation glaucoma	24
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	23
Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche	23
Mechanism of crosstalk between DNA methylation and histone acetylation and related advances in diagnosis and treatment of premature ovarian failure	22
Multiomics analysis of adaptation to repeated DNA damage in prostate cancer cells	21
Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution	21
Detailed immune profiling in pediatric Crohn’s disease using methylation cytometry	21
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	20
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway	20
The influence of intergenerational trauma on epigenetics and obesity in Indigenous populations - a scoping review	20
Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH) 2 D in adipocytes	20
Integrative DNA methylation and transcriptome analysis reveal cell-type specific patterns in response to elevated allostatic load	19
Chromatin structural gene expression stratifies cardiac cell populations in health and disease	19
Placental malaria induces a unique methylation profile associated with fetal growth restriction	19
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia	18

Accelerated epigenetic age at birth and child emotional and behavioural development in early childhood: a meta-analysis of four prospective cohort studies in ECHO	18
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	17
Epigenome-wide association study of loneliness in a sample of U.S. middle-aged twins	17
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells	16
Mendelian randomization analysis of CpG methylation and immune phenotypes in epithelial ovarian cancer outcomes	16
Identification cloning and functional analysis of novel natural antisense lncRNA CFL1-AS1 in cattle	16
Acetaldehyde-driven mRNA methylation and expression changes in ethanol-metabolizing enzyme genes	16
Genomic context determines the effect of DNA methylation on gene expression in the gut epithelium of Atlantic salmon ( Salmo salar )	15
ACMSD methylation in peripheral blood is associated with dynamic functional connectivity pattern in adolescent MDD patients	15
Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva in the Fragile Families and Child Wellbeing cohort	15
Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data	15
Pan-precancer and cancer DNA methylation profiles revealed significant tissue specificity of interrupted biological processes in tumorigenesis	15
Placental and immune cell DNA methylation reference panel for bulk tissue cell composition estimation in epidemiological studies	15
PIK3R1 and G0S2 are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation	15
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	14
Regulatory networks of circRNA- centred ceRNAs in sepsis-induced acute kidney injury	14
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	14
ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer	14
Integration of miRNA expression analysis of purified leukocytes and whole blood reveals blood-borne candidate biomarkers for lung cancer	14
CpG island demethylation and recruitment of SP1 to the promoter region regulates human thymic stromal lymphopoietin expression	14
Blood DNA methylation signatures are associated with social determinants of health among survivors of childhood cancer	14
CircRIMKLB promotes myoblast proliferation and inhibits differentiation by sponging miR-29c to release KCNJ12	14
Upregulation of KHDC1L promotes the proliferation and inhibits apoptosis in head and neck squamous cell carcinoma	14
Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancer	13
Comprehensive analysis of m 6 A methylomes in idiopathic pulmonary arterial hypertension	13
Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants	13
Cut&tag: a powerful epigenetic tool for chromatin profiling	13
The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo[a]pyrene exposed F1 and F3 male medaka	13
Changes in nuclear and mitochondrial DNA methylation in cow blood associated with age and disease	13
Large-scale integration of DNA methylation and gene expression array platforms identifies both cis and trans relationships	13
Timing of dietary effects on the epigenome and their potential protective effects against toxins	13
The one-carbon metabolism as an underlying pathway for placental DNA methylation – a systematic review	13
Tributyltin chloride alters the structural, genomic, and epigenomic integrity of postejaculatory mammalian sperm	13
The role of histone methyltransferases in therapeutic resistance of NSCLC	13
Research progress on the mechanism of tumor cell ferroptosis regulation by epigenetics	12
Hypomethylation at H19DMR in penile squamous cell carcinoma is not related to HPV infection	12
Study on chromatin regulation patterns of expression vectors in the PhiC31 integration site	12
DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells	12
DNA-based cell typing in menstrual effluent identifies cell type variation by sample collection method: toward noninvasive biomarker development for women’s health	12
Heavy alcohol consumption but not smoking predicts mortality in patients with acute coronary syndrome	12
DNA methylation profiles in bovine sperm are associated with daughter fertility	12
RNA modification m 6 Am: the role in cardiac biology	12
Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes	12
Upregulation of GPR133 expression impaired the phagocytosis of macrophages in recurrent spontaneous miscarriage	12
Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use	12
mir152hypomethylation as a mechanism for non-syndromic cleft lip and palate	12
ΔNp63α-mediated epigenetic regulation in keratinocyte senescence	12
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	11
Gaps in current methods to detect polymorphic CpGs from Illumina Infinium human methylation microarrays and exploring their potential impact in multi-EWAS analyses	11
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress	11

Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes	11
Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial	11
DNA methylation at birth and fine motor ability in childhood: an epigenome-wide association study with replication	11
Epigenetic age acceleration, neonatal morbidities, and neurobehavioral profiles in infants born very preterm	11
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage	11
Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children	11
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis	11
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration	11
Insight into the mechanisms and dysregulation of KMT5C-H4K20me3 in cancer	10
Detection of DNA methylation from buccal swabs using nanopore sequencing to study stunting	10
Comparative genomic analyses reveal evidence for adaptive A-to-I RNA editing in insect Adar gene	10
Uncertainty quantification of reference-based cellular deconvolution algorithms	10
Time-course full profiling of circulating miRNAs in neurologically deceased organ donors: a proof of concept study to understand the onset of the cytokine storm	10
Precise epigenomic editing with a SunTag-based modular epigenetic toolkit	10
Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss	10
Methylome profile of medaka eggs and sperm	10
Domain architecture and protein–protein interactions regulate KDM5A recruitment to the chromatin	10
Advancements in DNA methylation technologies and their application in cancer diagnosis	10
Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene	10
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 express	10
Decitabine-induced DNA methylation remodeling reveals targetable biological processes in gilthead seabream pituitary and liver explants	10
DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target	10
A novel principal component based method for identifying differentially methylated regions in Illumina Infinium MethylationEPIC BeadChip data	10
Prenatal Socioeconomic Disadvantage and Epigenetic Alterations at Birth Among Children Born to White British and Pakistani Mothers in the Born in Bradford Study	10
Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression	10
Stress-induced epigenetic effects driven by maternal lactation in dairy cattle: a comethylation network approach	10
History of exposure to copper influences transgenerational gene expression responses in Daphnia magna	9
Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging	9
Genome-wide methylation analysis in patients with proximal hypospadias – a pilot study and review of the literature	9
Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation	9
m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	9
Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types	9
Comprehensive analysis of transcriptome‐wide M 6 A methylation for hepatic ischaemia reperfusion injury in mice	9
Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer	9
Epigenome-wide meta-analysis of prenatal vitamin D insufficiency and cord blood DNA methylation	9
Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth	9
Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinoma	9
Glucocorticoid receptor epigenetic activity in the heart	9
The multifaceted role of lactate in cardiovascular health: from metabolism to signaling and epigenetics	9
Epigenetic targeting of transposon relics: beating the dead horses of the genome?	9
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	9
Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure	9
Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows	9
Parental arsenic exposure and tissue-specific DNA methylation in Bangladeshi infants with spina bifida	9
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss	9
DNA hypermethylation of CADM1, PAX5, WT1, RARβ, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus	8
Implementation of the Methyl-Seq platform to identify tissue- and sex-specific DNA methylation differences in the rat epigenome	8
Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome	8
A cell type enrichment analysis tool for brain DNA methylation data (CEAM)	8
Fumonisin B 1 induces global DNA hypermethylation in human glioblastoma U87MG cells	8
MK-801-exposure induces increased translation efficiency and mRNA hyperacetylation of Grin2a in the mouse prefrontal cortex	8
Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome	8
Silencing of optogenetic and chemogenetic transgenes in human iPSCs involves promoter methylation and methylation-independent mechanisms	8
Imprinted gene alterations in the kidneys of growth restricted offspring may be mediated by a long non-coding RNA	8
Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes	8
Combined exercise training decreases blood pressure in OLDER women with NOS3 polymorphism providing changes in differentially methylated regions (DMRs)	8
Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors	8
IL21R hypomethylation as a biomarker for distinguishing benign and malignant breast tumours	7
Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium	7
Vitamin C enhances co-localization of novel TET1 nuclear bodies with both Cajal and PML bodies in colorectal cancer cells	7
Chimpanzee Extraversion scores vary with epigenetic modification of dopamine receptor gene D2 (DRD2) and early rearing conditions	7
Resistance and aerobic training increases genome-wide DNA methylation in women with polycystic ovary syndrome	7
Correction	7
In vivo DNA methylation editing in zebrafish	7
Identification of differentially methylated genes for severe acne by genome-wide DNA methylation and gene expression analysis	7
A promising application of kidney-specific cell-free DNA methylation markers in real-time monitoring sepsis-induced acute kidney injury	7
Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis	7
In silico identification and in vitro expression analysis of breast cancer-related m6A-SNPs	7
Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays	7
Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet	7
Epigenome-wide association study of long-term psychosocial stress in older adults	7
Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance)	7
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	7
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	6
m 6 A RNA methylation regulators predict prognosis and indicate characteristics of tumour microenvironment infiltration in acute myeloid leukaemia	6
YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway	6
Aberrant regulation of CXCR4 in cancer via deviant microRNA-targeted interactions	6
Circ-0006332 stimulates cardiomyocyte pyroptosis via the miR-143/TLR2 axis to promote doxorubicin-induced cardiac damage	6
Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus	6
Homocysteine affects macrophage polarization by altering m6A methylation of scavenger receptors CD209 and CD163L1	6

Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells	6
A qualitative prognostic biomarker for melanoma based on the relative methylation orderings of CpG loci	6
Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees	6
Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability s	6
Evaluating the utility of ZNF331 promoter methylation as a prognostic and predictive marker in stage III colon cancer: results from CALGB 89803 (Alliance)	6
Pruning and thresholding approach for methylation risk scores in multi-ancestry populations	6
Chromatin accessibility profiling of Treg cells in acute urticaria	6
Non-coding 886 ( nc886 / vtRNA2-1 ), the epigenetic odd duck – implications for future studies	6
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations	6
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues	5
DNA hypomethylation mediates immune response in pan-cancer	5
Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa	5
Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study	5
Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress	5
DNA methylation heterogeneity attributable to a complex tumor immune microenvironment prompts prognostic risk in glioma	5
Associations of green and blue space exposure in pregnancy with epigenetic gestational age acceleration	5
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part II – the impact of lactation rank	5
Comparison between indicine and taurine cattle DNA methylation reveals epigenetic variation associated to differences in morphological adaptive traits	5
Exploration of genome-wide DNA methylation profiles in night shift workers	5
Epigenetic editing of BRCA1 promoter increases cisplatin and olaparib sensitivity of ovarian cancer cells	5
LncRNA SCARNA8 promotes atherosclerotic plaque instability by inhibiting macrophage efferocytosis	5
Sex-specific DNA methylation in saliva from the multi-ethnic Future of Families and Child Wellbeing Study	5
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part I – the impact of inflammation	5
Phenotypic and transcriptomic impact of expressing mammalian TET2 in theDrosophila melanogastermodel	5
Strength of evidence for paternal influence on offspring epigenome in observational human studies: a systematic review and risk-of-bias appraisal for non-randomized exposures	5
MIMOSA: a resource consisting of improved methylome prediction models increases power to identify DNA methylation-phenotype associations	5
FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner	5