Epigenetics

Article	Citations
Disentangling tumorigenesis-associated DNA methylation changes in colorectal tissues from those associated with ageing	66
Digital methylation assessments of alcohol and cigarette consumption account for common variance in accelerated epigenetic ageing	45
Using methylation data to improve transcription factor binding prediction	32
Role of N6-methyladenosine-related lncRnas in pseudoexfoliation glaucoma	31
Transcriptional signature of cardiac myocyte recovery in mice and human reveals persistent upregulation of epigenetic factors	28
Co-occurrence of injection drug use and hepatitis C increases epigenetic age acceleration that contributes to all-cause mortality among people living with HIV	25
Differential methylation patterns in cord blood associated with prenatal exposure to neighborhood crime: an epigenome-wide association study and regional analysis	25
Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns	23
N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells	22
Epigenetic landscape of 5-hydroxymethylcytosine and associations with gene expression in placenta	22
GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis	20
Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells	20
Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens	19
Mechanism of crosstalk between DNA methylation and histone acetylation and related advances in diagnosis and treatment of premature ovarian failure	19
Placental DNA methylation in pregnancies complicated by maternal diabetes and/or obesity: State of the art and research gaps	19
Placental malaria induces a unique methylation profile associated with fetal growth restriction	18
Multiomics analysis of adaptation to repeated DNA damage in prostate cancer cells	18
Detailed immune profiling in pediatric Crohn’s disease using methylation cytometry	18
Proposal of a bioinformatics approach to predict molecular mechanisms involved in inflammatory response: case of ATRA and 1,25(OH) 2 D in adipocytes	18
The influence of intergenerational trauma on epigenetics and obesity in Indigenous populations - a scoping review	18
CircRNF111 Contributes to Adipocyte Differentiation by Elevating PPARγ Expression via miR-27a-3p	17
A novel lncRNA, Lnc21q22.11, suppresses gastric cancer growth by inhibiting MEK/ERK pathway	17
Generational stability of epigenetic transgenerational inheritance facilitates adaptation and evolution	17
Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche	17
MYCN and HIF-1 directly regulate TET1 expression to control 5-hmC gains and enhance neuroblastoma cell migration in hypoxia	16

Mendelian randomization analysis of CpG methylation and immune phenotypes in epithelial ovarian cancer outcomes	16
Epigenome-wide association study of loneliness in a sample of U.S. middle-aged twins	16
Identification cloning and functional analysis of novel natural antisense lncRNA CFL1-AS1 in cattle	15
Identification and characterization of extrachromosomal circular DNA in patients with high myopia and cataract	15
Pan-precancer and cancer DNA methylation profiles revealed significant tissue specificity of interrupted biological processes in tumorigenesis	15
Acetaldehyde-driven mRNA methylation and expression changes in ethanol-metabolizing enzyme genes	15
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA	15
Genomic context determines the effect of DNA methylation on gene expression in the gut epithelium of Atlantic salmon ( Salmo salar )	15
The UHRF1 protein is a key regulator of retrotransposable elements and innate immune response to viral RNA in human cells	15
Accelerated epigenetic age at birth and child emotional and behavioural development in early childhood: a meta-analysis of four prospective cohort studies in ECHO	15
Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva in the Fragile Families and Child Wellbeing cohort	15
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	14
Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data	14
PIK3R1 and G0S2 are human placenta-specific imprinted genes associated with germline-inherited maternal DNA methylation	14
Regulatory networks of circRNA- centred ceRNAs in sepsis-induced acute kidney injury	14
Placental and immune cell DNA methylation reference panel for bulk tissue cell composition estimation in epidemiological studies	14
Blood DNA methylation signatures are associated with social determinants of health among survivors of childhood cancer	13
Comprehensive analysis of m 6 A methylomes in idiopathic pulmonary arterial hypertension	13
ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer	13
Upregulation of KHDC1L promotes the proliferation and inhibits apoptosis in head and neck squamous cell carcinoma	13
Direct bisulphite conversion of cervical samples for DNA methylation analysis	13
Selenium-associated differentially expressed microRNAs and their targeted mRNAs across the placental genome in two U.S. birth cohorts	13
The role of histone methyltransferases in therapeutic resistance of NSCLC	13
Timing of dietary effects on the epigenome and their potential protective effects against toxins	13
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples	12
The role of DNA methylation on gene expression in the vertebrae of ancestrally benzo[a]pyrene exposed F1 and F3 male medaka	12
Large-scale integration of DNA methylation and gene expression array platforms identifies both cis and trans relationships	12
Chemotherapy-induced acceleration of DNA methylation-based biological age in breast cancer	12
The one-carbon metabolism as an underlying pathway for placental DNA methylation – a systematic review	12
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	12
Integration of miRNA expression analysis of purified leukocytes and whole blood reveals blood-borne candidate biomarkers for lung cancer	12
Cumulative stress, PTSD, and emotion dysregulation during pregnancy and epigenetic age acceleration in Hispanic mothers and their newborn infants	12
CpG island demethylation and recruitment of SP1 to the promoter region regulates human thymic stromal lymphopoietin expression	12
CircRIMKLB promotes myoblast proliferation and inhibits differentiation by sponging miR-29c to release KCNJ12	12
DNMT1 expression partially dictates 5-Azacytidine sensitivity and correlates with RAS/MEK/ERK activity in gastric cancer cells	11
Biological stability of DNA methylation measurements over varying intervals of time and in the presence of acute stress	11
Gaps in current methods to detect polymorphic CpGs from Illumina Infinium human methylation microarrays and exploring their potential impact in multi-EWAS analyses	11
DNA methylation profiles in bovine sperm are associated with daughter fertility	11
Cut&tag: a powerful epigenetic tool for chromatin profiling	11
ΔNp63α-mediated epigenetic regulation in keratinocyte senescence	11
Research progress on the mechanism of tumor cell ferroptosis regulation by epigenetics	11
Detecting aberrant DNA methylation in Illumina DNA methylation arrays: a toolbox and recommendations for its use	11
DNA-based cell typing in menstrual effluent identifies cell type variation by sample collection method: toward noninvasive biomarker development for women’s health	11
Study on chromatin regulation patterns of expression vectors in the PhiC31 integration site	11
Upregulation of GPR133 expression impaired the phagocytosis of macrophages in recurrent spontaneous miscarriage	10
Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis	10
DNA methylation at birth and fine motor ability in childhood: an epigenome-wide association study with replication	10
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	10
Heavy alcohol consumption but not smoking predicts mortality in patients with acute coronary syndrome	10
Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial	10

RNA modification m 6 Am: the role in cardiac biology	10
Alterations in DNA methylation associate with fatty liver and metabolic abnormalities in a multi-ethnic cohort of pre-teenage children	10
Hypomethylation at H19DMR in penile squamous cell carcinoma is not related to HPV infection	10
mir152hypomethylation as a mechanism for non-syndromic cleft lip and palate	10
Analysis of global DNA methylation and epigenetic modifiers (DNMTs and HDACs) in human foetal endothelium exposed to gestational and type 2 diabetes	10
Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients	10
Epigenetic age acceleration, neonatal morbidities, and neurobehavioral profiles in infants born very preterm	9
Detection of DNA methylation from buccal swabs using nanopore sequencing to study stunting	9
Prenatal Socioeconomic Disadvantage and Epigenetic Alterations at Birth Among Children Born to White British and Pakistani Mothers in the Born in Bradford Study	9
Methylome profile of medaka eggs and sperm	9
Oleic acid-related anti-inflammatory effects in force-stressed PdL fibroblasts are mediated by H3 lysine acetylation associated with altered IL10 expression	9
Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes	9
Higher sperm H3K4me3 levels are associated with idiopathic recurrent pregnancy loss	9
m6A reader YTHDC2 mediates NCOA4 mRNA stability affecting ferritinophagy to alleviate secondary injury after intracerebral haemorrhage	9
DNA methylation and bronchiectasis: a Mendelian randomization analysis to investigate causal link and therapeutic target	9
Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis	9
Comparative genomic analyses reveal evidence for adaptive A-to-I RNA editing in insect Adar gene	9
Domain architecture and protein–protein interactions regulate KDM5A recruitment to the chromatin	9
NSUN2-mediated RNA m5C modification modulates uveal melanoma cell proliferation and migration	9
Advancements in DNA methylation technologies and their application in cancer diagnosis	9
A novel principal component based method for identifying differentially methylated regions in Illumina Infinium MethylationEPIC BeadChip data	9
Sirtuin1 in vascular endothelial function, an overview	9
Uncertainty quantification of reference-based cellular deconvolution algorithms	9
Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse	8
History of exposure to copper influences transgenerational gene expression responses in Daphnia magna	8
Time-course full profiling of circulating miRNAs in neurologically deceased organ donors: a proof of concept study to understand the onset of the cytokine storm	8
Stress-induced epigenetic effects driven by maternal lactation in dairy cattle: a comethylation network approach	8
Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types	8
Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure	8
Parental arsenic exposure and tissue-specific DNA methylation in Bangladeshi infants with spina bifida	8
Comprehensive analysis of transcriptome‐wide M 6 A methylation for hepatic ischaemia reperfusion injury in mice	8
DNA methylation biomarkers to identify epigenetically abnormal spermatozoa in male partners from couples experiencing recurrent pregnancy loss	8
Memory B-cell like chronic lymphocytic leukaemia is associated with specific methylation profile of WNT5A promoter and undetectable expression of WNT5A gene	8
Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans	8
Epigenome-wide meta-analysis of prenatal vitamin D insufficiency and cord blood DNA methylation	8
Glucocorticoid receptor epigenetic activity in the heart	8
m6A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	8
Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer	8
Sex-based differences in placental DNA methylation profiles related to gestational age: an NIH ECHO meta-analysis	8
Anthropometric, biochemical, and haematological indicators associated with hyperhomocysteinemia and their relation to global DNA methylation in a young adult population	8
Circ_0003747 promotes thyroid cancer progression by sponging miR-338-3p to upregulate PLCD3 expression	8
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	8
Precise epigenomic editing with a SunTag-based modular epigenetic toolkit	8
Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows	8
Plasma methylated GNB4 and Riplet as a novel dual-marker panel for the detection of hepatocellular carcinoma	8
Epigenetic targeting of transposon relics: beating the dead horses of the genome?	8
Genome-wide methylation analysis in patients with proximal hypospadias – a pilot study and review of the literature	8
Fumonisin B 1 induces global DNA hypermethylation in human glioblastoma U87MG cells	7
In silico identification and in vitro expression analysis of breast cancer-related m6A-SNPs	7
Maternal adverse childhood experiences (ACEs) and offspring imprinted gene DMR methylation at birth	7
Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes	7
Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors	7
Combined exercise training decreases blood pressure in OLDER women with NOS3 polymorphism providing changes in differentially methylated regions (DMRs)	7
Spontaneous and ART-induced large offspring syndrome: similarities and differences in DNA methylome	7
Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction	7
Dose rate dependent reduction in chromatin accessibility at transcriptional start sites long time after exposure to gamma radiation	7
Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome	7
MK-801-exposure induces increased translation efficiency and mRNA hyperacetylation of Grin2a in the mouse prefrontal cortex	7
Implementation of the Methyl-Seq platform to identify tissue- and sex-specific DNA methylation differences in the rat epigenome	7
Chimpanzee Extraversion scores vary with epigenetic modification of dopamine receptor gene D2 (DRD2) and early rearing conditions	7
Imprinted gene alterations in the kidneys of growth restricted offspring may be mediated by a long non-coding RNA	7
DNA hypermethylation of CADM1, PAX5, WT1, RARβ, and PAX6 genes in oropharyngeal cancer associated with human papillomavirus	7
Epigenome-wide association study of global cortical volumes in generation Scotland: Scottish family health study	7
Identification of differentially methylated genes for severe acne by genome-wide DNA methylation and gene expression analysis	7
Animal and plant protein intake during infancy and childhood DNA methylation: a meta-analysis in the NutriPROGRAM consortium	6
Epigenome-wide association study of long-term psychosocial stress in older adults	6
Aberrant regulation of CXCR4 in cancer via deviant microRNA-targeted interactions	6
Homocysteine affects macrophage polarization by altering m6A methylation of scavenger receptors CD209 and CD163L1	6
Resistance and aerobic training increases genome-wide DNA methylation in women with polycystic ovary syndrome	6
Epigenetic ageing of the prefrontal cortex and cerebellum in humans and chimpanzees	6
Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells	6
In vivo DNA methylation editing in zebrafish	6
Letter to the editor: critical evaluation of the reliability of DNA methylation probes on the illumina MethylationEPIC v1.0 BeadChip microarrays	6
Vitamin C enhances co-localization of novel TET1 nuclear bodies with both Cajal and PML bodies in colorectal cancer cells	6
Pruning and thresholding approach for methylation risk scores in multi-ancestry populations	6
Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women	6
A qualitative prognostic biomarker for melanoma based on the relative methylation orderings of CpG loci	6
A promising application of kidney-specific cell-free DNA methylation markers in real-time monitoring sepsis-induced acute kidney injury	6
Evaluating the utility of ZNF331 promoter methylation as a prognostic and predictive marker in stage III colon cancer: results from CALGB 89803 (Alliance)	6
Correction	6

Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet	6
Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance)	6
IL21R hypomethylation as a biomarker for distinguishing benign and malignant breast tumours	6
Chromatin accessibility profiling of Treg cells in acute urticaria	6
YY1/circCTNNB1/miR-186-5p/YY1 positive loop aggravates lung cancer progression through the Wnt pathway	6
m 6 A RNA methylation regulators predict prognosis and indicate characteristics of tumour microenvironment infiltration in acute myeloid leukaemia	6
Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis	6
Sex-specific DNA methylation in saliva from the multi-ethnic Future of Families and Child Wellbeing Study	5
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations	5
CD4+T-cell DNA methylation changes during pregnancy significantly correlate with disease-associated methylation changes in autoimmune diseases	5
Phenotypic and transcriptomic impact of expressing mammalian TET2 in theDrosophila melanogastermodel	5
Circ-0006332 stimulates cardiomyocyte pyroptosis via the miR-143/TLR2 axis to promote doxorubicin-induced cardiac damage	5
Exploration of genome-wide DNA methylation profiles in night shift workers	5
Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus inPKP3in lung epithelial cells	5
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part I – the impact of inflammation	5
Astrocyte-derived exosomes regulate sperm miR-34c levels to mediate the transgenerational effects of paternal chronic social instability stress	5
Associations of green and blue space exposure in pregnancy with epigenetic gestational age acceleration	5
Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus	5
DNA methylation and gene expression changes in mouse mammary tissue during successive lactations: part II – the impact of lactation rank	5
Transmission of reduced levels of miR-34/449 from sperm to preimplantation embryos is a key step in the transgenerational epigenetic inheritance of the effects of paternal chronic social instability s	5
Early-pregnancy maternal body mass index is associated with common DNA methylation markers in cord blood and placenta: a paired-tissue epigenome-wide association study	5
Comparison between indicine and taurine cattle DNA methylation reveals epigenetic variation associated to differences in morphological adaptive traits	5
Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa	5
Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain	5
DNA hypomethylation mediates immune response in pan-cancer	5
Non-coding 886 ( nc886 / vtRNA2-1 ), the epigenetic odd duck – implications for future studies	5
Prenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood	5
Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues	5
Epigenetic editing of BRCA1 promoter increases cisplatin and olaparib sensitivity of ovarian cancer cells	5
LncRNA SCARNA8 promotes atherosclerotic plaque instability by inhibiting macrophage efferocytosis	5
LncRNA NEAT1 aggravates human microvascular endothelial cell injury by inhibiting the Apelin/Nrf2/HO-1 signalling pathway in type 2 diabetes mellitus with obstructive sleep apnoea	4
Dominant effects of the histone mutant H3-L61R on Spt16-gene interactions in budding yeast	4
Maternal plasma fatty acid patterns in mid-pregnancy and offspring epigenetic gestational age at birth	4
Oncogenic DNA methyltransferase 1 activates the PI3K/AKT/mTOR signalling by blocking the binding of HSPB8 and BAG3 in melanoma	4
Genome-wide methylation profile of mitochondrial DNA across bovine preimplantation development	4
DNA methylation heterogeneity attributable to a complex tumor immune microenvironment prompts prognostic risk in glioma	4
SOX6 AU controls myogenesis by cis-modulation of SOX6 in cattle	4
MIMOSA: a resource consisting of improved methylome prediction models increases power to identify DNA methylation-phenotype associations	4
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells	4
Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development	4
IL-18 serves as a main effector of CAF-derived METTL3 against immunosuppression of NSCLC via driving NF-κB pathway	4
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome	4
The effect of experimental lead pollution on DNA methylation in a wild bird population	4
Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study	4
A polyepigenetic glucocorticoid exposure score and HPA axis-related DNA methylation are associated with gestational epigenetic aging	4
Methylation profiles of global LINE-1 DNA and the GSTP1 promoter region in children exposed to lead (Pb)	4
A key regulatory loop AK4P1/miR-375/SP1 in pancreatic adenocarcinoma	4
Clinical significance of peripheral blood DDR1 and CtBP gene methylation detection in patients with acute pancreatitis	4
Epigenome-wide association study of systemic effects of obesity susceptibility in human twins	4
Perinatal stress and methylation of the NR3C1 gene in newborns: systematic review	4
FTO promotes proliferation and migration of bladder cancer via enhancing stability of STAT3 mRNA in an m6A-dependent manner	4