OOIR: Observatory of International Research

Papers

(The TQCC of Epigenetics is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Epigenetic mechanisms regulating COVID-19 infection	97
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons	51
Comprehensive analysis of the transcriptome-wide m6A methylome in colorectal cancer by MeRIP sequencing	50
The Socioeconomic Gradient in Epigenetic Ageing Clocks: Evidence from the Multi-Ethnic Study of Atherosclerosis and the Health and Retirement Study	39
Saliva cell type DNA methylation reference panel for epidemiological studies in children	37
Estrogen-induced epigenetic silencing of FTH1 and TFRC genes reduces liver cancer cell growth and survival	33
Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes	33
The landscape of accessible chromatin in bovine oocytes and early embryos	33
Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease	29
Fusaric acid decreases p53 expression by altering promoter methylation and m6A RNA methylation in human hepatocellular carcinoma (HepG2) cells	28
SET1/MLL family of proteins: functions beyond histone methylation	28
Genomic map of candidate human imprint control regions: the imprintome	27
Mitochondrial DNA methylation in placental tissue: a proof of concept study by means of prenatal environmental stressors	26
Music-listening regulates human microRNA expression	25
Prenatal gestational diabetes mellitus exposure and accelerated offspring DNA methylation age in early childhood	25
DNA methylation profile of genes involved in inflammation and autoimmunity correlates with vascular function in morbidly obese adults	24
Minimally invasive classification of paediatric solid tumours using reduced representation bisulphite sequencing of cell-free DNA: a proof-of-principle study	24
Recent insights intoHistone Acetyltransferase-1: biological function and involvement in pathogenesis	23
Micronutrient supplementation affects transcriptional and epigenetic regulation of lipid metabolism in a dose-dependent manner	22
Associations between maternal lifetime stressors and negative events in pregnancy and breast milk-derived extracellular vesicle microRNAs in the programming of intergenerational stress mechanisms (PRI	20
Sources of variation of DNA methylation in rainbow trout: combined effects of temperature and genetic background	19
Comparison of EM-seq and PBAT methylome library methods for low-input DNA	19
Reliability of DNA methylation measures using Illumina methylation BeadChip	19
Sex-specific associations with DNA methylation in lung tissue demonstrate smoking interactions	19
The DNA methylation landscape of human cancer organoids available at the American type culture collection	19

The m6A epitranscriptome opens a new charter in immune system logic	19
Test-statistic inflation in methylome-wide association studies	19
Epigenetic alterations as therapeutic targets in Testicular Germ Cell Tumours : current and future application of ‘epidrugs’	19
Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels	18
Genome-wide study of the effect of blood collection tubes on the cell-free DNA methylome	18
Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours	18
Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein	17
Hypermethylation of the oxytocin receptor gene (OXTR) in obsessive-compulsive disorder: further evidence for a biomarker of disease and treatment response	17
HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation	17
Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome	17
Neuronal Lhx1 expression is regulated by DNMT1-dependent modulation of histone marks	16
Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use	16
Adolescent sleep timing and dietary patterns in relation to DNA methylation of core circadian genes: a pilot study of Mexican youth	16
DNA methylation in the promoters of PD-L1, MMP9, ARG1, galectin-9, TIM-3, VISTA and TGF-β genes in HLA-DR^– myeloid cells, compared with HLA-DR⁺ antigen-presenting cells	16
microRNA27a-3p mediates reduction of the Wnt antagonist sFRP-1 in systemic sclerosis	15
Characterizing the dynamic and functional DNA methylation landscape in the developing human cortex	15
Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation – can blood be used as a surrogate for bone?	15
Tissue and sex-specific programming of DNA methylation by perinatal lead exposure: implications for environmental epigenetics studies	15
Birth weight associations with DNA methylation differences in an adult population	15
m⁶A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2	14
Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells	14
Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures	14
DNA methylation signatures of adolescent victimization: analysis of a longitudinal monozygotic twin sample	14
TET family regulates the embryonic pluripotency of porcine preimplantation embryos by maintaining the DNA methylation level of NANOG	14
The epigenetics of breast cancer – Opportunities for diagnostics, risk stratification and therapy	14
Global epigenetic alterations of mesenchymal stem cells in obesity: the role of vitamin C reprogramming	14
Methylomic Signatures of High Grade Serous Ovarian Cancer	13
DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis	13
Maternal blood metal concentrations and whole blood DNA methylation during pregnancy in the Early Autism Risk Longitudinal Investigation (EARLI)	13
Comprehensive analysis of transcriptome-wide m⁶A methylome in the anterior capsule of the lens of high myopia patients	13
Cell-free DNA methylome profiling by MBD-seq with ultra-low input	13
Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study	13
Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis	13
Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples	13
Effects of substrate modifications on the arginine dimethylation activities of PRMT1 and PRMT5	13
Suppressing circIDE/miR-19b-3p/RBMS1 axis exhibits promoting-tumour activity through upregulating GPX4 to diminish ferroptosis in hepatocellular carcinoma	13
DNA methylation differentiates smoking from vaping and non-combustible tobacco use	12
Genome-wide DNA methylation differences and polychlorinated biphenyl (PCB) exposure in a US population	12
DNA methylation and hydroxymethylation have distinct genome-wide profiles related to axonal regeneration	12
Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications	12
Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development	12
NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status	12
Genome-wide microRNA expression analysis in human placenta reveals sex-specific patterns: an ENVIRONAGE birth cohort study	12
Cell type-specific chromatin accessibility analysis in the mouse and human brain	12
DNA methylation ageing clocks and pancreatic cancer risk: pooled analysis of three prospective nested case-control studies	11
A comparison of epithelial cell content of oral samples estimated using cytology and DNA methylation	11
Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects	11
Early fish domestication affects methylation of key genes involved in the rapid onset of the farmed phenotype	11
A mathematical model exhibiting the effect of DNA methylation on the stability boundary in cell-fate networks	11
Placental microRNA expression associates with birthweight through control of adipokines: results from two independent cohorts	11

Association ofSOD3 promoter DNA methylation with its down-regulation in breast carcinomas	11
Molecular signatures identified by integrating gene expression and methylation in non-seminoma and seminoma of testicular germ cell tumours	11
Exposure to extracellular vesicles from Pseudomonas aeruginosa result in loss of DNA methylation at enhancer and DNase hypersensitive site regions in lung macrophages	11
Methylation of FKBP5 is associated with accelerated DNA methylation ageing and cardiometabolic risk: replication in young-adult and middle-aged Black Americans	11
Epigenome-wide scan identifies differentially methylated regions for lung cancer using pre-diagnostic peripheral blood	10
Dynamic changes in DNA methylation occur in TE regions and affect cell proliferation during leaf-to-callus transition in Arabidopsis	10
Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth	10
Identifying cortical specific long noncoding RNAs modified by m⁶A RNA methylation in mouse brains	10
A genome-wide study of DNA methylation in white blood cells and asthma in Latino children and youth	10
DNA methylation biomarker selected by an ensemble machine learning approach predicts mortality risk in an HIV-positive veteran population	10
Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome	10
Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort	10
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells	10
A novel CpG-methylation-based nomogram predicts survival in colorectal cancer	10
DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients	10
Age-related DNA methylation in paired normal and tumour breast tissue in Chinese breast cancer patients	10
m ⁶ A-modification regulated circ-CCT3 acts as the sponge of miR-378a-3p to promote hepatocellular carcinoma progression	10
Maternal atopy and offspring epigenome-wide methylation signature	10
“Epigenome-wide methylation profile of chronic kidney disease-derived arterial DNA uncovers novel pathways in disease-associated cardiovascular pathology.”	9
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer	9
Dynamic chromatin accessibility landscape changes following interleukin-1 stimulation	9
DNA methylome in visceral adipose tissue can discriminate patients with and without colorectal cancer	9
Ten-eleven translocation proteins and their role beyond DNA demethylation – what we can learn from the fly	9
Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors	9
Prenatal smoke exposure induces persistent Cyp2a5 methylation and increases nicotine metabolism in the liver of neonatal and adult male offspring	9
Epigenetic regulation of miR-518a-5p-CCR6 feedback loop promotes both proliferation and invasion in diffuse large B cell lymphoma	9
Germline DNMT3A mutation in familial acute myeloid leukaemia	9
The hypomethylation of imprinted genes in IVF/ICSI placenta samples is associated with concomitant changes in histone modifications	9
Perinatal stress and methylation of the NR3C1 gene in newborns: systematic review	9
Epigenetic Aging Mediates the Association between Pain Impact and Brain Aging in Middle to Older Age Individuals with Knee Pain	9
Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans	9
NSUN2-mediated RNA m⁵C modification modulates uveal melanoma cell proliferation and migration	8
Association between dietary patterns reflecting one-carbon metabolism nutrients intake before pregnancy and placental DNA methylation	8
The effect of experimental lead pollution on DNA methylation in a wild bird population	8
A methodological pipeline to generate an epigenetic marker of prenatal exposure to air pollution indicators	8
CYP2S1 might regulate proliferation and immune response of keratinocyte in psoriasis	8
Birth weight and maternal energy status during pregnancy as predictors of epigenetic age acceleration in young adults from metropolitan Cebu, Philippines	8
Deacetylation of H4 lysine16 affects acetylation of lysine residues in histone H3 and H4 and promotes transcription of constitutive genes	8
Long non-coding RNA Gm10561 promotes myogenesis by sponging miR-432	8
Functional study and epigenetic targets analyses of SIRT1 in intramuscular preadipocytes via ChIP-seq and mRNA-seq	8
Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution	8
Establishment of diagnostic criteria for upper urinary tract urothelial carcinoma based on genome-wide DNA methylation analysis	8
A Comparison of the Predictive Power of DNA Methylation with Carbohydrate Deficient Transferrin for Heavy Alcohol Consumption	8
Prenatal medication exposure and epigenetic outcomes: a systematic literature review and recommendations for prenatal pharmacoepigenetic studies	8
Maternal Mediterranean diet in pregnancy and newborn DNA methylation: a meta-analysis in the PACE Consortium	8
A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation	8
Identification and comparison of m6A modifications in glioblastoma non-coding RNAs with MeRIP-seq and Nanopore dRNA-seq	8
Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA	8
ABCA1, TCF7, NFATC1, PRKCZ, and PDGFA DNA methylation as potential epigenetic-sensitive targets in acute coronary syndrome via network analysis	8