OOIR: Observatory of International Research

Papers

(The median citation count of Current Neurovascular Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Antidepressant Effect of Sodium Butyrate is Accompanied by Brain Epigenetic Modulation in Rats Subjected to Early or Late Life Stress	36
Predicting Futile Recanalization in Acute Ischemic Stroke Patients Undergoing Endovascular Thrombectomy: The Role of White Blood Cell Count to Mean Platelet Volume Ratio	33
A Common Link in Neurovascular Regenerative Pathways: Protein Kinase B (Akt)	26
Acute Ischaemic Stroke Incidence after Coronavirus Vaccine in Indonesia: Case Series	20
Smurf2-Mediated Ubiquitination of FOXO4 Regulates Oxygen-glucose Deprivation/Reperfusion-induced Pyroptosis of Cortical Neurons	19
Pyroptosis, Apoptosis, and Autophagy: Critical Players of Inflammation and Cell Demise in the Nervous System	18
Biomarkers for Parkinson’s Disease and Neurodegenerative Disorders: A Role for Non-coding RNAs	18
Relationship of the Low-Density Lipoprotein Cholesterol/High-Density Lipoprotein Cholesterol Ratio with a Vulnerable Plaque in Patients with Severe Carotid Artery Stenosis: A Case-Control Study in the	16
miR-666-3p Mediates the Protective Effects of Mesenchymal Stem Cell-derived Exosomes Against Oxygen-glucose Deprivation and Reoxygenation-induced Cell Injury in Brain Microvascular Endothelial Cells v	16
Caffeic Acid Phenethyl Ester (CAPE) Attenuates Paclitaxel-induced Peripheral Neuropathy: A Mechanistic Study	16
Gait Parameters can Reflect Cognitive Performance in Older Adults with Cerebral Small Vessel Disease: A Cross-sectional Research	13
Poly (Adenosine Diphosphate Ribose) Polymerase-1 Single Nucleotide Polymorphism in the 3'-Untranslated Region for Ischemic Stroke Risk Reduction	13
Electroacupuncture Inhibits Ferroptosis Induced by Cerebral Ischemiareperfusion	13
Sleep Disorders, Neurodegeneration, Glymphatic Pathways, and Circadian Rhythm Disruption	13
Dual Specificity Phosphatase 3 (DUSP3) Knockdown Alleviates Acute Myocardial Infarction Damage via Inhibiting Apoptosis and Inflammation	13
Whole Transcriptome Sequencing of Peripheral Blood Identifies the Alzheimer's Disease-Related circRNA-miRNA-lncRNA Pathway	12
Tandem Mass Tag (TMT) Quantitative Proteomic Analysis of Serum Exosomes in Cerebral Small-vessel Disease (CSVD) Patients With Depressive Symptoms	12
Electroacupuncture Inhibits Neural Ferroptosis in Rat Model of Traumatic Brain Injury via Activating System Xc⁻/GSH/GPX4 Axis	11
Electro-acupuncture Promotes Angiogenesis via Exosomal miR-210 in the Hypoxia-induced HUVECs Mediated HIF-1α/VEGF/Notch 1 Signal Pathway	10
A Clinical Model predicting the 90-Day Prognosis after Mechanical Thrombectomy in Patients with Acute Ischemic Stroke: A Retrospective Study	10
The Value of Arterial Spin Labeling Imaging in the Classification and Prognostic Evaluation of Neonatal Hypoxic-ischemic Encephalopathy	9
Nomogram Models for Predicting Poor Prognosis in Lobar Intracerebral Hemorrhage: A Multicenter Study	9
Malignant Middle Cerebral Artery Infarction during Early versus Late Endovascular Treatment in Acute Ischemic Stroke	9
The Metabolic Basis for Nervous System Dysfunction in Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease	9
Effect of Early Balloon Inflation of Balloon Guide Catheter in Mechanical Thrombectomy for Large Vessel Occlusion	9

The Interplay Among Epilepsy, Parkinson’s Disease and Inflammation: Revisiting the Link through Ca2+/cAMP Signalling	9
Association of Alkaline Phosphatase Level with Futile Recanalization in Acute Ischemic Stroke Patients Treated with Endovascular Thrombectomy	8
Evaluation of Quantitative and Selective Sensory Fiber Dysfunction in Patients with Cirrhosis	8
Albumin-Globulin Ratio and Common Carotid Artery Intima-Media Thickness in Patients with Ischemic Stroke	8
Observation of the Therapeutic Effect of Correcting Foot Varus on Improving Knee Hyperextension and Gait in Patients After Stroke	8
Estrogen Receptor 1 Gene rs22346939 and rs9340799 Variants are Associated with Major Depressive Disorder and its Clinical Features	8
DDX3X Deficiency Attenuates Pyroptosis Induced by Oxygen-glucose Deprivation/Reoxygenation in N2a Cells	8
Assessment of the Roles of Magnesium and Zinc in Clinical Disorders	7
CD31+ Circulating Angiogenic Cell Number and Subtypes are Reduced in Individuals with Chronic Stroke	7
Risk Factors for Cerebral Hyperperfusion Syndrome After Combined Revascularization in Adult Patients with Moyamoya Disease	7
Association between Interleukin-6 and Multiple Acute Infarctions in Symptomatic Intracranial Atherosclerotic Disease	7
Wheel Running Adversely Affects Disease Onset and Neuromuscular Interplay in Amyotrophic Lateral Sclerosis Slow Progression Mouse Model	7
DL-3-n-butylphthalide Attenuates Cerebral Ischemia-Reperfusion Injury by Inhibiting Mitochondrial Omi/HtrA2-Mediated Apoptosis	7
Timing of Tracheostomy in Patients with Intracerebral Haemorrhage: A Propensity-Matched Analysis	7
Heme Oxygenase-1 may Mediate Early Inflammatory Response of Intracerebral Hemorrhage through Toll-like Receptor 4 Signaling Pathway	7
Curcumin Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting NLRP1-dependent Neuronal Pyroptosis	7
Nomogram to Predict Symptomatic Intracranial Hemorrhage after Intravenous Thrombolysis in Acute Ischemic Stroke in Asian Population	7
Association of Serum Interleukin-34 and Insulin Resistance with Cognitive Impairment in Patients with Cerebral Small Vessel Disease	7
The Role of Serum Secretoneurin Levels in Patients with Traumatic Brain Injury	6
Risk Factors for Silent Brain Infarction in Nonvalvular Atrial Fibrillation Patients with Low CHA₂DS₂-VASc Score	6
P75NTR Exacerbates SCI-induced Mitochondrial Damage and Neuronal Apoptosis Depending on NTRK3	6
Electroacupuncture Alleviates Cerebral Ischemia-reperfusion Injury by Regulating the S1PR2/TLR4/NLRP3 Signaling Pathway via m6A Methylation of lncRNA H19	6
TRUST Technique for Neurointervention: A Promising Alternative for Complex Cases	6
Clinical Efficacy of Functional Electrical Stimulation-assisted Rehabilitation Cycling on the Function of Lower Limbs in Patients with Stroke	6
The Safety and Efficacy of Leo Stents with Coiling or Alone for Anterior Cerebral Artery Aneurysms	5
Neutrophil-to-albumin Ratio as a Prognostic Factor in Patients with Acute Ischemic Stroke	5
Protective Effect of GSK-3β/Nrf2 Mediated by Dimethyl Fumarate in Middle Cerebral Artery Embolization Reperfusion Rat Model	5
Primary Changes in Corneal Nerve Fiber Structure in Patients with Primary Glaucoma and Related Influencing Factors	5
Efficacy and Safety of Alteplase on Treatment of Acute Single Small Subcortical Infarction	5
Higher NT-proBNP Levels are Related to Poor Functional Outcome and Pneumonia in Acute Intracerebral Hemorrhage Patients	5
Myasthenia Gravis and Ischemic Stroke: A Bidirectional Mendelian Randomization Study	5
Intravenous Thrombolysis is Effective in Mild Stroke Patients with an Admission NIHSS Score of 3 to 5	5
Electroacupuncture Serum Protects against Blood-brain Barrier Damage after Ischemic Stroke by Regulating Pericytes in vitro	5
MicroRNA-17-5p Promotes Vascular Calcification by Targeting ANKH	5
Development of a Nomogram for Predicting Asymptomatic Coronary Artery Disease in Patients with Ischemic Stroke	5
Analysis of the Relationship between Recent Small Subcortical Infarcts and Autonomic Nervous Dysfunction	5
Nanotechnology in Drug Delivery: An Overview of Developing the Blood Brain Barrier	5
Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders	5
Regulatory mechanism of the SNHG3/miR-302a-3p/E2F1 feedback loop in nerve repair post cerebral ischemic stroke	5
Novel Insights for Multiple Sclerosis and Demyelinating Disorders with Apoptosis, Autophagy, FoxO, and mTOR	5
Genome-wide Association Studies of REST Gene Associated Neurological Diseases/traits with Related Single Nucleotide Polymorphisms	5
Prediction of Symptoms on Admission with Early Neurological Deterioration in Single Small Subcortical Infarct	5
Comparison of 4 mm-sized and 3 mm-sized Stent Retrievers in Mechanical Thrombectomy for M2 Occlusion	4
Association between HbA1C (Glycated Hemoglobin) and Clinical Outcomes in Patients with Subarachnoid Hemorrhage After Neuro-intervention	4
Downregulation of CHCHD2 may Contribute to Parkinson’s Disease by Reducing Expression of NFE2L2 and RQCD1	4
The Effect of Acupuncture on Enteral Nutrition and Gastrointestinal Dynamics in Patients Who Have Suffered a Severe Stroke	4
Crocetin Enhances Temozolomide Efficacy in Glioblastoma Therapy Through Multiple Pathway Suppression	4
Enlarged Perivascular Space in the Basal Ganglia is Associated with Cerebral Venous Reflux in Patients with Recent Small Subcortical Infarction	4
Impact of Stroke Severity on the Smoking Paradox in Patients Treated with Intravenous Thrombolysis	4
Inhibition of Circ0001679 Alleviates Ischemia/Reperfusion-induced Brain Injury via miR-216/TLR4 Regulatory Axis	4

High Prevalence of Cerebral Microbleeds in Young Ischemic Stroke Patients	4
Smoking, Coffee Consumption, Alcohol Intake, and Obstructive Sleep Apnea: A Mendelian Randomization Study	4
Association between Cerebral Blood Volume Index and Excellent Reperfusion in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy	4
Feasibility and Efficacy of Low-profile Visual Intraluminal Support Device: A Single Center Five-year Experience	4
The Positional Relationship between Lacunae and White Matter Hyperintensity in Patients with Cerebral Small Vessel Disease	4
Value of IMA, IMAR, the IMA Index, and Other Hematological Features in Predicting AIS Caused by MCA Stenosis/Occlusion	4
CT Perfusion Metrics as Indicators of Intracranial Atherosclerotic Stenosis in Acute Ischemic Stroke: A Clinical Analysis	4
Peripheral Neuropathy: An Early Indication of Systemic Disease that Involves the Mechanistic Target of Rapamycin (mTOR)	4
Circadian Rhythm, Clock Genes, and Stroke	4
The Effect of Remote Ischemic Postconditioning on Quality of Life and Clinical Events after an Ischemic Stroke	4
Prognostic Value of Serum Bilirubin in Aneurysmal Subarachnoid Hemorrhage Patients	4
The Impact of Sirtuins, Erythropoietin, and Hypoxia-inducible Factor-1 on Neurovascular Disease	4
The Association between Serum Total Bilirubin and Severe Headaches or Migraine in American Adults	4
Irregular Baseline Brain Activity in Coronary Artery Disease Patients with Cognitive Impairment: A Resting-state Functional Magnetic Resonance Imaging Study	4
Combination of Peroxisome Proliferator-activated Receptor Gamma (PPARγ) Agonist and PPAR Gamma Co-Activator 1α (PGC-1α) Activator Ameliorates Cognitive Deficits, Oxidative Stress, and Inflammation in	4
Effect on Successful Recanalization of Thrombus Length in Susceptibility- weighted Imaging in Mechanical Thrombectomy with Stentretrieval	3
A Nomogram Prediction Model Based on Tissue Window for the Prognosis of Patients with Acute Ischemic Stroke Undergoing Thrombectomy	3
The Association of the Spatial Location of Contrast Extravasation with Symptomatic Intracranial Hemorrhage after Endovascular Therapy in Acute Ischemic Stroke Patients	3
Ang-1 Inhibited Endoplasmic Reticulum Stress and Apoptosis of VECs in Rats with aSAH-induced CVS Through the Regulated PI3K/Akt Pathway	3
Neutrophil-to-lymphocyte Ratio Predicts the Outcome of Cerebral Venous Thrombosis	3
Plumbagin's Healing Effect on Motor Impairment in Rotenone-toxified Rodents	3
Vulnerable Carotid Plaque is Associated with an Increased Risk of Intracerebral Hemorrhage in Individuals at High Risk of Stroke: A Chinese Population-based Cohort Study	3
Safety of Mechanical Thrombectomy for Acute Ischemic Stroke in Patients with Thrombocytopenia	3
Alcohol Use Disorder and Dementia: Critical Mechanisms for Cognitive Loss	3
Electroacupuncture Pretreatment Alleviates Cerebral Ischemia-reperfusion Injury by Down-regulating Mir-155-5p	3
Plasma Retinol Binding Protein 4 as a Biomarker for Detecting Progressive Stroke and Prediction of Early Prognosis in Patients with Acute Ischemic Stroke	3
Microglia: Formidable Players in Alzheimer’s Disease and Other Neurodegenerative Disorders	3
Pan-Immune-Inflammatory Value Predicts the 3 Months Outcome in Acute Ischemic Stroke Patients after Intravenous Thrombolysis	3
Sevoflurane Post-treatment Mitigates Oxygen-glucose Deprivationinduced Pyroptosis of Hippocampal Neurons by Regulating the Mafb/DUSP14 Axis	3
Insights of Valacyclovir in Treatment of Alzheimer’s Disease: Computational Docking Studies and Scopolamine Rat Model	3
Predictors of Emboli in Mechanical Thrombectomy for Anterior Circulation Stroke	3
The Effect of Systemic Inflammatory Response on Mechanical Thrombectomy is Partly Mediated by Pre-thrombectomy Cerebral Edema in Acute Stroke Patients	3
APOE4: A Culprit for the Vulnerability of COVID-19 in Alzheimer's Patients	3
The Correlation Between Modified Total Cerebral Small Vessel Disease Score and Gait and Balance Disorder in Middle-aged to Older Adults	3
Major Targets Involved in Clinical Management of Migraine	3
Prevalence and Prognostic Factors of Cortical Laminar Necrosis in Acute Ischemic Stroke	3
A Simple Score for Predicting Paroxysmal Atrial Fibrillation in Patients with Embolic Stroke of Undetermined Source in a Tunisian Cohort Study	3
The Role of Thrombo-inflammatory Biomarkers in the Prognosis of Cerebral Venous Sinus Thrombosis	3
MiR-582-5p Attenuates Neonatal Hypoxic-ischemic Encephalopathy by Targeting High Mobility Group box 1 (HMGB1) through Inhibiting Neuroinflammation and Oxidative Stress	3
Does Weekends Effect Exist in Asia? Analysis of Endovascular Thrombectomy for Acute Ischemic Stroke in A Medical Center	2
Keap1 as Target of Genistein on Nrf2 Signaling Pathway Antagonizing Aβ induced Oxidative Damage of Cerebrovascular Endothelial Cells	2
Relationship between Preoperative and Postoperative Peripheral Oxygen Saturation and Malignant Brain Edema in Stroke Patients Undergoing Mechanical Thrombectomy	2
The Impact of the Initial Admission Department on the Management and Prognosis of Retinal Artery Occlusion	2
Creation of Retinal Vein Occlusion Model in Cynomolgus Monkeys and Determination of its Pathological Features	2
Decoding the Transcriptional Response to Ischemic Stroke in Obese and Non-obese Mice Brain	2
Apolipoprotein-ε4 allele (APOE-ε4) as a Mediator of Cognitive Loss and Dementia in Long COVID-19	2
Ferroptosis, Iron Metabolism, and Forkhead Transcription Factors (FoxOs)	2
Association of Posture Instability with Dopamine Drop of Nigrostriatal System and Hypometabolism of Cerebral Cortex in Parkinson’s Disease	2
Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury	2
Does Hyperdense Middle Cerebral Artery Sign Predict the Prognosis of Patients Undergoing Emergency Endovascular Treatment?	2
P2RY12 Increased Neuroinflammation to Accelerate Depression-like Behaviors by the NLPR3 Inflammasome	2
Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids’ Producer as Protective Factor of Cerebrovascular Disease	2
Correlation between Carotid Blood Flow Velocity and Total Magnetic Resonance Imaging Burden of Cerebral Small Vessel Disease in Patients with Recent Small Subcortical Infarcts	2
Anti-Inflammatory Effect of Ginsenoside Rg1 on LPS-Induced Septic Encephalopathy and Associated Mechanism	2
Association between Plasma Brain-derived Neurotrophic Factor Level and Alzheimer’s Disease: A Mendelian Randomization Study	2
The Study of Risk Factors and The Predict Model of Cerebral Microbleeds	2
Impact of Headache Frequency and Sleep on Migraine Patients During the COVID-19 Pandemic	2
Elongated Internal Carotid Arteries in Patients with Severe Carotid Artery Stenosis	2
Plasma Osteoprotegerin and Cognitive Impairment after Ischemic Stroke	2
Diindolylmethane Ameliorates Ischemic Stroke-Induced Brain Injury by Peripheral and Central Mechanisms	2
The Effect of Dexamethasone on Lipopolysaccharide-induced Inflammation of Endothelial Cells of the Blood-brain Barrier/Brain Capillaries	2
Cognitive Impairment and Mossy Fiber Sprouting in a Rat Model of Drug-resistant Epilepsy Induced by Lithium-pilocarpine	2
The Mechanism of Astragaloside IV in NOD-like Receptor Family Pyrin Domain Containing 3 Inflammasome-mediated Pyroptosis after Intracerebral Hemorrhage	2
Nonfocal Symptoms in Patients with Transient Ischemic Attack and Association with Stroke Risk	2
Association Between Cardiometabolic Index and Stroke: A Population- based Cross-sectional Study	2
Association of Nocturnal Heart Rate with White Matter Hyperintensity Burden in Cerebral Small Vessel Disease Patients	2
Activation of Src Kinase Mediates the Disruption of Adherens Junction in the Blood-labyrinth Barrier after Acoustic Trauma	2
Modified Risk of Paradoxical Embolism More Effectively Evaluates the Risk of Stroke Associated with Patent Foramen Ovale	2
Regulatory Effect of Electroacupuncture on Hypothalamic Serotonin and its Receptor in Rats with Cerebral Ischemia	2
Association of Blood Lipid Profile Components with White Matter Hyperintensity Burden in Cerebral Small Vessel Disease	2
Analysis of Prognostic Risk Factors for Ischemic Stroke in China: A Multicentre Retrospective Clinical Study; A National Survey in China	2