OOIR: Observatory of International Research

Papers

(The H4-Index of International Immunopharmacology is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
In-vitro and in-silico evaluation of rue herb for SARS-CoV-2 treatment	635
Unveiling the impact of Cancer-IgG on glioma: Insights into biological behavior and macrophage polarization dynamics	243
Fut2 deficiency aggravates chronic colitis through 2-oxindole-AHR mediated cGAS-STING pathway	160
C1q/TNF-related protein-9 promotes diabetic wound healing by enhancing dendritic cell efferocytosis via the ATF3/SLC7A11 signaling axis	119
CD83 mediates the inhibitory effect of the S1PR1 agonist CYM5442 on LPS-induced M1 polarization of macrophages through the ERK-STAT-1 signaling pathway	112
Role of S100A1, S100A4, S100A8/A9 and S100B in myocardial infarction and heart failure	110
VX-509 (Decernotinib)-modified tolerogenic dendritic cells alleviate experimental autoimmune neuritis by promoting Th17/Treg rebalance	105
Deletion of BMP4 impairs trophoblast function and decidual macrophage polarization via autophagy leading to recurrent spontaneous abortion	103
Editorial Board	103
Skin inflammation and lipid disorder induced by topical application of Mal f 1	97
Corrigendum to “Combined diosmin and bisoprolol attenuate cobalt chloride-induced cardiotoxicity and endothelial dysfunction through modulating miR-143-3P/MAPK/MCP-1, ERK5/CXCR4, Orai-1/STIM-1 signali	87
Dexmedetomidine therapy promotes cardiac dysfunction and increases mortality in sepsis: A translational study	86
Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression	86
A novel combination therapy using Dapagliflozin and Cycas media extract in experimentally induced diabetic wounds by targeting novel pathways in wound healing	85
Quantitative analysis of immune cells within the tumor microenvironment of glioblastoma and their relevance for prognosis	84
Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-19	84
Ferroptosis in organ fibrosis: Mechanisms and therapeutic approaches	81
High-titer rheumatologic markers in serum of veterans with severe pulmonary complications 25–30 years after sulfur mustard exposure	81
Antiproliferative and apoptotic effects of (1R,12R)-dolabella-4(16),7,10-triene-3,13-dione (CI-A) in oral cancer cells are mediated by oxidative stress and ERK activation	80
“The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease”	80
Role of macrophages in cardiac arrhythmias: Pathogenesis and therapeutic perspectives	79
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice	77
Efficacy and safety of anti-CD19 CAR-T in a mouse model of IgG4-related disease	70
Antitumor effect of invasive Lactobacillus plantarum delivering associated antigen gene sHSP between Trichinella spiralis and Lewis lung cancer cells	69
Unravelling the role of Interleukin-12 in Neuroinflammatory mechanisms: Pathogenic pathways linking Neuroinflammation to neuropsychiatric disorders	69

Molecular pathways and biological roles of melatonin and vitamin D; effects on immune system and oxidative stress	67
Dual-sensitive gelatin-coated chitosan microparticles for targeted semaglutide pulmonary delivery: a novel approach to enhancing anti-inflammatory and anti-fibrotic effects	66
27-hydroxycholesterol roles in respiratory disease pathogenesis	64
Cyclic helix B peptide alleviates liver fibrosis via attenuating ROS-mediated pyroptosis	64
LXA4 attenuates perioperative neurocognitive disorders by suppressing neuroinflammation and oxidative stress	63
The role of cGAS-STING signaling pathway in colorectal cancer immunotherapy: Mechanism and progress	63
An “On Demand” canakinumab regimen for treating children with Colchicine-Resistant familial Mediterranean fever – A multicentre study	62
Procyanidin B2 targeted CCR7 expression to inhibit the senescence-associated secretory phenotype through the NF-κB pathway to promote osteogenic differentiation of periodontal ligament stem cells in p	62
The role of lncRNA and miRNA on the effects of occurrence and development of osteosarcoma	62
IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry	61
VX765 alleviates dextran sulfate sodium-induced colitis in mice by suppressing caspase-1-mediated pyroptosis	61
Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity: Therapeutic potential against SARS-CoV-2 (COVID-19)	61
VSIG4 induces the immunosuppressive microenvironment by promoting the infiltration of M2 macrophage and Tregs in clear cell renal cell carcinoma	61
Macrophage-derived GSDMD promotes abdominal aortic aneurysm and aortic smooth muscle cells pyroptosis	61
Efficacy and safety of tofacitinib in the treatment of adults with lichen planopilaris: A randomized placebo-controlled trial	60
Review of the effects and Mechanisms of microglial autophagy in ischemic stroke	60
Association between γδ T cells and clinicopathological features of breast cancer	59
Intervention of neuroinflammation in the traumatic brain injury trajectory: In vivo and clinical approaches	58
GDF11 alleviates spinal cord injury in rats by modulating microglia polarization through Smad2/3 and MAPK/NFκB signaling pathways	58
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron	58
Comprehensive transcriptomic analyses identify the immunosuppressive effects of LLDT-8 in ART-treated SIV-infected rhesus macaques	58
Clinical evidence for the prognostic impact of metformin in cancer patients treated with immune checkpoint inhibitors	57
Sunitinib attenuates reactive MDSCs enhancing anti-tumor immunity in HNSCC	55
ILC2s control obesity by regulating energy homeostasis and browning of white fat	55
The impact of long-term oral exposure to low doses of acrylamide on the hematological indicators, immune functions, and splenic tissue architecture in rats	54
An overview of immune checkpoint therapy in autoimmune diseases	53
Disulfiram attenuates MCMV-Induced pneumonia by inhibition of NF-κB/NLRP3 signaling pathway in immunocompromised mice	53
Codelivery of triptolide and IFN-γ to boost antitumor immunity for triple-negative breast cancer	53
Comprehensive analysis of a pyroptosis-related gene signature of clinical and biological value in acute myeloid leukaemia	53
Impact of inflammation and anti-inflammatory modalities on diabetic cardiomyopathy healing: From fundamental research to therapy	53
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization	53