OOIR: Observatory of International Research

Papers

(The H4-Index of International Immunopharmacology is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Inhibition of non-receptor tyrosine kinase LCK partially mitigates mixed granulocytic airway inflammation in a murine model of asthma	496
Forsythiaside A alleviates acute lung injury via the RNF99/TRAF6/NF-κB signaling pathway	276
Corrigendum to “Maackiain protects against sepsis via activating AMPK/Nrf2/HO-1 pathway” [Int. Immunopharmacol. 108 (2022) 108710]	268
Huanglian Jiedu Decoction enhances the stability of atherosclerotic plaques through SLC2A1-mediated efferocytosis	162
The activation of TLR4-MyD88 signaling promotes hepatic dysfunction and fibrotic changes in SD rats resulting from prolonged exposure to sodium arsenite	139
Erratum to “Auraptene-ameliorating depressive-like behaviors induced by lipopolysaccharide combined with chronic unpredictable mild stress in mice mitigate hippocampal neuroinflammation mediated by mi	136
Retraction notice to “Bone marrow-derived mesenchymal stem cells-secreted exosomal microRNA-192-5p delays inflammatory response in rheumatoid arthritis” [Int. Immunopharmacol. 78 (2020) 105985]	135
Retraction notice to “MLL1 promotes migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis by activating the TRIF/NF-κB signaling pathway via H3K4me3 enrichment in the TLR4 pro	123
Retraction notice to “MicroRNA-208-5p regulates myocardial injury of sepsis mice via targeting SOCS2-mediated NF-κB/HIF-1a pathway” [Int. Immunopharmacol. 81 (2020) 106204]	118
Expression of concern: “Long non-coding RNA THRIL promotes LPS-induced inflammatory injury by down-regulating microRNA-125b in ATDC5 cells” [International Immunopharmacology 66 (2019) 354–361]	105
Expression of concern: “Long non-coding RNA highly up-regulated in liver cancer protects tumor necrosis factor-alpha-induced inflammatory injury by down-regulation of microRNA-101 in ATDC5 cells” [Int	87
RETRACTED: TRIM21 deficiency confers protection from OGD/R-induced oxidative and inflammatory damage in cultured hippocampal neurons through regulation of the Keap1/Nrf2 pathway	86
Retraction notice to “BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice” [Int. Immunopharmacol. 93 (2021) 107389]	82
Association between γδ T cells and clinicopathological features of breast cancer	81
A druggable targets discovery strategy for diseases (DTDS): Taking Rheumatoid arthritis as a case	79
Exploring the regulatory role of mtTFA on inflammation, oxidative stress, and epigenetic alterations in COPD progressed NSCLC patients with smoking history	78
Endoglin promotes podocyte injury and apoptosis through the autophagy-lysosomal pathway in lupus nephritis	75
SERPINH1 secretion by cancer-associated fibroblasts promotes hepatocellular carcinoma malignancy through SENP3-mediated SP1/SQLE pathway	75
ADAM28 promotes epithelial mesenchymal transition and impairs tight junctions in non-eosinophilic chronic rhinosinusitis with nasal polyps by inducing M1 polarization of macrophages	75
Piperine inhibits fungal growth and protects against pyroptosis in Aspergillus fumigatus keratitis by regulating the mTOR/HIF-1α pathway	73
Establishment and validation of an immune-related genes diagnostic model and experimental validation of diagnostic biomarkers for autoimmune thyroiditis based on RNA-seq	70
SIRT6 attenuates calcium oxalate Nephrocalcinosis-induced renal inflammation and oxidative injury via activating NRF2 signaling	68
Efficacy and safety of anti-CD19 CAR-T in a mouse model of IgG4-related disease	68
Leveraging miRNA-mediated expression profiles to predict prognosis and identify distinct molecular subtypes in ovarian cancer: a multi-cohort study	68
RETRACTED: NUTM2A-AS1 silencing alleviates LPS-induced apoptosis and inflammation in dental pulp cells through targeting let-7c-5p/HMGB1 axis	68

Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress	66
VSIG4 induces the immunosuppressive microenvironment by promoting the infiltration of M2 macrophage and Tregs in clear cell renal cell carcinoma	65
Therapeutic vaccine targeting dual immune checkpoints induces potent multifunctional CD8+ T cell anti-tumor immunity	63
IGF2BP3 regulates macrophage-induced inflammation and liver damage in acute-on-chronic liver failure via the RORα-NF-κB signaling axis	62
Serum amyloid A1 induced dysfunction of airway macrophages via CD36 pathway in allergic airway inflammation	62
Antagonism of CD28 blocks allergic responses in the ovalbumin-induced asthmatic model mice	61
Protective effects of Gumibao recipe on glucocorticoid-included bone microcirculatory endothelial cell injury and the underlying mechanism	61
Wogonin attenuates neutrophilic inflammation and airway smooth muscle proliferation through inducing caspase-dependent apoptosis and inhibiting MAPK/Akt signaling in allergic airways	61
Post-COVID-19 sequelae are associated with sustained SARS-CoV-2-specific CD4+ immune responses	61
Elevated IL-15 levels in systemic lupus erythematosus: potential pathogenesis insight and therapeutic target	61
A comprehensive pan-cancer examination of transcription factor MAFF: Oncogenic potential, prognostic relevance, and immune landscape dynamics	60
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner	60
AGR, LMR and SIRI are the optimal combinations for risk stratification in advanced patients with non-small cell lung cancer following immune checkpoint blockers	59
Mustard lung with a unique oxidative stress profile as an independent pulmonary disease	59
FTO/miR-503-5p/USP10 axis regulates neuronal endoplasmic reticulum stress-mediated apoptosis in ischemic stroke	58
Exploring Isotretinoin’s Unexpected Acceleration of wound Healing: A rat model study	58
Betulin inhibits the production of inflammatory cytokines in human gingival fibroblasts and ligature-induced periodontitis	57
Neonatal heart tissue-derived EVs alleviate adult ischemic cardiac injury via regulating the function of macrophages and cardiac regeneration in murine models	57
OTUD4-mediated inhibition of YAP1 signaling pathway in ovarian cancer: Implications for macrophage polarization and recruitment	57
Leptin, NK cells, and the weight of immunity: Insights into obesity	56
Association of sulfur mustard toxicity with oxidant/antioxidant system in veterans: A meta-analysis of case-control studies	56
Role of macrophages in cardiac arrhythmias: Pathogenesis and therapeutic perspectives	55
Skin inflammation and lipid disorder induced by topical application of Mal f 1	55
House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP-1/IL-24 Signaling pathway in allergic rhinitis	55
Study progress of etiologic mechanisms of chronic prostatitis/chronic pelvic pain syndrome	54
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience	54
Activation of immune checkpoint OX40 inhibits HBV replication in a mouse model	54
The natural product-derived JM-9 alleviates high-fat diet-induced fatty liver in mice by targeting MD2	53