OOIR: Observatory of International Research

Papers

(The H4-Index of International Immunopharmacology is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
In-vitro and in-silico evaluation of rue herb for SARS-CoV-2 treatment	333
Unveiling the impact of Cancer-IgG on glioma: Insights into biological behavior and macrophage polarization dynamics	166
VX-509 (Decernotinib)-modified tolerogenic dendritic cells alleviate experimental autoimmune neuritis by promoting Th17/Treg rebalance	139
Editorial Board	133
Skin inflammation and lipid disorder induced by topical application of Mal f 1	125
A novel combination therapy using Dapagliflozin and Cycas media extract in experimentally induced diabetic wounds by targeting novel pathways in wound healing	122
PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer	118
Designing a predictive Framework: Immune-Related Gene-Based nomogram and prognostic model for kidney renal papillary cell carcinoma	115
Procyanidin B2 targeted CCR7 expression to inhibit the senescence-associated secretory phenotype through the NF-κB pathway to promote osteogenic differentiation of periodontal ligament stem cells in p	109
27-hydroxycholesterol roles in respiratory disease pathogenesis	108
Sunitinib attenuates reactive MDSCs enhancing anti-tumor immunity in HNSCC	107
Laterosporulin25: A probiotically produced, novel defensin-like bacteriocin and its immunogenic properties	106
Therapeutic potential of microglia-derived extracellular vesicles in ischemic stroke	103
Acertannin attenuates LPS-induced inflammation by interrupting the binding of LPS to the TLR4/MD2 complex and activating Nrf2-mediated HO-1 activation	100
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner	93
Activated intestinal microbiome-associated tryptophan metabolism upregulates aryl hydrocarbon receptor to promote osteoarthritis in a rat model	93
GRK2-facilitated TLR4 signaling promotes cardiac fibrosis in rheumatic mice	93
Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling	89
Single‑cell RNA sequencing reveals heterogeneity in ovarian cancer and constructs a prognostic signature for prognostic prediction and immunotherapy	89
Comprehensive analysis of MFN2 as a prognostic biomarker associated with immune cell infiltration in renal clear cell carcinoma	86
MCTR1 ameliorates LPS-induced lung injury by inhibiting neutrophil reverse transendothelial migration	85
Role of S100A1, S100A4, S100A8/A9 and S100B in myocardial infarction and heart failure	83
Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity: Therapeutic potential against SARS-CoV-2 (COVID-19)	81
Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-19	81
High-titer rheumatologic markers in serum of veterans with severe pulmonary complications 25–30 years after sulfur mustard exposure	81

“The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease”	79
Edaravone attenuates cerebral inflammation by inhibiting mast cells degranulation via ROS/STIM1 signaling pathway in HIE model	78
Macrophage-specific deletion of HO-1 aggravates radiation-induced lung injury through an PP2A-dependent manner	75
Multi-omics analysis reveals dynamic proteomic remodeling and metabonomic dysregulation underlying cytokine release syndrome in CAR-T-treated B-ALL	74
Safety and immunogenicity of the ChAdOx1, MVA-MERS-S, and GLS-5300 DNA MERS-CoV vaccines	72
Bovine serum albumin nanoparticles containing Poly (I:C) can enhance the neutralizing antibody response induced by envelope protein of Orthoflavivirus zikaense	71
Expression of extracellular HSP90α in pre- and post-treatment samples of driver-gene-negative non-small cell lung cancer	69
Editorial Board	69
Intravenous immunoglobulin therapy for HIV-associated Guillain–Barré syndrome	69
Facial palsy induced by immune checkpoint blockade: A systematic analysis of clinical trials and a pharmacovigilance study of postmarketing data	67
Using immune clusters for classifying Mycobacterium tuberculosis infection	67
SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome	67
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae	67
SRSF10 facilitates HCC growth and metastasis by suppressing CD8+T cell infiltration and targeting SRSF10 enhances anti-PD-L1 therapy	65
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress	65
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway	65
Curative effects of crocin in ulcerative colitis via modulating apoptosis and inflammation	65
Codelivery of triptolide and IFN-γ to boost antitumor immunity for triple-negative breast cancer	64
Pathological insights into activin A: Molecular underpinnings and therapeutic prospects in various diseases	63
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice	62
Dual-sensitive gelatin-coated chitosan microparticles for targeted semaglutide pulmonary delivery: a novel approach to enhancing anti-inflammatory and anti-fibrotic effects	61
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron	60
Comprehensive characteristics of pulmonary antineutrophil cytoplasmic antibody-associated vasculitis and the development of a predictive nomogram for mortality	60
Fut2 deficiency aggravates chronic colitis through 2-oxindole-AHR mediated cGAS-STING pathway	59
Pellino2 accelerate inflammation and pyroptosis via the ubiquitination and activation of NLRP3 inflammation in model of pediatric pneumonia	59
NY-ESO-1 in Triple-Negative Breast Cancer: Systematic Review, Meta-Analysis, and Immunotherapeutic Implications	59
Tumor microenvironment and immunometabolic reprogramming in pancreatic ductal adenocarcinoma: Barriers and breakthroughs in immunotherapy	59
Deletion of FAM76B histidine-rich region enhances macrophage-mediated osteosarcoma inhibition via liquid-liquid phase separation	59
Immunoregulatory kinases and T-cell pathways in DNA-damage response and autoimmune inflammation: Emerging roles of BUB1 and IGFL2	59
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience	59
Immunosenescence as a convergence pathway in neurodegeneration	58
CircMETTL14(11)S upregulated METTL14 and induced CXCR4 to aggravate endothelial inflammation and atherosclerosis	58
Profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin D3 treatment in the mice model of vascular dementia	58
Efficacy and safety of tofacitinib in the treatment of adults with lichen planopilaris: A randomized placebo-controlled trial	58