OOIR: Observatory of International Research

Papers

(The H4-Index of International Immunopharmacology is 54. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
In-vitro and in-silico evaluation of rue herb for SARS-CoV-2 treatment	269
Unveiling the impact of Cancer-IgG on glioma: Insights into biological behavior and macrophage polarization dynamics	161
Fut2 deficiency aggravates chronic colitis through 2-oxindole-AHR mediated cGAS-STING pathway	132
CD83 mediates the inhibitory effect of the S1PR1 agonist CYM5442 on LPS-induced M1 polarization of macrophages through the ERK-STAT-1 signaling pathway	119
VX-509 (Decernotinib)-modified tolerogenic dendritic cells alleviate experimental autoimmune neuritis by promoting Th17/Treg rebalance	116
Editorial Board	110
Deletion of BMP4 impairs trophoblast function and decidual macrophage polarization via autophagy leading to recurrent spontaneous abortion	109
Skin inflammation and lipid disorder induced by topical application of Mal f 1	108
Corrigendum to “Combined diosmin and bisoprolol attenuate cobalt chloride-induced cardiotoxicity and endothelial dysfunction through modulating miR-143-3P/MAPK/MCP-1, ERK5/CXCR4, Orai-1/STIM-1 signali	97
Dexmedetomidine therapy promotes cardiac dysfunction and increases mortality in sepsis: A translational study	93
A novel combination therapy using Dapagliflozin and Cycas media extract in experimentally induced diabetic wounds by targeting novel pathways in wound healing	90
Fibroblast growth factor 9 reduces TBHP-induced oxidative stress in chondrocytes and diminishes mouse osteoarthritis by activating ERK/Nrf2 signaling pathway	90
Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity: Therapeutic potential against SARS-CoV-2 (COVID-19)	89
Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-19	85
High-titer rheumatologic markers in serum of veterans with severe pulmonary complications 25–30 years after sulfur mustard exposure	84
Unveiling the interplay between hepatocyte SATB1 and innate immunity in autoimmune hepatitis	83
ILC2s control obesity by regulating energy homeostasis and browning of white fat	82
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization	82
Antagonism of CD28 blocks allergic responses in the ovalbumin-induced asthmatic model mice	80
PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer	75
Mechanism of Keke tablets in treating post-infectious cough following influenza A virus infection based on network pharmacology, molecular docking, molecular dynamics and in vivo experiments	72
Designing a predictive Framework: Immune-Related Gene-Based nomogram and prognostic model for kidney renal papillary cell carcinoma	72
Targeting the mechanism of IRF3 in sepsis-associated acute kidney injury via the Hippo pathway	71
Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling	71
Mmu_circ_0005373 and hsa_circ_0136255 participate in the pulmonary fibrosis of systemic sclerosis	71

Association of soluble PD-L1 and NLR combination with 1-Year mortality in patients with COVID-19	70
Single‑cell RNA sequencing reveals heterogeneity in ovarian cancer and constructs a prognostic signature for prognostic prediction and immunotherapy	70
Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages	69
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock	68
An overview of immune checkpoint therapy in autoimmune diseases	67
Bovine-derived α-lactalbumin exhibits cardiovascular protection against aging by ameliorating the inflammatory process in mice	67
Procyanidin B2 targeted CCR7 expression to inhibit the senescence-associated secretory phenotype through the NF-κB pathway to promote osteogenic differentiation of periodontal ligament stem cells in p	66
Efficacy and safety of moxibustion as a complementary and alternative therapy for asthma: A systematic review and meta-analysis	65
Acertannin attenuates LPS-induced inflammation by interrupting the binding of LPS to the TLR4/MD2 complex and activating Nrf2-mediated HO-1 activation	64
27-hydroxycholesterol roles in respiratory disease pathogenesis	64
Maclurin inhibits caspase-11 non-canonical inflammasome in macrophages and ameliorates acute lethal sepsis in mice	63
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury	63
GRK2-facilitated TLR4 signaling promotes cardiac fibrosis in rheumatic mice	63
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia ac	63
Kongensin a attenuates intervertebral disc degeneration by inhibiting TAK1-mediated PANoptosis of nucleus pulposus cells	60
Ginsenoside 20(R)-Rg3 enhances natural killer cell activity by increasing activating receptor expression through the MAPK/ERK signaling pathway	60
Plasma levels of 12 different cytokines correlate to PD-1 inhibitor combined chemotherapy responses in advanced non-small-cell lung cancer patient	58
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice	58
Inhibition of CRLF1 expression by miR-8485 alleviates IL-1β-induced chondrocyte inflammation, apoptosis, and extracellular matrix degradation	57
Tripartite motif containing 59 mediates protective anti-oxidative effects in intestinal injury through Nrf2 signaling	57
Mustard lung with a unique oxidative stress profile as an independent pulmonary disease	57
Macrophage crosstalk and therapies: Between tumor cells and immune cells	56
Expression of extracellular HSP90α in pre- and post-treatment samples of driver-gene-negative non-small cell lung cancer	56
Editorial Board	56
Highlights into historical and current immune interventions for cancer	55
Corrigendum to “Integrated population pharmacokinetics of immunoglobulin G following intravenous or subcutaneous administration of various immunoglobulin products in patients with primary immunodefici	55
Intravenous immunoglobulin therapy for HIV-associated Guillain–Barré syndrome	55
Profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin D3 treatment in the mice model of vascular dementia	54
Using immune clusters for classifying Mycobacterium tuberculosis infection	54
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae	54
Enrichment of innate immune cells from PBMC followed by triple cytokine activation for adoptive immunotherapy	54