International Immunopharmacology

Papers
(The TQCC of International Immunopharmacology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
In-vitro and in-silico evaluation of rue herb for SARS-CoV-2 treatment635
Unveiling the impact of Cancer-IgG on glioma: Insights into biological behavior and macrophage polarization dynamics243
Fut2 deficiency aggravates chronic colitis through 2-oxindole-AHR mediated cGAS-STING pathway160
C1q/TNF-related protein-9 promotes diabetic wound healing by enhancing dendritic cell efferocytosis via the ATF3/SLC7A11 signaling axis119
CD83 mediates the inhibitory effect of the S1PR1 agonist CYM5442 on LPS-induced M1 polarization of macrophages through the ERK-STAT-1 signaling pathway112
Role of S100A1, S100A4, S100A8/A9 and S100B in myocardial infarction and heart failure110
VX-509 (Decernotinib)-modified tolerogenic dendritic cells alleviate experimental autoimmune neuritis by promoting Th17/Treg rebalance105
Deletion of BMP4 impairs trophoblast function and decidual macrophage polarization via autophagy leading to recurrent spontaneous abortion103
Editorial Board103
Skin inflammation and lipid disorder induced by topical application of Mal f 197
Corrigendum to “Combined diosmin and bisoprolol attenuate cobalt chloride-induced cardiotoxicity and endothelial dysfunction through modulating miR-143-3P/MAPK/MCP-1, ERK5/CXCR4, Orai-1/STIM-1 signali87
Dexmedetomidine therapy promotes cardiac dysfunction and increases mortality in sepsis: A translational study86
Exosome-derived SLC12A2-DT promotes macrophage M2 polarization-mediated hepatocellular carcinoma progression86
A novel combination therapy using Dapagliflozin and Cycas media extract in experimentally induced diabetic wounds by targeting novel pathways in wound healing85
Quantitative analysis of immune cells within the tumor microenvironment of glioblastoma and their relevance for prognosis84
Exploring dysregulated immune response genes and endothelial dysfunction biomarkers as predictors of severe COVID-1984
Ferroptosis in organ fibrosis: Mechanisms and therapeutic approaches81
High-titer rheumatologic markers in serum of veterans with severe pulmonary complications 25–30 years after sulfur mustard exposure81
Antiproliferative and apoptotic effects of (1R*,12R*)-dolabella-4(16),7,10-triene-3,13-dione (CI-A) in oral cancer cells are mediated by oxidative stress and ERK activation80
“The effect of 48-weeks azithromycin therapy on levels of soluble biomarkers associated with HIV-associated chronic lung disease”80
Role of macrophages in cardiac arrhythmias: Pathogenesis and therapeutic perspectives79
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice77
Efficacy and safety of anti-CD19 CAR-T in a mouse model of IgG4-related disease70
Antitumor effect of invasive Lactobacillus plantarum delivering associated antigen gene sHSP between Trichinella spiralis and Lewis lung cancer cells69
Unravelling the role of Interleukin-12 in Neuroinflammatory mechanisms: Pathogenic pathways linking Neuroinflammation to neuropsychiatric disorders69
Molecular pathways and biological roles of melatonin and vitamin D; effects on immune system and oxidative stress67
Dual-sensitive gelatin-coated chitosan microparticles for targeted semaglutide pulmonary delivery: a novel approach to enhancing anti-inflammatory and anti-fibrotic effects66
27-hydroxycholesterol roles in respiratory disease pathogenesis64
Cyclic helix B peptide alleviates liver fibrosis via attenuating ROS-mediated pyroptosis64
LXA4 attenuates perioperative neurocognitive disorders by suppressing neuroinflammation and oxidative stress63
The role of cGAS-STING signaling pathway in colorectal cancer immunotherapy: Mechanism and progress63
An “On Demand” canakinumab regimen for treating children with Colchicine-Resistant familial Mediterranean fever – A multicentre study62
Procyanidin B2 targeted CCR7 expression to inhibit the senescence-associated secretory phenotype through the NF-κB pathway to promote osteogenic differentiation of periodontal ligament stem cells in p62
The role of lncRNA and miRNA on the effects of occurrence and development of osteosarcoma62
IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry61
VX765 alleviates dextran sulfate sodium-induced colitis in mice by suppressing caspase-1-mediated pyroptosis61
Solubilized curcuminoid complex prevents extensive immunosuppression through immune restoration and antioxidant activity: Therapeutic potential against SARS-CoV-2 (COVID-19)61
VSIG4 induces the immunosuppressive microenvironment by promoting the infiltration of M2 macrophage and Tregs in clear cell renal cell carcinoma61
Macrophage-derived GSDMD promotes abdominal aortic aneurysm and aortic smooth muscle cells pyroptosis61
Efficacy and safety of tofacitinib in the treatment of adults with lichen planopilaris: A randomized placebo-controlled trial60
Review of the effects and Mechanisms of microglial autophagy in ischemic stroke60
Association between γδ T cells and clinicopathological features of breast cancer59
Intervention of neuroinflammation in the traumatic brain injury trajectory: In vivo and clinical approaches58
GDF11 alleviates spinal cord injury in rats by modulating microglia polarization through Smad2/3 and MAPK/NFκB signaling pathways58
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron58
Comprehensive transcriptomic analyses identify the immunosuppressive effects of LLDT-8 in ART-treated SIV-infected rhesus macaques58
Clinical evidence for the prognostic impact of metformin in cancer patients treated with immune checkpoint inhibitors57
Sunitinib attenuates reactive MDSCs enhancing anti-tumor immunity in HNSCC55
ILC2s control obesity by regulating energy homeostasis and browning of white fat55
The impact of long-term oral exposure to low doses of acrylamide on the hematological indicators, immune functions, and splenic tissue architecture in rats54
An overview of immune checkpoint therapy in autoimmune diseases53
Disulfiram attenuates MCMV-Induced pneumonia by inhibition of NF-κB/NLRP3 signaling pathway in immunocompromised mice53
Codelivery of triptolide and IFN-γ to boost antitumor immunity for triple-negative breast cancer53
Comprehensive analysis of a pyroptosis-related gene signature of clinical and biological value in acute myeloid leukaemia53
Impact of inflammation and anti-inflammatory modalities on diabetic cardiomyopathy healing: From fundamental research to therapy53
Hypoxia-induced Semaphorin 3A promotes the development of endometriosis through regulating macrophage polarization53
PD1-TLR10 fusion protein enhances the antitumor efficacy of CAR-T cells in colon cancer52
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages52
Antagonism of CD28 blocks allergic responses in the ovalbumin-induced asthmatic model mice52
Fisetin alleviates cerebral ischemia/reperfusion injury by regulating Sirt1/Foxc1/Ubqln1 pathway-mediated proteostasis52
Ex vivo pembrolizumab pharmacology for personalized PD-1 inhibitor therapy reveals a critical gap between receptor occupancy and T cell functionality52
Treatment with sitagliptin exacerbates the M2 phenotype in macrophages in vitro52
Exploring the regulatory role of mtTFA on inflammation, oxidative stress, and epigenetic alterations in COPD progressed NSCLC patients with smoking history51
Designing a predictive Framework: Immune-Related Gene-Based nomogram and prognostic model for kidney renal papillary cell carcinoma51
Farrerol alleviates cognitive impairments in chronic cerebral hypoperfusion via suppressing NLRP3 inflammasome-mediated pyroptosis51
Combined dupilumab with immunotherapy is more effective than dupilumab alone in children with moderate-to-severe atopic dermatitis50
Berberine sensitizes immune checkpoint blockade therapy in melanoma by NQO1 inhibition and ROS activation50
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: An add-on to its anti-dementia ac50
Kongensin a attenuates intervertebral disc degeneration by inhibiting TAK1-mediated PANoptosis of nucleus pulposus cells50
Mechanism of Keke tablets in treating post-infectious cough following influenza A virus infection based on network pharmacology, molecular docking, molecular dynamics and in vivo experiments50
Deletion of FAM76B histidine-rich region enhances macrophage-mediated osteosarcoma inhibition via liquid-liquid phase separation50
MultiOmics analysis of metabolic dysregulation and immune features in breast cancer50
Spermidine attenuates monocrotaline-induced pulmonary arterial hypertension in rats by inhibiting purine metabolism and polyamine synthesis-associated vascular remodeling49
GRK2-facilitated TLR4 signaling promotes cardiac fibrosis in rheumatic mice49
Mmu_circ_0005373 and hsa_circ_0136255 participate in the pulmonary fibrosis of systemic sclerosis49
Extracellular vesicles of ADSCs inhibit ischemic stroke-induced pyroptosis through Gbp3 regulation: A role for the NLRP3/GSDMD signaling pathway49
Targeting the mechanism of IRF3 in sepsis-associated acute kidney injury via the Hippo pathway49
Identification of TAP1 as a T-cell related therapeutic target in gastric cancer by mediating oxalipliatin-related synergistic enhancement of immunotherapy48
Association of soluble PD-L1 and NLR combination with 1-Year mortality in patients with COVID-1948
Hydrogen-rich saline regulates NLRP3 inflammasome activation in sepsis-associated encephalopathy rat model48
Single‑cell RNA sequencing reveals heterogeneity in ovarian cancer and constructs a prognostic signature for prognostic prediction and immunotherapy48
Edaravone attenuates cerebral inflammation by inhibiting mast cells degranulation via ROS/STIM1 signaling pathway in HIE model48
Inhibition of CRLF1 expression by miR-8485 alleviates IL-1β-induced chondrocyte inflammation, apoptosis, and extracellular matrix degradation47
Unveiling the interplay between hepatocyte SATB1 and innate immunity in autoimmune hepatitis47
Tacrolimus alleviates pulmonary fibrosis progression through inhibiting the activation and interaction of ILC2 and monocytes47
Natural bioactive compounds reprogram bile acid metabolism in MAFLD: Multi-target mechanisms and therapeutic implications47
Long-term outcomes in patients with persistent EBV-DNA positivity after primary Epstein-Barr virus infection and clinical implications of rituximab therapy47
SO2 activates Th17 cells through the JAK1,2/STAT3 signaling pathway47
Maclurin inhibits caspase-11 non-canonical inflammasome in macrophages and ameliorates acute lethal sepsis in mice47
METTL3-mediated m6A modification of CD36: Implications for glucose metabolism and inflammatory dysregulation in follicles of polycystic ovary syndrome46
C1632 protects against LPS-induced acute lung injury by regulating AXL-mediated MAPK/NF-κB signaling pathway45
Revealing rutaecarpine’s promise: A pathway to parkinson’s disease relief through PPAR modulation45
Expression of extracellular HSP90α in pre- and post-treatment samples of driver-gene-negative non-small cell lung cancer45
Exploration and Validation of Ferroptosis-Associated Genes in ADAR1 Deletion-Induced NAFLD through RNA-seq Analysis45
Comprehensive characteristics of pulmonary antineutrophil cytoplasmic antibody-associated vasculitis and the development of a predictive nomogram for mortality45
Editorial Board45
Macrophage crosstalk and therapies: Between tumor cells and immune cells45
CircMETTL14(11)S upregulated METTL14 and induced CXCR4 to aggravate endothelial inflammation and atherosclerosis44
Bovine serum albumin nanoparticles containing Poly (I:C) can enhance the neutralizing antibody response induced by envelope protein of Orthoflavivirus zikaense44
Lactic acid, a driver of tumor-stroma interactions44
SRSF10 facilitates HCC growth and metastasis by suppressing CD8+T cell infiltration and targeting SRSF10 enhances anti-PD-L1 therapy44
T-cell immunoglobulin and mucin-domain containing-3 (TIM-3): Solving a key puzzle in autoimmune diseases44
Pathological insights into activin A: Molecular underpinnings and therapeutic prospects in various diseases44
Ergothioneine inhibits the progression of osteoarthritis via the Sirt6/NF-κB axis both in vitro and in vivo44
Controversial role of γδ T cells in pancreatic cancer44
The E3 ubiquitin ligase RNF31 mediates the development of ulcerative colitis by regulating NLRP3 inflammasome activation43
Tripartite motif containing 59 mediates protective anti-oxidative effects in intestinal injury through Nrf2 signaling43
Exosomal circRNA-001264 promotes AML immunosuppression through induction of M2-like macrophages and PD-L1 overexpression43
Fecal microbiota transplantation affects the recovery of AD-skin lesions and enhances gut microbiota homeostasis43
Toll-like receptor 2 deficiency ameliorates obesity-induced cardiomyopathy via inhibiting NF-κB signaling pathway43
Single-cell RNA sequencing reveals the impact of mechanical loading on knee tibial cartilage in osteoarthritis43
SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome42
Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options42
Sinomenine promotes flap survival by upregulating eNOS and eNOS-mediated autophagy via PI3K/AKT pathway42
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae42
Profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin D3 treatment in the mice model of vascular dementia42
Posttreatment with dexmedetomidine aggravates LPS-induced myocardial dysfunction partly via activating cardiac endothelial α2A-AR in mice42
Carbon monoxide-releasing molecule 2 inhibits inflammation associated with intestinal ischemia-reperfusion injury in a rat model of hemorrhagic shock42
Using immune clusters for classifying Mycobacterium tuberculosis infection42
Acupressure bladder meridian alleviates anxiety disorder via HMGB142
Single-Cell RNA sequencing highlights the regulatory role of T cell marker genes Ctla4, Ccl5 and Tcf7 in corneal allograft rejection of mouse model42
Activation of NLRP3 inflammasome contributes to the inflammatory response to allergic rhinitis via macrophage pyroptosis41
Pentosan Polysulfate Sodium augments the therapeutic effect of 5-Aminosalicylic Acid in DSS colitis model; the role of IL-35 expression41
Arctigenin mitigates insulin resistance by modulating the IRS2/GLUT4 pathway via TLR4 in type 2 diabetes mellitus mice41
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma41
Comprehensive analysis of MFN2 as a prognostic biomarker associated with immune cell infiltration in renal clear cell carcinoma41
Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages41
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing41
Corrigendum to “Integrated population pharmacokinetics of immunoglobulin G following intravenous or subcutaneous administration of various immunoglobulin products in patients with primary immunodefici41
Effects of RETN polymorphisms on treatment response in rheumatoid arthritis patients receiving TNF-α inhibitors and utilization of machine-learning algorithms41
Activated intestinal microbiome-associated tryptophan metabolism upregulates aryl hydrocarbon receptor to promote osteoarthritis in a rat model40
MicroRNA-155 and antiviral immune responses40
Clinical relevance of Alternaria alternata sensitization in patients within type 2-high and type 2-low asthma40
Safety and immunogenicity of the ChAdOx1, MVA-MERS-S, and GLS-5300 DNA MERS-CoV vaccines40
Pellino2 accelerate inflammation and pyroptosis via the ubiquitination and activation of NLRP3 inflammation in model of pediatric pneumonia40
Retraction notice to “BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice” [Int. Immunopharmacol. 93 (2021) 107389]40
The innate immune sensor STING accelerates neointima formation via NF-κB signaling pathway40
Highlights into historical and current immune interventions for cancer40
Ginsenoside 20(R)-Rg3 enhances natural killer cell activity by increasing activating receptor expression through the MAPK/ERK signaling pathway40
Enrichment of innate immune cells from PBMC followed by triple cytokine activation for adoptive immunotherapy40
Acertannin attenuates LPS-induced inflammation by interrupting the binding of LPS to the TLR4/MD2 complex and activating Nrf2-mediated HO-1 activation40
Fibroblast growth factor 9 reduces TBHP-induced oxidative stress in chondrocytes and diminishes mouse osteoarthritis by activating ERK/Nrf2 signaling pathway39
Combinatorial in silico and in vivo evaluation of immune response elicitation by the affibody ZHER239
Lack of lymphocytes exacerbate heat stroke severity in male mice through enhanced inflammatory response38
Cuproptosis-related gene PDHX and heat stress-related HSPD1 as potential key drivers associated with cell stemness, aberrant metabolism and immunosuppression in esophageal carcinoma38
2′, 4′-Dihydroxy-2,3-dimethoxychalcone: A pharmacological inverse agonist of RORγt ameliorating Th17-driven inflammatory diseases by regulating Th17/Treg38
Bomidin attenuates inflammation of periodontal ligament stem cells and periodontitis in mice via inhibiting ferroptosis38
Towards exertion of immunotherapeutics in the treatment of colorectal cancer; adverse sides, challenges, and future directions38
Advances in the application of immune checkpoint inhibitors in gynecological tumors38
Prophylaxis strategies containing high dose intravenous methotrexate on preventing CNS relapse for patients with diffuse large B-cell lymphoma at intermediate to high risk: A study based on 12 cohorts38
Clinical features and prognostic factors of severe cutaneous adverse drug reactions: A single-center retrospective study of 209 cases in China38
Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway38
Intravenous immunoglobulin therapy for HIV-associated Guillain–Barré syndrome38
CXCL1 enhances COX-II expression in rheumatoid arthritis synovial fibroblasts by CXCR2, PLC, PKC, and NF-κB signal pathway38
Facial palsy induced by immune checkpoint blockade: A systematic analysis of clinical trials and a pharmacovigilance study of postmarketing data37
Hesperetin alleviates PM2.5-induced lung injury by inhibiting ferroptosis in an Nrf2-dependent manner37
Efficacy and safety of moxibustion as a complementary and alternative therapy for asthma: A systematic review and meta-analysis37
Neuronal ferroptosis and ferroptosis-mediated endoplasmic reticulum stress: Implications in cognitive dysfunction induced by chronic intermittent hypoxia in mice37
Plasma levels of 12 different cytokines correlate to PD-1 inhibitor combined chemotherapy responses in advanced non-small-cell lung cancer patient37
SAP130 released by ferroptosis tubular epithelial cells promotes macrophage polarization via Mincle signaling in sepsis acute kidney injury37
Therapeutic potential of microglia-derived extracellular vesicles in ischemic stroke37
Dietary capsaicin attenuates cardiac injury after myocardial infarction in type 2 diabetic mice by inhibiting ferroptosis through activation of TRPV1 and Nrf2/HMOX1 pathway37
Laterosporulin25: A probiotically produced, novel defensin-like bacteriocin and its immunogenic properties37
Toll-like receptor 4 deficiency affects the balance of osteoclastogenesis and osteoblastogenesis in periodontitis37
Mustard lung with a unique oxidative stress profile as an independent pulmonary disease37
SERPINH1 secretion by cancer-associated fibroblasts promotes hepatocellular carcinoma malignancy through SENP3-mediated SP1/SQLE pathway37
MCTR1 ameliorates LPS-induced lung injury by inhibiting neutrophil reverse transendothelial migration37
Immune system roles in pathogenesis, prognosis, control, and treatment of Toxoplasma gondii infection36
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience36
Leonurine attenuates OVA-induced asthma via p38 MAPK/NF-κB signaling pathway36
Bovine-derived α-lactalbumin exhibits cardiovascular protection against aging by ameliorating the inflammatory process in mice36
Fibroblast growth factor 21 mitigates lupus nephritis progression via the FGF21/Irgm 1/NLRP3 inflammasome pathway36
Immunosenescence as a convergence pathway in neurodegeneration36
Dapagliflozin alleviated seizures and cognition impairment in pilocarpine induced status epilepticus via suppressing microglia-mediated neuroinflammation and oxidative stress36
The roles of orphan nuclear receptor 4 group A1 and A2 in fibrosis36
Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats36
NOX4 regulates gastric cancer cell invasion and proliferation by increasing ferroptosis sensitivity through regulating ROS35
Lactic acid-induced M2-like macrophages facilitate tumor cell migration and invasion via the GPNMB/CD44 axis in oral squamous cell carcinoma35
ALKBH5 controlled autophagy of peripheral blood mononuclear cells by regulating NRG1 mRNA stability in ankylosing spondylitis35
Calcitonin gene-related peptide-modulated macrophage phenotypic alteration regulates angiogenesis in early bone healing35
SCD1 protects acinar cells from ferroptosis during severe acute pancreatitis by balancing lipid and redox homeostasis35
Curative effects of crocin in ulcerative colitis via modulating apoptosis and inflammation35
Membranous nephropathy: Mechanistic insights and therapeutic perspectives35
AdipoRon exerts an antidepressant effect by inhibiting NLRP3 inflammasome activation in microglia via promoting mitophagy35
Editorial Board35
Changes in the phenotype and function of mucosal-associated invariant T cells in neutrophilic asthma35
Tetrandrine alleviates atherosclerosis via inhibition of STING-TBK1 pathway and inflammation in macrophages35
Distinct inflammatory profiles in mustard lung: A study of sulfur mustard-exposed patients with serious pulmonary complications35
Butyrate alleviates alcoholic liver disease-associated inflammation through macrophage regulation and polarization via the HDAC1/miR-155 axis35
Haemolysis is a concerning bias in some ozone therapy approaches35
C/EBP β/AEP pathway mediates hippocampal mitochondrial damage in a mouse model of sepsis encephalopathy34
Corydaline attenuates osteolysis in rheumatoid arthritis via mitigating reactive oxygen species production and suppressing calcineurin-Nfatc1 signaling34
Phosphodiesterase 4D protects against embryo loss via KLF4-IFITM3 axis during viral infection34
Inhibition of CTSC contributes to psoriasis inflammation and keratinocyte hyperproliferation by NF-κB signaling pathway34
The activation of cGAS-STING pathway promotes the epithelial-mesenchymal transition and inflammation in intrauterine adhesion34
METTL3-mediated MSRB3 m6A modification accelerates hypoxia-induced cardiomyocyte ferroptosis by inhibiting mitochondrial oxidative phosphorylation34
Interferon regulatory factor 5 attenuates kidney fibrosis through transcriptional suppression of Tgfbr134
Corrigendum to “High glucose intake exacerbates experimental autoimmune prostatitis through mitochondrial reactive oxygen species-dependent TGF-β activation-mediated Th17 differentiation” [Int. Immuno34
Engineered macrophages in breast Cancer: bridging targeted therapy and advanced drug delivery34
Interleukin 8 exacerbates age-related hearing loss through regulating perivascular-resident macrophage-like melanocytes viability and the permeability of the endothelial cells34
Combining ulinastatin with TIENAM improves the outcome of sepsis induced by cecal ligation and puncture in mice by reducing inflammation and regulating immune responses34
Understanding the relationship between silicone implants, tumor antigens, and breast cancer risk: An immunological study in rats34
Corrigendum to “Downregulation of S100A11 promotes T cell infiltration by regulating cancer-associated fibroblasts in prostate cancer” [Int. Immunopharmacol. 128 (2024) 111323]34
SZ168 alleviates bleomycin-induced pulmonary fibrosis by inhibiting podoplanin-induced platelet activation34
Novel neuroglobin boosters as a therapeutic strategy for traumatic brain injury34
Peficitinib ameliorates doxorubicin-induced cardiotoxicity by suppressing cellular senescence and enhances its antitumor activity34
IRG1/Itaconate inhibits hepatic stellate cells ferroptosis and attenuates TAA-induced liver fibrosis by regulating SLC39A14 expression33
Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt333
Oleoylethanolamide exerts neuroprotection following ischemic stroke through microglial PPARα signal33
A novel blood-based bioassay to monitor adiponectin signaling33
Schisandrin B inhibits inflammation and ferroptosis in S.aureus-induced mastitis through regulating SIRT1/p53/SLC7A11 signaling pathway33
5-aminolaevulinic acid with sodium ferrous citrate alleviated kidney injury and fibrosis in a unilateral ureteral obstruction model33
Corrigendum to “Attenuated Salmonella carrying siRNA-CD24 improved the effect of oxaliplatin on HCC” [Int. Immunopharmacol. 124 (2023) 111025].32
EGR2 promotes liver cancer metastasis by enhancing IL-8 expression through transcription regulation of PDK4 in M2 macrophages32
Silencing of activating transcription factor 3 alleviates oxidative stress and inflammation and improves cognitive dysfunction in vascular dementia rats by repressing ferroptosis32
Unveiling the mystery of ILC3s: Their functions and interactions in mucosal immunity32
Immune checkpoints in B-cell Lymphoma: Still an Unmet challenge from Basic research to clinical practice32
Corrigendum to “Spirulina platensis shields the submandibular gland from cadmium toxicity by bolstering antioxidant defenses and maintaining its structural integrity” [Int. Immunopharmacol. 25 (2024) 32
Beyond Genes: Epiregulomes as Molecular Commanders in Innate Immunity32
Research progress on the mechanism of antidepressant effect of salidroside32
Traumatic brain Injury: Comprehensive overview from pathophysiology to Mesenchymal stem Cell-Based therapies32
Cannabidiol suppresses silica-induced pulmonary inflammation and fibrosis through regulating NLRP3/TGF-β1/Smad2/3 pathway31
Canagliflozin inhibits hepatic stellate cells activation and proliferation by inhibiting PP2A-mediated β-catenin dephosphorylation to attenuate hepatic fibrosis31
KLF6 enhances ferroptosis in S-AKI through the NCOA4/ACSL4/LPCAT3 axis31
Incidence of thyroid dysfunction caused by immune checkpoint inhibitors combined with chemotherapy: A systematic review and meta-analysis31
Neuroinflammation to neurodegeneration: Boulevard of broken nerves31
The antidepressant effect of resveratrol may correlate with the anti-inflammatory pathways mediated by Tas2r123 in hippocampus31
Genetic association of tertiary lymphoid structure-related gene signatures with HCC based on Mendelian randomization and machine learning and construction of prognosis model31
Aptamers as immune checkpoint inhibitors in cancer immunotherapy: targeting CTLA-4/B7 and PD-1/PD-L1 pathways31
Immunomodulatory roles of autophagic flux and IFIT in human ectocervical cells upon Trichomonas vaginalis infection31
Polysaccharides from Dicliptera chinensis (L.) Juss. Attenuates drug-induced liver injury by phosphorylating AMPK and thus facilitating the entry of FOXO3 into the cell nucleus31
Corrigendum to “Advances and challenges in the development of periodontitis vaccines: A comprehensive review” [Int. Immunopharmacol. 140 (2024) 112650]31
rBet v 1a-BanLec induce upregulation of IL-10 and IFN-γ gene expression in Caco-2/THP-1 co-culture and secretion of IL-10 and IFN-γ/IL-4 levels in PBMCs of birch pollen allergic donors31
Human umbilical cord-derived mesenchymal stromal cells alleviate liver cirrhosis through the Hippo/YAP/Id1 pathway and macrophage-dependent mechanism31
Macrophage-mediated activation of the IL4I1/AhR axis is a key player in allergic rhinitis31
Amlodipine and perindopril modulate miR-874-3p expression to regulate ferroptosis-linked LPCAT3/LACS4/GPX4 Axis and gut dysbiosis in metabolic-associated steatohepatitis31
Novel analgesic peptide derived from Cinobufacini injection suppressing inflammation and pain via ERK1/2/COX-2 pathway31
SHP-1 alleviates acute liver injury caused by Escherichia coli sepsis through negatively regulating the canonical and non-canonical NFκB signaling pathways31
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway31
Upregulation of LSP1 in AML cells enhances AML resistance to sorafenib and promotes apoptosis in CD8+ T cells30
Plumbagin improves myocardial fibrosis after myocardial infarction by inhibiting the AKT/mTOR pathway to upregulate autophagy levels30
Tet2 modulates M2 macrophage polarization via mRNA 5-methylcytosine in allergic rhinitis30
Edaravone alleviates methotrexate-induced testicular injury in rats: Implications on inflammation, steroidogenesis, and Akt/p53 signaling30
Protective effects of BTK inhibition by acalabrutinib on cisplatin-induced renal and testicular injury in mice: Modulation of mTOR/AMPK, NLRP3/GSDMD-N, and apoptotic pathways.30
Exploration of the shared diagnostic genes and mechanisms between periodontitis and primary Sjögren’s syndrome by integrated comprehensive bioinformatics analysis and machine learning30
Eucalyptol, limonene and pinene enteric capsules attenuate airway inflammation and obstruction in lipopolysaccharide-induced chronic bronchitis rat model via TLR4 signaling inhibition30
5-Aminolaevulinic acid-based photodynamic therapy suppresses lipid secretion by inducing mitochondrial stress and oxidative damage in sebocytes and ameliorates ear acne in mice30
Precision medicine for severe asthma – Biological targeted therapy30
Myeloid-derived suppressor cells in cancer: Current knowledge and future perspectives30
Peptidomic profiling of mesenchymal stem cell-derived extracellular vesicles and anti-inflammatory activity of degraded peptides30
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