International Immunopharmacology

Article	Citations
The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients	633
Breast cancer: Biology, biomarkers, and treatments	319
MCP-1: Function, regulation, and involvement in disease	306
COVID-19 vaccine hesitancy and related fears and anxiety	231
Effect of gut microbiota on LPS-induced acute lung injury by regulating the TLR4/NF-kB signaling pathway	200
Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients	181
Effects of immune cells and cytokines on inflammation and immunosuppression in the tumor microenvironment	161
Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes	158
Interferon β-1b in treatment of severe COVID-19: A randomized clinical trial	136
Neutrophils and COVID-19: The road so far	124
Use of Machine Learning and Artificial Intelligence to predict SARS-CoV-2 infection from Full Blood Counts in a population	123
Baricitinib, a drug with potential effect to prevent SARS-COV-2 from entering target cells and control cytokine storm induced by COVID-19	119
Towards treatment planning of COVID-19: Rationale and hypothesis for the use of multiple immunosuppressive agents: Anti-antibodies, immunoglobulins, and corticosteroids	118
Hybridoma technology a versatile method for isolation of monoclonal antibodies, its applicability across species, limitations, advancement and future perspectives	117
Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets	107
Neutrophil Extracellular Traps (NETs) and Covid-19: A new frontiers for therapeutic modality	106
The roles of macrophage polarization in the host immune response to sepsis	100
The possible of immunotherapy for COVID-19: A systematic review	97
Clinical and laboratory features of COVID-19: Predictors of severe prognosis	91
Dimethyl fumarate improves cognitive deficits in chronic cerebral hypoperfusion rats by alleviating inflammation, oxidative stress, and ferroptosis via NRF2/ARE/NF-κB signal pathway	91
The WHO International Standard for COVID-19 serological tests: towards harmonization of anti-spike assays	89
COVID-19 and cancer: From basic mechanisms to vaccine development using nanotechnology	89
Mechanisms of immune escape in the cancer immune cycle	88
Fibroblast-like synoviocytes in rheumatoid arthritis: Surface markers and phenotypes	86
SARS-Cov-2 infection: Response of human immune system and possible implications for the rapid test and treatment	80

TIM-3: An update on immunotherapy	78
Abscopal effect in radioimmunotherapy	78
Stigmasterol protects rats from collagen induced arthritis by inhibiting proinflammatory cytokines	75
Pharmacological approaches to mitigate neuroinflammation in Alzheimer’s disease	75
Bradykinin receptors: Agonists, antagonists, expression, signaling, and adaptation to sustained stimulation	73
Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses	73
Damage-associated molecular patterns in tumor radiotherapy	72
Novel serological biomarkers for inflammation in predicting disease severity in patients with COVID-19	72
Ferrostatin-1 alleviates angiotensin II (Ang II)- induced inflammation and ferroptosis in astrocytes	71
The role of chemokines and chemokine receptors in multiple sclerosis	70
IFN regulatory Factor-1 induced macrophage pyroptosis by modulating m6A modification of circ_0029589 in patients with acute coronary syndrome	70
The deregulated immune reaction and cytokines release storm (CRS) in COVID-19 disease	70
Acute and post-acute phase of COVID-19: Analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC	69
Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats	68
A focused review on technologies, mechanisms, safety, and efficacy of available COVID-19 vaccines	67
microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation	63
The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection	62
Autoimmune phenomena following SARS-CoV-2 vaccination	61
Clostridium butyricum modulates gut microbiota and reduces colitis associated colon cancer in mice	60
Identification of immune-related lncRNA signature for predicting immune checkpoint blockade and prognosis in hepatocellular carcinoma	60
Predictive value of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in non-small cell lung cancer patients treated with immune checkpoint inhibitors: A meta-analysis	60
Tocilizumab for treatment patients with COVID-19: Recommended medication for novel disease	58
Luteolin inhibits autophagy in allergic asthma by activating PI3K/Akt/mTOR signaling and inhibiting Beclin-1-PI3KC3 complex	57
Ginsenoside Rg1 prevent and treat inflammatory diseases: A review	57
Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach	56
Subcutaneous administration of interferon beta-1a for COVID-19: A non-controlled prospective trial	56
Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats	54
Prognostic value and immunological role of PDCD1 gene in pan-cancer	54
Long noncoding RNA GAS5 promotes microglial inflammatory response in Parkinson's disease by regulating NLRP3 pathway through sponging miR-223-3p	54
The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19	54
Evaluating the effects of Intravenous Immunoglobulin (IVIg) on the management of severe COVID-19 cases: A randomized controlled trial	53
Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview	52
Potential role of interferons in treating COVID-19 patients	52
Natural compounds flavonoids as modulators of inflammasomes in chronic diseases	52
The covalent NLRP3-inflammasome inhibitor Oridonin relieves myocardial infarction induced myocardial fibrosis and cardiac remodeling in mice	51
The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway	51
RBM4 regulates M1 macrophages polarization through targeting STAT1-mediated glycolysis	51
Immunotherapeutic approaches to curtail COVID-19	51
Geniposide inhibits NLRP3 inflammasome activation via autophagy in BV-2 microglial cells exposed to oxygen–glucose deprivation/reoxygenation	51
Piezo1 activates the NLRP3 inflammasome in nucleus pulposus cell-mediated by Ca2+/NF-κB pathway	50
Bacteroides thetaiotaomicron relieves colon inflammation by activating aryl hydrocarbon receptor and modulating CD4+T cell homeostasis	50
Immune-related adverse events associated with immune checkpoint inhibitors: An updated comprehensive disproportionality analysis of the FDA adverse event reporting system	50
Role of pyroptosis in liver diseases	50
Administration of COVID-19 vaccines in immunocompromised patients	50
Adverse events following COVID-19 vaccination: A systematic review and meta-analysis	50
Immunotherapy of Cancer by Targeting Regulatory T cells	49
Quantity does not equal quality: Scientific principles cannot be sacrificed	49
Celastrol inhibits rheumatoid arthritis through the ROS-NF-κB-NLRP3 inflammasome axis	49
Development of a macrophages-related 4-gene signature and nomogram for the overall survival prediction of hepatocellular carcinoma based on WGCNA and LASSO algorithm	48
Immune and bioinformatics identification of T cell and B cell epitopes in the protein structure of SARS-CoV-2: A systematic review	48

The interactions and communications in tumor resistance to radiotherapy: Therapy perspectives	47
Identification and verification of an immune-related lncRNA signature for predicting the prognosis of patients with bladder cancer	47
Anemoside B4 prevents acute ulcerative colitis through inhibiting of TLR4/NF-κB/MAPK signaling pathway	47
Pinocembrin inhibited cardiomyocyte pyroptosis against doxorubicin-induced cardiac dysfunction via regulating Nrf2/Sirt3 signaling pathway	46
Ginsenoside Rk3 alleviated DSS-induced ulcerative colitis by protecting colon barrier and inhibiting NLRP3 inflammasome pathway	46
Melatonin attenuates LPS-induced pyroptosis in acute lung injury by inhibiting NLRP3-GSDMD pathway via activating Nrf2/HO-1 signaling axis	46
Roles of TGF-β signaling pathway in tumor microenvirionment and cancer therapy	45
Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 macrophages	45
LncRNA MIAT correlates with immune infiltrates and drug reactions in hepatocellular carcinoma	45
Safety and efficacy of Favipiravir in moderate to severe SARS-CoV-2 pneumonia	45
Muscone relieves inflammatory pain by inhibiting microglial activation-mediated inflammatory response via abrogation of the NOX4/JAK2-STAT3 pathway and NLRP3 inflammasome	45
Anti-rheumatoid arthritis effects of flavonoids from Daphne genkwa	45
Exosome-mediated miR-33 transfer induces M1 polarization in mouse macrophages and exerts antitumor effect in 4T1 breast cancer cell line	44
Ginsenoside Rg3 attenuates angiotensin II-induced myocardial hypertrophy through repressing NLRP3 inflammasome and oxidative stress via modulating SIRT1/NF-κB pathway	44
A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein	44
Drug repurposing and cytokine management in response to COVID-19: A review	44
LncRNA-Meg3 promotes Nlrp3-mediated microglial inflammation by targeting miR-7a-5p	44
An update on colorectal cancer microenvironment, epigenetic and immunotherapy	44
Breast cancer immunotherapy: Current and novel approaches	44
Low-intensity pulsed ultrasound promotes osteoarthritic cartilage regeneration by BMSC-derived exosomes via modulating the NF-κB signaling pathway	43
The potential for Lactoferrin to reduce SARS-CoV-2 induced cytokine storm	43
Synergistic cardioptotection by tilianin and syringin in diabetic cardiomyopathy involves interaction of TLR4/NF-κB/NLRP3 and PGC1a/SIRT3 pathways	43
Oxygen-ozone (O2-O3) immunoceutical therapy for patients with COVID-19. Preliminary evidence reported	43
Low-dose naltrexone inhibits colorectal cancer progression and promotes apoptosis by increasing M1-type macrophages and activating the Bax/Bcl-2/caspase-3/PARP pathway	42
Human umbilical cord mesenchymal stem cells-derived exosomal microRNA-17-3p ameliorates inflammatory reaction and antioxidant injury of mice with diabetic retinopathy via targeting STAT1	42
The interactions of paclitaxel with tumour microenvironment	42
Puerarin protects against myocardial ischemia/reperfusion injury by inhibiting inflammation and the NLRP3 inflammasome: The role of the SIRT1/NF-κB pathway	42
Diagnostic utility of C-reactive protein to albumin ratio as an early warning sign in hospitalized severe COVID-19 patients	41
Disulfidptosis classification of hepatocellular carcinoma reveals correlation with clinical prognosis and immune profile	41
Hydrogen gas alleviates blood-brain barrier impairment and cognitive dysfunction of septic mice in an Nrf2-dependent pathway	41
The therapeutic potential of resveratrol in a mouse model of melanoma lung metastasis	41
A possible pathogenic role of Syndecan-1 in the pathogenesis of coronavirus disease 2019 (COVID-19)	41
Antibiotic administration shortly before or after immunotherapy initiation is correlated with poor prognosis in solid cancer patients: An up-to-date systematic review and meta-analysis	40
Efficacy of IVIG (intravenous immunoglobulin) for corona virus disease 2019 (COVID-19): A meta-analysis	40
Interleukin-17 induces pyroptosis in osteoblasts through the NLRP3 inflammasome pathway in vitro	40
Casticin suppresses monoiodoacetic acid-induced knee osteoarthritis through inhibiting HIF-1α/NLRP3 inflammasome signaling	40
Application of extracellular vesicles derived from mesenchymal stem cells as potential therapeutic tools in autoimmune and rheumatic diseases	40
Decursin alleviates the aggravation of osteoarthritis via inhibiting PI3K-Akt and NF-kB signal pathway	39
Up-regulating lncRNA OIP5-AS1 protects neuron injury against cerebral hypoxia-ischemia induced inflammation and oxidative stress in microglia/macrophage through activating CTRP3 via sponging miR-186-5	39
Development and validation of a novel ferroptosis-related gene signature for predicting prognosis and immune microenvironment in head and neck squamous cell carcinoma	39
The Notch signaling pathway regulates macrophage polarization in liver diseases	39
Luteolin activates Tregs to promote IL-10 expression and alleviating caspase-11-dependent pyroptosis in sepsis-induced lung injury	39
Advance in bone destruction participated by JAK/STAT in rheumatoid arthritis and therapeutic effect of JAK/STAT inhibitors	38
PIK3R3 regulates ZO-1 expression through the NF-kB pathway in inflammatory bowel disease	38
SnapShot: TP53 status and macrophages infiltration in TCGA-analyzed tumors	38
Efficacy of baricitinib in treating rheumatoid arthritis: Modulatory effects on fibrotic and inflammatory biomarkers in a real-life setting	38
Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients	38
Mitochondria-derived reactive oxygen species are involved in renal cell ferroptosis during lipopolysaccharide-induced acute kidney injury	38
Acute kidney injury and renal replacement therapy in COVID-19 patients: A systematic review and meta-analysis	38
Glycyrrhetinic acid alleviates hepatic inflammation injury in viral hepatitis disease via a HMGB1-TLR4 signaling pathway	38
Blockade of interleukin-2-inducible T-cell kinase signaling attenuates acute lung injury in mice through adjustment of pulmonary Th17/Treg immune responses and reduction of oxidative stress	38
Intranasal delivery of MSC-derived exosomes attenuates allergic asthma via expanding IL-10 producing lung interstitial macrophages in mice	38
Effectiveness of corticosteroids to treat severe COVID-19: A systematic review and meta-analysis of prospective studies	38
Resveratrol for targeting the tumor microenvironment and its interactions with cancer cells	37
Interleukin-2 therapy of cancer-clinical perspectives	37
Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway	37
Selective Inhibition of NLRP3 Inflammasome Reverses Pressure Overload-Induced Pathological Cardiac Remodeling by Attenuating Hypertrophy, Fibrosis, and Inflammation	37
Clinical characteristics and antibiotics treatment in suspected bacterial infection patients with COVID-19	37
Loganin alleviates sepsis-induced acute lung injury by regulating macrophage polarization and inhibiting NLRP3 inflammasome activation	37
Advanced glycation end products (AGEs) and its receptor, RAGE, modulate age-dependent COVID-19 morbidity and mortality. A review and hypothesis	37
Inhibition of miR-155 alleviates sepsis-induced inflammation and intestinal barrier dysfunction by inactivating NF-κB signaling	37
Tetrahydroxy stilbene glycoside ameliorates Alzheimer’s disease in APP/PS1 mice via glutathione peroxidase related ferroptosis	37
Interleukin-1 in obesity-related low-grade inflammation: From molecular mechanisms to therapeutic strategies	37
miR-193a-5p as a promising therapeutic candidate in colorectal cancer by reducing 5-FU and Oxaliplatin chemoresistance by targeting CXCR4	37
DL0410 attenuates oxidative stress and neuroinflammation via BDNF/TrkB/ERK/CREB and Nrf2/HO-1 activation	37
Curcumin protects against cognitive impairments in a rat model of chronic cerebral hypoperfusion combined with diabetes mellitus by suppressing neuroinflammation, apoptosis, and pyroptosis	36
Colitis following the use of immune checkpoint inhibitors: A real-world analysis of spontaneous reports submitted to the FDA adverse event reporting system	36
Anti-inflammatory effects of natural flavonoid diosmetin in IL-4 and LPS-induced macrophage activation and atopic dermatitis model	36
Emodin attenuates silica-induced lung injury by inhibition of inflammation, apoptosis and epithelial-mesenchymal transition	36
Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-κB, STAT1/3, and Akt signaling pathways	36
Salidroside protects mice against CCl4-induced acute liver injury via down-regulating CYP2E1 expression and inhibiting NLRP3 inflammasome activation	36
Significant immunomodulatory properties of curcumin in patients with osteoarthritis; a successful clinical trial in Iran	36
Mometasone furoate nasal spray in the treatment of patients with COVID-19 olfactory dysfunction: A randomized, double blind clinical trial	36
Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies	36
Intranasal administration of small extracellular vesicles derived from mesenchymal stem cells ameliorated the experimental autoimmune encephalomyelitis	36
Oncostatin M: A mysterious cytokine in cancers	36
The role of Th17 cells in viral infections	36
Baicalin protects LPS-induced blood–brain barrier damage and activates Nrf2-mediated antioxidant stress pathway	36
Mitochondrial DNA in NLRP3 inflammasome activation	36
NLRP3 inflammasome and glia maturation factor coordinately regulate neuroinflammation and neuronal loss in MPTP mouse model of Parkinson’s disease	36

Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2.5-mediated lung injury in mice	35
Polysaccharide of Atractylodes macrocephala Koidz regulates LPS-mediated mouse hepatitis through the TLR4-MyD88-NFκB signaling pathway	35
Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion	35
Nanoparticles of resveratrol attenuates oxidative stress and inflammation after ischemic stroke in rats	35
Coenzyme Q10 attenuates inflammation and fibrosis implicated in radiation enteropathy through suppression of NF-kB/TGF-β/MMP-9 pathways	35
Resveratrol protects intestinal integrity, alleviates intestinal inflammation and oxidative stress by modulating AhR/Nrf2 pathways in weaned piglets challenged with diquat	35
The role of probiotics in coronavirus disease-19 infection in Wuhan: A retrospective study of 311 severe patients	35
Analysis of adjunctive serological detection to nucleic acid test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosis	35
A novel era of cancer/testis antigen in cancer immunotherapy	35
The impact of SGLT2 inhibitors on inflammation: A systematic review and meta-analysis of studies in rodents	35
Activation of PPAR-γ induces macrophage polarization and reduces neutrophil migration mediated by heme oxygenase 1	34
An update review of globally reported SARS-CoV-2 vaccines in preclinical and clinical stages	34
Apatinib enhanced anti-PD-1 therapy for colon cancer in mice via promoting PD-L1 expression	34
6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1 / FAF1 complex dissociation-mediated autophagy	34
Mesenchymal stromal/stem cells and their exosomes application in the treatment of intervertebral disc disease: A promising frontier	34
Hemoglobin, albumin, lymphocyte, and platelet (HALP) score and cancer prognosis: A systematic review and meta-analysis of 13,110 patients	34
Promising effects of tocilizumab in COVID-19: A non-controlled, prospective clinical trial	34
Dexmedetomidine inhibits pyroptosis by down-regulating miR-29b in myocardial ischemia reperfusion injury in rats	34
Safety and efficacy of pembrolizumab plus lenvatinib versus pembrolizumab and lenvatinib monotherapies in cancers: A systematic review	34
Protective effect of isoliquiritigenin on experimental diabetic nephropathy in rats: Impact on Sirt-1/NFκB balance and NLRP3 expression	34
Convalescent plasma may be a possible treatment for COVID-19: A systematic review	34
Inhibiting NLRP3 inflammasome with MCC950 ameliorates perioperative neurocognitive disorders, suppressing neuroinflammation in the hippocampus in aged mice	34
An updated overview of recent advances, challenges, and clinical considerations of IL-6 signaling blockade in severe coronavirus disease 2019 (COVID-19)	34
Evaluation of Encapsulated Eugenol by Chitosan Nanoparticles on the aggressive model of rheumatoid arthritis	33
Evaluation of protein arginine deiminase-4 inhibitor in TNBS- induced colitis in mice	33
Ginsenoside Rd attenuates cerebral ischemia/reperfusion injury by exerting an anti-pyroptotic effect via the miR-139-5p/FoxO1/Keap1/Nrf2 axis	33
Persistence of SARS-CoV-2-specific antibodies in COVID-19 patients	33
Efficacy of the omega-3 fatty acids supplementation on inflammatory biomarkers: An umbrella meta-analysis	33
Liproxstatin-1 alleviates LPS/IL-13-induced bronchial epithelial cell injury and neutrophilic asthma in mice by inhibiting ferroptosis	33
Prevalence of COVID-19 vaccines (Sputnik V, AZD-1222, and Covaxin) side effects among healthcare workers in Birjand city, Iran	33
LncRNA SNHG7 alleviates IL-1β-induced osteoarthritis by inhibiting miR-214-5p-mediated PPARGC1B signaling pathways	33
Oxidative stress and inflammatory markers in patients with COVID-19: Potential role of RAGE, HMGB1, GFAP and COX-2 in disease severity	33
[6]-Gingerol exhibits potent anti-mycobacterial and immunomodulatory activity against tuberculosis	33
SYT16 is a prognostic biomarker and correlated with immune infiltrates in glioma: A study based on TCGA data	33
Understanding the complexities of SARS-CoV2 infection and its immunology: A road to immune-based therapeutics	33
RETRACTED: BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice	33
Exosomal microRNA-98-5p from hypoxic bone marrow mesenchymal stem cells inhibits myocardial ischemia–reperfusion injury by reducing TLR4 and activating the PI3K/Akt signaling pathway	33
Physiological concentrations of bilirubin control inflammatory response by inhibiting NF-κB and inflammasome activation	33
Extracellular vesicles derived from mesenchymal stem cells prevent skin fibrosis in the cGVHD mouse model by suppressing the activation of macrophages and B cells immune response	32
Thymosin α1 therapy in critically ill patients with COVID-19: A multicenter retrospective cohort study	32
Aggravation of autism-like behavior in BTBR T+tf/J mice by environmental pollutant, di-(2-ethylhexyl) phthalate: Role of nuclear factor erythroid 2-related factor 2 and oxidative enzymes in innate imm	32
Hydrogen attenuates radiation-induced intestinal damage by reducing oxidative stress and inflammatory response	32
Imperatorin suppresses IL-1β-induced iNOS expression via inhibiting ERK-MAPK/AP1 signaling in primary human OA chondrocytes	32
The role of IL-17 and anti-IL-17 agents in the immunopathogenesis and management of autoimmune and inflammatory diseases	32
Biological effects of IL-15 on immune cells and its potential for the treatment of cancer	32
Sarcopenia affects clinical efficacy of immune checkpoint inhibitors in non-small cell lung cancer patients: A systematic review and meta-analysis	32
Resolvin D1 mitigates non-alcoholic steatohepatitis by suppressing the TLR4-MyD88‐mediated NF‐κB and MAPK pathways and activating the Nrf2 pathway in mice	31
Neferine alleviates memory and cognitive dysfunction in diabetic mice through modulation of the NLRP3 inflammasome pathway and alleviation of endoplasmic-reticulum stress	31
Identification of immune-related lncRNAs in periodontitis reveals regulation network of gene-lncRNA-pathway-immunocyte	31
Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophages through AMPK/ HIF-1α pathway	31
MicroRNA-155 and antiviral immune responses	31
Role of immune checkpoint inhibitors in the revolutionization of advanced melanoma care	31
E484K and N501Y SARS-CoV 2 spike mutants Increase ACE2 recognition but reduce affinity for neutralizing antibody	31
Chemokine CXCL14; a double-edged sword in cancer development	31
Juglone regulates gut microbiota and Th17/Treg balance in DSS-induced ulcerative colitis	31
Therapeutic vaccines for colorectal cancer: The progress and future prospect	31
Crocetin attenuates the oxidative stress, inflammation and apoptosis in arsenic trioxide-induced nephrotoxic rats: Implication of PI3K/AKT pathway	31
Quercetin amelioratesAspergillus fumigatuskeratitis by inhibiting fungal growth, toll-like receptors and inflammatory cytokines	31
Patients with systemic lupus erythematosus face a high risk of cardiovascular disease: A systematic review and Meta-analysis	31
Tetrahydropalmatine attenuates MSU crystal-induced gouty arthritis by inhibiting ROS-mediated NLRP3 inflammasome activation	31
Shikonin ameliorates D-galactose-induced oxidative stress and cognitive impairment in mice via the MAPK and nuclear factor-κB signaling pathway	31
Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis	31
A network pharmacology-based strategy for predicting anti-inflammatory targets of ephedra in treating asthma	30
Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatments	30
Inhibitory Effect of Quercetin on Propionibacterium acnes-induced Skin Inflammation	30
Rituximab exhibits a better safety profile when used as a first line of treatment for pemphigus vulgaris: A retrospective study	30
ManNAc protects against podocyte pyroptosis via inhibiting mitochondrial damage and ROS/NLRP3 signaling pathway in diabetic kidney injury model	30
Nanomedicine for improvement of dendritic cell-based cancer immunotherapy	30
Exosomes secreted by M2 macrophages promote cancer stemness of hepatocellular carcinoma via the miR-27a-3p/TXNIP pathways	30
An approach towards development of monoclonal IgY antibodies against SARS CoV-2 spike protein (S) using phage display method: A review	30
Safety and efficacy of Rituximab in systemic sclerosis: A systematic review and meta-analysis	30
Role of glucose metabolism in aggressive phenotype of fibroblast-like synoviocytes: Latest evidence and therapeutic approaches in rheumatoid arthritis	30
Empagliflozin, a sodium glucose cotransporter-2 inhibitor, ameliorates peritoneal fibrosis via suppressing TGF-β/Smad signaling	30
Therapeutic potential of bicyclol in liver diseases: Lessons from a synthetic drug based on herbal derivative in traditional Chinese medicine	30
Trophoblast-derived IL-6 serves as an important factor for normal pregnancy by activating Stat3-mediated M2 macrophages polarization	30
Melatonin suppresses ferroptosis via activation of the Nrf2/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury	30
Astilbin protects against cerebral ischaemia/reperfusion injury by inhibiting cellular apoptosis and ROS-NLRP3 inflammasome axis activation	30
NLRP3 inflammasome inhibitor INF39 attenuated NLRP3 assembly in macrophages	30
The immune response and immune evasion characteristics in SARS-CoV, MERS-CoV, and SARS-CoV-2: Vaccine design strategies	30
Inactivated SARS-CoV-2 vaccines elicit immunogenicity and T-cell responses in people living with HIV	30
Modifications of gut microbiota are associated with the severity of IgA nephropathy in the Chinese population	30
Continuous tracking of COVID-19 patients' immune status	30
Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-κB and HO-1 signaling pathways in mice	29
Favipiravir in the treatment of patients with SARS-CoV-2 RNA recurrent positive after discharge: A multicenter, open-label, randomized trial	29
The effectiveness of blood routine parameters and some biomarkers as a potential diagnostic tool in the diagnosis and prognosis of Covid-19 disease	29
Celastrol attenuates collagen-induced arthritis via inhibiting oxidative stress in rats	29
SIRT1 alleviates IL-1β induced nucleus pulposus cells pyroptosis via mitophagy in intervertebral disc degeneration	29
Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway	29
Construction of an immune-related gene signature for prediction of prognosis in patients with cervical cancer	29
Anti-inflammatory effects of Platycodin D on dextran sulfate sodium (DSS) induced colitis and E. coli Lipopolysaccharide (LPS) induced inflammation	29
Dehydrocostus lactone inhibits BLM-induced pulmonary fibrosis and inflammation in mice via the JNK and p38 MAPK-mediated NF-κB signaling pathways	29
Bruton’s tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice	29
Targeting the PD-1/PD-L1 pathway in glioblastoma multiforme: Preclinical evidence and clinical interventions	29
Baicalin protects against zearalenone-induced chicks liver and kidney injury by inhibiting expression of oxidative stress, inflammatory cytokines and caspase signaling pathway	29
Interferon-inducer antivirals: Potential candidates to combat COVID-19	29