Mitochondrion

Papers
(The median citation count of Mitochondrion is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
The role of mtDNA haplogroups on metabolic features in narcolepsy type 1144
The multifaceted modulation of mitochondrial metabolism in tumorigenesis126
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond65
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics63
Hsp90 and its mitochondrial homologue TRAP-1 independently regulate hypoxia adaptations in Caenorhabditis elegans60
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy53
Editorial Board49
Mitofusin 2: The missing link between mtDNA maintenance defects and neurotransmitter disorders40
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis38
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?38
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat37
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma36
Mitochondrial density in skeletal and cardiac muscle34
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect34
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies34
Editorial Board32
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Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive31
The war against Alzheimer, the mitochondrion strikes back!28
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability27
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation26
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos25
Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy25
Mitochondria in biology and medicine – 202324
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation24
Mitophagy in depression: Pathophysiology and treatment targets23
Editorial Board22
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria21
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology21
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells21
Muscle-UCP3 in the regulation of energy metabolism21
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis21
Identification of a novel m.3955G > A variant in MT-ND1 associated with Leigh syndrome21
Blood cell respiration rates and mtDNA copy number: A promising tool for the diagnosis of mitochondrial disease20
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity20
COVID-19 induced liver injury from a new perspective: Mitochondria20
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research20
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism20
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging20
Site-specific mitochondrial dysfunction in neurodegeneration20
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease20
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism19
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis19
The maternal genetic history of tribal populations of Chhattisgarh, India18
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system18
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application17
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis16
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies16
Advancing mitochondria as a therapeutic agent16
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration16
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells15
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease15
Mitochondrial quality control in exercise-mitigated muscular atrophy14
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics14
Corrigendum to “Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA” [Mitochondrion 58 (2021) 303–310]14
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications14
The biology of mitochondrial carrier homolog 214
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption14
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica14
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction14
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis14
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease13
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells13
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia13
Fighting Parkinson’s disease: The return of the mitochondria13
Mitochondrial bioenergetics of breast cancer13
Research progress on paternal mitochondrial inheritance: An overview13
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism13
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability12
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults12
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway12
Visualization of mitophagy using LysoKK, a 7-nitro-2,1,3-benzoxadiazole-(arylpropyl)benzylamine derivative12
Editorial Board12
Targeting the mitochondria in chronic respiratory diseases12
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)12
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations12
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance11
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes11
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines11
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury11
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications11
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice11
Aromatic hydrocarbon receptors in mitochondrial biogenesis and function11
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function11
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S11
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention11
Early cardiac mechanics abnormalities in patients with mitochondrial diseases10
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells10
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes10
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury10
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies10
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme10
Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review10
The constraints of allotopic expression10
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva10
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life9
Associations of mitochondrial genomic variation with successful neurological aging9
Temporal changes and control variables of growth differentiation factor 15 levels during the first week of life in hospitalised newborn infants9
Diagnosis of primary mitochondrial disorders -Emphasis on myopathological aspects9
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation9
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer’s disease9
Deciphering the role of MitomiRs in cancer: A comprehensive review9
Mitochondrial tRNA variants in 811 Chinese probands with Leber’s hereditary optic neuropathy9
Mitochondrial and metabolic features of salugenesis and the healing cycle9
Development of Leigh syndrome with a high probability of cardiac manifestations in infantile-onset patients with m.14453G > A9
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells9
Mitochondrial mechanisms in Treg cell regulation: Implications for immunotherapy and disease treatment9
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation9
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin9
Mitochondrial dynamics and mitochondrial autophagy: Molecular structure, orchestrating mechanism and related disorders9
Mitochondria in aging and age-associated diseases9
The maternal genetic origin and diversity of the extant populations of the Ladakh region in India8
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence8
Role of Rmd9p in 3′-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae8
GenEye24: Novel rapid screening test for the top-3 Leber’s Hereditary Optic Neuropathy pathogenic sequence variants8
Global view of dynamic expression and precise mapping of mitochondrial tRNAs-derived fragments during stressed conditions in S. pombe8
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health8
Altered insulin pathway compromises mitochondrial function and quality control both in in vitro and in vivo model systems8
Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury8
Mitochondrial bioenergetics and cytometric characterization of a synaptosomal preparation from mouse brain cortex8
Mitochondria determine response to anti-programmed cell death protein-1 (anti-PD-1) immunotherapy: An evidence-based hypothesis8
Assessment of mitochondrial DNA copy number variation relative to nuclear DNA quantity between different tissues7
Understanding the molecular basis of anti-fibrotic potential of intranasal curcumin and its association with mitochondrial homeostasis in silica-exposed mice7
Telomere length determines the mitochondrial copy number in blastocyst-stage embryos7
Actin-related protein 4: An unconventional negative regulator of mitochondrial calcium in protozoan parasite Leishmania7
Role of mitochondrial potassium channels in ageing7
Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications7
Clinical and genetic spectrum of mitochondrial DNA depletion syndromes: A report of 6 cases with 4 novel variants7
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank7
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma7
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches7
Corrigendum to “Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1” [Mitochondrion 51 (2019) 15–21]7
Presence and transmission of mitochondrial heteroplasmic mutations in human populations of European and African ancestry7
Editorial Board7
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Image-based quantification of mitochondrial iron uptake via Mitoferrin-26
Interactions between nuclear and mitochondrial SNPs and Parkinson’s disease risk6
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome6
Large-scale screens identify a 19-Gene MitoScore for improved risk assessment in acute myeloid leukemia6
ER stress-associated transcription factor CREB3 is essential for normal Ca2+, ATP, and ROS homeostasis6
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells6
Regulation of mitochondrial network homeostasis by O-GlcNAcylation6
Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions6
Erodible thermogelling hydrogels for localized mitochondrial transplantation to the spinal cord6
Beneficial effects of mitophagy enhancers on amyloid beta-induced mitochondrial and synaptic toxicities in Alzheimer’s disease6
Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children6
mitoPADdb: A database of mitochondrial proteins associated with diseases6
Blood biomarkers for assessment of mitochondrial dysfunction: An expert review6
Energy Metabolism Focused Analysis of Sexual Dimorphism in Biological Aging and Hypothesized Sex-specificity in Sirtuin Dependency6
In vitro models of insulin resistance: Mitochondrial coupling is differently affected in liver and muscle cells6
Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV6
Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration6
Different platforms for mitomiRs in mitochondria: Emerging facets in regulation of mitochondrial functions6
A novel, conserved and possibly functional motif “WHWGHTW” in mitochondrial transcription across Bilateria5
Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury5
ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial respiration5
Revolutionizing cellular energy: The convergence of mitochondrial dynamics and delivery technologies5
Plant mitochondria import DNA via alternative membrane complexes involving various VDAC isoforms5
AutomAted RepeaT Identifier (AARTI): A tool to identify common, polymorphic, and unique microsatellites5
Positive regulation of endothelial Tom70 by metformin as a new mechanism against cardiac microvascular injury in diabetes5
Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes5
Ancient mitogenomes suggest complex maternal history of one of the oldest settlements of western India5
Cyt b gene as a valid molecular authentication marker of cow leathers5
The Schizosaccharomyces pombe DEAD-box protein Mss116 is required for mitoribosome assembly and mitochondrial translation5
The m.3890G>A/MT-ND1 mtDNA rare pathogenic variant: Expanding clinical and MRI phenotypes5
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities5
Neuroprotective effect of autologous mitochondrial transplantation against global ischemia/reperfusion injury in a rat model of cardiac arrest5
Editorial Board5
Simulated microgravity triggers DNA damage and mitochondria-mediated apoptosis through ROS generation in human promyelocytic leukemic cells5
Complete mitochondrial DNA profile in stroke: A geographical matched case-control study in Spanish population4
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer’s disease4
Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I4
Mitochondrial iron-sulfur cluster biogenesis and neurological disorders4
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation4
Krebs cycle derivatives, dimethyl fumarate and itaconate, control metabolic reprogramming in inflammatory human microglia cell line4
A comprehensive perspective of Huntington’s disease and mitochondrial dysfunction4
SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies4
Mitochondrial DNA haplogroup, genetic ancestry, and susceptibility to Ewing sarcoma4
Transplanting mitochondria from gastric epithelial cells reduces the malignancy of gastric cancer4
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications4
Corrigendum to “Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement o4
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells4
Editorial Board4
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