Mitochondrion

Article	Citations
The role of mtDNA haplogroups on metabolic features in narcolepsy type 1	140
Hsp90 and its mitochondrial homologue TRAP-1 independently regulate hypoxia adaptations in Caenorhabditis elegans	130
Mitochondrial calcium signaling in the brain and its modulation by neurotropic viruses	103
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	59
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	58
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	51
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	51
Editorial Board	50
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	46
Mitofusin 2: The missing link between mtDNA maintenance defects and neurotransmitter disorders	46
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	45
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	39
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	37
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	36
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	34
Mitochondrial density in skeletal and cardiac muscle	34
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	33
Editorial Board	32
Editorial Board	32
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	31
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation	30
Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy	30
The war against Alzheimer, the mitochondrion strikes back!	30
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	29
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	28

Mitophagy in depression: Pathophysiology and treatment targets	27
Mitochondria in biology and medicine – 2023	25
Editorial Board	24
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	23
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	23
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	21
Identification of a novel m.3955G > A variant in MT-ND1 associated with Leigh syndrome	21
Muscle-UCP3 in the regulation of energy metabolism	21
Site-specific mitochondrial dysfunction in neurodegeneration	20
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	20
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	20
Circumventing the Crabtree effect in cell culture: A systematic review	19
COVID-19 induced liver injury from a new perspective: Mitochondria	19
Blood cell respiration rates and mtDNA copy number: A promising tool for the diagnosis of mitochondrial disease	19
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	19
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research	19
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	18
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism	18
The maternal genetic history of tribal populations of Chhattisgarh, India	17
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	17
Advancing mitochondria as a therapeutic agent	17
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	17
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	17
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	17
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	16
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	16
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	16
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	16
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	16
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	15
Corrigendum to “Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA” [Mitochondrion 58 (2021) 303–310]	15
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	15
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	15
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	15
Metabolic abnormality in acute stroke-like lesion and its relationship with focal cerebral blood flow in patients with MELAS: Evidence from proton MR spectroscopy and arterial spin labeling	15
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	15
Stressed mitochondria: A target to intrude alzheimer’s disease	15
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	15
The biology of mitochondrial carrier homolog 2	15
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	15
RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	14
Mitochondrial N-methyl-d-aspartate receptor activation enhances bioenergetics by calcium-dependent and –Independent mechanisms	14
Mitochondrial bioenergetics of breast cancer	14
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	14
Polysulfide inhibits hypoxia-elicited hypoxia-inducible factor activation in a mitochondria-dependent manner	14
Research progress on paternal mitochondrial inheritance: An overview	13
Visualization of mitophagy using LysoKK, a 7-nitro-2,1,3-benzoxadiazole-(arylpropyl)benzylamine derivative	13
Fighting Parkinson’s disease: The return of the mitochondria	13
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)	13
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	13

Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	12
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	12
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	12
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	12
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance	12
Targeting the mitochondria in chronic respiratory diseases	12
Editorial Board	12
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	11
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	11
Crystallographic modeling of the PNPT1:c.1453A>G variant as a cause of mitochondrial dysfunction and autosomal recessive deafness; expanding the neuroimaging and clinical features	11
Analysis of compound heterozygous and homozygous mutations found in peripheral subunits of human respiratory Complex I, NDUFS1, NDUFS2, NDUFS8 and NDUFV1, by modeling in the E. coli enzyme	11
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	11
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	11
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	11
Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement of mitochondrial	11
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice	11
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	11
Aromatic hydrocarbon receptors in mitochondrial biogenesis and function	11
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	11
Mitochondria in aging and age-associated diseases	10
Intermittent hypoxia preconditioning protects WRL68 cells against oxidative injury: Involvement of the PINK1/Parkin-mediated mitophagy regulated by nuclear respiratory factor 1	10
Identifying the mitochondrial metabolism network by integration of machine learning and explainable artificial intelligence in skeletal muscle in type 2 diabetes	10
DDQ anti-aging properties expressed with improved mitophagy in mutant tau HT22 neuronal cells	10
MitoQuicLy: A high-throughput method for quantifying cell-free DNA from human plasma, serum, and saliva	10
Early cardiac mechanics abnormalities in patients with mitochondrial diseases	10
Machine learning-based 3D segmentation of mitochondria in polarized epithelial cells	10
The constraints of allotopic expression	10
Transplantation of astrocyte-derived mitochondria into injured astrocytes has a protective effect following stretch injury	10
Associations of mitochondrial genomic variation with successful neurological aging	9
Recent trends of natural based therapeutics for mitochondria targeting in Alzheimer’s disease	9
Mitochondrial mechanisms in Treg cell regulation: Implications for immunotherapy and disease treatment	9
PKD regulates mitophagy to prevent oxidative stress and mitochondrial dysfunction during mouse oocyte maturation	9
HIV-1 gp120 protein promotes HAND through the calcineurin pathway activation	9
The impact of TK2 deficiency syndrome and its treatment by nucleoside therapy on quality of life	9
Sirtuin 3 and mitochondrial permeability transition pore (mPTP): A systematic review	9
Development of Leigh syndrome with a high probability of cardiac manifestations in infantile-onset patients with m.14453G > A	9
Mitochondrial tRNA variants in 811 Chinese probands with Leber’s hereditary optic neuropathy	9
Temporal changes and control variables of growth differentiation factor 15 levels during the first week of life in hospitalised newborn infants	9
Deciphering the role of MitomiRs in cancer: A comprehensive review	8
Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury	8
β-Hydroxybutyrate preferentially enhances neuron over astrocyte respiration while signaling cellular quiescence	8
Role of mitochondrial potassium channels in ageing	8
Mitochondria determine response to anti-programmed cell death protein-1 (anti-PD-1) immunotherapy: An evidence-based hypothesis	8
Global view of dynamic expression and precise mapping of mitochondrial tRNAs-derived fragments during stressed conditions in S. pombe	8
SIRT6 suppresses colon cancer growth by inducing apoptosis and autophagy through transcriptionally down-regulating Survivin	8
The maternal genetic origin and diversity of the extant populations of the Ladakh region in India	8
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health	8
Role of Rmd9p in 3′-end processing of mitochondrial 15S rRNA in Saccharomyces cerevisiae	8
Placental mitochondrial DNA mutational load and perinatal outcomes: Findings from a multi-ethnic pregnancy cohort	8
Clinical heterogeneity in patients with m.4412G > A MT-TM mutation and different heteroplasmy levels	8
Diagnosis of primary mitochondrial disorders -Emphasis on myopathological aspects	8
Mitochondrial dynamics and mitochondrial autophagy: Molecular structure, orchestrating mechanism and related disorders	8
Mitochondrial bioenergetics and cytometric characterization of a synaptosomal preparation from mouse brain cortex	8
GenEye24: Novel rapid screening test for the top-3 Leber’s Hereditary Optic Neuropathy pathogenic sequence variants	8
Mitochondrial Mechanisms in Temozolomide Resistance: Unraveling the Complex Interplay and Therapeutic Strategies in Glioblastoma	8
Mitochondrial and metabolic features of salugenesis and the healing cycle	8
Extracellular vesicles as carriers for mitochondria: Biological functions and clinical applications	7
The mitochondrial chaperone TRAP-1 regulates the glutamine metabolism in tumor cells	7
Large-scale screens identify a 19-Gene MitoScore for improved risk assessment in acute myeloid leukemia	7
Corrigendum to “Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann-Pick C1, Npc1” [Mitochondrion 51 (2019) 15–21]	7
Altered insulin pathway compromises mitochondrial function and quality control both in in vitro and in vivo model systems	7
Understanding the molecular basis of anti-fibrotic potential of intranasal curcumin and its association with mitochondrial homeostasis in silica-exposed mice	7
Editorial Board	7
Clinical and genetic spectrum of mitochondrial DNA depletion syndromes: A report of 6 cases with 4 novel variants	7
Assessment of mitochondrial DNA copy number variation relative to nuclear DNA quantity between different tissues	7
The interplay of epilepsy with impaired mitophagy and autophagy linked dementia (MAD): A review of therapeutic approaches	7
Editorial Board	7
Presence and transmission of mitochondrial heteroplasmic mutations in human populations of European and African ancestry	7
Mitochondrial DNA mutation pathogenicity score and neurocognitive performance in persons with HIV	6
Mitochondrial DNA abundance and circulating metabolomic profiling: Multivariable-adjusted and Mendelian randomization analyses in UK Biobank	6
Interactions between nuclear and mitochondrial SNPs and Parkinson’s disease risk	6
Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions	6
ER stress-associated transcription factor CREB3 is essential for normal Ca2+, ATP, and ROS homeostasis	6
Different platforms for mitomiRs in mitochondria: Emerging facets in regulation of mitochondrial functions	6
The differences in mitochondrial function, mitochondrial dynamics, and cell death between odontogenic cysts/tumors and normal dental follicles	6
Telomere length determines the mitochondrial copy number in blastocyst-stage embryos	6
Mitochondrial dysfunction in diabetic neuropathy: Impaired mitophagy triggers NLRP3 inflammasome	6
In vitro models of insulin resistance: Mitochondrial coupling is differently affected in liver and muscle cells	6
Blood biomarkers for assessment of mitochondrial dysfunction: An expert review	6
Actin-related protein 4: An unconventional negative regulator of mitochondrial calcium in protozoan parasite Leishmania	6

Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children	6
Interplay of mitochondria-associated membrane proteins and autophagy: Implications in neurodegeneration	6
Erodible thermogelling hydrogels for localized mitochondrial transplantation to the spinal cord	6
Positive regulation of endothelial Tom70 by metformin as a new mechanism against cardiac microvascular injury in diabetes	6
Revolutionizing cellular energy: The convergence of mitochondrial dynamics and delivery technologies	5
Image-based quantification of mitochondrial iron uptake via Mitoferrin-2	5
AutomAted RepeaT Identifier (AARTI): A tool to identify common, polymorphic, and unique microsatellites	5
Simulated microgravity triggers DNA damage and mitochondria-mediated apoptosis through ROS generation in human promyelocytic leukemic cells	5
Neuroprotective effect of autologous mitochondrial transplantation against global ischemia/reperfusion injury in a rat model of cardiac arrest	5
Energy Metabolism Focused Analysis of Sexual Dimorphism in Biological Aging and Hypothesized Sex-specificity in Sirtuin Dependency	5
The Schizosaccharomyces pombe DEAD-box protein Mss116 is required for mitoribosome assembly and mitochondrial translation	5
Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes	5
Regulation of mitochondrial network homeostasis by O-GlcNAcylation	5
The m.3890G>A/MT-ND1 mtDNA rare pathogenic variant: Expanding clinical and MRI phenotypes	5
Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury	5
mitoPADdb: A database of mitochondrial proteins associated with diseases	5
A novel, conserved and possibly functional motif “WHWGHTW” in mitochondrial transcription across Bilateria	5
ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial respiration	5
NUDT6 and NUDT9, two mitochondrial members of the NUDIX family, have distinct hydrolysis activities	5
Editorial Board	4
Ancient mitogenomes suggest complex maternal history of one of the oldest settlements of western India	4
Cyt b gene as a valid molecular authentication marker of cow leathers	4
Editorial Board	4
Understanding the neuronal synapse and challenges associated with the mitochondrial dysfunction in mild cognitive impairment and Alzheimer’s disease	4
Transplanting mitochondria from gastric epithelial cells reduces the malignancy of gastric cancer	4
Corrigendum to “Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement o	4
Mitochondrial iron-sulfur cluster biogenesis and neurological disorders	4
Mitochondrial DNA haplogroup, genetic ancestry, and susceptibility to Ewing sarcoma	4
SDHAF2 facilitates mitochondrial respiration through stabilizing succinate dehydrogenase and cytochrome c oxidase assemblies	4
A comprehensive perspective of Huntington’s disease and mitochondrial dysfunction	4
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications	4
A hitchhiker’s guide to mitochondrial quantification	4
Plant mitochondria import DNA via alternative membrane complexes involving various VDAC isoforms	4
Genes from oxidative phosphorylation complexes II-V and two dual-function subunits of complex I are transcribed in Viscum album despite absence of the entire mitochondrial holo-complex I	4
Melatonin protects against excessive autophagy-induced mitochondrial and ovarian reserve function deficiency though ERK signaling pathway in Chinese hamster ovary (CHO) cells	4
MicroRNA-338 inhibition protects against focal cerebral ischemia and preserves mitochondrial function in vitro in astrocytes and neurons via COX4I1	4
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation	3
Leber’s hereditary optic neuropathy: Current approaches and future perspectives on Mesenchymal stem cell-mediated rescue	3
Cell-free mtDNA level and its biomarker potency for ART outcome are different in follicular fluid of PCOS and non-PCOS women	3
Increased expression of SLC25A18 is associated with Alzheimer’s disease and is involved in Aβ42-induced mitochondrial dysfunction and apoptosis in neuronal cells	3
Differential responses of AMD mitochondrial DNA haplogroups to PU-91, a mitochondria-targeting drug	3
Scientific investigation of non-coding RNAs in mitochondrial epigenetic and aging disorders: Current nanoengineered approaches for their therapeutic improvement	3
Mitochondrial respiration is controlled by Allostery, Subunit Composition and Phosphorylation Sites of Cytochrome c Oxidase: A trailblazer’s tale – Bernhard Kadenbach	3
Long read mitochondrial genome sequencing using Cas9-guided adaptor ligation	3
Complete mitochondrial DNA profile in stroke: A geographical matched case-control study in Spanish population	3
Mitochondrial functioning in Rheumatoid arthritis modulated by estrogen: Evidence-based insight into the sex-based influence on mitochondria and disease	3
Dysregulation of mitochondrial complexes and dynamics by chronic cigarette smoke exposure Utilizing MitoQC reporter mice	3
WITHDRAWN: Advances in mitochondrial medicine and translational research	3
Cell-penetrating peptides with nanoparticles hybrid delivery vectors and their uptake pathways	3
Editorial Board	3
Phenotypes and genotypes of mitochondrial diseases with mtDNA variations in Chinese children: A multi-center study	3
Mitochondrial transfer from mesenchymal stem cells: Mechanisms and functions	3
Krebs cycle derivatives, dimethyl fumarate and itaconate, control metabolic reprogramming in inflammatory human microglia cell line	3
Mitochondrial dysfunction, a weakest link of network of aging, relation to innate intramitochondrial immunity of DNA recognition receptors	3
Corrigendum to “Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism” [Mitochondrion 71 (2023) 40-49]	3
Precise annotation of Drosophila mitochondrial genomes leads to insights into AT-rich regions	3
Augmented Parkin-dependent mitophagy underlies the hepatoprotective effect of remote ischemic conditioning used prior to hemorrhagic shock	3
Molecular docking and simulation studies of phytocompounds derived from Centella asiatica and Andrographis paniculata against hexokinase II as mitocan agents	3