OOIR: Observatory of International Research

Papers

(The TQCC of Mitochondrion is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
The multifaceted modulation of mitochondrial metabolism in tumorigenesis	146
The tissue-specific nature of physiological zebrafish mitochondrial bioenergetics	73
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy	68
Sequencing errors in Native American mitogenomes: Impact on clade definitions, haplogroup assignation, and beyond	60
The role of mtDNA haplogroups on metabolic features in narcolepsy type 1	58
Activation of multifunctional DNA repair APE1/Ref-1 enzyme by the dietary phytochemical Ferulic acid protects human neuroblastoma SH-SY5Y cells against Aβ(25–35)-induced oxidative stress and inflammat	52
Delivery of mitoceuticals or respiratory competent mitochondria to sites of neurotrauma	50
What can we do to optimize mitochondrial transplantation therapy for myocardial ischemia–reperfusion injury?	48
Editorial Board	43
Mitofusin 2: The missing link between mtDNA maintenance defects and neurotransmitter disorders	43
ACAD9 treatment with bezafibrate and nicotinamide riboside temporarily stabilizes cardiomyopathy and lactic acidosis	39
A Tunisian POLG mutation expands the clinical spectrum of POLG-related disorders	39
The role of mitochondrial genes in ischemia-reperfusion injury: A systematic review of experimental studies	38
Thyroid hormone enhances efficacy of cisplatin in lung cancer patients via down-regulating GLUT1 expression and reversing the Warburg effect	37
Editorial Board	36
PKM2 is a key regulator of cardiac lipid metabolism in mice	36
Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive	34
Role of GM-CSF in regulating metabolism and mitochondrial functions critical to macrophage proliferation	33
The war against Alzheimer, the mitochondrion strikes back!	31
Mitochondrial density in skeletal and cardiac muscle	30
Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy	30
Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos	30
Editorial Board	30
PhNR and peripapillary RNFL changes in Leber hereditary optic neuropathy with m.G11778A mutation	28
Mrs2-mediated mitochondrial magnesium uptake is essential for the regulation of MCU-mediated mitochondrial Ca2+ uptake and viability	28

Mitophagy in depression: Pathophysiology and treatment targets	26
Mitochondria in biology and medicine – 2023	26
Pyridoxal-5-phosphate mitigates age-related metabolic imbalances in the rat heart through the H2S/AKT/GSK3β signaling axis	26
Reactive oxygen species favors Varicellovirus bovinealpha 5 (BoAHV-5) replication in neural cells	25
Muscle-UCP3 in the regulation of energy metabolism	25
Mitochondrial genome-derived circRNAs: Orphan epigenetic regulators in molecular biology	24
Genomic and non-genomic action of vitamin D on ion channels – Targeting mitochondria	24
Editorial Board	23
Site-specific mitochondrial dysfunction in neurodegeneration	23
Identification of a novel m.3955G > A variant in MT-ND1 associated with Leigh syndrome	22
TRPV4 acts as a mitochondrial Ca2+-importer and regulates mitochondrial temperature and metabolism	22
Decoding the nature and complexity of extracellular mtDNA: Types and implications for health and disease	22
COVID-19 induced liver injury from a new perspective: Mitochondria	21
Reviewing the mitochondrial dysfunction paradigm in rodent models as platforms for neuropsychiatric disease research	21
Blood cell respiration rates and mtDNA copy number: A promising tool for the diagnosis of mitochondrial disease	21
Mitochondrial Irc3 helicase of the thermotolerant yeast Ogataea polymorpha displays dual DNA- and RNA-stimulated ATPase activity	20
Impact of missense mutations on the structure–function relationship of human succinyl-CoA synthetase using in silico analysis	19
Exploring the role of mitochondria transfer/transplant and their long-non-coding RNAs in regenerative therapies for skin aging	19
Mitochondrial transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism	19
The maternal genetic history of tribal populations of Chhattisgarh, India	18
Association analysis of mitochondrial DNA heteroplasmic variants: Methods and application	18
Understanding differential aspects of microdiffusion (channeling) in the Coenzyme Q and Cytochrome c regions of the mitochondrial respiratory system	17
Urolithin-A supplementation alleviates sepsis-induced acute lung injury by reducing mitochondrial dysfunction and modulating macrophage polarization	17
Targeted mitochondrial metabolism for anti-tumor therapy	17
Mitochondrial oxidative stress in brain microvascular endothelial cells: Triggering blood-brain barrier disruption	17
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration	17
2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson’s disease	16
Mitochondria dysfunction and impaired response to oxidative stress promotes proteostasis disruption in aged human cells	16
Advancing mitochondria as a therapeutic agent	16
Serum TCA cycle metabolites in Lewy bodies dementia and Alzheimer's disease: Network analysis and cognitive prognosis	16
Interplay of mitochondria and diabetes: Unveiling novel therapeutic strategies	16
Mitochondrial quality control in exercise-mitigated muscular atrophy	15
Kinetic characterization of respirasomes and free complex I from Yarrowia lipolytica	15
Mitochondrial dysfunction and inflammasome activation in neurodegenerative diseases: Mechanisms and therapeutic implications	15
An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis	15
Corrigendum to “Comparison of whole genome sequencing and targeted sequencing for mitochondrial DNA” [Mitochondrion 58 (2021) 303–310]	15
Mitochondrial bioenergetics of breast cancer	14
Novel mutations in MTERF3: First report of a new genetic cause in two Chinese patients with developmental delay, intermittent hypoglycemia and metabolic acidosis	14
Application research of novel peptide mitochondrial-targeted antioxidant SS-31 in mitigating mitochondrial dysfunction	14
Neuroprotective compounds alter the expression of genes coding for proteins related to mitochondrial function in activated microglia	14
The biology of mitochondrial carrier homolog 2	14
Miro1 improves the exogenous engraftment efficiency and therapeutic potential of mitochondria transfer using Wharton's jelly mesenchymal stem cells	13
Research progress on paternal mitochondrial inheritance: An overview	13
Visualization of mitophagy using LysoKK, a 7-nitro-2,1,3-benzoxadiazole-(arylpropyl)benzylamine derivative	13
Fighting Parkinson’s disease: The return of the mitochondria	13
Targeting the mitochondria in chronic respiratory diseases	13
Targeting mitochondria with small molecules: A promising strategy for combating Parkinson’s disease	13
Whole genome sequencing followed by functional analysis of genomic deletion encompassing ERCC8 and NDUFAF2 genes in a non-consanguineous Indian family reveals dysfunctional mitochondrial bioenergetics	13
The Parkinson’s disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway	13
Prognostic value of circulating mitochondrial DNA in prostate cancer and underlying mechanism	13

RTN3 deficiency exacerbates cisplatin-induced acute kidney injury through the disruption of mitochondrial stability	13
Selective and reversible disruption of mitochondrial inner membrane protein complexes by lipophilic cations	13
Defining ER-mitochondria contact dynamics in Plasmodium falciparum by targeting component of phospholipid synthesis pathway, phosphatidylserine synthase (PfPSS)	13
Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications	12
Editorial Board	12
Aromatic hydrocarbon receptors in mitochondrial biogenesis and function	12
Ancestry affects the transcription of small mitochondrial RNAs in human lymphocytes	12
Altered brown adipose tissue mitochondrial function in newborn fragile X syndrome mice	12
Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance	12
Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S	12
Role of mitophagy in pulmonary hypertension: Targeting the mechanism and pharmacological intervention	12
Receptor-mediated mitophagy: An emerging therapeutic target in acute kidney injury	12
WITHDRAWN: Mitochondrial oxygen respiration is associated with loneliness in a sample of community-dwelling adults	11
Perceived association of mood and symptom severity in adults with mitochondrial diseases	11
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies	11
Differentiation activates mitochondrial OPA1 processing in myoblast cell lines	11
Type 1 diabetes mellitus: Inflammation, mitophagy, and mitochondrial function	11
Editorial Board	11