Current Cancer Drug Targets

Article	Citations
The Expression of Glutaminases and their Association with Clinicopathological Parameters in the Head and Neck Cancers	75
Expression, Prognostic Value, and Immune Infiltration of MTHFD Family in Bladder Cancer	39
Combined RNAi of CTTN and FGF2 Modulates Cell Migration, Invasion and G1/S Transition of Hepatocellular Carcinoma through Ras/ERK Signaling Pathway	38
Identification of ATM Mutation as a Potential Prognostic Biomarker for Immune Checkpoint Inhibitors Therapy	27
A Review on Patient-derived 3D Micro Cancer Approach for Drug Screen in Personalized Cancer Medicine	25
The Clinical Application of Circulating Tumor Cells and DNAs as Prognostic and Predictive Biomarkers in Gastrointestinal Cancer	24
Efficacy and Safety of Immunotherapy Combined with Anlotinib as FirstLine Treatment in Older NSCLC Patients with PD-L1 Expression<50%	24
Spinal KCC2 Mediates the Modulation Effect of HDAC2 on Bone Cancer Pain in Rats	24
Micro-fragmented Fat Inhibits the Progression of Human Mesothelioma Xenografts in Mice	22
Unveiling Novel Therapeutic Drug Targets and Prognostic Markers of Triple Negative Breast Cancer	21
A Pilot Study of Anlotinib as a Combination Treatment in Advanced Nasopharyngeal Carcinoma	21
Development of Chromatin Regulator-related Molecular Subtypes and a Signature to Predict Prognosis and Immunotherapeutic Response in Head and Neck Squamous Cell Carcinoma	19
Crosstalk of Long Non-coding RNAs and EMT: Searching the Missing Pieces of an Incomplete Puzzle for Lung Cancer Therapy	18
Silencing HEATR1 Rescues Cisplatin Resistance of Non-small Cell Lung Cancer by Inducing Ferroptosis via the p53/SAT1/ALOX15 Axis	15
Knockdown of PRKD2 Enhances Chemotherapy Sensitivity in Cervical Cancer via the TP53/CDKN1A Pathway	15
Immune Checkpoint Inhibitors for Advanced Biliary Tract Cancer	14
Bioinformatics and Experimental Study Revealed LINC00982/ miR-183-5p/ABCA8 Axis Suppresses LUAD Progression	14
TBOPP, a DOCK1 Inhibitor, Potentiates Cisplatin Efficacy in Breast Cancer by Regulating Twist-mediated EMT	13
FHOD3 Promotes the Progression of Lung Cancer by Regulating the Caspase-3-Mediated Signaling Pathway	13
Progress in Metabolic Studies of Gastric Cancer and Therapeutic Implications	12
Etiology-based Molecular Characterization of Hepatocellular Carcinoma Reveals SQLE’s Contribution to Immunosuppressive Microenvironment	12
The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention	12
LMNB1/CDKN1A Signaling Regulates the Cell Cycle and Promotes Hepatocellular Carcinoma Progression	12
LINC00461 Knockdown Enhances the Effect of Ixazomib in Multiple Myeloma Cells	11
MMP7, Regulated by c-Jun, is Involved in Oral Squamous Cell Carcinoma and Associated with Cancer-Related Fibroblasts Infiltration	11

Interrupted Crosstalk between Natural Killer Cells and Anti-epidermal Growth Factor Receptor: A Possible Role in Hepatocellular Carcinoma Treatment Failure	11
Inorganic Phosphate (Pi) in the Breast Cancer Microenvironment: Production, Transport and Signal Transduction as Potential Targets for Anticancer Strategies	11
PLCG2, A Regulator of Lung Adenocarcinoma Proliferation and Migration Associated with Immune Infiltration	11
Role of Natural Nuclear Factor Erythroid-2-related Factor 2 (Nrf2) Activators in Oral and Head and Neck Cancer Treatment	11
Downregulation of CCKBR Expression Inhibits the Proliferation of Gastric Cancer Cells, Revealing a Potential Target for Immunotoxin Therapy	11
Review Deciphering the Potential of Nanotherapeutics in Lung Cancer Management	10
Use of Tumor-Infiltrating Lymphocyte (TIL) Cell Therapy For Spindle Cell Carcinoma of the Breast: A Case Report	10
Low Expression of SCN4B Predicts Poor Prognosis in Non-small Cell Lung Cancer	10
A Molecular Link Between Diabetes and Breast Cancer: Therapeutic Potential of Repurposing Incretin-based Therapies for Breast Cancer	10
Targeting the HIF-1α/Cav-1 Pathway with a Chicory Extract/Daidzein Combination Plays a Potential Role in Retarding Hepatocellular Carcinoma	9
Epigallocatechin-3-gallate Induced HepG2 Cells Apoptosis through ROSmediated AKT /JNK and p53 Signaling Pathway	9
EGF/EGFR Promotes Salivary Adenoid Cystic Carcinoma Cell Malignant Neural Invasion via Activation of PI3K/AKT and MEK/ERK Signaling	9
Angiotensin-converting Enzyme Inhibitors and Angiotensin Receptor Blockers as Potential Therapeutic Options for Pancreatic Cancer	9
High Expression of PKMYT1 Predicts Poor Prognosis and Aggravates the Progression of Osteosarcoma via the NF-κB Pathway in MG63 Cells	9
Nanodiamond Mediated Molecular Targeting in Pancreatic Ductal Adenocarcinoma: Disrupting the Tumor-stromal Cross-talk, Next Hope on the Horizon?	9
Preventive and Therapeutic effects of Metformin in Cancer: A Meta-Analysis of RCT and Cohort Studies	8
CEA-regulated Oncolytic Virus Anticancer Therapy: A Promising Strategy for Rare Solid Tumors	8
Protein Tyrosine Phosphatase 1B (PTP1B): Insights into its New Implications in Tumorigenesis	8
Utilization of DNA Replication factor MCM2 by Cancer	8
Withaferin A Inhibits Liver Cancer Tumorigenesis by Suppressing Aerobic Glycolysis through the p53/IDH1/HIF-1α Signaling Axis	8
Solid CaCO3 Formation in Glioblastoma Multiforme and its Treatment with Ultra-Nanoparticulated NPt-Bionanocatalysts	8
Comprehensive Pan-cancer Analysis of CMPK2 as Biomarker and Prognostic Indicator for Immunotherapy	8
Identification of AHSA1 as a Potential Therapeutic Target for Breast Cancer: Bioinformatics Analysis and in vitro Studies	8
Real-world Study on the Effect of PARPi as Maintenance Therapy on Platinum Sensitivity after First- and Second-line Chemotherapy in Patients with Recurrent High-grade Serous Epithelial Ovarian Cancer	8
Screening miRNAs to Hinder the Tumorigenesis of Renal Clear Cell Carcinoma Associated with KDR Expression	7
Transcription Factor MAZ Potentiates the Upregulated NEIL3-mediated Aerobic Glycolysis, thereby Promoting Angiogenesis in Hepatocellular Carcinoma	7
Promotion of Cervical Cancer Cell Proliferation by miR-130b Expression Level Changes and Inhibition of its Apoptosis by Targeting CDKN1A Gene	7
Targeting Glutamine Metabolic Reprogramming in Pancreatic Cancer: Current Insights and Future Directions	7
Precision Medicine in Colorectal Cancer: Targeted Therapies and Biomarker Insights	7
WITHDRAWN: Hidrosmin Attenuates Inflammatory Response Induced by IL1β by Suppressing the Activation of NF-κB Involving Nrf2/HO1 Pathway in Human Osteoarthritis Chondrocytes	7
Anti-breast Cancer Potential of Prosopis cineraria L. Phytocompounds: A Network Pharmacology and in vitro Analysisbased Approach	7
A Saffron-based Polyherbal Formulation DuK Prevents Hepatocellular Carcinoma in Male Wistar Rats	7
Stabilizing Scaffold for Short Peptides Based on Knottins	7
Curcumin Inhibits Vasculogenic Mimicry via Regulating ETS-1 in Renal Cell Carcinoma	7
An Updated Review on Molecular Biomarkers in Diagnosis and Therapy of Colorectal Cancer	7
Twenty-four-month Progression-free Survival in HER2-amplified Advanced Gastric Cancer with Brain Metastases after Trastuzumab Deruxtecan Treatment: A Case Report and Literature Review	7
Cancer Vaccine in Cold Tumors: Clinical Landscape, Challenges, and Opportunities	7
Recent Advancements in Drug Targeting for Ferroptosis as an Antitumor Therapy: Development of Novel therapeutics	7
RON Receptor Tyrosine Kinase in Tumorigenic Stemness as a Therapeutic Target of Antibody-drug Conjugates for Eradication of Triple-negative Breast Cancer Stem Cells	6
CDK8 as a therapeutic target for overall survival prediction in cervical squamous cell carcinoma (CESC)	6
Autophagy in Cancer Cell Transformation: A Potential Novel Therapeutic Strategy	6
Pathological Implications of Mucin Signaling in Metastasis	6
Spleen Glucose Metabolism on [18F]-FDG PET/CT for Cancer Drug Discovery and Development cannot be Overlooked	6
Association of Polymorphism in Survivin Gene and the Risk of Liver Cancer Resulting from Hepatitis C Virus Among Egyptian Patients	6
FA-HA-Amygdalin@Fe2O3 and/or γ-Rays Affecting SIRT1 Regulation of YAP/TAZ-p53 Signaling and Modulates Tumorigenicity of MDA-MB231 or MCF-7 Cancer Cells	6
TROP2 Down-regulated DSG2 to Promote Gastric Cancer Cell Invasion and Migration by EGFR/AKT and DSG2/PG/β-Catenin Pathways	6
Efficacy and Safety of Phosphatidylinositol 3-kinase Inhibitors for Patients with Breast Cancer: A Systematic Review and Meta-analysis of Randomized Controlled Trials	6
Single Nucleotide Polymorphisms as the Efficient Prognostic Markers in Breast Cancer	6
The Long Non-coding RNA Cytoskeleton Regulator (CYTOR) Sponges microRNA- 206 (miR-206) to Promote Proliferation and Invasion of HP75 Cells	6
Gender Matters. Sex-related Differences in Immunotherapy Outcome in Patients with Non-small Cell Lung Cancer	6

Silencing TRIM29 Sensitizes Non-small Cell Lung Cancer Cells to Anlotinib by Promoting Apoptosis via Binding RAD50	6
HIF-1α/Malat1/miR-141 Axis Activates Autophagy to Increase Proliferation, Migration, and Invasion in Triple-negative Breast Cancer	6
Advances and Future Prospects of Lipid-Based Nanocarriers in Targeted Cancer Therapy: A Comprehensive Review	6
Elucidation of the Role of the Epigenetic Regulatory Mechanisms of PI3K/Akt/mTOR Signaling Pathway in Human Malignancies	6
Progressive Dynamics of Cancer Stem Cells in Oral Squamous Cell Carcinoma	6
Neuronatin Promotes the Progression of Non-small Cell Lung Cancer by Activating the NF-κB Signaling	6
Long Non-Coding RNA HCP5 Affects Ferroptosis in Lung Adenocarcinoma through miR-17-5p/HOXA7 Axis	6
A Novel Platinum-Resistance-related Gene Signature in Ovarian Cancer: Identification and Patient-derived Organoids Verification	5
Exploring the Role of Long Non-Coding RNAs in Mediating Cisplatin Resistance in Colorectal Cancer	5
Silencing of FANCI Promotes DNA Damage and Sensitizes Ovarian Cancer Cells to Carboplatin	5
mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA	5
Cuproptosis Related Gene DLD Associated with Poor Prognosis and Malignant Biological Characteristics in Lung Adenocarcinoma	5
L-lysine Increases the Anticancer Effect of Doxorubicin in Breast Cancer by Inducing ROS-dependent Autophagy	5
Combination Therapy with Androgen Receptor Pathway Inhibitors for Prostate Cancer	5
COL10A1 as a Prognostic Biomarker in Association with Immune Infiltration in Prostate Cancer	5
WEE Family Kinase Inhibitors Combined with Sorafenib Can Selectively Inhibit HCC Cell Proliferation	5
Exosome-mediated Induction of Apoptosis in Cisplatin-treated Gastric Cancer Cells as a Strategy to Mitigate Side Effects	5
Exploring the Impact of Chitosan-Based Nanoparticles in Cancer Targeted Drug Delivery: A Bibliometric Review	5
ADH1B Gene Promotes Gastric Cancer Tumorigenesis and its Cisplatin Resistance through the EMT Pathway	5
A Novel Oncogenic Role of Disulfidptosis-related Gene SLC7A11 in Anti-tumor Immunotherapy Response to Human Cancers	5
Repurposing of Antidiarrheal Loperamide for Treating Melanoma by Inducing Cell Apoptosis and Cell Metastasis Suppression In vitro and In vivo	5
Assessing Long Non-coding RNAs in Tobacco-associated Oral Cancer	5
Chimeric Antigen Receptor (CAR) T-cell Therapy: A New Genetically Engineered Method of Immunotherapy for Cancer	5
The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma	5
Current Challenges in Targeting Tumor Desmoplasia to Improve the Efficacy of Immunotherapy	5
Coriandrum sativum and Aloysia triphylla can Protect the Development of Cancer: An in Vivo Study using Mouse Painting Assay	5
Tumor-Activated Neutrophils Promote Lung Cancer Progression through the IL-8/PD-L1 Pathway	5
ZIP14 Affects the Proliferation, Apoptosis, and Migration of Cervical Cancer Cells by Regulating the P38 MAPK Pathway	5
Comparison of Surgical and Colonoscopy Tissue to Establish Colorectal Patient-derived Organoids	5
Combinatorial Application of Papain and CD66B for Isolating Glioma- Associated Neutrophils	5
Dietary Flavonoids with Catechol Moiety Inhibit Anticancer Action of Bortezomib: What about the other Boronic Acid-based Drugs?	4
Antibody-drug Conjugate Targets, Drugs, and Linkers	4
Research Advances of Clinical Application of Oncolytic Viruses in Treatment of Gynecologic Cancers	4
Molecular Targets and Nano-Technological Approaches in the Treatment of Hepatic Carcinoma	4
Sildenafil Inhibits the Growth and Epithelial-to-mesenchymal Transition of Cervical Cancer via the TGF-β1/Smad2/3 Pathway	4
Mitochondrial Calcium Uniporter (MCU) that Modulates Mitochondrial Calcium Uptake and Facilitates Endometrial Cancer Progression through Interaction with VDAC1	4
Efficacy and Safety of Nimotuzumab in Combination with Radiotherapy or Chemoradiotherapy for Local Advanced Head and Neck Cancer: A Systematic Review and Meta-analysis	4
Preface	4
AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling Pathway	4
Research Progress of Neural Invasion in Pancreatic Cancer	4
The Effects of Mesenchymal Stem Cells Loaded with Oncolytic Coxsackievirus A21 on Mouse Models of Colorectal Cancer	4
The Clinical Role of Hypoxia Inducible Factor (HIF) Inhibition in Renal Cancer: A Focus on Belzutifan	4
UCA1 Inhibits NKG2D-mediated Cytotoxicity of NK Cells to Breast Cancer	4
Forkhead Box Protein M1 (FOXM1): Prospective Prognostic Biomarker and Therapeutic Targets in Oral Cancer	4
IR-780 Dye-based Targeting of Cancer-associated Fibroblasts Improves Cancer Immunotherapy by Increasing Intra-tumoral T Lymphocytes Infiltration	4
Present and Future Prospects of the Anti-cancer Activities of Saikosaponins	4
Preface	4
VX-765 has a Protective Effect on Mice with Ovarian Injury Caused by Chemotherapy	4
Advances in Radiation Therapy Enhancement and Radio-Protection By Nano-Curcumins: A Systematic Review	4
Nanotechnological Advancements for the Theranostic Intervention in Anaplastic Thyroid Cancer: Current Perspectives and Future Direction	4
RAD50 Deficient in a Breast Cancer Model Predicts Sensitivity to PARP Inhibitors	4
Resistance of Lenvatinib in Hepatocellular Carcinoma	4
Angiogenesis and Pancreatic Cancer: Novel Approaches to Overcome Treatment Resistance	4
Polyphyllin VII is a Potential Drug Targeting CD44 Positive Colon Cancer Cells	4
Disulfiram-Copper Potentiates Anticancer Efficacy of Standard Chemo-therapy Drugs in Bladder Cancer Animal Model through ROS-Autophagy-Ferroptosis Signalling Cascade	4
Combined Immunotherapy and Targeted Therapies for Cancer Treatment: Recent Advances and Future Perspectives	4
The Influence of KIR Gene Polymorphisms and KIR-ligand Binding on Outcomes in Hematologic Malignancies following Haploidentical Stem Cell Transplantation: A Comprehensive Review	4
Experimental Determination of Cancer Drug Targets with Independent Mechanisms of Resistance	3
Metastatic Breast Cancer, Organotropism and Therapeutics: A Review	3
GAPVD1 Promotes the Proliferation of Triple-negative Breast Cancer Cells by Regulating the ERK/MAPK Signaling Pathway	3
Recent Progress in the Application of Exosome Analysis in Ovarian Cancer Management	3
Up-regulation of Core 1 Beta 1, 3-Galactosyltransferase Suppresses Osteosarcoma Growth with Induction of IFN-γ Secretion and Proliferation of CD8+ T Cells	3
Perspectives on Ergodic Cancer Therapy Derived from Cloning Genome Chaos via In Vivo Rhabdomyosarcoma RA-2 Models: a Narrative Review	3
Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice	3
H3K27ac-activated LncRNA NUTM2A-AS1 Facilitated the Progression of Colorectal Cancer Cells via MicroRNA-126-5p/FAM3C Axis	3
Gastroenteropancreatic Neuroendocrine Neoplasms (GEP NENs): The Role of Checkpoint Inhibitors	3
Nanotechnology-enabled Chemodynamic Therapy and Immunotherapy	3
Effects of HSV-G47Δ Oncolytic Virus on Telomerase and Telomere Length Alterations in Glioblastoma Multiforme Cancer Stem Cells Under Hypoxia and Normoxia Conditions	3
The Prognostic Value and Clinical Significance of lncRNA SNHG5 Expression in Patients with Multiple Malignancies: A Bioinformatic and Meta-analysis	3
Εmerging Biomarkers in the Diagnosis and Treatment of Testicular Tumors	3
Cross Talk between COVID-19 and Breast Cancer	3
Durable Disease-free Survival in a Patient with Metastatic Triple-negative Breast Cancer Treated with Olaparib Monotherapy	3
Dihydrotanshinone I Inhibits Pancreatic Cancer Progression via Hedgehog/ Gli Signal Pathway	3
Current Perspectives in Ultra-sensitive Detection of Cancer-specific Biomarkers and Therapeutic Targets	3
Study on Cellular Localization of Bin Toxin and its Apoptosis-inducing Effect on Human Nasopharyngeal Carcinoma Cells	3
Clinical Efficacy and Safety of Anlotinib Combined with Immune Checkpoint Inhibitors in the Treatment of Advanced Squamous Cell Lung Cancer: A Retrospective Single-Center Study in China	3
LINC00887 Acts as an Enhancer RNA to Promote Medullary Thyroid Carcinoma Progression by Binding with FOXQ1	3
Dextran Sulfate Inhibits Cell Proliferation and Induces Apoptosis by Regulating EZH2 in Gastric Carcinoma	3
Advancements in Phytosomal Therapies for Liver Cancer: A Comprehensive Review	3
GPX4 Inhibition Enhances the Antitumor Effect of PARP Inhibitor on Homologous Recombination Proficient Ovarian Cancer Cells	3

Modifications of Ribonucleases in Order to Enhance Cytotoxicity in Anticancer Therapy	3
The Role of Local Angiotensin II/Angiotensin Type 1-receptor Mechanisms in Adipose Tissue Dysfunction to Promote Pancreatic Cancer	3
The Association between NADPH Oxidase 2 (NOX2) and Drug Resistance in Cancer	3
Insights into the Emerging Therapeutic Targets of Triple-negative Breast Cancer	3
Traditional Chinese Medicine Targeting Sarcoma Virus Oncogene-related Diseases	3
CT109-SN-38, a Novel Antibody-drug Conjugate with Dual Specificity for CEACAM5 and 6, Elicits Potent Killing of Pancreatic Cancer Cells	3
Embracing the Circular Journey of RNA in Colorectal Cancer	3
The Therapeutic Potential of MAPK/ERK Inhibitors in the Treatment of Colorectal Cancer	3
The Role of Oxidative Stress in the Development and Therapeutic Intervention of Hepatocellular Carcinoma	3
Cholangiocarcinoma Therapeutics: An Update	2
MALAT1 Promotes Tumorigenesis and Increases Cellular Sensitivity to Herceptin in HER2-positive Breast Cancer	2
A Pan-cancer Analysis to Determine the Prognostic Analysis and Immune Infiltration of HSPA5	2
Emerging Prospects for the Study of Colorectal Cancer Stem Cells using Patient-derived Organoids	2
Corrigendum to: Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	2
Recent Update on Nanoparticles Based Approaches for Management of Cancer: Wave from Traditional to Advanced Technology	2
Probiotics as a Therapeutic Approach in Colorectal Cancer	2
Novel Synergistic Combination of Pamidronate and Temozolomide for Breast Cancer Therapeutics	2
DTL is a Novel Downstream Gene of E2F1 that Promotes the Progression of Hepatocellular Carcinoma	2
An Overview of the Dichotomous Role of Microbiota in Cancer Progression and Management	2
SULF1 Activates the VEGFR2/PI3K/AKT Pathway to Promote the Development of Cervical Cancer	2
Targeting Ferroptosis Pathways: A Novel Strategy for Cancer Therapy	2
Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia	2
Dysregulated Epigenetics of Chordoma: Prognostic Markers and Therapeutic Targets	2
Deubiquitylase USP31 Induces Autophagy and Promotes the Progression in Lung Squamous Cell Carcinoma Cells by Stabilizing E2F1 Expression	2
Preparation of Modified Chitosan-based Nanoparticles for Efficient Delivery of Doxorubicin and/or Cisplatin to Breast Cancer Cells	2
WITHDRAWN: Network Pharmacology and In vitro Experiments Reveal that Noscapine Induces Ros-mediated Apoptosis and Cell Cycle Arrest via PI3K/Akt/FoxO3a Signaling Pathway in Human Bladder Cancer Cells	2
Biology, Significance and Immune Signaling of Mucin 1 in Hepatocellular Carcinoma	2
CDK-associated Cullin 1 Promotes Cell Proliferation and Inhibits Cell Apoptosis in Human Glioblastoma	2
Overexpression of BRD4 in Gastric Cancer and its Clinical Significance as a Novel Therapeutic Target	2
Construction of an Oxidative Stress Risk Model to Analyze the Correlation Between Liver Cancer and Tumor Immunity	2
Value of Label-Free Ubiquitin-Proteomic Analysis on Defining the Protective Mechanism of Valsartan against Doxorubicin-Induced Heart Failure	2
WITHDRAWN: Comprehensive Analysis of the Role of CXCL Family Members in Clear Cell Renal Cell Carcinoma	2
IL-33/ST2 Signaling and its Correlation with Macrophage Heterogeneity and Clinicopathologic Features in Human Intrahepatic Cholangiocarcinoma	2
The Potential of Natural Products in the Treatment of Triple-negative Breast Cancer	2
Exosomes Mediate the Production of Oxaliplatin Resistance and Affect Biological Behaviors of Colon Cancer Cell Lines	2
Novel Association of RAD54L Mutation with Müllerian Clear Cell Carcinoma of the Male Urethra: New Insights Regarding the Molecular Mechanisms of a Rare Tumour	2
EWS-RNA Binding Protein 1: Structural Insights into Ewing Sarcoma by Conformational Dynamics Investigations	2
Advances in Understanding How RhoB Regulates Akt Inhibition Efficacy in NSCLC	2
Geiparvarin Inhibits the Progression of Osteosarcoma by Down-regulating COX2 Expression	2
The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets	2
Decoding Metastasis: From Cell Death to Fusion in Cancer Progression	1
Computational Design for Identification of Human Anti-MUC1 Heteroclitic Peptides in the Treatment of HER2-Positive Breast Cancer through Neural Network Training and Monomeric based Design	1
The Tumor Immune Microenvironment plays a Key Role in Driving the Progression of Cholangiocarcinoma	1
Fe3O4-viral-like Mesoporous Silica Nanoparticle(Fe3O4-vMSN)-Sustained Release of Lenvatinib for Targeted Treatment of Hepatocellular Carcinoma	1
Mesenchymal Epithelial Transition (MET): A Key Player in Chemotherapy Resistance and an Emerging Target for Potentiating Cancer Immunotherapy	1
The Role of Vasodilator-stimulated Phosphoproteins in the Development of Malignant Tumors	1
Promotion of Melanoma Progression through MCM4-Induced Immune Suppression and Polarization of Macrophages by Carcinogenic Exosomes	1
Comprehensive Analyses and Experiments Confirmed IGFBP5 as a Prognostic Predictor Based on an Aging-genomic Landscape Analysis of Ovarian Cancer	1
Prognostic Significance and Functional Mechanism of UTS2 in Glioblastoma Multiforme	1
A Potential Role for Oridonin in Cancer Control: Mechanisms of Autophagy and Apoptosis	1
Network Pharmacology-Based Virtual Screening of Chemical Constituents from Vitexnegundo Linn’s Discovered Novel Molecular Targets for Breast Cancer Treatment	1
Pharmacological Inhibition of Exosome Machinery: An Emerging Prospect in Cancer Therapeutics	1
Nanocarrier System for Increasing the Therapeutic Efficacy of Oxaliplatin	1
Inhibitor of Growth 4 (ING4) Plays a Tumor-repressing Role in Oral Squamous Cell Carcinoma via Nuclear Factor Kappa-B (NF-kB)/DNA Methyltransferase 1 (DNMT1) Axis-mediated Regulation of Aldehyde Dehyd	1
Evaluation of the Antitumoral Effect of PI3K/AKT/mTOR Pathway Inhibition and Antioxidant Combination on Burkitt Lymphoma Cell Line	1
A Review of the Progress in the Diagnosis and Treatment of Pulmonary Sarcomatoid Carcinoma	1
Exploring the Antitumor Efficacy of PEGylated Liposomes Loaded with Licorice Extract for Cancer Therapy	1
Envafolimab Inhibits the Growth of Gastric Cancer Cells with Low PD-L1 Expression through the DDX20/NF-κB/TNF-α Signaling Pathway	1
Growth-hormone-releasing Hormone as a Prognostic Biomarker and Therapeutic Target in Gastrointestinal Cancer	1
Advances in Ovarian Cancer Treatment Beyond PARP Inhibitors	1
GRP78 is Overexpressed in Non-small Cell Lung Cancer Tissues and is Associated with High VEGF Expression in Squamous Cell Carcinoma: A Pilot Study	1
Oncolytic Adenovirus H101 Synergizes with Radiation in Cervical Cancer Cells	1
Pharmacological Evaluation of Amorphophalli rhizoma to Inhibit the Progression of Estrogen Receptor+ (ER+) Breast Cancer by Modulating the PI3K/AKT Cell Signaling Pathway	1
Arsenic Trioxide Restrains Lung Cancer Growth and Metastasis by Blocking the Calcineurin-NFAT Pathway by Upregulating DSCR1	1
Anti-Obesity Medications in Cancer Therapy: A Comprehensive Insight	1
Therapeutic Potential of Clostridium novyi-NT in Cancer: Current Knowledge and Future Perspectives	1
Polycaprolactone-based Nanocarriers Containing 5-fluorouracil as a Therapeutic Guided Drug Delivery Approach for Enhancing Anticancer Activity	1
Biomacromolecule-Functionalized Nanoparticle-Based Conjugates for Potentiation of Anticancer Therapy	1
Rediscovering Potential Molecular Targets for Glioma Therapy Through the Analysis of the Cell of Origin, Microenvironment and Metabolism	1
The Therapeutic Potential of Targeting Tumor Microenvironment and Modulation of Immunotherapy in Gastrointestinal Cancer	1
7-Dehydrocholesterol Reductase Activates the Hedgehog Pathway by Regulating Cholesterol to Promote the Development of Triple-Negative Breast Cancer	1
Modulation of ATP8B1 Gene Expression in Colorectal Cancer Cells Suggest its Role as a Tumor Suppressor	1
Early Detection, Precision Treatment, Recurrence Monitoring: Liquid Biopsy Transforms Colorectal Cancer Therapy	1
Immunotherapy for Gastroesophageal Tumors: Is there still Hope for Efficacy?	1
Zinc Finger Protein 536 is a Potential Prognostic Biomarker that Promotes Neuroblastoma Progression via VEGFR2-PI3K-AKT Pathway	1
The Role of Nrf2 in Glioma: Therapeutic Targeting Strategies	1
Cucurbitacin D Inhibits the Proliferation of HepG2 Cells and Induces Apoptosis by Modulating JAK/STAT3, PI3K/Akt/mTOR and MAPK Signaling Pathways	1
YPEL1 Inhibits Development of Gemcitabine Resistance in NK / T Cell Lymphomas	1
Effect of HPV Oncoprotein on Carbohydrate and Lipid Metabolism in Tumor Cells	1
Extraordinary Benefit of Regorafenib in Metastatic Cholangiocarcinoma: A Case Report	1
Increase in Cisplatin Resistance by MeCP2 in Human Gastric Cancer through the Activation of the AKT Pathway by Facilitating PDK-1 Transcription	1
Combined Transarterial Chemoembolization with Microwave Ablation versus Microwave Alone for Treatment of Medium Sized Hepatocellular Carcinoma	1
PIWIL1 Promotes Malignant Progression of Papillary Thyroid Carcinoma by Inducing EVA1A Expression	1
Bromodomain Protein-directed Agents and MYC in Small Cell Lung Cancer	1
Establishment and Validation of a Blood Test-based Nomogram to Diagnose Patients with AFP-negative HCC	1
Competing Risk Analysis for Diabetes Mellitus Mortality in Bladder Cancer Patients: A Population-based Study	1
Wnt/β-catenin Signaling in Lung Cancer: Association with Proliferation, Metastasis, and Therapy Resistance	1
The Mutation and Low Expression of ARID1A are Predictive of a Poor Prognosis and High Immune Infiltration in Triple-negative Breast Cancer	1
Role of Exosomes in Breast Cancer Management: Evidence-Based Review	1
Saikosaponin B4 Suppression Cancer Progression by Inhibiting SW480 and SW620 Cells Proliferation via the PI3K/AKT/mTOR Pathway in Colon Cancer	1
Transforming Cancer Care: The Impact of AI-driven Strategies	1
Low Expression MCEMP1 Promotes Lung Adenocarcinoma Progression and its Clinical Value	1
The Curcumin Analog EF24 is Highly Active Against Chemotherapy- Resistant Melanoma Cells	1
Advancement and Strategies for the Development of Peptide-drug Conjugates: Pharmacokinetic Modulation, Role and Clinical Evidence against Cancer Management	1
Knockdown of ARL5B Induces Mitochondrial-mediated Apoptosis and Inhibits Glycolysis in Breast Cancer Cells by Activating MDA5 Signaling	1