Ageing Research Reviews

Papers
(The H4-Index of Ageing Research Reviews is 75. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Editorial Board477
Medication reviews in hospitalised patients for reduced hospital readmission and mortality. Systematic review, meta-analysis and meta-regression of RCTs427
Does drug repurposing bridge the gaps in management of Parkinson’s disease? Unravelling the facts and fallacies368
Editorial Board244
Roles of hypoxia-inducible factor-prolyl hydroxylases in aging and disease244
Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging and age-related disease241
The unique neuropathological vulnerability of the human brain to aging238
miR-21 and miR-146a: The microRNAs of inflammaging and age-related diseases226
Sarcobesity: New paradigms for healthy aging related to taurine supplementation, gut microbiota and exercise211
Start the engine of neuroregeneration: A mechanistic and strategic overview of direct astrocyte-to-neuron reprogramming207
Rethinking IRPs/IRE system in neurodegenerative disorders: Looking beyond iron metabolism180
Editorial Board172
The functions of IRE1α in neurodegenerative diseases: Beyond ER stress169
Editor’s Note to “Biological constraint, evolutionary spandrels and antagonistic pleiotropy”167
Type 2 diabetes mellitus augments Parkinson’s disease risk or the other way around: Facts, challenges and future possibilities166
DNA methylation in genes associated with the evolution of ageing and disease: A critical review157
Thioredoxin-1 inhibits the activation of IRE1 by targeting Hsp90/p-Cdc37 chaperone complex in Parkinson disease155
Advances in clinical application of lipidomics in healthy ageing and healthy longevity medicine152
CC chemokines family in fibrosis and aging: From mechanisms to therapy151
Microglia and gut microbiota: A double-edged sword in Alzheimer's disease149
Artificial intelligence in brain MRI analysis of Alzheimer’s disease over the past 12 years: A systematic review148
Adenosine metabolism and receptors in aging of the skin, musculoskeletal, immune and cardiovascular systems140
How good is the evidence that cellular senescence causes skin ageing?140
Optimal dose and type of exercise to improve cognitive function in older adults: A systematic review and bayesian model-based network meta-analysis of RCTs138
Advances in Alzheimer's therapy: Exploring neuropathological mechanisms to revolutionize the future therapeutic landscape135
Effectiveness of virtual reality interventions on quality of life, cognitive function and physical function in older people with Alzheimer's disease: A systematic review134
Repetitive transcranial magnetic stimulation combined with cognitive training for cognitive function and activities of daily living in patients with post-stroke cognitive impairment: A systematic revi127
Unraveling the protein post-translational modification landscape: Neuroinflammation and neuronal death after stroke123
Global, regional, and national burden of spinal cord injury from 1990 to 2021 and projections for 2050: A systematic analysis for the Global Burden of Disease 2021 study119
Vascular cognitive impairment – Past, present, and future challenges118
Updated systematic review and meta-analysis on diagnostic issues and the prognostic impact of myosteatosis: A new paradigm beyond sarcopenia116
Prevalence and health outcomes of polypharmacy and hyperpolypharmacy in older adults with frailty: A systematic review and meta-analysis115
Can dementia risk be reduced by following the American Heart Association's Life's Simple 7? A systematic review and dose-response meta-analysis111
Efficacy of technology-based cognitive and exercise interventions for mild cognitive impairment: A systematic review, network meta-analysis, and meta-regression of randomized controlled trials110
Unravelling the brain resilience following stroke: From injury to rewiring of the brain through pathway activation, drug targets, and therapeutic interventions110
The protein inputs of an ultra-predictive aging clock represent viable anti-aging drug targets109
Dysfunction of norepinephrine and its metabolites in Alzheimer's dementia – A review with meta-analysis108
Biomarkers associated with cognitive impairment in post-traumatic stress disorder: A systematic review of current evidence107
Cognitive resilience in Alzheimer’s disease: Mechanism and potential clinical intervention106
The several ways to authentically cure Alzheimer’s dementia106
Interventions to prevent and treat delirium: An umbrella review of randomized controlled trials106
HMGB1, an evolving pleiotropic protein critical for cellular and tissue homeostasis: Role in aging and age-related diseases105
Neuroprotection by agmatine: Possible involvement of the gut microbiome?102
Targeting aging with urolithin A in humans: A systematic review101
Overview of pro-inflammatory and pro-survival components in neuroinflammatory signalling and neurodegeneration101
Advances of artificial intelligence in predicting frailty using real-world data: A scoping review101
Associations of olfactory function with brain structural and functional outcomes. A systematic review100
Involvement of regulated cell deaths in aging and age-related pathologies99
Cytosolic DNA sensor IFI16 proteins: Potential molecular integrators of interactions among the aging hallmarks96
Triaging between post-translational modification of cell cycle regulators and their therapeutics in neurodegenerative diseases96
Role of diet and exercise in aging, Alzheimer’s disease, and other chronic diseases95
On the wake of metformin: Do anti-diabetic SGLT2 inhibitors exert anti-aging effects?95
Bridging neurotrophic factors and bioactive peptides to Alzheimer's disease94
The mitochondrial integrated stress response: A novel approach to anti-aging and pro-longevity92
Potential convergence of olfactory dysfunction in Parkinson’s disease and COVID-19: The role of neuroinflammation90
Exercise training increases telomerase reverse transcriptase gene expression and telomerase activity: A systematic review and meta-analysis87
Betaine and aging: A narrative review of findings, possible mechanisms, research perspectives, and practical recommendations86
Searching for the link between inflammaging and sarcopenia86
Melatonin: Potential avenue for treating iron overload disorders85
Sensory nerve regulation of bone homeostasis: Emerging therapeutic opportunities for bone-related diseases84
Adherence to the Mediterranean diet and risk of frailty and pre-frailty in elderly adults: A systematic review and dose-response meta-analysis with GRADE assessment84
Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: A systematic review and meta-analysis84
The effectiveness of dance movement interventions for older adults with mild cognitive impairment, Alzheimer’s disease, and dementia: A systematic scoping review and meta-analysis82
Modifiable lifestyle factors and cognitive reserve: A systematic review of current evidence82
Characterization of the logopenic variant of Primary Progressive Aphasia: A systematic review and meta-analysis81
The link between metabolic syndrome and Alzheimer disease: A mutual relationship and long rigorous investigation80
Transcranial direct current stimulation combined with motor training for motor symptoms in Parkinson's disease: A systematic review and meta-analysis80
Lipids and lipid metabolism in cellular senescence: Emerging targets for age-related diseases78
Hallmarks of aging: A user’s guide for comparative biologists77
The role of the PLA2G6 gene in neurodegenerative diseases77
Targeting immune dysfunction in aging77
Identification of exosomal biomarkers and its optimal isolation and detection method for the diagnosis of Parkinson's disease: A systematic review and meta-analysis76
Research progress in Alzheimer's disease and bone-brain axis75
Omics sciences for systems biology in Alzheimer’s disease: State-of-the-art of the evidence75
A Multimodal Meta-Analytical Evidence of Functional and Structural Brain Abnormalities Across Alzheimer's Disease Spectrum75
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