Ageing Research Reviews

Papers
(The H4-Index of Ageing Research Reviews is 75. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Editorial Board494
Roles of hypoxia-inducible factor-prolyl hydroxylases in aging and disease380
Editorial Board250
Discovery of a new hereditary RECQ helicase disorder RECON syndrome positions the replication stress response and genome homeostasis as centrally important processes in aging and age-related disease249
The unique neuropathological vulnerability of the human brain to aging248
Rethinking IRPs/IRE system in neurodegenerative disorders: Looking beyond iron metabolism245
Editorial Board232
Start the engine of neuroregeneration: A mechanistic and strategic overview of direct astrocyte-to-neuron reprogramming217
The protein inputs of an ultra-predictive aging clock represent viable anti-aging drug targets210
DNA methylation in genes associated with the evolution of ageing and disease: A critical review198
Thioredoxin-1 inhibits the activation of IRE1 by targeting Hsp90/p-Cdc37 chaperone complex in Parkinson disease193
Medication reviews in hospitalised patients for reduced hospital readmission and mortality. Systematic review, meta-analysis and meta-regression of RCTs182
CC chemokines family in fibrosis and aging: From mechanisms to therapy176
How good is the evidence that cellular senescence causes skin ageing?162
Editor’s Note to “Biological constraint, evolutionary spandrels and antagonistic pleiotropy”160
Type 2 diabetes mellitus augments Parkinson’s disease risk or the other way around: Facts, challenges and future possibilities160
Advances in clinical application of lipidomics in healthy ageing and healthy longevity medicine158
Sarcobesity: New paradigms for healthy aging related to taurine supplementation, gut microbiota and exercise157
Does drug repurposing bridge the gaps in management of Parkinson’s disease? Unravelling the facts and fallacies152
Advances in Alzheimer's therapy: Exploring neuropathological mechanisms to revolutionize the future therapeutic landscape145
Prevalence and health outcomes of polypharmacy and hyperpolypharmacy in older adults with frailty: A systematic review and meta-analysis144
Efficacy of technology-based cognitive and exercise interventions for mild cognitive impairment: A systematic review, network meta-analysis, and meta-regression of randomized controlled trials143
Effectiveness of virtual reality interventions on quality of life, cognitive function and physical function in older people with Alzheimer's disease: A systematic review139
Histopathological and ultrastructural changes in different cell types during ischemic and hemorrhagic stroke139
Updated systematic review and meta-analysis on diagnostic issues and the prognostic impact of myosteatosis: A new paradigm beyond sarcopenia131
Unraveling the protein post-translational modification landscape: Neuroinflammation and neuronal death after stroke131
Unravelling the brain resilience following stroke: From injury to rewiring of the brain through pathway activation, drug targets, and therapeutic interventions131
The functions of IRE1α in neurodegenerative diseases: Beyond ER stress123
Artificial intelligence in brain MRI analysis of Alzheimer’s disease over the past 12 years: A systematic review119
Repetitive transcranial magnetic stimulation combined with cognitive training for cognitive function and activities of daily living in patients with post-stroke cognitive impairment: A systematic revi117
miR-21 and miR-146a: The microRNAs of inflammaging and age-related diseases116
Optimal dose and type of exercise to improve cognitive function in older adults: A systematic review and bayesian model-based network meta-analysis of RCTs113
Adenosine metabolism and receptors in aging of the skin, musculoskeletal, immune and cardiovascular systems113
Vascular cognitive impairment – Past, present, and future challenges112
Dysfunction of norepinephrine and its metabolites in Alzheimer's dementia – A review with meta-analysis111
Microglia and gut microbiota: A double-edged sword in Alzheimer's disease111
Global, regional, and national burden of spinal cord injury from 1990 to 2021 and projections for 2050: A systematic analysis for the Global Burden of Disease 2021 study110
Can dementia risk be reduced by following the American Heart Association's Life's Simple 7? A systematic review and dose-response meta-analysis110
The several ways to authentically cure Alzheimer’s dementia110
Cognitive resilience in Alzheimer’s disease: Mechanism and potential clinical intervention107
Neuroprotection by agmatine: Possible involvement of the gut microbiome?106
Cytosolic DNA sensor IFI16 proteins: Potential molecular integrators of interactions among the aging hallmarks105
Sensory nerve regulation of bone homeostasis: Emerging therapeutic opportunities for bone-related diseases104
Triaging between post-translational modification of cell cycle regulators and their therapeutics in neurodegenerative diseases103
The role of the PLA2G6 gene in neurodegenerative diseases101
Associations of olfactory function with brain structural and functional outcomes. A systematic review100
Biomarkers associated with cognitive impairment in post-traumatic stress disorder: A systematic review of current evidence98
Interventions to prevent and treat delirium: An umbrella review of randomized controlled trials98
Involvement of regulated cell deaths in aging and age-related pathologies97
Overview of pro-inflammatory and pro-survival components in neuroinflammatory signalling and neurodegeneration93
Targeting immune dysfunction in aging93
New era of artificial intelligence and machine learning-based detection, diagnosis, and therapeutics in Parkinson’s disease92
Searching for the link between inflammaging and sarcopenia92
Advances of artificial intelligence in predicting frailty using real-world data: A scoping review91
The effectiveness of dance movement interventions for older adults with mild cognitive impairment, Alzheimer’s disease, and dementia: A systematic scoping review and meta-analysis89
Melatonin: Potential avenue for treating iron overload disorders89
Hallmarks of aging: A user’s guide for comparative biologists86
Transcranial direct current stimulation combined with motor training for motor symptoms in Parkinson's disease: A systematic review and meta-analysis85
Research progress in Alzheimer's disease and bone-brain axis85
A Multimodal Meta-Analytical Evidence of Functional and Structural Brain Abnormalities Across Alzheimer's Disease Spectrum85
On the wake of metformin: Do anti-diabetic SGLT2 inhibitors exert anti-aging effects?84
Characterization of the logopenic variant of Primary Progressive Aphasia: A systematic review and meta-analysis83
The mitochondrial integrated stress response: A novel approach to anti-aging and pro-longevity83
Bridging neurotrophic factors and bioactive peptides to Alzheimer's disease82
Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: A systematic review and meta-analysis81
Role of diet and exercise in aging, Alzheimer’s disease, and other chronic diseases80
Exercise training increases telomerase reverse transcriptase gene expression and telomerase activity: A systematic review and meta-analysis80
Potential convergence of olfactory dysfunction in Parkinson’s disease and COVID-19: The role of neuroinflammation79
Betaine and aging: A narrative review of findings, possible mechanisms, research perspectives, and practical recommendations79
The link between metabolic syndrome and Alzheimer disease: A mutual relationship and long rigorous investigation78
HMGB1, an evolving pleiotropic protein critical for cellular and tissue homeostasis: Role in aging and age-related diseases78
Targeting aging with urolithin A in humans: A systematic review77
Adherence to the Mediterranean diet and risk of frailty and pre-frailty in elderly adults: A systematic review and dose-response meta-analysis with GRADE assessment77
Identification of exosomal biomarkers and its optimal isolation and detection method for the diagnosis of Parkinson's disease: A systematic review and meta-analysis76
Lipids and lipid metabolism in cellular senescence: Emerging targets for age-related diseases75
Modifiable lifestyle factors and cognitive reserve: A systematic review of current evidence75
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