Phytochemistry Reviews

Article	Citations
Phytochemistry, ethnopharmacology and novel formulations based approaches for the treatment of irritable bowel syndrome: a comprehensive review	192
Sulfated flavonoids: An updated and comprehensive review of their chemistry and bioactivities	142
Polyamines: defeat or survival of the fungus	109
Correction: Astaxanthin bioaccumulation in microalgae under environmental stress simulated in industrial effluents highlighting prospects of Haematococcus pluvialis: knowledge gaps and prospective app	98
Navigating the chemical space of natural products from diverse sources: a chemoinformatics perspective	75
Research progress on chemistry, bioactivity, and NMR patterns of acetylene compounds in natural products (2015–2025)	70
Phenylphenalenone-type phytoalexins in banana (Musa species): a comprehensive review for new research directions	66
A systematic review on the research status of quercetagetin: resources, biosynthesis, bioavailability, bioactive-delivery systems, health effects, marketed functional products and patents	46
GC–MS analysis, HPLC–UV analysis, antimicrobial and antioxidant activities of extracts of wild-growing anabasis salsa native to kazakhstan desert iands	45
Chemical composition, nutritional and health related properties of the medlar (Mespilus germanica L.): from medieval glory to underutilized fruit	45
Nutritional immunological effects and mechanisms of chemical constituents from the homology of medicine and food	45
Planar chromatographic super-hyphenations for rapid dereplication	43
The standardization of officinal medicinal plants used in the Eurasian Economic Union: comparison with other pharmacopoeias	41
Natural alternatives targeting psoriasis pathology and key signaling pathways: a focus on phytochemicals	40
From present to prosperity: assessing the current status and envisioning opportunities in the industrial-scale cultivation of Haematococcus pluvialis for astaxanthin production	40
A comprehensive approach to phytochemical analysis of macromolecular composites that protect tubers: case studies in suberized potato periderm tissues	39
Specialized metabolites of the genus Zephyranthes Herb.: a critical review on taxonomy and phytochemistry	35
Comprehensive review of Urtica dioica L. (Urticaceae) phytochemistry and anti-inflammatory properties	34
Silene genus: a review of its traditional uses, phytochemistry and pharmacology	34
Nutraceutical potential of genus Garcinia: A comprehensive review	34
Steroidal saponins in edible and medicinal plants: species distribution, bioactivity, biosynthesis, and regulation	31
Natural antioxidants in the preservation of omega-3-rich oils: applications in bulk, emulsified, and microencapsulated chia, flaxseed, and Sacha inchi oils	31
Clerodendrum inerme (L.) Gaertn.: a critical review on current progress in traditional uses, phytochemistry, pharmacological aspects and toxicity	31
Allelopathy research on the continuous cropping problem of poplar (populus)	30
Evidence of phenolic compounds as modulators of ChREBP and NRF2 in type 2 diabetes: a review of their potential for drug development	30

Exploring plant-derived bisindole alkaloids: a comprehensive review of sources, phytochemistry and cytotoxicity	30
Etlingera Species of Borneo's wild gingers: traditional knowledge, phytochemistry, and modern applications	29
The mechanisms of action of prenylated xanthones against breast, colon, and lung cancers, and their potential application against drug resistance	29
Nanocarrier mediated co-delivery of phytochemicals and chemo-drugs: an emerging strategy to combat lung cancer in a systemic way	28
Beyond traditional uses: the multifaceted bioactivities of steroidal saponins from the genus Trillium and their modern applications	28
Dietary polyphenols ameliorate inflammatory bowel diseases: advances and future perspectives to maximize their nutraceutical applications	28
Comparative structural analysis of plant uridine diphosphate (UDP)-dependent glycosyltransferases (UGTs) in plant specialized metabolism: structures of plant UGTs for biosynthesis of steviol glycoside	27
Correction to: Holothuria triterpene glycosides: a comprehensive guide for their structure elucidation and critical appraisal of reported compounds	27
A review of chemical diversity of Kappaphycus alvarezii: biological properties, health benefits, and food applications	26
Moringa oleifera: a comprehensive review with special emphasis on phytochemistry	25
Carbohydrate metabolic responses to water stress in plants: implications for yield and quality	24
Natural compounds as potential anticancer agents aimed at ovarian cancer stem cells	24
Edible fruits and berries as a source of functional polyphenols: current scene and future perspectives	23
Medicinal plants as a source of active molecules for the Leishmania parasite	22
Plant-derived bioactive compounds as key players in the modulation of immune-related conditions	22
Green decontaminants for the remediation of chemical, biological, radiological and nuclear contaminants	21
Traditional uses and advances in recent research on wild aromatic plant Mentha longifolia and its pharmacological importance	21
The green antidote: phytochemical defense as a natural shield against chemical warfare	20
From phytochemistry to biomaterials: curcumin-based scaffolds in wound management	20
Phytochemicals with anticancer activity from poisonous plants: potential leads for cancer therapy	20
Bioassay-guided studies of mayan origin foods: extraction and clinical relevance of secondary metabolites in the management of CNCDs	19
Cannabis monoterpene synthases: evaluating structure–function relationships	19
Recent advancements in natural compounds for cancer therapy and prevention	19
Natural acylated flavonoids: their chemistry and biological merits in context to molecular docking studies	19
Gmelina asiatica: exploring traditional uses, pharmacological insights, and phytoconstituents—a comprehensive review (1961–2023)	18
Artemisia argyi H. Lév. & Vaniot: a comprehensive review on traditional uses, phytochemistry, and pharmacological activities	18
Image processing and deep learning applications in herbal microscopy: a systematic review	18
Mechanistic insight into anti-inflammatory potential, phytochemistry and ethnomedicinal status of Ilex species: a review	17
Garlic and breast cancer: how far has the research come?	17
Plant flavonoid effects on the non-apoptotic mechanisms of regulated cell death	16
Influence of altitude on the physicochemical composition and antioxidant capacity of strawberry: a preliminary systematic review and meta-analysis	16
Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety	15
Optimizing Pistacia lentiscus (mastic tree) food and healthcare applications: phytochemical composition, extraction methods, quality control, and novel delivery systems	15
Brazilian arnicas: bioactive compounds, pharmacological properties, potential use and clinical applications	15
Subcritical water extractions to obtain plant volatile compounds: challenges and opportunities for the essential oils industry	15
Hordatines, dimerised hydroxycinnamoylagmatine conjugates of barley (Hordeum vulgare L.): an appraisal of the biosynthesis, chemistry, identification and bioactivities	15
Advances on resource, biosynthesis pathway, bioavailability, and bioactivity of dihydrodaidzein	14
Pharmacodynamics, pharmacokinetics, and cell signaling pathways of pomegranate peel extract	14
Unraveling the molecular mechanisms of melon fruit firmness: insights into cell wall gene expression and regulation	14
Phytomedicine approach for management of diabetes mellitus: an overview of scientifically confirmed medicinal plants with hypoglycaemic properties and their probable mechanism of action	13
Unravelling the chemical and pharmacological contour of plants of the genus Duguetia A. St.-Hil. (Annonaceae): a mini-review	13
A comprehensive insight on the bioactive phytochemicals and pharmacological propensities of Ficus benghalensis L.: a reservoir for modern drug discovery	13
The call of the wild hops: chemical diversity of Humulus species and their use in brewing	13
Phytopharmacological aspects of Mimosa tenuiflora (Willd.) poir.: a systematic review of preclinical data	13
Emerging functions within the enzyme families of plant alkaloid biosynthesis	13
Plant flavonoids bioavailability in vivo and mechanisms of benefits on chronic kidney disease: a comprehensive review	13
The uneven molecular distribution: a connection with plant functioning and stress resilience	13
Research progress on the chemical composition changes of traditional Chinese medicine before and after processing based on modern analytical techniques	12
Phytochemical and pharmacological properties of Xanthium species: a review	12
Moringa 360: a comprehensive review of its nutritional, medicinal and industrial brilliance	12

Hesperidin: a flavanone with multifaceted applications in the food, animal feed, and environmental fields	12
Mass spectrometry imaging: an emerging technology in plant molecular physiology	12
Secondary metabolites of desert and stress-adapted plants: adaptive responses toward salinity and drought stresses, and optimization tools and techniques	12
Mechanisms of action of natural plant-derived bioactive compounds in treating intestinal tight junctions dysfunction	12
Application of molecular imprinting approach for alkaloids analysis in food and nutraceuticals: review and perspective	12
Mechanistic insights into therapeutic potential of Centella asiatica (L.) Urb.in diabetes mellitus and its chronic health complexities: from botany, medicinal chemistry to clinical trials approach	12
A review on the genus Melodinus: traditional uses, phytochemical diversity and pharmacological activities of indole alkaloids	11
“C-phycocyanin from cyanobacteria: a therapeutic journey from antioxidant defence to diabetes management and beyond”	11
Australian tropical medicinal plants and their phytochemicals with wound healing and antidiabetic properties	11
Hormetic action of cyanide: plant gasotransmitter and poison	11
Modern research progress on extraction and purification, pharmacological activity, toxicology, pharmacokinetics and carrier new dosage forms of ophiopogonin	11
The metabolites of Piper sarmentosum and their biological properties: a recent update	11
Isoquinoline alkaloids from Amaryllidaceae plants as potential agents against neglected tropical diseases: a review from 2019 to 2025	11
Guest editorial: special issue on “Microalgae biorefinery: current bottlenecks, challenges, and future directions”	11
Advances in natural products with anti-skin photoaging: mechanisms, phytochemical diversity, and therapeutic potential	11
Safety concern of drugs of herbal origin	11
Role of bioactive phytochemicals in plant seeds and leaves for diabetes control and prevention: a comprehensive review	11
Advances and challenges in Paeoniae Radix Rubra research from 2014 to 2024: the botany, phytochemistry, pharmacology, and application	10
The anticancer properties of harmine and its derivatives	10
Synthesis and physiological function of lignin in the reproductive structures of angiosperms	10
Phytochemistry and pharmacological activities of Tadehagi triquetrum (L.) H. Ohashi, an Asian medicinal plant: a comprehensive review	10
Natural products: protective effects against sensorineural hearing loss	10
Synthetic strategies and pharmacological insights into Boswellic acid-hybrid based therapeutics	10
Where are you heading to, Cannabis research?	10
Phytochemistry, pharmacology and bibliometrics insight of the genus Callicarpa L.: an extensive review encompassing the years from approximately 2010 to 2024	9
Reflecting on the interesting phytopharmacology of the cosmopolitan Dodonaea genus: past, present and future	9
Advancing alkaloid-based medicines: medical applications, scalable production and synthetic innovations	9
Bio revolution of green polymers: advancing the circular bioeconomy via bio-sourced biopolymers, from extraction to diverse applications and sustainability assessment	9
Terpenoids and sterols from lichens	9
Bioactivity and application of anthocyanins in skin protection and cosmetics: an extension as a functional pigment	9
Advanced high-resolution chromatographic strategies for efficient isolation of natural products from complex biological matrices: from metabolite profiling to pure chemical entities	9
A comprehensive review of supernatural coriander herb (Coriandrum sativum): phytochemical insights, pharmacological potential and future perspective	9
A critical review on Pulicaria species occurring in Qatar: traditional uses, phytochemistry and biological activities	9
Exploring the medicinal potential of Lantana camara: a comprehensive review of phytochemicals and therapeutic application	8
Diterpenoids from Euphorbia lathyris L.: a comprehensive review update	8
Research progress on chemical constituents from Curcumae Rhizoma, and their pharmacological activity and biosynthesis	8
Ethanopharmacological relevance of Cuscuta reflexa Roxb. and its role as a hepato-protective agent: a comprehensive review	8
An extensive analysis of the biochemical dimensions of phytochemicals in the treatment or prevention of breast cancer	8
Auraptene: a survey of the last three years of intense research	8
Ecological and environmental determinants of phytochemical variability in forest trees	8
Natural therapies: a systematic review of the medicinal applications of Passiflora ligularis	8
Enhancing the therapeutic potential of Pistacia extracts: a review of nanocarrier-based strategies	8
Green messengers: the role of catecholamines in plants	8
Biofuel production from microalgae: challenges and chances	8
Sustainable extraction methods for the recovery of polyphenolic compounds from grape pomace and its biological properties: a comprehensive review	8
Pro-drug approaches to overcome poor solubility and toxicity of triptolide	7
Phytochemicals in medicine and food: potential to the development of health products in medicine and food industries	7
Ameliorative role of bioactive phytoconstituents targeting obesity associated NAFLD by modulation of inflammation and lipogenesis pathways: a comprehensive review	7
Exploration of ethnomedicinal plants of Western Himalayas used in the management of gastrointestinal disorders	7
Traditional Chinese medicine and natural small molecules for pain treatment via voltage-gated sodium channels: a review	7
Flavanones: bioavailability and role in modulation of oxidative stress and inflammation in cancer, type-2 diabetes, and cardiovascular diseases	7
Is telomerase a hidden player? Therapeutic potential of natural telomerase activators against age-related diseases	7
Vascular targeting of constituents of commonly used spices and its molecular interactions in endothelial dysfunction: A review	7
Bioactive compounds of Piper chaba and their pharmacological relevance: a phytochemistry-focused review	7
Proanthocyanidin biosynthesis and postharvest seed coat darkening in pinto bean	7
Phytochemical treasure troves—insights into bioactivities, phytochemistry, and uses of Artemisia species	7
Fruit juices: chemical compositions and health benefits	7
Therapeutic potential of phytochemicals against breast cancer: current status and future perspectives	7
Metabolomics applications in natural cosmetics: addressing the new challenges of bio-sourced ingredients	7
Microalgae as a source of carotenoids in foods, obstacles and solutions	7
Insights into Pinus species: phytochemistry, pharmacology and industrial potential of Indian Pinus species	7
Phytochemistry and pharmacology of the Brazilian cherry (Eugenia involucrata, Myrtaceae): a systematic review	6
Chalcone and derived natural products: versatile scaffolds for multiple targets in treatment of Type 2 diabetes	6
Quantitative analysis of epigallocatechin-3-gallate in treating renal injury via meta-analysis and machine learning	6
Little-known Saniculeae genera: phytochemical studies and pharmaceutical activities	6
Phytolaccae Radix: a comprehensive review of traditional uses, chemical compositions, pharmacology, toxicology, and pharmacokinetics	6
Update on Brazilian essential oils with leishmanicidal activity	6
Exploring the therapeutic potentials of cuminaldehyde: a comprehensive review of biological activities, mechanisms, and novel delivery systems	6
Epiphytic microbes induced defensive phytochemicals against insects	6
An updated and comprehensive review on the ethnomedicinal uses, phytochemistry, pharmacological activity and toxicological profile of Tinospora crispa (L.) Hook. f. & Thomson	6
Ferruginol as multifunctional abietane diterpenoid-comprehensive pharmacological evaluation and computational drug discovery insight	6
Chemodiversity of terpenoids from Inuleae tribe species (Asteraceae)	6
Five Himalayan weeds as potential bioresources for bioactive agents: toxic compounds to valuable scaffolds	6
Correction: Ecological and environmental determinants of phytochemical variability in forest trees	6
Bioactive plant compounds and exercise: from molecular mechanisms to clinical applications	6
Recent advancements in citral research: a comprehensive bibliometric overview and review of agricultural applications and future directions	6
Nitrogen-containing metabolites in the Crassulaceae family: structures, biological activities, occurrence and phylogeny	6
Wine industry by-products as a source of active ingredients for topical applications	6
Untangling the rhizosphere specialized metabolome	6
Vigna mungo (Linn.) Hepper: ethnobotanical, pharmacological, phytochemical, and nutritious profile	6

The epigenetic regulation between dietary bioactives and DNA methylation via multiple pathways	6
The potential of Dalbergia sissoo: exploring its phytochemical diversity, pharmacological and biomass applications	6
Accessible versatility underpins the deep evolution of plant specialized metabolism	6
A systematic review on biosynthesis, bioactivities, and therapeutic potential of Spinosin	6
A scientific data-driven review of natural product genipin for disease therapy	5
Pentacyclic triterpenoids: diversity, distribution and their propitious pharmacological potential	5
Correction to: A comprehensive review on various carcinogenic aspects of N-nitrosopiperidine (NPIP)	5
Violaceae: chemical constituents, traditional use and pharmacology	5
Biological properties and potential of compounds extracted from red seaweeds	5
A comprehensive update on cannabidiol, its formulations and drug delivery systems	5
A comprehensive review of the phytochemical and pharmacological attributes of Coronopus didymus	5
Ramulus Rubi: a systematic overview on phytochemistry and pharmacology of an important traditional Mongolian medicine	5
Review of natural plant-derived seco-triterpenoids and derived saponins from 2020 to 2023: new compounds, distributions, diverse activities and structure–activity relationships	5
Scratching the surface: The diversity and roles of triterpenoids in plant cuticular waxes	5
Anthracene derivatives of Asphodelaceae plants and their biological activities	5
Antibacterial activity of Garcinia spp. by molecular docking simulations: an overview	5
Sea buckthorn (Hippophae rhamnoides L.) and its potential as functional food: a comprehensive review on its chemistry, pharmacological, and industrial importance	5
Enzyme-mediated adaptation of herbivorous insects to host phytochemicals	5
Plant–pathogen interaction: chemical mediation in plant signalling and defence	5
Nanoparticles as new elicitors for the production of bioactive and phytochemicals in vitro and in vivo plant culture	5
A systematic review of the botany, ethnopharmacology, quality control, phytochemistry, pharmacology and pharmacokinetics of Corydalis yanhusuo	5
Critical review and future perspectives on the anticancer effects of Stephania tetrandra S. Moore	4
Diterpenoid compounds derived from meliaceae plants and biological activities	4
The current status on secondary metabolites produced by fungi of the genus Diplodia associated with plants	4
Utilizing wastewater and flue gas for enhancing biomass and high-value products from microalgae	4
Agarwood as a neuroprotective agent: a comprehensive review of existing evidence and potential avenues for future research	4
Overview of phytochemical composition and bioactivity of Lavandula species	4
Secondary metabolites from cyanobacteria: source, chemistry, bioactivities, biosynthesis and total synthesis	4
Botany, traditional uses, phytochemistry, pharmacological activities, and toxicity of the mangrove plant Avicennia marina: a comprehensive review	4
An update on chemistry and bioactivities of secondary metabolites from the marine algal-derived endophytic fungi	4
Exploring sources, extraction techniques and food applications: a review on biocolors as next-generation colorants	4
Unravelling the nutraceutical and therapeutic perspectives of corosolic acid: Journey so far and the road ahead	4
Metabolomics in guava: a comprehensive review of quality, agricultural traits, composition, and nutraceutical applications of Psidium guajava fruits and byproducts	4
Efficacy of antidiabetic plants available in Himachal Pradesh in management of diabetes: a comprehensive review	4
Mitigating ROS signalling pathway-mediated defence mechanism: a novel approach to counteract bacterial resistance using natural antioxidant-based antibiotics	4
Specialized metabolites from plants as a source of new multi-target antiviral drugs: a systematic review	4
Unlocking the neuroprotective secrets of natural products: a focus on the gut-brain axis	4
A comprehensive review on phytochemistry, pharmacology, preclinical, and clinical trials of Cydonia oblonga	4
Chemical and biological properties of Mentha × villosa Huds. (mojito mint) and its parental species—Mentha spicata L. (spearmint) and Mentha suaveloens Ehrh. (apple mint)—a review	4
Conferone: a comprehensive review of sources, extraction, characterization, biological and medicinal activities	4
Enhanced anti-inflammatory activity of 4-piperidone-based curcumin analogues: structure–activity relationships and mechanistic insights	4
Antiviral mechanisms of dietary polyphenols: recent developments as antiviral agents and future prospects in combating Nipah virus	4
A systematic review on phytochemical constituents, pharmacological properties and ethnic uses of Ailanthus excelsa Roxb	4
Natural retrochalcones: rare compounds with diverse biological activities	4
Flavonoids as a phytobiotic agent: sources, classifications, biological benefits, and useful impacts on broilers and layers	4
Exploring the therapeutic potential of Thalictrum foliolosum DC: a comprehensive review on its natural products, bioactivity and conservation strategies	4
A comprehensive review on various carcinogenic aspects of N-nitrosopiperidine (NPIP)	4
Prediction of the reaction mechanisms of sesquiterpene coumarin synthases supports a direct evolutionary link with triterpene biosynthesis	4
Stimulating secondary compound accumulation by elicitation: Is it a realistic tool in medicinal plants in vivo?	3
Taxonomic significance of coumarins in species from the subfamily Mutisioideae, Asteraceae	3
Essential oils: antimicrobial, antioxidant properties, and their applications in food preservation—a comprehensive review	3
Insights to therapeutic potentials, pharmaceutical formulations, chemistry and analytical methods of catechin	3
Phytochemistry, data mining, pharmacology, toxicology and the analytical methods of Cyperus rotundus L. (Cyperaceae): a comprehensive review	3
A comprehensive review on the ethno-medicinal and pharmacological properties of Terminalia chebula fruit	3
Eleutherococcus giraldii (Harms) Nakai: a review of botany, traditional uses, phytochemistry, pharmacology and quality control	3
Recent advances on anti-diabetic potential of pigmented phytochemicals in foods and medicinal plants	3
The chemical constituents, biological activities, ecological functions and applications of Dicranopteris Bernh.: a review	3
Strigolactones: diversity, perception, and hydrolysis	3
The structure and bioactivities of Stemona alkaloids and alkaloids with [1,2-α] azepine nucleus (2009–2021)	3
Nutrients and polyphenols-rich Sorghum bicolor genotypes as complementary therapy for Alzheimer’s disease	3
Molecular insights of diabetic nephropathy and chemical constituents-based treatment approach	3
Karanjin: a potential furanoflavonoid for neuroprotection	3
Biological activities of hydroxyanthracene derivatives (HADs) from Aloe species and their potential uses	3
Sustainable solutions to antibiotic resistance: a comprehensive review of plant-derived carbon dots and phytochemicals as innovative antibacterial agents	3
Botanical specifications, ethnobotany, phytochemistry, and pharmacology of herb Digera muricata (L.) Mart: a systematic review	3
A systematical review on ethnobotanical, phytochemical and pharmacological aspects of Dendrobium nobile Lindl.	3
Glucosinolates, isothiocyanates, and their role in the regulation of autophagy and cellular function	3
Regulation of ferroptosis with natural compounds: potential applications in the treatment of acquired brain injury	3
Comprehensive overview of glucosinolates in crucifers: occurrence, roles, metabolism, and transport mechanisms—a review	3
Comprehensive review of the skin use of bakuchiol: physicochemical properties, sources, bioactivities, nanotechnology delivery systems, regulatory and toxicological concerns	3
Herbal therapies for pain management: a scoping review of the current evidence	3
Encapsulated phenolic compounds: clinical efficacy of a novel delivery method	3
Medicinal plants cultivated in Egypt with anticancer potential; a systematic review	3
Aroma Alchemy: Uridine diphosphate-dependent glycosyltransferases mediated regulation of fruit aroma and flavor biosynthesis	3
The potential of ginsenosides from Panax ginseng against the NLRP3 inflammasome	3
A comprehensive review of phytochemistry, biological activities, and applications of Zanthoxylum bungeanum	3
Degraded limonoids: biologically active limonoid fragments re-enhancing interest in Meliaceae and Rutaceae sources	3
A comprehensive insight into the ethnopharmacology, phytochemistry and therapeutic profile of Moringa oleifera Lam.	3
Appraisal of the pleiotropic signaling effects of phytopigments in glioma therapy: an evidence-based mechanistic overview	3
Unlocking the power of sesquiterpenoids: phytochemistry and bioactivities in Artemisia (2017–2023)	3
The multifaceted benefits of Morus nigra L.: a pharmacological powerhouse	3
The antidepressant potential of saffron (Crocus sativus L.): molecular mechanisms, neurotransmitter modulation, gut-brain axis interactions, and clinical efficacy in major depressive disorder	3
Cannabis sativa in South Africa: history, legislation, production, and pharmacological aspects	3
Diospyrin: biosynthesis, distribution in the plant kingdom, and therapeutic potential	3
Chemistry and toxicity of 7-hydroxymitragynine (7-OHMG): an updated review on the oxidized derivative of mitragynine	3
The anti-tumor mechanism and epigenetic effects of bioactive components in saffron	3
The genus Pittosporum: current knowledge on traditional use, phytochemistry, and pharmacological activity	3
Algal lipids for biofuel production: strategies, environmental impacts, downstream processing and commercialization	3
Different delivery systems for improving the bioavailability of ginger bioactive compounds: a comprehensive review	3
A review of Juniperus rigida Sieb. et Zucc.: a potential supplier of bioactive compounds and medical outcomes	3
Mint (Mentha spp.) essential oil extraction: from conventional to emerging technologies	3