OOIR: Observatory of International Research

Papers

(The TQCC of DNA Repair is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
To divide or not to divide? NAC8 (SOG1) as a key regulator of DNA damage response in barley (Hordeum vulgare L.)	77
Editorial Board	74
The nucleotide excision repair proteins through the lens of molecular dynamics simulations	71
Suppressors of Blm-deficiency identify three novel proteins that facilitate DNA repair in Ustilago maydis	70
Catalytic activity of OGG1 is impaired by Zinc deficiency	54
Structural features of DNA polymerases β and λ in complex with benzo[a]pyrene-adducted DNA cause a difference in lesion tolerance	47
The Eyes Absent family: At the intersection of DNA repair, mitosis, and replication	43
The role of DNA damage response in chemo- and radio-resistance of cancer cells: Can DDR inhibitors sole the problem?	41
Editorial Board	41
Editorial Board	39
Chemopotentiating effects of low-dose fractionated radiation on cisplatin and paclitaxel in cervix cancer cell lines and normal fibroblasts from patients with cervix cancer	34
The life and legacy of Sam Wilson (1939–2021)	34
Editorial Board	33
Mechanism for R-loop formation remote from the transcription start site: Topological issues and possible facilitation by dissociation of RNA polymerase	31
Editorial Board	30
Editorial Board	30
From fluorescent foci to sequence: Illuminating DNA double strand break repair by high-throughput sequencing technologies	29
Editorial Board	28
Editors’ Note	28
Cutting-edge Perspectives in Genome Maintenance IX	28
Editorial Board	26
C. elegans ribosomal protein S3 protects against H2O2-induced DNA damage and suppresses spontaneous mutations in yeast	25
Editorial Board	25
The ataxia-telangiectasia mutated gene product regulates the cellular acid-labile sulfide fraction	23
Cockayne syndrome group B protein uses its DNA translocase activity to promote mitotic DNA synthesis	23

DNA polymerase δ: A single Pol31 polymorphism suppresses the strain background-specific lethality of Pol32 inactivation in Saccharomyces cerevisiae	22
Functional defects of cancer-associated MDC1 mutations in DNA damage repair	21
Histone variants H3.3 and H2A.Z/H3.3 facilitate excision of uracil from nucleosome core particles	21
Toxic R-loops: Cause or consequence of replication stress?	21
Cyclin-dependent kinase inhibitors (CDKIs) and the DNA damage response: The link between signaling pathways and cancer	21
Active genome integrity	21
Spatial mapping of the DNA adducts in cancer	20
Human translesion DNA polymerases ι and κ mediate tolerance to temozolomide in MGMT-deficient glioblastoma cells.	19
NEIL3: A unique DNA glycosylase involved in interstrand DNA crosslink repair	19
How DNA damage and non-canonical nucleotides alter the telomerase catalytic cycle	19
Cdc48/p97 segregase: Spotlight on DNA-protein crosslinks	19
Heterogeneity of DNA damage incidence and repair in different chromatin contexts	18
Loss of an ABC transporter in Arabidopsis thaliana confers hypersensitivity to the anti-cancer drug bleomycin	18
Increased contribution of DNA polymerase delta to the leading strand replication in yeast with an impaired CMG helicase complex	18
Histone and Chromatin Dynamics Facilitating DNA repair	17
Transcription and genome integrity	17
MicroRNAs and the DNA damage response: How is cell fate determined?	17
Species variations in XRCC1 recruitment strategies for FHA domain-containing proteins	17
The RNF8 and RNF168 Ubiquitin Ligases Regulate Pro- and Anti-Resection Activities at Broken DNA Ends During Non-Homologous End Joining	17
A novel role for Mms2 in the control of spontaneous mutagenesis and Pol3 abundance	17
BCLAF1, a functional partner of BACH1, participates in DNA damage response	17
Impacts of chromatin dynamics and compartmentalization on DNA repair	17
Synergistic effects on mutagenicity of tandem lesions containing 8-oxo-7,8-dihydro-2′-deoxyguanosine or Fapy•dG flanked by a 3′ 5-formyl-2′-deoxyuridine in human cells	17
Transcription reprogramming and endogenous DNA damage	16
DNA polymerase λ Loop1 variant yields unexpected gain-of-function capabilities in nonhomologous end-joining	16
Mechanistic insights from high resolution DNA damage analysis to understand mixed radiation exposure	16
UV light-induced dual promoter mutations dismantle the telomeric guardrails in melanoma	16
The role of rRNA in maintaining genome stability	16
Helicase activities of Rad5 and Rrm3 genetically interact in the prevention of recombinogenic DNA lesions in Saccharomyces cerevisiae	15
Frailty, sex, and poverty are associated with DNA damage and repair in frail, middle-aged urban adults	15
PARP1-mediated PARylation of TonEBP prevents R-loop–associated DNA damage	15
Mitochondrial apurinic/apyrimidinic endonuclease Apn1 is not critical for the completion of the Plasmodium berghei life cycle	15
Revisiting the BRCA-pathway through the lens of replication gap suppression	14
A-T neurodegeneration and DNA damage-induced transcriptional stress	14
Regulatory apoptotic fragment of PARP1 complements catalytic fragment for PAR and DNA-dependent activity but inhibits DNA-induced catalytic stimulation of PARP2	14
The FAcilitates Chromatin Transcription (FACT) complex: Its roles in DNA repair and implications for cancer therapy	14
Defects in DNA damage responses in SWI/SNF mutant cells and their impact on immune responses	14
The hidden elephant: Modified abasic sites and their consequences	14
Timely upstream events regulating nucleotide excision repair by ubiquitin-proteasome system: ubiquitin guides the way	14
USP13 regulates the replication stress response by deubiquitinating TopBP1	13
Live cell transcription-coupled nucleotide excision repair dynamics revisited	13
A moving target for drug discovery: Structure activity relationship and many genome (de)stabilizing functions of the RAD52 protein	13
Novel insights into bulky DNA damage formation and nucleotide excision repair from high-resolution genomics	13
PARP1: Structural insights and pharmacological targets for inhibition	13
Divergent structures of Mammalian and gammaherpesvirus uracil DNA glycosylases confer distinct DNA binding and substrate activity	13
Editorial Board	12
Editorial Board	12
Functions of PMS2 and MLH1 important for regulation of divergent repeat-mediated deletions	12
Editorial Board	12
Potential cGAS-STING pathway functions in DNA damage responses, DNA replication and DNA repair	12

The Shu complex is an ATPase that regulates Rad51 filaments during homologous recombination in the DNA damage response	12
The burden of overweight: Higher body mass index, but not vital exhaustion, is associated with higher DNA damage and lower DNA repair capacity	12
Bulk synthesis and beyond: The roles of eukaryotic replicative DNA polymerases	12
Acetylation of H3K56 orchestrates UV-responsive chromatin events that generate DNA accessibility during Nucleotide Excision Repair	11
Genetic polymorphisms in DNA repair genes and hepatocellular carcinoma risk	11
Editorial Board	11
Editorial Board	11
Editors’ note on “p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1”	11
Editorial Board	10
The C-terminal tail of Rad17, iVERGE, binds the 9‒1‒1 complex independently of AAA+ ATPase domains to provide another clamp–loader interface	10
Contents of previous 3 special issues in this series of perspectives	10
Editorial Board	10
Editorial Board	10
Multifunctional properties of Nej1XLF C-terminus promote end-joining and impact DNA double-strand break repair pathway choice	10
Contents of previous 3 special issues in this series of perspectives	10
Editorial Board	10
Presenilin-1, mutated in familial Alzheimer’s disease, maintains genome stability via a γ-secretase dependent way	10
Monitoring DNA polymerase β mitochondrial localization and dynamics	10
Plasmodium Ape1 is a multifunctional enzyme in mitochondrial base excision repair and is required for efficient transition from liver to blood stage infection	9
Multi-scale cellular imaging of DNA double strand break repair	9
RNA helicase, DDX3X, is actively recruited to sites of DNA damage in live cells	9
The N-terminal domain of uracil-DNA glycosylase: Roles for disordered regions	9
HOTAIR beyond repression: In protein degradation, inflammation, DNA damage response, and cell signaling	9
An open-source platform to quantify subnuclear foci and protein colocalization in response to replication stress	9
Single-molecule imaging of genome maintenance proteins encountering specific DNA sequences and structures	9
CST in maintaining genome stability: Beyond telomeres	9
Impact of DNA sequences on DNA ‘opening’ by the Rad4/XPC nucleotide excision repair complex	9
CometChip enables parallel analysis of multiple DNA repair activities	8
Non-canonical function of nuclear PTEN and its implication on tumorigenesis	8
Histone lysine modifying enzymes and their critical roles in DNA double-strand break repair	8
UVSSA facilitates transcription-coupled repair of DNA interstrand crosslinks	8
Chaperoning histones at the DNA repair dance	8
Paradoxical role of the major DNA repair protein, OGG1, in action-at-a-distance mutation induction by 8-oxo-7,8-dihydroguanine	8
Phosphoregulation of the checkpoint kinase Mec1ATR	8
DEF1: Much more than an RNA polymerase degradation factor	8
Replication dependent and independent mechanisms of GAA repeat instability	8
DNA damage-induced sumoylation of Sp1 induces its interaction with RNF4 and degradation in S phase to remove 53BP1 from DSBs and permit HR	8
Modulation of immune responses by DNA damage signaling	8
Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhances alkylating agent and PARG inhibition induced cytotoxicity	8
Fanconi anemia and Aldehyde Degradation Deficiency Syndrome: Metabolism and DNA repair protect the genome and hematopoiesis from endogenous DNA damage	7
The roles of TonEBP in the DNA damage response: From DNA damage bypass to R-loop resolution	7
Kinome-wide screening uncovers a role for Bromodomain Protein 3 in DNA double-stranded break repair	7
The analysis of protein recruitment to laser microirradiation-induced DNA damage in live cells: Best practices for data analysis	7
Exploring factors influencing choice of DNA double-strand break repair pathways	7
Single-molecule approaches for DNA damage detection and repair: A focus on Repair Assisted Damage Detection (RADD)	7
UvrD-like helicase Hmi1 Has an ATP independent role in yeast mitochondrial DNA maintenance	7