OOIR: Observatory of International Research

Papers

(The TQCC of Letters in Organic Chemistry is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Dibromination of Cinnamamides with CBr4 Under Mild Conditions	22
Preparation and Adsorption Properties of Polymer Particles based on N, N, N', N'-Tetrakis(4-aminophenyl)-1,4-Benzenediamine	20
Computational Screening of Phytochemicals in Eupatorium adenophorum Extracts for Modulating Blood Coagulation: A Pharmacoinformatics Study	19
α,α-Dibromoketones as Synthetic Equivalents of α-Bromoketones for the Synthesis of Thiazolo[3,2-a]benzimidazoles	16
Chemoselectivity Profiling in the Alkylation of 2-Chloroethylurea Derivatives with Secondary Amines	16
Biomass-Derived Reaction Media Towards the Iodination of Anilines Under the Catalytic Influence of Magnetically Separable Pd@rGO-CuFe2O4	15
Advances in the Arena of 1-(4-hydroxy-6-Methyl-2H-Pyran-2-On-3-yl)- 3-Arylpropenone: Preparation, Reactivity and Transformations	15
Humic Acid as a Recyclable Green Catalyst for the Synthesis of Imines from Carbonyl Compounds and Primary Amines at Room Temperature	15
A Novel Study on Antioxidant Activity and Catalytic Reduction of Methylene Blue using ZnO Nanoparticles Synthesized via the Middle Part of Walnut Shell (Juglans regia) Extract	12
On Water Synthesis of 3-Aryl-5,7-dimethyl-1,2,4-triazolo[4,3-a]pyrimidines using Iodobenzene Diacetate	11
A New Bioactive Thiazolidinone-based Azo Dye for Naked-eye Colorimetric Detection of Cyanide Ions	11
Butadiene Sulfone-catalyzed Monobromination of Arenes with NBS as the Bromination Source: A Simple, Mild, Efficient, and Chemoselective Protocol	11
Miscellaneous Passerini Reaction for α-Acyloxy Carboxamide: Synthesis and Process Optimization Study	10
Phytochemical Study: Molecular Docking of Eugenol Derivatives as Antioxidant and Antimicrobial Agents	10
The Biological and Pharmacological Potentials of Indole-based Heterocycles	10
Docking and Simulation Studies on Novel Analogues of 3,4,5-Trihydroxy Benzoic Acid as HSP90Alpha Inhibitors	9
An improved synthesis of Karahanaenone	9
Semisynthesis and DFT Study of New Michael Adducts using (E)-α-Atlantone, Isolated from Cedrus atlantica Essential Oil	9
A Simple and Efficient Path for the Synthesis Antineoplastic Agent (2R,3R,4S,5R)-5-(6-Amino-2-Chloropurin-9-yl)-4-Fluoro-2-(Hydroxymethyl) oxolan-3-ol (Clofarabine)	9
Antimycobacterial Assessment and Microwave-assisted Synthesis of 2-aryl- 3-(4-methylphenylamino)thiazolidin-4-one Derivatives	9
Continuous-flow Synthesis of Ruthenium Nanoparticles using a Microreactor for the Selective Hydrogenation Reaction	9
Ultrasound-accelerated Synthesis of N-protected Amino Alkyl Iodides from Amino Alcohols Using P2I4 Reagent and its Application in the Synthesis of Amino Alkyl Thiols	8
A Brief Review Depending on the Chemistry of Isatin in Single Pot Technique Towards the Construction of Significant and Valuable Heterocyclic Scaffolds	8
Studies Towards the Synthesis of the Pyrido[1,2-a]azepine Alkaloids	8
β-CD/Lewis Acid Dual Catalytic System for Efficient Synthesis of Pyranopyrazoles in Aqueous Environment	8

Direct Utilization of Waste Glycerol from Biodiesel Production for the Synthesis of Perimidines	8
Apigenin Bioisosteres: Synthesis and Evaluation of their Antioxidant, Antimicrobial, and Anticancer Activities	7
The Nonlinear Optical Properties of Ferrocene-containing Metalloporphyrins Toward the Pico-second Laser	7
Structural Elucidation, In vitro and In silico Biological Evaluations of New Fluorinated Chalcone Derivatives for Potential Antioxidant Activity	7
Development of an Efficient Process for a Diagnostic Test Agent (Bentiromide) and Identification, Synthesis, Characterization, and Control Strategy for Potential Impurities	7
Efficient Monoalkylation of Anilines with Chalcones using Microwave-Assisted aza-Michael Addition	7
Nickel-Catalyzed Coupling Reaction of Arylboronic Acid with Methyl Dithiocarbamates for the Synthesis of Thioamides	7
In Silico Exploration of Flavonoids as SPPV14 Inhibitors: Potential Antiviral Agents for Sheep Pox Virus	7
Synthesis of Methyl N-phenylcarbamate Derivatives by Xphos Pd G2 Catalyzed Intermolecular Amidation Reaction	6
A Review on Diverse Biological Activity of Heterocyclic Nucleus Pyrazine and its Derivatives: A Key for the Researchers	6
Structure-Activity Design, Synthesis and Biological Activity of Newer Imidazole- Triazine Clubbed Derivatives as Antimicrobial and Antitubercular Agents	6
Synthesis, Characterization, and Toxicity Studies of Azo Dye Ligand for Metal Assessment in Different Brands of Lipsticks in Iraq	6
A Novel Powerful γ-Fe2O3 @ CPTMS - Diethylene Triamine (DETA) @SO3H as a Heterogeneous Nanocatalyst, Recyclable and Efficient via Microwave-assisted for the Synthesis of Benzoxazinone- 4(3H)-one Deriv	6
Preface	6
Insights Into the Synthetic Strategies, Biological Activity, and Structure- Activity Relationship of Pyridine and Analogs: A Review	6
Ionic liquid Supported Quinuclidine Catalyzed Morita-Baylis-Hillman Reaction	5
Oxidative Coupling: An Important Tool for Pyrrole Synthesis	5
The Miraculous of Rhizopus arrhizus in the Structural Modifications of Steroidal Skeleton	5
Fe₃O₄@TiO₂ Magnetic Nanocomposite Catalyzed Sustainable Synthesis of Dihydro[1]benzopyrano[h][1]benzopyrans and Antimicrobial Activity Evaluation	5
A Green and Convenient Approach for the Synthesis of Indole-acrylonitrile and Indole-coumarin Hybrids in Aqueous Media	5
Synthesis and In Vitro Antioxidant Activity of Novel Trihydroxychromen: Apigenin Derivatives	5
Zn(OAc)2•2H2O-Catalyzed Betti Base Synthesis under Solvent-free Conditions	5
Highly Efficient Visible Light Assisted Synthesis of Perimidines under Catalyst-free and Room Temperature Conditions	5
Utilizing NCP@PO(OH)2 as a Core-Shell Magnetic Nano-Catalyst for the Conversion of β-Hydroxy Nitrile to α,β-Unsaturated Carboxylic Acid	5
Synthesis of 4-hydroxyquinoline-2(1H)-ones Based on Ag(I)-catalyzed Carbon Dioxide Fixation on 2-alknylanilines	5
Weak Interactions between Epinephrine and Thymine	5
Synthesized NaA Nanozeolite as a Catalyst for the Preparation of 3-amino imidazo[1,2-a]pyridines under Solvent-Free Conditions	5
Designing, In-Silico Based Virtual Screening, Synthesis, Biological Evaluation and Molecular Dynamics Simulation of Novel Pyrazoleanalogs for the Treatment of Malaria	5
An Ultrasound-Assisted Solvent and Catalyst-Free Synthesis of Structurally Diverse Pyrazole Centered 1,5-disubstituted Tetrazoles via One-Pot Four-Component Reaction	5
β-Dihydroagarofuran-type Sesquiterpenoids from the Stems of Celastrus orbiculatus with their Cytotoxic Activities	5
Visible Light-induced Autocatalytic Aza-6π Electrocyclization to Access Polysubstituted Phenanthridines	5
Amine-Functionalized SBA-15 Mesoporous Silica-Anchored Ni Nanocatalyst for CO2 Hydrogenation Reaction	4
Investigation of Adsorption Effect of Carbon Monoxide on Coniine: A DFT Study	4
Orange Juice: A Remarkable Green Catalyst for the Michael Addition Reaction of Indoles	4
Eco-friendly, Fact and Green Synthesis of Methanobenzo[d]naphtho[1,2- g][1,3]Oxazocines using 1-Butyl-3-methylimidazolium Hydroxide under Solvent-free Ball Milling	4
A Theoretical Evaluation of the Behavior of Nitrosoamidine upon Reacting with Methoxy Butadiene as Potential Heterodiene or Heterodienophile	4
Correlations between Quantum Calculations and the Contribution of Factors Affecting the Structural Stability and Electronic Properties of Vinyl Azide and Vinyl Isocyanate	4
[Bmim][CF₃COO] as a Solvent and a Catalyst for the Knoevenagel Condensation	4
A Mild and Eco-friendly, One-pot Synthesis of 2-hydroxy-Narylacetamides from 2-chloro-N-arylacetamides	4
Efficient Synthesis of 4-Arylmethylene-3-methylisoxazol-5(4H)-one Derivatives Catalyzed by Malic Acid	4
A New Procedure for the Preparation of 3,4-dihydropyrimidin-2(1H)-one and Octahydroquinazolinone Derivatives catalyzed by SCMNPs@CA-EASO3H under Solvent-free Conditions	4
Design, Synthesis and In vitroCytotoxic Evaluation of Novel Hybrids of Artemisinin and Quinazolinone	4
Catalyst-free, One-pot Synthesis of 2-Aryl Benzimidazoles from Orthophenylenediamine and Aryl Aldehyde in Acetonitrile	4
Acemannan from Aloe vera Extract: A Catalyst-Free, Approach for the Access of Imidazole-Fused Nitrogen-Bridgehead Heterocycles	4
One-Pot Synthesis of New Highly Functionalized Pyridine-Fused Pyrazolo[1,2-b]phthalazine Derivatives	4
Synthesis and Biological Properties of D-Amino Acids	4
Coumarin-Derived Mannich Bases: A Review of Biological Activities	4
Green and Regioselective Alkylation of Dihydropyrimidinthiones through Michael Addition	4
Efficient Synthesis of the Key Intermediate of Scopolamine by [4+3] Cycloaddition Reaction	4
Chemical Constituents of the Roots of Astragalus polycladus var. nigrescens	4

Effective Synthesis of N-Alkyl-3-(Indol-3-yl)Pyrazoles from Ag₂CO₃- Catalyzed Regioselective Aza-Michael Addition of 5-(Indol-3-yl)-1HPyrazoles	4
L-Proline Nitrate: An Efficient Amino Acid Ionic Liquid Catalyzed Synthesis of 5-aryl-[1, 2, 4]-triazolidine-3-thiones	4
Synthesis of 2-Hydroxynaphthyl Pyrazolines Containing Isoniazid Moiety: A Potential Antitubercular Agent	4
Ru Nanoparticle Functionalized Silica Nanotubes as a Catalyst for CO2 Hydrogenation Reaction	3
A Review on the Syntheses and Applications of the 5H-chromeno[2,3- b]pyridines	3
WITHDRAWN: Chemical Constituents from the Root Bark of Jatropha curcas and their Cytotoxic Activities	3
Polydopamine-Modified Magnetic Nanoparticles (Fe₃O₄@PDA) for the Copper-Catalyzed Ipso-Hydroxylation of Arylboronic Acids and Subsequent O-Benzylation in Aqueous Me	3
Novel Persian Gulf Aminated Alginate Derivatives from Sargassum Bovaneum: Synthesis and Characterization	3
Chemical Constituents in the Seeds of Premna odorata	3
A Multifaceted Scaffold for Building Bioactive Compounds: Phenothiazine	3
Oxidative Cyclization of (Het)aryl-α-oxothioamides in Acidic DMSO Media: A Convenient Method for the Synthesis of 1,2,4-Thiadiazoles	3
Graphite Oxide as a Catalyst for Dehydration of Alcohols	3
Synthesis of Ferrocenylimidazo[1,2-a]pyridine-3-amines Using Catalyst ZrO(NO3)2.2H2O and their Theoretical Studies	3
Naphthol-based Optical Chemosensor for the Detection of Lead Ions in Water	3
An Efficient Propylphosphonic Anhydride (T3P®)-Mediated MW-induced Solvent-free Rapid Synthesis of Enamino Esters and Ketones including 5, 5-Dimethyl-3-aminocyclohex-2-enones	3
Base-Promoted Regioselective Bromination of Imidazo[1,2-α]pyridines with CBr4 as Bromine Source	3
Chemical Constituents and Biological Activities of Vietnamese Leea indica (Burm. f.) Merr.	3
Photochemical Synthesis of Novel Anthropinacol: Integrated DFT with ADME-Toxicological Investigations	3
Synthesis and Photophysical Properties of Benzo[c]phenanthrene Derivatives	3
How Enzyme Selectivity and Immobilization Affect Catalytic Yields in Lipase-Catalyzed Processes	3
Novel Derivatives Based on Zerumbone Scaffold as Potential Anticancer Inhibitors	3
Synthesis, Reactions and Biological Activities of Pyrimido[4,5-c] Isoquinolines (Part III)	3
DFT Study on the Interaction of Lenalidomide Anticancer Drug on the Surface of B12N12 Nanocluster	3
Solvent-free Microwave-assisted Synthesis of 1-(1,3-diphenyl-1H-pyrazol- 4-yl)-3-(2-hydroxyphenyl) Propane-1,3-dione Using K2CO3 as Green Solid Support	3
A New Arylalkanone Derived from Myristica ceylanica (Myristicaceae)	3
Visible Light Mediated, Catalyst Free, One-Pot Convenient Synthesis of Dihydropyridines	3
Investigation of the Correlation between Geometrical Relationship and the Anomeric effect on Conformational Reactivities and Analyze the 1, 4-elimination	2
Ionic Liquid: A Review on Multicomponent Synthesis of Dihydropyrano [3,2-c] Chromenes	2
The Synthesis of 2-substituted Benzo[b]furans Catalyzed by Ni/5-Bromo- 2,2’-bipyridine	2
Synthesis and Biological Evaluation of 6-Substituted Mangiferin Derivatives as Antioxidant and Anti-cancer Agents	2
An Overview: Synthesis of Menthol using Heterogeneous Catalysis	2
Synthesis of N1-caffeoyl-N10-dihydrocaffeoylspermidine (Scotanamine D)	2
Chickpea Leaf Exudates: A Highly Efficient Natural Brønsted Acidic Medium for the Synthesis of Pyran-annulated Heterocycles	2
Indole Derivatives: Versatile Scaffolds in Drug Development and Cancer Therapeutics	2
Friedel-Crafts Benzylation of Unprotected Anilines with Indole-3- carbinols to Access Trifluoro-methyl(indolyl)phenylmethanes	2
Solvent-free Simplistic Synthesis of Bis(indolyl) Methanes Using Tulsion®-8052 MP Resin	2
Electron Properties of Baicalein and its Derivatives via Quantum Chemistry Calculation: The Effect of Hydroxyl-substitution at A and C Rings	2
Catalyst-free Approach to Dihydropyrimidones Using Glycerol/Ethyl Lactate as a Recyclable and Biodegradable Promoting Medium	2
Synthesis, Spectral Characterization, Molecular Docking Studies, and Biological Evaluation of Pyranoquinolinyl Acrylic Acid (PQAA) Diastereomers as Antibacterial Agents Promoted by Indium (III) Trifla	2
Structure-based Drug Design of New Cinnamic Acid Derivatives as Tyrosinase Inhibitors	2
In-silico Identification of Dexamethasone-similar Compounds Against SARS-Cov-2 Spike Protein: A Drug Repurposing Approach	2
Synthesis, Molecular Docking Analysis and In vitro Evaluation of 1,4- Dihydroxyanthraquinone Derivatives As Anti-Trypanosomal Agents	2
A Comprehensive Review on Synthesis, Mechanisms, and Therapeutic Applications of Pyrazolidine-3,5-Dione Derivatives	2
An Improved and Practical Approach to the Synthesis of Terbinafine as an Anti-Fungal Agent	2
A Facile and Green Nitration of Easily-Hydrolyzed Aromatic Compounds Based on Direct Filtration and H2SO4 Recycling	2
In Silico Screening of Some Anti-Cancer Drugs Against the Main Protease of COVID-19 Using Molecular Docking	2
Sulfonated Ethylenediamine Functionalized Magnetic Nanoparticles as a Highly Efficient Heterogeneous Nanocatalyst for the Green Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones	2
Simple Practical Preparations of Sufentanil from Cheap and Commercially Available 1-methyl-4-piperidone	2
A Novel Enantioselective Synthesis of Cryptophycins Unit A from Rocher’s Ester	2
Study of Interactions of Nucleoside Anticancer Drugs, Capecitabine and Gemcitabine, with SWNT and BNNT using Molecular and Quantum Mechanical Calculations	2
In silico Studies of Saponins from Hoya Verticillata var. Verticillate with Important Apoptosis Potency	2
Comparative Study on the Effectiveness of Azidation Reaction for the Synthesis of Xylo-azidonucleoside Analogues by Mitsunobu and Lithium Azide Methods	2
Adsorption of Diethylstilbestrol Drug into BNNT: DFT/TD-DFT and Spectroscopic (Excited States, UV/Vis and NMR) Studies	2
The Preparation of Zr-containing Coordination Polymer as an Efficient Catalyst for Alkylation of Amines and Alcohols	2
Thymol-based Dual Chemosensor for Optical Detection of Cu²⁺ and Pb²⁺ ions and Evaluation of its Toxicity Against Plant Growth Promoting Rhizobacteria	2
Environmentally Benign Synthesis of Isoxazole–5(4H)-one Derivative Using Cashew Shell Extract as a Natural Acid Catalyst	2
Enantioselective Michael Addition of Pyrazolin-5-ones to Nitroalkenes Catalyzed by Novel Squaramide Organocatalyst	2
Synthesis and Phase Transition Behaviors of Laterally Disubstituted Liquid Crystals Containing 2,5-Dimethyl-1,4-phenylenediamines	2
Total Syntheses and Anti-inflammatory Evaluations of Karanjin and its Natural Analogues	2
N-acetylation of Aromatic Amines by One-pot Route	2
Total Synthesis of Xestodecalactone C via Sharpless Epoxidation and Friedal-Crafts Acylation	2
N-Alkylation of Amines Utilizing Magnetic Nano Chitosan Functionalized with EDTA/Co(II)	2
Prediction of Partition Coefficient of Carbamates using GA-MLR and GAANN Methods, and Comparison with Experimental Data	2
Synthesis of Polyhydroquinolines and 2-Amino-4H-Chromenes and their Alkylene Bridging Derivatives using Sulfonic acid Functionalized Heterogeneous Nanocatalyst Based on Modified Poly (Styrene-alt-Male	2
Density Functional Theory Study of Interaction between Ibuprofen and Alginic Acid for Targeted Drug Delivery	2
Mechanistic Study on Gold(I)-Catalyzed Unsaturated Spiroketalization Reaction	2
One-Pot Solvent- and Catalyst-Free Synthesis of Some New Heteroarylaminonaphthoquinones from Lawsone	2
Copper Ferrite Nanoparticles: An Efficient Catalyst for the One-Pot Four-Component Synthesis of Pyrano[2, 3-c] Pyrazole Derivatives	2
Use of 3-(Pentafluorosulfanyl)phenol to Access to Advanced Substituted Pentafluorosulfanylphenol/anisole: Application to the Synthesis of 2-(Arylpentafluorosulfanyl)indanedione	2
A Comprehensive Overview of Recent Trends in the Production of Nitrogen-Containing Heterocyclic Compounds Using Nanocatalysts	2
Folic Acid Promoted the Coupling Reaction of Epoxides and CO2	2
Synthesis Memantine and Memantine Hydrochloride by Direct Amination of 1-Bromo-3,5-dimethyladamantane with Thiourea	2
Nanostructured Iron (III)-Copper (II) Binary Oxide as a Highly Efficient Magnetically Recoverable Nanocatalyst for Facile One-pot Synthesis of 2, 4, 5-trisubstituted Imidazole and 1, 4-dihydro Pyridin	2
High-Pressure Pathway in the Two-Stage Synthesis of 5-Amino-3- Hydroxy-1-Phenyl-1H-Pyrazole	2
Recent Advances in Synthetic Strategies of Piperazine & its Analogs Via Rearrangement Reactions: A Review	2
Hydrazides and Hydrazones: Robust Scaffolds in Neurological and Neurodegenerative Disorders	2
Efficacy of Cavern Isolates for Biodegradation of Synthetic Plastic	2
A Linear and Stereoselective Approach for the Synthesis of Dapoxetine from Benzaldehyde	2
Rotational Barrier and Origin of Substituent Effect on Bond Dissociation Enthalpy of Para-substituted Anilines, Benzaldehydes, and Toluenes	2
Design and Metal-Free Synthesis and Cytotoxicity Evaluation of 5Hchromeno[ 4,3-b]pyridine Derivatives as Anti-Proliferative Agents	2