OOIR: Observatory of International Research

Papers

(The TQCC of Letters in Organic Chemistry is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Dibromination of Cinnamamides with CBr4 Under Mild Conditions	17
Phytochemical Study: Molecular Docking of Eugenol Derivatives as Antioxidant and Antimicrobial Agents	15
α,α-Dibromoketones as Synthetic Equivalents of α-Bromoketones for the Synthesis of Thiazolo[3,2-a]benzimidazoles	15
Preparation and Adsorption Properties of Polymer Particles based on N, N, N', N'-Tetrakis(4-aminophenyl)-1,4-Benzenediamine	15
Advances in the Arena of 1-(4-hydroxy-6-Methyl-2H-Pyran-2-On-3-yl)- 3-Arylpropenone: Preparation, Reactivity and Transformations	13
A Novel Study on Antioxidant Activity and Catalytic Reduction of Methylene Blue using ZnO Nanoparticles Synthesized via the Middle Part of Walnut Shell (Juglans regia) Extract	12
The Biological and Pharmacological Potentials of Indole-based Heterocycles	12
Butadiene Sulfone-catalyzed Monobromination of Arenes with NBS as the Bromination Source: A Simple, Mild, Efficient, and Chemoselective Protocol	10
On Water Synthesis of 3-Aryl-5,7-dimethyl-1,2,4-triazolo[4,3-a]pyrimidines using Iodobenzene Diacetate	10
A New Bioactive Thiazolidinone-based Azo Dye for Naked-eye Colorimetric Detection of Cyanide Ions	10
Direct Utilization of Waste Glycerol from Biodiesel Production for the Synthesis of Perimidines	9
Miscellaneous Passerini Reaction for α-Acyloxy Carboxamide: Synthesis and Process Optimization Study	9
The Nonlinear Optical Properties of Ferrocene-containing Metalloporphyrins Toward the Pico-second Laser	9
Continuous-flow Synthesis of Ruthenium Nanoparticles using a Microreactor for the Selective Hydrogenation Reaction	8
Semisynthesis and DFT Study of New Michael Adducts using (E)-α-Atlantone, Isolated from Cedrus atlantica Essential Oil	8
β-CD/Lewis Acid Dual Catalytic System for Efficient Synthesis of Pyranopyrazoles in Aqueous Environment	8
Structural Elucidation, In vitro and In silico Biological Evaluations of New Fluorinated Chalcone Derivatives for Potential Antioxidant Activity	8
An improved synthesis of Karahanaenone	8
Docking and Simulation Studies on Novel Analogues of 3,4,5-Trihydroxy Benzoic Acid as HSP90Alpha Inhibitors	8
In Silico Exploration of Flavonoids as SPPV14 Inhibitors: Potential Antiviral Agents for Sheep Pox Virus	8
Ultrasound-accelerated Synthesis of N-protected Amino Alkyl Iodides from Amino Alcohols Using P2I4 Reagent and its Application in the Synthesis of Amino Alkyl Thiols	7
Antimycobacterial Assessment and Microwave-assisted Synthesis of 2-aryl- 3-(4-methylphenylamino)thiazolidin-4-one Derivatives	7
Development of an Efficient Process for a Diagnostic Test Agent (Bentiromide) and Identification, Synthesis, Characterization, and Control Strategy for Potential Impurities	7
A Brief Review Depending on the Chemistry of Isatin in Single Pot Technique Towards the Construction of Significant and Valuable Heterocyclic Scaffolds	7
Studies Towards the Synthesis of the Pyrido[1,2-a]azepine Alkaloids	7

A Simple and Efficient Path for the Synthesis Antineoplastic Agent (2R,3R,4S,5R)-5-(6-Amino-2-Chloropurin-9-yl)-4-Fluoro-2-(Hydroxymethyl) oxolan-3-ol (Clofarabine)	7
Apigenin Bioisosteres: Synthesis and Evaluation of their Antioxidant, Antimicrobial, and Anticancer Activities	7
Synthesis of Methyl N-phenylcarbamate Derivatives by Xphos Pd G2 Catalyzed Intermolecular Amidation Reaction	6
Efficient Monoalkylation of Anilines with Chalcones using Microwave-Assisted aza-Michael Addition	6
Preface	6
Synthesis, Characterization, and Toxicity Studies of Azo Dye Ligand for Metal Assessment in Different Brands of Lipsticks in Iraq	6
Structure-Activity Design, Synthesis and Biological Activity of Newer Imidazole- Triazine Clubbed Derivatives as Antimicrobial and Antitubercular Agents	6
Ultrasound-Assisted One-Pot Synthesis of Tetrahydropyrimidne Derivatives through Biginelli Condensation: A Catalyst Free Green Chemistry Approach	6
A Green and Convenient Approach for the Synthesis of Indole-acrylonitrile and Indole-coumarin Hybrids in Aqueous Media	5
A Novel Powerful γ-Fe2O3 @ CPTMS - Diethylene Triamine (DETA) @SO3H as a Heterogeneous Nanocatalyst, Recyclable and Efficient via Microwave-assisted for the Synthesis of Benzoxazinone- 4(3H)-one Deriv	5
An Efficient Rapid Synthesis of Benzoxazoles and Benzothiazoles Using PMA.SiO2 at Room Temperature under Heterogeneous Conditions	5
Insights Into the Synthetic Strategies, Biological Activity, and Structure- Activity Relationship of Pyridine and Analogs: A Review	5
Synthesis of 4-hydroxyquinoline-2(1H)-ones Based on Ag(I)-catalyzed Carbon Dioxide Fixation on 2-alknylanilines	5
Novel Mannich Base Derivatives: Synthesis, Characterization, Antimicrobial and Antioxidant Activities	5
Utilizing NCP@PO(OH)2 as a Core-Shell Magnetic Nano-Catalyst for the Conversion of β-Hydroxy Nitrile to α,β-Unsaturated Carboxylic Acid	5
Solid State Kinetics and Antimicrobial Studies for Copper (II) Sesame and Copper (II) Groundnut Complexes with Substituted Benzothiazole Ligand	5
Facile Synthesis of Substituted Trifluoromethyl Piperidines with Diversifying Functionalization	5
An Ultrasound-Assisted Solvent and Catalyst-Free Synthesis of Structurally Diverse Pyrazole Centered 1,5-disubstituted Tetrazoles via One-Pot Four-Component Reaction	5
A Review on Diverse Biological Activity of Heterocyclic Nucleus Pyrazine and its Derivatives: A Key for the Researchers	5
β-Dihydroagarofuran-type Sesquiterpenoids from the Stems of Celastrus orbiculatus with their Cytotoxic Activities	5
Acknowledgements to Reviewers	4
Weak Interactions between Epinephrine and Thymine	4
Oxidative Coupling: An Important Tool for Pyrrole Synthesis	4
Efficient Synthesis of 4-Arylmethylene-3-methylisoxazol-5(4H)-one Derivatives Catalyzed by Malic Acid	4
A New Procedure for the Preparation of 3,4-dihydropyrimidin-2(1H)-one and Octahydroquinazolinone Derivatives catalyzed by SCMNPs@CA-EASO3H under Solvent-free Conditions	4
Amine-Functionalized SBA-15 Mesoporous Silica-Anchored Ni Nanocatalyst for CO2 Hydrogenation Reaction	4
Synthesized NaA Nanozeolite as a Catalyst for the Preparation of 3-amino imidazo[1,2-a]pyridines under Solvent-Free Conditions	4
The Miraculous of Rhizopus arrhizus in the Structural Modifications of Steroidal Skeleton	4
Design, Synthesis and Acetylcholinesterase and Butylcholinesterase Inhibition Activity of Novel 1-(Alkyl)-3-(2-oxo-2H-chromenyloxy Acetamido) methylpyridinium Salts	4
A Mild and Eco-friendly, One-pot Synthesis of 2-hydroxy-Narylacetamides from 2-chloro-N-arylacetamides	4
Design, Synthesis and In vitroCytotoxic Evaluation of Novel Hybrids of Artemisinin and Quinazolinone	4
Green and Regioselective Alkylation of Dihydropyrimidinthiones through Michael Addition	4
Ionic liquid Supported Quinuclidine Catalyzed Morita-Baylis-Hillman Reaction	4
Zn(OAc)2•2H2O-Catalyzed Betti Base Synthesis under Solvent-free Conditions	4
Highly Efficient Visible Light Assisted Synthesis of Perimidines under Catalyst-free and Room Temperature Conditions	4
Efficient Synthesis of the Key Intermediate of Scopolamine by [4+3] Cycloaddition Reaction	4
Investigation of Adsorption Effect of Carbon Monoxide on Coniine: A DFT Study	4
Coumarin-Derived Mannich Bases: A Review of Biological Activities	4
Graphite Oxide as a Catalyst for Dehydration of Alcohols	3
Acemannan from Aloe vera Extract: A Catalyst-Free, Approach for the Access of Imidazole-Fused Nitrogen-Bridgehead Heterocycles	3
Polydopamine-Modified Magnetic Nanoparticles (Fe₃O₄@PDA) for the Copper-Catalyzed Ipso-Hydroxylation of Arylboronic Acids and Subsequent O-Benzylation in Aqueous Me	3
Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanidebased Three-component Reaction	3
Synthesis of 2-Hydroxynaphthyl Pyrazolines Containing Isoniazid Moiety: A Potential Antitubercular Agent	3
Eco-friendly, Fact and Green Synthesis of Methanobenzo[d]naphtho[1,2- g][1,3]Oxazocines using 1-Butyl-3-methylimidazolium Hydroxide under Solvent-free Ball Milling	3
Synthesis and Biological Properties of D-Amino Acids	3
Ru Nanoparticle Functionalized Silica Nanotubes as a Catalyst for CO2 Hydrogenation Reaction	3
Synthetic Investigations on Medicinally Important Quinoxaline Scaffold: A Mini Review	3
A Review on the Syntheses and Applications of the 5H-chromeno[2,3- b]pyridines	3
An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst	3
[Bmim][CF₃COO] as a Solvent and a Catalyst for the Knoevenagel Condensation	3

L-Proline Nitrate: An Efficient Amino Acid Ionic Liquid Catalyzed Synthesis of 5-aryl-[1, 2, 4]-triazolidine-3-thiones	3
Orange Juice: A Remarkable Green Catalyst for the Michael Addition Reaction of Indoles	3
Catalyst-free, One-pot Synthesis of 2-Aryl Benzimidazoles from Orthophenylenediamine and Aryl Aldehyde in Acetonitrile	3
How Enzyme Selectivity and Immobilization Affect Catalytic Yields in Lipase-Catalyzed Processes	3
Synthesis of Ferrocenylimidazo[1,2-a]pyridine-3-amines Using Catalyst ZrO(NO3)2.2H2O and their Theoretical Studies	3
Correlations between Quantum Calculations and the Contribution of Factors Affecting the Structural Stability and Electronic Properties of Vinyl Azide and Vinyl Isocyanate	3
WITHDRAWN: Chemical Constituents from the Root Bark of Jatropha curcas and their Cytotoxic Activities	3
New Strategy for Synthesis of Anticancer Active Piperastrol, Enastron Using Ammonium Sulfocyanate	3
Synthesis of Novel N-(R)-2-(1-Adamantyl)-1H-Benzimidazole-5(6)- Carboxamide, Carbohydrazide and 1,3,4-Oxadiazole Derivatives	3
Effective Synthesis of N-Alkyl-3-(Indol-3-yl)Pyrazoles from Ag₂CO₃- Catalyzed Regioselective Aza-Michael Addition of 5-(Indol-3-yl)-1HPyrazoles	3
Ring Opening of 1,1’-Sulfonyl Bis-Aziridines Derived from L-Amino Acids and DFT Study of the Affinity Toward Different Nucleophiles	3
Synthesis and Antimicrobial Evaluation of Quinazoline-4[3H]-one Derivatives	3
Therapeutic Effect, Chemical Composition, Ethnobotanical Profile of Eucalyptus globulus: A Review	3
Chemical Constituents of the Roots of Astragalus polycladus var. nigrescens	3
DFT Study on the Interaction of Lenalidomide Anticancer Drug on the Surface of B12N12 Nanocluster	3
Novel Derivatives Based on Zerumbone Scaffold as Potential Anticancer Inhibitors	3
A Theoretical Evaluation of the Behavior of Nitrosoamidine upon Reacting with Methoxy Butadiene as Potential Heterodiene or Heterodienophile	3
Visible Light Mediated, Catalyst Free, One-Pot Convenient Synthesis of Dihydropyridines	2
Chemical Constituents in the Seeds of Premna odorata	2
Nanostructured Iron (III)-Copper (II) Binary Oxide as a Highly Efficient Magnetically Recoverable Nanocatalyst for Facile One-pot Synthesis of 2, 4, 5-trisubstituted Imidazole and 1, 4-dihydro Pyridin	2
Synthesis Memantine and Memantine Hydrochloride by Direct Amination of 1-Bromo-3,5-dimethyladamantane with Thiourea	2
Study of Interactions of Nucleoside Anticancer Drugs, Capecitabine and Gemcitabine, with SWNT and BNNT using Molecular and Quantum Mechanical Calculations	2
Catalyst-free Approach to Dihydropyrimidones Using Glycerol/Ethyl Lactate as a Recyclable and Biodegradable Promoting Medium	2
A New Arylalkanone Derived from Myristica ceylanica (Myristicaceae)	2
Recent Advances in Synthetic Strategies of Piperazine & its Analogs Via Rearrangement Reactions: A Review	2
Mechanistic Study on Gold(I)-Catalyzed Unsaturated Spiroketalization Reaction	2
Electron Properties of Baicalein and its Derivatives via Quantum Chemistry Calculation: The Effect of Hydroxyl-substitution at A and C Rings	2
A Comprehensive Overview of Recent Trends in the Production of Nitrogen-Containing Heterocyclic Compounds Using Nanocatalysts	2
Pd/C Catalyzed Decarboxylation-Transfer Hydrogenation of Quinoline Carboxylic Acids	2
Solvent-free Microwave-assisted Synthesis of 1-(1,3-diphenyl-1H-pyrazol- 4-yl)-3-(2-hydroxyphenyl) Propane-1,3-dione Using K2CO3 as Green Solid Support	2
Total Synthesis of Xestodecalactone C via Sharpless Epoxidation and Friedal-Crafts Acylation	2
Molecular Docking, Topological Analysis and Vibrational Studies on N-(2-Bromoethyl) Succinimide: Antidepressant Agent	2
Synthesis, Molecular Docking Analysis and In vitro Evaluation of 1,4- Dihydroxyanthraquinone Derivatives As Anti-Trypanosomal Agents	2
Base-Promoted Regioselective Bromination of Imidazo[1,2-α]pyridines with CBr4 as Bromine Source	2
Synthesis and Photophysical Properties of Benzo[c]phenanthrene Derivatives	2
Synthesis and Biological Evaluation of 6-Substituted Mangiferin Derivatives as Antioxidant and Anti-cancer Agents	2
Indole Derivatives: Versatile Scaffolds in Drug Development and Cancer Therapeutics	2
An Overview: Synthesis of Menthol using Heterogeneous Catalysis	2
One-Pot Solvent- and Catalyst-Free Synthesis of Some New Heteroarylaminonaphthoquinones from Lawsone	2
Chemical Constituents and Biological Activities of Vietnamese Leea indica (Burm. f.) Merr.	2
Chickpea Leaf Exudates: A Highly Efficient Natural Brønsted Acidic Medium for the Synthesis of Pyran-annulated Heterocycles	2
Sulfonated Ethylenediamine Functionalized Magnetic Nanoparticles as a Highly Efficient Heterogeneous Nanocatalyst for the Green Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones	2
Cytotoxic and Pro-Apoptotic Activities of Diterpenoids from Zhumeria Majdae	2
An Efficient Propylphosphonic Anhydride (T3P®)-Mediated MW-induced Solvent-free Rapid Synthesis of Enamino Esters and Ketones including 5, 5-Dimethyl-3-aminocyclohex-2-enones	2
Prediction of Partition Coefficient of Carbamates using GA-MLR and GAANN Methods, and Comparison with Experimental Data	2
A Multifaceted Scaffold for Building Bioactive Compounds: Phenothiazine	2
Efficacy of Cavern Isolates for Biodegradation of Synthetic Plastic	2
Two Schiff-base Complexes of Copper and Zirconium Oxide Fabricated on Magnetic Nanoparticles as Practical and Recyclable Catalysts in C-C Coupling Reaction	2
Solvent-free, Silica Catalyzed Intriguing Conversion of 3- Hydrazonobutan-2-one Oxime into Biacetyl Bis-hydrazone Schiff Bases	2
Structure-based Drug Design of New Cinnamic Acid Derivatives as Tyrosinase Inhibitors	2
Enantioselective Michael Addition of Pyrazolin-5-ones to Nitroalkenes Catalyzed by Novel Squaramide Organocatalyst	2
Comparative Study on the Effectiveness of Azidation Reaction for the Synthesis of Xylo-azidonucleoside Analogues by Mitsunobu and Lithium Azide Methods	2
Ionic Liquid: A Review on Multicomponent Synthesis of Dihydropyrano [3,2-c] Chromenes	2
High-Pressure Pathway in the Two-Stage Synthesis of 5-Amino-3- Hydroxy-1-Phenyl-1H-Pyrazole	2
Synthesis, Spectral Characterization, Molecular Docking Studies, and Biological Evaluation of Pyranoquinolinyl Acrylic Acid (PQAA) Diastereomers as Antibacterial Agents Promoted by Indium (III) Trifla	2
Thymol-based Dual Chemosensor for Optical Detection of Cu²⁺ and Pb²⁺ ions and Evaluation of its Toxicity Against Plant Growth Promoting Rhizobacteria	2
Density Functional Theory Study of Interaction between Ibuprofen and Alginic Acid for Targeted Drug Delivery	2
Synthesis of N1-caffeoyl-N10-dihydrocaffeoylspermidine (Scotanamine D)	2
Adsorption of Diethylstilbestrol Drug into BNNT: DFT/TD-DFT and Spectroscopic (Excited States, UV/Vis and NMR) Studies	2
Solvent-free Simplistic Synthesis of Bis(indolyl) Methanes Using Tulsion®-8052 MP Resin	2
Investigation of the Correlation between Geometrical Relationship and the Anomeric effect on Conformational Reactivities and Analyze the 1, 4-elimination	2
Novel Persian Gulf Aminated Alginate Derivatives from Sargassum Bovaneum: Synthesis and Characterization	2
Total Syntheses and Anti-inflammatory Evaluations of Karanjin and its Natural Analogues	2