OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Peptide Research and Therapeutics is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Role of Polypeptide Inflammatory Biomarkers in the Diagnosis and Monitoring of COVID-19	81
ACE2 Peptide Fragment Interaction with Different S1 Protein Sites	70
Synthetic Antimicrobial Peptide Polybia MP-1 (Mastoparan) Inhibits Growth of Antibiotic Resistant Pseudomonas aeruginosa Isolates From Mastitic Cow Milk	55
In-Silico Validation of Prosopis ciniraria Therapeutic Peptides Against Fungal Cell Wall: Better Treatment Strategy for Fungal Diseases	47
Glutathione Encapsulation in Core-Shell Drug Nanocarriers (Polymersomes and Niosomes) Prevents Advanced Glycation End-products Toxicities	39
Stability of Oligopeptides in Solution. Proteolytic Digestion and Potential Dimerization Process	37
Evaluation of Functional Properties of Wheat Germ Protein Hydrolysates and Its Effect on Physicochemical Properties of Frozen Yogurt	30
Immunoinformatics Insights into the Internalin A and B Proteins to Design a Multi-Epitope Subunit Vaccine for L. monocytogenes	25
Pierce into Structural Changes of Interactions Between Mutated Spike Glycoproteins and ACE2 to Evaluate Its Potential Biological and Therapeutic Consequences	24
Recombinant Expression and Antibacterial Properties of BmTXKS2 Venom Peptide in Fusion with GST	21
Structural Characteristics, Prokaryotic Expression and Activity Analysis of Antimicrobial Peptide ALFPm10 from Penaeus monodon	18
Pulse Derived Bioactive Peptides as Novel Nutraceuticals: A Review	18
Design and In Silico Evaluation of a Novel Cyclic Disulfide-Rich anti-VEGF Peptide as a Potential Antiangiogenic Drug	17
l-asparaginase: Need for an Expedition from an Enzymatic Molecule to Antimicrobial Drug	16
In-Silico Design of a Novel Tridecapeptide Targeting Spike Protein of SARS-CoV-2 Variants of Concern	16
The Stability of Food Bioactive Peptides in Blood: An Overview	15
Preliminary Study on the Antibacterial and Cytotoxic Effects of the Synthetic New Peptide NJP9-A	15
Immuno-Affinity Study of Oxidative Tyrosine Containing Peptides	15
Therapeutic Potential of Antimicrobial Peptides for Wound Healing	15
Correction to: Investigation of Fluorine-18 Labelled Peptides for Binding to Cholecystokinin-2 Receptors with High Affinity	15
Peripheral Administration of an Opioid Peptide Analog Ameliorates Morphine-Produced Hyperalgesia in a Spared Nerve Injury Model	15
Production of Soluble Bioactive NmDef02 Plant Defensin in Escherichia coli	14
Evaluation the Therapeutic Index of Recombinant Antimicrobial S3 Tetramer-Peptides Expressed in E. coli	13
Involvement of Cathepsins Protein in Mycobacterial Infection and Its Future Prospect as a Therapeutic Target	13
Molecular Characterization and Designing of a Novel Multiepitope Vaccine Construct Against Pseudomonas aeruginosa	13

In silico Design and Characterization of Multi-epitopes Vaccine for SARS-CoV2 from Its Spike Protein	13
Chikungunya Virus Vaccine Development: Through Computational Proteome Exploration for Finding of HLA and cTAP Binding Novel Epitopes as Vaccine Candidates	13
Potential Efficacy of Biofilm-Forming Biosurfactant Bacillus firmus HussainT-Lab.66 Against Rhizoctonia solani and Mass Spectrometry Analysis of its Metabolites	12
Bioactivities of In Vitro Transepithelial Transported Peptides from Cooked Chicken Breast	12
In Silico Analysis of Potential Outer Membrane Beta-Barrel Proteins in Aeromonas hydrophila Pangenome	12
Environmentally Conscious In-Water Peptide Synthesis Using Boc Strategy	12
Design of Monovalent and Chimeric Tetravalent Dengue Vaccine Using an Immunoinformatics Approach	12
In-Silico Vaccine Design Based on a Novel Vaccine Candidate Against Infections Caused by Acinetobacter baumannii	11
Evaluation of Cell-Penetrating Peptides as Mucosal Immune Enhancers for Nasal Vaccination	11
A Comprehensive in Silico Analysis for Identification of Immunotherapeutic Epitopes of HPV-18	11
Expression and Characterization of a Potent Long-Acting GLP-1 Receptor Like Agonist, Exendin-4-Fc	11
Quest for Novel Preventive and Therapeutic Options Against Multidrug-Resistant Pseudomonas aeruginosa	11
A Mini-Review on Potential of Neuropeptides as Future Therapeutics	11
Detecting the Dominant T and B Epitopes of Klebsiella pneumoniae Ferric Enterobactin Protein (FepA) and Introducing a Single Epitopic Peptide as Vaccine Candidate	11
Computational Design and Analysis of a Multi-epitope Against Influenza A virus	10
Antibacterial Activity of RM12, a Tachykinin Derivative, Against Pseudomonas aeruginosa	10
Development of ULYSSIS, a Tool for the Biosynthesis of Cyclotides and Cyclic Knottins	10
Correction to: Galanin Peptides Alleviate Myocardial Ischemia/Reperfusion Injury by Reducing Reactive Oxygen Species Formation	10
Cyclic Dodecapeptide Induces Cell Death Through Membrane–Peptide Interactions in Breast Cancer Cells	10
Immunoinformatics Approach to Design a Novel Subunit Vaccine Against Visceral Leishmaniasis	10
Novel Antiproliferative Tripeptides Inhibit AP-1 Transcriptional Complex	9
New Computational Approach for Peptide Vaccine Design Against SARS-COV-2	9
Linear and Branched Forms of Short Antimicrobial Peptide-IRK Inhibit Growth of Multi Drug Resistant Staphylococcus aureus Isolates from Mastitic Cow Milk	9
PeptCreatR: A Web App for Unique Peptides in Human	8
Wasp Venom Peptide (Polybia MP-1) Shows Antimicrobial Activity Against Multi Drug Resistant Bacteria Isolated from Mastitic Cow Milk	7
Peptide Affinity Chromatography Applied to Therapeutic Antibodies Purification	7
Hydrophobic Residues Confer the Helicity and Membrane Permeability of Ocellatin-1 Antimicrobial Peptide Scaffold Towards Therapeutics	7
Viral 3CLpro as a Target for Antiviral Intervention Using Milk-Derived Bioactive Peptides	7
Breast Tumor Targeting in Mice Bearing 4T1 Tumor with Labeled CXCR4 Antagonist Analogue	7
Identifying Dipeptidyl Peptidase-IV Inhibitory Peptides Based on Correlation Information of Physicochemical Properties	7
Head and Neck Squamous Cell Carcinoma: Risk Factors, Molecular Alterations, Immunology and Peptide Vaccines	7
Deciphering the Limitations and Antibacterial Mechanism of Cruzioseptins	7
Lactic Acid Bacteria Bacteriocin, an Antimicrobial Peptide Effective Against Multidrug Resistance: a Comprehensive Review	7
Mycobacterium tuberculosis Rv0292 Protein Peptides Could be Included in a Synthetic Anti-tuberculosis Vaccine	6
In Silico Analysis of Inhibiting Papain-like Protease from SARS-CoV-2 by Using Plant-Derived Peptides	6
Enhanced Activation of Atrial Natriuretic Peptide (ANP) and Natriuretic Peptide Receptor-A (NPRA) in Chronic Cigarette Smoke-Induced Lung Inflammation in Experimental Rats	6
Total Synthesis of Novel Antimicrobial β-Hairpin Capitellacin Via Rapid Flow-Based SPPS Assembly and Regioselective On-Resin Disulfide Cyclisation	6
Enhanced Production of Iturin A-2 Generated from Bacillus velezensis T701 and the Antitumor Activity of Iturin A-2 against Human Gastric Carcinoma Cells	6
Phα1β is a Promising Neuroprotective Peptide from the Phoneutria nigriventer ‘Armed’ Spider	6
HL-7 and HL-10 Peptides Stimulate Insulin Secretion in the INS-1 Insulinoma Cell Line through Incretin-Dependent Pathway and Increasing the Glucose Uptake in L6 Myoblast	6
Crab Pentapeptide and Its Anti-inflammatory Activity on Macrophage Cells	5
Subtractive Proteomics and Immuno-informatics Approaches for Multi-peptide Vaccine Prediction Against Klebsiella oxytoca and Validation Through In Silico Expression	5
The Interaction of Possible Anti-AD ASA-NAP Peptide Conjugate with Tubulin: A Theoretical and Experimental Insight	5
VirVACPRED: A Web Server for Prediction of Protective Viral Antigens	5
Prophylactic Application of MA-[d-Leu-4]-OB3, a Small Molecule Synthetic Peptide Leptin Mimetic, Prevents or Slows the Progression of Obesity, Insulin Resistance, and Cognitive Impairment in a Mouse M	4
Biofilm Effects of the Soil Bacillus cereus Metabolites: Isolation, Characterization and Antimicrobial Activity Against Methicillin-Resistant Staphylococcus aureus	4
Exploring Structural Mechanism of COVID-19 Treatment with Glutathione as a Potential Peptide Inhibitor to the Main Protease: Molecular Dynamics Simulation and MM/PBSA Free Energy Calculations Study	4
A Novel Multiepitope Vaccine Against Bladder Cancer Based on CTL and HTL Epitopes for Induction of Strong Immune Using Immunoinformatics Approaches	4
Nano Defensin: A Promising Antibacterial Agent Against Colorectal Cancer Related Bacteria	4
Immunoinformatics Construction of B Cell Epitope-Based Hypoallergenic Der f 34 Vaccine for Immunotherapy of House Dust Mite Allergy	4

A Comprehensive Review on the Anticancer Potential of Bacteriocin: Preclinical and Clinical Studies	4
Production and Evaluation of In-vitro and In-vivo Effects of P28-IL24, a Promising Anti-breast Cancer Fusion Protein	4
Extracellular Calcium Contributes to Orexin-Induced Postsynaptic Excitation of the Rat Locus Coeruleus Neurons	4
In Vitro and In Vivo Investigation of the Radiation-Sensitizing Effects of Melittin in Breast Cancer Cells	4
Integrated Multi-omics, Virtual Screening and Molecular Docking Analysis of Methicillin-Resistant Staphylococcus aureus USA300 for the Identification of Potential Therapeutic Targets: An In-Silico App	4