Purinergic Signalling

Papers
(The TQCC of Purinergic Signalling is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)
ArticleCitations
Some reflections after a long life in science43
Hippocampal astrocytes relieve anxiogenic behavior by increasing, via the release of ATP, excitatory synaptic transmission in dentate gyrus granule cells38
Electroacupuncture may alleviate diabetic neuropathic pain by inhibiting the microglia P2X4R and neuroinflammation36
Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5′-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives30
Role of the P2X7 receptor in breast cancer progression29
Characterization of purinergic signaling in tumor-infiltrating lymphocytes from lower- and high-grade gliomas29
Purinergic P2X7 receptor involves in anti-retinal photodamage effects of berberine25
The impact of inosine on hippocampal synaptic transmission and plasticity involves the release of adenosine through equilibrative nucleoside transporters rather than the direct activation of adenosine24
Neuroprotection of exercise: P2X4R and P2X7R regulate BDNF actions21
P2Y12 receptor antagonism inhibits proliferation, migration and leads to autophagy of glioblastoma cells21
The exploration of active components of 701 Dieda Zhentong patch and analgesic properties on chronic constriction injury rats19
UTP is a regulator of in vitro and in vivo angiogenic properties of cardiac adipose–derived stem cells19
Promoting glymphatic flow: A non-invasive strategy using 40 Hz light flickering19
Moxibustion pre-treatment attenuates seizure severity during status epilepticus and counteracts the proconvulsant function of the purinergic P2X7 receptor19
Human plasmacytoid dendritic cells express the functional purinergic halo (CD39/CD73)18
Electroacupuncture may alleviate inflammatory pain by downregulating the expression of P2Y14 receptor in the primary somatosensory cortex16
P2X7 receptor promotes migration and invasion of non-small cell lung cancer A549 cells through the PI3K/Akt pathways16
Purinergic receptors mediate endothelial dysfunction and participate in atherosclerosis16
Correction to: A1R–A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes16
Diadenosine pentaphosphate regulates dendrite growth and number in cultured hippocampal neurons15
Effects of nanoflubendazole and purinergic signaling modulation in overcoming neuroblastoma chemoresistance15
ENTPD1 (CD39) and NT5E (CD73) expression in human medulloblastoma: an in silico analysis14
Pharmacological interaction and immune response of purinergic receptors in therapeutic modulation14
Purinergic P2X3 receptors in the carotid body as new therapeutic targets for controlling heart failure13
Macrophage P2Y6 receptor signalling as a key mediator and therapeutic target in atherosclerosis13
Inhibiting the P2Y13 receptor reduces IL-33 and HMGB1 lung concentrations and inflammatory cell infiltration in a murine model of asthma13
Astrocytic adenosine A2B receptors: a crucial player in brain function13
Editorial: purinergic signalling—perspectives from Australia and New Zealand13
Mono-ADP-ribosylation sites of human CD73 inhibit its adenosine-generating enzymatic activity12
Pharmacological characterization of P2Y receptor subtypes – an update12
Pleiotropic effects of clopidogrel12
The P2Y2 receptor as a sensor of nucleotides and cell recruitment during inflammatory processes of the liver12
Second meeting of the Australian and New Zealand Purine Club12
Purines help determine the gut’s sweet tooth12
Synthesis of new non-natural l-glycosidic flavonoid derivatives and their evaluation as inhibitors of Trypanosoma cruzi ecto-nucleoside triphosphate diphosphohydrolase 1 (TcNTPDase1)11
May be adenosine an immuno-quorum-sensing signal?11
Purinergic ATP triggers moxibustion-induced local anti-nociceptive effect on inflammatory pain model11
MicroRNA: Crucial modulator in purinergic signalling involved diseases11
Preface to special issue “A tribute to Maria Teresa Miras-Portugal”11
Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonists10
P2 purinergic receptor dysregulation in urologic disease10
NPP1 and TNAP hydrolyze ATP synergistically during biomineralization10
RETRACTED ARTICLE: Lysophosphatidylcholine induces adenosine release from macrophages via TRPM7-mediated mitochondrial activation10
Purinergic system in cancer stem cells10
Genetic polymorphisms of purinergic P2Y2 receptor were associated with the susceptibility to essential hypertension in Chinese postmenopausal women10
Cutaneous melanoma and purinergic modulation by phenolic compounds9
Mechanisms of ATP release in pain: role of pannexin and connexin channels9
P2Y11/IL-1 receptor crosstalk controls macrophage inflammation: a novel target for anti-inflammatory strategies?9
The anti-inflammatory effect of physical exercise on type 2 diabetes: the role of purinergic signaling9
P2Y6 promoted pruning of FSTL1 nerves by cutaneous macrophages to reset pain threshold and cardiac function9
Anti-inflammatory and analgesic properties of Polyphyllin VI revealed by network pharmacology and RNA sequencing8
Crosstalk between P2Y receptors and cyclooxygenase activity in inflammation and tissue repair8
Ginsenosides enhance P2X7-dependent cytokine secretion from LPS-primed rodent macrophages8
DUSP1/MKP-1 represents another piece in the P2X7R intracellular signaling puzzle in cerebellar cells: our last journey with Mª Teresa along the purinergic pathways of Eden8
The role of Pannexin-1 channels and extracellular ATP in the pathogenesis of the human immunodeficiency virus8
Adenosine receptor signalling in Alzheimer’s disease8
Pannexin 3 channels in health and disease8
Partners in health and disease: pineal gland and purinergic signalling7
Editorial—Translation of purinergic drugs into therapeutic use7
Identification of novel proteins involved in P2X7-mediated signaling cascades7
Fluorescent A2A and A3 adenosine receptor antagonists as flow cytometry probes7
P2Y11 receptor is a critical regulator of extracellular ATP-mediated premature senescence in lung fibroblasts: Implications of ER-Ca+2 release/mitochondrial ROS production signaling pathway7
Potential role of the P2X7 receptor in the proliferation of human diffused large B-cell lymphoma7
Heterologous expression and biochemical characterization of the recombinant nucleoside triphosphate diphosphohydrolase 2 (LbNTPDase2) from Leishmania (Viannia) braziliensis7
Analgesic effect of electroacupuncture on bone cancer pain in rat model: the role of peripheral P2X3 receptor7
Quinacrine is not a vital fluorescent probe for vesicular ATP storage6
P2 purinergic receptor expression and function in tumor-related immune cells6
Pro- and anti-inflammatory macrophages express a sub-type specific purinergic receptor profile6
T cell-derived adenosine regulates fibroblast IL-6 formation via A2B receptors in the infarcted heart6
Antagonism of the ATP-gated P2X7 receptor inhibits the proliferation of hepatocellular carcinoma cells6
Retraction Note: Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells6
Purinergic P2Y1 and P2Y12 receptors control enteric nervous system activity through neuro-glia-macrophage crosstalk6
Role and recent progress of P2Y12 receptor in cancer development6
In vivo phenotypic validation of adenosine receptor-dependent activity of non-adenosine drugs6
Correction to: Purinoceptor: a novel target for hypertension5
Mechanosensitive release of ATP in the urinary bladder mucosa5
The P2Y2 receptor: a new player in taste buds5
Transactivation of receptor tyrosine kinases by purinergic P2Y and adenosine receptors5
CD39 in the development and progression of pulmonary arterial hypertension5
Purinergic signaling in liver disease: calcium signaling and induction of inflammation5
Announcement of changes to the Editorial Board5
The enzymatic degradation of ATP to adenosine by microglial CD39 regulates neurovascular coupling and metabolic supply to the brain5
Molecular mechanisms of extracellular-ATP-mediated colorectal cancer progression: Implication of purinergic receptors-mediated nucleocytoplasmic shuttling of HuR5
Ectonucleotidases as bridge between the ATP and adenosine world: reflections on Geoffrey Burnstock5
Gallic acid modulates purine metabolism and oxidative stress induced by ethanol exposure in zebrafish brain5
Purinergic signaling as a new mechanism underlying physical exercise benefits: a narrative review5
EU COST Action CA21130 PRESTO ‘P2X receptors as therapeutic targets’ inaugural meeting report5
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