OOIR: Observatory of International Research

Papers

(The TQCC of Cancer Biomarkers is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Prognostic value of the systemic inflammation response index (SIRI) before and after surgery in operable breast cancer patients	34
MiR-101 reduces cell proliferation and invasion and enhances apoptosis in endometrial cancer via regulating PI3K/Akt/mTOR	34
MicroRNA profiling in serum: Potential signatures for breast cancer diagnosis	33
Predicting pancreatic ductal adenocarcinoma using artificial intelligence analysis of pre-diagnostic computed tomography images	33
CircRNA_100565 contributes to cisplatin resistance of NSCLC cells by regulating proliferation, apoptosis and autophagy via miR-337-3p/ADAM28 axis	31
LncRNA-SARCC sensitizes osteosarcoma to cisplatin through the miR-143-mediated glycolysis inhibition by targeting Hexokinase 2	30
Circ_0000376 enhances the proliferation, metastasis, and chemoresistance of NSCLC cells via repressing miR-384	25
LncRNA HOTAIR promotes breast cancer progression through regulating the miR-129-5p/FZD7 axis	24
MicroRNA-134 inhibits tumor stem cell migration and invasion in oral squamous cell carcinomas via downregulation of PI3K-Akt signaling pathway by inhibiting LAMC2 expression	23
Circ_0007031 enhances tumor progression and promotes 5-fluorouracil resistance in colorectal cancer through regulating miR-133b/ABCC5 axis	23
MiR-200c-3p suppression is associated with development of acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer via a medi	22
miR-21-5p promotes lung adenocarcinoma cell proliferation, migration and invasion via targeting WWC2	22
LncRNA-SNHG7 interferes with miR-34a to de-sensitize gastric cancer cells to cisplatin	21
RUNX2 promotes malignant progression in gastric cancer by regulating COL1A1	21
LncRNA XIST/miR-137 axis strengthens chemo-resistance and glycolysis of colorectal cancer cells by hindering transformation from PKM2 to PKM1	21
Silencing circPVT1 enhances radiosensitivity in non-small cell lung cancer by sponging microRNA-1208	19
Expression pattern and prognostic significance of CDKs in breast cancer: An integrated bioinformatic study	19
A five-gene signature derived from m6A regulators to improve prognosis prediction of neuroblastoma	18
LncRNA SNHG8 induces ovarian carcinoma cells cellular process and stemness through Wnt/β-catenin pathway	17
LncRNA SNHG17 promotes the progression of oral squamous cell carcinoma by modulating miR-375/PAX6 axis	17
Modeling the time-related fluctuations of AFP and PIVKA-II serum levels in patients with cirrhosis undergoing surveillance for hepatocellular carcinoma	16
Bone mesenchymal stem cells derived extracellular vesicles promote TRAIL-related apoptosis of hepatocellular carcinoma cells via the delivery of microRNA-20a-3p	16
MiR-204-5p/TFAP2A feedback loop positively regulates the proliferation, migration, invasion and EMT process in cervical cancer	16
Identification of MYLIP gene and miRNA-802 involved in the growth and metastasis of cervical cancer cells	16
Four genes relevant to pathological grade and prognosis in ovarian cancer	16

Circular RNA circ_0000337 contributes to osteosarcoma via the miR-4458/BACH1 pathway	16
Prognostic significance of elevated pretreatment serum levels of CEA and CA-125 in epithelial ovarian cancer	16
LncRNA testis-specific transcript, Y-linked 15 (TTTY15) promotes proliferation, migration and invasion of colorectal cancer cells via regulating miR-29a-3p/DVL3 axis	16
LINC00467 knockdown repressed cell proliferation but stimulated cell apoptosis in glioblastoma via miR-339-3p/IP6K2 axis	16
TRIB3 promotes hepatocellular carcinoma growth and predicts poor prognosis	15
Overexpression of HSP10 correlates with HSP60 and Mcl-1 levels and predicts poor prognosis in non-small cell lung cancer patients	15
Exosomal microRNAs as potential biomarkers for osimertinib resistance of non-small cell lung cancer patients	15
Exosome-delivered circular RNA DLGAP4 induces chemoresistance via miR-143-HK2 axis in neuroblastoma	15
SPARC regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma	14
Upregulation lnc-NEAT1 contributes to colorectal cancer progression through sponging miR-486-5p and activating NR4A1/Wnt/β-catenin pathway	14
LINC00893 inhibits papillary thyroid cancer by suppressing AKT pathway via stabilizing PTEN	14
PDGF-BB induces conversion, proliferation, migration, and collagen synthesis of oral mucosal fibroblasts through PDGFR-β/PI3K/ AKT signaling pathway	14
ZMYND8 expression combined with pN and pM classification as a novel prognostic prediction model for colorectal cancer: Based on TCGA and GEO database analysis	14
Alterations of regulatory factors and DNA methylation pattern in thyroid cancer	13
Plasma exosome-derived microRNA-532 as a novel predictor for acute myeloid leukemia	13
FOXD1, negatively regulated by miR-186, promotes the proliferation, metastasis and radioresistance of nasopharyngeal carcinoma cells	13
Anti-cervical cancer activity of secondary metabolites of endophytic fungi from Ginkgo biloba	13
LncRNA NEAT1 accelerates breast cancer progression through regulating miR-410-3p/ CCND1 axis	13
Circulating microRNAs: Challenges with their use as liquid biopsy biomarkers	13
Circular RNA circ_0000039 enhances gastric cancer progression through miR-1292-5p/DEK axis	13
E2F1 transcriptionally regulates CCNA2 expression to promote triple negative breast cancer tumorigenicity	12
MCM5 urine expression (ADXBLADDER) is a reliable biomarker of high-risk non- muscle-invasive bladder cancer recurrence: A prospective matched case-control study	12
Three plasma-based microRNAs as potent diagnostic biomarkers for endometrial cancer	12
Long intergenic noncoding RNA LINC00173 as a potential serum biomarker for diagnosis of non-small-cell lung cancer	12
lncRNA ELFN1-AS1 predicts poor prognosis and promotes tumor progression of non-small cell lung cancer by sponging miR-497	12
LRP4 promotes migration and invasion of gastric cancer under the regulation of microRNA-140-5p	12
An increased level of MiR-222-3p is associated with TMP2 suppression, ERK activation and is associated with metastasis and a poor prognosis in renal clear cell carcinoma	12
Curcumin increases crizotinib sensitivity through the inactivation of autophagy via epigenetic modulation of the miR-142-5p/Ulk1 axis in non-small cell lung cancer	12
CEACAM5 overexpression is a reliable characteristic of CD133-positive colorectal cancer stem cells	12
Usefulness of protein-based salivary markers in the diagnosis of oral potentially malignant disorders: A systematic review and meta-analysis	11
m5C RNA methyltransferase-related gene NSUN4 stimulates malignant progression of hepatocellular carcinoma and can be a prognostic marker	11
Identification of genes in hepatocellular carcinoma induced by non-alcoholic fatty liver disease	11
Identification of Let-7f-5p as a novel biomarker of recurrence in non-muscle invasive bladder cancer	11
DSCAM-AS1 accelerates cell proliferation and migration in osteosarcoma through miR-186-5p/GPRC5A signaling	11
DEPDC1 upregulation promotes cell proliferation and predicts poor prognosis in patients with gastric cancer	11
Arsenic trioxide-induced upregulation of miR-1294 suppresses tumor growth in hepatocellular carcinoma by targeting TEAD1 and PIM1	11
Gene sequencing and expression of Raf-1 in lymphatic metastasis of hypopharyngeal carcinoma	11
TRIP13 promotes lung cancer cell growth and metastasis through AKT/mTORC1/c-Myc signaling	10
Identification of potential serum biomarkers for simultaneously classifying lung adenocarcinoma, squamous cell carcinoma and small cell carcinoma	10
Application of a multiplex urinalysis test for the prediction of intravesical BCG treatment response: A pilot study	10
Circulating microRNA-762 upregulation in colorectal cancer may be accompanied by Wnt-1/β-catenin signaling	10
Expression of cancer stem cell markers CD24, EPHA1 and CD9 and their correlation with clinical outcome in epithelial ovarian tumours	10
Long noncoding RNA MAGI2-AS3 inhibits bladder cancer progression through MAGI2/PTEN/epithelial-mesenchymal transition (EMT) axis	10
LINC00174 is a favorable prognostic biomarker in glioblastoma via promoting proliferative phenotype	10
Mammalian SIRT4 is a tumor suppressor of clear cell renal cell carcinoma by inhibiting cancer proliferation, migration and invasion	10
An integrative pan-cancer analysis of COPB1 based on data mining	10
Isolation of extracellular vesicle with different precipitation-based methods exerts a tremendous impact on the biomarker analysis for clinical plasma samples	10
MiR-96-5p induced NDRG1 deficiency promotes prostate cancer migration and invasion through regulating the NF-κB signaling pathway	10
Upregulation of microRNA-1303 is a potential prognostic marker of non-small cell lung cancer	9
Long non-coding RNA LINC01116 regulated miR-744-5p/SCN1B axis to exacerbate lung squamous cell carcinoma	9

Immunosuppressive receptor LILRB1 acts as a potential regulator in hepatocellular carcinoma by integrating with SHP1	9
Clinical powers of Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) for head-neck squamous cell carcinoma	9
Identifying GNG4 might play an important role in colorectal cancer TMB	9
Radiomics model of 18F-FDG PET/CT imaging for predicting disease-free survival of early-stage uterine cervical squamous cancer	9
Lymphocyte C-reactive protein ratio: A new biomarker to predict early complications after gastrointestinal oncologic surgery	9
MiR-196a promoted cell migration, invasion and the epithelial-mesenchymal transition by targeting HOXA5 in osteosarcoma	9
Weighted correlation network analysis identifies FN1, COL1A1 and SERPINE1 associated with the progression and prognosis of gastric cancer	9
USP7 promotes hepatoblastoma progression through activation of PI3K/AKT signaling pathway	9
Molecular alterations in non-functioning pituitary adenomas	9
MicroRNA-204/CREB5 axis regulates vasculogenic mimicry in breast cancer cells	9
Expression of FOXM1 and Aurora-A predicts prognosis and sorafenib efficacy in patients with hepatocellular carcinoma	8
Eight-gene signature predicts recurrence in lung adenocarcinoma	8
LncRNA LINC00858 enhances cervical cancer cell growth through miR-3064-5p/ VMA21 axis	8
YTHDF1 amplification is correlated with worse outcome and lower immune cell infiltrations in breast cancer	8
MicroRNA-629 promotes the tumorigenesis of non-small-cell lung cancer by targeting FOXO1 and activating PI3K/AKT pathway	8
Molecular mechanisms, immune cell infiltration, and potential drugs for prostate cancer	8
Long non-coding RNA MIR4435-1HG promotes cancer growth in clear cell renal cell carcinoma	8
LCP1 is a prognostic biomarker correlated with immune infiltrates in gastric cancer	8
Serum netrin-1 as a biomarker for colorectal cancer detection	8
Downregulation of ASF1B inhibits tumor progression and enhances efficacy of cisplatin in pancreatic cancer	8
Claudin-6 is down-regulated in gastric cancer and its potential pathway	8
GR silencing impedes the progression of castration-resistant prostate cancer through the JAG1/NOTCH2 pathway via up-regulation of microRNA-143-3p	8
CmP signaling network unveils novel biomarkers for triple negative breast cancer in African American women	8
Methylation of FBN1, SPG20, ITF2, RUNX3, SNCA, MLH1, and SEPT9 genes in circulating cell-free DNA as biomarkers of colorectal cancer	8
Targeting PKM2 promotes chemosensitivity of breast cancer cells in vitro and in vivo	8
FOXD3-AS1 suppresses the progression of non-small cell lung cancer by regulating miR-150/SRCIN1axis	8
Increased ANXA5 expression in stomach adenocarcinoma infers a poor prognosis and high level of immune infiltration	8
Screening of cervical cancer-related hub genes based on comprehensive bioinformatics analysis	8
Identification of diagnostic and prognostic lncRNA biomarkers in oral squamous carcinoma by integrated analysis and machine learning	8
LncRNA HCG11 promotes 5-FU resistance of colon cancer cells through reprogramming glucose metabolism by targeting the miR-144-3p-PDK4 axis	8
CDT1 facilitates metastasis in prostate cancer and correlates with cell cycle regulation	8
KCNN4 promotes the progression of lung adenocarcinoma by activating the AKT and ERK signaling pathways	8
Identification of differentially expressed circular RNAs in human nasopharyngeal carcinoma	8
Prognostic value of circulating Bcl-2 and anti-p53 antibodies in patients with breast cancer: A long term follow-up (17.5 years)	8
Association between baseline Controlling Nutritional Status score and clinical outcomes of patients with multiple myeloma	8
Upregulated histone deacetylase 2 gene correlates with the progression of oral squamous cell carcinoma	8
Ascites in ovarian cancer: MicroRNA deregulations and their potential roles in ovarian carcinogenesis	7
MiR-3666 serves as a tumor suppressor in ovarian carcinoma by down-regulating AK4 via targeting STAT3	7
Lipocalin-2: A novel diagnostic marker for hepatocellular carcinoma	7
Pre-surgical level of von Willebrand factor as an evident indicator of breast cancer recurrence	7
Salivary KLK5 and uPA are potential biomarkers for malignant transformation of OLK and OLP	7
Clinical value of tumor-associated antigens and autoantibody panel combination detection in the early diagnostic of lung cancer	7
Optimal vocabulary selection approaches for privacy-preserving deep NLP model training for information extraction and cancer epidemiology	7
Predictions of the dysregulated competing endogenous RNA signature involved in the progression of human lung adenocarcinoma	7
Higher platelet distribution width is associated with unfavorable prognosis in ovarian cancer	7
Carboxypeptidase E down-regulation regulates transcriptional and epigenetic profiles in pancreatic cancer cell line: A network analysis	7
The α2δ1 subunit of the voltage-gated calcium channel as a potential candidate for breast cancer tumor initial cells biomarker	7
Circulating cell-free DNA variables as marker of ovarian cancer patients: A pilot study	7
Applications of artificial intelligence (AI) in ovarian cancer, pancreatic cancer, and image biomarker discovery	7
Coiled-coil domain-containing protein-124 (Ccdc124) is a novel RNA binding factor up-regulated in endometrial, ovarian, and urinary bladder cancers	7
Early onset of severe lymphopenia during definitive radiotherapy correlates with mean body dose and predicts poor survival in cervical cancer	7
MicroRNAs MiR-15a and MiR-26a cooperatively regulate O-GlcNAc-transferase to control proliferation in clear cell renal cell carcinoma	7
POM121 promotes proliferation and metastasis in non-small-cell lung cancer through TGF-β/SMAD and PI3K/AKT pathways	7
A fourteen-lncRNA risk score system for prognostic prediction of patients with non-small cell lung cancer	6
CD133 expression and clinicopathologic significance in benign and malignant breast lesions	6
Identifying the mRNAs associated with Bladder cancer recurrence	6
Role of Tim-3 in regulating tumorigenesis, inflammation, and antitumor immunity therapy	6
The relationship between LncRNAs and lung adenocarcinoma as well as their ceRNA network	6
Gene expression profiling after LINC00472 overexpression in an NSCLC cell line1	6
Ubiquitination and degradation of MGMT by TRIM72 increases the sensitivity of uveal melanoma cells to Dacarbazine treatment	6
Profile of sphingolipid-related genes and its association with prognosis highlights sphingolipid metabolism in oral cancer	6
SATB-1 and Her2 as predictive molecular and immunohistochemical markers for urothelial cell carcinoma of the bladder	6
Nomogram based on pre-treatment inflammatory biomarkers predicting survival in patients with head and neck soft tissue sarcoma	6
High expression of IGF2-derived intronic miR-483 predicts outcome in hepatoblastoma	6
Cytoplasmic expression of DCLK1-S, a novel DCLK1 isoform, is associated with tumor aggressiveness and worse disease-specific survival in colorectal cancer	6
RETRACTED: miR-199a-5p suppresses epithelial- mesenchymal-transition in anaplastic thyroid carcinoma cells via targeting Snail signals	6
Prognostic and predictive significance of the tumor microenvironment in hepatocellular carcinoma	6
Molecular alterations in oral cancer between tobacco chewers and smokers using serum proteomics	6
Knockdown CYP2S1 inhibits lung cancer cells proliferation and migration	6
Progressive alteration of DNA methylation of Alu, MGMT, MINT2, and TFPI2 genes in colonic mucosa during colorectal cancer development	6
Knockdown of annexin VII enhances nasopharyngeal carcinoma cell radiosensitivity in vivo and in vitro	6