Molecular Oncology

Papers
(The median citation count of Molecular Oncology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Issue Information174
100
PoDCall: a robust tool for automated droplet classification in DNA‐methylation droplet digital PCR98
64
Correction to “SPT6 recruits SND1 to co‐activate human telomerase reverse transcriptase to promote colon cancer progression”57
Whole‐genome sequencing of cell‐free DNA reveals DNA of tumor origin in plasma from patients with 46
Correction to “Mutant p53 proteins counteract autophagic mechanism sensitizing cancer cells to mTOR inhibition”41
Interaction between membranous EBP50 and myosin 9 as a favorable prognostic factor in ovarian clear cell carcinoma39
Lysosome‐dependent FOXA1 ubiquitination contributes to luminal lineage of advanced prostate cancer38
NKG2A and circulating extracellular vesicles are key regulators of natural killer cell activity in prostate cancer after prostatectomy38
Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity38
Evaluation of two new highly multiplexed PCR assays as an alternative to next‐generation sequencing for IDH1/2 mutation detection36
Development of an optimized, non‐stem cell line for intranasal delivery of therapeutic cargo to the central nervous system35
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer35
Issue Information34
Nanosecond pulsed electric field ablation‐induced modulation of sphingolipid metabolism is associated with Ly6c2 + mononuc34
Prospective clinical sequencing of 1016 Chinese prostate cancer patients: uncovering genomic characterization and race disparity34
Prognostic and predictive impact of gene expression in node‐positive early breast cancer patients receiving dose‐dense versus standard‐dose adjuvant chemotherapy34
The selenoenzyme type I iodothyronine deiodinase: a new tumor suppressor in ovarian cancer33
Unraveling LINE ‐1 retrotransposition in head and neck squamous cell carcinoma33
PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer30
Exosomes secreted by ST3GAL5high cancer cells promote peritoneal dissemination by establishing a premetastatic microenvironment30
An arms‐race against resistance: leukemic stem cells and lineage plasticity29
Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐ CD 73/anti‐ 28
Expanding a precision medicine platform for malignant peripheral nerve sheath tumors: New patient‐derived orthotopic xenografts, cell lines and tumor entities28
Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1 28
Ovarian cancer relies on the PDGFRβ –fibronectin axis for tumorsphere formation and metastatic spread26
The multispecies microbial cluster of Fusobacterium , Parvimonas , Bacteroides 26
Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo26
Targeted therapy of advanced parathyroid carcinoma guided by genomic and transcriptomic profiling25
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for 25
Gene signature predicting recurrence in oral squamous cell carcinoma is characterized by increased oxidative phosphorylation25
Precision Cancer Medicine 2.0—Oncology in the postgenomic era25
Disruption of tp53 leads to cutaneous nevus and melanoma formation in Xenopus tropicalis24
Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma23
Hijacking the BAF complex: the mechanistic interplay of ARID1A and EWS::FLI1 in Ewing sarcoma23
DNA methylation and expression of MAPRE3 affect overall survival of23
New retinoblastoma (RB) drug delivery approaches: anti‐tumor effect of atrial natriuretic peptide (ANP)‐conjugated hyaluronic‐acid‐coated gold nanoparticles for intraocular treat22
Cancer cachexia: biomarkers and the influence of age22
Academia and society should join forces to make anti‐cancer treatments more affordable22
Correction to: Clinical and biological relevance of the transcriptomic‐based prostate cancer metastasis subtypes MetA‐C22
RETRACTION : Long Noncoding RNA ZNF667‐AS1 Reduces Tumor Invasion and Metastasis in Cervical Cancer by Counteracting Microrna‐93‐3p‐Dependent PEG3 Downregulation22
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer22
Proteome‐based molecular subtyping and therapeutic target prediction in gastric cancer21
Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration21
ANGPTL2 ‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion21
Germline variants in CDKN2A wild‐type melanoma prone families21
Integration of single‐cell and bulk RNA ‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer20
Issue Information20
Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer20
E2A selectively regulates TGF‐β–induced apoptosis in KRAS ‐mutant non‐small cell lung cancer20
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology20
A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma20
Issue Information20
Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic–mitochondrial tricarboxylic acid cycle that can be targeted for therapeutic purposes in prostate cancer20
Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient‐derived xenograft models20
Rational combination of SHP2 and mTOR inhibition for the treatment of hepatocellular carcinoma20
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Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption19
Analysis of genomic and immune intratumor heterogeneity in linitis plastica via multiregional exome and T‐cell receptor sequencing19
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DRD1 suppresses cell proliferation and reduces EGFR activation and PD‐L1 18
Tetraploidy‐linked sensitization to CENP‐E inhibition in human cells18
Retraction statement: Consistency analysis of microRNA ‐arm expression reveals microRNA ‐369‐5p/3p18
Correction to “The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma”18
Sustained cancer‐relevant alternative RNA splicing events driven by PRMT5 in high‐risk neuroblasto18
Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples18
The LIN28B –let‐7– PBK pathway is essential for group 3 medulloblastoma tumor growth and survival17
Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK<17
European Code Against Cancer, 5th edition – cancer‐causing infections and related interventions17
Cancer as an infective disease: the role of EVs in tumorigenesis17
Serine protease inhibitors decrease metastasis in prostate, breast, and ovarian cancers17
Targeting protein folding in N‐Myc‐driven medulloblastoma17
A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications17
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity16
Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic 16
Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment16
Correction to “The prostate metastasis suppressor gene NDRG 1 differentially regulates cell motility and invasion”16
Molecular cancer prevention: Intercepting disease16
MMP14 expression and collagen remodelling support uterine leiomyosarcoma aggressiveness16
Intein‐based modular chimeric antigen receptor platform for specific CD19 / CD20 co‐targeting16
Issue Information16
Functional loss of ERBB receptor feedback inhibitor 1 ( MIG6 ) promotes glioblastoma tumorigenesis15
Rodent models of tumours of the central nervous system15
RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma15
Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorourac15
Post‐prostatic‐massage urine exosomes of men with chronic prostatitis/chronic pelvic pain syndrome carry prostate‐cancer‐typical micro RNA s and acti15
PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism15
Long noncoding RNAs with peptide‐encoding potential identified in esophageal squamous cell carcinoma: KDM4A‐AS1‐encoded peptide weakens cancer cell viability and migratory capacity14
Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients14
Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer14
Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models14
Assay‐agnostic spatial profiling detects tumor microenvironment signatures: new diagnostic insights for triple‐negative breast cancer14
Preclinical efficacy of carfilzomib in BRAF ‐mutant colorectal cancer models14
Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation14
Abstracts14
Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7 ‐mutated 14
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential14
SETD2 loss in renal epithelial cells drives epithelial‐to‐mesenchymal transition in a TGF‐β‐independent manner14
Interpreting the effects of DNA polymerase variants at the structural level14
KRAS inhibitors: going noncovalent14
Potential therapeutic targeting of BK Ca channels in glioblastoma treatment14
Assembly of glioblastoma tumoroids and cerebral organoids: a 3Din vitro model for tumor cell invasion13
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers13
Issue Information13
ATF4 ‐mediated stress response as a therapeutic vulnerability in chordoma13
Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel13
European Code Against Cancer, 5th edition – tobacco and nicotine containing products, second‐hand smoke, alcohol and cancer13
Issue Information13
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma13
A rapid, multiplex digital PCR assay to detect gene variants and fusions in non‐small cell lung cancer13
Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of 13
13
SOS2 modulates the threshold of EGFR signaling to regulate osimertinib efficacy and resistance in lung adenocarcinoma13
Retraction Statement: Circ‐TCF4 .85 silencing inhibits cancer progression through microRNA ‐486‐5p12
PELP1 inhibition by SMIP34 reduces endometrial cancer progression via attenuation of ribosomal biogenesis12
Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA 12
Plasma extrachromosomal circular DNA as a biomarker in EGFR ‐targeted therapy of non‐small cell lu12
Lipid metabolism in B cell biology12
Liver X receptors induce antiproliferative effects in basal‐like breast cancer12
Expression of circular RNAs in myelodysplastic neoplasms and their association with mutations in the splicing factor gene SF3B112
LDAcoop : Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro12
CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cance12
The correlation between clinical outcomes and genomic analysis with high risk factors for the progression of osteosarcoma12
Atezolizumab and stereotactic body radiotherapy in patients with advanced non‐small cell lung cancer: safety, clinical activity and ctDNA responses—t12
PP2A ‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells12
In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma12
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance12
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs12
Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay12
EXPRESSION OF CONCERN: DIMP53 ‐1: A Novel Small‐Molecule Dual Inhibitor of p53– MDM2 /X Interactio12
Postbiotics of Lacticaseibacillus paracasei CECT 9610 and Lactiplantibacillus plantarum 11
Metabolism in the tumor cell and beyond11
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway11
Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic ce11
Targeting senescence as an anticancer therapy11
Microglia and macrophages in glioblastoma: landscapes and treatment directions11
Copy number variations contribute to malignant tumor development in children with serious birth defects11
COMPPMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells11
GALNT2 promotes invasiveness of colorectal cancer cells partly through AXL11
Enhanced reversal of ABCG2‐mediated drug resistance by replacing a phenyl ring in baicalein with a meta ‐carborane11
SMG1 , a nonsense‐mediated mRNA decay ( NMD ) regulator, as a candi11
Immune escape of colorectal tumours via local LRH‐1/Cyp11b1‐mediated synthesis of immunosuppressive glucocorticoids11
Expression of Concern: T‐ LAK cell‐originated protein kinase ( TOPK ): an emerging prognostic biom11
Liquid biopsy: circulating tumor DNA monitors neoadjuvant chemotherapy response and prognosis in stage II/III gastric cancer11
CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma11
SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radi11
Immune evasion: An imperative and consequence of MYC deregulation11
Thioredoxin‐interacting protein ( TXNIP ) is a substrate of the NEDD4 ‐like 11
Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional valida11
The invariant chain CD74 protein is a cell surface binding partner of TIMP‐1 in breast cancer cells11
From bedside to portable and wearable: development of a conformable ultrasound patch for deep breast tissue imaging11
Issue Information11
cAMP ‐phosphodiesterase 4D7 ( PDE4D7 ) forms a 11
Protein palmitoylation in cancer: molecular functions and therapeutic potential11
Loss of Lkb1 cooperates with Braf V600E 11
Comparative membrane lipidomics of hepatocellular carcinoma cells reveals diacylglycerol and ceramide as key regulators of Wnt/β‐catenin signaling and tumor growth11
The polyamine transporter ATP13A3 mediates difluoromethylornithine‐induced polyamine uptake in neuroblastoma11
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients11
TREX1 , a predator for treating MSI ‐H tumors?10
Investigation of somatic mutation profiles and tumor evolution of primary oropharyngeal cancer and sequential lymph node metastases using multiregional whole‐exome sequencing10
Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma10
ERBB2 mutations define a subgroup of endometrial carcinomas associated with high tumor mutational burden and the microsatellite instability‐high ( M10
Issue Information10
Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia10
Engineered extracellular vesicles enriched with the miR ‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer10
Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with 10
Identification and targeting of a HES1‐YAP1‐CDKN1C functional interaction in fusion‐negative rhabdomyosarcoma10
Transcriptomic pan‐cancer analysis using rank‐based Bayesian inference10
Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early no10
Oncogenic composite mutations can be predicted by co‐mutations and their chromosomal location10
Ribosome biogenesis‐based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: 10
Unraveling epigenetic heterogeneity across gastrointestinal adenocarcinomas through a standardized analytical framework10
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The roles and applications of extracellular vesicles in cancer10
Identifying the personalized driver gene sets maximally contributing to abnormality of transcriptome phenotype in glioblastoma multiforme individuals10
Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ ALL pediatric patients with high 10
Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade10
Low levels of WRAP53 predict decreased efficacy of radiotherapy and are prognostic for local recurrence and death from breast cancer: a long‐term fol10
Inhibition of CDCP1 by 8‐isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer trea10
Integrated analysis of racial disparities in genomic architecture identifies a trans‐ancestry prognostic subtype in bladder cancer10
The prevalence and prognosis of next‐generation therapeutic targets in metastatic castration‐resistant prostate cancer10
Interferon regulatory factor 4 modulates epigenetic silencing and cancer‐critical pathways in melanoma cells10
Current status of precision oncology in adult glioblastoma10
Advanced strategies in improving the immunotherapeutic effect of CAR‐T cell therapy10
PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model10
Levels of circulating tumor DNA correlate with tumor volume in gastro‐intestinal stromal tumors: an exploratory long‐term follow‐up study10
Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E 10
LIM domain‐containing protein Ajuba inhibits chemotherapy‐induced apoptosis by negatively regulating p53 stability in colorectal cancer cells9
TRAILPEG ‐Apt‐ PLGA nanosystem as an aptamer‐targeted drug deliv9
Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog 9
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression9
Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2 ‐positive cancers9
Overexpression of the pro‐protein convertase furin predicts prognosis and promotes papillary thyroid carcinoma progression and metastasis through RAF 9
Inhibition of acyl‐ CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction9
Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients9
Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker9
Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1 / RIPK1 signal9
PP2A methylesterase PME ‐1 suppresses anoikis and is associated with therapy relapse of 9
Predictors of response and rational combinations for the novel MCL ‐1 inhibitor MIK665 in acute my9
Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities9
Transcription factor 4 is a key mediator of oncogenesis in neuroblastoma by promoting MYC activity9
The critical role of DNA damage‐inducible transcript 4 ( DDIT4 ) in stemness character of leukemia9
MASH as an emerging cause of hepatocellular carcinoma: current knowledge and future perspectives9
Plasma membrane SK2 channel activity regulates migration and chemosensitivity of high‐grade serous ovarian cancer cells9
Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance9
In vitro and in silico modelling of ROS1 ‐positive non‐small cell lung canc9
Viral mimicry evasion: a new role for oncogenic KRAS mutations9
CDK 11 inhibition induces cytoplasmic p21 WAF 1 9
Ex vivo mapping of enhancer networks that define the transcriptional program driving melanoma metastasis9
Transcriptional analysis of landmark molecular pathways in lung adenocarcinoma results in a clinically relevant classification with potential therapeutic implications9
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Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen ther9
Resistance prediction in high‐grade serous ovarian carcinoma with neoadjuvant chemotherapy using data‐independent acquisition proteomics and an ovary‐specific spectral library9
Bovine meat and milk factor protein expression in tumor‐free mucosa of colorectal cancer patients coincides with macrophages and might interfere with patient survival9
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B79
Novel insights into molecular patterns of ROS1 fusions in a large Chinese NSCLC cohort: a multicenter study9
Deciphering metabolic crosstalk in context: lessons from inflammatory diseases9
Cell‐free chromatin immunoprecipitation can determine tumor gene expression in lung cancer patients9
Targeting p38α in cancer: challenges, opportunities, and emerging strategies9
Enhancing therapeutic efficacy in triple‐negative breast cancer and melanoma: synergistic effects of modulated electro‐hyperthermia (mEHT) with NSAIDs especially COX‐2 inhibition in 9
Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product9
ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration8
Exportin 1‐mediated nuclear/cytoplasmic trafficking controls drug sensitivity of classical Hodgkin's lymphoma8
Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non‐small cell lung cancer (NSCLC) through inhibition of HIF‐1α8
RNA m6Amethylation in cancer8
A novel pipeline for prioritizing cancer type‐specific therapeutic vulnerabilities using DepMap identifies PAK2 as a target in head and neck squamous cell carcinomas8
Screening for lung cancer: A systematic review of overdiagnosis and its implications8
Detection of colorectal‐cancer‐associated bacterial taxa in fecal samples using next‐generation sequencing and 19 newly established q PCR assays8
Cadherin‐11 increases tumor cell proliferation and metastatic potential via Wnt pathway activation8
Optimising the European Code Against Cancer, 5th edition, to increase awareness of avoidable cancer risks in all socioeconomic groups8
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer8
Chimeric diphtheria toxin– CCL8 cytotoxic peptide for breast cancer management8
Recurrence/prognosis estimation using a molecularly positive surgical margin‐based model calls for alternative curative strategies in pIIIA/N2 NSCLC8
European Code Against Cancer, 5th edition – organised cancer screening programmes8
RETRACTION : Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and Upar in Glioma8
Tumour immunogenicity goes with the (mitochondrial electron) flow8
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RETRACTION: NNK From Tobacco Smoking Enhances Pancreatic Cancer Cell Stemness and Chemoresistance by Creating a β2AR‐Akt Feedback Loop That Activates Autophagy8
Malformin C preferentially kills glioblastoma stem‐like cells via concerted induction of proteotoxic stress and autophagic flux blockade8
Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/ mTOR and 8
Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and 8
Correction to “Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian can8
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?8
Next‐generation proteomics improves lung cancer risk prediction8
MYC and therapy resistance in cancer: risks and opportunities8
Issue Information8
Endometrioid ovarian carcinoma landscape: pathological and molecular characterization8
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER + breast cancer8
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