Molecular Oncology

Papers
(The TQCC of Molecular Oncology is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Targeting immunogenic cell death in cancer400
Physical activity, obesity and sedentary behavior in cancer etiology: epidemiologic evidence and biologic mechanisms216
Elesclomol induces copper‐dependent ferroptosis in colorectal cancer cells via degradation of ATP7A122
Clinical utility of circulating tumor cells: an update103
DNA in extracellular vesicles: biological and clinical aspects102
Clearance of therapy‐induced senescent tumor cells by the senolytic ABT‐263 via interference with BCL‐XL–BAX interaction91
The effect of surgical trauma on circulating free DNA levels in cancer patients—implications for studies of circulating tumor DNA90
Prevention and treatment of radiotherapy‐induced side effects85
Exosome‐transmitted circ_MMP2 promotes hepatocellular carcinoma metastasis by upregulating MMP284
Cellular senescence in cancer: from mechanisms to detection80
Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis78
A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment69
Image guidance in radiation therapy for better cure of cancer62
Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy60
Dual inhibition of TGF‐β and PD‐L1: a novel approach to cancer treatment59
Global mapping of cancers: The Cancer Genome Atlas and beyond59
Overcoming the senescence‐associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer59
Identification and validation of a combined hypoxia and immune index for triple‐negative breast cancer59
iRGD‐modified exosomes effectively deliver CPT1A siRNA to colon cancer cells, reversing oxaliplatin resistance by regulating fatty acid oxidation58
CircFNDC3B sequestrates miR‐937‐5p to derepress TIMP3 and inhibit colorectal cancer progression58
Autophagy, the innate immune response and cancer54
AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response53
LncRNA NKX2‐1‐AS1 promotes tumor progression and angiogenesis via upregulation of SERPINE1 expression and activation of the VEGFR‐2 signaling pathway in gastric cancer50
Distribution and prognostic significance of gluconeogenesis and glycolysis in lung cancer50
Provision and use of radiotherapy in Europe49
Doxorubicin‐induced senescence promotes stemness and tumorigenicity in EpCAM−/CD133− nonstem cell population in hepatocellular carcinoma cell line, HuH‐747
METTL3/YTHDF2 m6A axis accelerates colorectal carcinogenesis through epigenetically suppressing YPEL547
Cancer diagnostics based on plasma protein biomarkers: hard times but great expectations46
FOXD1‐AS1 regulates FOXD1 translation and promotes gastric cancer progression and chemoresistance by activating the PI3K/AKT/mTOR pathway44
LncRNA AATBC regulates Pinin to promote metastasis in nasopharyngeal carcinoma44
Enhancing cancer‐associated fibroblast fatty acid catabolism within a metabolically challenging tumor microenvironment drives colon cancer peritoneal metastasis44
Immune response drives outcomes in prostate cancer: implications for immunotherapy44
Detection and relevance of epigenetic markers on ctDNA: recent advances and future outlook44
Serum small extracellular vesicle‐derived LINC00853 as a novel diagnostic marker for early hepatocellular carcinoma44
Neuroendocrine subtypes of small cell lung cancer differ in terms of immune microenvironment and checkpoint molecule distribution44
Early assessment of circulating tumor DNA after curative‐intent resection predicts tumor recurrence in early‐stage and locally advanced non‐small‐cell lung cancer43
Tobacco control policies in the 21st century: achievements and open challenges43
Classification of diffuse lower‐grade glioma based on immunological profiling43
Variability of EGFR exon 20 insertions in 24 468 Chinese lung cancer patients and their divergent responses to EGFR inhibitors41
Circulating platelets as liquid biopsy sources for cancer detection39
Cellular senescence and the tumour microenvironment38
Circulating tumor cell profiling for precision oncology37
A novel prognostic mRNA/miRNA signature for esophageal cancer and its immune landscape in cancer progression36
Deubiquitinase PSMD14 promotes ovarian cancer progression by decreasing enzymatic activity of PKM235
Circ_0008039 supports breast cancer cell proliferation, migration, invasion, and glycolysis by regulating the miR‐140‐3p/SKA2 axis35
TGFBI modulates tumour hypoxia and promotes breast cancer metastasis34
Linc‐ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR‐194‐3p targeting MECP234
Fragment‐based drug discovery—the importance of high‐quality molecule libraries34
Retracted: Exosomal miR‐1255b‐5p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial‐to‐mesenchymal transition33
Circulating exosomal miR‐363‐5p inhibits lymph node metastasis by downregulating PDGFB and serves as a potential noninvasive biomarker for breast cancer33
Human fibronectin extra domain B as a biomarker for targeted therapy in cancer32
Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy31
Combination therapy with androgen receptor N‐terminal domain antagonist EPI‐7170 and enzalutamide yields synergistic activity in AR‐V7‐positive prostate cancer31
Metabolomic profile of cancer stem cell‐derived exosomes from patients with malignant melanoma31
Estrogen receptor α promotes lung cancer cell invasion via increase of and cross‐talk with infiltrated macrophages through the CCL2/CCR2/MMP9 and CXCL12/CXCR4 signaling pathways31
Periostin+cancer‐associated fibroblasts promote lymph node metastasis by impairing the lymphatic endothelial barriers in cervical squamous cell carcinoma31
SENP3 loss promotes M2 macrophage polarization and breast cancer progression30
The FABP12/PPARγ pathway promotes metastatic transformation by inducing epithelial‐to‐mesenchymal transition and lipid‐derived energy production in prostate cancer cells30
FOXM1D potentiates PKM2‐mediated tumor glycolysis and angiogenesis30
Targeted inhibition of STAT3 induces immunogenic cell death of hepatocellular carcinoma cells via glycolysis30
Towards a cancer mission in Horizon Europe: recommendations30
LncRNA SOX2‐OT regulates AKT/ERK and SOX2/GLI‐1 expression, hinders therapy, and worsens clinical prognosis in malignant lung diseases30
A novel cell‐free DNA methylation‐based model improves the early detection of colorectal cancer30
Extracellular vesicles and oncogenic signaling29
Resistance to DNA repair inhibitors in cancer29
SMARCA4 mutations in KRAS‐mutant lung adenocarcinoma: a multi‐cohort analysis29
Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients29
Characterization of super‐enhancer‐associated functional lncRNAs acting as ceRNAs in ESCC29
Multifaceted activities of transcription factor EB in cancer onset and progression28
EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression28
Darolutamide antagonizes androgen signaling by blocking enhancer and super‐enhancer activation28
Advances in optical gastrointestinal endoscopy: a technical review28
CircRNA EPHB4 modulates stem properties and proliferation of gliomas via sponging miR‐637 and up‐regulating SOX1028
Vitamin D supplementation to the older adult population in Germany has the cost‐saving potential of preventing almost 30 000 cancer deaths per year28
Circular RNA profiling identifies circ102049 as a key regulator of colorectal liver metastasis28
HPV‐related methylation‐based reclassification and risk stratification of cervical cancer27
Long noncoding RNA SNHG12 induces proliferation, migration, epithelial–mesenchymal transition, and stemness of esophageal squamous cell carcinoma cells via post‐transcriptional regulation of BMI1 and 27
Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis27
Autophagy at the intersection of aging, senescence, and cancer27
Retracted: Long non‐coding RNA PGM5‐AS1 promotes epithelial‐mesenchymal transition, invasion and metastasis of osteosarcoma cells by impairing miR‐140‐5p‐mediated FBN1 inhibition27
Long noncoding RNA DANCR confers cytarabine resistance in acute myeloid leukemia by activating autophagy via the miR‐874‐3P/ATG16L1 axis27
The DNA methylation landscape of hematological malignancies: an update27
LAMC1 upregulation via TGFβ induces inflammatory cancer‐associated fibroblasts in esophageal squamous cell carcinoma via NF‐κB–CXCL1–STAT327
Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA27
Irradiation‐induced polyploid giant cancer cells are involved in tumor cell repopulation via neosis26
Histological and mutational profile of diffuse gastric cancer: current knowledge and future challenges26
Long noncoding RNA LINC01578 drives colon cancer metastasis through a positive feedback loop with the NF‐κB/YY1 axis26
Molecular and clinicopathological characteristics of ROS1‐rearranged non‐small‐cell lung cancers identified by next‐generation sequencing26
Targeting KRAS mutant lung cancer: light at the end of the tunnel26
Metabolic enzyme ACSL3 is a prognostic biomarker and correlates with anticancer effectiveness of statins in non‐small cell lung cancer26
Pericyte‐secreted IGF2 promotes breast cancer brain metastasis formation26
Single‐cell transcriptomics reveal the intratumoral landscape of infiltrated T‐cell subpopulations in oral squamous cell carcinoma25
Autophagy activation and SREBP‐1 induction contribute to fatty acid metabolic reprogramming by leptin in breast cancer cells25
Autophagy inhibits cancer stemness in triple‐negative breast cancer via miR‐181a‐mediated regulation of ATG5 and/or ATG2B24
Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study24
Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression24
Fluid shear stress activates YAP to promote epithelial–mesenchymal transition in hepatocellular carcinoma24
The STAT3‐miR‐223‐TGFBR3/HMGCS1 axis modulates the progression of cervical carcinoma24
Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission24
MYC and therapy resistance in cancer: risks and opportunities23
Gene expression profiles of breast cancer metastasis according to organ site23
Cancer‐associated fibroblasts educate normal fibroblasts to facilitate cancer cell spreading and T‐cell suppression23
Long non‐coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR‐345‐5p/RACGAP1‐mediated mitochondrial fission23
Pathological validation and prognostic potential of quantitative MRI in the characterization of pancreas cancer: preliminary experience23
Early detection of hepatocellular carcinoma via liquid biopsy: panel of small extracellular vesicle‐derived long noncoding RNAs identified as markers23
Downregulation of adipose triglyceride lipase by EB viral‐encoded LMP2A links lipid accumulation to increased migration in nasopharyngeal carcinoma23
Rho‐associated protein kinase‐dependent moesin phosphorylation is required for PD‐L1 stabilization in breast cancer23
What will radiation oncology look like in 2050? A look at a changing professional landscape in Europe and beyond23
Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers23
RAF dimer inhibition enhances the antitumor activity of MEK inhibitors in K‐RAS mutant tumors23
Molecular profiling of long‐term responders to immune checkpoint inhibitors in advanced non‐small cell lung cancer23
Role of radiation oncology in modern multidisciplinary cancer treatment22
Prevalence of PRKDC mutations and association with response to immune checkpoint inhibitors in solid tumors22
FUBP1 promotes colorectal cancer stemness and metastasis via DVL1‐mediated activation of Wnt/β‐catenin signaling22
Protein palmitoylation in cancer: molecular functions and therapeutic potential22
Allele‐specific proximal promoter hypomethylation of the telomerase reverse transcriptase gene (TERT) associates with TERT expression in multiple cancers22
The evolutionarily conserved long non‐coding RNA LINC00261 drives neuroendocrine prostate cancer proliferation and metastasis via distinct nuclear and cytoplasmic mechanisms22
Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregulation22
Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancer22
Ribonucleotide reductase small subunit M2 is a master driver of aggressive prostate cancer22
TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status22
Vaccination against HPV: boosting coverage and tackling misinformation22
Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity21
The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas21
Serum markers improve current prediction of metastasis development in early‐stage melanoma patients: a machine learning‐based study21
The lncRNA ‘UCA1’ modulates the response to chemotherapy of ovarian cancer through direct binding to miR‐27a‐5p and control of UBE2N levels21
Defining the dimensions of circulating tumor cells in a large series of breast, prostate, colon, and bladder cancer patients21
Targeting senescence as an anticancer therapy21
Epithelial/mesenchymal heterogeneity of high‐grade serous ovarian carcinoma samples correlates with miRNA let‐7 levels and predicts tumor growth and metastasis21
Molecular testing on bronchial washings for the diagnosis and predictive assessment of lung cancer21
Blood DNA methylation profiles improve breast cancer prediction20
Circulating tumor DNA as a biomarker for monitoring early treatment responses of patients with advanced lung adenocarcinoma receiving immune checkpoint inhibitors20
Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion20
Mutated circulating tumor DNA as a liquid biopsy in lung cancer detection and treatment20
FKBP51 and FKBP52 regulate androgen receptor dimerization and proliferation in prostate cancer cells20
The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings20
A novel prognostic model based on four circulating miRNA in diffuse large B‐cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression20
Occupational cancer burden: the contribution of exposure to process‐generated substances at the workplace20
CircATRNL1 activates Smad4 signaling to inhibit angiogenesis and ovarian cancer metastasis via miR‐37820
Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction20
A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis20
TERT C228T mutation in non‐malignant bladder urothelium is associated with intravesical recurrence for patients with non‐muscle invasive bladder cancer19
Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment19
Discovery and validation of extracellular vesicle‐associated miRNAs as noninvasive detection biomarkers for early‐stage non‐small‐cell lung cancer19
Artificial intelligence in cancer research: learning at different levels of data granularity19
Platelets are recruited to hepatocellular carcinoma tissues in a CX3CL1‐CX3CR1 dependent manner and induce tumour cell apoptosis19
Phosphorylation of the androgen receptor at Ser81 is co‐sustained by CDK1 and CDK9 and leads to AR‐mediated transactivation in prostate cancer19
Mitochondrial DNA mutations in ageing and cancer19
TGF‐β‐induced IGFBP‐3 is a key paracrine factor from activated pericytes that promotes colorectal cancer cell migration and invasion19
High‐throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype‐specific serologically relevant biomarkers19
Viruses in colorectal cancer19
Cancer‐associated fibroblasts promote tumor progression by lncRNA‐mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma18
Immune modulation underpins the anti‐cancer activity of HDAC inhibitors18
A novel circular RNA, hsa_circ_0030998 suppresses lung cancer tumorigenesis and Taxol resistance by sponging miR‐55818
In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor18
Harnessing data science to advance radiation oncology18
Comprehensive cross‐platform comparison of methods for non‐invasive EGFR mutation testing: results of the RING observational trial18
Integrating bulk and single‐cell RNA sequencing reveals cellular heterogeneity and immune infiltration in hepatocellular carcinoma18
The KRAS/Lin28B axis maintains stemness of pancreatic cancer cells via the let‐7i/TET3 pathway18
Constitutive activation of integrin αvβ3 contributes to anoikis resistance of ovarian cancer cells18
E2F1‐activated SPIN1 promotes tumor growth via a MDM2‐p21‐E2F1 feedback loop in gastric cancer18
Oncogenic KRAS mutations enhance amino acid uptake by colorectal cancer cells via the hippo signaling effector YAP118
EWI‐2 controls nucleocytoplasmic shuttling of EGFR signaling molecules and miRNA sorting in exosomes to inhibit prostate cancer cell metastasis18
The ZEB2‐dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer18
TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas18
Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma18
Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression18
The miR‐19b‐3p‐MAP2K3‐STAT3 feedback loop regulates cell proliferation and invasion in esophageal squamous cell carcinoma18
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple‐negative breast cancer17
Benchmarking HLA genotyping and clarifying HLA impact on survival in tumor immunotherapy17
KMT2C promoter methylation in plasma‐circulating tumor DNA is a prognostic biomarker in non‐small cell lung cancer17
Long non‐coding NR2F1‐AS1 is associated with tumor recurrence in estrogen receptor‐positive breast cancers17
Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia‐inducible factor‐1α in colorectal cancer17
DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies17
Integrative analysis of gut microbiome and host transcriptomes reveals associations between treatment outcomes and immunotherapy‐induced colitis17
Multiplex RNA‐based detection of clinically relevant MET alterations in advanced non‐small cell lung cancer17
Patient‐derived organoids as a preclinical platform for precision medicine in colorectal cancer17
ST6GalNAc‐I promotes lung cancer metastasis by altering MUC5AC sialylation16
Pan‐cancer analysis reveals sex‐specific signatures in the tumor microenvironment16
Metagenomic analysis of primary colorectal carcinomas and their metastases identifies potential microbial risk factors16
Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1‐driven acute lymphoblastic leukemia16
PD‐1‐induced T cell exhaustion is controlled by a Drp1‐dependent mechanism16
DNA repair as a shared hallmark in cancer and ageing16
Cotargeting of miR‐126‐3p and miR‐221‐3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling16
SIK2 represses AKT/GSK3β/β‐catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases16
Artificial intelligence‐driven consensus gene signatures for improving bladder cancer clinical outcomes identified by multi‐center integration analysis16
Role of aneuploid circulating tumor cells and CD31+ circulating tumor endothelial cells in predicting and monitoring anti‐angiogenic therapy efficacy in advanced NSCLC16
Neurotensin receptor 1 signaling promotes pancreatic cancer progression16
NGS‐based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment16
Therapeutic targeting with DABIL‐4 depletes myeloid suppressor cells in 4T1 triple‐negative breast cancer model16
Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage16
Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells15
Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer15
Clinical potential of circulating free DNA and circulating tumour cells in patients with metastatic non‐small‐cell lung cancer treated with pembrolizumab15
NOX4 regulates TGFβ‐induced proliferation and self‐renewal in glioblastoma stem cells15
Upregulation of mesothelial genes in ovarian carcinoma cells is associated with an unfavorable clinical outcome and the promotion of cancer cell adhesion15
CD24 blunts the sensitivity of retinoblastoma to vincristine by modulating autophagy15
T2R bitter taste receptors regulate apoptosis and may be associated with survival in head and neck squamous cell carcinoma15
ERK signaling controls productive HIF‐1 binding to chromatin and cancer cell adaptation to hypoxia through HIF‐1α interaction with NPM115
Identification and validation of novel DNA methylation markers for early diagnosis of lung adenocarcinoma15
Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors15
USP35 mitigates endoplasmic reticulum stress‐induced apoptosis by stabilizing RRBP1 in non‐small cell lung cancer15
Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products15
Sphingolipid metabolism in the development and progression of cancer: one cancer's help is another's hindrance15
The Sp1/FOXC1/HOTTIP/LATS2/YAP/β‐catenin cascade promotes malignant and metastatic progression of osteosarcoma15
The MSP‐RON axis stimulates cancer cell growth in models of triple negative breast cancer15
Genomic characterization of small cell carcinomas of the uterine cervix15
Effect of p53 and its N‐terminally truncated isoform, Δ40p53, on breast cancer migration and invasion15
Characterization of PHGDH expression in bladder cancer: potential targeting therapy with gemcitabine/cisplatin and the contribution of promoter DNA hypomethylation15
Mitochondrial STAT3 regulates antioxidant gene expression through complex I‐derived NAD in triple negative breast cancer15
A small molecule targeting CHI3L1 inhibits lung metastasis by blocking IL‐13Rα2‐mediated JNK‐AP‐1 signals15
MIB1 upregulates IQGAP1 and promotes pancreatic cancer progression by inducing ST7 degradation15
Molecular characteristics and tumorigenicity of ascites‐derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer15
VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer15
Characterization of fragment sizes, copy number aberrations and 4‐mer end motifs in cell‐free DNA of hepatocellular carcinoma for enhanced liquid biopsy‐based cancer detection15
SF3B1 mutation in pancreatic cancer contributes to aerobic glycolysis and tumor growth through a PP2A–c‐Myc axis15
Detection of gene mutations and gene–gene fusions in circulating cell‐free DNA of glioblastoma patients: an avenue for clinically relevant diagnostic analysis14
Tetraspanin 1 promotes endometriosis leading to ovarian clear cell carcinoma14
imPlatelet classifier: image‐converted RNA biomarker profiles enable blood‐based cancer diagnostics14
Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells14
USP22‐mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression14
Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations14
Tspan5 promotes epithelial–mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling14
MicroRNA expression profiling with a droplet digital PCR assay enables molecular diagnosis and prognosis of cancers of unknown primary14
BAP1 suppresses prostate cancer progression by deubiquitinating and stabilizing PTEN14
The RNA‐binding protein MEX3A is a prognostic factor and regulator of resistance to gemcitabine in pancreatic ductal adenocarcinoma14
5‐Hydroxymethylcytosine signature in circulating cell‐free DNA as a potential diagnostic factor for early‐stage colorectal cancer and precancerous adenoma14
Tumor and germline next generation sequencing in high grade serous cancer: experience from a large population‐based testing program14
Acquired small cell lung cancer resistance to Chk1 inhibitors involves Wee1 up‐regulation14
microRNA‐99a‐5p induces cellular senescence in gemcitabine‐resistant bladder cancer by targeting SMARCD114
DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer14
BMP9‐ID1 signaling promotes EpCAM‐positive cancer stem cell properties in hepatocellular carcinoma14
Cyr61 from adipose‐derived stem cells promotes colorectal cancer metastasis and vasculogenic mimicry formation via integrin αVβ513
Stratification of follicular thyroid tumours using data‐independent acquisition proteomics and a comprehensive thyroid tissue spectral library13
Integrative analysis of immune‐related multi‐omics profiles identifies distinct prognosis and tumor microenvironment patterns in osteosarcoma13
The sculpting of somatic mutational landscapes by evolutionary forces and their impacts on aging‐related disease13
Targeting the ubiquitin‐proteasome system in a pancreatic cancer subtype with hyperactive MYC13
Assessment of tumor burden and response to therapy in patients with colorectal cancer using a quantitative ctDNA test for methylated BCAT1/IKZF113
MeCP2 drives hepatocellular carcinoma progression via enforcing HOXD3 promoter methylation and expression through the HB‐EGF/EGFR pathway13
Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility – a prospective, translational study13
Retracted: HMGB1 regulates SNAI1 during NSCLC metastasis, both directly, through transcriptional activation, and indirectly, in a RSF1‐IT2‐dependent manner13
Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma13
Co‐occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence13
Metastatic colorectal cancer and type 2 diabetes: prognostic and genetic interactions13
Small extracellular vesicles from malignant ascites of patients with advanced ovarian cancer provide insights into the dynamics of the extracellular matrix13
Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration‐resistant prostate cancer13
The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel‐resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe13
Anti‐pyroptotic function of TGF‐β is suppressed by a synthetic dsRNA analogue in triple negative breast cancer cells13
FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization13
Novel CTRP8‐RXFP1‐JAK3‐STAT3 axis promotes Cdc42‐dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells13
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