Recent Patents on Anti-Cancer Drug Discovery

Papers
(The median citation count of Recent Patents on Anti-Cancer Drug Discovery is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Quercetin Promotes the M1-to-M2 Macrophage Phenotypic Switch During Liver Fibrosis Treatment by Modulating the JAK2/STAT3 Signaling Pathway32
Research Progress on the Anticancer Activity of Plant Polysaccharides25
Patent Selections25
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review21
Acknowledgement to Contributors20
Acknowledgement to Reviewers20
Patent Selections:16
Overview of Inorganic Nanoparticles: An Expanding Horizon in Tumor Therapeutics16
Interplay between RNA Methylation Eraser FTO and Writer METTL3 in Renal Clear Cell Carcinoma Patient Survival15
Fat-soluble Vitamins and Lung Cancer: Where We Are?15
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma Based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing14
The Influence of Wuzhi Capsule on the Pharmacokinetics of Cyclophosphamide13
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma13
Recent Patents on Plant-Derived Nanoparticles and their Potential Application Towards Various Cancer Therapeutics13
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database13
Covalent Inhibitor Screening for Targeting LOXL2: Studied by Virtual Screening and Experimental Validation13
NIFK, a Potential Prognostic and Immunological Biomarker in Pan-- Cancer Analysis, Significantly Regulates Proliferation and Metastasis of Colorectal Cancer12
Patents on PARP-1 Inhibitors for the Management of Cancer from 2017-202312
Upregulation of M6A Reader HNRNPA2B1 Associated with Poor Prognosis and Tumor Progression in Lung Adenocarcinoma12
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer12
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies12
Current Status and Prospects of Camrelizumab, A Humanized Antibody Against Programmed Cell Death Receptor 112
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer11
Distinct Epigenetic Reprogramming, Mitochondrial Patterns, Cellular Morphology, and Cytotoxicity after Bee Venom Treatment11
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy11
Antioxidant, Anti-Inflammatory and Anticancer Activities of the Methanolic Extract of Thottea siliquosa: An In Vitro and In Silico Study11
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration10
Repurposing of Metformin for Cancer Therapy: Updated Patent and Literature Review10
Human Chorionic Gonadotropin Regulates the Smad Signaling Pathway by Antagonizing TGF-β in Giant Cell Tumor of Bone10
Anti-HER2 VHH Targeted Fluorescent Liposome as Bimodal Nanoparticle for Drug Delivery and Optical Imaging9
Development and Evaluation of a Novel Hyaluronic Acid and Chitosan-modified Phytosome for Co-delivery of Oxymatrine and Glycyrrhizin for Combination Therapy9
An Update of Lysine Specific Demethylase 1 Inhibitor: A Patent Review (2016-2020)9
Recent Trend for EGFR-Based and ALK-Based Targets: A Patent Analysis9
Transdermal Drug Delivery: A Step towards Treatment of Cancer8
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA38
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway8
Regression of Breast Cancer Metastases Following Treatment with Irradiated SV-BR-1-GM, a GM-CSF Overexpressing Breast Cancer Cell Line: Intellectual Property and Immune Markers of Response8
Patent Selections8
Tyrosine Kinase Inhibitor Lenvatinib Causes Cardiotoxicity by Inducing Endoplasmic Reticulum Stress and Apoptosis through Activating ATF6, IRE1α and PERK Signaling Pathways8
Anti-EGFR-mAb and 5-Fluorouracil Conjugated Polymeric Nanoparticles for Colorectal Cancer8
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions8
Metal Nanoparticles as Emerging Drug Candidates in the Management of Cancers and Microbial Infectious Diseases7
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta- Analysis and Systematic Review7
The m6A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability7
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer7
Meet the Associate Editorial Board Member7
Meet the Editorial Board Member7
Meet the Editorial Board Member7
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents7
Novel 4-chloro-N-phenyl Benzamide Derivatives as p38α Mitogenactivated Protein Kinase Inhibitors for Treating Cancer, COVID-19, and Other Diseases7
Patent Selections6
Patent Selections6
Patent Selections6
Effect of Oral Posaconazole on Venetoclax Plasma Concentration and its Efficacy in Patients with Acute Myeloid Leukemia6
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis6
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-Antigen Transfection6
Puerarin: An Anticancer and Anti-Inflammatory Agent6
Comprehensive Bioinformatic Analysis Reveals an Autophagy-related Gene Signature for Predicting Outcome, Immune Status, and Drug Sensitivity in Hepatocellular Carcinoma6
Structure-Based Virtual Screening Identifying Novel FOXM1 Inhibitors as the Lead Compounds for Glioblastoma6
Epigallocatechin Gallate Derivative Y6 Reverses Oxaliplatin Resistance in Hepatocellular Carcinoma via Targeting the MiR-338-3p/HIF-1α/TWIST Axis to Inhibit EMT6
Pulmonary Adenocarcinoma Patient with Complex Mutations on EGFR Benefits from Furmonertinib after Acquiring Gefitinib Resistance: A Case Report6
Protective Assessment of Novel (Bncs Formulation) against Brain Tumor6
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review6
West African Medicinal Plant Substances and Molecules Activities Against Viral Hepatitis B and Hepatocellular Carcinoma5
Patent Selections5
Patent Selections5
Organosulfur Compounds in Garlic for Gastric Cancer Treatment: Anticancer Effects, Overcoming Drug Resistance, and Mechanisms5
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates5
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective5
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding5
Increased SLC7A3 Expression Inhibits Tumor Cell Proliferation and Predicts a Favorable Prognosis in Breast Cancer5
Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer4
Phytochemicals and Nanoparticles in the Modulation of PI3K/Akt/mTOR Kinases and its Implications in the Development and Progression of Gastrointestinal Cancers: A Review of Preclinical and Clinical Ev4
Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin4
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)4
Examining the Mechanisms of Huachansu Injection on Liver Cancer through Integrated Bioinformatics Analysis4
Preclinical Effects of Melatonin on the Development of Ehrlich's Tumor: A Biochemical, Cognitive, and Molecular Approach4
Exosome-Derived Cargos in Immune Microenvironment in Esophageal Carcinoma: A Mini-Review4
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review4
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)4
Ribosome-inactivating Protein MAP30 Isolated from Momordica Charantia L. Induces Apoptosis in Hepatocellular Carcinoma Cells4
Inhibiting the Activity of ABCG2 by KU55933 in Colorectal Cancer4
Understanding and Targeting the Epigenetic Regulation to Overcome EGFR-TKIs Resistance in Human Cancer4
Construction and Validation of a Nomogram for Predicting Progression- Free Survival in Patients with Early-Stage Testicular Germ Cell Tumor4
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells4
Patent Selections3
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism3
Preface3
Natural Product as Substrates of ABC Transporters: A Review3
The Non-hodgkin Lymphoma Treatment and Side Effects: A Systematic Review and Meta-analysis3
Recent Progress in Natural Anticancer Agents Discovery from Tea (Camellia sinensis): A Review3
Identification of Breast Cancer Immune-related Prognostic Characteristics in Tumor Microenvironment3
The Anti-Tumor Mechanism and Target of Triptolide Based on Network Pharmacology and Molecular Docking3
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways3
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment3
The Prognostic and Drug-targeting Value of Lymphoid Enhancer-binding Factor-1 in Hepatocellular Carcinoma3
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model3
Novel Pathways and Mechanisms of Nicotine-Induced Oral Carcinogenesis3
Causal Relationships of Chronic Constipation and Irritable Bowel Syndrome with Digestive Tract Cancers: A Mendelian Randomization Study3
Patent Selections3
Repurposing Chloroquine Analogs as an Adjuvant Cancer Therapy3
Targeting Ferroptosis as a New Approach for Radiation Protection and Mitigation3
The Anti-Proliferative Effect of a Newly-Produced Anti-PSCA-Peptide Antibody by Multiple Bioinformatics Tools, on Prostate Cancer Cells3
Circ_0070203 Promotes Epithelial-mesenchymal Transition in Ovarian Serous Cystadenocarcinoma through miR-370-3p/TGFβR2 Axis3
Pseudo-ginsenoside Rh2 Induces Protective Autophagy in Hepatocellular Carcinoma HepG2 Cells3
A Link Between Chemical Structure and Biological Activity in Triterpenoids3
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment3
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer2
The Patent Landscape of BRAF Target and KRAS Target2
Preface2
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 2
Sema3A Inhibits Osteolytic Bone Metastasis of Non-small Cell Lung Cancer2
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present2
Strategies for Developing Cancer Theranostics Approaches2
TENT5A Increases Glioma Malignancy and Promotes its Progression2
Identification of Immune Infiltration-related Molecular Features in Ovarian Cancer Patients and Experimental Validation of Immune Response Molecular Mechanisms through Integrated WGCNA, Machine Learni2
Eukaryotic Initiation Factor 3C Can Affect the Proliferation and Invasion of Ovarian Cancer by Regulating the p53 Signalling Pathway2
Antibody-drug Conjugates for Breast Cancer Treatment2
A Three-agent Regimen for Triple Negative Breast Cancer Treatment2
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies2
Altering Landscape of Cancer Vaccines: Unique Platforms, Research on Therapeutic Applications and Recent Patents2
Induced Fit Docking and Automated QSAR Studies Reveal the ER-α Inhibitory Activity of Cannabis sativa in Breast Cancer2
The Clinical Significance and Prognostic Value of ALDH1 Expression in Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis2
Next Generation Sequencing in the Management of Leptomeningeal Metastases of Non-Small Cell Lung Cancer: A Case Report and Literature Review2
Research and Patents Status of Selected Phytochemicals Against Cancer: How Close and How Far?2
Clinical CDK2 Inhibitors: Trends to Selectivity and Efficacy1
Patent Selections1
Meet the Associate Editor1
Ruthenium Complex Suppresses Proliferation of Residual Hepatocellular Carcinoma after Incomplete Radiofrequency Ablation Therapy1
Meet the Editorial Board Member1
Neochamaejasmine A Promotes Apoptosis and Cell Cycle Arrest in B16F10 Melanoma Cells via JNK and p38 MAPK Signaling Pathway1
Metformin Inhibits NLRP3 Inflammasome Expression and Regulates Inflammatory Microenvironment to Delay the Progression of Colorectal Cancer1
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways1
Stem Cell Markers in Neoplasms and their Relationship with Progression-free and Overall Survival in Patients with Recurrence1
Recent Patent-Based Perspective on Diagnostic and Therapeutic Interventions in Malignant Mesothelioma: Is Drug Repositioning Knocking on the Door?1
Current Status and Future Perspectives on Old Drug Repurposing for Cancer Treatment1
Expression and Clinical Significance of Microtubule-Actin Cross-Linking Factor 1 in Serous Ovarian Cancer1
Potential Therapeutic Targets of Curcumin, Most Abundant Active Compound of Turmeric Spice: Role in the Management of Various Types of Cancer1
Selinexor as a Therapeutic Target: Advances in Non-small Cell and Small Cell Lung Cancer Treatment Strategies1
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years1
Meet the Associate Editor1
Multifunctional Patented Nanotherapeutics for Cancer Intervention: 2010- Onwards1
Withdrawn: Fumarate-1 Mediates the Regulation of Mitochondrial Homeostasis by PGC-1α to Promote Cell Pyroptosis and Inhibit the Thyroid Cancer1
From Multiple Myeloma to Acute Myeloid Leukemia: A Case Report of a 61-year-old Woman after 8 Years of Chemotherapy and Immunotherapy1
Matrine Enhances the Antitumor Efficacy of Chidamide in CTCL by Promoting Apoptosis1
Meet the Editorial Board Member1
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