Recent Patents on Anti-Cancer Drug Discovery

Papers
(The median citation count of Recent Patents on Anti-Cancer Drug Discovery is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Acknowledgement to Contributors39
Acknowledgement to Reviewers23
Interplay between RNA Methylation Eraser FTO and Writer METTL3 in Renal Clear Cell Carcinoma Patient Survival23
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progression of Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway22
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies18
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer17
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy16
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration15
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates15
Research Progress on the Anticancer Activity of Plant Polysaccharides15
Patent Selections15
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer15
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer14
Protective Assessment of Novel (BNC Formulation) against Brain Tumor14
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review14
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review14
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)13
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma with Radiotherapy Interruptions: A Lesson Learned from the Lockdown Due to COVID-1913
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents13
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment13
The Anti-Tumor Mechanism and Target of Triptolide Based on Network Pharmacology and Molecular Docking13
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment12
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer12
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer12
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway11
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration11
Acknowledgement To Reviewers11
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches11
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment10
STAT3 Inhibitor Napabucasin Inhibits Tumor Growth and Cooperates with Proteasome Inhibition in Human Ovarian Cancer Cells10
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer10
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma10
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells10
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study9
Patent Selections9
Bourgeoning Cancer Targets9
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database9
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis9
Antioxidant, Anti-Inflammatory and Anticancer Activities of the Methanolic Extract of Thottea siliquosa: An In Vitro and In Silico Study9
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms9
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review8
Recent Trend for EGFR-Based and ALK-Based Targets: A Patent Analysis8
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells8
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing8
Patent Selections8
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding8
The m6A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability8
Current Status and Prospects of Camrelizumab, A Humanized Antibody Against Programmed Cell Death Receptor 18
Puerarin: An Anticancer and Anti-Inflammatory Agent8
Meet the Editorial Board Member8
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism7
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review7
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis7
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective7
Patent Selections7
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)7
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions7
Preface7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years6
Investigating the Therapeutic Potential and Molecular Mechanisms of Daphnetin: A Comprehensive Review6
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model6
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression6
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury6
Advances in the Treatment of Chronic Myeloid Leukemia6
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer6
Patent Selections6
Morusin Suppresses Pancreatic Cancer Cell Proliferation and Migration by Targeting SLC6A12 to Inhibit NF-κB and β-catenin Signaling Pathways5
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma5
Exosome-Derived Cargos in Immune Microenvironment in Esophageal Carcinoma: A Mini-Review5
Patent Selections5
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer5
KRAS Pathways: A Potential Gateway for Cancer Therapeutics and Diagnostics5
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA35
Ribosome-inactivating Protein MAP30 Isolated from Momordica Charantia L. Induces Apoptosis in Hepatocellular Carcinoma Cells5
Antibody-drug Conjugates for Breast Cancer Treatment5
Patent Selections5
Targeting Notch Pathway in Cancer Diagnostics and Therapeutics: An Emerging Approach5
Development of a Novel Lipid Metabolism-related Gene Prognostic Signature for Patients with Colorectal Cancer5
Strategies for Developing Cancer Theranostics Approaches5
Epigallocatechin Gallate Derivative Y6 Reverses Oxaliplatin Resistance in Hepatocellular Carcinoma via Targeting the MiR-338-3p/HIF-1α/TWIST Axis to Inhibit EMT5
Altering Landscape of Cancer Vaccines: Unique Platforms, Research on Therapeutic Applications and Recent Patents4
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies4
Meet the Editorial Board Member4
Identification of Breast Cancer Immune-related Prognostic Characteristics in Tumor Microenvironment4
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways4
Differentiation of Acute Leukemia Cells Including Cells with MLL-AF4 Rearrangements Induced by Jiyuan Oridonin A4
Targeting Ferroptosis as a New Approach for Radiation Protection and Mitigation4
β-estradiol Induces Mitochondrial Apoptosis in Cervical Cancer through the Suppression of AKT/NF-κB Signaling Pathway4
Meet the Associate Editorial Board Member3
Patent Selections3
Patent Selections3
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review3
Nanotechnology a Boon for Colorectal Cancer Treatment3
The Role of KCNMA1 Expression in Digestive Cancers: A Potential Prognostic Biomarker3
Human Saliva Metabolome for Oral Lichen Planus Biomarker Identification3
Recent Patents of Pharmaceutical Co-Crystals: Product Development on Anti-Cancer Drugs and Beyond3
Green Synthesized Nanoparticles as a Plausible Therapeutic Strategy Against Hepatocellular Carcinoma: An Update on its Preclinical and Clinical Relevance3
Competitive Effect of Overexpressed C-terminal of Snail-1 (CSnail) in Control of the Growth and Metastasis of Melanoma Cells3
Adhesin Component Member STAG2 Enhances Cisplatin Tolerance in Colorectal Cancer Cells through the Epithelial-Mesenchymal Transition Pathway3
New 1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-phenylisoquinoline-1(2H)-ones as Phosphoinositide 3-kinase Inhibitors for Treating Cancer and Other Diseases3
The Impact of Polyphenolics in the Management of Breast Cancer: Mechanistic Aspects and Recent Patents3
Updated Progress on Mass Spectrometry Imaging and its Application in Cancer Treatment and Drug Discovery2
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway2
Increased SLC7A3 Expression Inhibits Tumor Cell Proliferation and Predicts a Favorable Prognosis in Breast Cancer2
Inhibiting the Activity of ABCG2 by KU55933 in Colorectal Cancer2
Metal Nanoparticles as Emerging Drug Candidates in the Management of Cancers and Microbial Infectious Diseases2
Patent Selections2
Development and Evaluation of a Novel Hyaluronic Acid and Chitosan-modified Phytosome for Co-delivery of Oxymatrine and Glycyrrhizin for Combination Therapy2
1,3,4-Oxadiazoles as Anticancer Agents: A Review2
Dahuang Zhechong Pill Combined with TNS4 Silencing Inhibits the NF-Κb/VEGF Pathway To Slow Down The Progression Of Pancreatic Cancer2
Identification of Immune Infiltration-related Molecular Features in Ovarian Cancer Patients and Experimental Validation of Immune Response Molecular Mechanisms through Integrated WGCNA, Machine Learni2
West African Medicinal Plant Substances and Molecules Activities Against Viral Hepatitis B and Hepatocellular Carcinoma2
Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer2
Unveiling miR-1468-5p: A New Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma2
A Combined Bioinformatic and Nanoparticle-Based Study Reveal the Role of ABCG2 in the Drug Resistant Breast Cancer2
Transdermal Drug Delivery: A Step towards Treatment of Cancer2
Preclinical Effects of Melatonin on the Development of Ehrlich's Tumor: A Biochemical, Cognitive, and Molecular Approach2
Phytochemicals and Nanoparticles in the Modulation of PI3K/Akt/mTOR Kinases and its Implications in the Development and Progression of Gastrointestinal Cancers: A Review of Preclinical and Clinical Ev2
The Patent Landscape of BRAF Target and KRAS Target2
0.069734811782837