Recent Patents on Anti-Cancer Drug Discovery

Papers
(The median citation count of Recent Patents on Anti-Cancer Drug Discovery is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
Acknowledgement to Contributors36
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy22
Acknowledgement to Reviewers22
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies20
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer16
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer16
Research Progress on the Anticancer Activity of Plant Polysaccharides15
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration15
Patent Selections15
Interplay between RNA Methylation Eraser FTO and Writer METTL3 in Renal Clear Cell Carcinoma Patient Survival15
The Anti-Tumor Mechanism and Target of Triptolide Based on Network Pharmacology and Molecular Docking14
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates14
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)14
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents13
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer13
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review13
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer13
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment13
Acknowledgement To Reviewers12
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway12
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration11
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches11
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms10
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma10
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis10
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment10
Bourgeoning Cancer Targets10
STAT3 Inhibitor Napabucasin Inhibits Tumor Growth and Cooperates with Proteasome Inhibition in Human Ovarian Cancer Cells10
Antioxidant, Anti-Inflammatory and Anticancer Activities of the Methanolic Extract of Thottea siliquosa: An In Vitro and In Silico Study9
Recent Trend for EGFR-Based and ALK-Based Targets: A Patent Analysis9
Patent Selections9
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database9
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-Antigen Transfection8
Patent Selections8
Meet the Editorial Board Member8
The m6A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability8
Current Status and Prospects of Camrelizumab, A Humanized Antibody Against Programmed Cell Death Receptor 18
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding8
Puerarin: An Anticancer and Anti-Inflammatory Agent8
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review8
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis7
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Patent Selections7
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells7
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)7
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways7
Preface7
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism7
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
KRAS Pathways: A Potential Gateway for Cancer Therapeutics and Diagnostics6
Development of a Novel Lipid Metabolism-related Gene Prognostic Signature for Patients with Colorectal Cancer6
Patent Selections6
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present6
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years6
Investigating the Therapeutic Potential and Molecular Mechanisms of Daphnetin: A Comprehensive Review6
Patent Selections6
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression6
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer6
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer6
Targeting Notch Pathway in Cancer Diagnostics and Therapeutics: An Emerging Approach6
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model6
Advances in the Treatment of Chronic Myeloid Leukemia6
Patents on PARP-1 Inhibitors for the Management of Cancer from 2017-20235
Epigallocatechin Gallate Derivative Y6 Reverses Oxaliplatin Resistance in Hepatocellular Carcinoma via Targeting the MiR-338-3p/HIF-1α/TWIST Axis to Inhibit EMT5
Strategies for Developing Cancer Theranostics Approaches5
Exosome-Derived Cargos in Immune Microenvironment in Esophageal Carcinoma: A Mini-Review5
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA35
Ribosome-inactivating Protein MAP30 Isolated from Momordica Charantia L. Induces Apoptosis in Hepatocellular Carcinoma Cells5
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies5
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma5
Structure-Based Virtual Screening Identifying Novel FOXM1 Inhibitors as the Lead Compounds for Glioblastoma5
Antibody-drug Conjugates for Breast Cancer Treatment5
Patent Selections5
ZFP36L1 Promotes Gastric Cancer Progression via Regulating JNK and p38 MAPK Signaling Pathways4
Differentiation of Acute Leukemia Cells Including Cells with MLL-AF4 Rearrangements Induced by Jiyuan Oridonin A4
New 1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-phenylisoquinoline-1(2H)-ones as Phosphoinositide 3-kinase Inhibitors for Treating Cancer and Other Diseases4
Targeting Ferroptosis as a New Approach for Radiation Protection and Mitigation4
Altering Landscape of Cancer Vaccines: Unique Platforms, Research on Therapeutic Applications and Recent Patents4
β-estradiol Induces Mitochondrial Apoptosis in Cervical Cancer through the Suppression of AKT/NF-κB Signaling Pathway4
Patent Selections4
Eukaryotic Initiation Factor 3C Can Affect the Proliferation and Invasion of Ovarian Cancer by Regulating the p53 Signalling Pathway4
Meet the Editorial Board Member4
Human Saliva Metabolome for Oral Lichen Planus Biomarker Identification4
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review3
Meet the Associate Editorial Board Member3
1,3,4-Oxadiazoles as Anticancer Agents: A Review3
A Combined Bioinformatic and Nanoparticle-Based Study Reveal the Role of ABCG2 in the Drug Resistant Breast Cancer3
A Single-Arm, Open-Label, Phase Ib Clinical Study Evaluating the Efficacy and Safety of Durvalumab in Combination with Albumin-Bound Paclitaxel and Carboplatin as Neoadjuvant Therapy for Resectable St3
Adhesin Component Member STAG2 Enhances Cisplatin Tolerance in Colorectal Cancer Cells through the Epithelial-Mesenchymal Transition Pathway3
Nanotechnology a Boon for Colorectal Cancer Treatment3
Patent Selections3
Recent Patents of Pharmaceutical Co-Crystals: Product Development on Anti-Cancer Drugs and Beyond3
Green Synthesized Nanoparticles as a Plausible Therapeutic Strategy Against Hepatocellular Carcinoma: An Update on its Preclinical and Clinical Relevance3
Competitive Effect of Overexpressed C-terminal of Snail-1 (CSnail) in Control of the Growth and Metastasis of Melanoma Cells3
The Role of KCNMA1 Expression in Digestive Cancers: A Potential Prognostic Biomarker3
The Impact of Polyphenolics in the Management of Breast Cancer: Mechanistic Aspects and Recent Patents3
Preclinical Effects of Melatonin on the Development of Ehrlich's Tumor: A Biochemical, Cognitive, and Molecular Approach2
Transdermal Drug Delivery: A Step towards Treatment of Cancer2
Metal Nanoparticles as Emerging Drug Candidates in the Management of Cancers and Microbial Infectious Diseases2
TENT5A Increases Glioma Malignancy and Promotes its Progression2
The Non-hodgkin Lymphoma Treatment and Side Effects: A Systematic Review and Meta-analysis2
Identification of Immune Infiltration-related Molecular Features in Ovarian Cancer Patients and Experimental Validation of Immune Response Molecular Mechanisms through Integrated WGCNA, Machine Learni2
Development and Evaluation of a Novel Hyaluronic Acid and Chitosan-modified Phytosome for Co-delivery of Oxymatrine and Glycyrrhizin for Combination Therapy2
Increased SLC7A3 Expression Inhibits Tumor Cell Proliferation and Predicts a Favorable Prognosis in Breast Cancer2
Nano-Based Drug Delivery of Anticancer Chemotherapeutic Drugs Targeting Breast Cancer2
Phytochemicals and Nanoparticles in the Modulation of PI3K/Akt/mTOR Kinases and its Implications in the Development and Progression of Gastrointestinal Cancers: A Review of Preclinical and Clinical Ev2
The Patent Landscape of BRAF Target and KRAS Target2
Inhibiting the Activity of ABCG2 by KU55933 in Colorectal Cancer2
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway2
Patent Selections2
West African Medicinal Plant Substances and Molecules Activities Against Viral Hepatitis B and Hepatocellular Carcinoma2
Pseudo-ginsenoside Rh2 Induces Protective Autophagy in Hepatocellular Carcinoma HepG2 Cells2
Sema3A Inhibits Osteolytic Bone Metastasis of Non-small Cell Lung Cancer2
Neochamaejasmine A Promotes Apoptosis and Cell Cycle Arrest in B16F10 Melanoma Cells via JNK and p38 MAPK Signaling Pathway1
B-9-8, a Novel Harman Dimer, Reverses ABCG2-mediated Chemotherapeutic Drug Resistance1
Development and Validation of a Hypoxia-related Prognostic Model for Ovarian Cancer1
The ER Stress-related Gene Prognostic Signature for Predicting Chemosensitivity and Prognosis in AML1
PDLIM1 Inhibits Chemoresistance by Blocking DNA Damage Repair in Gastric Cancer1
Knockdown of RhoA Expression Reverts Enzalutamide Resistance via the p38 MAPK Pathway in Castration-resistant Prostate Cancer1
A Link Between Chemical Structure and Biological Activity in Triterpenoids1
From Multiple Myeloma to Acute Myeloid Leukemia: A Case Report of a 61-year-old Woman after 8 Years of Chemotherapy and Immunotherapy1
Acknowledgements to Contributor1
Differential Expression and Distribution of Slco4a1 and Slco1b2 in an Internal Environment Disorder-induced Hepatocellular Carcinoma Mouse Model1
The Validity of Mobile Applications to Facilitate Patient Care Provided to Cancer Patients: Opportunities and Limitations1
Acknowledgements to Reviewer1
Withdrawn: Fumarate-1 Mediates the Regulation of Mitochondrial Homeostasis by PGC-1α to Promote Cell Pyroptosis and Inhibit the Thyroid Cancer1
Selinexor as a Therapeutic Target: Advances in Non-small Cell and Small Cell Lung Cancer Treatment Strategies1
The Clinical Significance and Prognostic Value of ALDH1 Expression in Non-small Cell Lung Cancer: A Systematic Review and Meta-analysis1
Gefitinib: An Updated Review of its Role in the Cancer Management, its Nanotechnological Interventions, Recent Patents and Clinical Trials1
PSMA PET/MR is a New Imaging Option for Identifying Glioma Recurrence and Predicting Prognosis1
Characterization of the Prognosis and Tumor Microenvironment of Cellular Senescence-related Genes through scRNA-seq and Bulk RNA-seq Analysis in GC1
The Synergistic Anti-tumor Effects of Evodiamine based on Animal Model Experiments: A Systematic Review and Meta-analysis1
Patent Selections1
LncRNA FAM83H-AS1 Contributes to the Radio-resistance and Proliferation in Liver Cancer through Stability FAM83H Protein1
A Descriptive Review of Cannabis sativa Patents for Cancer Treatment1
Recent Progress in Natural Anticancer Agents Discovery from Tea (Camellia sinensis): A Review1
Prediction of Cancer Treatment Using Advancements in Machine Learning1
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