Recent Patents on Anti-Cancer Drug Discovery

Papers
(The TQCC of Recent Patents on Anti-Cancer Drug Discovery is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Acknowledgement to Contributors47
Acknowledgement to Reviewers28
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies26
Research Progress on the Anticancer Activity of Plant Polysaccharides24
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy22
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer20
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progressionof Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway19
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration18
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review16
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review16
Patent Selections16
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)15
Protective Assessment of Novel (BNC Formulation) against Brain Tumor15
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents15
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer15
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment14
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment14
The Prognostic Role of Interferon Gamma-inducible Protein 30 in ClearCell Renal Cell Carcinoma with Immune Infiltrates14
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer13
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma withRadiotherapy Interruptions: A Lesson Learned from the Lockdown Due toCOVID-1913
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer13
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway13
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment11
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer11
Vitexin's Role in Colon Cancer Apoptosis: AMPK/mTOR PathwayModulation Explored Through Experimental and ComputationalApproaches11
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells11
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma11
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration11
Acknowledgement To Reviewers11
Patent Selections10
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis10
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review10
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding10
Bourgeoning Cancer Targets10
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms10
Patent Selections10
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing10
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study10
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database10
Meet the Editorial Board Member10
Puerarin: An Anticancer and Anti-Inflammatory Agent9
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-antigen Transfection9
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis9
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways9
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism9
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells8
The m 6 A Reader IGF2BP2 Promotes Oral Squamous Cell CarcinomaProgression by Maintaining UCA1 Stability8
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective8
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)8
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions8
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review8
Preface7
Aucubin Inhibits Liver Cancer via HMGB1-mediated Inactivation of the PI3K/AKT/mTOR Signaling Pathway7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years7
Patent Selections7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model7
Advances in the Treatment of Chronic Myeloid Leukemia7
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression7
Investigating the Therapeutic Potential and Molecular Mechanisms ofDaphnetin: A Comprehensive Review6
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury6
Patent Selections6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer6
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