Recent Patents on Anti-Cancer Drug Discovery

Papers
(The TQCC of Recent Patents on Anti-Cancer Drug Discovery is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Quercetin Promotes the M1-to-M2 Macrophage Phenotypic Switch During Liver Fibrosis Treatment by Modulating the JAK2/STAT3 Signaling Pathway32
Patent Selections25
Research Progress on the Anticancer Activity of Plant Polysaccharides25
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review21
Acknowledgement to Reviewers20
Acknowledgement to Contributors20
Overview of Inorganic Nanoparticles: An Expanding Horizon in Tumor Therapeutics16
Patent Selections:16
Interplay between RNA Methylation Eraser FTO and Writer METTL3 in Renal Clear Cell Carcinoma Patient Survival15
Fat-soluble Vitamins and Lung Cancer: Where We Are?15
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma Based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing14
The Influence of Wuzhi Capsule on the Pharmacokinetics of Cyclophosphamide13
Daidzein and Chicory Extract Arrest the Cell Cycle via Inhibition of Cyclin D/CDK4 and Cyclin A/CDK2 Gene Expression in Hepatocellular Carcinoma13
Recent Patents on Plant-Derived Nanoparticles and their Potential Application Towards Various Cancer Therapeutics13
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database13
Covalent Inhibitor Screening for Targeting LOXL2: Studied by Virtual Screening and Experimental Validation13
Patents on PARP-1 Inhibitors for the Management of Cancer from 2017-202312
Upregulation of M6A Reader HNRNPA2B1 Associated with Poor Prognosis and Tumor Progression in Lung Adenocarcinoma12
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer12
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies12
Current Status and Prospects of Camrelizumab, A Humanized Antibody Against Programmed Cell Death Receptor 112
NIFK, a Potential Prognostic and Immunological Biomarker in Pan-- Cancer Analysis, Significantly Regulates Proliferation and Metastasis of Colorectal Cancer12
Distinct Epigenetic Reprogramming, Mitochondrial Patterns, Cellular Morphology, and Cytotoxicity after Bee Venom Treatment11
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy11
Antioxidant, Anti-Inflammatory and Anticancer Activities of the Methanolic Extract of Thottea siliquosa: An In Vitro and In Silico Study11
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer11
Repurposing of Metformin for Cancer Therapy: Updated Patent and Literature Review10
Human Chorionic Gonadotropin Regulates the Smad Signaling Pathway by Antagonizing TGF-β in Giant Cell Tumor of Bone10
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration10
Development and Evaluation of a Novel Hyaluronic Acid and Chitosan-modified Phytosome for Co-delivery of Oxymatrine and Glycyrrhizin for Combination Therapy9
An Update of Lysine Specific Demethylase 1 Inhibitor: A Patent Review (2016-2020)9
Recent Trend for EGFR-Based and ALK-Based Targets: A Patent Analysis9
Anti-HER2 VHH Targeted Fluorescent Liposome as Bimodal Nanoparticle for Drug Delivery and Optical Imaging9
Regression of Breast Cancer Metastases Following Treatment with Irradiated SV-BR-1-GM, a GM-CSF Overexpressing Breast Cancer Cell Line: Intellectual Property and Immune Markers of Response8
Patent Selections8
Tyrosine Kinase Inhibitor Lenvatinib Causes Cardiotoxicity by Inducing Endoplasmic Reticulum Stress and Apoptosis through Activating ATF6, IRE1α and PERK Signaling Pathways8
Anti-EGFR-mAb and 5-Fluorouracil Conjugated Polymeric Nanoparticles for Colorectal Cancer8
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions8
Transdermal Drug Delivery: A Step towards Treatment of Cancer8
LINC00936/microRNA-221-3p Regulates Tumor Progression in Ovarian Cancer by Interacting with LAMA38
Downregulation of miRNA-14669 Reverses Vincristine Resistance in Colorectal Cancer Cells through PI3K/AKT Signaling Pathway8
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta- Analysis and Systematic Review7
The m6A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability7
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer7
Meet the Associate Editorial Board Member7
Meet the Editorial Board Member7
Meet the Editorial Board Member7
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents7
Novel 4-chloro-N-phenyl Benzamide Derivatives as p38α Mitogenactivated Protein Kinase Inhibitors for Treating Cancer, COVID-19, and Other Diseases7
Metal Nanoparticles as Emerging Drug Candidates in the Management of Cancers and Microbial Infectious Diseases7
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis6
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-Antigen Transfection6
Puerarin: An Anticancer and Anti-Inflammatory Agent6
Comprehensive Bioinformatic Analysis Reveals an Autophagy-related Gene Signature for Predicting Outcome, Immune Status, and Drug Sensitivity in Hepatocellular Carcinoma6
Structure-Based Virtual Screening Identifying Novel FOXM1 Inhibitors as the Lead Compounds for Glioblastoma6
Epigallocatechin Gallate Derivative Y6 Reverses Oxaliplatin Resistance in Hepatocellular Carcinoma via Targeting the MiR-338-3p/HIF-1α/TWIST Axis to Inhibit EMT6
Pulmonary Adenocarcinoma Patient with Complex Mutations on EGFR Benefits from Furmonertinib after Acquiring Gefitinib Resistance: A Case Report6
Protective Assessment of Novel (Bncs Formulation) against Brain Tumor6
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review6
Patent Selections6
Patent Selections6
Patent Selections6
Effect of Oral Posaconazole on Venetoclax Plasma Concentration and its Efficacy in Patients with Acute Myeloid Leukemia6
Patent Selections5
Organosulfur Compounds in Garlic for Gastric Cancer Treatment: Anticancer Effects, Overcoming Drug Resistance, and Mechanisms5
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates5
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective5
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding5
Increased SLC7A3 Expression Inhibits Tumor Cell Proliferation and Predicts a Favorable Prognosis in Breast Cancer5
West African Medicinal Plant Substances and Molecules Activities Against Viral Hepatitis B and Hepatocellular Carcinoma5
Patent Selections5
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