Recent Patents on Anti-Cancer Drug Discovery

Papers
(The TQCC of Recent Patents on Anti-Cancer Drug Discovery is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Acknowledgement to Contributors41
Acknowledgement to Reviewers25
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progression of Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway22
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer18
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy17
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies17
Research Progress on the Anticancer Activity of Plant Polysaccharides16
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration16
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates15
Patent Selections15
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer14
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents14
Protective Assessment of Novel (BNC Formulation) against Brain Tumor14
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review14
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)14
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma with Radiotherapy Interruptions: A Lesson Learned from the Lockdown Due to COVID-1913
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment13
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment13
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review13
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer12
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway12
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer12
Acknowledgement To Reviewers11
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration11
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma10
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment10
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells10
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches10
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer10
Bourgeoning Cancer Targets9
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study9
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing9
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms9
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database9
Patent Selections9
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis9
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review9
Patent Selections8
Meet the Editorial Board Member8
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism8
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective8
The m6A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability8
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells8
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review8
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways8
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding8
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis8
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions8
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)8
Puerarin: An Anticancer and Anti-Inflammatory Agent7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
Preface7
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-antigen Transfection7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression6
Advances in the Treatment of Chronic Myeloid Leukemia6
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer6
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer6
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model6
Patent Selections6
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years6
Investigating the Therapeutic Potential and Molecular Mechanisms of Daphnetin: A Comprehensive Review6
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