Recent Patents on Anti-Cancer Drug Discovery

Papers
(The TQCC of Recent Patents on Anti-Cancer Drug Discovery is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Acknowledgement to Contributors59
Acknowledgement to Reviewers53
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy35
ZNF146-Mediated HMGB1-NF-κB Signaling Activation as a Therapeutic Target and Prognostic Biomarker in Osteosarcoma33
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration21
Research Progress on the Anticancer Activity of Plant Polysaccharides20
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progression of Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway18
Patent Selections17
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies17
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer17
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents15
Protective Assessment of Novel (BNC Formulation) against Brain Tumor15
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates15
Multi-omics Analysis Uncovers TFRC/HMOX1-dependent Ferroptosis Mediating Celastrol’s Anti-invasive/Metastatic Effects on Esophageal Squamous Cell Carcinoma15
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment14
A Comprehensive Review of Genistein and Chitosan: Mechanistic Foundations, Regulatory Roadmap, and Future Research Directions14
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment14
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review14
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review14
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer13
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway13
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma with Radiotherapy Interruptions: A Lesson Learned from the Lockdown Due to COVID-1913
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer13
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer13
Acknowledgement To Reviewers13
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells12
Patent Selections12
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration12
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches12
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma11
Bourgeoning Cancer Targets11
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis11
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database10
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing10
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review10
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms10
Mir-338-3p Increases the Sensitivity to Oxaliplatin via Reversing Epithelialmesenchymal Transition in Hepatocellular Carcinoma Cells10
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study10
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding9
Meet the Editorial Board Member9
Patent Selections9
Puerarin: An Anticancer and Anti-Inflammatory Agent8
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism8
The m 6 A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability8
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis8
Acknowledgement to Reviewers8
Construction and Identification of a Human Colorectal Adenoma Epithelial Cell Line by SV40 Large T-antigen Transfection8
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways7
Preface7
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective7
Aucubin Inhibits Liver Cancer via HMGB1-mediated Inactivation of the PI3K/AKT/mTOR Signaling Pathway7
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review7
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions7
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present6
Prognostic and Therapeutic Values of Autophagy-related Genes in Triple-negative Breast Cancer6
Advances in the Treatment of Chronic Myeloid Leukemia6
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model6
Exploring the Anticancer Potentials of Polyphenols: A Comprehensive Review of Patents in the Last Five Years6
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer6
Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model6
Patent Selections5
A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury5
Investigating the Therapeutic Potential and Molecular Mechanisms ofDaphnetin: A Comprehensive Review5
Morusin Suppresses Pancreatic Cancer Cell Proliferation and Migration by Targeting SLC6A12 to Inhibit NF-κB and β-catenin Signaling Pathways5
LMNB1 and LMNB2 as Prognostic Risk Factors in Hepatocellular Carcinoma: Therapeutic Potential of GSK461364 via Downregulation of LMNB1 and LMNB2 Expression5
UBE2L3 Suppresses Oxidative Stress-regulated Necroptosis to Accelerate Osteosarcoma Progression5
Advancements in Sotorasib: A Comprehensive Review of its Efficacy in Non-small Lung Cancer Treatment5
Patent Selections5
KRAS Pathways: A Potential Gateway for Cancer Therapeutics and Diagnostics5
Patents on PARP-1 Inhibitors for the Management of Cancer from 2017-20235
pH-responsive Sulfated Hyaluronic Acid Nanoparticles Targeting Tumor Cells and CAFs for the Treatment of Breast Cancer5
Melanoma Metastasizing to the Breast: A Case Report5
Nano-carriers based Approaches Loaded with Herbal Bioactive Compounds for the Treatment of Cancer: Recent Updates and Future Prospects5
Targeting Notch Pathway in Cancer Diagnostics and Therapeutics: An Emerging Approach5
Development of a Novel Lipid Metabolism-related Gene Prognostic Signature for Patients with Colorectal Cancer5
1.018935918808