Recent Patents on Anti-Cancer Drug Discovery

Papers
(The TQCC of Recent Patents on Anti-Cancer Drug Discovery is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Acknowledgement to Contributors39
Interplay between RNA Methylation Eraser FTO and Writer METTL3 in Renal Clear Cell Carcinoma Patient Survival23
Acknowledgement to Reviewers23
L-Selenomethylselenocysteine Exerts Inhibitory Effects on the Progression of Esophageal Cancer by Targeting the PI3K/AKT Signaling Pathway22
Advanced Strategies of CAR-T Cell Therapy in Solid Tumors and Hematological Malignancies18
High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer17
Current Prospects for Adrenocortical Carcinoma Pharmacotherapy16
Patent Selections15
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer15
Comprehensive Genomic Analysis of Puerarin in Inhibiting Bladder Urothelial Carcinoma Cell Proliferation and Migration15
The Prognostic Role of Interferon Gamma-inducible Protein 30 in Clear Cell Renal Cell Carcinoma with Immune Infiltrates15
Research Progress on the Anticancer Activity of Plant Polysaccharides15
Statin Use and Hepatocellular Carcinoma Risk: A Comprehensive Meta-Analysis and Systematic Review14
Bioinformatic Analysis and Experimental Validation of HMGA2-AS1 as a Prognostic Biomarker Associated with Immune Infiltration in Gastric Cancer14
Protective Assessment of Novel (BNC Formulation) against Brain Tumor14
Radiotherapy Enhancing and Radioprotective Properties of Berberine: A Systematic Review14
The Present State and Potential Applications of Artificial Intelligence in Cancer Diagnosis and Treatment13
The Anti-Tumor Mechanism and Target of Triptolide Based on Network Pharmacology and Molecular Docking13
Santacruzamate A Compositions, Analogs and Methods of Use: A Patent Evaluation of WO 2014/018913 (A2)13
Oral Metronomic Chemotherapy in Nasopharyngeal Carcinoma with Radiotherapy Interruptions: A Lesson Learned from the Lockdown Due to COVID-1913
Nanomaterials for Diagnosis and Treatment of Lung Cancer: A Review of Recent Patents13
Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer12
The Application of Nanotechnology in Immunotherapy based Combinations for Cancer Treatment12
Network Pharmacology-based Prediction and Verification of Shikonin for Treating Colorectal Cancer12
Vitexin’s Role in Colon Cancer Apoptosis: AMPK/mTOR Pathway Modulation Explored Through Experimental and Computational Approaches11
Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway11
USP31 Activates the Wnt/β-catenin Signaling Pathway and Promotes Gastric Cancer Cell Proliferation, Invasion and Migration11
Acknowledgement To Reviewers11
Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma10
Regulating Lipid Metabolism via Mitochondrial Dynamics in Tongue Squamous Cell Carcinoma Cancer Stem Cells10
Self-immolative Linkers in Prodrugs and Antibody Drug Conjugates in Cancer Treatment10
STAT3 Inhibitor Napabucasin Inhibits Tumor Growth and Cooperates with Proteasome Inhibition in Human Ovarian Cancer Cells10
Bioinformatics Analysis of Key Genes Associated with Resistance to the Combination of Bevacizumab and Pemetrexed Chemotherapy in Non-small Cell Lung Cancer10
Antioxidant, Anti-Inflammatory and Anticancer Activities of the Methanolic Extract of Thottea siliquosa: An In Vitro and In Silico Study9
Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms9
Survival Benefits of Ganoderma Lucidum in Early-stage Triple-negative Breast Cancer: A Real World Study9
Patent Selections9
Bourgeoning Cancer Targets9
Predictive Modelling of Overall Survival in Adult Patients with Primary Diffuse Large B-cell Lymphoma of the Breast Using the Surveillance, Epidemiology, and End Results (SEER) Database9
The Causal Effects of Cholelithiasis on Acute Pancreatitis and Pancreatic Cancer: A Large Sample Size Mendelian Randomization Analysis9
Current Status and Prospects of Camrelizumab, A Humanized Antibody Against Programmed Cell Death Receptor 18
Puerarin: An Anticancer and Anti-Inflammatory Agent8
Meet the Editorial Board Member8
Prospective Challenges for Patenting and Clinical Trials of Anticancer Compounds from Natural Products: Coherent Review8
Recent Trend for EGFR-Based and ALK-Based Targets: A Patent Analysis8
Circular RNA NF1-419 Inhibits Proliferation and Induces Apoptosis by Regulating Lipid Metabolism in Astroglioma Cells8
Screening of Candidate Inflammatory Markers of Epithelial Cells in Hepatocellular Carcinoma based on Integration Analysis of TCGA/ICGC Databases and Single-cell Sequencing8
Patent Selections8
Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding8
The m6A Reader IGF2BP2 Promotes Oral Squamous Cell Carcinoma Progression by Maintaining UCA1 Stability8
Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)7
Targeting the Key Signaling Pathways in Breast Cancer: From Molecular Mechanism to Therapeutic Interventions7
Preface7
The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer7
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism7
Natural STAT3 Inhibitors for Cancer Treatment: A Comprehensive Literature Review7
SSPH I, A Novel Anti-cancer Saponin, Inhibits EMT and Invasion and Migration of NSCLC by Suppressing MAPK/ERK1/2 and PI3K/AKT/ mTOR Signaling Pathways7
Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug 7
The Synergistic Effect of Ruthenium Complex Δ-Ru1 and Doxorubicin in a Mouse Breast Cancer Model7
Ubiquitination-related Gene UBTD1 Mediates Poor Prognosis of Colorectal Cancer and Affects Colorectal Cancer Cell Proliferation and Ferroptosis7
Application of Nano Drug Delivery System (NDDS) in Cancer Therapy: A Perspective7
Patent Selections7
Fatty Acid Synthase (FASN): A Patent Review Since 2016-Present7
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