OOIR: Observatory of International Research

Papers

(The median citation count of Immune Network is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Regulation of Adaptive Immunity by Lipid Post-translational Modifications	101
Metabolic Signaling as a Driver of T Cell Aging	97
Exosomes in Action: Unraveling Their Role in Autoimmune Diseases and Exploring Potential Therapeutic Applications	33
Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants	26
Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management	22
Tobacco Smoking Could Accentuate Epithelial-Mesenchymal Transition and Th2-Type Response in Patients With Chronic Rhinosinusitis With Nasal Polyps	21
The Impact of Pulmonary Disorders on Neurological Health (Lung-Brain Axis)	21
Recombinant Human IL-32θ Induces Polarization Into M1-like Macrophage in Human Monocytic Cells	21
Omicron Subvariants, Including BA.4 and BA.5, Substantially Preserve T Cell Epitopes of Ancestral SARS-CoV-2	20
Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages	18
Multi-Layered Mechanisms of Immunological Tolerance at the Maternal-Fetal Interface	17
As a Modulator, Multitasking Roles of SIRT1 in Respiratory Diseases	15
The Role of Inflammasome-Associated Innate Immune Receptors in Cancer	14
Application of Antimicrobial Peptide LL-37 as an Adjuvant for Middle East Respiratory Syndrome-Coronavirus Antigen Induces an Efficient Protective Immune Response Against Viral Infection After Intrana	14
Golden Age of Immunotherapy: Challenges and Opportunities	13
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection	13
Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells	12
Comparison of Waning Immunity Between Booster Vaccination and 2-Dose Vaccination With BNT162b2	12
Immune Cells Are Differentially Affected by SARS-CoV-2 Viral Loads in K18-hACE2 Mice	12
Metabolic Challenges in Anticancer CD8 T Cell Functions	12
Sphingosylphosphorylcholine Promotes Th9 Cell Differentiation Through Regulation of Smad3, STAT5, and β-Catenin Pathways	11
Gut Microbial Metabolites on Host Immune Responses in Health and Disease	11
Neutrophil Migration Is Mediated by VLA-6 in the Inflamed Adipose Tissue	11
Immunologic Basis of Type 2 Biologics for Severe Asthma	11
Complement C5a Receptor Signaling in Macrophages Enhances Trained Immunity Through mTOR Pathway Activation	11

Mitochondrial Transplantation Ameliorates the Development and Progression of Osteoarthritis	10
Targeted Immunotherapy for Autoimmune Disease	10
Diverse Functions of Macrophages in Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease: Bridging Inflammation and Metabolism	9
SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways	9
Comprehensive Transcriptomic Analysis for Thymic Epithelial Cells of Aged Mice and Humans	9
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	9
Comprehensive Analysis of Epstein-Barr Virus LMP2A-Specific CD8⁺ and CD4⁺ T Cell Responses Restricted to Each HLA Class I and II Allotype Within an Individual	9
Promising Therapeutic Effects of Embryonic Stem Cells-Origin Mesenchymal Stem Cells in Experimental Pulmonary Fibrosis Models: Immunomodulatory and Anti-Apoptotic Mechanisms	8
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	8
Beyond Tumor Borders: Intratumoral Microbiome Effects on Tumor Behavior and Therapeutic Responses	8
Human CD8⁺ T-Cell Populations That Express Natural Killer Receptors	8
Regulatory T Cell Metabolism: A Promising Therapeutic Target for Cancer Treatment?	8
SARS-CoV-2 mRNA Vaccine Elicits Sustained T Cell Responses Against the Omicron Variant in Adolescents	8
1,3-Dibenzyl-5-Fluorouracil Prevents Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Differentiation	8
Bifidobacterium longum RAPO Attenuates Dermal and Pulmonary Fibrosis in a Mouse Model of Systemic Sclerosis through Macrophage Modulation and Growth of Short-Chain Fatty Acid Producers	7
IL-17 Imbalance Promotes the Pyroptosis in Immune-Mediated Liver Injury Through STAT3-IFI16 Axis	7
A Dynamic Interplay of Innate Immune Responses During Urinary Tract Infection	7
Modeling Incorporating the Severity-Reducing Long-term Immunity: Higher Viral Transmission Paradoxically Reduces Severe COVID-19 During Endemic Transition	7
Germinal Center Response to mRNA Vaccination and Impact of Immunological Imprinting on Subsequent Vaccination	7
T Cell Microvilli: Finger-Shaped External Structures Linked to the Fate of T Cells	7
Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22	7
Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46	7
Cytokines, Vascular Endothelial Growth Factors, and PlGF in Autoimmunity: Insights From Rheumatoid Arthritis to Multiple Sclerosis	6
Immunopathology and Immunotherapy of Inflammatory Skin Diseases	6
Impairment of Mitochondrial ATP Synthesis Induces RIPK3-dependent Necroptosis in Lung Epithelial Cells During Lung Injury by Lung Inflammation	6
IL-34 Aggravates Steroid-Induced Osteonecrosis of the Femoral Head via Promoting Osteoclast Differentiation	6
Roles of Virtual Memory T Cells in Diseases	6
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance	6
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer	5
IFN-γ: A Crucial Player in the Fight Against HBV Infection?	5
Immune Checkpoint Inhibitors in 10 Years: Contribution of Basic Research and Clinical Application in Cancer Immunotherapy	5
Cytokine Inductions and Intracellular Signal Profiles by Stimulation of dsRNA and SEB in the Macrophages and Epithelial Cells	4
Pre-existing Immunity to Endemic Human Coronaviruses Does Not Affect the Immune Response to SARS-CoV-2 Spike in a Murine Vaccination Model	4
Antibody Response Induced by Two Doses of ChAdOx1 nCoV-19, mRNA-1273, or BNT162b2 in Liver Transplant Recipients	4
Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier	4
Mesenchymal Stem Cells Attenuate Asthmatic Inflammation and Airway Remodeling by Modulating Macrophages/Monocytes in the IL-13-Overexpressing Mouse Model	4
Beyond the CAR T Cells: TIL Therapy for Solid Tumors	4
Interferon-driven Metabolic Reprogramming and Tumor Microenvironment Remodeling	3
Optimising IL-2 for Cancer Immunotherapy	3
CAR T Cell Immunotherapy Beyond Haematological Malignancy	3
Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates	3
Modulation of Immune Responses by Metabolic Reprogramming: The Key Role of Immunometabolism	3
Activation of Immune Responses Through the RIG-I Pathway Using TRITC-Dextran Encapsulated Nanoparticles	3
Interleukin-18 Binding Protein (IL-18BP): A Long Journey From Discovery to Clinical Application	3
Innate Type-2 Cytokines: From Immune Regulation to Therapeutic Targets	3
Bone Marrow Progenitors and IL-2 Signaling Contribute to the Strain Differences of Kidney Innate Lymphoid Cells	3
Molecular Mechanisms of T Helper Cell Differentiation and Functional Specialization	3
Change of Dendritic Cell Subsets Involved in Protection Against Listeria monocytogenes Infection in Short-Term-Fasted Mice	3
Cytokine Storm Related to CD4⁺ T Cells in Influenza Virus-Associated Acute Necrotizing Encephalopathy	2
Comprehensive Lipid Profiling Recapitulates Enhanced Lipolysis and Fatty Acid Metabolism in Intimal Foamy Macrophages From Murine Atherosclerotic Aorta	2

MiR-182-5p Mediated by Exosomes Derived From Bone Marrow Mesenchymal Stem Cell Attenuates Inflammatory Responses by Targeting TLR4 in a Mouse Model of Myocardial Infraction	2
Outstanding Features of COVID-19 Overlapping Primary Immunodeficiency in Children	2
Microbial Components and Effector Molecules in T Helper Cell Differentiation and Function	2
Microbial Modulation in Inflammatory Bowel Diseases	2
Increased B Cell Understanding Puts Improved Vaccine Platforms Just Over the Horizon	2
Low Neutralizing Activities to the Omicron Subvariants BN.1 and XBB.1.5 of Sera From the Individuals Vaccinated With a BA.4/5-Containing Bivalent mRNA Vaccine	2
COVID-19 Vaccination Alters NK Cell Dynamics and Transiently Reduces HBsAg Titers Among Patients With Chronic Hepatitis B	2
Integration and Reanalysis of Four RNA-Seq Datasets Including BALF, Nasopharyngeal Swabs, Lung Biopsy, and Mouse Models Reveals Common Immune Features of COVID-19	2
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain	2
Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response	2
Back to the T Cell: Basic and Clinical Application	2
RNA Metabolism in T Lymphocytes	2
Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect At-risk COVID-19 Patients	2
Why Should We Consider Potential Roles of Oral Bacteria in the Pathogenesis of Sjögren Syndrome?	2