OOIR: Observatory of International Research

Papers

(The TQCC of Immune Network is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages	131
Sphingosylphosphorylcholine Promotes Th9 Cell Differentiation Through Regulation of Smad3, STAT5, and β-Catenin Pathways	126
Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants	52
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk	35
Beyond Tumor Borders: Intratumoral Microbiome Effects on Tumor Behavior and Therapeutic Responses	35
Distinct T Cell Dysregulation Reflects Disease Severity and Progression in Infantile Epileptic Spasms Syndrome and Lennox-Gastaut Syndrome	33
Modeling Incorporating the Severity-Reducing Long-term Immunity: Higher Viral Transmission Paradoxically Reduces Severe COVID-19 During Endemic Transition	32
Impairment of Mitochondrial ATP Synthesis Induces RIPK3-dependent Necroptosis in Lung Epithelial Cells During Lung Injury by Lung Inflammation	32
IL-1 Receptor Dynamics in Immune Cells: Orchestrating Immune Precision and Balance	31
Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46	31
The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer	31
Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22	26
Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier	24
Intestinal Dysbiosis Caused by Epithelial Fabp6 Gene Disruption Exacerbates Gut Inflammatory Disease	24
Optimising IL-2 for Cancer Immunotherapy	24
CAR T Cell Immunotherapy Beyond Haematological Malignancy	23
Increased B Cell Understanding Puts Improved Vaccine Platforms Just Over the Horizon	21
Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation	21
Strong Immune Privileges of MSC and Other Nes-GFP⁺ Progenitors in Bone Marrow of Transgenic Mice	21
Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response	20
Outstanding Features of COVID-19 Overlapping Primary Immunodeficiency in Children	20
STING-STAT6 Signaling Pathway Promotes IL-4⁺ and IFN-α⁺ Fibrotic T Cell Activation and Exacerbates Scleroderma in SKG Mice	20
Altered Frequency, Activation, and Clinical Relevance of Circulating Innate and Innate-Like Lymphocytes in Patients With Alcoholic Liver Cirrhosis	19
Development of Bispecific Antibody for Cancer Immunotherapy: Focus on T Cell Engaging Antibody	19
Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages	18

Increased Inflammatory Responses in Patients With Active Disseminated Non-Tuberculous Mycobacterial Infection and High Anti-Interferon-Gamma Autoantibodies	18
Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease	18
Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection	18
COVID-19 Therapeutics: An Update on Effective Treatments Against Infection With SARS-CoV-2 Variants	17
Cigarette Smoke Extract-Treated Mouse Airway Epithelial Cells-Derived Exosomal LncRNA MEG3 Promotes M1 Macrophage Polarization and Pyroptosis in Chronic Obstructive Pulmonary Disease by Upregulating T	17
Vaccine Strategy That Enhances the Protective Efficacy of Systemic Immunization by Establishing Lung-Resident Memory CD8 T Cells Against Influenza Infection	16
Oxidized LDL Accelerates Cartilage Destruction and Inflammatory Chondrocyte Death in Osteoarthritis by Disrupting the TFEB-Regulated Autophagy-Lysosome Pathway	16
Exploring the Potential of Glycolytic Modulation in Myeloid-Derived Suppressor Cells for Immunotherapy and Disease Management	16
Neutrophil Migration Is Mediated by VLA-6 in the Inflamed Adipose Tissue	16
Regulatory T Cell Metabolism: A Promising Therapeutic Target for Cancer Treatment?	15
Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells	15
Unlocking IL-33: New Insights into Tumor Immunity	15
SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways	15
SiglecF Expressing Neutrophils Exacerbate Th17-Mediated Autoimmune Neuroinflammation	15
Enigmatic Roles of Complement Anaphylatoxin Signaling in Health and Disease	14
Immunopathology and Immunotherapy of Inflammatory Skin Diseases	14
Soluble CCR2-Expressing Mesenchymal Stem Cells Inhibit Osteoarthritis Development and Progression	14
Shaping Heterogeneity of Naive CD8⁺ T Cell Pools	14
Change of Dendritic Cell Subsets Involved in Protection Against Listeria monocytogenes Infection in Short-Term-Fasted Mice	14
Mitochondria Activity and CXCR4 Collaboratively Promote the Differentiation of CD11c⁺ B Cells Induced by TLR9 in Lupus	13
Virus-like Particle Vaccines Containing RSV Fusion Protein Cleavage Mutations Are Immunogenic and Protective in Cotton Rats With a Prime Dose	13
NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain	13