Hereditas

Article	Citations
Insulin-like growth factor binding protein 2: a core biomarker of left ventricular dysfunction in dilated cardiomyopathy	41
A novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients	29
Prognostic value of Linc00662/miR-16-5p/FASN in cervical cancer and regulation of tumor progression	28
Upregulation of CENPM is associated with poor clinical outcome and suppression of immune profile in clear cell renal cell carcinoma	22
Integrating bioinformatics analysis, machine learning, and experimental validation to identify pyroptosis-related genes in the diagnosis of sepsis combined with acute liver failure	22
Prognostic value of LncRNA PSMA3-AS1 in prostate cancer and its potential regulatory mechanism	21
Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease	19
Mediating Mendelian randomization in the proteome identified potential drug targets for obesity-related allergic asthma	18
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging	18
E2F1-driven EXOSC10 transcription promotes hepatocellular carcinoma growth and stemness: a potential therapeutic target	17
Systematic evaluations of forensic effectiveness and genetic structures of two ethnic groups in Northwest China using a self-developed Multi-InDel panel	16
An 8-gene predicting survival model of hepatocellular carcinoma (HCC) related to pyroptosis and cuproptosis	16
Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-plex DIP panel	14
A cuproptosis-related lncRNA signature for predicting prognosis and immunotherapy response of lung adenocarcinoma	13
An artificial neural network model based on autophagy-related genes in childhood systemic lupus erythematosus	11
LncRNA WAC-AS1 expression in human tumors correlates with immune infiltration and affects prognosis	11
Cell-free DNA from plasma as a promising alternative for detection of gene mutations in patients with Maffucci syndrome	11
Gene expression trend changes in breast cancer populations over two decades: insights from The Cancer Genome Atlas database	10
Comprehensive analysis to identify pseudogenes/lncRNAs-hsa-miR-200b-3p-COL5A2 network as a prognostic biomarker in gastric cancer	10
WMRCA + : a weighted majority rule-based clustering method for cancer subtype prediction using metabolic gene sets	10
In silico and in vitro assessment of TP53, ATM, RAD51, and BAX genes in gastric cancer and their contribution to radiotherapy resistance	9
Enhancer analysis of the Drosophila zinc finger transcription factor Earmuff by gene targeting	9
Stable populations and Hardy-Weinberg equilibrium	9
SREBF1, a target gene of multiple sclerosis and coronary heart disease: based on mendelian randomization study	8
Susceptibility genes of hyperuricemia and gout	8

The causal effects between low back pain and cerebrospinal fluid metabolites: a two-sample Mendelian randomization study	8
RNA-Seq based transcriptome analysis in oral lichen planus	8
Structural and functional assessment of TBX20 gene variants in pediatric ventricular septal defect	8
Exploring the anticancer potential of green synthesized Zn/Cu nanocomposites from olive leaves against lung cancer	7
A guide to barley mutants	7
Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics	7
CircCENPM serves as a CeRNA to aggravate nasopharyngeal carcinoma metastasis and stemness via enhancing BMI1	7
MiR−33 as a novel diagnostic biomarker for distinguishing cholesterol from adenomatous polyps: a case-control study	7
Predictive value of microRNA-133a-3p for early urinary incontinence after radical prostatectomy for prostate cancer and its correlation with rehabilitation effects	6
Diagnostic and prognostic value of miR-146b-5p in acute pancreatitis	6
Regulatory role of ezrin in esophageal cancer progression via the PI3K-AKT signaling pathway	6
Qingjie Fuzheng granules attenuate cancer cachexia by restoring gut microbiota homeostasis and suppressing IL-6/NF-κB signaling in colorectal adenocarcinoma	6
Mechanism of LINC00958 in ferroptosis of breast cancer through the SRSF1/GPX4 axis	6
Identification and validation of CDC20 and ITCH as ubiquitination related biomarker in idiopathic pulmonary fibrosis	6
Exploring the mechanism of dendrobine in treating metabolic associated fatty liver disease based on network pharmacology and experimental validation	5
Genetic analysis of albinism caused by compound heterozygous mutations of the OCA2 gene in a Chinese family	5
Association between chronic obstructive pulmonary disease and osteoporosis: Mendelian randomization combined with bibliometric analysis	5
Genetic overlap between sarcoidosis and lung cancer: a combined in silico and in vitro approach	5
The causal relationships between gut microbiota and venous thromboembolism: a Mendelian randomization study	5
Mechanisms of Cynarine for treatment of non-alcoholic fatty liver disease based on the integration of network pharmacology, molecular docking and cell experiment	5
β-Nicotinamide mononucleotide alleviates Alcohol-Induced liver injury in a mouse model through activation of NAD+/SIRT1 signaling pathways	5
Integrated multi-omics analysis and machine learning refine molecular subtypes and clinical outcome for hepatocellular carcinoma	5
Ulnar nerve entrapment syndrome: a special case report	5
Revisiting bicoid function: complete inactivation reveals an additional fundamental role in Drosophila egg geometry specification	5
Identification of N6-methyladenosine-associated ferroptosis biomarkers in cervical cancer	5
Epithelial zinc finger protein in lung adenocarcinoma: prognostic biomarker with molecular and clinical implications	4
Correction to: Performance comparison of four types of target enrichment baits for exome DNA sequencing	4
The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification	4
γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway	4
Screening of ulcerative colitis biomarkers and potential pathways based on weighted gene co-expression network, machine learning and ceRNA hypothesis	4
Decoding mitochondrial stress genes in DCM: towards precision diagnosis and therapy	4
Hsa_circ_0006006 is a potential biomarker for prognosis and cisplatin resistance in non-small cell lung cancer	4
Investigating the clinical significance of OAS family genes in breast cancer: an in vitro and in silico study	4
m6A transferase KIAA1429 mediates the upregulation of LncRNA LINC00968 promoting the progression of gastric cancer cells	4
A bioinformatics analysis of the target role of miRNA-431-5p on KLK6 in colorectal cancer	4
Genetic insights into therapeutic targets for gout: evidence from a multi-omics mendelian randomization study	4
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo	4
Investigation of the molecular mechanism of Xiaoluo Wan in thyroid-associated ophthalmopathy: network analysis and in vivo study	4
Fine construction of gene coexpression network analysis using GTOM and RECODE detected a critical module of neuroblastoma stages 4 and 4S	4
Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature	4
The novel circFKBP8/miR-432-5p/E2F7 cascade functions as a regulatory network in breast cancer	4
BHLHE40-mediated RGS16 upregulation: a driver propelling gastric cancer progression via ferroptosis suppression	4
A novel risk model consisting of nine platelet-related gene signatures for predicting prognosis, immune features and drug sensitivity in glioma	4
Circular RNAs: novel noncoding players in male infertility	4
EZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4	3
Why Hereditas leads hereditary cancer awareness now more than ever	3
Yi Gong San inhibits tumor immune escape by sensitizing colorectal cancer stem cells via the NF-κB pathway	3
Managing gastrointestinal involvement in cutaneomucosal venous malformation: safety and efficacy of endoscopic sclerotherapy	3
Trimeric complexes of Antp-TBP with TFIIEβ or Exd modulate transcriptional activity	3
Development and implementation of an etiology-based diagnostic framework for acute abdominal pain in emergency settings	3

Role of necroptosis and immune infiltration in essential thrombocytosis	3
Identification of biomarkers, immune infiltration landscape, and treatment targets of ischemia–reperfusion acute kidney injury at an early stage by bioinformatics methods	3
Integrated single-cell and bulk transcriptomic profiling reveals cancer-associated fibroblast heterogeneity in glioblastoma and establishes a clinically actionable prognostic model and preliminary exp	3
Serum vitamin C levels and risk of osteoporosis: results from a cross-sectional study and Mendelian randomization analysis	3
Acetylation proteomics and metabolomics analyses reveal the involvement of starch synthase undergoing acetylation modification during UV-B stress resistance in Rhododendron Chrysanthum Pall	3
Suppression of circ_0091761 ameliorates acute myocardial infarction-induced endothelial injury through regulation of miR-1278	3
Novel variants require established frameworks: emphasizing the role of ISTH diagnostic and classification guidelines in congenital fibrinogen disorders	3
Effects of fourteen essential minerals and vitamins on acute and chronic tubulointerstitial nephritis: a multivariate Mendelian randomization study	3
Disulfidptosis classification of pancreatic carcinoma reveals correlation with clinical prognosis and immune profile	3
Elevated HMGB1 promotes the malignant progression and contributes to cisplatin resistance of non-small cell lung cancer	3
Effect of Wendan decoction granules on preventing endolymphatic hydrops and protecting vestibular function in Guinea pigs	3
WDR62 affects the progression of ovarian cancer by regulating the cell cycle	3
Daidzein and puerarin synergistically suppress gastric cancer proliferation via STAT3/FAK pathway Inhibition	2
Efficacy of red ointment in wound cavity repair following non-puerperal mastitis debridement	2
Correction: Identification and functional characterization of key biomarkers in diffuse large B-cell lymphoma: emphasis on STYX as a prognostic marker and therapeutic target	2
Editorial: Celebration of DNA Day	2
Transformation and gene-disruption in the apple-pathogen, Neonectria ditissima	2
Arecoline promotes proliferation and migration of human HepG2 cells through activation of the PI3K/AKT/mTOR pathway	2
Mutation update of SERPING1 related to hereditary angioedema in the Chinese population	2
RNA binding protein ILF3 increases CEP55 mRNA stability to enhance malignant potential of breast cancer cells and suppress ferroptosis	2
The diagnostic and prognostic value of LncRNA FAM3D-AS1 expression in nasopharyngeal carcinoma and its effect on tumor progression and cisplatin resistance	2
miR-671-5p as a diagnostic biomarker and therapeutic target in periodontitis via THBS1 regulation	2
miR-31-5p from placental and peripheral blood exosomes is a potential biomarker to diagnose preeclampsia	2
Genomics in animal breeding from the perspectives of matrices and molecules	2
LncRNA LUCAT1 as a prognostic biomarker in cholangiocarcinoma through targeting miR-141-3p: clinical and functional insights	2
Carnosic acid enhances cisplatin sensitivity and suppresses gastric cancer progression via the TP53/SLC7A11/ALOX12 axis	2
Analysis of spermidine’s effect on coronary heart disease risk using bidirectional Mendelian randomization and LC-MS/MS	2
Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses	2
A novel molecular subtypes and risk model based on inflammatory response-related lncrnas for bladder cancer	2
Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking	2
Understanding the contemporary high obesity rate from an evolutionary genetic perspective	2
Knockdown of IGF2BP2 overcomes cisplatin-resistance in lung cancer through downregulating Spon2 gene	2
Correlation between gut microbiota characteristics and non-small cell lung cancer based on macrogenomics sequencing	2
Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting	2
Protein content and HvNAM alleles in Nordic barley (Hordeum vulgare) during a century of breeding	2
A novel mutation of CTC1 leads to telomere shortening in a chinese family with interstitial lung disease	2
Development and validation of an RBP gene signature for prognosis prediction in colorectal cancer based on WGCNA	2
TGF-β1/SMOC2/AKT and ERK axis regulates proliferation, migration, and fibroblast to myofibroblast transformation in lung fibroblast, contributing with the asthma progression	2
Zebrafish nampt-a mutants are viable despite perturbed primitive hematopoiesis	2
Inhibition of microRNA-660-5p decreases breast cancer progression through direct targeting of TMEM41B	2
Metabolic heterogeneity and survival outcomes in papillary renal cell carcinoma: insights from multi-datasets and machine learning analyses	2
Identification of immune-related mitochondrial metabolic disorder genes in septic shock using bioinformatics and machine learning	2
Identification and validation of autophagy-related genes in Kawasaki disease	2
Shenling Baizhu San attenuates testicular spermatogenic dysfunction in hyperuricemic mice via dual modulation of MAPK/NF-κB and NLRP3 inflammasome pathways	2
Identification of crucial genes involved in pathogenesis of regional weakening of the aortic wall	2
TFAP2A promotes NSCLC malignant progression by enhancing AOC1 transcription	2
Mutations in the acetolactate synthase (ALS) enzyme affect shattercane (Sorghum bicolor) response to ALS-inhibiting herbicides	2
Mechanistic evaluation of a traditional herbal decoction in attenuating hepatic fibrosis via Nrf2/GPX4 pathway activation and ferroptosis inhibition	2
Screening and analysis of programmed cell death related genes and targeted drugs in sepsis	2
Multi-Omics analysis and in vitro validation reveal diagnostic and therapeutic roles of novel hub genes in ovarian cancer	2
The potential role of biomarkers CD28 and PF4 in the pathogenesis of idiopathic pulmonary fibrosis and their impact on the prognosis: an immune microenvironment analysis	2
Programmed death 1 inhibitor combined with radiotherapy decreases epidermal growth factor receptor expression in breast cancer	2
METTL3 mediates m6A methylation modification of ULBP2 and affects the progression of cervical cancer	1
Identification of components in scorpion and centipede traditional Chinese medicine formulations with potentially beneficial actions in asthma: network pharmacology and molecular docking	1
Corynoxine suppresses lung adenocarcinoma proliferation and metastasis via inhibiting PI3K/AKT pathway and suppressing Cyclooxygenase-2 expression	1
Discovering the key genes and important DNA methylation regions in breast cancer	1
Clinical significance of LINC01158 in breast cancer and inhibition of proliferation and metastasis of breast cancer cells by regulating miR-711	1
Identification of four novel hub genes as monitoring biomarkers for colorectal cancer	1
IFNAR1 gene mutation may contribute to developmental stuttering in the Chinese population	1
DNA hypomethylation of INHBA promotes tumor progression and predicts prognosis and immune status of gastric cancer	1
Novel Antennapedia and Ultrabithorax trimeric complexes with TBP and Exd regulate transcription	1
Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor effect of ARL14	1
Single-cell multi-omics as a window into the non-coding transcriptome	1
Global trends in machine learning applications for single-cell transcriptomics research	1
Integrative bioinformatics analysis of high-throughput sequencing and in vitro functional analysis leads to uncovering key hub genes in esophageal squamous cell carcinoma	1
Early arteriovenous malformation mimicking pediatric capillary malformation: diagnostic value of infrared thermography	1
Investigating the shared genetic structure between rheumatoid arthritis and stroke	1
Astragaloside IV regulates FOXM1 deubiquitination to ameliorate trophoblast damage caused by high glucose	1
Decoding the PTTG family’s contribution to LUAD pathogenesis: a comprehensive study on expression, epigenetics, and therapeutic interventions	1
Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approach	1
Screening, identification, and experimental validation of SUMOylation biomarkers in Parkinson’s disease	1
RBM15 enhances paclitaxel resistance in triple-negative breast cancer by targeting m6A methylation of TNFSF9 and inducing polarization of tumor-associated macrophages to M2 phenotype	1
Variations in the TAS2R38 gene among college students in Hubei	1
Deciphering the potential ability of RG108 in cisplatin-induced HEI-OC1 ototoxicity: a research based on RNA-seq and molecular biology experiment	1
The bibliometric analysis of research on traditional Chinese medicine regulating gut microbiota for cancer treatment from 2014 to 2024	1
Knockdown of AMIGO2 suppresses proliferation and migration through regulating PPAR-γ in bladder cancer	1
Clinical significance and biological function of PRKCQ-AS1/miR-582-3p expression in LUAD	1
Mechanism of miR-107/HMOX1 axis in hepatic sinusoidal endothelial cells stimulated by ischemia-reperfusion injury	1
Complex vascular anomalies and tissue overgrowth of limbs associated with increased skin temperature and peripheral venous dilatation: parks weber syndrome or PROS?	1
The Jan Sjödin faba bean mutant collection: morphological and molecular characterization	1

Trends in enhanced recovery after surgery (ERAS) in thoracic surgery from a bibliometric insight	1
Exploring MAP3K genes in gastric cancer: biomarkers, tumor microenvironment dynamics, and chemotherapy resistance	1
Identification of subtypes and biomarkers associated with disulfidptosis-related ferroptosis in ulcerative colitis	1
Application of bioinformatics analysis and molecular docking to study the mechanism of Qingying decoction in treating psoriasis	1
Identification of anoikis-related genes in heart failure: bioinformatics and experimental validation	1
Impact of early blood purification on serum inflammatory mediators and hemorheology in severe acute pancreatitis	1
Can Omega-3 prevent the accidence of stroke: a mendelian randomization study	1
Multi-omics Mendelian randomization integrating RNA-seq, eQTL and pQTL data revealed CPXM1 as a potential drug target for osteoporosis	1
Comparative pharmacognosy and secondary metabolite analysis of Balanophorae herbs from different sources	1
Mir-615-5p inhibits cervical cancer progression by targeting TMIGD2	1
A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2	1
Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells	1
Identification and development of the novel 7-genes diagnostic signature by integrating multi cohorts based on osteoarthritis	1
Exploring the potential mechanisms of m6A modification in septic acute respiratory distress syndrome: a bioinformatics analysis	1
Syndromic capillary malformation with leg length discrepancy: Parkes-Weber syndrome treated by embolization, chemotherapy and Ilizarov technique	1
m6A-related lncRNA-based immune infiltration characteristic analysis and prognostic model for colonic adenocarcinoma	1
A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family	1
RNA-binding protein gene NOP58 exhibits crucial prognostic and therapeutic value in Ewing sarcoma	1
Identification of mitophagy-related genes in patients with acute myocardial infarction	1
A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype	1
Mir-150-5p distinguishes acute pulmonary embolism, predicts the occurrence of pulmonary arterial hypertension, and regulates ox-LDL-induced endothelial cell injury	1
Modifiable risk factors that mediate the effect of insomnia on the risk of low back pain: a network mendelian randomization study	1
Reduced miR-338-3p contributes to polycystic ovarian syndrome by inhibiting proliferation and enhancing apoptosis	1
Key wound healing genes as diagnostic biomarkers and therapeutic targets in uterine corpus endometrial carcinoma: an integrated in silico and in vitro study	1
Immunomodulatory insights of monoterpene glycosides in endometriosis: immune infiltration and target pathways analysis	1
Whole-exome sequencing detected a novel AIFM1 variant in a Han-Chinese family with Cowchock syndrome	1
Integrated analysis of N6-methyladenosine- and 5-methylcytosine-related long non-coding RNAs for predicting prognosis in cervical cancer	1
miR-370-3p affects the progression of postmenopausal osteoporosis through targeting INO80	1
Identification of regulator gene and pathway in myocardial ischemia-reperfusion injury: a bioinformatics and biological validation study	1
Identification and experimental validation of biomarkers associated with the endocannabinoid system in major depressive disorder	1
LncRNA FLG-AS1 inhibits esophageal squamous cell carcinoma by regulating the miR-23a-3p/HOXD10 axis	1
SOLAMEN syndrome with cardiovascular damage	1
Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning	1
Exploration of the molecular mechanism of modified Danggui Liuhuang Decoction in treating central precocious puberty and its effects on hypothalamic-pituitary-gonadal axis hormones	1
Circ_RPPH1 promotes bladder urothelium carcinoma proliferation and EMT by recruiting and binding to EIF4 A3	1
Integrated bioinformatic analysis identifies GADD45B as an immune-related prognostic biomarker in skin cutaneous melanoma	1
EPHX1 enhances drug resistance to regorafenib by activating the JAK/STAT signaling pathway in hepatocellular carcinoma cell lines	1
Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis	1
Comprehensive analysis revealed the immunoinflammatory targets of rheumatoid arthritis based on intestinal flora, miRNA, transcription factors, and RNA-binding proteins databases, GSEA and GSVA pathwa	1
USP8 protects rat-derived H9C2 cardiomyocytes from doxorubicin-triggered ferroptosis and cell death through deubiquitination-mediated stabilization of MDM4	1
ADME gene-driven prognostic model for bladder cancer: a breakthrough in predicting survival and personalized treatment	1