OOIR: Observatory of International Research

Papers

(The median citation count of Hereditas is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Insulin-like growth factor binding protein 2: a core biomarker of left ventricular dysfunction in dilated cardiomyopathy	39
A novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients	26
Upregulation of CENPM is associated with poor clinical outcome and suppression of immune profile in clear cell renal cell carcinoma	23
Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease	20
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging	20
LncRNA WAC-AS1 expression in human tumors correlates with immune infiltration and affects prognosis	19
E2F1-driven EXOSC10 transcription promotes hepatocellular carcinoma growth and stemness: a potential therapeutic target	19
Mediating Mendelian randomization in the proteome identified potential drug targets for obesity-related allergic asthma	17
An artificial neural network model based on autophagy-related genes in childhood systemic lupus erythematosus	16
Enhancer analysis of the Drosophila zinc finger transcription factor Earmuff by gene targeting	16
Regulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses	15
Cell-free DNA from plasma as a promising alternative for detection of gene mutations in patients with Maffucci syndrome	15
Gene expression trend changes in breast cancer populations over two decades: insights from The Cancer Genome Atlas database	14
Stable populations and Hardy-Weinberg equilibrium	13
A cuproptosis-related lncRNA signature for predicting prognosis and immunotherapy response of lung adenocarcinoma	13
An 8-gene predicting survival model of hepatocellular carcinoma (HCC) related to pyroptosis and cuproptosis	11
Systematic evaluations of forensic effectiveness and genetic structures of two ethnic groups in Northwest China using a self-developed Multi-InDel panel	11
Network analysis of potential risk genes for psoriasis	10
Comprehensive analysis to identify pseudogenes/lncRNAs-hsa-miR-200b-3p-COL5A2 network as a prognostic biomarker in gastric cancer	10
RNA-Seq based transcriptome analysis in oral lichen planus	10
A guide to barley mutants	10
Exploring the anticancer potential of green synthesized Zn/Cu nanocomposites from olive leaves against lung cancer	10
Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-plex DIP panel	10
CircCENPM serves as a CeRNA to aggravate nasopharyngeal carcinoma metastasis and stemness via enhancing BMI1	9
The causal effects between low back pain and cerebrospinal fluid metabolites: a two-sample Mendelian randomization study	9

MiR−33 as a novel diagnostic biomarker for distinguishing cholesterol from adenomatous polyps: a case-control study	9
Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma	9
SREBF1, a target gene of multiple sclerosis and coronary heart disease: based on mendelian randomization study	8
Susceptibility genes of hyperuricemia and gout	8
Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics	8
Identification and validation of CDC20 and ITCH as ubiquitination related biomarker in idiopathic pulmonary fibrosis	7
Predictive value of microRNA-133a-3p for early urinary incontinence after radical prostatectomy for prostate cancer and its correlation with rehabilitation effects	7
Modulating the bicoid gradient in space and time	7
Dynamic co-expression modular network analysis in nonalcoholic fatty liver disease	7
Mechanisms of Cynarine for treatment of non-alcoholic fatty liver disease based on the integration of network pharmacology, molecular docking and cell experiment	6
Diagnostic and prognostic value of miR-146b-5p in acute pancreatitis	6
Exploring the mechanism of dendrobine in treating metabolic associated fatty liver disease based on network pharmacology and experimental validation	6
Genetic analysis of albinism caused by compound heterozygous mutations of the OCA2 gene in a Chinese family	6
The causal relationships between gut microbiota and venous thromboembolism: a Mendelian randomization study	6
Revisiting bicoid function: complete inactivation reveals an additional fundamental role in Drosophila egg geometry specification	5
Investigating the clinical significance of OAS family genes in breast cancer: an in vitro and in silico study	5
Identification of N6-methyladenosine-associated ferroptosis biomarkers in cervical cancer	5
m6A transferase KIAA1429 mediates the upregulation of LncRNA LINC00968 promoting the progression of gastric cancer cells	5
Fine construction of gene coexpression network analysis using GTOM and RECODE detected a critical module of neuroblastoma stages 4 and 4S	5
Integrated multi-omics analysis and machine learning refine molecular subtypes and clinical outcome for hepatocellular carcinoma	5
Hsa_circ_0006006 is a potential biomarker for prognosis and cisplatin resistance in non-small cell lung cancer	5
The unidirectional phylogeny of Homo sapiens anchors the origin of modern humans in Eurasia	4
Effects of fourteen essential minerals and vitamins on acute and chronic tubulointerstitial nephritis: a multivariate Mendelian randomization study	4
Screening of ulcerative colitis biomarkers and potential pathways based on weighted gene co-expression network, machine learning and ceRNA hypothesis	4
A novel risk model consisting of nine platelet-related gene signatures for predicting prognosis, immune features and drug sensitivity in glioma	4
Correction to: Performance comparison of four types of target enrichment baits for exome DNA sequencing	4
The novel circFKBP8/miR-432-5p/E2F7 cascade functions as a regulatory network in breast cancer	4
The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification	4
BHLHE40-mediated RGS16 upregulation: a driver propelling gastric cancer progression via ferroptosis suppression	4
Disulfidptosis classification of pancreatic carcinoma reveals correlation with clinical prognosis and immune profile	4
Identification of biomarkers, immune infiltration landscape, and treatment targets of ischemia–reperfusion acute kidney injury at an early stage by bioinformatics methods	4
Genetic insights into therapeutic targets for gout: evidence from a multi-omics mendelian randomization study	4
γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway	4
A bioinformatics analysis of the target role of miRNA-431-5p on KLK6 in colorectal cancer	4
Decoding mitochondrial stress genes in DCM: towards precision diagnosis and therapy	4
EZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4	4
Yi Gong San inhibits tumor immune escape by sensitizing colorectal cancer stem cells via the NF-κB pathway	4
Serum vitamin C levels and risk of osteoporosis: results from a cross-sectional study and Mendelian randomization analysis	4
Association between chronic obstructive pulmonary disease and osteoporosis: Mendelian randomization combined with bibliometric analysis	4
Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature	4
Circular RNAs: novel noncoding players in male infertility	4
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo	4
Role of necroptosis and immune infiltration in essential thrombocytosis	3
Elevated HMGB1 promotes the malignant progression and contributes to cisplatin resistance of non-small cell lung cancer	3
Screening and analysis of programmed cell death related genes and targeted drugs in sepsis	3
WDR62 affects the progression of ovarian cancer by regulating the cell cycle	3
Identification of crucial genes involved in pathogenesis of regional weakening of the aortic wall	3
An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family	3
Knockdown of IGF2BP2 overcomes cisplatin-resistance in lung cancer through downregulating Spon2 gene	3
Trimeric complexes of Antp-TBP with TFIIEβ or Exd modulate transcriptional activity	3

Acetylation proteomics and metabolomics analyses reveal the involvement of starch synthase undergoing acetylation modification during UV-B stress resistance in Rhododendron Chrysanthum Pall	3
Mutations in the acetolactate synthase (ALS) enzyme affect shattercane (Sorghum bicolor) response to ALS-inhibiting herbicides	3
Novel variants require established frameworks: emphasizing the role of ISTH diagnostic and classification guidelines in congenital fibrinogen disorders	3
Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting	3
Mutation update of SERPING1 related to hereditary angioedema in the Chinese population	3
Understanding the contemporary high obesity rate from an evolutionary genetic perspective	3
RNA binding protein ILF3 increases CEP55 mRNA stability to enhance malignant potential of breast cancer cells and suppress ferroptosis	3
Zebrafish nampt-a mutants are viable despite perturbed primitive hematopoiesis	2
Protein content and HvNAM alleles in Nordic barley (Hordeum vulgare) during a century of breeding	2
miR-31-5p from placental and peripheral blood exosomes is a potential biomarker to diagnose preeclampsia	2
A novel molecular subtypes and risk model based on inflammatory response-related lncrnas for bladder cancer	2
Correction: Identification and functional characterization of key biomarkers in diffuse large B-cell lymphoma: emphasis on STYX as a prognostic marker and therapeutic target	2
Identification and validation of autophagy-related genes in Kawasaki disease	2
Genomics in animal breeding from the perspectives of matrices and molecules	2
Arecoline promotes proliferation and migration of human HepG2 cells through activation of the PI3K/AKT/mTOR pathway	2
A novel mutation of CTC1 leads to telomere shortening in a chinese family with interstitial lung disease	2
Efficacy of red ointment in wound cavity repair following non-puerperal mastitis debridement	2
TGF-β1/SMOC2/AKT and ERK axis regulates proliferation, migration, and fibroblast to myofibroblast transformation in lung fibroblast, contributing with the asthma progression	2
Editorial: Celebration of DNA Day	2
Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses	2
Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking	2
Identification of regulator gene and pathway in myocardial ischemia-reperfusion injury: a bioinformatics and biological validation study	2
Inhibition of microRNA-660-5p decreases breast cancer progression through direct targeting of TMEM41B	2
Daidzein and puerarin synergistically suppress gastric cancer proliferation via STAT3/FAK pathway Inhibition	2
m6A-related lncRNA-based immune infiltration characteristic analysis and prognostic model for colonic adenocarcinoma	2
Correlation between gut microbiota characteristics and non-small cell lung cancer based on macrogenomics sequencing	2
Transformation and gene-disruption in the apple-pathogen, Neonectria ditissima	2
Development and validation of an RBP gene signature for prognosis prediction in colorectal cancer based on WGCNA	2
Identification of immune-related mitochondrial metabolic disorder genes in septic shock using bioinformatics and machine learning	2
A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2	1
Identification and development of the novel 7-genes diagnostic signature by integrating multi cohorts based on osteoarthritis	1
Clinical significance of LINC01158 in breast cancer and inhibition of proliferation and metastasis of breast cancer cells by regulating miR-711	1
Deciphering the potential ability of RG108 in cisplatin-induced HEI-OC1 ototoxicity: a research based on RNA-seq and molecular biology experiment	1
Leopard syndrome: the potential cardiac defect underlying skin phenotypes	1
Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells	1
Comparative pharmacognosy and secondary metabolite analysis of Balanophorae herbs from different sources	1
Mir-615-5p inhibits cervical cancer progression by targeting TMIGD2	1
Novel Antennapedia and Ultrabithorax trimeric complexes with TBP and Exd regulate transcription	1
SOLAMEN syndrome with cardiovascular damage	1
Variations in the TAS2R38 gene among college students in Hubei	1
Identification of mitophagy-related genes in patients with acute myocardial infarction	1
Integrated analysis of N6-methyladenosine- and 5-methylcytosine-related long non-coding RNAs for predicting prognosis in cervical cancer	1
Modifiable risk factors that mediate the effect of insomnia on the risk of low back pain: a network mendelian randomization study	1
Complex vascular anomalies and tissue overgrowth of limbs associated with increased skin temperature and peripheral venous dilatation: parks weber syndrome or PROS?	1
The Jan Sjödin faba bean mutant collection: morphological and molecular characterization	1
Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning	1
Somatic frameshift mutation in PIK3CA causes CLOVES syndrome by provoking PI3K/AKT/mTOR pathway	1
Exploration of the molecular mechanism of modified Danggui Liuhuang Decoction in treating central precocious puberty and its effects on hypothalamic-pituitary-gonadal axis hormones	1
Mir-150-5p distinguishes acute pulmonary embolism, predicts the occurrence of pulmonary arterial hypertension, and regulates ox-LDL-induced endothelial cell injury	1
RNA-binding protein gene NOP58 exhibits crucial prognostic and therapeutic value in Ewing sarcoma	1
ADME gene-driven prognostic model for bladder cancer: a breakthrough in predicting survival and personalized treatment	1
Investigating the shared genetic structure between rheumatoid arthritis and stroke	1
Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approach	1
Comprehensive analysis revealed the immunoinflammatory targets of rheumatoid arthritis based on intestinal flora, miRNA, transcription factors, and RNA-binding proteins databases, GSEA and GSVA pathwa	1
Corynoxine suppresses lung adenocarcinoma proliferation and metastasis via inhibiting PI3K/AKT pathway and suppressing Cyclooxygenase-2 expression	1
A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype	1
Integrated bioinformatic analysis identifies GADD45B as an immune-related prognostic biomarker in skin cutaneous melanoma	1
Integrative bioinformatics analysis of high-throughput sequencing and in vitro functional analysis leads to uncovering key hub genes in esophageal squamous cell carcinoma	1
Knockdown of AMIGO2 suppresses proliferation and migration through regulating PPAR-γ in bladder cancer	1
Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis	1
Can Omega-3 prevent the accidence of stroke: a mendelian randomization study	1
Circ_RPPH1 promotes bladder urothelium carcinoma proliferation and EMT by recruiting and binding to EIF4 A3	1
A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family	1