OOIR: Observatory of International Research

Papers

(The TQCC of Hereditas is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
A pathogenic NR2F1 gene variant disrupts transcriptional activity and causes severe neurodevelopmental delay in Bosch-Boonstra-Schaaf syndrome	37
Identification of four novel hub genes as monitoring biomarkers for colorectal cancer	34
METTL3-dependent DLG2 inhibits the malignant progression of cervical cancer by inactivating the Hippo/YAP signaling	24
Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor effect of ARL14	20
Exploring the bidirectional causality between neuroticism and frailty: a Mendelian randomization analysis	20
Establishment and validation of a logistic regression model for prediction of septic shock severity in children	19
Exploring MAP3K genes in gastric cancer: biomarkers, tumor microenvironment dynamics, and chemotherapy resistance	19
m6A-related lncRNA-based immune infiltration characteristic analysis and prognostic model for colonic adenocarcinoma	18
HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity	18
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging	16
Bioinformatic analysis identifies potential biomarkers and therapeutic targets of septic-shock-associated acute kidney injury	15
Variations in the TAS2R38 gene among college students in Hubei	13
Investigating the shared genetic structure between rheumatoid arthritis and stroke	13
Screening of ulcerative colitis biomarkers and potential pathways based on weighted gene co-expression network, machine learning and ceRNA hypothesis	12
A novel risk model consisting of nine platelet-related gene signatures for predicting prognosis, immune features and drug sensitivity in glioma	12
Glutamine metabolism-related genes predict the prognostic risk of acute myeloid leukemia and stratify patients by subtype analysis	11
Circular RNAs: novel noncoding players in male infertility	11
ADME gene-driven prognostic model for bladder cancer: a breakthrough in predicting survival and personalized treatment	11
IFNAR1 gene mutation may contribute to developmental stuttering in the Chinese population	10
A novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients	9
Forkhead box P3 gene polymorphisms predispose to type 2 diabetes and diabetic nephropathy in the Han Chinese populations: a genetic-association and gender-based evaluation study	9
Mendel’s controlled pollination experiments in Mirabilis jalapa confirmed his discovery of the gamete theory of inheritance in Pisum	9
SOLAMEN syndrome with cardiovascular damage	9
Association of novel MUC16, MAP3K15 and ABCA1 mutation with giant congenital melanocytic nevus	9
Mendel’s terminology and notation reveal his understanding of genetics	9

A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2	9
A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family	8
Insulin-like growth factor binding protein 2: a core biomarker of left ventricular dysfunction in dilated cardiomyopathy	8
Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approach	8
Genetic insights into therapeutic targets for gout: evidence from a multi-omics mendelian randomization study	8
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo	8
LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma	7
Immunomodulatory insights of monoterpene glycosides in endometriosis: immune infiltration and target pathways analysis	7
A novel approach for breast cancer treatment: the multifaceted antitumor effects of rMeV-Hu191	7
EZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4	6
Identification of potential biomarkers for pathogenesis of Alzheimer’s disease	6
Upregulation of CENPM is associated with poor clinical outcome and suppression of immune profile in clear cell renal cell carcinoma	6
Correction to: Genetic polymorphism of IDOL gene was associated with the susceptibility of coronary artery disease in Han population in Xinjiang, China	6
Serum vitamin C levels and risk of osteoporosis: results from a cross-sectional study and Mendelian randomization analysis	5
Novel Antennapedia and Ultrabithorax trimeric complexes with TBP and Exd regulate transcription	5
The unidirectional phylogeny of Homo sapiens anchors the origin of modern humans in Eurasia	5
HOXD9/APOC1 axis promotes macrophage M1 polarization to exacerbate diabetic kidney disease progression through activating NF-κB signaling pathway	5
Comprehensive analysis of a necroptosis-associated diagnostic signature for myelodysplastic syndromes based on single-cell RNA-seq and bulk RNA-seq	5
Investigating the effects of global gene knockout of MrgF on motor performance and pain sensitivity in mice	5
Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-plex DIP panel	5
N6-methyladenosine-related lncRNAs is a potential marker for predicting prognosis and immunotherapy in ovarian cancer	4
Lipidomics-based investigation of its impact on the pathogenesis of coronary atherosclerosis: a Mendelian randomization study	4
Identification of biomarkers and mechanism exploration of ferroptosis related genes regulated by m6A in type 2 diabetes mellitus	4
Identification and validation of hub genes of synovial tissue for patients with osteoarthritis and rheumatoid arthritis	4
Cell-free DNA from plasma as a promising alternative for detection of gene mutations in patients with Maffucci syndrome	4
Identification of subtypes and biomarkers associated with disulfidptosis-related ferroptosis in ulcerative colitis	4
NPM3 as a novel oncogenic factor and poor prognostic marker contributes to cell proliferation and migration in lung adenocarcinoma	4
Mediating Mendelian randomization in the proteome identified potential drug targets for obesity-related allergic asthma	4
Disulfidptosis classification of pancreatic carcinoma reveals correlation with clinical prognosis and immune profile	4
An 8-gene predicting survival model of hepatocellular carcinoma (HCC) related to pyroptosis and cuproptosis	4
SNP-based breeding for broiler resistance to ascites and evaluation of correlated production traits	4
Identification of endoplasmic reticulum stress and mitochondrial dysfunction related biomarkers in osteoporosis	4
A novel compound heterozygous mutation in the DYNC2H1 gene in a Chinese family with Jeune syndrome	4
Functional analysis of enhancer elements regulating the expression of the Drosophila homeodomain transcription factor DRx by gene targeting	4
Whole-exome sequencing detected a novel AIFM1 variant in a Han-Chinese family with Cowchock syndrome	4
Identification of key apoptosis-related genes and immune infiltration in the pathogenesis of psoriasis	4