OOIR: Observatory of International Research

Papers

(The TQCC of Hereditas is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Insulin-like growth factor binding protein 2: a core biomarker of left ventricular dysfunction in dilated cardiomyopathy	39
A novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients	26
Upregulation of CENPM is associated with poor clinical outcome and suppression of immune profile in clear cell renal cell carcinoma	23
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging	20
Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease	20
E2F1-driven EXOSC10 transcription promotes hepatocellular carcinoma growth and stemness: a potential therapeutic target	19
LncRNA WAC-AS1 expression in human tumors correlates with immune infiltration and affects prognosis	19
Mediating Mendelian randomization in the proteome identified potential drug targets for obesity-related allergic asthma	17
An artificial neural network model based on autophagy-related genes in childhood systemic lupus erythematosus	16
Enhancer analysis of the Drosophila zinc finger transcription factor Earmuff by gene targeting	16
Regulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses	15
Cell-free DNA from plasma as a promising alternative for detection of gene mutations in patients with Maffucci syndrome	15
Gene expression trend changes in breast cancer populations over two decades: insights from The Cancer Genome Atlas database	14
Stable populations and Hardy-Weinberg equilibrium	13
A cuproptosis-related lncRNA signature for predicting prognosis and immunotherapy response of lung adenocarcinoma	13
An 8-gene predicting survival model of hepatocellular carcinoma (HCC) related to pyroptosis and cuproptosis	11
Systematic evaluations of forensic effectiveness and genetic structures of two ethnic groups in Northwest China using a self-developed Multi-InDel panel	11
Network analysis of potential risk genes for psoriasis	10
Comprehensive analysis to identify pseudogenes/lncRNAs-hsa-miR-200b-3p-COL5A2 network as a prognostic biomarker in gastric cancer	10
RNA-Seq based transcriptome analysis in oral lichen planus	10
A guide to barley mutants	10
Exploring the anticancer potential of green synthesized Zn/Cu nanocomposites from olive leaves against lung cancer	10
Comprehensive evaluations of individual discrimination, kinship analysis, genetic relationship exploration and biogeographic origin prediction in Chinese Dongxiang group by a 60-plex DIP panel	10
MiR−33 as a novel diagnostic biomarker for distinguishing cholesterol from adenomatous polyps: a case-control study	9
Favorable function of Ectonucleoside triphosphate diphosphohydrolase 1 high expression in thyroid carcinoma	9

CircCENPM serves as a CeRNA to aggravate nasopharyngeal carcinoma metastasis and stemness via enhancing BMI1	9
The causal effects between low back pain and cerebrospinal fluid metabolites: a two-sample Mendelian randomization study	9
Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics	8
SREBF1, a target gene of multiple sclerosis and coronary heart disease: based on mendelian randomization study	8
Susceptibility genes of hyperuricemia and gout	8
Dynamic co-expression modular network analysis in nonalcoholic fatty liver disease	7
Identification and validation of CDC20 and ITCH as ubiquitination related biomarker in idiopathic pulmonary fibrosis	7
Predictive value of microRNA-133a-3p for early urinary incontinence after radical prostatectomy for prostate cancer and its correlation with rehabilitation effects	7
Modulating the bicoid gradient in space and time	7
Genetic analysis of albinism caused by compound heterozygous mutations of the OCA2 gene in a Chinese family	6
The causal relationships between gut microbiota and venous thromboembolism: a Mendelian randomization study	6
Mechanisms of Cynarine for treatment of non-alcoholic fatty liver disease based on the integration of network pharmacology, molecular docking and cell experiment	6
Diagnostic and prognostic value of miR-146b-5p in acute pancreatitis	6
Exploring the mechanism of dendrobine in treating metabolic associated fatty liver disease based on network pharmacology and experimental validation	6
Revisiting bicoid function: complete inactivation reveals an additional fundamental role in Drosophila egg geometry specification	5
Investigating the clinical significance of OAS family genes in breast cancer: an in vitro and in silico study	5
Identification of N6-methyladenosine-associated ferroptosis biomarkers in cervical cancer	5
m6A transferase KIAA1429 mediates the upregulation of LncRNA LINC00968 promoting the progression of gastric cancer cells	5
Fine construction of gene coexpression network analysis using GTOM and RECODE detected a critical module of neuroblastoma stages 4 and 4S	5
Integrated multi-omics analysis and machine learning refine molecular subtypes and clinical outcome for hepatocellular carcinoma	5
Hsa_circ_0006006 is a potential biomarker for prognosis and cisplatin resistance in non-small cell lung cancer	5
Association between chronic obstructive pulmonary disease and osteoporosis: Mendelian randomization combined with bibliometric analysis	4
Identification of fatty acid metabolism-related genes in the tumor microenvironment of breast cancer by a development and validation of prognostic index signature	4
Circular RNAs: novel noncoding players in male infertility	4
Erianin inhibits the progression of DDP-resistant lung adenocarcinoma by regulating the Wnt/β-catenin pathway and activating the caspase-3 for apoptosis in vitro and in vivo	4
The unidirectional phylogeny of Homo sapiens anchors the origin of modern humans in Eurasia	4
Effects of fourteen essential minerals and vitamins on acute and chronic tubulointerstitial nephritis: a multivariate Mendelian randomization study	4
Screening of ulcerative colitis biomarkers and potential pathways based on weighted gene co-expression network, machine learning and ceRNA hypothesis	4
A novel risk model consisting of nine platelet-related gene signatures for predicting prognosis, immune features and drug sensitivity in glioma	4
Correction to: Performance comparison of four types of target enrichment baits for exome DNA sequencing	4
The novel circFKBP8/miR-432-5p/E2F7 cascade functions as a regulatory network in breast cancer	4
The mechanism of Weiqi decoction treating gastric cancer: a work based on network pharmacology and experimental verification	4
BHLHE40-mediated RGS16 upregulation: a driver propelling gastric cancer progression via ferroptosis suppression	4
Disulfidptosis classification of pancreatic carcinoma reveals correlation with clinical prognosis and immune profile	4
Identification of biomarkers, immune infiltration landscape, and treatment targets of ischemia–reperfusion acute kidney injury at an early stage by bioinformatics methods	4
Genetic insights into therapeutic targets for gout: evidence from a multi-omics mendelian randomization study	4
γ-tocotrienol regulates gastric cancer by targeting notch signaling pathway	4
A bioinformatics analysis of the target role of miRNA-431-5p on KLK6 in colorectal cancer	4
Decoding mitochondrial stress genes in DCM: towards precision diagnosis and therapy	4
EZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4	4
Yi Gong San inhibits tumor immune escape by sensitizing colorectal cancer stem cells via the NF-κB pathway	4
Serum vitamin C levels and risk of osteoporosis: results from a cross-sectional study and Mendelian randomization analysis	4
Understanding the contemporary high obesity rate from an evolutionary genetic perspective	3
RNA binding protein ILF3 increases CEP55 mRNA stability to enhance malignant potential of breast cancer cells and suppress ferroptosis	3
Role of necroptosis and immune infiltration in essential thrombocytosis	3
Elevated HMGB1 promotes the malignant progression and contributes to cisplatin resistance of non-small cell lung cancer	3
Screening and analysis of programmed cell death related genes and targeted drugs in sepsis	3
WDR62 affects the progression of ovarian cancer by regulating the cell cycle	3
Identification of crucial genes involved in pathogenesis of regional weakening of the aortic wall	3
An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family	3

Knockdown of IGF2BP2 overcomes cisplatin-resistance in lung cancer through downregulating Spon2 gene	3
Trimeric complexes of Antp-TBP with TFIIEβ or Exd modulate transcriptional activity	3
Acetylation proteomics and metabolomics analyses reveal the involvement of starch synthase undergoing acetylation modification during UV-B stress resistance in Rhododendron Chrysanthum Pall	3
Mutations in the acetolactate synthase (ALS) enzyme affect shattercane (Sorghum bicolor) response to ALS-inhibiting herbicides	3
Novel variants require established frameworks: emphasizing the role of ISTH diagnostic and classification guidelines in congenital fibrinogen disorders	3
Mechanistic insights into CDCA gene family-mediated glioblastoma progression: implications for diagnosis, prognosis, and therapeutic targeting	3
Mutation update of SERPING1 related to hereditary angioedema in the Chinese population	3