OOIR: Observatory of International Research

Papers

(The TQCC of Kaohsiung Journal of Medical Sciences is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Issue Information	107
Nuciferine inhibits osteoclast formation through suppressing glycolysis metabolic programming and ROS production	30
Mitochondrial DNA copy number as a mediator of the relationship between insulin resistance and cognitive function in patients with euthymic bipolar disorder	29
Rosuvastatin Upregulates RCOR1 to Repress C10ORF10 Transcription and Alleviate Oxidative Stress and Plaque Formation in Atherosclerosis	27
Suppression of cAMP/PKA/CREB signaling ameliorates retinal injury in diabetic retinopathy	23
Involvement of the miR‐128‐3p/KDM3A/NLRP3 Axis in High Glucose‐Induced Inflammatory Injury in Retinal Endothelial Cells	22
Impact of Environmental and Seasonal Factors on Spontaneous Pneumomediastinum With and Without Pneumorrhachis	21
Role of reimbursement and Physicians' awareness in the survival of sorafenib‐eligible advanced hepatocellular carcinoma patients	20
	19
Issue Information	19
Decision‐making processes in artificial intelligence applications in dentomaxillofacial radiology from the perspective of Wittgenstein	19
Expression of serum miR‐135a in patients with allergic rhinitis and its relationship with Treg/Th17 balance	18
Circular RNA circCD44 targets methyltransferase‐like 3/homeobox containing 1 to facilitate esophageal squamous cell carcinoma progression	17
Antithrombotic use in retinal artery occlusion: A narrative review	17
Limited sorafenib anticancer effects on primary cultured hepatocellular carcinoma cells with high NANOG expression	16
Cough syncope: A familiar stranger	16
A novel use of neostigmine reversal for intraoperative neural monitoring during thyroid surgery	16
Enhancing therapeutic potential: Human adipose‐derived mesenchymal stem cells modified with recombinant adeno‐associated virus expressing VEGF165 gene for peripheral nerve injury	15
Different doses of vitamin D supplementation to nonsurgical treatment for vitamin‐D‐insufficient patients with diabetic periodontitis and the effect on gingival BMP‐2 levels	15
LINC01871 facilitates cervical cancer cell migration and immune escape by targeting miR‐873‐3p/MAP3K2 axis	15
Exploration of anti‐leukemic effect of soft coral‐derived 13‐acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock protein 90 and topoisomerase I	15
Sublingual clear cell carcinoma with liver metastasis: A case report and literature review	15
A 4‐month‐old female infant with complete colonic duplication presenting with stool leaking out of the vestibule	15
MiR‐32‐5p promoted epithelial‐to‐mesenchymal transition of oral squamous cell carcinoma cells via regulating the KLF2/CXCR4 pathway	15
	14

Mechanical shear flow regulates the malignancy of colorectal cancer cells	14
Novel Endoscopic‐Assisted Long Plate Approach for Mandibular Condylar Fracture Reconstruction—A Preliminary Study	14
Multiple intracerebral hemorrhages secondary to eosinophilic granulomatosis with polyangiitis: A case report and literature review	14
EGFR‐TKI plus antiangiogenic agent combination therapy may reduce the incidence of EGFR‐TKI–associated interstitial lung disease in Asian	14
Expression and Clinical Significance of CXCR5 and LAG‐3 on Peripheral Blood CD8⁺ T Cells in Patients With Diffuse Large B‐Cell Lymphoma	13
Cystic neutrophilic granulomatous mastitis: Focus on preoperative cytology and intraoperative consultation	13
Long non‐coding RNA MALAT1 triggers ferroptosis via interaction with FUS to enhance ACSF2 mRNA stabilization in septic acute kidney injury	13
Glycyrrhizic acid protects against temporal lobe epilepsy in young rats by regulating neuronal ferroptosis through the miR‐194‐5p/PTGS2 axis	13
Tacrolimus‐Related Hepatic Sinusoidal Obstruction Syndrome in a Case Receiving Deceased Liver Donor Liver Transplantation	13
In vitro and in vivo effects of Galectin‐3 inhibitor TD139 on inflammation and ERK/JNK/p38 pathway in gestational diabetes mellitus	13
Silencing of lncRNA CRNDE attenuates nonsmall‐cell lung cancer progression by mediating the miR‐455‐3p/HDAC2 axis	13
Mantle Cell Lymphoma of the Thyroid: A Rare Cause of Life‐Threatening Airway Compromise	13
Large Cell Neuroendocrine Carcinoma of the Cervix With Extensive Metastases	13
Silencing of SBF2‐AS1 inhibits cell growth and invasion by sponging microRNA‐338‐3p in serous ovarian carcinoma	12
Primary renal sclerosing epithelioid fibrosarcoma with metastasis to lung after 17 years	12
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Clinical prognosis of surgical resection versus transarterial chemoembolization for single large hepatocellular carcinoma (≥5 cm): A propensity score matching analysis	11
Iron‐deficiency anemia caused by duodenal paraganglioma in an adolescent	11
Issue Information	11
CST1 promotes the proliferation and migration of PDGF‐BB‐treated airway smooth muscle cells via the PI3K/AKT signaling pathway	11
Hepatitis C virus micro‐elimination in people who inject drugs: Challenges and chance in Taiwan and worldwide	11
Obstructive jaundice caused by IgG4‐related disease with multiorgan involvement	11
Issue Information	11
GLIS2 Promotes Epithelial‐Mesenchymal Transition and Gastric Cancer Progression by Regulating BGN to Activate the Wnt/β‐Catenin Pathway	11
Spontaneous resolution of a symptomatic cerebellopontine angle arachnoid cyst in adult: A case report and literature review	11
Bladder cancer‐associated transcript 1 promotes melanoma cell proliferation and invasion via the miR‐374b‐5p/U2‐associated factor homology motif kinase 1 axis	11
Correction to “Circ‐MALAT1 accelerates cell proliferation and epithelial mesenchymal transformation of colorectal cancer through regulating miR‐506‐3p/KAT6B axis”	11
Metabolic syndrome and spatial disparities: The role of socioeconomic deprivation and medical resource availability in the Cijin district, Taiwan	11
Issue Information	11
Higher skin sympathetic nerve activity as a potential predictor of overactive bladder in females refractory to oral monotherapy	10
LncRNA MIR210HG promotes the proliferation, migration, and invasion of lung cancer cells by inhibiting the transcription of SH3GL3	10
Associations of imbalance of intestinal flora with severity of disease, inflammatory factors, adiponectin, and vascular endothelial function of hypertension patients	10
The proliferation and migration of atherosclerosis‐related HVSMCs were inhibited by downregulation of lncRNA XIST via regulation of the miR‐761/BMP9 axis	10
Issue Information	10
Rhaponitin Reverses Cisplatin Resistance and Impairs Cancer Stemness Through HIF‐1α/MCT4/Wnt Pathway in Tongue Squamous Cell Carcinoma	10
Euchromatic histone lysine methyltransferase 2 facilitates radioresistance in prostate cancer by repressing endoplasmic reticulum protein 29 transcription	10
Adult Acute Megakaryoblastic Leukemia in a Mantle Cell Lymphoma Post Treatment and Auto‐Transplant	10
M2 macrophage facilitated angiogenesis in cutaneous squamous cell carcinoma via circ_TNFRSF21/miR‐3619‐5p/ROCK axis	10
TLR9 regulates the autophagy–lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6‐cGAS‐STING pathway	10
Combination of chemotherapy and immunotherapy may overcome the resistance to immunotherapy alone in pulmonary lymphoepithelial carcinoma	10
Y‐Box‐Binding Protein 1 Facilitates the Proliferation and Osteogenic Differentiation of Periodontal Ligament Stem Cells Through the Transcriptional Activation of FGF2‐Mediated Akt/GSK3	10
LncRNA DLEU1 facilitates the progression of oral squamous cell carcinoma by miR‐126‐5p/GAB1 axis	10
Machine Learning–Based Classification of Depression Using Inflammatory Biomarkers in Pancreatic Cancer Patients	10
Issue Information	10
DNMT3b affects colorectal cancer development by regulating FLI1 through DNA hypermethylation	9
Effects of Sofosbuvir/Velpatasvir Therapy on Extrahepatic Manifestations in Patients With Type 2 Diabetes and Chronic Hepatitis C: Insights From a Nationwide Hepatitis C Virus Registry in Taiwan	9
The role of artificial intelligence in the management of liver diseases	9
Proteasome inhibitor bortezomib prevents proliferation and migration of pulmonary arterial smooth muscle cells	9
Complement factor B inhibitor LNP023 mediates the effect and mechanism of AMPK/mTOR on autophagy and oxidative stress in lupus nephritis	9
CircFN1 promotes acute myeloid leukemia cell proliferation and invasion but refrains apoptosis via miR‐1294/ARHGEF10L axis	9

Robotic arm use for upper limb rehabilitation after stroke: A systematic review and meta‐analysis	9
Prediction model of in‐hospital cardiac arrest using machine learning in the early phase of hospitalization	9
Prognostic value of neutrophil‐to‐lymphocyte ratio in gastric cancer patients treated with immune checkpoint inhibitors: A meta‐analysis	9
Advancements in the diagnosis and treatment of renal epithelioid angiomyolipoma: A narrative review	8
	8
Activation of PPARγ regulates M1/M2 macrophage polarization and attenuates dextran sulfate sodium salt‐induced inflammatory bowel disease via the STAT‐1/	8
The effect of dipeptidyl peptidase‐4 inhibitor on incidence and clinical course in bullous pemphigoid patients in a tertiary medical center	8
Kaempferol counteracts bupivacaine‐induced neurotoxicity in mouse dorsal root ganglia neurons by regulating TRAF6‐dependent NF‐κB signaling	8
CMTM5 influences Hippo/YAP axis to promote ferroptosis in glioma through regulating WWP2‐mediated LATS2 ubiquitination	8
Evodiamine inhibits EPRS expression to regulate glutamate metabolism and proliferation of oral squamous cell carcinoma cells	8
A review of cognitive and behavioral outcomes of Brivaracetam	8
Increased serum adipokines are associated with sarcopenia in non‐obese women with rheumatoid arthritis	8
IGF2BP2‐induced circRNF20 facilitates breast cancer cell proliferation via the HuR/CDCA4 axis	8
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Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head	8
Differential expression of host oncogenes in human papillomavirus‐associated nasopharyngeal and cervical epithelial cancers	8
Retraction: ‘ASPM predicts poor prognosis and regulates cell proliferation in bladder cancer’. Zhen‐Ya Gao, Fang Yu, Huan‐Xia Jia, Zhuo Ye, Shi‐Jie Yao, Kao	8
Cuff inflation technique is better than Magill forceps technique to facilitate nasotracheal intubation guiding by GlideScope® video laryngoscope	8
KLF9 inhibits the proliferation, invasion, and migration of renal cell carcinoma through the SDF‐1/CXCR4 axis	8
LncRNA SOX21‐AS1 Promotes the Progression of Pancreatic Cancer by Sponging miR‐9‐3p and Upregulating YOD1	8
RETRACTION: Comparison of the Postoperative Analgesic Effects of Paracetamol–Codeine Phosphate and Naproxen Sodium–Codeine Phosphate for Lumbar Disk Surgery	8
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circUQCRC2 promotes asthma progression in children by activating the VEGFA/NF‐κB pathway by targeting miR‐381‐3p	8
Issue Information	8
Elevated intramuscular adipose tissue content with a high Ishak fibrosis stage (>3) had a negative effect on liver regeneration in cirrhotic patients undergoing portal vein embolization	8
Ultrasound‐guided posterior lateral branches steroid injections of the sacral foramina for chronic new‐onset sacroiliac joint pain management after spinal fusion surgery: A prospective study of single	8
Gypenoside XIII regulates lipid metabolism in HepG2 hepatocytes and ameliorates nonalcoholic steatohepatitis in mice	8
E3 ubiquitination ligase XIAP lightens diabetes‐induced cognitive impairment by inactivating TXNIP‐ERS‐mediated neuronal injury	8
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Impact of Depth of Invasion in Node‐Negative Oral Tongue Cancer Treated With Surgery Alone	7
Predicting Adverse Events in Blunt Chest Trauma: A Novel Nomogram Integrating Vitals, Hemogram, and Comorbidities	7
Circ_0084188 promotes colorectal cancer progression by sponging miR‐654‐3p and regulating kruppel‐like factor 12	7
Reviewer Acknowledgment	7
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Issue Information	7
ZNF521/EBF1 axis regulates AKR1B1 to promote the proliferation, migration, and invasion of gastric cancer cells	7
CircTNPO3 promotes hepatocellular carcinoma progression by sponging miR‐199b‐5p and regulating STRN expression	7
Is it reasonable for the use of Rh‐ee blood? A hospital‐based survey from a southern medical center in Taiwan	7
Duration of the preemptive analgesic effects of low‐ and high‐frequency transcutaneous electrical nerve stimulation in rats with acute inflammatory pain	7
USP21 contributes to the aggressiveness of laryngeal cancer cells by deubiquitinating and stabilizing AURKA	7
Bilirubin metabolism andUDP‐glucuronosyltransferase1A1variants in Asians: Pathogenic implications and therapeutic response	6
Successful intraoperative radiation therapy for a rapidly recurrent smooth muscle tumor of uncertain malignant potential	6
Ethambutol‐induced subacute cutaneous lupus erythematosus	6
Cardiac Angiosarcoma: A Diagnostic and Therapeutic Challenge	6
Tissue and serum miR‐149‐3p/5p in hospitalized patients with inflammatory bowel disease: Correlation with disease severity and inflammatory markers	6
A rare etiology for pulmonary artery dissection: Multiple coronary to pulmonary artery fistulas	6
Laparoscopic wedge hepatectomy for primary hepatic pregnancy	6
Mechanism of miR‐424‐5p promoter methylation in promoting epithelial–mesenchymal transition of hepatocellular carcinoma cells	6
Successful Treatment of Osimertinib Resistance in an EGFR‐Mutant Lung Cancer Patient With a Rare STRN3‐ALK Fusion Using Brigatinib and Osimertinib	6
Issue Information	6
Caregivers' difficulty in managing sleep behaviors of children with attention‐deficit/hyperactivity disorder and related factors during the COVID‐19 pandemic	6
Myeloma‐like Castleman disease with plasmacytosis and monoclonal gammopathy	6
Seronegative Immunoglobulin G4‐related hypertrophic pachymeningitis misdiagnosed as meningitis and meningioma	6
Edematous changes and nail ulcers in hand transplant after SARS‐COV‐2 infection: Unraveling infection or rejection?	6
Effects of Adding Transversus Abdominis Plane Block on Intravenous Nalbuphine and Dexmedetomidine for Severely Pre‐Eclamptic Parturients After Cesarean Delivery	6
Astragaloside IV Alleviates Ulcerative Colitis Progression by Inhibiting WDR5‐Mediated ENO1 H3K4me3 Modification	6
Narrative review of neoadjuvant therapy in patients with locally advanced colon cancer	6
Paeoniflorin inhibits colorectal cancer cell stemness through the miR‐3194‐5p/catenin beta‐interacting protein 1 axis	5
Disc edema in one eye and central serous chorioretinopathy in the other eye shortly after AstraZeneca COVID‐19 vaccination	5
Cancer‐associated fibroblast‐secreted miR‐421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF‐1α axis	5
	5
Correction to “Identification of kinesin family member 3B (KIF3B) as a molecular target for gastric cancer”	5
Issue Information	5
RETRACTED: Role of miR‐490‐3p in blocking bladder cancer growth through targeting the RNA‐binding protein PCBP2	5
Resveratrol improves diabetes‐induced cognitive dysfunction in part through the miR‐146a‐5p/TXNIP axis	5
	5
Response to Integration of the Comprehensive Physical Examination and Diagnostic Tools in Clinical Cardiology	5
Author Index	5
hnRNPA2B1 drives colorectal cancer progression via the circCDYL/EIF4A3/PHF8 axis	5
GLI family zinc finger protein 2 promotes skin fibroblast proliferation and DNA damage repair by targeting the miR‐200/ataxia telangiectasia mutated axis in	5
Dexmedetomidine inhibits the growth and metastasis of esophageal cancer cells by down‐regulation of lncRNA MALAT1	5
Icaritin‐elevated circ_0000190 suppresses the malignant progression of multiple myeloma by targeting miR‐301a	5
Exosomal miR‐181a‐5p derived from SAOS‐2 cells promotes macrophages M2 polarization by targeting RORA	5
Issue Information	5
Integration of the Comprehensive Physical Examination and Diagnostic Tools in Clinical Cardiology	5
Evaluation of sodium‐glucose cotransporter 2 inhibitors for renal prognosis and mortality in diabetes patients with heart failure on diuretics	5
	5
Psychological Capital Moderates the Association Between Social Participation and Depressive Symptoms in Taiwanese University Students	5
LncRNA SNHG14 Delivered by Bone Marrow Mesenchymal Stem Cells‐Secreted Exosomes Regulates Osteogenesis and Adipogenesis in Osteoporosis by Mediating the miR‐27a‐3p/LMNB1	5
LncRNA MIR17HG promotes the proliferation, migration, and invasion of retinoblastoma cells by up‐regulating HIF‐1α expression via sponging miR‐155‐5p	5

Monotropein Induced Ferroptosis to Alleviate the Progression of Hepatocellular Carcinoma via Regulating Nrf2/HO‐1/GPX4 Axis	5
Issue Information	5
Unusual leonine facies: A rare presentation	4
Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine	4
miR‐450a exerts oncosuppressive effects in breast carcinoma by targeting CREB1	4
Well‐controlled viremia reduces the progression of hepatocellular carcinoma in chronic viral hepatitis patients treated with lenvatinib	4
Molecular mechanism of ALKBH5‐mediated m6A demethylation regulating lipopolysaccharide‐induced epithelial–mesenchymal transition in sepsis‐induced acute kidney injury	4
	4
Estimation the Maximum Tolerance Activity of Blood by a Simple Algorithm Method in Pediatric Differentiated Thyroid Cancer Patients Treated With Empirical Radioactive Iodine Dosing Based on	4
Serum HSF1 is upregulated in endometriosis patients and serves as a potential diagnostic biomarker	4
Role of POU1F1 promoting the properties of stemness of gastric carcinoma through ENO1‐mediated glycolysis reprogramming	4
A Preliminary Study on the Therapeutic Role of γδT Cells in Triple‐Negative Breast Cancer	4
Novel mechanism of B cell‐mediated anaphylaxis after spinal anesthesia with bupivacaine	4
Molecular mechanism of WWP1‐mediated ubiquitination modification affecting proliferation and invasion/migration of liver cancer cells	4
Circular RNA Sec61 subunit alpha isoform 1 by competitive absorption of microRNA‐513a‐5p mediates peroxisomal biogenesis factor 5 expression and promotes the malignant phenotype	4
Dupilumab as a rescue therapy for a chronic urticaria patient who showed secondary failure to omalizumab	4
Analysis of macular choroidal thickness in normal Taiwanese eyes by enhanced depth imaging optical coherence tomography	4
Circ_0001666 upregulation promotes intestinal epithelial cell fibrosis in pediatric Crohn's disease via the SRSF1/BMP7 axis	4
	4
Outpatient management of large scalp aplasia cutis congenita without skull defect in a case of Adams‐Oliver syndrome	4
GATA1 Transcriptionally Upregulates LMCD1, Promoting Ferroptosis in Sepsis‐Associated Acute Kidney Injury Through the Hippo/YAP Pathway	4
N6‐methyladenosine‐mediated LINC01087 promotes lung adenocarcinoma progression by regulating miR‐514a‐3p to upregulate centrosome protein 55	4
	4
Same MYH7 gene mutation but different phenotypes of cardiomyopathy in one family	4
A case of upper gastrointestinal bleeding due to pancreatic pseudoaneurysm rupture	4
Primary pulmonary meningioma	4
	4
Glutamate Exacerbates Traumatic Brain Injury‐Induced Acute Lung Injury Through NMDAR/ROS/Ca²⁺ Signaling Pathway in Pulmonary Endothelial Cells	4
A rare case of type 1 autoimmune pancreatitis combined with a pancreatic neuroendocrine tumor	4
	4
Predictive value of hyperhidrosis for the incidence of type 2 diabetes mellitus: A population‐based cohort study in Taiwan	4
The impact of gut microbiota on morbidities in preterm infants	4
Kurarinone alleviates hemin‐induced neuroinflammation and microglia‐mediated neurotoxicity by shifting microglial M1/M2 polarization via regulating the IGF1/PI3K<	4
Smurf1‐targeting microRNA‐136‐5p‐modified bone marrow mesenchymal stem cells combined with 3D‐printed β‐tricalcium phosphate scaffolds strengthen osteogenic activity a	4
Validating the accuracy of the Hendrich II Fall Risk Model for hospitalized patients using the ROC curve analysis	4